POPULARITY
Ungārija un Slovākija bloķē sankcijas pret Krieviju un aizdevumu Ukrainai. Šķietami arvien nestabilāka kļūst partija “Stabilitātei!”. Šomēnes no tās valdes izslēgti vēl divi locekļi – Saeimas deputāti Igors Judins un Jefimijs Klementjevs. Biedrības "Tavi draugi" telpās notiek plakātu darbnīca "Kopā līdz uzvarai!", kuru jau ceturto gadu rīko "Latvijas Platforma attīstības sadarbībai", Fonds atvērtai sabiedrībai "DOTS" un biedrība "Tavi draugi". Ķekavas novada dome lems par Baldones sākumskolas pievienošanu vidusskolai.
No Click Valvar Academy de hoje temos grandes insights sobre a fisiologia dos bloqueios no TAVI.
WORRIED ABOUT THE MARKET? SCHEDULE YOUR FREE PORTFOLIO REVIEW with Thoughtful Money's endorsed financial advisors at https://www.thoughtfulmoney.comToday's guest has been predicting an oncoming boom in the commodity complex for a while now.And increasingly, it's starting to look like that boom is arriving.If so, how high will it go? And how long will it last?And where may the best opportunities lie for investors?For answers, we turn to macro and commodities expert Tavi Costa formely of Crescat Capital. but now newly running his own show at Azuria Capital.#commodities #gold #oilandgas _____________________________________________ Thoughtful Money LLC is a Registered Investment Advisor Promoter.We produce educational content geared for the individual investor. It's important to note that this content is NOT investment advice, individual or otherwise, nor should be construed as such.We recommend that most investors, especially if inexperienced, should consider benefiting from the direction and guidance of a qualified financial advisor registered with the U.S. Securities and Exchange Commission (SEC) or state securities regulators who can develop & implement a personalized financial plan based on a customer's unique goals, needs & risk tolerance.IMPORTANT NOTE: There are risks associated with investing in securities.Investing in stocks, bonds, exchange traded funds, mutual funds, money market funds, and other types of securities involve risk of loss. Loss of principal is possible. Some high risk investments may use leverage, which will accentuate gains & losses. Foreign investing involves special risks, including a greater volatility and political, economic and currency risks and differences in accounting methods.A security's or a firm's past investment performance is not a guarantee or predictor of future investment performance.Thoughtful Money and the Thoughtful Money logo are trademarks of Thoughtful Money LLC.Copyright © 2026 Thoughtful Money LLC. All rights reserved.
Listener feedback, the value of procedural volume for TAVR and MTEER, ventricular arrhythmia in older athletes, and the Goldilocks time horizon for predicting and modifying CV risk are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Procedural Volume and Outcomes for TAVI and M-TEER Operator Procedural Volumes and Outcomes for TAVR and MTEER https://jamanetwork.com/journals/jamacardiology/fullarticle/2843740 II Ventricular Arrhythmia in Older Male Endurance Athletes Myocardial Fibrosis May Raise Arrhythmia Risk in Older Male Endurance Athletes https://www.medscape.com/viewarticle/myocardial-fibrosis-may-raise-arrhythmia-risk-older-male-2026a10001y0 Timing and Relationship of VA With Exercise Patterns in Older Male Endurance Athletes https://doi.org/10.1093/eurjpc/zwag021 III Predicting Cardiac Risk and Statin Use 30-Year ASCVD Risk Among US Adults Aged 30-59 https://www.ahajournals.org/doi/10.1161/CIRCOUTCOMES.125.012348 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net
This episode covers: Cardiology This Week: A concise summary of recent studies What´s new in TAVI? Digital solutions in arrhythmias Mythbusters - Gratitude is heart healthy Host: Emer Joyce Guests: JP Carpenter, Davide Capodanno, Fleur Tjong Want to watch that episode? Go to: https://esc365.escardio.org/event/2528 Want to watch that extended interview on Digital solutions in arrhythmias, go to: https://esc365.escardio.org/event/2528?resource=interview Disclaimer: ESC TV Today is supported by Novartis through an independent funding. The programme has not been influenced in any way by its funding partner. This programme is intended for health care professionals only and is to be used for educational purposes. The European Society of Cardiology (ESC) does not aim to promote medicinal products nor devices. Any views or opinions expressed are the presenters' own and do not reflect the views of the ESC. All declarations of interest are listed at the end of the episode. The ESC is not liable for any translated content of this video. The English language always prevails. Declarations of interests: Stephan Achenbach, Yasmina Bououdina and Nicolle Kraenkel have declared to have no potential conflicts of interest to report. Carlos Aguiar has declared to have potential conflicts of interest to report: personal fees for consultancy and/or speaker fees from Abbott, AbbVie, Alnylam, Amgen, AstraZeneca, Bayer, BiAL, Boehringer-Ingelheim, Daiichi-Sankyo, Ferrer, Gilead, GSK, Lilly, Novartis, Pfizer, Sanofi, Servier, Takeda, Tecnimede. John-Paul Carpenter has declared to have potential conflicts of interest to report: stockholder MyCardium AI. Davide Capodanno has declared to have potential conflicts of interest to report: Abbott Vascular, Bristol Myers Squibb, Daiichi Sankyo, Edwards Lifesciences, Novo Nordisk, Sanofi Aventis, Terumo. Emer Joyce has declared to have potential conflicts of interest to report: Alnylam, Bayer, Pfizer, Fire-1. Konstantinos Koskinas has declared to have potential conflicts of interest to report: honoraria from MSD, Daiichi Sankyo, Sanofi. Steffen Petersen has declared to have potential conflicts of interest to report: consultancy for Circle Cardiovascular Imaging Inc. Calgary, Alberta, Canada. Emma Svennberg has declared to have potential conflicts of interest to report: Abbott, Astra Zeneca, Bayer, Bristol-Myers, Squibb-Pfizer, Johnson & Johnson. Fleur Tjong has declared to have potential conflicts of interest to report: Amsterdam UMC Innovation grant, Heath Holland TKI, Abbott, Dutch Research Council, Boston Scientific.
