Podcast appearances and mentions of Bradley J Monk

Featuring perspectives from Dr Bradley J Monk and Dr David M O'Malley, including the following topics. Introduction (0:00) Ovarian Cancer; Role of HER2-Directed Therapy in Gynecologic Cancers — Dr O'Malley (4:36) Endometrial Cancer and Cervical Cancer — Dr Monk (27:59) CME information and select publications

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/VRN865. CME/MOC/NCPD/AAPA/IPCE credit will be available until April 16, 2025.Advancing ADCs in Gynecologic Cancers: Expert Insights on Recent Evidence, Implementation Strategies, and Patient Care In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, Foundation for Women's Cancer, and National Ovarian Cancer Coalition. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Daiichi Sankyo, Inc., ImmunoGen, Inc., and Seagen and Genmab.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/VRN865. CME/MOC/NCPD/AAPA/IPCE credit will be available until April 16, 2025.Advancing ADCs in Gynecologic Cancers: Expert Insights on Recent Evidence, Implementation Strategies, and Patient Care In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, Foundation for Women's Cancer, and National Ovarian Cancer Coalition. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Daiichi Sankyo, Inc., ImmunoGen, Inc., and Seagen and Genmab.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/VRN865. CME/MOC/NCPD/AAPA/IPCE credit will be available until April 16, 2025.Advancing ADCs in Gynecologic Cancers: Expert Insights on Recent Evidence, Implementation Strategies, and Patient Care In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, Foundation for Women's Cancer, and National Ovarian Cancer Coalition. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Daiichi Sankyo, Inc., ImmunoGen, Inc., and Seagen and Genmab.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/VRN865. CME/MOC/NCPD/AAPA/IPCE credit will be available until April 16, 2025.Advancing ADCs in Gynecologic Cancers: Expert Insights on Recent Evidence, Implementation Strategies, and Patient Care In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, Foundation for Women's Cancer, and National Ovarian Cancer Coalition. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Daiichi Sankyo, Inc., ImmunoGen, Inc., and Seagen and Genmab.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/VRN865. CME/MOC/NCPD/AAPA/IPCE credit will be available until April 16, 2025.Advancing ADCs in Gynecologic Cancers: Expert Insights on Recent Evidence, Implementation Strategies, and Patient Care In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, Foundation for Women's Cancer, and National Ovarian Cancer Coalition. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Daiichi Sankyo, Inc., ImmunoGen, Inc., and Seagen and Genmab.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/VRN865. CME/MOC/NCPD/AAPA/IPCE credit will be available until April 16, 2025.Advancing ADCs in Gynecologic Cancers: Expert Insights on Recent Evidence, Implementation Strategies, and Patient Care In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, Foundation for Women's Cancer, and National Ovarian Cancer Coalition. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Daiichi Sankyo, Inc., ImmunoGen, Inc., and Seagen and Genmab.Disclosure information is available at the beginning of the video presentation.

Featuring perspectives from Dr Bradley J Monk, including the following topics: Introduction (0:00) Case: A woman (gBRCA1) in her late 40s, 5 months after surgery and adjuvant paclitaxel/carboplatin for Stage II ovarian cancer, now with a single umbilical metastasis — Kellie E Schneider, MD (9:47) Case: A woman (gBRCA2) in her late 60s with Stage IIIC ovarian cancer after surgery and chemotherapy who has received primary olaparib maintenance for 3 years develops acute myeloid leukemia — Swati Vishwanathan, MD (17:21) Case: A woman in her early 60s presents with Stage IV ovarian cancer (BRCA wild-type, homologous recombination deficiency-positive) — Neil Morganstein, MD (22:53) Case: A woman (gBRCA2) in her late 40s with Stage IIIC primary peritoneal cancer receives carboplatin/paclitaxel after R0 debulking surgery; genetic testing results pending — Karim ElSahwi, MD (27:30) Case: A woman in her early 60s with PMH of breast cancer and with limited recurrence of ovarian cancer (BRCA wild-type, homologous recombination deficiency-positive) after chemotherapy and maintenance niraparib refuses to receive chemotherapy — Gigi Chen, MD (33:06) Case: A woman (gBRCA2) in her mid 60s with high-grade serous carcinoma of the fallopian tube undergoes surgery and chemotherapy/bevacizumab but cannot tolerate a PARP inhibitor and refuses to take another agent — Thomas P Morrissey, MD (40:51) Case: A woman (homologous repair deficiency-positive) in her mid 70s with ovarian cancer and disease progression on EPIK-O trial of alpelisib with olaparib tests positive for folate receptor alpha and receives mirvetuximab soravtansine — Lyndsay J Willmott, MD (45:46) Journal Club with Dr Monk (54:13) CME information and select publications

Dr Bradley J Monk from the Florida Cancer Specialists & Research Institute in West Palm Beach, Florida, discusses real-world patient cases and treatment strategies for ovarian cancer. CME information and select publications here (https://www.researchtopractice.com/MTPOvarian23/Part4).

