Primary Care Today

Host: Jennifer Caudle, DO Guest: Victoria A. Statler, MD, MSc Test-confirmed influenza outcomes provide a specific measure of influenza vaccine effectiveness (VE) and has helped to illustrate the potential benefit of cell-based versus egg-based vaccines.1 So what data support improved VE from cell-based flu vaccines versus egg-based vaccines? To learn more, join Dr. Jennifer Caudle as she speaks with Dr. Victoria A. Statler, Associate Professor of Pediatrics at the University of Louisville and the Director of the Pediatric Transplant and Immunocompromised Host service at Norton Children's Hospital. Reference: Stein AN, Mills C, McGovern, et al. Superior effectiveness of cell-based versus egg-based quadrivalent influenza vaccines against test-confirmed influenza over three consecutive seasons in the United States. Paper presented at: The Ninth European Scientific Working Group Influenza (ESWI) Influenza Conference; September 17-20, 2023: Valencia, Spain. USA-QIVc-23-0119 01/24

Guess what? The CDC's Advisory Committee on Immunization Practices had a unanimous vote in favor of a preferential recommendation of vaccines for the cool adults who are 65 and older—one of these options is adjuvanted influenza vaccines.1 Talk about a milestone in the world of public health! Now the burning question is why on earth did they decide on adjuvant vaccines? Let's unravel this immunization mystery together, shall we? Reference: Grohskopf LA, Blanton LH, Ferdinands JM, Chung JR, Broder KR, Talbot HK, Morgan RL, Fry AM. Prevention and control of seasonal influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices - United States, 2022-23 influenza season. MMWR Recomm Rep. 2022 Aug 26;71(1):1-28. doi: 10.15585/mmwr.rr7101a1 USA-CRP-23-0037 12/23

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Wendy Wright, DNP Guest: Elias Chahine, PharmD, FCCP, FASCP While the flu may seem benign to some, it may result in up to 710,000 hospitalizations and up to 52,000 deaths every year.1 So how are current and concerning trends in declining flu vaccinations being addressed? To hear the latest updates and recommendations, join Dr. Charles Turck as he speaks with Dr. Wendy Wright, Owner and Family Nurse Practitioner at Wright & Associates Family Healthcare in New Hampshire, and Dr. Elias Chahine, Professor of Pharmacy Practice at Palm Beach Atlantic University in West Palm Beach, Florida and Clinical Pharmacy Specialist at Wellington Regional Medical Center. Reference: Disease Burden of Influenza. Centers for Disease Control and Prevention. https://www.cdc.gov/flu/about/burden/index.html. Updated October 4, 2022. Accessed November 28, 2023. USA-CRP-23-0043 01/24

Several factors impact vaccine effectiveness from year to year. One of them is the phenomenon of strain mismatch which may result from egg adaptation during the egg-based influenza vaccine manufacturing process.1 So what exactly is the process of egg-adaptation? Gather your esteemed colleagues from far and wide, and tune into this episode of World of Tomorrow to learn more. Reference: Rajaram S, Boikos C, Gelone DK, Gandhi A. Influenza vaccines: the potential benefits of cell-culture isolation and manufacturing. Ther Adv Vaccines Immunother. 2020;8:1-10. USA-CRP-23-0021 11/23

Host: Joyce Riley Guest: Lance Sloan, MD Pneumococcal vaccination isn't restricted to a specific season. Patients can get vaccinated with Prevnar 20 at any time. Clinicians can help their patients better understand the importance of pneumococcal vaccination. Join Joyce Riley as she gets expert insights from Dr. Lance Sloan, Endocrinologist, Nephrologist, and Metabolist in Lufkin, Texas. Continuing medical education credits are not available for this program.© 2023 Pfizer Inc. All rights reserved. PP-PRV-USA-0378

