Podcasts about Replacement

  • 5,417PODCASTS
  • 9,370EPISODES
  • 35mAVG DURATION
  • 4DAILY NEW EPISODES
  • Jun 3, 2026LATEST

POPULARITY

20192020202120222023202420252026

Categories



Best podcasts about Replacement

Show all podcasts related to replacement

Latest podcast episodes about Replacement

Bannon's War Room
Episode 5417: MSM Freakout Over New DNI Director; The Great AI Replacement

Bannon's War Room

Play Episode Listen Later Jun 3, 2026


Episode 5417: MSM Freakout Over New DNI Director; The Great AI Replacement

Morning Wire
Evening Wire: Why Google Wants to Release 32 Million Mosquitoes & Tulsi's Replacement Tapped | 6.2.26

Morning Wire

Play Episode Listen Later Jun 2, 2026 12:57


Marco Rubio gives updates on Iran, the president taps a familiar name to replace Tulsi Gabbard, and Google is seeking approval to release 32 million mosquitos in California and Florida. Get the facts first with Evening Wire. - - - Ep. 2819 - - - Wake up with new Morning Wire merch: https://bit.ly/4lIubt3  - - - Today's Sponsor: Lean - Get started with 20% off and free rush shipping so you can add LEAN to your healthy diet and exercise plan. Visit takelean.com and enter WIRE at checkout.  - - - Privacy Policy: ⁠https://www.dailywire.com/privacy⁠ morning wire,morning wire podcast,the morning wire podcast,Georgia Howe,John Bickley,daily wire podcast,podcast,news podcast Learn more about your ad choices. Visit podcastchoices.com/adchoices

The Jason Rantz Show
Hour 2: Capitol Hill street takeover, Snohomish County homelessness rises, Wild Waves replacement

The Jason Rantz Show

Play Episode Listen Later Jun 2, 2026 47:55


Senior Citizens in Capitol Hill are complaining about the chaos erupting on the streets every night. Homelessness has ticked up in Snohomish County. Seattle’s office collapse hits a trophy tower, and the price tag is brutal. // Big Local: Wild Waves in Federal Way is being replaced by the most boring thing imaginable. Police have released body cam footage of Longview Schools Superintendent Karen Cloninger’s arrest. Tacoma residents are thrilled that Sound Transit still plans to build a light rail line. // You Pick the Topic: A New York landlord is in the middle of a 9-year legal battle with a squatter.

Stonemaier Streams
10 Product Design Mistakes That Cause the Most Replacement Parts Requests

Stonemaier Streams

Play Episode Listen Later Jun 1, 2026 5:37


https://stonemaiergames.com/10-product-design-mistakes-that-cause-the-most-replacement-parts-requests/

Viper Rambles
Rockstar's Weird Spanish Promotion, AI and The Loss of Shared Media, AI Deception and Job Replacement | Viper Rambles #6

Viper Rambles

Play Episode Listen Later May 30, 2026 21:22


0:00 Rockstar & Twitch's Weird Spanish Promotion | Sept 3, 2025 4:13 AI-Generated TV Shows & The Loss of Shared Media | July 31, 2025 7:09 AI Deception, Uncanny Bunnies, and Job Replacement | July 31, 2025 11:30 Drama Grifters vs. Video Essayists | Aug 7, 2025 12:56 My Doppleganger or My Second Channel? | Aug 28, 2025 14:47 Modern Fast Food Architecture is Getting Worse? | Aug 28, 2025 19:50 My Favorite Sandwich | Aug 28, 2025

Everything is Black and White - a Newcastle United podcast
Anthony Gordon to Barcelona: Why it's the perfect sales pitch for Newcastle United | Abde Ezzalzouli could be the exciting replacement

Everything is Black and White - a Newcastle United podcast

Play Episode Listen Later May 29, 2026 38:51


Hello! Lee Ryder is back on The Everything is Black and White Podcast to discuss the exit of Anthony Gordon to Barcelona, and the race to replace him! --- As always a big thanks to our sponsors NORD VPN and Saily - two products that will enhance your travel abroad. NORD VPN providing the safety and security you need while browsing, and Saily giving you that affordable e-sim and network coverage. You can get discounts by hitting up the links in the description box. EXCLUSIVE NordVPN Deal ➼ ⁠https://nordvpn.com/toon⁠ Try it risk-free now with a 30-day money-back guarantee

The LA Report
OC officials help evacuees vote, Loopholes for AI data centers, LA Phil announces Dudamel's replacement — Evening Edition

The LA Report

Play Episode Listen Later May 27, 2026 4:52


Orange County's registrar is traveling to evacuation centers near Garden Grove to help residents vote. A report says California data centers use loopholes to hide their water use. The L.A. Philharmonic announces its new music director. Plus, more from Evening Edition. Support The L.A. Report by donating at LAist.com/join and by visiting https://laist.comSupport the show: https://laist.com

The Higher Standard
Zuckerberg Just Said That At Meta, Your Job Is Training Its Replacement

The Higher Standard

Play Episode Listen Later May 26, 2026 84:24 Transcription Available


AI is no longer just helping you write emails or clean up spreadsheets; it is watching, learning and preparing to do the job itself. In this episode, Chris and Saied break down Zuckerberg's stunning explanation of employee-trained AI, the corporate obsession with cutting headcount in the name of “efficiency,” Elon Musk's robot economy and the trillions in wages suddenly sitting in the crosshairs. Add a labor market nobody fully trusts and a bond market flashing warnings, and one question remains: when productivity explodes, who still gets a paycheck?

Irish Tech News Audio Articles
Chartered Accountants Ireland calls for AI-ready infrastructure and SME supports and rejects "replacement" narrative ?