In this powerful kickoff to 2026, Craig Hemke for Sprott Money welcomes macro strategist and investor Tavi Costa to discuss the massive shifts brewing in global markets. Tavi unveils key macro trends for 2026, including the asymmetric opportunity in energy, the undervaluation in gold and silver mining stocks, and a major capital rotation into hard assets. With inflation risks rising and financial repression likely ahead, Tavi explains why the setup for commodities — especially gold, silver, and copper — is just getting started. They also explore Latin America's investment potential, the mining sector's structural underinvestment, and the role of sovereign actors in driving private market activity. This is essential listening for anyone looking to buy gold or silver, or to understand where the silver and gold prices are headed next.
No episódio de hoje do Check-up Semanal, o Dr. Ronaldo Gismondi, editor-chefe médico do Portal Afya e do Whitebook, comenta os principais destaques recentes em Cardiologia publicados no Portal Afya, reunindo as evidências mais relevantes para a prática clínica atual.Artigos mencionados:• Angioplastia imediata vs. estagiada de lesões não culpadas no IAM com supra de ST• Eficácia e segurança da continuidade da anticoagulação no periprocedimento da TAVI• Colchicina na prevenção de eventos cardiovasculares: o que dizem as evidências?• Deficiência de ferro na insuficiência cardíaca: qual o melhor parâmetro prognóstico?• Eficácia do atenolol no tratamento anti-hipertensivo: novos dados brasileiros
Today we are exploring Left Atrial Appendage Occlusion or LAAO Therapy. We explore the clinical rationale, patient selection, referral pathways and key considerations for LAAO. and aim to understand the therapy as an option for patients who are unsuitable for long term anticoagulation therapy. This is a sponsored podcast.A/Prof Pankaj Jain is an academic interventional cardiologist with appointments at Royal Prince Alfred, Concord, and Macquarie University Hospitals. He is a Clinical Senior Lecturer at the University of Sydney, and Conjoint Senior Lecturer at the University of New South Wales. His interests include complex coronary and structural heart interventions, and mechanical support devices for heart failure.Dr Ata Doost is an Interventional Cardiologist. He completed his training at various hospitals throughout Australia and undertook his speciality fellowship training at Kings College Hospital in London He has appointments at Macquarie University Hospital and National Capital Private & Calvary Bruce Hospitals in Canberra and is a Senior Clinical lecturer at Macquarie University Medical School. Dr Doost has performed thousands of cardiac catheterisations and has extensive experience in structural heart procedures. He specialises in coronary interventions, advanced imaging, and valve therapies including TAVI and MitraClip.
Tavi ha sido visto por un niño y su magia empieza a desvanecerse. Entre risas, luces y un último intento por creer en sí mismo, deberá encontrar la forma de salvar su magia y descubrir si aún puede convertirse en un verdadero elfo de Santa Claus.
No Click Valvar de hoje temos grandes insights sobre sangramentos nos pacientes que se submetem a TAVI.
No Click Valvar Academy de hoje temos grandes insights sobre as performances ventriculares após o TAVI.
Vai Eiropa janvārī beidzot būs gatava parakstīt vērienīgu brīvās tirdzniecības līgumu ar Latīņamerikas valstīm, kas ir pazīstamas kā "Mercosur" bloks? Ziemassvētku tirdziņos Eiropā pastiprināti drošības pasākumi, lai novērstu iespējamus terora aktus. Uz Ukrainu dosies labdarības biedrības "Tavi draugi" kora kocertos savāktie ziedojumi. Somijā pieaug vilku nokosto ziemeļbriežu skaits; somi vaino karu Ukrainā. Krievijas sportisti Pasaules kausa posmā kamaniņu sportā Siguldā nestartēs.
Tavi se une a una clase especial donde los elfos fabrican objetos que dan alegría. Su creación parece no funcionar, pero todos, incluido él mismo, se llevan una enorme sorpresa.
Malachiáš 2,17 – 3,12 17 Unavujete Hospodina svojimi rečami. Pýtate sa: „Čím ho unavujeme?“ Tým, že vravíte: „Každý, kto pácha zlo, páči sa Hospodinovi, takých má rád;“ alebo: „Kde je Boh práva?“ 3, 1 „Pozrite, posielam svojho posla, on mi pripraví cestu. Vtedy zrazu príde do svojho chrámu Pán, ktorého hľadáte; príde posol zmluvy, po ktorom túžite,“ vraví Hospodin zástupov. 2 Kto však znesie deň jeho príchodu? Kto obstojí, keď sa on ukáže? Bude ako oheň taviča, ako lúh bieliča. 3 Tavič sa posadí a prečistí striebro, prečistí Léviho synov a pretaví ich ako zlato a striebro, budú patriť Hospodinovi a správnym spôsobom prinášať obetné dary. 4 Obetné dary Júdu a Jeruzalema budú príjemné Hospodinovi, ako za dávnych dní, ako v dávnych rokoch. 5 „Prídem vás však súdiť, hneď usvedčím čarodejníkov, cudzoložníkov, krivoprísažníkov a tých, čo nádenníkovi ukracujú mzdu, utláčajú vdovu a sirotu, tých, čo cudzinca zbavujú práva a neboja sa ma,“ vraví Hospodin zástupov. 6 „Ja, Hospodin, som sa nezmenil, ani vy ste neprestali byť synmi Jákobovými. 7 Už za čias svojich otcov ste sa odchýlili od mojich ustanovení a nezachovávali ste ich. Vráťte sa ku mne a ja sa vrátim k vám,“ vraví Hospodin zástupov. „Pýtate sa: ‚Ako sa máme vrátiť?‘ 8 Smie človek okrádať Boha? Vy ma okrádate. Pýtate sa: ‚O čo ťa okrádame?‘ O desiatky a pozdvihované obetné dary. 9 Preto vás stíha kliatba, lebo ma okrádate vy, celý tento národ. 