Podcasts about molecules

Electrically neutral group of two or more atoms

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Best podcasts about molecules

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Latest podcast episodes about molecules

SpaceTime with Stuart Gary | Astronomy, Space & Science News
Enceladus Unveiled: Fresh Discoveries of Organic Chemistry Beneath the Ice

SpaceTime with Stuart Gary | Astronomy, Space & Science News

Play Episode Listen Later Oct 8, 2025 25:05 Transcription Available


In this episode of SpaceTime, we dive into the fascinating findings from Saturn's icy moon Enceladus, discuss delays in the Dream Chaser spaceplane's launch schedule, and celebrate NASA's breakthroughs in laser communications for deep space missions.Enceladus: Unveiling Complex ChemistryRecent discoveries reported in the journal Nature Astronomy reveal that Saturn's moon Enceladus is spewing complex organic molecules from its subsurface ocean. Data collected by the Cassini spacecraft during its mission has unveiled fresh insights into the chemical reactions occurring in this hidden ocean. The presence of organic molecules, including precursors for amino acids, raises the possibility that Enceladus may have once harboured conditions suitable for life. This episode explores how these findings could inform future missions aimed at further investigating Enceladus and its potential habitability.Dream Chaser Spaceplane: A Delay in LaunchSierra Space has announced that their Dream Chaser spaceplane's first free flight demonstration has been pushed back to late 2026. Originally designed as a manned spacecraft, Dream Chaser will now serve as a cargo transport for NASA's Commercial Resupply Services, delivering supplies to the International Space Station. The episode discusses the spaceplane's unique design, its cargo capabilities, and the future of its missions, including plans for a fully operational crewed version.Nasa's Optical Deep Space Laser Communications SuccessNASA's new Optical Deep Space Laser Communications project has surpassed all technical goals, paving the way for high-speed communications for future crewed missions to Mars. The technology, which successfully transmitted data over vast distances, demonstrated data rates comparable to broadband Internet services. This breakthrough enables faster communication for astronauts and could revolutionise data transmission in deep space. Tune in to learn more about the technology behind this ambitious project and its implications for future space exploration.www.spacetimewithstuartgary.com✍️ Episode ReferencesNature Astronomyhttps://www.nature.com/natureastronomyNASA Dream Chaserhttps://www.nasa.gov/dreamchaserNASA Optical Deep Space Laser Communicationshttps://www.nasa.gov/lasercomBecome a supporter of this podcast: https://www.spreaker.com/podcast/spacetime-your-guide-to-space-astronomy--2458531/support.Enceladus: Unveiling Complex ChemistryDream Chaser Spaceplane: A Delay in LaunchNASA's Optical Deep Space Laser Communications Success(00:00) The Dream Chaser spaceplane set for another delay(00:48) Scientists have discovered new complex organic molecules spewing from Saturn's Enceladus(09:41) NASA says new optical Deep Space Laser communications project has exceeded all technical goals(17:29) Around a quarter of all press releases in the United States are probably AI generated(19:23) Companies failing to secure AI agents is causing security risks, warns expert(20:27) Gary Stuart says AI agents can be hacked and should be treated like humans

Emergency Medical Minute
Episode 977: Amyloid Therapy and Stroke-like Events

Emergency Medical Minute

Play Episode Listen Later Oct 6, 2025 3:03


Contributor: Aaron Lessen, MD Educational Pearls: The cause of Alzheimer's disease is multifactorial, but the most widely suspected mechanism is the amyloid cascade hypothesis: Beta-amyloid proteins accumulate in the central nervous system, forming plaques that impair neuronal function. In recent years, advances have led to the development of targeted therapies with monoclonal antibodies. These drugs: Work by degrading amyloid plaques Slow the rate of cognitive decline and disease progression Have major side effects, most notably the development of amyloid-related imaging abnormalities (ARIA) ARIA may present as edema, effusion, or microhemorrhages, which are only detectable on MRI Symptoms can include headache, vertigo, or focal neurologic deficits that mimic stroke For patients presenting to the emergency department with stroke-like symptoms, it is important to consider whether they have a history of Alzheimer's disease and whether they are taking these medications. This guides decisions about imaging and treatment: The work-up may require MRI, which can delay thrombolytic or endovascular therapy in patients with true strokeConversely, treating a patient with ARIA using thrombolytics increases the risk of bleeding and other complications References Ebell MH, Barry HC, Baduni K, Grasso G. Clinically Important Benefits and Harms of Monoclonal Antibodies Targeting Amyloid for the Treatment of Alzheimer Disease: A Systematic Review and Meta-Analysis. Ann Fam Med. 2024 Jan-Feb;22(1):50-62. doi: 10.1370/afm.3050. PMID: 38253509; PMCID: PMC11233076. Ma C, Hong F, Yang S. Amyloidosis in Alzheimer's Disease: Pathogeny, Etiology, and Related Therapeutic Directions. Molecules. 2022 Feb 11;27(4):1210. doi: 10.3390/molecules27041210. PMID: 35209007; PMCID: PMC8876037. Perneczky R, Dom G, Chan A, Falkai P, Bassetti C. Anti-amyloid antibody treatments for Alzheimer's disease. Eur J Neurol. 2024 Feb;31(2):e16049. doi: 10.1111/ene.16049. Epub 2023 Sep 11. PMID: 37697714; PMCID: PMC11235913. Summarized by Ashley Lyons, OMS3 | Edited by Ashley Lyons and Jorge Chalit, OMS4 Donate: https://emergencymedicalminute.org/donate/

House Call Vet Café Podcast
Ep. 81: Quorum Sensing Molecules?!: Diagnosing UTIs, Ear Infections, & More On House Calls; Meet Scientist & QSM Dx Founder Ed Goluch

House Call Vet Café Podcast

Play Episode Listen Later Sep 30, 2025 57:53


Ed Goluch is the founder and CEO of QSM Diagnostics, makers of the Otter eQ laboratory instrument platform and FetchDx mail-in testing kits. Prior to QSM, Ed was a tenured professor in the Department of Chemical Engineering at Northeastern University. Ed earned his PhD in Bioengineering from the University of Illinois at Urbana-Champaign, and he has over 60 publications and several patents in the areas of sensors, microfluidics, and biophysics. He lives in Somerville, MA, with his wife, Liz, two Alaskan Klee Kai dogs, Odin and Gunnar, and two Balinese cats, Loki and Bandit. Topics covered in this episode:  Ed Goluch's journey into the veterinary space with QSM Diagnostics Understanding Quorum-Sensing Molecules The applications and benefits of QSM Technology for veterinarians Antibiotic stewardship Antibiogram and antibiotic resistance Streamlined mobile diagnostics FetchDx mail-in testing kits The House Call Vet Academy experience Links & Resources:  Visit the QSM Diagnostics website to learn more Find QSM Diagnostics on Instagram Find QSM Diagnostics on Facebook The House Call Vet Academy Resources:  Download Dr. Eve's FREE House Call & Mobile Vet Biz Plan Find out about the House Call Vet Academy online CE course Learn more about Dr. Eve Harrison Learn more about the Concierge Vet Mastermind Get your FREE Concierge Vet Starter Kit mini course Learn more about SoulShine Space For Vets. Use discount code SHINE15 for 15% OFF SoulShine Space For Vets! (Available for a limited time only! Rules and restrictions apply.) Learn more about 1-to-1 coaching for current & prospective house call & mobile vets Get House Call Vet swag Learn more about the House Call & Mobile Vet Virtual Conference Register TODAY for the House Call & Mobile Vet Virtual Conference, February 7th-8th, 2026!!!!!! Here's a special gift from me as a huge thank you for being a part of our wonderful House Call Vet Cafe podcast community! ☕️ GET 20% OFF your Four Sigmatic Mushroom Coffee when you order through this link! 4Sig truly is my favorite!!! Enjoy it in good health, my friends! Music:  In loving memory of Dr. Steve Weinberg.  Intro and outro guitar music was written, performed, and recorded by house call veterinarian Dr. Steve Weinberg.  Thank you to our sponsors!  Chronos  O3 Vets  This podcast is also available in video on our House Call Vet Cafe YouTube channel 

La Parfumerie Podcast - Avis Parfum
Avis Marque : Escentric Molecules

La Parfumerie Podcast - Avis Parfum

Play Episode Listen Later Sep 25, 2025 9:55


Dans le cadre de notre petit Top 20 des pires marques de Parfumerie de Niche... voici notre avis sur Escentric Molecules !Consulter le Top complet : ⁠⁠⁠plus mauvaises marques de Parfum de niche⁠⁠Retrouvez nous sur ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠notre canal ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Telegram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ou ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠notre chaîne Whatsapp⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, on y poste des inédits, des avis fumants, en toute indépendance. Le site est là pour vous servir, comme toujours : ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠LaParfumerie-Podcast.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠, ainsi que notre cher ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠groupe Discord⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ !

Harold's Old Time Radio
Columbia Workshop 36-08-22 The March of the Molecules - There Must Be Something Else

Harold's Old Time Radio

Play Episode Listen Later Sep 24, 2025 29:25 Transcription Available


Columbia Workshop 36-08-22 The March of the Molecules - There Must Be Something Else

Vital Signs
Ep 61: Co-Founder of Chai Discovery Joshua Meier on 99% Faster Drug Discovery, BioTech's AlphaGo Moment, Building Photoshop for Molecules

Vital Signs

Play Episode Listen Later Sep 22, 2025 56:45


In this episode, Jacob sits down with Joshua Meier, co-founder of Chai Discovery and former Chief AI Officer at Absci, to explore the breakthrough moment happening in AI drug discovery. They discuss how the field has evolved through three distinct waves, with the current generation of companies finally achieving success rates that seemed impossible just years ago.  The conversation covers everything from moving drug discovery out of the lab and into computers, to why AI models think differently than human chemists, to the strategic decisions around open sourcing foundational models while keeping design capabilities proprietary. It's an in-depth look at how AI is fundamentally changing pharmaceutical innovation and what it means for the future of medicine. Check out the full Chai-2 Zero-Shot Antibody report linked here: https://www.biorxiv.org/content/10.1101/2025.07.05.663018v1.full.pdf (0:00) Intro(1:25) The Evolution of AI in Drug Discovery(5:14) Current State and Future of AI in Biotech(10:08) Challenges and Modalities in Therapeutics(14:44) Data Generation and Model Training(22:52) Open Source and Model Development at Chai(29:52) Open Source Models and Their Impact(34:36) How Should Chai-2 Be Used?(38:53) The Future of AI in Pharma and Biotech(42:46) Key Milestones and Metrics in AI-Driven Drug Discovery(47:20) Critiques and Hesitation(54:01) Quickfire Out-Of-Pocket: https://www.outofpocket.health/

Homeopathy for Mommies
Introducing ASEA: How Redox Molecules Support the Body's Repair System

Homeopathy for Mommies

Play Episode Listen Later Sep 19, 2025


In this special panel discussion, host Sue Meyer is joined on this panel discussion with guests Buffy Donahoo, ND, BCCAHP, CDP, CNHP, Maureen Hansen CCH, and Amy Stacy, RN, BSN, CHPN to explore an exciting breakthrough in natural health: redox signaling technology. Sue shares her own recovery story following a serious accident, and the panel […] The post Introducing ASEA: How Redox Molecules Support the Body's Repair System appeared first on Ultimate Homeschool Podcast Network.