Irish Tech News Audio Articles

Play Episode Listen Later May 22, 2026 6:19


As Chartered Accountants Ireland surpasses 40,000 members, it has today published a new position paper on the future of AI and accountancy. The largest professional body on the island of Ireland is calling on Government to invest in AI-ready infrastructure, strengthen supports for SME adoption and embed AI skills and literacy across the education system. The position paper was launched alongside Deputy Malcolm Byrne T.D., Chair of the Oireachtas Committee on Artificial Intelligence. Accountants as trusted advisors The paper argues that in an AI-driven economy, accountants will play an increasingly important role as trusted business leaders providing governance, ethical oversight and assurance. While the paper acknowledges that AI will bring change to how the profession operates, it reinforces – rather than diminishes – the role accountants play in supporting robust, accountable decision-making. The Institute also challenges the narrative that accountants are at risk of being replaced by AI, highlighting instead how the profession is evolving alongside the technology. It emphasises that accountants must take a leading role in implementing AI within finance functions, ensuring systems are deployed responsibly, controls are robust, and outputs can be trusted. Rosemary Keogh, CEO, Chartered Accountants Ireland said "There is a common belief that AI will replace accountants, but the evidence simply doesn't support that. It reflects a misunderstanding of what modern accountants actually do. AI is automating routine, rules-based work and most accountants welcome that. It frees them up to focus on higher-value roles like strategy, risk and decision making. "The AI economy will run on trust. While AI can process extraordinary volumes of data, automate complex tasks, and generate insights at unprecedented speed, trust in those outputs depends on human oversight, ethical judgement and professional accountability. As AI systems become more widely used, the need for trusted financial information will only grow – and this is where accountants add real value." Accountants are already using AI across audit, reporting and advisory services, with recent research by Chartered Accountants Worldwide pointing to strong enthusiasm across the profession. 85% of respondents indicated a willingness to use AI tools in their work, with the younger generation overwhelmingly open to using these tools at 91%. The new position paper aims to provide leadership and clarity on how accountants can use the technology responsibly and effectively. Government policy needed to support AI adoption Chartered Accountants Ireland is calling for Government to support responsible AI adoption in several ways, noting that AI matters not just for accountants, but for Ireland. The paper sets out several recommendations, including: SMEs need to be supported on their AI journey – Supports from Enterprise Ireland, Local Enterprise Offices, and others need to be more accessible, and SMEs and their workforces given the opportunity to become AI literate cost-effectively. Investment in AI-ready infrastructure – For AI to work effectively, Ireland requires an underlying infrastructure that is strong, sustainable, and resilient. From data centres to electricity generation and investments in the national grid, the rightfoundations are needed to optimise the use of AI. Leading on EU simplification and AI regulation – During its upcoming EU Presidency, Ireland has a unique opportunity to lead on the EU's digital simplification package. Ireland should focus on ensuring regulations are proportionate for businesses and promoting the development of guidance and tools that enable businesses to apply AI productively and responsibly. Embedding AI literacy in education – courses in secondary schools and in further and higher education need to be adapted so that all young people are AI literate and aware of the technology's benefits, opportunities, and dangers. ACA syllabus world-leading in tec...

Choose 2 Think
404: Let the Light in! (Part 3 in the Spring Reset for Your Mind Series)

Choose 2 Think

Play Episode Listen Later May 21, 2026 19:15


Join Victoria as she explores the transformative power of light and renewal in the mind, emphasizing gentle, intentional practices rooted in faith and neuroscience to foster peace, clarity, and spiritual growth.key topicsMind renewal through gentle practicesThe role of light and gratitude in mental healthNeuroscience of thought pathways and changeChapters00:00The Power of Light in Our Lives01:23 The Series on Spring Reset: A Spiritual and Mental Refresh02:28 Clearing the Corners: Recognizing Mental Clutter03:24 Inviting Light: Creating Space for Renewal04:20 Neuroplasticity and the Power of Replacing Thoughts05:12 The Process of Mind Renewal: Gradual and Repetitive06:37 Casting Out Fearful Thoughts with Truth07:30 Practicing Rest and Peace in Daily Life08:23 The Impact of Rehearsing Truth Over Fear09:21 Living Light and Not Heavy: The Invitation from Jesus10:37 A Personal Story of Hope and Light by the Lake12:02 The Power of Replacement and Gratitude13:24 Gratitude as a Brain-Transforming Practice14:51 Creating a Healthy Thought Environment16:09 One Truth at a Time: Practical Steps for Renewal17:05 Inviting God's Gentle Light into Your Mind17:59 Closing Thoughts: Living a Light-Filled Lifekeywords: mind renewal, spiritual growth, neuroscience, gratitude, light, mental health, faith, inner peace, neuroplasticity, Christian living

Joe Giglio Show
Will Howie Roseman Draft Jalen Hurts' Replacement in 2027?

Joe Giglio Show

Play Episode Listen Later May 21, 2026 23:37


Joe Giglio and Hugh Douglas explore if Howie Roseman is positioning the Eagles to draft a new quarterback by targeting 2027 draft picks. They compare Jalen Hurts' career path to Donovan McNabb and discuss Aaron Nola's concerning decline with the Phillies. 01:00 - Eagles Trade Speculation 04:22 - Future Quarterback Succession Plan 14:45 - Aaron Nola Performance Debate 18:35 - Listener Input and Analysis

Kevin and Cory
Mavericks Clear House: Jason Kidd Out as Search for Replacement Begins

Kevin and Cory

Play Episode Listen Later May 20, 2026 9:48


Patrick Dumont's decision to move on from Jason Kidd and Nico Harrison signals a complete organizational reboot for the Dallas Mavericks. They examine the emotional toll of the Luka Dončić trade on the fan base and debate how star rookie Cooper Flagg will navigate the team's ongoing instability.

Shan and RJ
Hour 4: Replacement names for Jason Kidd as the next Mavs head coach

Shan and RJ

Play Episode Listen Later May 20, 2026 41:49


Replacement names for Jason Kidd as the next Mavs head coach. The Red Zone: John Harbaugh's shots fired at the Cowboys.

The Joe Show
JUDGEjoeSHOW (Father's Day Replacement) Part 1

The Joe Show

Play Episode Listen Later May 20, 2026 7:30 Transcription Available


This morning we have a wife who is taking her husband to court because of a botched Mother's Day. Is she entitled to a day of her own? Or will she be awarded nothing? See omnystudio.com/listener for privacy information.

The Joe Show
JUDGEjoeSHOW (Father's Day Replacement) Part 2

The Joe Show

Play Episode Listen Later May 20, 2026 5:59 Transcription Available


We get a final verdict for Mom V. Husband in this edition of JUDGEjoeSHOW! Stream both parts now on the iHeart Radio App or wherever you listen to podcasts! See omnystudio.com/listener for privacy information.