Dr Bradley J Monk from the Florida Cancer Specialists & Research Institute in West Palm Beach, Florida, discusses real-world patient cases and treatment strategies for ovarian cancer.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/BVX865. CME/MOC/AAPA/IPCE credit will be available until December 10, 2024.The ABCs of ADCs for Gynecologic Cancer: Expert Insights on Effective Implementation and Practical Tips for Use in Patients With Cervical, Ovarian, or Endometrial Cancer In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Daiichi Sankyo, Inc., Eisai Inc., and Seagen and Genmab.Disclosure PolicyAll relevant conflicts of interest have been mitigated prior to the commencement of the activity.Faculty/Planner DisclosuresChair/PlannerBradley J. Monk, MD, FACS, FACOG, has a financial interest/relationship or affiliation in the form of:Consultant and/or Advisor for Acrivon Therapeutics; Adaptimmune Therapeutics plc.; Agenus Inc.; Akeso Biopharma Co., Ltd.; Amgen Inc.; Aravive; AstraZeneca; Bayer Corporation; Clovis Oncology; Eisai Inc.; Elevar, LLC; EMD Serono, Inc.; F. Hoffmann-La Roche Ltd./Genentech, Inc.; Genmab A/S/Seagen Inc.; The GOG Foundation Inc; Gradalis, Inc.; ImmunoGen, Inc.; Iovance Biotherapeutics, Inc.; Jiangsu Hengrui Pharmaceuticals Co., Ltd.; Karyopharm; Laekna Therapeutics; Merck & Co., Inc.; Mersana Therapeutics; Myriad Genetics, Inc.; Novartis Pharmaceuticals Corporation; Novocure GmbH; OncoC4, Inc.; Panavance Therapeutics Inc.; Pfizer; Pieris Pharmaceuticals, Inc.; Puma Biotechnology, Inc.; Regeneron Pharmaceuticals Inc.; Sorrento Therapeutics, Inc.; TESARO, Inc./GlaxoSmithKline; US Oncology Research, LLC; VBL Therapeutics; Verastem, Inc.; and Zentalis Pharmaceuticals.Grant/Research Support from US Oncology Research, LLC.Speaker for AstraZeneca; Clovis Oncology; Eisai Inc.; F. Hoffmann-La Roche Ltd./Genentech, Inc.; Merck & Co., Inc.; and TESARO, Inc./GlaxoSmithKline.Faculty/PlannerAna Oaknin, MD, PhD, has a financial interest/relationship or affiliation in the form of:Consultant and/or Advisor for Agenus Inc.; AstraZeneca; Clovis Oncology; Corcept Therapeutics; Deciphera Pharmaceuticals; Eisai Co., Ltd.; EMD Serono; Exelisis, Inc.; F. Hoffmann-La Roche; Genmab A/S; GlaxoSmithKline; ImmunoGen, Inc.; iTeos Therapeutics; Merck Sharp & Dohme de Espana SA; Mersana Therapeutics; Novocure GmbH; OncXerna Therapeutics, Inc.; Pharma Mar SA; Regeneron Pharmaceuticals Inc.; Seagen, Inc.; Shattuck Labs, Inc.; and Sutro Biopharma, Inc.Grant/Research Support from AbbVie Deutschland; Advaxis Inc.; Aeterna Zentaris; Amgen Inc.; Aprea Therapeutics AB; Bristol Myers Squibb; Clovis Oncology; Eisai Co., Ltd.; F. Hoffmann-La Roche; ImmunoGen, Inc.; Merck Sharp & Dohme de Espana SA; Millennium Pharmaceuticals Inc.; Pharma Mar SA; Regeneron Pharmaceuticals Inc; and Tesaro.Planning Committee and Reviewer DisclosuresPlanners, independent reviewers, and staff of PVI, PeerView Institute for Medical Education, do not have any relevant financial relationships related to this CE activity unless listed below.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/BVX865. CME/MOC/AAPA/IPCE credit will be available until December 10, 2024.The ABCs of ADCs for Gynecologic Cancer: Expert Insights on Effective Implementation and Practical Tips for Use in Patients With Cervical, Ovarian, or Endometrial Cancer In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Daiichi Sankyo, Inc., Eisai Inc., and Seagen and Genmab.Disclosure PolicyAll relevant conflicts of interest have been mitigated prior to the commencement of the activity.Faculty/Planner DisclosuresChair/PlannerBradley J. Monk, MD, FACS, FACOG, has a financial interest/relationship or affiliation in the form of:Consultant and/or Advisor for Acrivon Therapeutics; Adaptimmune Therapeutics plc.; Agenus Inc.; Akeso Biopharma Co., Ltd.; Amgen Inc.; Aravive; AstraZeneca; Bayer Corporation; Clovis Oncology; Eisai Inc.; Elevar, LLC; EMD Serono, Inc.; F. Hoffmann-La Roche Ltd./Genentech, Inc.; Genmab A/S/Seagen Inc.; The GOG Foundation Inc; Gradalis, Inc.; ImmunoGen, Inc.; Iovance Biotherapeutics, Inc.; Jiangsu Hengrui Pharmaceuticals Co., Ltd.; Karyopharm; Laekna Therapeutics; Merck & Co., Inc.; Mersana Therapeutics; Myriad Genetics, Inc.; Novartis Pharmaceuticals Corporation; Novocure GmbH; OncoC4, Inc.; Panavance Therapeutics Inc.; Pfizer; Pieris Pharmaceuticals, Inc.; Puma Biotechnology, Inc.; Regeneron Pharmaceuticals Inc.; Sorrento Therapeutics, Inc.; TESARO, Inc./GlaxoSmithKline; US Oncology Research, LLC; VBL Therapeutics; Verastem, Inc.; and Zentalis Pharmaceuticals.Grant/Research Support from US Oncology Research, LLC.Speaker for AstraZeneca; Clovis Oncology; Eisai Inc.; F. Hoffmann-La Roche Ltd./Genentech, Inc.; Merck & Co., Inc.; and TESARO, Inc./GlaxoSmithKline.Faculty/PlannerAna Oaknin, MD, PhD, has a financial interest/relationship or affiliation in the form of:Consultant and/or Advisor for Agenus Inc.; AstraZeneca; Clovis Oncology; Corcept Therapeutics; Deciphera Pharmaceuticals; Eisai Co., Ltd.; EMD Serono; Exelisis, Inc.; F. Hoffmann-La Roche; Genmab A/S; GlaxoSmithKline; ImmunoGen, Inc.; iTeos Therapeutics; Merck Sharp & Dohme de Espana SA; Mersana Therapeutics; Novocure GmbH; OncXerna Therapeutics, Inc.; Pharma Mar SA; Regeneron Pharmaceuticals Inc.; Seagen, Inc.; Shattuck Labs, Inc.; and Sutro Biopharma, Inc.Grant/Research Support from AbbVie Deutschland; Advaxis Inc.; Aeterna Zentaris; Amgen Inc.; Aprea Therapeutics AB; Bristol Myers Squibb; Clovis Oncology; Eisai Co., Ltd.; F. Hoffmann-La Roche; ImmunoGen, Inc.; Merck Sharp & Dohme de Espana SA; Millennium Pharmaceuticals Inc.; Pharma Mar SA; Regeneron Pharmaceuticals Inc; and Tesaro.Planning Committee and Reviewer DisclosuresPlanners, independent reviewers, and staff of PVI, PeerView Institute for Medical Education, do not have any relevant financial relationships related to this CE activity unless listed below.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/BVX865. CME/MOC/AAPA/IPCE credit will be available until December 10, 2024.The ABCs of ADCs for Gynecologic Cancer: Expert Insights on Effective Implementation and Practical Tips for Use in Patients With Cervical, Ovarian, or Endometrial Cancer In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Daiichi Sankyo, Inc., Eisai Inc., and Seagen and Genmab.Disclosure PolicyAll relevant conflicts of interest have been mitigated prior to the commencement of the activity.Faculty/Planner DisclosuresChair/PlannerBradley J. Monk, MD, FACS, FACOG, has a financial interest/relationship or affiliation in the form of:Consultant and/or Advisor for Acrivon Therapeutics; Adaptimmune Therapeutics plc.; Agenus Inc.; Akeso Biopharma Co., Ltd.; Amgen Inc.; Aravive; AstraZeneca; Bayer Corporation; Clovis Oncology; Eisai Inc.; Elevar, LLC; EMD Serono, Inc.; F. Hoffmann-La Roche Ltd./Genentech, Inc.; Genmab A/S/Seagen Inc.; The GOG Foundation Inc; Gradalis, Inc.; ImmunoGen, Inc.; Iovance Biotherapeutics, Inc.; Jiangsu Hengrui Pharmaceuticals Co., Ltd.; Karyopharm; Laekna Therapeutics; Merck & Co., Inc.; Mersana Therapeutics; Myriad Genetics, Inc.; Novartis Pharmaceuticals Corporation; Novocure GmbH; OncoC4, Inc.; Panavance Therapeutics Inc.; Pfizer; Pieris Pharmaceuticals, Inc.; Puma Biotechnology, Inc.; Regeneron Pharmaceuticals Inc.; Sorrento Therapeutics, Inc.; TESARO, Inc./GlaxoSmithKline; US Oncology Research, LLC; VBL Therapeutics; Verastem, Inc.; and Zentalis Pharmaceuticals.Grant/Research Support from US Oncology Research, LLC.Speaker for AstraZeneca; Clovis Oncology; Eisai Inc.; F. Hoffmann-La Roche Ltd./Genentech, Inc.; Merck & Co., Inc.; and TESARO, Inc./GlaxoSmithKline.Faculty/PlannerAna Oaknin, MD, PhD, has a financial interest/relationship or affiliation in the form of:Consultant and/or Advisor for Agenus Inc.; AstraZeneca; Clovis Oncology; Corcept Therapeutics; Deciphera Pharmaceuticals; Eisai Co., Ltd.; EMD Serono; Exelisis, Inc.; F. Hoffmann-La Roche; Genmab A/S; GlaxoSmithKline; ImmunoGen, Inc.; iTeos Therapeutics; Merck Sharp & Dohme de Espana SA; Mersana Therapeutics; Novocure GmbH; OncXerna Therapeutics, Inc.; Pharma Mar SA; Regeneron Pharmaceuticals Inc.; Seagen, Inc.; Shattuck Labs, Inc.; and Sutro Biopharma, Inc.Grant/Research Support from AbbVie Deutschland; Advaxis Inc.; Aeterna Zentaris; Amgen Inc.; Aprea Therapeutics AB; Bristol Myers Squibb; Clovis Oncology; Eisai Co., Ltd.; F. Hoffmann-La Roche; ImmunoGen, Inc.; Merck Sharp & Dohme de Espana SA; Millennium Pharmaceuticals Inc.; Pharma Mar SA; Regeneron Pharmaceuticals Inc; and Tesaro.Planning Committee and Reviewer DisclosuresPlanners, independent reviewers, and staff of PVI, PeerView Institute for Medical Education, do not have any relevant financial relationships related to this CE activity unless listed below.