Grow Everything Biotech Podcast
147: "Shhh…They're Talking: Holoclara's Dr. Andrea Choe Tunes Into Worm Signals for Health”

Grow Everything Biotech Podcast

Play Episode Listen Later Sep 19, 2025 63:45


What if we could treat debilitating diseases by listening in on the "secret, invisible language" of worms? In this groundbreaking episode, we talk with Dr. Andrea Choe, Co-Founder and CEO of Holoclara, who uncovered a "universal worm language" used for hundreds of millions of years. Dr. Choe reveals how our modern "aggressive hygiene routine" removed the worms we co-evolved with, leading to a rise in allergic and autoimmune diseases. Discover how her team is pioneering a new class of safe, orally available therapies by synthesizing worm-derived molecules that "rebalance" our immune systems and have already blocked disease in animal models. This is a fascinating journey from a fundamental discovery in evolutionary biology to the cutting edge of biotech innovation.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at www.messaginglab.com/groweverythingChapters:(00:00:00) Welcome to Grow Everything Podcast(00:00:18) NYC Biotech and Climate Week Recap(00:08:43) Science News: Comets and Octopuses(00:15:17) Meet Dr. Andrea Choe(00:15:52) From Researcher to Founder: The Call to Action(00:17:25) Discovering the Universal "Worm Language"(00:25:11) Connecting Worm Secretions to Therapeutics(00:29:49) How Modern Hygiene Created an Immune Imbalance(00:34:35) Navigating the Hurdles of Natural Medicine(00:38:50) Holoclara's Mission to Treat Eosinophilic Esophagitis (EoE)(00:42:25) Holoclara's Phase 1 Safety and Trial Results(00:51:03) Moonshot Vision: A "Worm Atlas" of Molecules(00:52:28) The Strategy for Patenting Natural Molecules(00:54:33) Worm Superpowers & Immune Myths(00:58:25) Reflecting on Nature's Untapped Answers(01:02:41) Coming Up on Grow EverythingEpisode Links:HoloclaraHuman Genome project Diary of a worm - Doreen Cronin Wildlife of Our Bodies - Rob DunnSuzanne Lee  Ep Glennis Mehra EpEllen Jorgensen EpInnolabsNucleate Biolabs NYU LangoneGenspaceBiotech Without Borders Newlab Climate Week Event - sign up and get tickets now! Interstellar Comet Moving Through Our Solar SystemTopics Covered: immune system, biotherapeutics, worms, evolution, helminthic immunomodulation, medicine, pharmaceuticals  Have a question or comment? Message us here:Text or Call (804) 505-5553Instagram  / Twitter / LinkedIn / Youtube / Grow Everything

The Asia Climate Finance Podcast
Ep69 Beyond Hype: Making Green Molecules Commercially Viable, ft Alexander Tancock, InterContinental Energy

The Asia Climate Finance Podcast

Play Episode Listen Later Sep 17, 2025 40:10 Transcription Available


Comments, guest ideas: theasiaclimatecapitalpodcast@gmail.comHow do you scale green hydrogen from a laboratory curiosity to industrial reality? Alexander Tancock, CEO of Intercontinental Energy, reveals the breakthrough P2H2 Node system that's turning massive renewable projects into factory-produced “Lego blocks.”With numerous projects across three continents and backing from strong financial partners, Intercontinental Energy isn't just making green hydrogen—they're creating green iron to decarbonise steel production and building new trade corridors between Australia's vast renewable resources and Asia's industrial heartlands.Alex shares why the hydrogen hype faded, how government partnerships became crucial, and why 2028 could mark the tipping-point for commercially viable green molecules at oil- and gas-scale.REF: InterContinental EnergyABOUT ALEX: Alexander Tancock is the CEO and Chairman of the Board of InterContinental Energy, a global leader in large-scale green hydrogen development who has been at the forefront of the industry for more than 10 years. Under his leadership, the company has pioneered a portfolio of groundbreaking projects, with its three flagship projects attracting partnerships from some of the largest names in energy. With backing from major institutional investors like GIC and Hy24, InterContinental Energy has established itself at the forefront of the green molecule sector. The company's innovative team and approach extend beyond project development, and into giga scale enabling technology through its patented P2(H2)NodeTM architecture. Alex's expertise and strategic insights make him a significant voice in the energy sector.FEEDBACK: Email Host | HOST, PRODUCTION, ARTWORK: Joseph Jacobelli | MUSIC: Ep0-29 The Open Goldberg Variations, Kimiko Ishizaka Ep30-50 Orchestra Gli Armonici – Tomaso Albinoni, Op.07, Concerto 04 per archi in Sol - III. Allegro. | Ep51 – Brandenburg Concerto No. 4 in G, Movement I (Allegro), BWV 1049 Kevin MacLeod. Licensed under Creative Commons: By Attribution 4.0 License

Men in Charge
Men in Charge in Brief(s): New Spam Filter--Pain Molecules!

Men in Charge

Play Episode Listen Later Sep 15, 2025 5:00


In cleaning out the latest bit of cultural detritus from the show's spam filter, Tony and Kevin face an existential dilemma.

Cosmic Peach
Detoxifying The Blood With High Frequency Molecules (Feat. Kelly Fitshizzle)

Cosmic Peach

Play Episode Listen Later Sep 12, 2025 88:07 Transcription Available


Hello and welcome back to the show! Today we have an awesome returning guest and personal friend, Kelly Fitshizzle, to talk to us about how we can detoxify our blood with high frequency molecules, begin the anti-aging process and so much more! If you are interested in learning more about what we talked about today, please email Kelly directly at the email below!Email:Kellyfogelbach@gmail.comProduct info:https://www.reverseaging.infoKelly's Instagram:https://www.instagram.com/kellyfitzshizzle?igsh=ZTl3ajBrd2d0aGJz

The Other Side of Weight Loss
From Neck Skin to Miracle Molecules: The Anti-Aging Skin Care Secrets No One Talks About with Amitay Eschel

The Other Side of Weight Loss

Play Episode Listen Later Aug 30, 2025 97:21


Curious about the truths behind anti-aging skincare? What if you could unlock the secrets to timeless skin without falling for industry hype? Join us as Amitay Eschel, CEO of Young Goose, exposes the insincere promises of the skincare world and shares genuine insights into cellular rejuvenation. Are you wondering how societal pressures shape our pursuit of youth? What are the real roles of nutrition, peptides, and physical health in maintaining a youthful appearance? Discover the importance of informed skincare decisions, and explore the fine line between reversing the appearance of aging and reducing biological age. Could cutting-edge ingredients like NAD and spermidine be game-changers for your skin? How can ethical beauty practices triumph over industry giants? Listen in to learn how aligning company and consumer values can lead to groundbreaking skincare partnerships and foster a supportive community. In this episode, we uncover: How cellular rejuvenation trumps superficial fixes in the quest for youthful skin. Why informed decision making is crucial for popular treatments like Botox and microneedling. The role of nutrition, peptides, and physical health in achieving a youthful appearance. How pioneering skincare products mimic hyperbaric chamber effects for anti-aging benefits. Why collaboration and ethical practices are vital in the ever-evolving skincare industry. Check out this episode to unravel the mysteries of skincare innovation and ethical beauty practices. Tune in to transform your approach to timeless skin and empower your skincare journey!     Get 10% off your Young Goose order here.     Sponsors Maui Nui is offering a free 12-pack of snack sticks with your first order of $79 or more. Just go to mauinuivenison.com/hormone to grab yours. Get 15% off Masszymes By BiOptimzers products at bioptimizers.com/hormone with coupon code HORMONE. Get 20% off your KION Aminos at getkion.com/hormone.     Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada.   Visit karenmartel.com to explore our comprehensive programs: Bioidentical Hormone Replacement Therapy Individualized Weight Loss Programs  Peptide Therapy for weight loss    Interested in our NEW Peptide Weight Loss Program? Join today and get all the details here.   Join our Women's Peri and Post Menopause Group Coaching Program, OnTrack, TODAY!   To our nursing audience members, our podcasts qualify for nursing CE @ RNegade.pro. Provide # CEP17654.   Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert   Karen's Facebook Karen's Instagram

Boost Your Biology with Lucas Aoun
333. Natural MUSCLE BUILDING Supplements & Novel Ingredients With The Tourist of Molecules

Boost Your Biology with Lucas Aoun

Play Episode Listen Later Aug 29, 2025 63:57


In this episode of the Boost Your Biology podcast, Lucas Aoun welcomes Lloyd Siewert, a prominent figure in the supplement industry. They discuss Lloyd's journey into the world of supplements, the benefits of Shilajit, emerging trends in the supplement space, and the importance of nitric oxide boosters. The conversation is rich with insights on how various supplements can enhance performance and overall health, making it a must-listen for anyone interested in optimizing their wellness through supplementation.Relevant links:Lloyd's IG: https://www.instagram.com/tourist_of_molecules/ Lloyd's Supplement Store: https://newtownsupplementstore.com.au/Check Out My Website For Coaching, Recommended Products and Much More:https://www.boostyourbiology.com/ Disclaimer:The information provided in this podcast episode is for entertainment purposes and is NOT MEDICAL ADVICE. If you have any questions about your health, contact a medical professional. This content is strictly the opinions of Lucas Aoun and is for informational and entertainment purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult with their doctors or qualified health professionals regarding specific health questions. Neither Lucas Aoun nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this content. All consumers of this content especially taking prescription or over-the-counter medications should consult their physician before beginning any nutritional, supplement or lifestyle program.Chapters00:00 Introduction to the Supplement World02:01 Lloyd's Journey into Supplements16:02 The Power of Shilajit35:26 Emerging Trends in Supplements50:53 Nitric Oxide Boosters and Their Impact Hosted on Acast. See acast.com/privacy for more information.