Host: Marc E. Agronin, MD Guest: Richard S. Isaacson, MD TBD

Host: Marc E. Agronin, MD Guest: Richard S. Isaacson, MD TBD

Guest: Marc E. Agronin, MD TBD

Host: Marc E. Agronin, MD Guest: Richard S. Isaacson, MD TBD

Host: Marc E. Agronin, MD Guest: Richard S. Isaacson, MD TBD

Host: Marc E. Agronin, MD Guest: Richard S. Isaacson, MD TBD

Host: Marc E. Agronin, MD Guest: Richard S. Isaacson, MD TBD

Guest: Marc E. Agronin, MD TBD

Host: Sara W. Koblitz Guest: Michael J. Thorpy, MD While most clinicians are aware of a drug being either “approved” or “not approved” by the FDA, many are not familiar with the term “tentative approval.” Leading experts, attorney Sara Koblitz, JD, and Dr. Michael Thorpy, review the FDA approval process, explore how “tentative approval” is currently impacting treatment in the field of sleep medicine, and discuss how “non-drug” issues are related to delayed FDA approval. Review the latest safety and efficacy pivotal trial data associated with once-nightly sodium oxybate and find out if we're truly on the cusp of a new awakening in sleep medicine.

Host: Marc E. Agronin, MD Guest: Richard S. Isaacson, MD TBD

Host: Marc E. Agronin, MD Guest: Richard S. Isaacson, MD TBD

Host: Charles P. Vega, MD Guest: Alvaro E. Galvis, MD, PhD How does a patient's culture impact their health behaviors? Find clues in a case highlighting how cultural responsiveness leads to open patient-clinician communication that is the cornerstone of good clinical care. Listen in as 2 leading experts address disparities by breaking down barriers and building better communication with Latino patients. Will you evolve your clinical approach by taking the necessary (easy) steps to help overcome medical mistrust?

Host: Charles P. Vega, MD Guest: Kareen Y. Espino, MD What is cultural humility, and how can it be incorporated into clinical practice? How does a patient's culture impact their health behaviors, and why does your own culture and your “practice” approach matter? Listen in as 2 leading experts navigate concerns surrounding cultural humility and emphasize the importance of empathy while they review tips for improved communication with Latino patients. There are easy ways to integrate small but meaningful changes into your clinical practice to help bridge communication gaps and enable your patients to live healthier lives.

Host: Charles P. Vega, MD Guest: Alejandra Hurtado National trends highlight the necessity of a diverse workforce that can better meet the needs of underserved Latino communities. Hear about the real impact being made by training programs designed to meet community needs through the eyes of a medical student as she discusses her cultural background and future aspirations to give back to the health of her community. Will you be inspired to offer mentorship opportunities and diversify your staff to provide culturally appropriate care?

Guest: John Friedewald, MD What did the first day of the American Society of Nephrology's Kidney Week 2021 showcase? From COVID-19 to developments in kidney disease, Dr. John Friedewald, Professor of Medicine and Surgery at the Northwestern University Feinberg School of Medicine, shares highlights from Day 1.

Host: Charles P. Vega, MD Guest: Candice Taylor Lucas, MD, MPH, FAAP What is cultural humility, and how can it be incorporated into clinical practice? How does your patient's culture impact their health behaviors, and why does your culture matter? Listen in as two leading experts navigate concerns surrounding cultural humility and emphasize the importance of empathy, awareness, and advocacy. Discover ways to integrate small but important changes into your clinical practice to help bridge communication gaps and enable your patients to thrive.

Host: Charles P. Vega, MD Guest: Lionel Phillips, MBA Learn why diversity in clinical trials is so important to community health. Two experts discuss the key role that trusted messengers play in enrollment, why it is critical to break the cycle of medical mistrust, and the downstream effect of a lack of diversity in clinical trials.

Host: Charles P. Vega, MD Guest: Robert O. Roswell, MD, FACC, FACP Diversifying our physician workforce so that it is more racially, ethnically, and geographically balanced can ultimately have a positive impact on community health. Join us as two experts discuss how pipeline programs reaching children as early as elementary school can help ensure workplace diversity. Also find out how clinicians can be advocates for their patients by helping to disentangle them from structural inequities and working towards policy changes. There's a lot than can be done to provide more balanced care, but we need to look beyond simple fixes to the root causes of the issues. So find your bandwidth – that's what you can do today – and discover why it's so important to move upstream to solve the problems manifesting downstream.