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/BVX865. CME/MOC/AAPA/IPCE credit will be available until December 10, 2024.The ABCs of ADCs for Gynecologic Cancer: Expert Insights on Effective Implementation and Practical Tips for Use in Patients With Cervical, Ovarian, or Endometrial Cancer In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Daiichi Sankyo, Inc., Eisai Inc., and Seagen and Genmab.Disclosure PolicyAll relevant conflicts of interest have been mitigated prior to the commencement of the activity.Faculty/Planner DisclosuresChair/PlannerBradley J. Monk, MD, FACS, FACOG, has a financial interest/relationship or affiliation in the form of:Consultant and/or Advisor for Acrivon Therapeutics; Adaptimmune Therapeutics plc.; Agenus Inc.; Akeso Biopharma Co., Ltd.; Amgen Inc.; Aravive; AstraZeneca; Bayer Corporation; Clovis Oncology; Eisai Inc.; Elevar, LLC; EMD Serono, Inc.; F. Hoffmann-La Roche Ltd./Genentech, Inc.; Genmab A/S/Seagen Inc.; The GOG Foundation Inc; Gradalis, Inc.; ImmunoGen, Inc.; Iovance Biotherapeutics, Inc.; Jiangsu Hengrui Pharmaceuticals Co., Ltd.; Karyopharm; Laekna Therapeutics; Merck & Co., Inc.; Mersana Therapeutics; Myriad Genetics, Inc.; Novartis Pharmaceuticals Corporation; Novocure GmbH; OncoC4, Inc.; Panavance Therapeutics Inc.; Pfizer; Pieris Pharmaceuticals, Inc.; Puma Biotechnology, Inc.; Regeneron Pharmaceuticals Inc.; Sorrento Therapeutics, Inc.; TESARO, Inc./GlaxoSmithKline; US Oncology Research, LLC; VBL Therapeutics; Verastem, Inc.; and Zentalis Pharmaceuticals.Grant/Research Support from US Oncology Research, LLC.Speaker for AstraZeneca; Clovis Oncology; Eisai Inc.; F. Hoffmann-La Roche Ltd./Genentech, Inc.; Merck & Co., Inc.; and TESARO, Inc./GlaxoSmithKline.Faculty/PlannerAna Oaknin, MD, PhD, has a financial interest/relationship or affiliation in the form of:Consultant and/or Advisor for Agenus Inc.; AstraZeneca; Clovis Oncology; Corcept Therapeutics; Deciphera Pharmaceuticals; Eisai Co., Ltd.; EMD Serono; Exelisis, Inc.; F. Hoffmann-La Roche; Genmab A/S; GlaxoSmithKline; ImmunoGen, Inc.; iTeos Therapeutics; Merck Sharp & Dohme de Espana SA; Mersana Therapeutics; Novocure GmbH; OncXerna Therapeutics, Inc.; Pharma Mar SA; Regeneron Pharmaceuticals Inc.; Seagen, Inc.; Shattuck Labs, Inc.; and Sutro Biopharma, Inc.Grant/Research Support from AbbVie Deutschland; Advaxis Inc.; Aeterna Zentaris; Amgen Inc.; Aprea Therapeutics AB; Bristol Myers Squibb; Clovis Oncology; Eisai Co., Ltd.; F. Hoffmann-La Roche; ImmunoGen, Inc.; Merck Sharp & Dohme de Espana SA; Millennium Pharmaceuticals Inc.; Pharma Mar SA; Regeneron Pharmaceuticals Inc; and Tesaro.Planning Committee and Reviewer DisclosuresPlanners, independent reviewers, and staff of PVI, PeerView Institute for Medical Education, do not have any relevant financial relationships related to this CE activity unless listed below.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/BVX865. CME/MOC/AAPA/IPCE credit will be available until December 10, 2024.The ABCs of ADCs for Gynecologic Cancer: Expert Insights on Effective Implementation and Practical Tips for Use in Patients With Cervical, Ovarian, or Endometrial Cancer In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Daiichi Sankyo, Inc., Eisai Inc., and Seagen and Genmab.Disclosure PolicyAll relevant conflicts of interest have been mitigated prior to the commencement of the activity.Faculty/Planner DisclosuresChair/PlannerBradley J. Monk, MD, FACS, FACOG, has a financial interest/relationship or affiliation in the form of:Consultant and/or Advisor for Acrivon Therapeutics; Adaptimmune Therapeutics plc.; Agenus Inc.; Akeso Biopharma Co., Ltd.; Amgen Inc.; Aravive; AstraZeneca; Bayer Corporation; Clovis Oncology; Eisai Inc.; Elevar, LLC; EMD Serono, Inc.; F. Hoffmann-La Roche Ltd./Genentech, Inc.; Genmab A/S/Seagen Inc.; The GOG Foundation Inc; Gradalis, Inc.; ImmunoGen, Inc.; Iovance Biotherapeutics, Inc.; Jiangsu Hengrui Pharmaceuticals Co., Ltd.; Karyopharm; Laekna Therapeutics; Merck & Co., Inc.; Mersana Therapeutics; Myriad Genetics, Inc.; Novartis Pharmaceuticals Corporation; Novocure GmbH; OncoC4, Inc.; Panavance Therapeutics Inc.; Pfizer; Pieris Pharmaceuticals, Inc.; Puma Biotechnology, Inc.; Regeneron Pharmaceuticals Inc.; Sorrento Therapeutics, Inc.; TESARO, Inc./GlaxoSmithKline; US Oncology Research, LLC; VBL Therapeutics; Verastem, Inc.; and Zentalis Pharmaceuticals.Grant/Research Support from US Oncology Research, LLC.Speaker for AstraZeneca; Clovis Oncology; Eisai Inc.; F. Hoffmann-La Roche Ltd./Genentech, Inc.; Merck & Co., Inc.; and TESARO, Inc./GlaxoSmithKline.Faculty/PlannerAna Oaknin, MD, PhD, has a financial interest/relationship or affiliation in the form of:Consultant and/or Advisor for Agenus Inc.; AstraZeneca; Clovis Oncology; Corcept Therapeutics; Deciphera Pharmaceuticals; Eisai Co., Ltd.; EMD Serono; Exelisis, Inc.; F. Hoffmann-La Roche; Genmab A/S; GlaxoSmithKline; ImmunoGen, Inc.; iTeos Therapeutics; Merck Sharp & Dohme de Espana SA; Mersana Therapeutics; Novocure GmbH; OncXerna Therapeutics, Inc.; Pharma Mar SA; Regeneron Pharmaceuticals Inc.; Seagen, Inc.; Shattuck Labs, Inc.; and Sutro Biopharma, Inc.Grant/Research Support from AbbVie Deutschland; Advaxis Inc.; Aeterna Zentaris; Amgen Inc.; Aprea Therapeutics AB; Bristol Myers Squibb; Clovis Oncology; Eisai Co., Ltd.; F. Hoffmann-La Roche; ImmunoGen, Inc.; Merck Sharp & Dohme de Espana SA; Millennium Pharmaceuticals Inc.; Pharma Mar SA; Regeneron Pharmaceuticals Inc; and Tesaro.Planning Committee and Reviewer DisclosuresPlanners, independent reviewers, and staff of PVI, PeerView Institute for Medical Education, do not have any relevant financial relationships related to this CE activity unless listed below.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/BVX865. CME/MOC/AAPA/IPCE credit will be available until December 10, 2024.The ABCs of ADCs for Gynecologic Cancer: Expert Insights on Effective Implementation and Practical Tips for Use in Patients With Cervical, Ovarian, or Endometrial Cancer In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent educational grants from AstraZeneca, Daiichi Sankyo, Inc., Eisai Inc., and Seagen and Genmab.Disclosure PolicyAll relevant conflicts of interest have been mitigated prior to the commencement of the activity.Faculty/Planner DisclosuresChair/PlannerBradley J. Monk, MD, FACS, FACOG, has a financial interest/relationship or affiliation in the form of:Consultant and/or Advisor for Acrivon Therapeutics; Adaptimmune Therapeutics plc.; Agenus Inc.; Akeso Biopharma Co., Ltd.; Amgen Inc.; Aravive; AstraZeneca; Bayer Corporation; Clovis Oncology; Eisai Inc.; Elevar, LLC; EMD Serono, Inc.; F. Hoffmann-La Roche Ltd./Genentech, Inc.; Genmab A/S/Seagen Inc.; The GOG Foundation Inc; Gradalis, Inc.; ImmunoGen, Inc.; Iovance Biotherapeutics, Inc.; Jiangsu Hengrui Pharmaceuticals Co., Ltd.; Karyopharm; Laekna Therapeutics; Merck & Co., Inc.; Mersana Therapeutics; Myriad Genetics, Inc.; Novartis Pharmaceuticals Corporation; Novocure GmbH; OncoC4, Inc.; Panavance Therapeutics Inc.; Pfizer; Pieris Pharmaceuticals, Inc.; Puma Biotechnology, Inc.; Regeneron Pharmaceuticals Inc.; Sorrento Therapeutics, Inc.; TESARO, Inc./GlaxoSmithKline; US Oncology Research, LLC; VBL Therapeutics; Verastem, Inc.; and Zentalis Pharmaceuticals.Grant/Research Support from US Oncology Research, LLC.Speaker for AstraZeneca; Clovis Oncology; Eisai Inc.; F. Hoffmann-La Roche Ltd./Genentech, Inc.; Merck & Co., Inc.; and TESARO, Inc./GlaxoSmithKline.Faculty/PlannerAna Oaknin, MD, PhD, has a financial interest/relationship or affiliation in the form of:Consultant and/or Advisor for Agenus Inc.; AstraZeneca; Clovis Oncology; Corcept Therapeutics; Deciphera Pharmaceuticals; Eisai Co., Ltd.; EMD Serono; Exelisis, Inc.; F. Hoffmann-La Roche; Genmab A/S; GlaxoSmithKline; ImmunoGen, Inc.; iTeos Therapeutics; Merck Sharp & Dohme de Espana SA; Mersana Therapeutics; Novocure GmbH; OncXerna Therapeutics, Inc.; Pharma Mar SA; Regeneron Pharmaceuticals Inc.; Seagen, Inc.; Shattuck Labs, Inc.; and Sutro Biopharma, Inc.Grant/Research Support from AbbVie Deutschland; Advaxis Inc.; Aeterna Zentaris; Amgen Inc.; Aprea Therapeutics AB; Bristol Myers Squibb; Clovis Oncology; Eisai Co., Ltd.; F. Hoffmann-La Roche; ImmunoGen, Inc.; Merck Sharp & Dohme de Espana SA; Millennium Pharmaceuticals Inc.; Pharma Mar SA; Regeneron Pharmaceuticals Inc; and Tesaro.Planning Committee and Reviewer DisclosuresPlanners, independent reviewers, and staff of PVI, PeerView Institute for Medical Education, do not have any relevant financial relationships related to this CE activity unless listed below.