Biologia em Meia Hora
Suco de clorofila

Biologia em Meia Hora

Play Episode Listen Later Aug 29, 2025 25:46


Será que o suco de clorofila faz bem para a saúde? Separe trinta minutinhos do seu dia e descubra, com a Mila Massuda, quanto dessa fama da água com clorofila tem fundamento científico e quanto é só marketing esperto, embalado em suco verde e garrafa bonita.Apresentação: Mila Massuda (@milamassuda)Roteiro: Mila Massuda (@milamassuda) e Emilio Garcia (@emilioblablalogia)Revisão de Roteiro: Vee AlmeidaTécnico de Gravação: Julianna Harsche (@juvisharsche)Editora: Angélica Peixoto (@angewlique)Mixagem e Masterização: Bruno Midões (@bruno_midoes) Produção: Prof. Vítor Soares (@profvitorsoares), Matheus Herédia (@Matheus_Heredia), BláBláLogia (@blablalogia), Caio de Santis (@caiodesantis) e Biologia em Meia Hora (@biologiaemmeiahora)Gravado e editado nos estúdios TocaCast, do grupo Tocalivros (@tocalivrosREFERÊNCIASHAYES, M.; FERRUZZI, M. G. Update on the Bioavailability and Chemopreventative Mechanisms of Dietary Chlorophyll Derivatives. Nutrition Research, jun. 2020.MARTINS, T. et al. Enhancing Health Benefits through Chlorophylls and Chlorophyll-Rich Agro-Food: A Comprehensive Review. Molecules, v. 28, n. 14, p. 5344, 11 jul. 2023.

Science Focus Podcast
The tiny molecules tackling the planet's biggest challenges

Science Focus Podcast

Play Episode Listen Later Aug 28, 2025 35:15


In this episode, we're joined by Professor Omar Yaghi – a pioneer of materials chemistry whose inventions are shaping the future of clean energy, clean air, and even clean water. He's best known for creating metal–organic frameworks, or MOFs, and covalent organic frameworks, COFs – ultra-porous materials that can capture carbon, store hydrogen, and even pull drinking water out of desert air. His work has opened up an entirely new field of chemistry, and his breakthroughs are now being developed into technologies that could help us tackle some of the biggest challenges of the 21st century. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Conversations With Pearl
From Surviving to Thriving: Shining Your Light with Dr. Ellen Mosti

Conversations With Pearl

Play Episode Listen Later Aug 27, 2025 56:35


Send us a textIn this inspiring episode of Soulful Self-Care Conversations, host Pearl Chiarenza sits down with Dr. Ellen Mosti—holistic health coach, transformational speaker, and founder of Lightness One All. With her unique blend of expertise in pharmacy, theology, energy healing, and coaching, Dr. Ellen guides women to heal from trauma, release limiting patterns, and rediscover their inner radiance.Together, Pearl and Dr. Ellen dive deep into the truths of self-care, boundaries, and the courage it takes to shine your light unapologetically in the world.What You'll Hear in This Episode:✨ Little Ellen's Dream – From aspiring nurse and hairdresser to pharmacist and healer, Dr. Ellen shares how her childhood passions shaped her purpose.✨ The Limits of Medication – Why Dr. Ellen left a 25-year career in pharmacy to explore what lies beneath symptoms and uncover root causes of illness.✨ Feel It to Heal It – The connection between suppressed emotions, trauma, and disease—and how creating safe spaces to feel allows true healing to begin.✨ Breaking People-Pleasing Patterns – How saying “yes” to everything depletes us, why boundaries matter, and how to recognize when people-pleasing is actually manipulation.✨ The Journey to Shine – Dr. Ellen opens up about divorce, fear, and rediscovering play, creativity, and joy later in life.✨ From Simply Surviving to Radically Thriving – A look into her empowering book and the five steps she created to help women unleash their unstoppable selves.Powerful Quotes from Dr. Ellen:“You've got to feel it to heal it.”“People pleasing is actually manipulation—we're trying to control how others respond to us.”“If you're at the bottom of your to-do list, you'll never get to you.”“The older I got, the more I let go of fear—and the freer and more joyful life became.”“We are all geniuses and miracles. Because we are here, we deserve to thrive.”Resources & Links Mentioned:

Chemistry Made Simple
How Quantum Mechanics makes the atom 3 dimensional, effects the shape of molecules, and dictates the periodic table's configuration

Chemistry Made Simple

Play Episode Listen Later Aug 25, 2025 7:58


The download mentioned: Chemistrymadesimple.net/2In this episode we consider how quantum mechanics effects the atomic model and more:There's more to electron shellsSubshells and orbitals3D shape of orbitalsOrbitals, bond angles and shape of moleculesThe reason the periodic table gets broader down the table Find out how I can help you throughout your chemistry A-Level here.--------------------------------------------------------------------------------------------Want to know more, or support the show? Become a Patreon supporter of the podcast and get more from each episode patreon.com/chemistrymadesimpleFind out more about the programme mentioned in the episode Chemistry Made Simple academyContact me:Instagram @chemistrymadesimpleEmail Matthew@ChemistryMadeSimple.netJoin the discussion at the Chemistry Made Simple podcast community.

The Science Show -  Separate stories podcast
The origin of complex molecules and how they made it to Earth

The Science Show - Separate stories podcast

Play Episode Listen Later Aug 23, 2025 7:08


Sara Russell explains the latest theory of how complex molecules were formed in the outer reaches of the Solar System and made their way to planets in the inner Solar System including Earth.

Many Minds
From the archive: Of molecules and memories

Many Minds

Play Episode Listen Later Aug 21, 2025 75:10


Hi friends! We're taking a much-needed August pause—we'll have new episodes for you in September. In the meanwhile, enjoy this pick from our archives! _____ [originally aired February 8, 2024] Where do memories live in the brain? If you've ever taken a neuroscience class, you probably learned that they're stored in our synapses, in the connections between our neurons. The basic idea is that, whenever we have an experience, the neurons involved fire together in time, and the synaptic connections between them get stronger. In this way, our memories for those experiences become minutely etched into our brains. This is what might be called the synaptic view of memory—it's the story you'll find in textbooks, and it's often treated as settled fact. But some reject this account entirely. The real storehouses of memory, they argue, lie elsewhere.  My guest today is Dr. Sam Gershman. Sam is Professor of Psychology at Harvard University, and the director of the Computational Cognitive Neuroscience Lab there. In a recent paper, he marshals a wide-ranging critique of the synaptic view. He makes a compelling case that synapses can't be the whole story—that we also have to look inside the neurons themselves.  Here, Sam and I first discuss the synaptic view and the evidence that seems to support it. We then talk about some of the problems with this classic picture. We consider, for example, cases where memories survive the radical destruction of synapses; and, more provocatively, cases where memories are formed in single-celled organisms that lack synapses altogether. We talk about the dissenting view, long lurking in the margins, that intracellular molecules like RNA could be the real storage sites of memory. Finally, we talk about Sam's new account—a synthesis that posits a role for both synapses and molecules. Along the way we touch on planaria and paramecia; spike-timing dependent plasticity; the patient H.M.; metamorphosis, hibernation, and memory transfer; the pioneering work of Beatrice Gelber; unfairly maligned ideas; and much, much more. Before we get to it, one important announcement: Applications are now open for the 2024 Diverse Intelligences Summer Institute (or DISI)! The event will be held in beautiful, seaside St Andrews, Scotland, from June 30 to July 20. If you like this show—if you like the conversations we have and the questions we ask—it's a safe bet that you'd like DISI. You can find more info at disi.org—that's disi.org. Review of applications will begin on Mar 1, so don't delay.  Alright friends, on to my conversation about the biological basis of memory with Dr. Sam Gershman. Enjoy!   Notes and links 4:00 - A general audience article on planarian memory transfer experiments and the scientist who conducted them, James V. McConnell.  8:00 - For more on Dr. Gershman's research and general approach, see his recent book and the publications on his lab website.  9:30 - A brief video explaining long-term potentiation. An overview of “Hebbian Learning.” The phrase “neurons that fire together wire together” was, contrary to widespread misattribution, coined by Dr. Carla Shatz here. 12:30 - The webpage of Dr. Jeremy Gunawardena, Associate Professor of Systems Biology at Harvard University. A recent paper from Dr. Gunawardena's lab on the avoidance behaviors exhibited by the single-celled organism Stentor (which vindicates some disputed, century-old findings).   14:00 - A recent paper by C. R. Gallistel describing some of his views on the biological basis of memory.   19:00 - The term “engram” refers to the physical trace of a memory. See recent reviews about the so-called search for the engram here, here, and here.   20:00 - An article on the importance of H.M. in neuroscience.  28:00 - A review about the phenomenon of spike-timing dependent plasticity. 33:00 - An article, co-authored by former guest Dr. Michael Levin, on the evidence for memory persistence despite radical remodeling of brain structures. See our episode with Dr. Levin here. 35:00 - A study reporting the persistence of memories in decapitated planarians. A popular article about these findings.  36:30 - An article reviewing one chapter in the memory transfer history. Another article reviewing evidence for “vertical” memory transfer (between generations). 39:00 - For more recent demonstrations of memory transfer, see here and here. 40:00 - A paper by Dr. Gershman, Dr. Gunawardena, and colleagues reconsidering the evidence for learning in single cells and describing the contributions of Dr. Beatrice Gelber. A general audience article about Gelber following the publication of the paper by Dr. Gershman and colleagues. 45:00 – A recent article arguing for the need to understand computation in single-celled organisms to understand how computation evolved more generally.  46:30 – Another study of classical conditioning in paramecia, led by Dr. Todd Hennessey. 49:00 – For more on plant signaling, see our recent episode with Dr. Paco Calvo and Dr. Natalie Lawrence.  56:00 – A recent article on “serial reversal learning” and its neuroscientific basis.  1:07:00 – A 2010 paper demonstrating a role for methylation in memory.   Recommendations The Behavior of the Lower Organisms, by Herbert Spencer Jennings Memory and the Computational Brain, by C. R. Gallistel and Adam Philip King Wetware, by Dennis Bray   Many Minds is a project of the Diverse Intelligences Summer Institute, which is made possible by a generous grant from the John Templeton Foundation to Indiana University. The show is hosted and produced by Kensy Cooperrider, with help from Assistant Producer Urte Laukaityte and with creative support from DISI Directors Erica Cartmill and Jacob Foster. Our artwork is by Ben Oldroyd. Our transcripts are created by Sarah Dopierala. Subscribe to Many Minds on Apple, Stitcher, Spotify, Pocket Casts, Google Play, or wherever you listen to podcasts. You can also now subscribe to the Many Minds newsletter here! We welcome your comments, questions, and suggestions. Feel free to email us at: manymindspodcast@gmail.com. For updates about the show, visit our website or follow us on Twitter (@ManyMindsPod) or Bluesky (@manymindspod.bsky.social).