Host: Charles P. Vega, MD Guest: Sateria Venable Regional healthcare disparities are biases that are based on where people live. Are your patients' treatment options being impacted and limited by their geographical location? Join us as our two experts discuss how to support broader policy issues and highlight the importance of diagnostic algorithms that have been developed with diverse input. These steps may be of value in your clinical practice to ensure all patients have equal access to care regardless of their epidemiologic, socioeconomic, or insurance circumstances.

Host: Ricardo Franco, MD Guest: Charles P. Vega, MD Armed with Centers for Disease Control and Prevention (CDC) guidelines for HCV universal screening and risk-based testing — and an understanding of the simplicity of prescribing and managing direct-acting antiviral (DAA) therapies — primary care providers (PCPs) will be well equipped to step up and provide comprehensive HCV care and cure. This educational activity offers practical tips and tactics to prepare PCPs for their central role in eliminating HCV.

Host: Matt Birnholz, MD Guest: Gary Cohen, MD What’s the difference between a generic drug and biosimilar? How does the FDA define biosimilarity? And how are biosimilars developed? Get answers to these and other questions with Dr. Gary Cohen, Associate Professor of Oncology at John’s Hopkins School of Medicine and Emeritus Director of the Sandra and Malcolm Berman Cancer Institute at GBMC, in the first episode of this two-part video. ©2020 Amgen Inc. All rights reserved. USA-CBU-80726 10/20

Host: Matt Birnholz, MD Guest: Gary Cohen, MD Biosimilars undergo a rigorous evaluation process to ensure high quality and no clinically meaningful difference between biosimilars and the reference product. To learn more about how biosimilar clinical trials are designed to confirm biosimilarity, tune in to the second episode of this two-part series featuring Dr. Gary Cohen, Associate Professor of Oncology at John’s Hopkins School of Medicine and Emeritus Director of the Sandra and Malcolm Berman Cancer Institute at GBMC. ©2020 Amgen Inc. All rights reserved. USA-CBU-80729 10/20

Host: Matt Birnholz, MD Guest: Jessica Ailani, MD What should you do if a patient uses a prescribed medication and experiences an adverse event? Here to walk us through what clinicians need to keep in mind when detecting and reporting adverse events is Dr. Jessica Ailani, Vice Chair of Strategic Planning in Medstar Georgetown Department of Neurology at Medstar Georgetown University Hospital in Washington, DC. USA-334-83979

Host: Jennifer Caudle, DO Guest: Peter McAllister, MD While both small molecule drugs and monoclonal antibodies are considered targeted therapies, they each have unique characteristics that may influence how they’re used to treat diseases. That’s why Dr. Peter McAllister is here to explain how these two modalities differ in terms of structure, administration routes, and distribution. USA-334-83595

Guest: Jennifer Caudle, DO It’s an unfortunate reality that an increasing number of patients are refusing to get vaccinated—regardless of whether that’s the recommendation for themselves or their children. But luckily, there are ways you can talk to your patients about this, as Dr. Jennifer Caudle explains.

Host: Brian P. McDonough, MD, FAAFP Guest: Kisma Orbovich Improvement is something we’re all constantly chasing, whether it’s in the form of a promotion, a bigger house, or maybe even an ideal weight. So why do we often fail miserably at these attempts to make our lives better? To get to the bottom of this dilemma, Dr. Brian McDonough is joined by Kisma Orbovich, the CEO of Illumination Academy, to reveal the secret to true success and how gratitude may just be the lifehack we’ve been searching for.

Host: Brian P. McDonough, MD, FAAFP Guest: Cecilia Van Cauwenberghe What was once a sci-fi tale is now a reality, but unlike the aliens and monsters common to this genre, artificial intelligence isn’t something healthcare professionals need to fear. On the contrary, it may just be the key to unlocking new solutions in the pharmaceutical industry, as Dr. Cecilia Van Cauwenberghe explains.