Featuring perspectives from Prof Mitesh J Borad, Dr Anthony El-Khoueiry, Dr Christopher R Flowers, Dr Sara A Hurvitz, Dr Thomas E Hutson, Dr Amrita Krishnan, Dr Ann S LaCasce, Dr Heather McArthur, Dr Bradley J Monk, Dr Kathleen N Moore, Dr Robert Z Orlowski and Dr Guru P Sonpavde, moderated by Dr Neil Love, co-moderated by Dr Stephen “Fred” Divers, including the following topics: Introduction (0:00) Biliary Tract and Pancreatic Cancer — Mitesh J Borad, MD (3:42) Hepatocellular Carcinoma — Anthony El-Khoueiry, MD (33:25) CME information and select publications

Featuring perspectives from Prof Mitesh J Borad, Dr Anthony El-Khoueiry, Dr Christopher R Flowers, Dr Sara A Hurvitz, Dr Thomas E Hutson, Dr Amrita Krishnan, Dr Ann S LaCasce, Dr Heather McArthur, Dr Bradley J Monk, Dr Kathleen N Moore, Dr Robert Z Orlowski and Dr Guru P Sonpavde, moderated by Dr Neil Love, co-moderated by Dr Stephen “Fred” Divers, including the following topics: Introduction (0:00) Triple-Negative Breast Cancer — Heather McArthur, MD, MPH (6:59) HER2-Positive Breast Cancer — Sara A Hurvitz, MD, FACP (44:04) CME information and select publications

Featuring perspectives from Prof Mitesh J Borad, Dr Anthony El-Khoueiry, Dr Christopher R Flowers, Dr Sara A Hurvitz, Dr Thomas E Hutson, Dr Amrita Krishnan, Dr Ann S LaCasce, Dr Heather McArthur, Dr Bradley J Monk, Dr Kathleen N Moore, Dr Robert Z Orlowski and Dr Guru P Sonpavde, moderated by Dr Neil Love, co-moderated by Dr Stephen “Fred” Divers, including the following topics: Introduction (0:00) Diffuse Large B-Cell Lymphoma and Hodgkin Lymphoma — Ann S LaCasce, MD, MMSc (8:26) Follicular Lymphoma and Mantle Cell Lymphoma — Christopher R Flowers, MD, MS (42:55) CME information and select publications

Featuring perspectives from Prof Mitesh J Borad, Dr Anthony El-Khoueiry, Dr Christopher R Flowers, Dr Sara A Hurvitz, Dr Thomas E Hutson, Dr Amrita Krishnan, Dr Ann S LaCasce, Dr Heather McArthur, Dr Bradley J Monk, Dr Kathleen N Moore, Dr Robert Z Orlowski and Dr Guru P Sonpavde, moderated by Dr Neil Love, co-moderated by Dr Stephen “Fred” Divers, including the following topics: Introduction (0:00) Ovarian Cancer — Kathleen N Moore, MD, MS (4:14) Endometrial and Cervical Cancers — Bradley J Monk, MD (41:09) CME information and select publications

Featuring perspectives from Prof Mitesh J Borad, Dr Anthony El-Khoueiry, Dr Christopher R Flowers, Dr Sara A Hurvitz, Dr Thomas E Hutson, Dr Amrita Krishnan, Dr Ann S LaCasce, Dr Heather McArthur, Dr Bradley J Monk, Dr Kathleen N Moore, Dr Robert Z Orlowski and Dr Guru P Sonpavde, moderated by Dr Neil Love, co-moderated by Dr Stephen “Fred” Divers, including the following topics: Introduction (0:00) Optimizing the Current Management of Multiple Myeloma — Robert Z Orlowski, MD, PhD (3:44) CAR (Chimeric Antigen Receptor) T-Cell Therapy, Bispecific Antibodies and Other Novel Approaches — Amrita Krishnan, MD (32:37) CME information and select publications