The Health Courage Collective
255: Are You Quietly Capping Your Potential?

The Health Courage Collective

Play Episode Listen Later May 20, 2026 11:42 Transcription Available


Aging at an elite level requires acting strategically right now, while you're in your 40s and 50s to give your future self an advantage.  Not just biologically, but also mentally.  The way you choose the things you want to work toward affects whether you're going to be able to push the envelope in terms of what you're capable of becoming in your 70s 80s and beyond.come to my website: www.healthcouragecollective.comAre you ready to give your cells their best chance to not have to stop living before they die by allowing them access to physiologic levels of hormones, but aren't sure how to even get started?  Join the waitlist for my new beta program here and help me figure out how best to help wonderful women like you get the hormone care they deserve!Join the Waitlist HereCome visit me: www.healthcouragecollective.comemail me: healthcouragecollective@gmail.com

Deadline: White House
"The replacement of the DOJ's 154-plus-year-old mission"

Deadline: White House

Play Episode Listen Later May 19, 2026 45:33


A key focus today: a $1.8 billion settlement of our taxpayer dollars to be used to compensate people who claim to be targeted by the Justice Department — January 6th insurrectionists.  For more from Nicolle, follow and download her podcast, “The Best People with Nicolle Wallace,” wherever you get your podcasts.To listen to this show and other MS podcasts without ads, sign up for MS NOW Premium on Apple Podcasts. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Capital City Soccer Show
Nico and Rodo Out w/ Adrian Healey, Replacement Options, St Louis City Preview, and more

Capital City Soccer Show

Play Episode Listen Later May 19, 2026 95:19


This week, Landon and Jeremiah are joined by Adrian Healey to discuss the firing of Nico Estevez and Rodolfo Borrell. Other questions and topics include:- Nico and Rodo are out!- Grading Rodo's performance- Who will replace him?- Why these games led us here- Potential coach options- How attractive is the Austin job?- Will Austin get a third kit this year?- St Louis Preview- Adrian and Coach Cowell's new podcast- Free Parking at Amplify- much moreMoontower Soccer is brought to you by FVF LawSupport the show

OTB Football
FOOTBALL DAILY: Maresca the Pep replacement | Arsenal on brink of PL title | Gordon and Neymar make WC squads

OTB Football

Play Episode Listen Later May 19, 2026 13:16


On Tuesday's Football Daily, Phil Egan brings you news from the Premier League, the League o Ireland and the World Cup.Arsenal move to the brink of a first Premier League title in 22 years after a narrow 1-0 victory over Burnley at the Emirates.Mikel Arteta praises his squad's mentality after keeping four consecutive clean sheets in all competitions.Kai Havertz scores the decisive goal from a Bukayo Saka corner as Arsenal move five points clear at the top.Declan Rice admits Arsenal felt the pressure during a tense finish against relegated Burnley.Manchester City prepare for a huge clash with Bournemouth knowing anything less than a win could hand Arsenal the title.Multiple reports claim Pep Guardiola will leave Manchester City this summer after a trophy laden decade at the Etihad.Former Chelsea boss Enzo Maresca emerges as the favourite to replace Guardiola at City.Guardiola reflects on his time in Manchester and the memories created during his spell in English football.Bournemouth manager Andoni Iraola targets European qualification ahead of his final home game in charge.Tottenham boss Roberto De Zerbi insists his squad deserves to remain in the Premier League ahead of a crucial trip to Chelsea.Harry Kane backs Spurs to survive while Chelsea interim boss Calum McFarlane focuses on ending the season strongly.Jose Mourinho is linked with a sensational return to Real Madrid, with debate continuing over his place in the modern game.Waterford secure their first SSE Airtricity Men's Premier Division win of the season thanks to Tommy Lonergan's dramatic late penalty against Drogheda.Southampton face an independent commission hearing over alleged unauthorised filming ahead of their Championship play-off semi-final.Scotland name Ross Stewart in their World Cup squad while veteran goalkeeper Craig Gordon earns another call-up at the age of 43.Neymar returns to Brazil's World Cup squad for 2026, but Chelsea forward Joao Pedro misses out on Carlo Ancelotti's final selection.Become a member and sign up at offtheball.com/join

KMJ's Afternoon Drive
Measure C Replacement Fails & Amazon Urns

KMJ's Afternoon Drive

Play Episode Listen Later May 19, 2026 16:25


A proposed replacement for Fresno County’s Measure C has failed its initial signature test, delaying its path to the November ballot. Officials say too many duplicate signatures were found in the sample, forcing a full manual review of all petitions. While it could still qualify, election leaders warn the timeline is now tight, putting the measure’s chances in jeopardy. An Inland Empire family says they were stunned after discovering what appeared to be someone else’s ashes inside an urn they bought on Amazon. The family is now trying to track down the person’s loved ones, but says responses from Amazon and the seller have been slow and frustrating. Please Like, Comment and Follow 'Philip Teresi on KMJ' on all platforms: --- Philip Teresi on KMJ is available on the KMJNOW app, Apple Podcasts, Spotify, YouTube or wherever else you listen to podcasts. -- Philip Teresi on KMJ Weekdays 2-6 PM Pacific on News/Talk 580 AM & 105.9 FM KMJ | Website | Facebook | Instagram | X | Podcast | Amazon | - Everything KMJ KMJNOW App | Podcasts | Facebook | X | Instagram See omnystudio.com/listener for privacy information.