Nutrients
The Case of the Missing Molecules

Nutrients

Play Episode Listen Later Aug 21, 2025 11:35 Transcription Available


Parkinson's disease has long been defined by the death of neurons in the brain. Yet, decades before tremors appear, the first signs emerge quietly in the gut. Recent evidence reveals a puzzling disappearance: microbial pathways that once produced two well-known compounds fall silent. Their absence strips away protective metabolites, erodes the intestinal barrier, and leaves neurons exposed to toxins that ignite α-synuclein fibrils. Could the vanishing of two simple vitamins be an overlooked trigger, and a potential target, in the unfolding mystery of Parkinson's disease?00:00 Introduction to Parkinson's Disease00:35 Early Signs and Gut Connection01:19 The Braak Hypothesis and Vagus Nerve02:08 Gut Microbiome and Vitamin Pathways03:10 Global Meta-Analysis and Key Findings04:37 Impact of Vitamin Deficiencies08:57 Potential for Vitamin Supplementation11:20 Conclusion and Future ImplicationsPMID: 37314861

Astronomy Daily - The Podcast
Cosmic Connections: Uranus's New Moon, Rogue Planets, and the Devil Comet's Water Mystery

Astronomy Daily - The Podcast

Play Episode Listen Later Aug 20, 2025 11:51 Transcription Available


New Moon Discovered Around Uranus: Astronomers have confirmed the discovery of a tiny new moon orbiting Uranus, measuring just five miles in diameter. This marks the first new addition to Uranus's moon family in over 20 years, highlighting the ongoing exploration of our solar system's outer planets. The moon, temporarily designated S 2023 U1, was spotted using the Magellan telescopes in Chile and is believed to be a captured object from the Kuiper Belt, shedding light on the dynamics of Uranus's moon system.- The Enigma of Richie Planets: Revolutionary findings from the James Webb Space Telescope suggest that rogue planets, previously thought to be solitary wanderers, may actually be forming their own moons. Observations in the Orion Nebula revealed discs of gas and dust surrounding these planets, indicating they could be creating mini solar systems. This challenges traditional models of planetary formation and opens up new avenues for understanding the nature of these elusive worlds.- Sibling Asteroids Richie and Bennu: Exciting new research confirms that the asteroids Richie and Bennu are siblings, fragments of a larger parent body that was shattered in a collision. Analysis of samples returned from both asteroids reveals a wealth of water-bearing clay minerals and organic molecules, supporting the theory that asteroids played a crucial role in delivering the ingredients for life to Earth.- The Devil Comet's Water Mystery: The Devil Comet, officially known as 12 P. Pons Brooks, has been found to possess water with an isotopic signature nearly identical to that of Earth's oceans. This discovery strengthens the theory that ancient comets contributed to the formation of Earth's water, suggesting a cosmic connection that links us to these icy wanderers.For more cosmic updates, visit our website at astronomydaily.io. Join our community on social media by searching for #AstroDailyPod on Facebook, X, YouTube Music, TikTok, and our new Instagram account! Don't forget to subscribe to the podcast on Apple Podcasts, Spotify, iHeartRadio, or wherever you get your podcasts.Thank you for tuning in. This is Anna and Avery signing off. Until next time, keep looking up and stay curious about the wonders of our universe.✍️ Episode ReferencesNew Moon Discovery[NASA](https://www.nasa.gov/)Richie Planets Research[James Webb Space Telescope](https://www.jwst.nasa.gov/)Richie and Bennu Analysis[JAXA](https://www.jaxa.jp/)Devil Comet Findings[ALMA](https://www.almaobservatory.org/)Astronomy Daily[Astronomy Daily](http://www.astronomydaily.io/)Become a supporter of this podcast: https://www.spreaker.com/podcast/astronomy-daily-space-news-updates--5648921/support.Sponsor Details:Ensure your online privacy by using NordVPN. To get our special listener deal and save a lot of money, visit www.bitesz.com/nordvpn. You'll be glad you did!Sponsor Details:Ensure your online privacy by using NordVPN. To get our special listener deal and save a lot of money, visit www.bitesz.com/nordvpn. You'll be glad you did!Become a supporter of Astronomy Daily by joining our Supporters Club. Commercial free episodes daily are only a click way... Click Here

People Behind the Science Podcast - Stories from Scientists about Science, Life, Research, and Science Careers
826: Visualizing Molecules to Understand Links Between Structure and Function - Dr. Beth Stroupe

People Behind the Science Podcast - Stories from Scientists about Science, Life, Research, and Science Careers

Play Episode Listen Later Aug 18, 2025 43:14


Dr. Beth Stroupe is a Professor in the Department of Biological Science and the Institute of Molecular Biophysics at Florida State University (FSU). She is also Director of the Molecular Biophysics Graduate Program there. Research in Beth's lab focuses on understanding what molecules and proteins look like. This is important for better understanding how these molecules work, both from a basic science perspective and with an eye towards controlling molecules for clinical applications. They use a variety of different techniques that allow them to visualize these very tiny molecules. When she's not working, Beth and her partner enjoy spending quality time with their two cats, as well as growing black-eyed peas and other vegetables in their garden, kayaking, hiking, and exploring the great outdoors. Beth completed her undergraduate training at Wake Forest University where she majored in chemistry and minored in music. She was awarded her PhD in biochemistry from the Scripps Research Institute. Afterwards, Beth conducted postdoctoral research at Brandeis University before joining the faculty at FSU where she is today. In our interview, Beth shares more about her life and science.

Kerusso Daily Devotional
On Miracles and Molecules

Kerusso Daily Devotional

Play Episode Listen Later Aug 14, 2025 3:04 Transcription Available


A political science major at a major university was having coffee with a campus pastor. The pastor knew that the student was wrestling with doubt about the existence of God and said to him, “John, you know all of us wonder at some point if it's all real or not. For example, there are quite a few stories in the Bible that are just hard to believe. Jonah and the whale and all that.” John smiled and said, “No, that's not my problem. What I wonder about is how God could care about me. I've done some really bad things and have had some really bad things done to me. I just can't understand the concept of forgiveness.”There you have it. Doubts about the faith come from all directions. While one person cannot bring herself to believe in miracles, another cannot forgive himself for the wrong things he's done, and can't fathom how God could. Thomas Jefferson actually cut out the miraculous sections of the Bible. He couldn't believe in what some would call the God of the Bible. Francis Crick, the co-discoverer of DNA, thought that Christianity was just a collection of mythical stories. And what about those who want to see the proof, they like evidence and feel a need to make an intellectual case for our faith. The New Testament writer Luke was like that. He wrote in Acts and the Gospel of Luke about the importance of eyewitness sightings of Jesus and His miracles. Lots of people debate whether evolution and religion are compatible or not. And this is a big stumbling block to believe for many. We all believe something, but our minds can struggle at times to grasp the big stuff, the infinite universe. While for others who doubt, the struggle is more internal. They're so grieved by their own sin, they can't accept that God could love them.Maybe the most famous verse in the Bible is John 3:16, which says, “For God so loved the world that he gave his one and only son, that whoever believes in him shall not perish, but have eternal life.” However, few quote the next verse which says, “For God did not send his son into the world to condemn the world, but to save the world through him.” It isn't God's wish to condemn you. Instead, He loves you and wants to give you assurance that life is more than struggle and molecules. Whether you're looking for evidence to believe the Bible or you just need to know that God loves you, try not to focus too much on your objections. Own them, but just tell God as a child would, that you're struggling to understand it all.Will you pray with me? Father, your grace saves us from a life of struggle with sin, and we are accepted by you. Thank you for putting up with our up-and-down faith. In Jesus' name, amen. Change your shirt, and you can change the world! Save 15% Off your entire purchase of faith-based apparel + gifts at Kerusso.com with code KDD15.

Unsupervised Learning
Ep 72: Co-Founder of Chai Discovery Joshua Meier on 99% Faster Drug Discovery, BioTech's AlphaGo Moment, Building Photoshop for Molecules

Unsupervised Learning

Play Episode Listen Later Aug 13, 2025 57:15


In this episode, Jacob sits down with Joshua Meier, co-founder of Chai Discovery and former Chief AI Officer at Absci, to explore the breakthrough moment happening in AI drug discovery. They discuss how the field has evolved through three distinct waves, with the current generation of companies finally achieving success rates that seemed impossible just years ago.  The conversation covers everything from moving drug discovery out of the lab and into computers, to why AI models think differently than human chemists, to the strategic decisions around open sourcing foundational models while keeping design capabilities proprietary. It's an in-depth look at how AI is fundamentally changing pharmaceutical innovation and what it means for the future of medicine. Check out the full Chai-2 Zero-Shot Antibody report linked here: https://www.biorxiv.org/content/10.1101/2025.07.05.663018v1.full.pdf [0:00] Intro[2:10] The Evolution of AI in Drug Discovery[6:09] Current State and Future of AI in Biotech[11:15] Challenges and Modalities in Therapeutics[15:19] Data Generation and Model Training[23:59] Open Source and Model Development at Chai[28:35] Protein Structure Prediction and Diffusion Models[30:57] Open Source Models and Their Impact[35:41] How Should Chai-2 Be Used?[39:34] The Future of AI in Pharma and Biotech[43:51] Key Milestones and Metrics in AI-Driven Drug Discovery[48:24] Critiques and Hesitation[55:06] Quickfire With your co-hosts: @jacobeffron - Partner at Redpoint, Former PM Flatiron Health @patrickachase - Partner at Redpoint, Former ML Engineer LinkedIn @ericabrescia - Former COO Github, Founder Bitnami (acq'd by VMWare) @jordan_segall - Partner at Redpoint

SpaceTime with Stuart Gary | Astronomy, Space & Science News
ERIS 1: Australia's Orbital Rocket Launch Attempt and the Cosmic Origins of Life

SpaceTime with Stuart Gary | Astronomy, Space & Science News

Play Episode Listen Later Aug 4, 2025 24:11


In this episode of SpaceTime, we delve into significant developments in space exploration, from Australia's latest rocket launch attempt to groundbreaking theories about the origins of life.Australia's ERIS 1 Rocket Launch: A Learning ExperienceIn a dramatic turn of events, Gilmour Space's ERIS 1 rocket experienced a failure just seconds after liftoff, marking Australia's first orbital rocket launch in years. Despite the setback, CEO Adam Gilmour emphasizes the lessons learned from the test flight, which will inform the design and operation of future launches. The rocket's ascent was initially promising, but engine failures led to a crash shortly after clearing the launch tower. Fortunately, no injuries or environmental damage occurred, and the mission provided valuable data that will enhance the next attempt.Life's Origins: A Cosmic PerspectiveA new study suggests that the building blocks of life may have originated in outer space rather than on Earth. Using the ALMA radio telescope, astronomers detected complex organic molecules in the protoplanetary disk of the protostar UH V883 Orionis. These findings indicate that essential compounds, such as ethylene glycol and glycolonitrile, are not only present in various cosmic environments but may also be the precursors to amino acids and other vital biological components. This research supports the notion that the seeds of life are widespread throughout the universe.Boeing's Starliner Delays ContinueBoeing's Starliner spacecraft faces further delays, now pushed back to at least 2026 before it can carry humans into space. Ongoing technical issues have plagued the project, including helium leaks and thruster control problems. NASA is working closely with Boeing to address these challenges, but the timeline for crewed missions remains uncertain as SpaceX continues to lead in transporting astronauts to the International Space Station.www.spacetimewithstuartgary.com✍️ Episode ReferencesAstrophysical Journal Lettershttps://iopscience.iop.org/journal/1538-4357NASA's Commercial Crew Programhttps://www.nasa.gov/exploration/commercial/crew/index.htmlGilmour Spacehttps://gilmourspace.com/Become a supporter of this podcast: https://www.spreaker.com/podcast/spacetime-space-astronomy--2458531/support.00:00 A new study says the evolution of life may well have origins in outer space00:47 Gilmour Space's Ares 1 orbital rocket crashed two seconds after launch10:37 A new study says the evolution of life may have origins in outer space11:28 Astronomers find 17 complex organic molecules in distant planet forming disk19:35 New study finds images can shape public opinion regardless of true facts22:06 World Meteorological Organization says megaflash stretched 829km in 2017

Pharma Intelligence Podcasts
Poolbeg CEO On The Biotech's Big Bet On Small Molecules

Pharma Intelligence Podcasts

Play Episode Listen Later Aug 4, 2025 35:40


In the latest episode of the In Vivo Podcast, Jeremy Skillington, CEO of Poolbeg Pharma, discussed the company's ambitious pipeline and strategic direction.