Featuring perspectives from Prof Mitesh J Borad, Dr Anthony El-Khoueiry, Dr Christopher R Flowers, Dr Sara A Hurvitz, Dr Thomas E Hutson, Dr Amrita Krishnan, Dr Ann S LaCasce, Dr Heather McArthur, Dr Bradley J Monk, Dr Kathleen N Moore, Dr Robert Z Orlowski and Dr Guru P Sonpavde, moderated by Dr Neil Love, co-moderated by Dr Stephen “Fred” Divers, including the following topics: Introduction (0:00) Renal Cell Carcinoma — Thomas E Hutson, DO, PharmD (6:19) Urothelial Bladder Cancer — Guru P Sonpavde, MD (34:59) CME information and select publications  

Last week, the European Society of Medical Oncology (EMSO) held their annual Congress in Madrid. The conference brought together cancer researchers from around the globe, who presented their clinical trial data — some of which has the potential to change the way cancers are treated.  For example, the Food and Drug Administration (FDA) approves therapies based on study data that proves that the regimen in question is safe, effective and superior to what is currently being used in that indication. While we don't have a crystal ball and can't say for sure if and when the FDA will approve a regimen, we can reflect on data presented at ESMO that we know the agency is considering and give our audience some potential oncology approvals that they should look out for.  Welireg Outperforms Afinitor in Advanced Clear Cell Kidney Cancer The FDA is currently reviewing the phase 3 LIFESPARK-005 trial, comparing Welireg to Afinitor for patients with pretreated advanced clear cell renal carcinoma. Data from LIFESPARK-005, which were presented at the ESMO Congress, showed that Welireg outperformed Afinitor when it came to progression-free survival (that's the time a patient lives after treatment without their disease worsening) and objective response rate (which describes the percentage of patients whose disease shrinks or disappears from treatment). However, there was no significant difference in overall survival (time from treatment unitl death of any cause) observed between the Welireg and Afinitor groups. The FDA is set to make their decision on this Welireg indication by Jan. 17, 2024.  Keytruda Plus Chemoradiotherapy Bests Standard of Care in Advanced Cervical Cancer  Also on the FDA's docket for review is findings from the phase 3 KEYNOTE-A18 trial, investigating the addition of Keytruda to external beam radiotherapy — known as EBRT — and concurrent chemotherapy and followed by brachytherapy, for the treatment of patients with newly diagnosed, high-risk locally advanced cervical cancer. Study findings, which were presented at the ESMO Congress, showed that adding the immunotherapy agent to the regimen improved progression-free survival, overall survival and response rates. One expert, Dr. Bradley J. Monk, even commented, “This is a celebration for patients because we're challenging a treatment paradigm that has stood for more than two decades.” The FDA stated that it plans to make its approval decision of Keytruda in this indication by Jan. 20, 2024.  Data Supporting FDA Approval of Pre- and Postsurgical Keytruda for Advanced Lung Cancer Presented Days before ESMO, the FDA also approved Keytruda for the pre- and postsurgical treatment of patients with resectable (able to be removed via surgery) stage 2, 3A or 3B non-small cell lung cancer (NSCLC).  The approval is based off findings from the phase 3 KEYNOTE-671 trial, which compared treatment with presurgical Keytruda plus chemotherapy followed by postsurgical Keytruda against presurgical placebo plus chemotherapy, followed by placebo. According to the FDA, overall survival (the time from treatment until death of any cause) was not reached in the Keytruda group, meaning not enough patients in that cohort had died to determine an average time until death. The median overall survival time was 52.4 months in the placebo group. Study findings presented at EMSO showed improvements in event-free survival (the time a patient lives without any disease-related occurrences, such as a recurrence/relapse or death), which was also not yet reached among patients in the Keytruda arm of the study. For more news on cancer updates, research and education, don't forget to subscribe to CURE®'s newsletters here.

Featuring perspectives from Dr Bradley J Monk and Dr Matthew A Powell moderated by Dr Neil Love. Produced by Research to Practice. CME information and select publications here (http://www.researchtopractice.com/PostSGO23Endometrial).

Featuring perspectives from Dr Bradley J Monk and Dr Matthew A Powell, moderated by Dr Neil Love.

Featuring perspectives from Dr Bradley J Monk and Dr Matthew A Powell, including the following topics: Introduction (0:00) First-Line Therapy for Advanced Endometrial Cancer (EC) — Dr Powell (7:32) Current Options for Relapsed EC; Promising Investigational Agents and Strategies — Dr Monk (32:39) Clinical Investigator Survey (43:41) CME information and select publications

In this episode of the IJGC podcast, Editor-in-Chief Dr. Pedro Ramirez is joined by Professor Bradley J. Monk to discuss the ATHENA-MONO clinical trial. Prof. Monk is an international thought leader and clinical trialist who has developed and advocated for maintenance treatment in newly diagnosed advanced and recurrent ovarian cancer. ATHENA-MONO represents his fifth positive randomized phase 3 trial studying maintenance treatment and adds confidence to this efficacious and tolerable paradigm changing opportunity for all patients regardless of the molecular genotype (allcomers). Highlights: - Maintenance therapy is now the global standard of care in patients with advanced or recurrent epithelial ovarian cancer. This can include a PAPP inhibitor, bevacizumab, or the combination. - Maintenance treatment is efficacious in all molecular subgroups and is tolerable without an impairment in the quality of life. - Payers acknowledge the value of maintenance treatment as do consensus guidelines.

In this episode of Meeting Mic, we bring you pearls and perspectives from the 2022 ASCO Annual Meeting, as well as Healio's top headlines from the meeting. Stephen M. Ansell, MD, PhD, discusses efforts to identify new upfront treatment regimens to help extend OS in patients with relapsed or refractory classical Hodgkin lymphoma. :25 Lorenzo Cohen, PhD, shares his thought on the impact of acupuncture regimens on xerostomia and patients' quality of life. 5:26 Bradley J. Monk, MD, discusses the results of a study on the use of rucaparib monotherapy among women with advanced ovarian cancer 10:37 Christopher Manz, MD, MSHP, provides an overview of the results of the randomized PROStep trial, which assessed whether remote patient-reported symptoms and passive activity monitoring could improve patient-clinician communication about symptoms and functional status of patients with cancer. 18:09 Luke Maese, DO, discusses the results of the Children's Oncology Group AALL1931 study, its rationale, the potential implications of the findings and the questions that must be addressed in future research. 21:04     Read the full coverage here: https://www.healio.com/news/hematology-oncology/20220603/firstline-brentuximab-vedotin-regimen-extends-os-in-advanced-classical-hodgkin-lymphoma https://www.healio.com/news/hematology-oncology/20220609/acupuncture-benefits-patients-with-radiationinduced-xerostomia https://www.healio.com/news/hematology-oncology/20220606/rucaparib-shows-efficacy-as-firstline-maintenance-therapy-in-ovarian-cancer https://www.healio.com/news/hematology-oncology/20220610/more-work-to-do-in-oncology-to-collect-useful-data-about-symptoms-functional-status https://www.healio.com/news/hematology-oncology/20220611/intramuscular-recombinant-erwinia-asparaginase-active-safe-in-leukemia-lymphoma-subsets Dostarlimab shows efficacy as curative-intent treatment in rectal cancer subset Source: Cercek A, et al. Abstract LBA5. Presented at: ASCO Annual Meeting; June 3-7, 2022; Chicago. Trastuzumab deruxtecan extends survival in HER2-low metastatic breast cancer Source: Modi S, et al. Abstract LBA3. Presented at: ASCO Annual Meeting; June 3-7, 2022; Chicago. Disclosures: Ansell reports research funding to his institution from ADC Therapeutics; Affimed Therapeutics, AI Therapeutics, Bristol Myers Squibb, Regeneron, Seagen and Trillium Therapeutics, and honoraria from Research to Practice and WebMD. Cohen reports no relevant financial disclosures. Monk reports relationships with Clovis Oncology, Merck, Roche/Genentech and several other pharmaceutical companies. Manz reports no relevant financial disclosures. Maese reports consultant and speakers bureau roles with Jazz Pharmaceuticals.