Philip Teresi Podcasts
Measure C Replacement Fails & Amazon Urns

Philip Teresi Podcasts

Play Episode Listen Later May 19, 2026 16:25


A proposed replacement for Fresno County’s Measure C has failed its initial signature test, delaying its path to the November ballot. Officials say too many duplicate signatures were found in the sample, forcing a full manual review of all petitions. While it could still qualify, election leaders warn the timeline is now tight, putting the measure’s chances in jeopardy. An Inland Empire family says they were stunned after discovering what appeared to be someone else’s ashes inside an urn they bought on Amazon. The family is now trying to track down the person’s loved ones, but says responses from Amazon and the seller have been slow and frustrating. Please Like, Comment and Follow 'Philip Teresi on KMJ' on all platforms: --- Philip Teresi on KMJ is available on the KMJNOW app, Apple Podcasts, Spotify, YouTube or wherever else you listen to podcasts. -- Philip Teresi on KMJ Weekdays 2-6 PM Pacific on News/Talk 580 AM & 105.9 FM KMJ | Website | Facebook | Instagram | X | Podcast | Amazon | - Everything KMJ KMJNOW App | Podcasts | Facebook | X | Instagram See omnystudio.com/listener for privacy information.

The Underpowered Hour
Range Rover SV Ultra Mega Wellness Floors, JLR Profits Down 99%, and UK Defender Replacement Rumors

The Underpowered Hour

Play Episode Listen Later May 18, 2026 26:41


Steve Beres and Ike Goss kick off the Underpowered Hour by reacting to a Range Rover SV Ultra (and “Ultra Mega”) promo highlighting a 21-speaker electrostatic sound system, haptic “sensory floor,” and wellness modes that spark jokes about cost, recalls, and a 4D in-car experience. They then discuss conflicting Jaguar Land Rover financial headlines, including profits reportedly down 99% due to warranty costs tied to a 170,000-vehicle recall, cyber attacks, Middle East war impacts, and tariffs, though the loss “beat expectations.” Next, they cover the UK Ministry of Defense seeking a classic Defender replacement, with potential bids from Land Rover, the Ineos Grenadier, and other manufacturers, plus rumors of a smaller Ineos EV partnership tied to Chery and the name “Fusilier.” Ike recaps attending Oregon's Rover Rendezvous in a 1957 Series I 107 station wagon, including minor repairs and a failed voltage regulator, and they close with upcoming guests and Steve's excitement about a Dutch Bros opening in Valencia.00:00 Show Intro and Hosts01:20 SV Ultra Mega Tease02:59 Electrostatic Audio Demo05:22 Wellness Modes Mockups07:50 4D Haptics and Price Jokes09:12 JLR Profits and Recalls11:04 MOD Defender Replacement Race13:28 Military Needs vs New Defender14:32 Who Will Build It15:07 Tiny Grenadier Rumors16:18 Chery Partnership Speculation17:08 Fusilier Name Reveal18:12 Tranquility Mode Banter18:47 Oregon Rover Rendezvous19:55 107 Wagon Road Trip Fixes20:59 Event Trucks and Activities21:53 Anarch 80th Planning22:47 JB Weld Head Gasket Saga24:14 Bad Repairs Philosophy25:29 Next Week and Dutch Bros27:03 Signing Off

What's Right Show
5.18.26 AI Job Replacement Coming Fast And Unite the Kingdom Protests

What's Right Show

Play Episode Listen Later May 18, 2026 40:42


Today on What's Right:Citadel CEO on AI replacing white collar workersUnite the Kingdom and the West protests in the United KingdomRINO Bill Cassidy soundly defeated in his primaryNew Supreme Court decision on truckingThanks for tuning into today's episode of What's Right! If you enjoyed this episode, subscribe to the show on Spotify or Apple Podcasts, and make sure you leave us a 5-star review.Have personal injury questions? Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sam & Ash Injury Law⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to get free answers 24/7.Connect with us on our socials:TWITTERSam ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@WhatsRightSam⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠What's Right Show ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@WhatsRightShow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠FACEBOOKWhat's Right Show ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/WhatsRightShow/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠INSTAGRAMWhat's Right Show ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@WhatsRightShow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠EMAILSam sam@whatsrightshow.comProducer Robbie robbie@whatsrightshow.comTo request a transcript of this episode, email ⁠⁠marketing@samandashlaw.com

Roofing Road Trips with Heidi
Beyond Replacement: Adding Restoration to Your Service Mix

Roofing Road Trips with Heidi

Play Episode Listen Later May 18, 2026 24:16


In this episode of Roofing Road Trips, Karen Edwards sits down with Mike Feazel of Roof Maxx to discuss his evolution from traditional roofing contractor to restoration brand founder. Mike shares what sparked his pivot from tear-offs to treatments designed to extend shingle life and explains how restoration complements replacement and routine maintenance. The conversation explores how contractors can position restoration within their service mix, the environmental advantages of reducing landfill waste and the realities behind common myths about performance, durability and long-term value for both contractors and homeowners.  Learn more at RoofersCoffeeShop.com!  https://www.rooferscoffeeshop.com/   Are you a contractor looking for resources? Become an R-Club Member today! https://www.rooferscoffeeshop.com/rcs-club-sign-up   Sign up for the Week in Roofing!  https://www.rooferscoffeeshop.com/sign-up   Learn more about (Roof Maxx) here! (https://www.rooferscoffeeshop.com/directory/roof-maxx)  Follow Us!   https://www.facebook.com/rooferscoffeeshop/  https://www.linkedin.com/company/rooferscoffeeshop-com  https://x.com/RoofCoffeeShop  https://www.instagram.com/rooferscoffeeshop/  https://www.youtube.com/channel/UCAQTC5U3FL9M-_wcRiEEyvw  https://www.pinterest.com/rcscom/  https://www.tiktok.com/@rooferscoffeeshop  https://www.rooferscoffeeshop.com/rss  #RoofersCoffeeShop #MetalCoffeeShop #AskARoofer #CoatingsCoffeeShop #RoofingProfessionals #RoofingContractors #RoofingIndustry 

A to Z Sports Nashville
PRIMETIME: Titans selection of Coach Mac replacement starts controversy among alumni and fans

A to Z Sports Nashville

Play Episode Listen Later May 18, 2026 14:17


PRIMETIME: Titans selection of Coach Mac replacement starts controversy among alumni and fans For More PRIMETIME coverage follow us here: www.atozsports.com/nashville Podcasts: atozsports.com/podcasts Facebook: https://www.facebook.com/atozsportsnashville  Instagram: https://www.instagram.com/atozsports/  Twitter: https://twitter.com/AtoZSports  TikTok: https://www.tiktok.com/@atozsportsnashville #AtoZSports #TennesseeTitans #NFLFootball #Titans #NFLUpdates #NFLFootball Learn more about your ad choices. Visit megaphone.fm/adchoices