Biohacking with Brittany
Want to Age Slower? The 3 Longevity Molecules Every Woman Should Know

Biohacking with Brittany

Play Episode Listen Later Jul 11, 2025 29:15


In this Q&A episode, we strip the science-speak out of longevity and hand you the practical takeaways.  I unpack spermidine, NRF2, sirtuins and NAD—three buzzwords that can actually become game-changing tools when you understand how they work inside a woman's body. I share the vetted products in my personal stack, free lifestyle hacks, and a quick framework to choose what suits your goals and genetics—so biohacking stays simple, empowering, and tailored to your life. WE TALK ABOUT:  01:20 – Today's hot-seat Q&A: Spermidine, NRF2, NAD, sirtuins, and stacking strategy  07:25 – What spermidine actually does: Autophagy without the fast (SpermidineLIFE code: BIOHACKINGBRITTANY) 09:30 – NRF2 pathway 101: Flipping your antioxidant “master switch”  13:10 – Natural NRF2 activators 18:20 – NAD decoded: Why your mitochondria runs on this co-enzyme  20:45 – Best—and worst—ways to raise NAD: NOVOS (code: BIOHACKINGBRITTANY) 23:30 – Sirtuins unlocked: Longevity genes that need NAD to work  25:00 – The synergy play: When stacking three pathways makes sense  27:10 – My personal protocol & dosing tips SPONSORS: Swap restless nights for real recovery with Magnesium Breakthrough by BiOptimizers (code: BIOHACKINGBRITTANY) — the full-spectrum formula I trust for calmer nerves, balanced hormones, and deep, restorative sleep. RESOURCES: Trying to conceive? Join my Baby Steps Course to optimize your fertility with biohacking. Free gift: Download my hormone-balancing, fertility-boosting chocolate recipe. Explore my luxury retreats and wellness events for women. Shop my faves: Check out my Amazon storefront for wellness essentials. The DNA Blueprint episode with Kashif Khan Kid Gut Resilience: Birth, Stress & Health with Ara Katz of Seed LET'S CONNECT: Instagram, TikTok, Facebook Shop my favorite health products Listen on Spotify, Apple Podcasts, YouTube Music

Translating Aging
Molecules to medicine: The translational landscape of aging interventions (Panel discussion at BAAM 2025)

Translating Aging

Play Episode Listen Later Jul 9, 2025 47:59


In this special episode, host Chris Patil (VP-Media, BioAge) moderates a live panel discussion at the 25th Bay Area Aging Meeting at UCSF, bringing together six leading voices across the aging research ecosystem to tackle one of the field's most critical challenges: how to move promising discoveries from the laboratory to therapies that can benefit patients.The distinguished panel spans academia, industry, and scientific publishing, featuring Janine Sengstack (CEO, Junevity), Saul Villeda (Professor, UCSF), Jodi Nunnari (Director, Bay Area Institute of Science, Altos Labs), Sebastien Thuault (Chief Editor, Nature Aging), Anne Brunet (Professor, Stanford), and Nir Barzilai (Professor, Albert Einstein College of Medicine). Together, they explore the most promising research directions for clinical impact, the revolutionary tools enabling modern aging research, and the structural challenges that must be overcome to bring longevity therapies to market.Listeners will gain insights into the emerging science of cellular rejuvenation, the importance of systemic factors in aging, how to balance high-risk discovery with practical drug development, and the cultural shifts needed to better prepare the next generation of scientists for translational work. The panel also addresses the regulatory challenges of targeting aging itself as an indication and offers candid advice for young researchers navigating this rapidly evolving field.The Finer Details:Emerging research directions with the greatest clinical potential: cellular senescence, rejuvenation and repair, DNA methylation clocks, and understanding what makes aging biomarkers tickThe revolution in cellular and spatial resolution tools and how single-cell technologies are revealing cell-type-specific aging responsesSystemic factors and the remarkable plasticity remaining in aging organisms that can be unlocked through interventionsThe critical importance of starting with human data and working backward to validate targets and approachesChallenges unique to aging biotech: the need for aging-specific cellular assays, testing in older animal models, and genetic validationCultural and structural barriers between academia and industry, including the shift from mechanism-focused to mission-driven researchBalancing high-risk fundamental discovery with the practical needs of drug development and clinical translationThe regulatory landscape for aging interventions and potential pathways to FDA approval beyond traditional disease indicationsAdvice for young scientists: embracing rejection as part of the process, finding passion, working as teams, and considering diverse career paths in the growing longevity ecosystemQuotes:"Our goal as a company is to increase human health span, and the way I like to frame that more colloquially is we want to increase the number of happy, healthy years each person gets to spend on Earth." - Janine Sengstack"There is an exquisite amount of plasticity left in an aging organism, both within the tissues, within the cells. There is plasticity that we can actually tap into." - Saul Villeda"Burn bright, but don't burn out." - Jodi Nunnari"The challenge that we run into is that there are so many combinations that very quickly it would become intractable to line up enough test tubes to test them all." - Sebastien Thuault, on the complexity of aging interventions"We love our job. If not, we would not be doing it. I would do it again in a heartbeat... you get paid to play, to ask the questions that interest you, the approaches that interest you to play with who you want to—it is a fantastic job." - Saul Villeda"Our life is a life of rejection...and still, we're having fun and making an advance. So don't give up." - Nir Barzilai

The Synthesis of Wellness
186. The Gut-Immune Axis, Intestinal Barrier Function, & Vitamin D₃ | Activated 1,25-dihydroxyvitamin D₃ and Immune Function, Vitamin D Testing, & More

The Synthesis of Wellness

Play Episode Listen Later Jul 4, 2025 14:28


In this encore episode, we highlight vitamin D₃ in gastrointestinal health, with a focus on intestinal barrier function and the gut-immune axis. We discuss how vitamin D is metabolized into its active form, 1,25-dihydroxyvitamin D, and how 1,25-dihydroxyvitamin D can support the intestinal mucosa, while highlighting the intestinal epithelium and immune cells in the lamina propria. Through this, we further detail the role of regulatory T cells in supporting immune balance and modulating immune function.Topics:1. Introduction - Highlighting intestinal barrier function and the gut-immune axis with a focus on vitamin D₃ 2. Vitamin D Synthesis and Metabolism - Skin and 7-dehydrocholesterol; dietary intake.- Transported through the bloodstream bound to vitamin D binding protein.- First hydroxylation in the liver to form 25-hydroxyvitamin D₃ (25(OH)D₃).- Testing.- Second hydroxylation in the kidney to form the active 1,25 dihydroxyvitamin D₃ (1,25(OH)₂D₃).- Local activation also occurs. 3. Intestinal Barrier Anatomy - The intestinal epithelium forms a selectively permeable monolayer that interfaces with the gut lumen.- Covered by a mucus layer: mucins, antimicrobial peptides, secretory IgA.- Mucus layer provides physical and biochemical protection.- Tight junction proteins and paracellular permeability.- Molecules crossing the epithelium. - Disruption of tight junctions, immune cell exposure to luminal contents.- The lamina propria and Gut-Associated Lymphoid Tissue (GALT). - Maintaining tolerance while defending against pathogens.  4. Vitamin D's Role in Barrier Support and Immune Modulation - 1,25-dihydroxyvitamin D₃, tight junction integrity, immune regulation, and more.- Regulatory T Cells (Tregs) and immune balance.   5. Vitamin D₂ and D₃- D₃ (cholecalciferol) is more biologically effective and binds DBP more strongly.  6. Vitamin D Levels - Levels observed in autoimmune conditions, IBS, and more.- Symptoms.- Insufficient and excessive levels of vitamin D can be detrimental.- Multi-system.  7. Conclusion - Multifactorial: Numerous factors regulate vitamin D levels.- Gastrointestinal health root cause approach.Thanks for tuning in!Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow Chloe on TikTok @chloe_c_porterVisit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more!

The MindBodyBrain Project
Wisdom Wednesdays: Should the 'longevity molecules' NMN and NR be on your supplement list?

The MindBodyBrain Project

Play Episode Listen Later Jun 24, 2025 11:04 Transcription Available


Longevity Supplements: Do NMN and NR Actually Work? Read on to find out what the research says. Overview:In this week's episode, we dive into the popular supplements NMN and NR that are touted to increase longevity and healthspan. We break down what these supplements actually are, what the research says about their effects on muscle and physical function, and whether you should spend your money on them. Key Takeaways: 0:45 - What are NMN and NR? Precursors to NAD+, which declines with age 2:30 - Animal studies show benefits, but what about humans?3:45 - Results of a systematic review of RCTs in older adults on muscle strength and physical function 5:00 - Studies sponsored by industry show benefits, but lower quality evidence6:30 - Are they worth spending your money on? CTA: Dive into the research and decide for yourself - listen to the full episode now!See omnystudio.com/listener for privacy information.