Go online to PeerView.com/YWA860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Are you optimizing the care of your patients with ovarian cancer with poly (ADP-ribose) polymerase (PARP) inhibitors and novel therapies such as tumor treating fields (TTFields)? If you are like many oncologists, gynecologists, and other clinicians involved in the treatment of patients with ovarian cancer, you may be struggling to understand which patients will benefit from treatment with these newer approaches. Join PeerView for an educational activity designed to provide busy healthcare practitioners with the information they need to use these treatments in clinical practice. Our expert faculty will provide an in-depth look at recent clinical evidence and ongoing research on PARP inhibitors, TTFields, and other novel strategies in ovarian cancer and practical guidance, drawn from their own experience, on incorporating new treatments, including through clinical trial enrollment and in combination with other modalities, into individualized treatment plans. Hear the latest on diagnostic testing for relevant biomarkers, recommendations for collaborative AE management, opportunities for clinical trial enrollment, and strategies for patient/caregiver education to help patients become well-informed participants in their own care. Upon completion of this activity, participants should be better able to: Integrate germline and tumor genetic testing into the workup of patients with advanced ovarian cancer to inform therapeutic decision-making, Incorporate PARP inhibitors and other novel treatments into the management of patients with advanced ovarian cancer, including within the context of clinical trials, considering the current clinical evidence, guideline recommendations, and patient needs and preferences, Develop practical strategies to recognize and manage AEs related to PARP inhibitor use and other novel approaches in patients with ovarian cancer, particularly in the long-term maintenance setting.

Go online to PeerView.com/YWA860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Are you optimizing the care of your patients with ovarian cancer with poly (ADP-ribose) polymerase (PARP) inhibitors and novel therapies such as tumor treating fields (TTFields)? If you are like many oncologists, gynecologists, and other clinicians involved in the treatment of patients with ovarian cancer, you may be struggling to understand which patients will benefit from treatment with these newer approaches. Join PeerView for an educational activity designed to provide busy healthcare practitioners with the information they need to use these treatments in clinical practice. Our expert faculty will provide an in-depth look at recent clinical evidence and ongoing research on PARP inhibitors, TTFields, and other novel strategies in ovarian cancer and practical guidance, drawn from their own experience, on incorporating new treatments, including through clinical trial enrollment and in combination with other modalities, into individualized treatment plans. Hear the latest on diagnostic testing for relevant biomarkers, recommendations for collaborative AE management, opportunities for clinical trial enrollment, and strategies for patient/caregiver education to help patients become well-informed participants in their own care. Upon completion of this activity, participants should be better able to: Integrate germline and tumor genetic testing into the workup of patients with advanced ovarian cancer to inform therapeutic decision-making, Incorporate PARP inhibitors and other novel treatments into the management of patients with advanced ovarian cancer, including within the context of clinical trials, considering the current clinical evidence, guideline recommendations, and patient needs and preferences, Develop practical strategies to recognize and manage AEs related to PARP inhibitor use and other novel approaches in patients with ovarian cancer, particularly in the long-term maintenance setting.

Go online to PeerView.com/YWA860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Are you optimizing the care of your patients with ovarian cancer with poly (ADP-ribose) polymerase (PARP) inhibitors and novel therapies such as tumor treating fields (TTFields)? If you are like many oncologists, gynecologists, and other clinicians involved in the treatment of patients with ovarian cancer, you may be struggling to understand which patients will benefit from treatment with these newer approaches. Join PeerView for an educational activity designed to provide busy healthcare practitioners with the information they need to use these treatments in clinical practice. Our expert faculty will provide an in-depth look at recent clinical evidence and ongoing research on PARP inhibitors, TTFields, and other novel strategies in ovarian cancer and practical guidance, drawn from their own experience, on incorporating new treatments, including through clinical trial enrollment and in combination with other modalities, into individualized treatment plans. Hear the latest on diagnostic testing for relevant biomarkers, recommendations for collaborative AE management, opportunities for clinical trial enrollment, and strategies for patient/caregiver education to help patients become well-informed participants in their own care. Upon completion of this activity, participants should be better able to: Integrate germline and tumor genetic testing into the workup of patients with advanced ovarian cancer to inform therapeutic decision-making, Incorporate PARP inhibitors and other novel treatments into the management of patients with advanced ovarian cancer, including within the context of clinical trials, considering the current clinical evidence, guideline recommendations, and patient needs and preferences, Develop practical strategies to recognize and manage AEs related to PARP inhibitor use and other novel approaches in patients with ovarian cancer, particularly in the long-term maintenance setting.

Go online to PeerView.com/YWA860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Are you optimizing the care of your patients with ovarian cancer with poly (ADP-ribose) polymerase (PARP) inhibitors and novel therapies such as tumor treating fields (TTFields)? If you are like many oncologists, gynecologists, and other clinicians involved in the treatment of patients with ovarian cancer, you may be struggling to understand which patients will benefit from treatment with these newer approaches. Join PeerView for an educational activity designed to provide busy healthcare practitioners with the information they need to use these treatments in clinical practice. Our expert faculty will provide an in-depth look at recent clinical evidence and ongoing research on PARP inhibitors, TTFields, and other novel strategies in ovarian cancer and practical guidance, drawn from their own experience, on incorporating new treatments, including through clinical trial enrollment and in combination with other modalities, into individualized treatment plans. Hear the latest on diagnostic testing for relevant biomarkers, recommendations for collaborative AE management, opportunities for clinical trial enrollment, and strategies for patient/caregiver education to help patients become well-informed participants in their own care. Upon completion of this activity, participants should be better able to: Integrate germline and tumor genetic testing into the workup of patients with advanced ovarian cancer to inform therapeutic decision-making, Incorporate PARP inhibitors and other novel treatments into the management of patients with advanced ovarian cancer, including within the context of clinical trials, considering the current clinical evidence, guideline recommendations, and patient needs and preferences, Develop practical strategies to recognize and manage AEs related to PARP inhibitor use and other novel approaches in patients with ovarian cancer, particularly in the long-term maintenance setting.

Go online to PeerView.com/YWA860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Are you optimizing the care of your patients with ovarian cancer with poly (ADP-ribose) polymerase (PARP) inhibitors and novel therapies such as tumor treating fields (TTFields)? If you are like many oncologists, gynecologists, and other clinicians involved in the treatment of patients with ovarian cancer, you may be struggling to understand which patients will benefit from treatment with these newer approaches. Join PeerView for an educational activity designed to provide busy healthcare practitioners with the information they need to use these treatments in clinical practice. Our expert faculty will provide an in-depth look at recent clinical evidence and ongoing research on PARP inhibitors, TTFields, and other novel strategies in ovarian cancer and practical guidance, drawn from their own experience, on incorporating new treatments, including through clinical trial enrollment and in combination with other modalities, into individualized treatment plans. Hear the latest on diagnostic testing for relevant biomarkers, recommendations for collaborative AE management, opportunities for clinical trial enrollment, and strategies for patient/caregiver education to help patients become well-informed participants in their own care. Upon completion of this activity, participants should be better able to: Integrate germline and tumor genetic testing into the workup of patients with advanced ovarian cancer to inform therapeutic decision-making, Incorporate PARP inhibitors and other novel treatments into the management of patients with advanced ovarian cancer, including within the context of clinical trials, considering the current clinical evidence, guideline recommendations, and patient needs and preferences, Develop practical strategies to recognize and manage AEs related to PARP inhibitor use and other novel approaches in patients with ovarian cancer, particularly in the long-term maintenance setting.