Pawlik Automotive Podcast
2012 Jeep Wrangler Tie Rod Replacement

Pawlik Automotive Podcast

Play Episode Listen Later May 18, 2026 5:43


Gaslamp Ball: for San Diego Padres fans
PADS ABOVE REPLACEMENT: Canning and Giolito Deep Dive

Gaslamp Ball: for San Diego Padres fans

Play Episode Listen Later May 17, 2026 66:23 Transcription Available


John and Raphie are back dig deep on the Padres new (checks notes) #3 and #4 starters? Lucas Giolito and Griffin Canning are here, so the boys break down what we may be able to expect them from going forward.Want to get this show and tons of others early and ad-free? Plus access to post game shows, our vaunted PHT Discord server and more? Become a patron at patreon.com/padreshottub

DOCS TALK SHOP
35. Hormones Reconsidered: What We Got Wrong About Estrogen, Risk, and Replacement

DOCS TALK SHOP

Play Episode Listen Later May 17, 2026 51:17 Transcription Available


In this episode, we're joined by Debra Zaslow—author and storyteller—who shares her personal experience with hormone replacement therapy, including some immediate and unexpected effects that took her by surprise.From that starting point, we explore several unexpected ideas: Estrogen alone may reduce breast cancer risk in certain groups  Not all “progesterone” is the same—synthetic versions can behave very differently  The way a hormone is delivered (pill vs patch vs topical) can significantly change its effects  Hormones are often prescribed without measuring levels—unlike almost every other hormone in medicine  Many key hormones, including estrogen and testosterone, are made from cholesterol Dr. Deborah Gordon and I revisit hormone therapy in response to your strong interest in the topic. The conversation moves from lived experience to clinical nuance—how different formulations behave, why dosing and monitoring matter, and how to think more precisely about risks and benefits, especially in menopause and in more complex settings like cancer history.A candid, grounded discussion for anyone trying to make sense of hormones beyond the headlines.Dawn Lemanne, MD Oregon Integrative OncologyLeave no stone unturned.Deborah Gordon, MDNorthwest Wellness and Memory CenterBuilding Healthy Brains

RNZ: Morning Report
Teachers raise concerns over NCEA replacement

RNZ: Morning Report

Play Episode Listen Later May 17, 2026 5:28


Education Minister Erica Stanford has confirmed the qualifications that will replace NCEA from 2028. President of the New Zealand Association for the Teaching of English, Pip Tinning spoke to Ingrid Hipkiss.

Krishna's Mercy
The One With The Expensive Replacement

Krishna's Mercy

Play Episode Listen Later May 17, 2026 8:08


“O son of Kunti [Arjuna], I am the taste of water, the light of the sun and the moon, the syllable om in the Vedic mantras; I am the sound in ether and ability in man.” (Lord Krishna, Bhagavad-gita, 7.8)

An Evening At the Movies
An Evening With Some Replacement Killers

An Evening At the Movies

Play Episode Listen Later May 15, 2026 90:41


We are a couple weeks early but as we continue Martial Arts Month we also are celebrating the birth of the great Chris "Papa Palpatine" Cole. Join Kasey, Amanda, and Chris as we give our colorful thoughts on The Replacement Killers

The Redmen TV - Liverpool FC Podcast
A new name linked as a potential Salah Replacement | Redmen Bitesize

The Redmen TV - Liverpool FC Podcast

Play Episode Listen Later May 14, 2026 10:55


We've got a new name linked as a possible Salah replacement in Hoffenheim's Bazoumana Touré as well as Diomande speaking with reporters about his future. There's also a host of fitness updates ahead of Villa and some conflicting Alonso reports. Hosted on Acast. See acast.com/privacy for more information.

Extinction Rebellion Podcast
News from a World in Flux Ep. 33: The true cost of AI and a COP replacement?

Extinction Rebellion Podcast

Play Episode Listen Later May 14, 2026 44:45


Extinction Rebellion's co-founder Clare Farrell and conservation scientist Dr Charlie Gardner team up once more to discuss issues and stories they feel are not getting enough airtime. They want to make sure that the latest news in science and important reports that are relevant to the climate and ecological crisis are flagged and explained in ways that are easy to understand.EPISODE 33: The true cost of AI and a COP replacement?In this episode, Clare and Charlie discuss the first Just Transition Away from Fossil Fuels conference held in Santa Marta Colombia in April 2026. They also look at what data centres and a booming AI industry means for the environment and beyond.REFERENCESJust Transition Away from Fossil Fuels Conferencehttps://transitionawayconference.com/Key Outcomes from Santa Marta - Carbon Briefhttps://www.carbonbrief.org/santa-marta-key-outcomes-from-first-summit-on-transitioning-away-from-fossil-fuels/The AI Climate Hoax Reporthttps://drive.google.com/file/d/12l1W4W25b-_ff6yFNJABkfal9_9oevxe/viewNew datacentres risk doubling Great Britain's electricity use - Guardianhttps://www.theguardian.com/technology/2026/feb/23/new-datacentres-risk-doubling-uk-electricity-use-ofgem-peak-demandUK departments at odds over energy demands of AI datacentres - Guardianhttps://www.theguardian.com/technology/2026/apr/26/uk-departments-at-odds-over-energy-demands-of-ai-datacentres The Thermodynamic Endgame of Industrial Civilizationhttps://kasperbenjamin.substack.com/p/the-thermodynamic-endgame-of-industrial Data Centre Watch report https://www.datacenterwatch.org/report---------------------Please, share, comment, subscribe, like, mobilise, and donate!https://ko-fi.com/worldinflux 

Telecom Reseller
Purpose-Built Hardware: TELCLOUD Shows the Devices Behind Reliable POTS Replacement, POTS and Shots Podcast Series