10 Prinášajte celé desiatky do zásobárne. Keď bude potrava v mojom dome, potom ma vyskúšajte,“ vraví Hospodin zástupov, „či vám neotvorím okná nebies a nevylejem na vás nadmieru požehnania. A bude po nedostatku. 11 Kvôli vám zabránim škodcom, aby vám neskazili plodiny zeme. Na poli nebude vinič bez plodov,“ vraví Hospodin zástupov. 12 „Blahoslaviť vás budú všetky národy, lebo budete obľúbenou krajinou,“ vraví Hospodin zástupov. Podporovať zvestovanie evanjelia. Podľa svedectva proroka sa mnohí z kňazov aj z veriaceho ľudu stali rebelmi – prestali veriť v Božiu spravodlivosť. Privolávajú síce Boží súd na modlárov, ktorí si žijú v blahobyte, ale sami zasluhujú Božie napomínanie a karhanie. Boha obťažujú tým, že nedávajú do svätyne celú časť určených desatín z úrod. Ba niektorí, ktorí sa navrátili z babylonského zajatia do zasľúbenej zeme, sú natoľko ľahostajní, že nedávajú vôbec nič pre chrámových služobníkov, ktorí sú nemajetní. To je pred Bohom svätokrádežou. Boh bude súdiť tých, ktorí sa Ho neboja. Zasľubuje ale očistenie tých, ktorí prijmú Jeho napomenutia, lebo On zostáva verný, aj keď Jeho ľud zišiel z cesty dodržiavania Jeho nariadení. Svojmu ľudu, ktorý ochotne podporuje slovo Božie a jeho šírenie, zasľubuje Boh nadbytok požehnania a obľúbenosť u iných národov. Veď je napísané: „Čo máš, čo by si nebol dostal?“ (1Kor 4,7b). Aj dnes zvestovanie evanjelia potrebuje financie. Buďme štedrí a úprimní, hľadajme nové spôsoby financovania, aby sa evanjelium dostalo ku všetkým, doma aj vonku. Modlitba: Milujúci Bože, ďakujeme Ti, že nám stále zhovievaš, lebo Ti na nás záleží. Napomínaš nás, aby sme nevybočili z Tvojej cesty a nevypadli z Tvojej milosti. Prečisti naše vnútro a nauč nás ochotne obetovať. Odpusť nám, že náš život v cirkvi, ani vo svete nebýva často na Tvoju ani našu chválu. Amen. Pieseň: ES 332 Autor: Vlasta Okoličányová „Vzmuž sa, všetok ľud krajiny,“ znie výrok Hospodina! „Pracujte, lebo Ja som s vami.“ Aggeus 2,4 Kto skúpo seje, skúpo bude aj žať, kto však seje štedro, štedro bude aj žať. 2.Korinťanom 9,6 Izaiáš 7,10-14 • Modlíme sa za: Hronsek (ZvS) Otázky na rozjímanie: Ako dnes unavujem Boha svojimi rečami alebo skutkami, ktoré spochybňujú Jeho spravodlivosť? Čo pre mňa znamená vrátiť sa k Bohu plnením desiatok a podporou Jeho slova v praxi? Ako môžem štedro prispieť k šíreniu evanjelia, aby som zažil otvorené nebeské okná požehnania? Dnes som vďačný za tieto 3 veci: _________________________________ _________________________________ _________________________________ Viac o vďačnosti, čo to je, prečo je dôležité byť vďačný, ako praktizovať vďačnosť nájdeš na blogu
No Click Valvar Academy de hoje temos grandes insights sobre a correlação entre o uso de Dapagliflozina e TAVI.
Tavi, un pequeño elfo lleno de ilusión, llega por fin a la Escuela de Elfos de Santa Claus. Allí todo es mágico… excepto su larga bufanda, que solo le causa problemas. Cuando un accidente arruina una importante actividad, Tavi deberá decidir si sigue su sueño o renuncia.
Elīza piedzima divu mēnešus par ātru. Viņas sapnis ir staigāt. Pašai. Bet Markusu mēs redzējām tuvplānā Latvijas Televīzijā šovasar dziesmu svētkos. Roka uz sirds. Stāv stalti. Dzied himnu. Tikai mamma zina, ka līdz piecu gadu vecumam dēls pat nestaigāja. Šo bērnu gribas spēks ir neticams. Un vecāku spēja nepagurt – apbrīnojama. Rehabilitācijas centrā “Poga” viņi vingro līdz sviedriem. Labdarības maratons “Dod pieci!” šogad veltīts viņiem. Tāpēc 3 dīdžeji nedēļu strādās Stikla studijā un atskaņos tikai klausītāju izvēlētas dziesmas. Bet vienu no viņiem vēl pieķeram, skrienot gar Raini. Labdarības maratons “Dod pieci!” šogad sabiedrības uzmanību pievērš kustībai – tās nozīmei, iespējām un bieži vien nepiešķirtajai vērtībai. ✋
"Man nav vesela cilvēka organisms un man tāds nekad nebūs. Es dzīvoju savu dzīvi – arī aktīvu dzīvi – ar lielu cieņu pret savu ķermeni, respektējot gan to, kam tas ir gājis cauri agrāk, gan to, kam tas ir izgājis pavisam nesen," rubrikā "Dzīvei nav melnraksta" stāsta Elīna Baltskara. Elīnai 13 gadu vecumā tika diagnosticēts artrīts, kas būtiski ietekmēja viņas kustību un ikdienas spējas. Bija periodi, kad kustība viņai bija liegta, nācās iziet ārstēšanās kursus, fizioterapiju un citas terapijas formas, lai atjaunotu kustības un mazinātu sāpes. #dzīveinavmelnraksta Labdarības maratons “Dod pieci!” šogad sabiedrības uzmanību pievērš kustībai – tās nozīmei, iespējām un bieži vien nepiešķirtajai vērtībai. ✋
An elegant study in post-TAVI atrioventricular block, a PSA for my structural colleagues, revascularization in women, and a CTO PCI trial are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I AV Block After TAVR Heart Blocks During vs After TAVR Show Distinct Patterns https://www.medscape.com/viewarticle/heart-blocks-during-vs-after-tavr-show-distinct-patterns-2025a1000ypp Mechanisms Underlying Alterations in Cardiac Conduction After TAVR https://jamanetwork.com/journals/jamacardiology/fullarticle/2842748 II Related PSA Announcement to My Structural Colleagues III Revascularization Strategies in Women with Severe Chronic CAD Women With Chronic Severe CAD Fare Better With CABG vs PCI https://www.medscape.com/viewarticle/women-chronic-severe-cad-fare-better-cabg-vs-pci-2025a1000ygd PCI vs CABG in Women With Chronic CAD https://doi.org/10.1093/eurheartj/ehaf806 PCI vs CABG - Meta-Analysis of 4 RCTs https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)02334-5/abstract CABG vs Drug-Eluting Stent Implantation for CAD - Meta-Analysis https://www.jacc.org/doi/10.1016/j.jcin.2016.10.008 RECHARGE trial https://therechargetrial.com/ IV A CTO PCI RCT – But don't get your hopes up Early vs Late-Staged PCI After Subintimal Tracking and Re-entry for CTO https://doi.org/10.1016/j.jacc.2025.09.1598 DECISION CTO trial https://pubmed.ncbi.nlm.nih.gov/30813758/ National Inpatient Sample Database PCI CTO Associated With Higher Mortality https://pubmed.ncbi.nlm.nih.gov/37356643/ V Mandrola's Top 10 Stories You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net