Host: Brian P. McDonough, MD, FAAFP Guest: Teresa Gil, PhD Since about 21 million mothers in America experienced sexual abuse in their childhood, there’s a good chance that some of these women are our patients. So as their physicians, how can we provide them with the best possible care as they continue to cope with the lifelong effects of sexual abuse? That’s what Dr. Brian McDonough explores with Dr. Teresa Gil, author of Women Who Were Sexually Abused as Children: Mothering, Resilience, and Protecting the Next Generation.

Host: Brian P. McDonough, MD, FAAFP Guest: Christopher Spagnuola, MD, FAAOS As with any technology, there are benefits and limitations to the computerization of healthcare. On the plus side, as Dr. Christopher Spagnuola explains, electronic medical records are streamlining communication between medical providers when it comes to prescriptions, and telemedicine is revolutionizing post-op following orthopedic surgery. But there are unfortunately some downsides to this technology as well.

Host: Brian P. McDonough, MD, FAAFP Guest: Jorge Garcia, MD Even though people have gained immunity to the Zika virus in certain parts of the world, Zika outbreaks can—and do—still occur. Tune in as Dr. Jorge Garcia joins Dr. Brian McDonough to discuss the who, what, where, why, and how of the Zika virus, the once headline-dominating epidemic.

Host: Brian P. McDonough, MD, FAAFP Guest: Kenneth Davin Fine, MD Dr. Brian McDonough brings up an age-old question: can listening to music cure your ailments? In an attempt to put this long-lived discussion to rest, Dr. McDonough welcomes Dr. Kenny Fine, a physician-musician of 15 years.

Host: Brian P. McDonough, MD, FAAFP Guest: Patricia (Tia) Powell, MD Since dementia is one of the most common health problems in the United States, it's hard not to know at least one person who is impacted by it. Proof of this is Dr. Tia Powell, who discusses the far-reaching impacts of dementia with Dr. Brian McDonough.

Host: Brian P. McDonough, MD, FAAFP Guest: Daryl Gioffre, DC Are our diets helping or hurting us? To examine the link between your gut and your overall health, Dr. Brian McDonough is joined by nutritionist Daryl Gioffre, who suggests that an unhealthy gut could very well be the root cause of significant health issues.

Host: Brian P. McDonough, MD, FAAFP Guest: David Neagle Is it possible that our environment and experiences have subconsciously programmed our emotional response to the world around us? Joining Dr. Brian McDonough is David Neagle, author of The Millions Within: Tips to Improve Emotional Intelligence, to offer advice on what impacts our emotional intelligence and the changes we can implement to strengthen our own. Produced in cooperation with:

Host: Brian P. McDonough, MD, FAAFP Guest: Martin Lupinetti Guest: Richard Snyder, MD First there was paper, then there were traditional electronic health records…so what’s next? Well, more and more states across the country have been diligently working on the development and implementation of health information exchange, bringing all available information to a single point of care. Join Dr. Brian McDonough as he dives deep into the database with Rich Snyder, Chief Medical Officer of Independence Blue Cross, and Martin Lupinetti, President of HealthShare Exchange.

Host: Brian P. McDonough, MD, FAAFP In the early years of Dr. Robin Miller's career, she found herself writing more prescriptions and spending less time counseling the patients sitting in her exam room. It was then that she realized that something had to change…so she quit her job and began a fellowship in integrated medicine. Dr. Brian McDonough talks with Dr. Miller about her decision to switch her career focus and how her approach to diagnosing and treating patients has evolved.

Host: Brian P. McDonough, MD, FAAFP Guest: Elizabeth Dowdell, PhD, RN FAAN Bullying is an unfortunate reality of the adolescent years. However, the implosion of the internet has created a new digital threat that is faceless and nameless: cyberbullying. Dr. Elizabeth Dowdell uncovers the link between risky online behaviors and their impacts in a discussion with Dr. Brian McDonough.