Telecom Reseller

Play Episode Listen Later May 14, 2026


“These are purpose-built devices,” says Jake Jacoby, CEO of TELCLOUD. “They're UL listed, certified, tested, and designed specifically for this business.” In the latest episode of the TELCLOUD POTS and Shots Podcast Series, Doug Green, Publisher of Technology Reseller News, speaks with Jacoby about the hardware that makes modern POTS replacement possible. Jacoby showcases two TELCLOUD devices: the POTScast 8 LTE PC228 LTE, which supports eight analog lines, and the POTScast 2 LTE PC222 LTE, which supports two. Both are designed to support legacy and life-safety systems such as elevators, fire alarms, security systems, fax lines, SCADA applications, modems, and emergency phones as copper lines are phased out. The POTScast platform combines analog support with modern LTE and WAN connectivity, including broadband, Wi-Fi as WAN, satellite, and cellular. Each device includes 24-hour battery backup, helping ensure that critical communications continue even when building power fails. Jacoby also explains TELCLOUD's modular design. Because cellular signal is often weak inside telecom rooms, TELCLOUD supports Power over Ethernet, allowing routers from partners such as Ericsson, Peplink, Digi, InHand, ATEL, and Seego to be placed up to 250 feet away for better reception. The episode closes with the Shots segment, featuring Herencia Historico Grand Reserve Extra Añejo, a five-year-aged, small-batch tequila from Jalisco presented in a distinctive handcrafted bottle. For more information, visit telcloud.com or call 844-900-2270.

Eschatology Matters
Does “All Israel Will Be Saved” Mean What You Think? (Romans 11)

Eschatology Matters

Play Episode Listen Later May 13, 2026 9:18 Transcription Available


What does the Bible actually teach about the future of Israel—and have we been reading Romans 11 wrong?In this episode, we challenge the common assumptions around “all Israel will be saved” and unpack a view deeply rooted in church history that most Christians rarely hear. Instead of a future defined by endless conflict, Scripture points to something far bigger—and far more hopeful.You'll discover: What Paul really means in Romans 11Whether “replacement theology” is a misunderstandingIf God's promises to Israel are physical, spiritual, or bothHow the New Testament defines the true people of GodThis isn't about speculation—it's about reading the Bible on its own terms.

The Health Courage Collective
254: Melatonin During Perimenopause

The Health Courage Collective

Play Episode Listen Later May 13, 2026 28:08 Transcription Available


How confident are you in choosing the right dose and right form of melatonin to optimize your health in your 40s and 50s?  Our natural production of melatonin decreases with age and with declining sex hormone levels.  And it affects more than just your sleep.  So is it something you should be taking?  And how much should you take and how often should you take it?   www.healthcouragecollective.comAre you ready to give your cells their best chance to not have to stop living before they die by allowing them access to physiologic levels of hormones, but aren't sure how to even get started?  Join the waitlist for my new beta program here and help me figure out how best to help wonderful women like you get the hormone care they deserve!Join the Waitlist HereCome visit me: www.healthcouragecollective.comemail me: healthcouragecollective@gmail.com

Health Marketing Collective
Trust Is Built in Experience, Not Messaging

Health Marketing Collective

Play Episode Listen Later May 13, 2026 36:44 Transcription Available


Welcome to the Health Marketing Collective, where strong leadership meets marketing excellence.In today's episode, we delve into the barriers to technology adoption among older, higher-risk populations and how innovative companies are reframing the narrative around “tech hesitancy” in healthcare. Joining us is Harry DiFrancesco, CEO and co-founder of Carda Health, who brings real-world insights from building virtual cardiac and pulmonary rehab programs designed to meet patients where they are, especially those traditionally underserved by hospital-based care.After caring for his own parents and seeing firsthand the challenges of accessing rehabilitation in rural America, Harry founded Carda Health with a personal mission: to make advanced, supportive care available at home for those who need it most. In a landscape awash in new technology and AI-driven solutions, Harry DiFrancesco argues that trust more than tools or tactics is the critical factor for patient engagement and health outcomes.In this conversation, Sara and Harry unpack common misconceptions about seniors and technology, discuss the real sources of adoption friction (it's not what most people think), and share best practices for designing tech-enabled healthcare that earns genuine trust. They also explore the right and wrong ways to leverage AI in healthcare, emphasizing that technology must enhance value and human connection to truly succeed.Thank you for joining the Health Marketing Collective, where we explore the leadership and marketing strategies shaping the future of healthcare.Key Takeaways:Challenging the "Tech Hesitant Senior" Narrative: Harry DiFrancesco pushes back against the widespread assumption that older adults simply can't or won't use technology. Instead, he highlights that tens of thousands of seniors engage daily with Carda Health's virtual rehab solutions, proving it's a matter of design and support not innate reluctance. The true barrier is that most tech is built for younger users, not that older users lack the capability or willingness.Designing With Empathy and Intentionality: Success with older populations requires adapting design choices to meet their needs: larger fonts, simple navigation, and reducing unnecessary complexity (like having apps pre-downloaded and minimizing device setup). Harry DiFrancesco emphasizes listening to end-users, removing friction, and maintaining a deeply empathetic mindset leveraging staff who are trained to step in and help when human intervention is needed to overcome anxiety or confusion.Trust Is Earned Through Value and Transparency: Trust, especially in healthcare, hinges on communicating clear, relatable value and maintaining transparency, particularly around costs. Carda Health works to advocate for fee waivers, proactively communicates about copays, and offers price estimates upfront, knowing that unexpected bills quickly erode confidence and engagement. Brands must ensure their users feel informed and see immediate benefits from participation.AI as an Efficiency Layer (Not a Replacement for Care): Harry shares a realistic perspective on AI in health: it should support clinicians, improve efficiency, and free up time for meaningful patient relationships not replace human care. He critiques Silicon Valley's fear-driven AI messaging, suggesting it breeds mistrust. At Carda Health, AI is used for device monitoring, automating coverage decisions, and relieving clinicians of administrative burdens, enabling them to focus on patient connection.A “Locus of Control” Mindset Drives Adoption: Rather than blaming patients for non-adoption, Harry advocates for companies to internalize what they can change about their own products and processes to remove barriers. The fundamental adoption driver isn't age or skepticism; it's whether the product delivers more value than friction. Companies that actively seek out, understand, and refine the factors contributing to user anxiety or hesitation can win trust and long-term engagement.Thank you for being part of the Health Marketing Collective, where strong leadership meets marketing excellence. The future of healthcare depends on it.Mentioned in this episode:Health Marketing Collective is Powered by InprelaThe Health Marketing Collective is powered by Inprela: a communications firm built for health brands determined to lead, not follow. We partner with marketing innovators who aren't just chasing attention—they're building movements. Connect with the audiences shaping the future of care and lead the conversations that move your market. Ready to rise above the noise? Visit inprela.com. Let's create something that moves the market.Inprela Communications

WBBM Newsradio's 4:30PM News To Go
Aldermen get few answers on ShotSpotter replacement search

WBBM Newsradio's 4:30PM News To Go

Play Episode Listen Later May 12, 2026 0:57


WBBM political editor Geoff Buchholz reports on a Chicago City Council hearing dealing with the effort to find a replacement for the "ShotSpotter" gunshot detection system.