Go online to PeerView.com/YWA860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Are you optimizing the care of your patients with ovarian cancer with poly (ADP-ribose) polymerase (PARP) inhibitors and novel therapies such as tumor treating fields (TTFields)? If you are like many oncologists, gynecologists, and other clinicians involved in the treatment of patients with ovarian cancer, you may be struggling to understand which patients will benefit from treatment with these newer approaches. Join PeerView for an educational activity designed to provide busy healthcare practitioners with the information they need to use these treatments in clinical practice. Our expert faculty will provide an in-depth look at recent clinical evidence and ongoing research on PARP inhibitors, TTFields, and other novel strategies in ovarian cancer and practical guidance, drawn from their own experience, on incorporating new treatments, including through clinical trial enrollment and in combination with other modalities, into individualized treatment plans. Hear the latest on diagnostic testing for relevant biomarkers, recommendations for collaborative AE management, opportunities for clinical trial enrollment, and strategies for patient/caregiver education to help patients become well-informed participants in their own care. Upon completion of this activity, participants should be better able to: Integrate germline and tumor genetic testing into the workup of patients with advanced ovarian cancer to inform therapeutic decision-making, Incorporate PARP inhibitors and other novel treatments into the management of patients with advanced ovarian cancer, including within the context of clinical trials, considering the current clinical evidence, guideline recommendations, and patient needs and preferences, Develop practical strategies to recognize and manage AEs related to PARP inhibitor use and other novel approaches in patients with ovarian cancer, particularly in the long-term maintenance setting.

Go online to PeerView.com/YWA860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Are you optimizing the care of your patients with ovarian cancer with poly (ADP-ribose) polymerase (PARP) inhibitors and novel therapies such as tumor treating fields (TTFields)? If you are like many oncologists, gynecologists, and other clinicians involved in the treatment of patients with ovarian cancer, you may be struggling to understand which patients will benefit from treatment with these newer approaches. Join PeerView for an educational activity designed to provide busy healthcare practitioners with the information they need to use these treatments in clinical practice. Our expert faculty will provide an in-depth look at recent clinical evidence and ongoing research on PARP inhibitors, TTFields, and other novel strategies in ovarian cancer and practical guidance, drawn from their own experience, on incorporating new treatments, including through clinical trial enrollment and in combination with other modalities, into individualized treatment plans. Hear the latest on diagnostic testing for relevant biomarkers, recommendations for collaborative AE management, opportunities for clinical trial enrollment, and strategies for patient/caregiver education to help patients become well-informed participants in their own care. Upon completion of this activity, participants should be better able to: Integrate germline and tumor genetic testing into the workup of patients with advanced ovarian cancer to inform therapeutic decision-making, Incorporate PARP inhibitors and other novel treatments into the management of patients with advanced ovarian cancer, including within the context of clinical trials, considering the current clinical evidence, guideline recommendations, and patient needs and preferences, Develop practical strategies to recognize and manage AEs related to PARP inhibitor use and other novel approaches in patients with ovarian cancer, particularly in the long-term maintenance setting.

Go online to PeerView.com/YWA860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Are you optimizing the care of your patients with ovarian cancer with poly (ADP-ribose) polymerase (PARP) inhibitors and novel therapies such as tumor treating fields (TTFields)? If you are like many oncologists, gynecologists, and other clinicians involved in the treatment of patients with ovarian cancer, you may be struggling to understand which patients will benefit from treatment with these newer approaches. Join PeerView for an educational activity designed to provide busy healthcare practitioners with the information they need to use these treatments in clinical practice. Our expert faculty will provide an in-depth look at recent clinical evidence and ongoing research on PARP inhibitors, TTFields, and other novel strategies in ovarian cancer and practical guidance, drawn from their own experience, on incorporating new treatments, including through clinical trial enrollment and in combination with other modalities, into individualized treatment plans. Hear the latest on diagnostic testing for relevant biomarkers, recommendations for collaborative AE management, opportunities for clinical trial enrollment, and strategies for patient/caregiver education to help patients become well-informed participants in their own care. Upon completion of this activity, participants should be better able to: Integrate germline and tumor genetic testing into the workup of patients with advanced ovarian cancer to inform therapeutic decision-making, Incorporate PARP inhibitors and other novel treatments into the management of patients with advanced ovarian cancer, including within the context of clinical trials, considering the current clinical evidence, guideline recommendations, and patient needs and preferences, Develop practical strategies to recognize and manage AEs related to PARP inhibitor use and other novel approaches in patients with ovarian cancer, particularly in the long-term maintenance setting.

Go online to PeerView.com/CHG860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. For clinicians managing patients with advanced ovarian cancer, the use of poly (ADP-ribose) polymerase (PARP) inhibitors and new treatment modalities such as tumor treating fields (TTFields) represents an important opportunity to provide personalized medicine. With a key role in the treatment and maintenance of recurrent disease, as well as in first-line maintenance of newly diagnosed disease, PARP inhibitors are indicated by the FDA for use in patients with BRCA-deficient tumors, homologous recombination deficient (HRD) tumors, and biomarker wild-type tumors. PARP inhibitors are also being actively researched in combination with other systemic agents, including targeted therapies, chemotherapy, and immunotherapy, in an effort to overcome PARP resistance and exploit additive efficacy. Already approved in glioblastoma and mesothelioma, TTFields, a new modality that targets solid tumors via alternating electric fields, is paving the way for improved outcomes in a variety of cancers, including ovarian. In an engaging new educational activity, PeerView's experts will present a series of MasterClasses featuring thorough reviews of the latest efficacy and safety data on current and emerging PARP inhibitor–based and novel therapeutic strategies for the treatment of patients with advanced ovarian cancer in a variety of settings. Drawing from their own practice, the experts will then provide guidance on using these agents—alone, in combination with other agents, and in the context of a clinical trial—with a focus on understanding the role of genetic testing, recognizing and managing adverse events, and working within a multidisciplinary care team to improve outcomes for patients. Upon completion of this accredited CE activity, participants should be better able to: Cite the mechanistic rationale and latest clinical evidence supporting the use of current and emerging PARP inhibitor–based strategies in patients with newly diagnosed and recurrent advanced ovarian cancer, Integrate germline and tumor genetic testing into the workup of patients with advanced ovarian cancer to inform therapeutic decision-making, Incorporate PARP inhibitors and other novel multimodal approaches into the management of patients with advanced ovarian cancer, including within the context of clinical trials, based on the current clinical evidence, guideline recommendations, and patient needs and preferences, Develop practical strategies to recognize and manage adverse events related to the use of PARP inhibitors, particularly with long-term use such as in maintenance settings, in patients with ovarian cancer.