The Ugly Sweater Fun Run is coming soon. Tavi Wallace, the ultrarunner who knows no limits, brought Dream Factory CEO Tommie Kendall along to describe its amazing work for children with dire medical needs.Tavi loves shining light on incredible compassionate pursuits, and how runners can help!
On this Weekend Show, Tavi Costa and Dan Steffens walk through where they see real value today: high-quality junior precious and base metal names positioned for M&A, and a structurally tightening energy market led by natural gas and overlooked oil producers. It's a big-picture roadmap for investors who want to own the next leg of the resource bull market. Segment 1 & 2 - Tavi Costa, Partner at Crescat Capital, joins us to share his big-picture outlook on where he sees the best value in the resource space, from junior precious-metal explorers and the majors' slow approach to M&A, to his growing conviction in copper, zinc, and energy (oil and gas) as both key opportunities and a hedge for mining investors. Click here to visit the Crescat Capital website The opinions and information shared by Tavi in this discussion are his own, and not necessarily those of Crescat. Any investments discussed may or may not be held by Crescat. Investments carry risk including risk of loss. Segment 3 & 4 - Dan Steffens, President of the Energy Prospectus Group, wraps up the show sharing his bullish outlook on natural gas driven by winter weather, rising LNG exports, and growing power demand, while also outlining why he believes oil fundamentals remain tighter than current prices suggest and where he sees the best opportunities in oil and gas equities amid an active M&A environment. Click here to visit the Energy Prospectus Group website for more energy market and stock analysis If you enjoy the show, be sure to subscribe to our podcast feed (KER Podcast), YouTube channel, and follow us on X for more market commentary and company interviews. Don't forget to subscribe and leave us a review! For more market commentary & interview summaries, subscribe to our Substacks: The KE Report: https://kereport.substack.com/ Shad's resource market commentary: https://excelsiorprosperity.substack.com/ Investment disclaimer: This content is for informational and educational purposes only and does not constitute investment advice, an offer, or a solicitation to buy or sell any security. Investing in equities and commodities involves risk, including the possible loss of principal. Do your own research and consult a licensed financial advisor before making any investment decisions. Guests may own shares in companies mentioned.
Dr. Emile Daoud, Deputy Editor of JACC Clinical Electrophysiology, discusses Risk Stratification in LBBB after TAVI: Comparison Between a Novel ECG Algorithm and ESC Criteria.
Impact of Cerebral Embolic Protection on Cognition: Experience from BHF PROTECT-TAVI
In this episode of the Heart podcast, Digital Media Editor, Professor James Rudd, is joined by Dr Mehdi Eskandari from King's College Hospital, London. They discuss his paper that attempts to use machine learning to identify patients in whom a TAVI procedure is likely to be unsuccessful, using simple, readily available variables. If you enjoy the show, please leave us a positive review wherever you get your podcasts. It helps us to reach more people - thanks! Link to published paper: https://heart.bmj.com/content/early/2025/07/25/heartjnl-2025-325928
A nova Diretriz de Valvopatias da ESC 2025 chegou e consolidou uma virada histórica: as abordagens transcateter finalmente ganharam protagonismo.No episódio #198 do DozeCast, Mateus Prata e Diandro Mota recebem o Dr. Vitor Emer para revisar de forma crítica e prática o que muda na conduta das valvopatias mais prevalentes — e o que você precisa ajustar na sua tomada de decisão.
Today we are exploring cardiac surgery in elderly patients.This podcast is sponsored by Macquarie University Hospital, part of Macquarie University Health – a trailblazer in healthcare, education and research.Professor Michael Vallely is a leading cardiothoracic surgeon who has clinical and academic interests in minimising the invasiveness of cardiothoracic surgery and is a world authority on total arterial, anaortic, off-pump coronary artery bypass surgery. He also has interests in minimally invasive cardiac surgery (MICS and Da Vinci robotic surgery), transcatheter (TAVI and Mitra-Clip) cardiac surgery, thoracic aortic surgery, geriatric cardiac surgery, and hybrid procedures including the use of ECMO.Dr Nargis Shaheen is a consultant geriatrician with a special interest in perioperative medicine working at Macquarie University Hospital and Concord Hospital. She is a member of the ANZCA perioperative care working group and is involved in perioperative medicine teaching.