Nailing The Apex with Tim Hauraney
Is Oscar Pisatri, Max Verstappen's replacement? + Engine changes coming in 2027 | May 11th, 2026

Nailing The Apex with Tim Hauraney

Play Episode Listen Later May 11, 2026 48:05


On this episode of Nailing the Apex Adam Wylde and Tim Hauraney discuss regulation changes coming to the engines in 2027, Bio-Fuels and if Red Bull Racing is looking at signing Oscar Piastri. 00:00 Engine regulation changes coming in 2027 14:27 The conversation around Bio-Fuels 28:47 Is Red Bull after Oscar Piastri? Follow Nailing the Apex on TikTok, Instagram and Youtube! Instagram - @nailingtheapex TikTok - @nailingtheapex Youtube - @NTAPod Follow Tim Hauraney on Twitter / X: @TimHauraney Follow Adam Wylde on Twitter / X: @AdamWylde Visit https://sdpn.ca for merch and more. Follow us on Twitter (X): @sdpnsports Follow us on Instagram: @sdpnsports For general inquiries, email: info@sdpn.ca Learn more about your ad choices. Visit megaphone.fm/adchoices

The Leadership Boost
Succession is NOT Replacement

The Leadership Boost

Play Episode Listen Later May 11, 2026 16:14


Here's what the replacement mindset produces.You identify someone who looks like you. Leads like you. Thinks like you. Has navigated the organisation the way you have.You develop them to fill the seat you currently occupy.And then one day they step into it — and discover that the seat has changed. The organisation has moved. The challenges are different. The market has shifted. The team has new faces and new dynamics.And the person you prepared — perfectly — for the organisation as it was, is now leading the organisation as it is. Without the preparation that required.

Empowered Patient Podcast
Enzyme Replacement Therapy for Sanfilippo Syndrome Type B with Dr. Javier Szwarcberg Spruce Biosciences

Empowered Patient Podcast

Play Episode Listen Later May 11, 2026 20:42


Dr. Javier Szwarcberg, CEO of Spruce Biosciences,  is developing drugs for rare diseases with a primary focus on Sanfilippo Syndrome Type B, a devastating genetic neurodegenerative disease affecting children.  The source of this condition is a lack of an enzyme, which results in a buildup of a toxic substance in the brain.  The company's drug is an enzyme replacement therapy administered directly to the brain to bypass the blood-brain barrier, and clinical trial data is showing a strong effect on the toxic substrate in the brain and a meaningful benefit on cognition. Javier explains, "It's a devastating, profoundly affecting disease whereby children are typically born normally and born asymptomatic. And over time, they develop an accumulation of a toxic substrate throughout the body, but primarily the brain. And because of that, it eventually results in a fairly young age, usually between two and a half and I would say three and a half, in symptoms starting. That toxic substance builds in throughout the brain and starts affecting initially learning behavior. Sleep patterns are very much affected, whereby children don't sleep at night and sleep during the day, and they're very hyperactive. And sometimes the diagnosis is confused, and there's no clarity as to what is going on with the child, early in the onset of the disease."   "Yes, it's a genetic disease that's inherited. There's a missing enzyme responsible for the metabolism of this toxic substrate, which I talked about, called heparan sulfate. So when heparan sulfate builds up in the brain, it causes inflammation and neurotoxicity, ultimately resulting in neurodegeneration. Think about it as a disease that is very similar to what you end up seeing with Alzheimer's, whereby the toxic substrate in Alzheimer's is between neurons and outside of the actual cell. In this case, in this disease, the toxic substance, which is different than the one that accumulates in Alzheimer's but builds within the neural cells. Yes, so that's very well-known and very well-characterized." #SpruceBio #SanfilippoSyndrome #MPSIIIB #CureSanfilippo #RareDiseases #EnzymeReplacementTherapy #LysosomalStorageDisorders #BiopharmaceuticalInnovation #ClinicalTrials #RareDiseaseResearch #HealthcareInnovation #PrecisionMedicine sprucebio.com Download the transcript here

Empowered Patient Podcast
Enzyme Replacement Therapy for Sanfilippo Syndrome Type B with Dr. Javier Szwarcberg Spruce Biosciences TRANSCRIPT

Empowered Patient Podcast

Play Episode Listen Later May 11, 2026


Dr. Javier Szwarcberg, CEO of Spruce Biosciences,  is developing drugs for rare diseases with a primary focus on Sanfilippo Syndrome Type B, a devastating genetic neurodegenerative disease affecting children.  The source of this condition is a lack of an enzyme, which results in a buildup of a toxic substance in the brain.  The company's drug is an enzyme replacement therapy administered directly to the brain to bypass the blood-brain barrier, and clinical trial data is showing a strong effect on the toxic substrate in the brain and a meaningful benefit on cognition. Javier explains, "It's a devastating, profoundly affecting disease whereby children are typically born normally and born asymptomatic. And over time, they develop an accumulation of a toxic substrate throughout the body, but primarily the brain. And because of that, it eventually results in a fairly young age, usually between two and a half and I would say three and a half, in symptoms starting. That toxic substance builds in throughout the brain and starts affecting initially learning behavior. Sleep patterns are very much affected, whereby children don't sleep at night and sleep during the day, and they're very hyperactive. And sometimes the diagnosis is confused, and there's no clarity as to what is going on with the child, early in the onset of the disease."   "Yes, it's a genetic disease that's inherited. There's a missing enzyme responsible for the metabolism of this toxic substrate, which I talked about, called heparan sulfate. So when heparan sulfate builds up in the brain, it causes inflammation and neurotoxicity, ultimately resulting in neurodegeneration. Think about it as a disease that is very similar to what you end up seeing with Alzheimer's, whereby the toxic substrate in Alzheimer's is between neurons and outside of the actual cell. In this case, in this disease, the toxic substance, which is different than the one that accumulates in Alzheimer's but builds within the neural cells. Yes, so that's very well-known and very well-characterized." #SpruceBio #SanfilippoSyndrome #MPSIIIB #CureSanfilippo #RareDiseases #EnzymeReplacementTherapy #LysosomalStorageDisorders #BiopharmaceuticalInnovation #ClinicalTrials #RareDiseaseResearch #HealthcareInnovation #PrecisionMedicine sprucebio.com Listen to the podcast here