The Red Light Report
C60 vs. ESS60: The MUST KNOW Difference Between These Two Molecules w/ Chris Burres

The Red Light Report

Play Episode Listen Later Jun 19, 2025 83:17


In this in-depth conversation, Dr. Mike Belkowski reunites with Chris Burres, co-founder of SES Research and the original supplier of the carbon 60 (C60) used in the historic 2012 French longevity study where Wistar rats lived 90% longer than the control group. This episode centers around the rebranding of BioLight's C60 product to BioESS60, with an emphasis on scientific rigor, quality assurance, and consumer safety.   Chris and Dr. Mike unpack why the C60 supplement market has become compromised, how the name ESS60 (Elemental Safe Spheres) was created to separate quality-controlled, biologically safe carbon 60 from industrial or fraudulent versions, and what the latest science suggests about its mechanism of action inside the mitochondria.   Chris introduces the BOSS Theory — Buffering Oxidative Stress System — explaining how ESS60 functions as a selective antioxidant that targets negatively charged ROS without interfering with redox signaling. This distinguishes it from traditional antioxidants like vitamin C or E, which are non-selective and degrade after use. Chris compares ESS60 to a “molecular sponge” that protects the cell's internal “prairie” from the torrential stress “storms” of modern life.   Alongside that, the two discuss how ESS60 and methylene blue may have synergistic roles in mitochondrial optimization — MB enhances ATP production efficiency, while ESS60 buffers the resulting oxidative stress. The conversation also touches on the evolving understanding of nitric oxide (NO) signaling and how not all NO inhibition is necessarily harmful — especially when considering MB's selective inhibition of inducible NO synthase (iNOS). If you found the information in today's episode with Chris Burres particularly interesting and/or compelling, please share it with a family member, friend, colleague and/or anyone that you think could benefit and be illuminated by this knowledge. Sharing is caring :)As always, light up your health! - Key Quotes: “ESS60 is a selective antioxidant — it buffers only the negatively charged reactive oxygen species that cause damage, while preserving the signaling functions of the others.” – Chris Burres   “Taking something in the morning and positively impacting sleep at night — that's not normal. But that's what people consistently report with ESS60.” – Chris Burres “The supplement industry is the Wild West. That's why we're creating separation between industrial-grade C60 and ultra-clean, biologically safe S60.” – Dr. Mike Belkowski - Key Points: 00:00 – Introduction: C60 vs. ESS60 and Mitochondrial Health Focus 01:17 – Guest Intro: Chris Burres and the 2012 Longevity Study 03:05 – Biohacking Conferences: Networking and New Tech Insights 05:36 – Nano Oxygen Bubbles: A Hyperbaric Alternative 17:35 – ESS60 Explained: Benefits and Mechanisms 30:06 – Buffering Oxidative Stress: The Boss Theory 44:41 – C60 vs. ESS60: Navigating the Supplement Market 48:43 – Exposing Fraud in the C60 Space: Safety Concerns 52:29 – The Switch to ESS60: Ensuring Consumer Safety 56:27 – Purity and Processing: Why ESS60 is Different 1:00:11 – Dosage and Long-Term Use of ESS60 1:06:19 – Cycling ESS60: Is It Necessary? 1:10:55 – ESS60 and Cancer: Preventative Potential 1:15:27 – Current Research: CRP Study and Future Directions 1:21:49 – Closing Thoughts: Integrity in Health and Wellness - Where to learn more from and about Chris Burres: Instagram LinkedInBook by Chris Burres:Living Longer and Better - Upcoming BioLight Events:   Returning to Nature (Quantum Health Retreat), June 26 - 27 (Franklin, TN) - Officially introducing...... BioESS60!!   It is the exact same high-quality unparalleled carbon 60 supplement, but with an updated, upgraded product name to emphasize and underline that BioLight utilizes the only "pharmaceutical grade" carbon 60 in the world: ESS60.For the next week, get 20% off all BioESS60 purchases!*Code: ESS60podcastDiscount is valid through 6/26, midnight, PST*must use "single" option and then you can increase to your desired quantity   Shop BioESS60 by clicking here! - Dr. Mike's #1 recommendations: Water products: Water & Wellness Grounding products: Earthing.com EMF-mitigating products: Somavedic Blue light-blocking glasses: Ra Optics - Stay up-to-date on social media: Dr. Mike Belkowski: Instagram LinkedIn   BioLight: Website Instagram Facebook

Vibration 歪波音室
L'été Français 法兰西之夏:一个炽热悠闲的世界

Vibration 歪波音室

Play Episode Listen Later Jun 19, 2025 43:15


夏日的模样,在每个人的心中都会有不同的画面,但当温度升高、热浪袭来,我相信所有人心底那份对悠长假期、充满活力与闲适自由的向往,肯定都是一样的。现在已然是盛夏时分啦,我想邀请你一起浸入一场特别的夏日体验~这期节目,将以法国音乐独特的魅力来作为媒介——它拥有一种浑然天成的松弛律动,萦绕着一种恰到好处的微醺氛围,借助法国的音乐,我们一起创造一个炽热、悠闲、充满活泼生命力的夏日世界。并且我希望借此契机,也能打破一些固有的印象标签,让你能听到法国音乐极具张力的另一面:它不仅仅是浪漫的香颂或精致的小调, 更拥有着反叛、时尚和先锋的棱角,希望能带给你意料之外的惊喜与触动。

ghosts quand molecules ys lize breezin shanghai restoration project
The Guest House
Narrated Essay: In the Realm of the River

The Guest House

Play Episode Listen Later Jun 18, 2025 9:49


You're invited next September 20-26, 2026, to The Tender Harvest, a week-long retreat amidst the golden hues and organic bounty of the world-class Ballymaloe House in County Cork, Ireland. Each day will feature yoga, meditation, farm-to-table meals, and curated excursions—plus ample time for rest, self-nurturance, and imagination.The sound of flowing water soothes most nervous systems, but particularly those acclimatized to the desert, and particularly upon waking. I have struggled with sleep disturbances for most of my adult life, so it's rare for me to experience the weight and metabolic satisfaction of a good night's rest. But twice last month, I found myself receiving what we can call river medicine: first while visiting friends at their cabin in the Pecos Wilderness, and again east of Aspen, Colorado, while teaching at Beyul Retreat, a guest ranch along the Frying Pan River, a tributary of the Roaring Fork River.River medicine is like this: surrounded by tall, sappy pines, I found myself one early morning in the atmospheric valley between sleeping and waking, an integrative field of frequencies and forms. You know the place. Even now, I do not know for certain: did the river, by some charm of consciousness, stream into my dreamscape and stir me awake? Or was it the dream that pulsated forward into the matrix of a new day? What I can say is that I felt a bright, hydrous intelligence moving in ripples and waves through my body—clarifying and tonifying, calming neurons and glial cells in their watery beds, clearing layers of baked-in tension like grit loosened from a soaking pan. And for a time, I floated above the push of the day, appearing and disappearing and reappearing to myself.In the wake of hours that followed, to my delight, I noticed a quiet reverberation—an elemental answer quelling a wordless, needful thirst.Science offers a partial explanation for this. Water has a high dielectric constant, meaning it reduces the electrostatic attraction between charged particles, which helps substances like salt crystals separate and dissolve more easily. I would also propose that water's properties of solubility, absorption, and transmission apply to its natural ability to clean and balance the bioenergetic forces of being human.When a river twists and turns, it releases negative ions into the air. Microscopically, this process is dynamic—even violent. Molecules spill over rocks and tumble forward, rushing and colliding, breaking apart, and thereby transferring electrons and charging the surrounding air. But I find comfort in this science of fluid revitalization. New, more supportive structures can form when old ones give way, pointing to how, beyond turmoil and devastation, we too can hope for vital transformation.Years ago, I read a New York Times article called “Where Heaven and Earth Come Closer,” in which journalist Eric Weiner wrote about “thin places,” locations where the gap between the ordinary and extraordinary—or, better yet, transordinary—thins out.“Thin” seemed to me a strange choice to describe where the air thickens with meaning. But Celts and early Christians held that a small but distinct distance, like three feet, separates heaven and earth—and that distance dissolves in “places that beguile and inspire, sedate and stir, places where, for a few blissful moments [we] loosen [our] death grip on life, and can breathe again.”Many a thin place has been built by human hands. Early in my career, I worked for the United Nations Foundation in collaboration with UNESCO's World Heritage Centre, and developed the sensible habit of visiting the most treasured cathedrals, temples, and sanctuary sites wherever I found myself in the world. Jama Masjid in Delhi, Sacré-Cœur in Paris, Tirta Empul in Bali, Newgrange in Ireland, and the Church of the Holy Sepulchre in Jerusalem: each has a distinct energetic signature that lives in my memory, a resonance born of its purpose and the accumulation of countless prayers that infuse the surrounding air.But thin places are more often found than made. Mountains, canyons, coral palaces—they are organic monuments to mysticism and ready reminders of our humble size before nature. As Weiner writes, “Thin places relax us, yes, but they also transform us—or, more accurately, unmask us. In thin places, we become our more essential selves.”In this sense, thin places evoke qualities of alchemy and revelation. In traveling to Beyul Retreat, I recalled how the Vajrayana Buddhist term “beyul” refers to hidden valleys believed to be sanctuaries blessed by enlightened teachers, places where the land itself is animate. A beyul holds the wisdom that rivers, trees, and even rocks are not objects but mandalas — living altars, ineffable and intricate in their aliveness.Aptly named, Beyul Retreat is a place where the boundary between perception and imagination feels more permeable. The land electrifies with new growth as summer approaches: dandelion confetti bursts open in the meadows, aspen trees shimmy, and fresh sage scents the air. Each morning, as the river's murmur moves through the valley, calypso orchids bloom in the shade while the pointed ears of silver fox pups perk up from behind cool, wet stones.In the imaginal realm of childhood, there are many such beyuls, many thin places. There are fern groves and swallow lairs, stars nestled in apple cores and galaxies in lightning bugs, and lobe-handed sycamore leaves at the wild end of the yard.We tend to think of nature as speaking in symbols, but its directness transmits rather than approximates. “The world is not made of objects; it is a communion of subjects,” writes Stephen Harrod Buhner, author of Plant Intelligence and the Imaginal Realm. “To enter the imaginal realm is to give permission to the ineffable within us, to allow the world to speak through our senses, our dreams, our longings.”To commune is to listen with our whole body, to notice the most basic and vital exchange of breath and circumstance that underpins our existence. To allow for a metamorphosis of our attention. And when we realize the subjectivity of the world, we can discover strange and wonderful ways of joining the conversation. Like us, the aspens drink water and eat light. They have instincts and work to protect their lives. And did you know that the dark spots resembling eyes on the smooth, pale bark are scars left behind when the tree sheds lower branches that receive less sunlight? Look how this porous watchfulness is directed in our direction, how the forest offers us its attention.Together, we are making sense of being human in an era of radical change. Your presence here matters. Thank you for reading, sharing, ‘heart'ing, commenting, and subscribing to The Guest House. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit shawnparell.substack.com/subscribe

Dr. GPCR Podcast
Baking Molecules, Building Probes: When Chemists Think Like Biologists with Dr. Maria Majellaro / Dr. GPCR Podcast 168

Dr. GPCR Podcast

Play Episode Listen Later Jun 10, 2025 65:41


Watch the video version of this podcast episode:https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-168-with-dr.-maria-majellaro-from-celtarysVisit Celtarys' website in the Ecosystem: https://www.ecosystem.drgpcr.com/celtarys-research-dr-gpcr-ecosystemRead the DrGPCR x Celtarys Partnership Press Release: https://www.ecosystem.drgpcr.com/post/dr-gpcr-and-celtarys-research-join-forces-to-expand-access-to-innovative-gpcr-toolsLearn more about Celtarys Research: https://www.celtarys.com/---------------------------------Become a #DrGPCR Ecosystem Member---------------------------------Imagine a world in which the vast majority of us are healthy.The #DrGPCR Ecosystem is all about dynamic interactions between us working towards exploiting the druggability of #GPCRs. We aspire to provide opportunities to connect, share, form trusting partnerships, grow, and thrive together.---------------------------------To build our #GPCR Ecosystem, we created various enabling outlets.Premium YearlyPremium Yearly for TeamsDeveloping CountriesAre you a #GPCR professional?Subscribe to the Classified GPCR Weekly NewsListen and subscribe to #DrGPCRPodcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Hypnosis and relaxation |Sound therapy
Relax and decompress with the sound of the bowl, deeply resonate with the molecules in the human body, stimulate and adjust the energy flow of the body and mind