IPD Meta-Analysis of Contemporary Trials Comparing TAVI versus SAVR
Acest material poate conține mesaje publicitare și plasare de produse. Unele dintre produsele, serviciile sau brandurile menționate sunt promovate prin parteneriate comerciale, iar prezentarea acestora reprezintă o reclamă.Opiniile exprimate de gazde și invitați sunt personale și nu reflectă neapărat poziția oficială a sponsorilor sau partenerilor noștri. Încurajăm publicul să efectueze propria cercetare înainte de a lua decizii bazate pe informațiile prezentate în acest podcast.
This episode of JACC This Week, hosted by Harlan M. Krumholz, MD, SM, highlights key research and perspectives from the October 14, 2025 issue of JACC. It opens with a call to modernize physician certification by distinguishing core knowledge from clinical reasoning, emphasizing continuous, engaging learning over rote memorization. Featured studies in this week's issue include the cardiovascular risks linked to clonal hematopoiesis in older women, improved clotting outcomes with third-generation LVADs despite ongoing bleeding risks, and how dapagliflozin reduces heart failure events post-TAVI without improving perceived quality of life. The episode also explores inflammation as a target after myocardial infarction, the evolving role of drug-coated balloons in PCI, and cardiac CT's expanding use in prosthetic valve assessment—signaling a shift toward more precise, less invasive cardiovascular care. We also feature an article from JACC: Asia this week on cardiovascular Implications of lipoprotein(a) and its genetic variants in patients from the Middle East.
Two great stories of translation science leading to beneficial drugs in terrible diseases of the heart and the Sisyphean task of predicting the need for pacing after TAVI are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Sotatercept HYPERION Trial https://www.nejm.org/doi/10.1056/NEJMoa2508170 ZENITH Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2415160 Evidence report on treatment for PAH https://icer.org/news-insights/press-releases/icer-publishes-final-evidence-report-on-treatment-for-pulmonary-arterial-hypertension/ PAH Sotatercept Editorial https://www.nejm.org/doi/full/10.1056/NEJMe2503944 II Acoramidis and ATTR Cardiomyopathy ATTRIBUTE-CM Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2305434?logout=true ATTRIBUTE-CM Analysis - Substudy https://www.jacc.org/doi/10.1016/j.jacc.2025.09.013 Tafamadis Trial https://www.nejm.org/doi/full/10.1056/NEJMoa1805689 III Pacing After TAVI Prophylactic pacemaker after TAVI https://www.jacc.org/doi/10.1016/j.jacep.2025.07.028 PROMOTE study https://doi.org/10.1016/j.hrthm.2024.12.019 Evaluation of ESC criteria on RBBB patients undergoing TAVI https://doi.org/10.1016/j.hrthm.2024.11.030 Editorial on Heart Rhythm journal papers https://www.heartrhythmjournal.com/article/S1547-5271(25)00114-6/abstract You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net
Dr. Emile Daoud, Deputy Editor of JACC Clinical Electrophysiology discusses Risk Stratification in LBBB after TAVI: Comparison Between a Novel ECG Algorithm and ESC Criteria.
This past episode was too much! Summer has been doing a lot as usual and not everyone is feeling it. Tavi continues to "demand" her respect from Big Lex, but it's starting to get a little embarrassing. In Addition, with Natalie gone, it seems that Rollie has taken charge, calling the shots this episode! Is Rollie the REAL BADDIES CEO? Tune in and join us in this week's dose of mess! Also check out Tiana's Sims Channel below! Tiana's Sims Channel: https://www.youtube.com/@pettysimproductions NEW EPISODES EVERY TUESDAY AT 4PM =========================== Connect with us! ============================= https://www.instagram.com/randommania1 https://www.instagram.com/jessi.strange https://www.tiktok.com/@pettysimproductions =========================== Subscribe and Listen to the The Petty Headquarters Podcast HERE: =========================== ➡︎YT: @ThePettyHeadquarters ➡︎Apple: https://podcasts.apple.com/us/podcast/is-summer-the-star-of-the-show-baddies-midwest-recap-ep-3-4/id1703678575?i=1000677723578 ➡︎Spotify: https://open.spotify.com/episode/4SAiUiY4ZBfMsax2uIR0ph?si=BFomx4dMQoyKUJZJ8OZjAg Our mission is to stay on top of the mess and make sure we deliver it weekly!
Stijn Schmitz welcomes Tavi Costa to the show. Tavi Costa is Macro Strategist at Crescat Capital. Costa shares a compelling personal journey from Brazil, where experiencing hyperinflation shaped his financial perspective, to becoming a tennis player and eventually a finance professional. His background in macro analysis has enabled him to identify significant market turning points, such as predicting China's potential economic challenges and the emerging commodity trends. Costa emphasizes the importance of independent research and developing strong conviction in investment strategies. He discusses the current bullish environment for gold and silver, highlighting a notable chart showing central banks increasingly preferring gold over treasuries. He believes the current gold market has substantial potential, potentially surpassing historical performance due to unprecedented economic conditions. Regarding silver, Costa presents an intriguing 45-year cup and handle technical pattern, suggesting the potential for silver prices to reach triple digits. He argues that limited silver exploration assets and increasing demand from various sectors could drive significant price appreciation. Moreover, he sees tremendous opportunity in mining companies, noting their impressive profit margins and potential for institutional attraction. Costa is also becoming bullish on energy, presenting a contrarian view based on declining oil inventories, reduced drilling activities, and potential increased energy consumption from technological developments like AI. He sees the energy sector as an undervalued asset class with significant medium-term potential. At Crescat Capital, Costa focuses on early-stage exploration companies, employing a venture capital approach in the mining space. He believes in actively helping management improve capital allocation and exploration strategies. His investment philosophy centers on identifying intrinsic value in companies before market recognition, with a particular focus on metals and resources. Throughout the discussion, Costa emphasizes flexibility in investment thinking, the importance of independent research, and the potential for significant shifts in market perception toward traditionally underappreciated sectors like mining and energy.