Morning Drive
688: Hour 2: Vrabel Impact on Patriots; Brinker Replacement; Rex Rant (5-8-26)

Morning Drive

Play Episode Listen Later May 8, 2026 40:53


There was some new context involving Mike Vrabel and Dianna Russini this week.  How much could this affect the Patriots on the field this upcoming season?  Is there a situation where the league would need to get involved?  How much of a distraction is this for the Patriots?  Do we think the Titans will try to hire someone to replace Chad Brinker?  Joe has the Rex Rant to close the hour.

The Opperman Report
Plastic Macca: The Secret Death and Replacement of Beatle Paul McCartney

The Opperman Report

Play Episode Listen Later May 6, 2026 60:07 Transcription Available


Plastic Macca: The Secret Death and Replacement of Beatle Paul McCartneyIn the fall of 1969, a rumor swept across two continents that the lovable Beatle, Paul McCartney, had been killed in a car crash. According to some, he was replaced by “Billy Shears.” This book is an attempt to separate fact from fiction. Join the author on a fascinating trip deep into rock n' roll lore. You will no doubt be surprised by some of the discoveries that are made along the way to the shocking conclusion. This book will rock your world!https://amzn.to/4sHsAX6Become a supporter of this podcast: https://www.spreaker.com/podcast/the-opperman-report--1198501/support.

The Midday Show
What would a movie about replacement officials look like?

The Midday Show

Play Episode Listen Later May 6, 2026 16:26


Ask Me Anything and takeaways of the day featuring Andy, Randy, Beau, and Abe.

MPR News Update
Minnesota lead pipe replacement

MPR News Update

Play Episode Listen Later May 6, 2026 4:30


A Minnesota man who spent years in prison before his conviction for first-degree murder was vacated in 2023 may now receive several million dollars from the state. A judge found that faulty witness testimony was used in convicting Marvin Haynes for the 2004 killing of Harry Randy Sherer in Minneapolis.And local leaders and labor unions are urging Minnesota lawmakers to prioritize lead pipe replacement this year.Those stories and more in today's evening update from MPR News. Hosted by Emily Reese. Music by Gary Meister.

BRAINZ PODCAST
From Replacement to Regeneration – Brainz Podcast with Professor Paul Lee

BRAINZ PODCAST

Play Episode Listen Later May 6, 2026 24:01


From Replacement to Regeneration – Brainz Podcast with Professor Paul LeeProfessor Paul Lee, orthopedic surgeon and specialist in regenerative medicine, joins the Brainz Magazine podcast for a powerful conversation on joint health, cartilage, and the future of regeneration in modern medicine.In this episode, he challenges the common belief that cartilage cannot heal, explaining why regeneration is not only possible but often overlooked before patients are guided toward joint replacement. Drawing from over 20 years of clinical experience, Paul shares a new perspective on preserving function and intervening earlier. The conversation explores the science behind cartilage, the role of the wider musculoskeletal system, and how engineering, medicine, and innovation come together in his work. Paul also breaks down the difference between real regenerative medicine and hype, and what patients should be aware of when navigating this rapidly growing space. This is an insightful and practical episode for anyone interested in long-term joint health, prevention, and what's truly possible before replacement becomes the default path.With podcast host Miceal O´KaneHope you'll enjoy the episode! Hosted on Acast. See acast.com/privacy for more information.

Le Batard & Friends - STUpodity
Set 1: Replacement Bananas

Le Batard & Friends - STUpodity

Play Episode Listen Later May 4, 2026 45:53 Transcription Available


Stugotz and the crew discuss the Celtics blowing a 3–1 lead and question whether they should blow up the team. Izzy believes the Knicks/76ers series is the most exciting second-round matchup. Then it’s time for Stugotz’s “We Can” observations. Taylor claims Anne Hathaway is on the “Still Got It” First Team. Stugotz believes women might have saved horse racing after the Kentucky Derby. Is the Savannah Bananas’ owner exploiting his team? Who is the Aaron Judge of the Savannah Bananas? See omnystudio.com/listener for privacy information.

The Redmen TV - Liverpool FC Podcast
Mo Salah's REPLACEMENT Should Be... | Man United v Liverpool DEBATE

The Redmen TV - Liverpool FC Podcast

Play Episode Listen Later Apr 29, 2026 30:05


Ste is joined by Paul and Abi as they debate the hottest topics ahead of Liverpool's clash with North West rivals Manchester United at Old Trafford in the Premier League.

Breaking Points with Krystal and Saagar
4/17/26: Iran OPENS STRAIT, Zohran Triggers Billionaire Crashout, College Grad Unemployment Apocalypse, AOC Flamed On Pelosi Replacement

Breaking Points with Krystal and Saagar

Play Episode Listen Later Apr 17, 2026 91:44 Transcription Available


The BP team looks at Iran opening the Strait of Hormuz in ceasefire agreement, Zohran triggering the rich in new Tax Video, and AOC giving a stumbling answer to a Drop Site reporter on who will replace Pelosi in California race. To become a Breaking Points Premium Member and watch/listen to the show AD FREE, uncut and 1 hour early visit: www.breakingpoints.comMerch Store: https://shop.breakingpoints.com/See omnystudio.com/listener for privacy information.