Hypnosis and relaxation |Sound therapy

Play Episode Listen Later Jun 9, 2025 16:47


Support this podcast at — https://redcircle.com/hypnosis-and-relaxation-sound-therapy9715/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

SpaceTime with Stuart Gary | Astronomy, Space & Science News
MOND vs. Dark Matter: A New Perspective on Cosmic Mysteries

SpaceTime with Stuart Gary | Astronomy, Space & Science News

Play Episode Listen Later Jun 6, 2025 23:58


Sponsor Details:This episode is brought to you with the support of Insta360 - the leaders in 360-degree video technology. To explore their innovative range and claim your special SpaceTime bonus, visit store.insta360.com and use the coupon code SpaceTime at checkout.In this episode of SpaceTime, we uncover exciting new research challenging our understanding of dark matter, reveal hidden treasures beneath the Earth's surface, and explore the potential for life on Titan, Saturn's enigmatic moon.Modified Newtonian Dynamics: A Dark Matter AlternativeRecent studies suggest that modified Newtonian dynamics (MOND) may serve as a viable alternative to the elusive dark matter hypothesis. This theory, proposed by physicist Mordecai Milgrom, modifies Newton's laws to explain the gravitational behavior observed in galaxies without relying on dark matter. We delve into the latest findings that support MOND, including a novel method for measuring gravity in wide binary star systems, which indicates that gravity may actually be stronger than Newton's predictions under certain conditions.Earth's Hidden Gold ReservesA groundbreaking study reveals that Earth's core may contain vast reserves of gold and other precious metals, far beyond what is accessible on the surface. Researchers discovered traces of ruthenium in volcanic rocks from Hawaii, suggesting that these metals originated from the core and are leaking into the mantle. This research opens new avenues for understanding Earth's internal dynamics and the movement of materials from the core to the surface.Searching for Life's Chemistry on TitanNASA's upcoming Dragonfly mission aims to investigate the intriguing chemistry of life on Titan, Saturn's largest moon. With its organic-rich environment and unique geological features, Titan presents an opportunity to study prebiotic chemistry in a way that Earth cannot. We explore how Dragonfly will analyze the moon's surface and atmosphere to uncover clues about the processes that may have led to the emergence of life, potentially reshaping our understanding of habitability in the universe.www.spacetimewithstuartgary.com✍️ Episode ReferencesAstrophysical Journalhttps://iopscience.iop.org/journal/0004-637XNaturehttps://www.nature.com/nature/Become a supporter of this podcast: https://www.spreaker.com/podcast/spacetime-space-astronomy--2458531/support.00:00 This is Space Time Series 28, Episode 68 for broadcast on 6 June 202501:00 Modified Newtonian dynamics as an alternative to dark matter12:15 Earth's hidden gold reserves22:30 Searching for life's chemistry on Titan30:00 Science report: Ancient tool-making from whale bones and quantum computing breakthroughs

Taiwanology
【Taiwanology Ep.48】Molecules of Resilience: Can Taiwan Power a Hydrogen Economy?

Taiwanology

Play Episode Listen Later May 27, 2025 28:34


As global powers pour billions into the hydrogen economy, Taiwan is just getting started. In this episode, we ask: Is Taiwan ready for the hydrogen economy? Could hydrogen be Taiwan's next move for energy security and net-zero goals? We explore what it will take for Taiwan to catch up, from industrial policy to infrastructure. - 03:30 From flour to fuel: How Linde LienHwa evolved into a hydrogen leader - 07:40 Why hydrogen? What makes it a game-changer in energy - 10:02 Hydrogen on the move: Its role in decarbonizing transportation - 16:00 Taiwan's challenge: Building up hydrogen infrastructure - 22:00 Rethinking energy: What must change in Taiwan's infrastructure to go net-zero Host: Kwangyin Liu, Senior Managing Editor of CommonWealth Magazine Guests: Christine Miao, Vice President of Corp. Communications & Head of Hydrogen Mobility, Linde LienHwa & Toby Collins, Managing Director of Lien Hwa New Energy Producers: Yayuan Chang, Weiru Wang *Learn what's holding back Taiwan's renewable energy ambitions — and what it will take to overcome. https://english.cw.com.tw/article/article.action?id=3689 *Share your thoughts: bill@cw.com.tw Powered by Firstory Hosting

Talk Nerdy with Cara Santa Maria
Proteins & SciComm w/ Maggie Fink

Talk Nerdy with Cara Santa Maria

Play Episode Listen Later May 26, 2025 56:30


In this episode of Talk Nerdy, Cara is joined by microbiologist, science communicator, Adjunct Professor at Indiana University South Bend and postdoctoral researcher at the University of Notre Dame, Dr. Maggie M. Fink. They discuss her newest co-authored book, “The Color of North: The Molecular Language of Proteins and the Future of Life.” Follow Maggie: @MaggieMFink

The Beautifully Broken Podcast
Peptides 101: Boost Sleep, Immunity & Energy with Precision Molecules | Dr. Adam Boender

The Beautifully Broken Podcast

Play Episode Listen Later May 19, 2025 76:53


In this episode, I sit down with Dr. Adam Boender—entrepreneur, peptide expert, and co-founder of Legacy BioScience—for a powerful exploration of what peptides really are, how they function in the body, and why they're a game-changing tool in the world of regenerative health. We unpack how peptides act as biological communicators to restore cellular function, improve efficiency, and accelerate healing. We also discuss the difference between deficiency and dysfunction, the pitfalls of cheap peptides, and how to approach peptide therapy with purpose and personalization. From BPC-157 and thymosin alpha-1 to epitalon and VIP, we explore therapeutic peptides that support gut health, immune resilience, longevity, and even deep REM sleep. Whether you're facing chronic illness or simply want to upgrade your biology, this episode will leave you empowered and informed.HIGHLIGHTS[1:58] - Peptides 101: What they are and how they work inside your body[5:45] - Is it really a deficiency or just inefficiency? Understanding cellular exhaustion[9:49] - Peptides vs. "moonshot medicine"—do they work without the lifestyle blueprint?[14:05] - From skeptic to believer: why peptides didn't work—until they did[15:47] - How to start: sourcing, safety, and what to look for in your first peptide[20:36] - BPC-157, SLU-PP-332, and other "Wolverine-like" peptides explained[25:35] - The impact of GLP-1s: beyond weight loss to metabolic and cognitive health[36:28] - The VIP + Epithalon duo that reset sleep and immune systems[48:20] - Thymosin Alpha-1 and immune modulation for Lyme, mold, and SIRS[51:56] - Don't go it alone: how to find trusted peptide consulting and support[55:31] - Frugal wellness: why a guided peptide protocol can save you money[1:02:59] - What labs are most helpful (and what peptides don't show up on)[1:05:05] - The most common health complaints Dr. Boender sees—and the peptide response[1:12:38] - What it means to be beautifully broken: Dr. Boender's heartfelt closing reflectionLINKS & RESOURCESLegacy BioScience: https://legacybioscience.com/#a_aid=BeautifullyBrokenUse code BEAUTIFULLYBROKEN for an exclusive discount on your orderResearch Articles & Guides: peptideresearcher.com::UPGRADE YOUR WELLNESS::Silver Biotics Wound Healing Gel: https://bit.ly/3JnxyDD (30% off)(Use Code: BEAUTIFULLYBROKEN for Discount)BEAM Minerals: http://beamminerals.com/beautifullybrokenUse code beautifullybroken for 20% offStemRegen: https://www.stemregen.co/products/stemregen?_ef_transaction_id=&oid=1&affid=52Code: beautifullybrokenLightPathLED: https://lightpathled.pxf.io/c/3438432/2059835/25794Code: beautifullybrokenCONNECT WITH FREDDIE CONNECT WITH FREDDIE Check out my website and store: (http://www.beautifullybroken.world) Instagram: (https://www.instagram.com/beautifullybroken.world/) YouTube: (https://www.youtube.com/@BeautifullyBrokenWorld)

The Synthesis of Wellness
177. The Gut-Immune Axis, Intestinal Barrier Function, & Vitamin D₃ | Activated 1,25-dihydroxyvitamin D₃ and Immune Function, Vitamin D Testing, & More

The Synthesis of Wellness

Play Episode Listen Later May 2, 2025 14:28


In this episode, we highlight vitamin D₃ in gastrointestinal health, with a focus on intestinal barrier function and the gut-immune axis. We discuss how vitamin D is metabolized into its active form, 1,25-dihydroxyvitamin D, and how 1,25-dihydroxyvitamin D can support the intestinal mucosa, while highlighting the intestinal epithelium and immune cells in the lamina propria. Through this, we further detail the role of regulatory T cells in supporting immune balance and modulating immune function.Topics:1. Introduction - Highlighting intestinal barrier function and the gut-immune axis with a focus on vitamin D₃ 2. Vitamin D Synthesis and Metabolism - Skin and 7-dehydrocholesterol; dietary intake.- Transported through the bloodstream bound to vitamin D binding protein.- First hydroxylation in the liver to form 25-hydroxyvitamin D₃ (25(OH)D₃).- Testing.- Second hydroxylation in the kidney to form the active 1,25 dihydroxyvitamin D₃ (1,25(OH)₂D₃).- Local activation also occurs. 3. Intestinal Barrier Anatomy - The intestinal epithelium forms a selectively permeable monolayer that interfaces with the gut lumen.- Covered by a mucus layer: mucins, antimicrobial peptides, secretory IgA.- Mucus layer provides physical and biochemical protection.- Tight junction proteins and paracellular permeability.- Molecules crossing the epithelium. - Disruption of tight junctions, immune cell exposure to luminal contents.- The lamina propria and Gut-Associated Lymphoid Tissue (GALT). - Maintaining tolerance while defending against pathogens.  4. Vitamin D's Role in Barrier Support and Immune Modulation - 1,25-dihydroxyvitamin D₃, tight junction integrity, immune regulation, and more.- Regulatory T Cells (Tregs) and immune balance.   5. Vitamin D₂ and D₃- D₃ (cholecalciferol) is more biologically effective and binds DBP more strongly.  6. Vitamin D Levels - Levels observed in autoimmune conditions, IBS, and more.- Symptoms.- Insufficient and excessive levels of vitamin D can be detrimental.- Multi-system.  7. Conclusion - Multifactorial: Numerous factors regulate vitamin D levels.- Gastrointestinal health root cause approach.Thanks for tuning in!Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow Chloe on TikTok @chloe_c_porterVisit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more!