This episode covers: Cardiology This Week: A concise summary of recent studies Strategic decisions in valvular heart disease Optimising drug therapy in chronic coronary syndromes Mythbusters: Does wearing a white coat make you smarter? Host: Susanna Price Guests: John-Paul Carpenter, Fabien Praz, Robert Storey Want to watch that episode? Go to: https://esc365.escardio.org/event/2092 Want to watch that extended interview on Optimising drug therapy in chronic coronary syndromes ? Go to: https://esc365.escardio.org/event/2092?resource=interview Disclaimer: ESC TV Today is supported by Bristol Myers Squibb and Novartis. This scientific content and opinions expressed in the programme have not been influenced in any way by its sponsors. This programme is intended for health care professionals only and is to be used for educational purposes. The European Society of Cardiology (ESC) does not aim to promote medicinal products nor devices. Any views or opinions expressed are the presenters' own and do not reflect the views of the ESC. The ESC is not liable for any translated content of this video. The English-language always prevails. Declarations of interests: Stephan Achenbach, Yasmina Bououdina, Nicolle Kraenkel, Fabien Praz and Susanna Price have declared to have no potential conflicts of interest to report. Carlos Aguiar has declared to have potential conflicts of interest to report: personal fees for consultancy and/or speaker fees from Abbott, AbbVie, Alnylam, Amgen, AstraZeneca, Bayer, BiAL, Boehringer-Ingelheim, Daiichi-Sankyo, Ferrer, Gilead, GSK, Lilly, Novartis, Pfizer, Sanofi, Servier, Takeda, Tecnimede. John-Paul Carpenter has declared to have potential conflicts of interest to report: stockholder Mycardium AI. Davide Capodanno has declared to have potential conflicts of interest to report: Bristol Myers Squibb, Daiichi Sankyo, Sanofi Aventis, Novo Nordisk, Terumo. Konstantinos Koskinas has declared to have potential conflicts of interest to report: honoraria from MSD, Daiichi Sankyo, Sanofi. Steffen Petersen has declared to have potential conflicts of interest to report: consultancy for Circle Cardiovascular Imaging Inc. Calgary, Alberta, Canada. Robert Storey has declared to have potential conflicts of interest to report: research grants and personal fees from AstraZeneca and Cytosorbents, and personal fees from Abbott, Afortiori Development/Thrombolytic Science, Boehringer Ingelheim/Lilly, Bristol Myers Squibb/Johnson & Johnson, Chiesi, Idorsia/Viatris, Novo Nordisk, PhaseBio and Tabuk. Emma Svennberg has declared to have potential conflicts of interest to report: Abbott, Astra Zeneca, Bayer, Bristol-Myers, Squibb-Pfizer, Johnson & Johnson.
DOUBLE-CHOICE: Anesthesia strategies and self-expanding valve types for TAVI
Mamas Mamas talks to Jacob Thomsen Lønborg about how PCI affects outcomes for patients with stable CAD undergoing TAVI.
Precious metals are starting to move. Otavio Costa was pounding the table on gold and silver back in 2023. This is a replay of that conversation. I hope you guys enjoy!Hey Guys! This episode, we hear from Tavi Costa, portfolio manager at Crescat Capital, and get his insights into the precious metals industry. Tavi talks about the importance of precious metals CAPEX and explains how the demand for precious metals, specifically gold, affects the industry. He also discusses the differing opinions of gold bears. Tavi shares his thoughts on the inflation super cycle and how it impacts investing criteria. He also talks about identifying mistakes and valuing precious metals equities.[0:00] Who is Tavi Costa?[6:00] Precious Metals CAPEX[22:00] PM Demand: The Use of Gold[33:00] Gold Bears[40:00] The Inflation Super Cycle[50:00] Investing Criteria[59:00] Identifying Mistakes[1:08:00] Valuing PM Equities[1:19:00] More from Tavi Costa and Closing QuestionsIf you enjoyed this podcast, please check out Otavio on Twitter @TaviCosta and read his latest research at Crescat Capital. Finally, thanks to the following sponsors for making the podcast a reality!MitimcoThis episode is brought to you by MIT Investment Management Company, also known as MITIMCo, the investment office of MIT. Each year, MITIMCo invests in a handful of new emerging managers who it believes can earn exceptional long-term returns to support MIT's mission. To help the emerging manager community more broadly, they created emergingmanagers.org, a website for emerging manager stockpickers.I highly recommend the site for those looking to start a stock-picking fund or learn how others have done it. You'll find essays and interviews by successful emerging managers, service providers used by MIT's own managers, essays MITIMCo has written for emerging managers, and more!
Afinal, dá para fazer TAVI na insuficiência aórtica (IAo) com segurança? Neste episódio, Mateus Prata e Raphael Rossi destrincham a fisiopatologia da IAo, por que a ausência de calcificação torna a ancoragem um pesadelo técnico, o que já aprendemos com o uso off-label de plataformas para estenose aórtica, e como as próteses dedicadas (ex.: JenaValve Trilogy) e os dados do ALIGN-AR estão mudando o jogo. Tem indicação hoje? Onde ainda é o desafio? E o que esperar do futuro?Você vai ouvir:Panorama da IAo: etiologias, remodelamento e o “ponto de inflexão” clínico.Por que TAVI na IAo é difícil: anel complacente, sem cálcio, sizing e PVL/migração.O que deu (e não deu) certo com válvulas de EAo na IAo.Próteses dedicadas e ALIGN-AR: mecanismo de ancoragem ativa, vedação e resultados funcionais.Minutagem:(01:39) - Devo considerar TAVI na IAo?(03:35) - A importância na prática clínica da IAo(08:12) - Complicadores da IAo(11:40) - O que acontece com a PA na IAo(12:50) - As vantagens da cirurgia de troca valvar na IAo(16:40) - Os desafios da TAVI na IAo(20:20) - Quais são as próteses disponíveis para TAVI na IAo?(27:45) - No cenário atual, quando a TAVI é uma opção na IAo?(28:42) - Marcapasso no pós TAVI de IAo(30:00) - O futuro da TAVI na IAo_____________________________Assine agora! Revisões didáticas de Cardiologia, semanalmente na DozeNews PRIME: a maneira mais leve e rápida de se manter atualizado(a), através do link dozeporoito.com/prime
Is silver finally ready to explode higher? Crescat Capital's Tavi Costa joins Wealthion's Trey Reik to share why he believes silver is entering a powerful new bull market, and why most investors still don't see it coming. From surging industrial demand for solar and AI infrastructure, to a historic supply crunch and under-the-radar central bank buying, Tavi explains why silver may be the most undervalued macro asset on the planet.