The Health Ranger Report
Brighteon Broadcast News, Apr 28, 2025 – HIDDEN HEALTH SECRETS: Neuroprotective molecules in green tea, suppressed cancer cures and more

The Health Ranger Report

Play Episode Listen Later Apr 28, 2025 109:43


- Green Tea and Cognitive Benefits (0:10) - Critique of Pharmaceuticals and Big Pharma (2:39) - Green Tea and Brain Health (4:31) - Speed Cubing and Cognitive Training (10:47) - Green Tea and Cancer Prevention (15:59) - Green Tea and Heavy Metal Detoxification (24:45) - L-Theanine and Anxiety Relief (30:04) - Catechins and Polyphenols in Green Tea (36:21) - Green Tea Extracts and Supplements (39:14) - Green Tea and Cancer Therapy (50:57) - Colloidal Silver and Its Benefits (1:11:38) - Silver Nanoparticles and Cancer Research (1:23:02) - Historical and Metaphysical Significance of Metals (1:26:08) - Economic and Political Implications of Metals (1:27:53) - Challenges and Opportunities in Health and Science (1:30:08) - Personal Reflections and Future Plans (1:37:17) - Final Thoughts and Gratitude (1:41:15) For more updates, visit: http://www.brighteon.com/channel/hrreport NaturalNews videos would not be possible without you, as always we remain passionately dedicated to our mission of educating people all over the world on the subject of natural healing remedies and personal liberty (food freedom, medical freedom, the freedom of speech, etc.). Together, we're helping create a better world, with more honest food labeling, reduced chemical contamination, the avoidance of toxic heavy metals and vastly increased scientific transparency. ▶️ Every dollar you spend at the Health Ranger Store goes toward helping us achieve important science and content goals for humanity: https://www.healthrangerstore.com/ ▶️ Sign Up For Our Newsletter: https://www.naturalnews.com/Readerregistration.html ▶️ Brighteon: https://www.brighteon.com/channels/hrreport ▶️ Join Our Social Network: https://brighteon.social/@HealthRanger ▶️ Check In Stock Products at: https://PrepWithMike.com

Wisdom's Echo
Molecules by Dr. Cindy johnson

Wisdom's Echo

Play Episode Listen Later Apr 14, 2025 14:42


Molecules by Dr. Cindy johnson

Fated Mates
07.27: What I Did for a Duke: This Gentleman is Completely Composed of Revenge Molecules

Fated Mates

Play Episode Listen Later Mar 19, 2025 86:56


It's deep dive day here at Fated Mates and we're reading an absolute banger of a historical -- Julie Anne Long's fifth Pennyroyal Green book, What I Did for a Duke. We talk about great romance kisses, about age gaps and how they operate in books, about house parties and art and sacrifice and how sexy it is when someone actually sees you for who you are. If you haven't read this one yet, do yourself a favor and do it right now. It's so great.If you want more Fated Mates in your life, please join our Patreon, which comes with an extremely busy and fun Discord community! Join other magnificent firebirds to hang out, talk romance, and be cool together in a private group full of excellent people. Learn more at patreon.com.The BooksWhat I Did for a Duke by Julie Anne Long The Pennyroyal Green SeriesShow NotesThe main building you think of when you think of the New York Public Library with the lions is officially called the Stephen A. Schwarzman Building. From what I can tell, it didn't actually have anything to do with Andrew Carnegie, but he did donate $5 million to ensure that the New York Public Library had branch libraries in communities around the city. He also donated a lot of money to other things, that's a fun thing billionaires used to do. Read more about doing the forbidden kind of “romance stuff” in the library. Jen talked to the New York Public Library's Best New Romance List Committee Co-Chairs Kate Fais and Grace Loiacon back in February.In 2022, we recorded our “Break in case of emergency” episode, and it was in fact two sisters, Cait and Kara who requested the episode. PS: We are in emergency. Feel free to break those out now.Julie Anne Long's The Beast Takes a Bride was on our Best of 2024 episode. What I Did for a Duke is the 5th book in her Pennyroyal Green series. “It must have been a lie,” is what Jen's grandma Betty used to say if you lost your train of thought and couldn't remember what you were saying. This is a good speech from Crash Davis, the pitcher played by Kevin Costner in the 1988 movie Bull Durham (also, Nuke says “what's all that molecule stuff?” which is pretty funny considering the title of this episode).The Isabella Stewart Gardner Museum in Boston had a Titian exhibition back in 2022 called Women, Myth and Power, and it seems like a thing Genevive would have liked it a lot.

Ben Greenfield Life
EXOSOMES: Everything You Need To Know About the Darling Molecules of the Anti-Aging Industry, With JuveXO's Brian Pla.

Ben Greenfield Life

Play Episode Listen Later Mar 15, 2025 58:44


My guest Brian Pla’s journey from the finance sector to the forefront of regenerative medicine and biocosmetics illustrates his adept transition and entrepreneurial spirit. Initially making his mark in finance and co-founding a foreign currency trading firm, Pla’s subsequent venture into the medical field was sparked by his personal experience with cell-based therapies. This shift led him to introduce new approaches in precision medicine and cell-based treatments, contributing to advancements in non-invasive and minimally invasive procedures. In 2017, he founded Gentera Centers for Precision Medicine and Plastic Surgery, focusing on personalized care and precision medicine, guiding Gentera to become a recognized name in regenerative medicine. The company's innovative approach sets a new standard for rejuvenation by utilizing exosomes—tiny, naturally occurring messengers in the body that promote your appearance at the cellular level. This advanced science is redefining what’s possible in non-invasive treatments, offering solutions that improve skin elasticity, reduce fine lines, enhance radiance, and revitalize thinning hair. Full show notes: https://bengreenfieldlife.com/exosomepodcast Episode Sponsors: Ketone-IQ: Ketones are a uniquely powerful macronutrient that can cross the blood-brain barrier and increase brain energy and efficiency. With a daily dose of Ketone-IQ, you'll notice a radical boost in focus, endurance, and performance. Save 30% off your first subscription order of Ketone-IQ at Ketone.com/BENG. LeelaQ: Not only do LeelaQ’s products neutralize EMFs, increase ATP production, optimize HRV, and improve blood flow, but they've been third-party proven to do so in placebo-controlled double-blind studies. Visit leelaq.com/ben and use code BEN10 for 10% off. Jaspr: Breathe air so clean you can smell the difference with the Jaspr commercial-grade air purifier. Visit Jaspr.co/ben and use code BEN for 10% off. RoXiva: Try out this world-class multisensory RX1 lamp, featuring meticulously crafted light and sound journeys that guide you effortlessly and reliably into new and expanded states of awareness. Get yours now by going to roXiva.com/ben! Our Place: Upgrade to Our Place today and say goodbye to forever chemicals in your kitchen. Go to fromourplace.com and enter my code BEN at checkout to receive 10% off sitewide.See omnystudio.com/listener for privacy information.

The John Batchelor Show
Preview: Colleague Bob Zimmerman reports on the ISRO lunar lander Vikram that detects abundant water molecules on the moon. More later

The John Batchelor Show

Play Episode Listen Later Mar 12, 2025 1:31


Preview: Colleague Bob Zimmerman reports on the ISRO lunar lander Vikram that detects abundant water molecules on the moon. More later 1961

The Peter Attia Drive
#333 ‒ Longevity roundtable — the science of aging, geroprotective molecules, lifestyle interventions, challenges in research, and more | Steven Austad, Matt Kaeberlein, Richard Miller

The Peter Attia Drive

Play Episode Listen Later Jan 27, 2025 161:39


View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this special episode of The Drive, Peter introduces a brand-new roundtable format. Joined by three renowned experts in longevity science—Steven Austad, Richard Miller, and Matt Kaeberlein—the group explores the rapidly evolving field of geroscience. Together, they dive deep into topics like the relationship between healthspan and lifespan, evaluating interventions like rapamycin and senolytics, the role of epigenetic changes in aging, and whether GLP-1 receptor agonists hold geroprotective potential. They also tackle major challenges in funding and public acceptance of longevity research including how geroprotective interventions might be tested in humans. Packed with nuanced debate, humor, and groundbreaking insights, this episode is a must-listen for anyone fascinated by the science of aging. We discuss: The recent rise in public interest in longevity, misconceptions, and the link between healthspan and lifespan [3:45]; Redefining healthspan, the US healthcare paradox, and separating longevity science from commercial hype [12:30]; The need to redirect medical research from disease-specific models to aging-focused approaches [21:30]; Proactive healthcare: rethinking health, disease, and the role of aging [30:00]; Biologic age versus chronologic age, and the limitations and potential of epigenetic clocks [35:00]; The utility and drawbacks of the “hallmarks of aging” as a framework for research and funding [49:30]; The role of epigenetic changes in aging and the challenges of proving causality [56:45]; The translational challenges of moving aging research from preclinical studies to human applications [1:03:45]; Distinguishing between a biomarker of aging and aging rate indicators [1:17:15]; The difficulties of translating longevity research in mice to humans, and the difficulties of testing interventions in humans [1:21:15]; Exercise, aging, and healthspan: does exercise slow aging? [1:35:45]; Are GLP-1 receptor agonists geroprotective beyond caloric restriction effects? [1:41:00]; The role of senescent cells in aging, challenges with reproducibility in studies, and differing views on the value of current research approaches [1:46:15]; How funding challenges and leadership in NIH and other institutes impact the advancement of aging-related research [2:00:15]; Metformin: geroprotective potential, mechanisms, and unanswered questions [2:02:30]; Canagliflozin and rapamycin as geroprotective molecules: mechanisms, dosing strategies, and longevity potential [2:10:45]; Resveratrol and NAD precursors—a lack of evidence for anti-aging effects [2:22:45]; The potential of parabiosis and plasmapheresis to slow aging, the challenges in translating mouse studies to humans, and possible design for human studies [2:29:45]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

Science Friday
AI Is Coming Up With Brand New Molecules, Fueling Drug Discovery

Science Friday

Play Episode Listen Later Jan 27, 2025 19:00


A recent study in the journal Nature unveiled new proteins that can neutralize the deadliest of snake venoms. They're “new” in that they aren't found in nature—they were created in a lab, dreamed up by AI.Using AI to discover, or design, the building blocks of drugs is a fast-growing area of research. Another team of scientists out of Philadelphia is using AI to discover new antibiotics by resurrecting long-lost molecules from extinct species like neanderthals and woolly mammoths.We know what you're thinking: It sounds too sci-fi to be true.Flora Lichtman talks with two pioneers in the field about how AI is supercharging drug discovery: Dr. César de la Fuente, bioengineer and presidential associate professor at the University of Pennsylvania in Philadelphia, and Nobel laureate Dr. David Baker, director of the Institute for Protein Design and professor at the University of Washington in Seattle.Transcripts for each segment will be available after the show airs on sciencefriday.com.For our Los Angeles listeners: We're working on a story about the toxins left behind by the fires and we want to hear from you. How is this affecting you? Are you worried about the air and water and soil? How are you approaching clean-up? And what questions do you have?Leave us a voicemail at 1-646-767-6532 or send us an email at scifri@sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.