Is silver finally ready to explode higher? Crescat Capital's Tavi Costa joins Wealthion's Trey Reik to share why he believes silver is entering a powerful new bull market, and why most investors still don't see it coming. From surging industrial demand for solar and AI infrastructure, to a historic supply crunch and under-the-radar central bank buying, Tavi explains why silver may be the most undervalued macro asset on the planet.
No episódio de hoje do check-up semanal, nosso editor-chefe médico, Ronaldo Gismondi, traz os principais destaques do mês sobre cardiologia abordados no Portal Afya.Confira os temas do episódio de hoje sobre cardiologia: Eficácia do acoramidis no tratamento da amiloidose ATTR; Biomarcadores hepáticos têm valor prognóstico na ICFEP?; Troponina para estimativa de risco cardiovascular; Lipoproteína (a): Consenso Internacional de Bruxelas aborda o tema; Proteção cerebral durante a TAVI. Aperte o play e ouça agora os destaques!
Wassup Petty Posse! It's been a minute since we last spoke! It's good to be back from our month-long hiatus! We had a lot of catching up to do and we are finally here with a WHOLE CATCH UP BADDIES AFRICA RECAP! There's a lot to unpack from Elsie Kay and Tavi's beef all the way to Lex's hypocritical behavior. We say our thoughts on it ALL! So Tune in for your dose of mess!
“The U.S. Treasury's gold reserves are at one of the lowest levels in 90 years,” says Tavi Costa, partner and portfolio manager at Crescat Capital, joining Daniela Cambone on the Daniela Cambone Show. “At just 2% of total government debt, this imbalance is a green light for long-term gold investors.”Costa warns that rising U.S. debt, surging interest costs, and the likelihood of dollar devaluation will eventually force the government to either buy more gold or revalue it, a move he believes could unlock massive upside for the metal. “The world is accumulating gold, and the U.S. will have to join in,” he says. Beyond gold, Costa shares why the AI arms race and a coming infrastructure boom could reshape the U.S. economy, creating major opportunities in raw materials and engineering sectors.The opinions and information shared by Tavi in this discussion are his own, and not necessarily those of Crescat. Any investments discussed may or may not be held by Crescat. Investments carry risk including risk of loss. ✅ FREE RESOURCESDownload the Ultimate Decision-Making Guide on Gold & Silver plus Daniela Cambone's Top 10 Lessons to safeguard your wealth (FREE)
In this podcast interview, Tavi Costa from Crescat Capital discusses the emerging bullish cycle in the metals and mining sector, highlighting several key macro trends and investment opportunities. Costa believes we are in the early stages of a long-term commodity cycle, with gold leading the way and other metals poised to follow. The discussion centers on three primary pillars: energy sources, infrastructure, and raw materials. Costa argues that the increasing electricity demand, driven by artificial intelligence and onshoring trends, will create significant opportunities in metals and mining. He emphasizes the critical need for metals to support emerging technological and infrastructure developments, particularly in the United States. A pivotal moment Costa highlights is the U.S. Department of Defense's 15% stake in MP Materials, which he sees as a recognition of strategic material vulnerabilities. This investment signals a potential shift in how governments view critical resources and mining infrastructure. Costa also discusses the potential macroeconomic trajectory, suggesting two potential paths: a deflationary shock or an inflationary era followed by a highly efficient, deflationary period driven by AI. He believes we are currently in an inflationary buildup phase that will eventually transition to increased productivity and efficiency. Regarding currencies, Costa anticipates a long-term decline in the U.S. dollar versus other currencies, driven by significant fiscal and trade deficits. He sees this as part of a broader "domino effect" of macro trends, where acceptance of risk gradually moves through different asset classes and markets. The interview concludes with Costa identifying the exploration and development phase of the mining industry, alongside emerging markets, as potentially the most asymmetric investment opportunities of his career. He encourages investors to pay attention to the interconnected nature of these macro trends and the gradual rotation of capital across different sectors and geographies.
Host Sotirios Evangelou, MD, FSCCT is joined by Vlasis Ninios, MD to explore the indispensable role of cardiac CT in transcatheter structural heart interventions. From planning TAVI and TMVR to assessing tricuspid valve therapies, they highlight how CT imaging guides prosthesis sizing, vascular access, and risk assessment. Together, they discuss emerging technologies, evolving indications, and how cardiac CT is shaping the future of structural heart disease treatment.
Featuring articles on routine cerebral embolic protection for TAVI, and treatments for cirrhosis due to MASH, BRAF V600E metastatic colorectal cancer, and Pompe's disease; a new review article series on medical education; a case report of a woman with dyspnea on exertion; and Perspectives on addressing ultraprocessed foods, on the costs of dismantling DEI, and on a brother's keeper.
Today Guy talks about word eizé, “what a,” a word we frequently use in various contexts. How do we use it, and what happens when we add it to mashehu, “something,” or mishehu, “someone”? Hear the All-Hebrew Episode on Patreon New Words and Expressions: Eizo mis'ada – What a restaurant – איזו מסעדה Eize mis'ada (coll.) / Ssssé mis'ada – What a restaurant – איזה מסעדה Eize basa – What a bummer – איזה באסה Eize ben adam – What a person – איזה בן אדם Eize fashla – What a mess-up – איזה פשלה Eize hagzamot! – Such exaggeration! – !איזה הגזמות Eize hisachfut! – That's so over-the-top! – !איזה היסחפות Eize keta/kta'im – How funny/What a surprise – איזה קטע/קטעים Eize keif lishmo'a – So happy to hear (the news) – איזה כיף לשמוע Eize yoffie – How great – איזה יופי Eize nefila – What a flop – איזה נפילה Eize fisfus – What a bummer – איזה פספוס Wow, eize rishmiyut – Wow, such formality – וואו, איזה רשמיות Eize hultsa lilbosh, zot o zot? – Which shirt should I wear, this one or that one? – איזה חולצה ללבוש, זאת או זאת Eize rofe – Which doctor – איזה רופא (Be-) eize yom? – On what day? – איזה יום Chikiti eize sha'a – I waited for like an hour – חיכיתי איזה שעה Tamlits li al eize sefer – Could you recommend a book for me? – תמליץ לי על איזה ספר Haya sham eize mishehu – There was some guy there – היה שם איזה מישהו Tavi eize mashehu – Get me something – תביא איזה משהו Playlist and Clips: Dudu Tassa – Eize Yom (lyrics) Dalia Amihud – Eize Ben Adam (lyrics) Ep. no. 51 about yofi Ep. no. 108 about basa, bummer Ep. no. 112 about rishmiyoot, formality Ep. no. 115 about fisfoos, loss Ep. no. 118 about nefila, flop Ep. no. 132 about keta, gag Ep. no. 137 about hagzamot, exaggerations Ep. no. 143 about fashla, mess-up
Why can't you divide by zero? Neil deGrasse Tyson and Chuck Nice discuss higher dimensions, dividing by zero, and math's unsolved questions with math YouTuber Grant Sanderson (3blue1brown).NOTE: StarTalk+ Patrons can listen to this entire episode commercial-free here:https://startalkmedia.com/show/the-language-of-the-universe-with-grant-sanderson-3blue1brown/Thanks to our Patrons Nicolas Alcayaga, Ryan Harris, Ken Carter, Ryan, Marine Mike USMC, VARD, Mile Milkovski, Gideon Grimm Gaming, Shams.Shafiei, Ben Goldman, Zayed Ahmed, Matt Nash, Stardust Detective, Leanice, morgoth7, Mary O'Hara, David TIlley, Eddie, Adam Isbell-Thorp. Armen Danielyan, Tavi, Matthew S Goodman, Jeremy Brownstein, Eric Springer, Viggo Edvard Hoff, Katie, Kate Snyder, Jamelith, Stanislaw, Ringo Nixon, Barbara Rothstein, Mike Kerklin, Wenis, Ron Sonntag, Susan Brown, Anti alluvion, Basel Dadsi, LoveliestDreams, Jenrose81, Raymond, David Burr, Shadi Al Abani, Bromopar, Zachary Sherwood, VP, Southwest Virginia accountability, Georgina Satchell, Nathan Arroyo, Jason Williams, Spencer Bladow, Sankalp Shinde, John Parker, Edward Clausen Jr, William Duncanson, Mark, and Dalton Evans for supporting us this week. Subscribe to SiriusXM Podcasts+ to listen to new episodes of StarTalk Radio ad-free and a whole week early.Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.
Tom welcomes back Tavi Costa, Portfolio Manager at Crescat Capital, to discuss the current state of gold, silver, mining stocks, and broader economic trends. Costa emphasizes that despite technical indicators suggesting overbought conditions in gold, the underlying macroeconomic factors point to continued strength in precious metals. He highlights the role of central banks, particularly in emerging markets like China, Russia, and Turkey, which have been significant buyers of gold. Costa argues that gold's revaluation is driven by global debt imbalances, de-globalization trends, and countries seeking to stabilize their monetary systems. He also explains how higher gold prices can increase the U.S. Treasury's cash reserves, enabling buybacks of Treasuries without quantitative easing, which he believes will be a critical tool for managing debt. Costa is bullish on mining stocks, noting they are historically undervalued relative to U.S. equities and have outperformed over the past decade. He suggests that as global infrastructure needs grow and supply chains shift, mining companies will play a crucial role in meeting demand for essential commodities. Additionally, he points out the attractive valuations of silver, given its high gold-to-silver ratio, which he believes could lead to significant price appreciation. The discussion also touches on the U.S. dollar's structural downtrend, driven by high debt levels and interest payment burdens, and how this impacts emerging markets positively. Costa predicts that lower yields on short-term Treasuries will benefit miners and other sectors. He concludes by advocating for increased exposure to energy stocks due to geopolitical tensions and rising oil prices. Time Stamp References:0:00 - Introductions0:38 - Technical Bear Signals?5:54 - Monetizing U.S. Assets11:08 - Gold Re-Valuation Chart15:00 - Tariffs & Fed Policy20:08 - Dollar Struct Downtrend26:10 - Mining Stock Value31:30 - A Correction Coming?35:33 - GS Ratio Imbalances40:09 - Gaining Metal Exposure43:43 - Education & Sentiment47:00 - Mkt. Rotation & Wrap Up Guest Links:X: https://x.com/tavicostaX: https://x.com/crescat_capitalWebsite: https://crescat.net Otavio ("Tavi") Costa is a Member and Portfolio Manager at Crescat Capital and has been with the firm since 2013. He built Crescat's macro model that identifies the current stage of the U.S. economic cycle through a combination of 16 factors. His research is regularly featured in financial publications such as Bloomberg, The Wall Street Journal, CCN, Financial Post, The Globe and Mail, Real Vision, and Reuters. Tavi is a native of São Paulo, Brazil, and fluent in Portuguese, Spanish, and English. Before joining Crescat, he worked with the underwriting of financial products and international business at Braservice, a large logistics company in Brazil. Tavi graduated cum laude from Lindenwood University in St. Louis with a B.A. degree in Business Administration with an emphasis in Finance and a minor in Spanish. Tavi played NCAA Division 1 tennis for Liberty University.