Go online to PeerView.com/CHG860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. For clinicians managing patients with advanced ovarian cancer, the use of poly (ADP-ribose) polymerase (PARP) inhibitors and new treatment modalities such as tumor treating fields (TTFields) represents an important opportunity to provide personalized medicine. With a key role in the treatment and maintenance of recurrent disease, as well as in first-line maintenance of newly diagnosed disease, PARP inhibitors are indicated by the FDA for use in patients with BRCA-deficient tumors, homologous recombination deficient (HRD) tumors, and biomarker wild-type tumors. PARP inhibitors are also being actively researched in combination with other systemic agents, including targeted therapies, chemotherapy, and immunotherapy, in an effort to overcome PARP resistance and exploit additive efficacy. Already approved in glioblastoma and mesothelioma, TTFields, a new modality that targets solid tumors via alternating electric fields, is paving the way for improved outcomes in a variety of cancers, including ovarian. In an engaging new educational activity, PeerView's experts will present a series of MasterClasses featuring thorough reviews of the latest efficacy and safety data on current and emerging PARP inhibitor–based and novel therapeutic strategies for the treatment of patients with advanced ovarian cancer in a variety of settings. Drawing from their own practice, the experts will then provide guidance on using these agents—alone, in combination with other agents, and in the context of a clinical trial—with a focus on understanding the role of genetic testing, recognizing and managing adverse events, and working within a multidisciplinary care team to improve outcomes for patients. Upon completion of this accredited CE activity, participants should be better able to: Cite the mechanistic rationale and latest clinical evidence supporting the use of current and emerging PARP inhibitor–based strategies in patients with newly diagnosed and recurrent advanced ovarian cancer, Integrate germline and tumor genetic testing into the workup of patients with advanced ovarian cancer to inform therapeutic decision-making, Incorporate PARP inhibitors and other novel multimodal approaches into the management of patients with advanced ovarian cancer, including within the context of clinical trials, based on the current clinical evidence, guideline recommendations, and patient needs and preferences, Develop practical strategies to recognize and manage adverse events related to the use of PARP inhibitors, particularly with long-term use such as in maintenance settings, in patients with ovarian cancer.

Go online to PeerView.com/CHG860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. For clinicians managing patients with advanced ovarian cancer, the use of poly (ADP-ribose) polymerase (PARP) inhibitors and new treatment modalities such as tumor treating fields (TTFields) represents an important opportunity to provide personalized medicine. With a key role in the treatment and maintenance of recurrent disease, as well as in first-line maintenance of newly diagnosed disease, PARP inhibitors are indicated by the FDA for use in patients with BRCA-deficient tumors, homologous recombination deficient (HRD) tumors, and biomarker wild-type tumors. PARP inhibitors are also being actively researched in combination with other systemic agents, including targeted therapies, chemotherapy, and immunotherapy, in an effort to overcome PARP resistance and exploit additive efficacy. Already approved in glioblastoma and mesothelioma, TTFields, a new modality that targets solid tumors via alternating electric fields, is paving the way for improved outcomes in a variety of cancers, including ovarian. In an engaging new educational activity, PeerView's experts will present a series of MasterClasses featuring thorough reviews of the latest efficacy and safety data on current and emerging PARP inhibitor–based and novel therapeutic strategies for the treatment of patients with advanced ovarian cancer in a variety of settings. Drawing from their own practice, the experts will then provide guidance on using these agents—alone, in combination with other agents, and in the context of a clinical trial—with a focus on understanding the role of genetic testing, recognizing and managing adverse events, and working within a multidisciplinary care team to improve outcomes for patients. Upon completion of this accredited CE activity, participants should be better able to: Cite the mechanistic rationale and latest clinical evidence supporting the use of current and emerging PARP inhibitor–based strategies in patients with newly diagnosed and recurrent advanced ovarian cancer, Integrate germline and tumor genetic testing into the workup of patients with advanced ovarian cancer to inform therapeutic decision-making, Incorporate PARP inhibitors and other novel multimodal approaches into the management of patients with advanced ovarian cancer, including within the context of clinical trials, based on the current clinical evidence, guideline recommendations, and patient needs and preferences, Develop practical strategies to recognize and manage adverse events related to the use of PARP inhibitors, particularly with long-term use such as in maintenance settings, in patients with ovarian cancer.

Go online to PeerView.com/CHG860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. For clinicians managing patients with advanced ovarian cancer, the use of poly (ADP-ribose) polymerase (PARP) inhibitors and new treatment modalities such as tumor treating fields (TTFields) represents an important opportunity to provide personalized medicine. With a key role in the treatment and maintenance of recurrent disease, as well as in first-line maintenance of newly diagnosed disease, PARP inhibitors are indicated by the FDA for use in patients with BRCA-deficient tumors, homologous recombination deficient (HRD) tumors, and biomarker wild-type tumors. PARP inhibitors are also being actively researched in combination with other systemic agents, including targeted therapies, chemotherapy, and immunotherapy, in an effort to overcome PARP resistance and exploit additive efficacy. Already approved in glioblastoma and mesothelioma, TTFields, a new modality that targets solid tumors via alternating electric fields, is paving the way for improved outcomes in a variety of cancers, including ovarian. In an engaging new educational activity, PeerView's experts will present a series of MasterClasses featuring thorough reviews of the latest efficacy and safety data on current and emerging PARP inhibitor–based and novel therapeutic strategies for the treatment of patients with advanced ovarian cancer in a variety of settings. Drawing from their own practice, the experts will then provide guidance on using these agents—alone, in combination with other agents, and in the context of a clinical trial—with a focus on understanding the role of genetic testing, recognizing and managing adverse events, and working within a multidisciplinary care team to improve outcomes for patients. Upon completion of this accredited CE activity, participants should be better able to: Cite the mechanistic rationale and latest clinical evidence supporting the use of current and emerging PARP inhibitor–based strategies in patients with newly diagnosed and recurrent advanced ovarian cancer, Integrate germline and tumor genetic testing into the workup of patients with advanced ovarian cancer to inform therapeutic decision-making, Incorporate PARP inhibitors and other novel multimodal approaches into the management of patients with advanced ovarian cancer, including within the context of clinical trials, based on the current clinical evidence, guideline recommendations, and patient needs and preferences, Develop practical strategies to recognize and manage adverse events related to the use of PARP inhibitors, particularly with long-term use such as in maintenance settings, in patients with ovarian cancer.

Go online to PeerView.com/CHG860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. For clinicians managing patients with advanced ovarian cancer, the use of poly (ADP-ribose) polymerase (PARP) inhibitors and new treatment modalities such as tumor treating fields (TTFields) represents an important opportunity to provide personalized medicine. With a key role in the treatment and maintenance of recurrent disease, as well as in first-line maintenance of newly diagnosed disease, PARP inhibitors are indicated by the FDA for use in patients with BRCA-deficient tumors, homologous recombination deficient (HRD) tumors, and biomarker wild-type tumors. PARP inhibitors are also being actively researched in combination with other systemic agents, including targeted therapies, chemotherapy, and immunotherapy, in an effort to overcome PARP resistance and exploit additive efficacy. Already approved in glioblastoma and mesothelioma, TTFields, a new modality that targets solid tumors via alternating electric fields, is paving the way for improved outcomes in a variety of cancers, including ovarian. In an engaging new educational activity, PeerView's experts will present a series of MasterClasses featuring thorough reviews of the latest efficacy and safety data on current and emerging PARP inhibitor–based and novel therapeutic strategies for the treatment of patients with advanced ovarian cancer in a variety of settings. Drawing from their own practice, the experts will then provide guidance on using these agents—alone, in combination with other agents, and in the context of a clinical trial—with a focus on understanding the role of genetic testing, recognizing and managing adverse events, and working within a multidisciplinary care team to improve outcomes for patients. Upon completion of this accredited CE activity, participants should be better able to: Cite the mechanistic rationale and latest clinical evidence supporting the use of current and emerging PARP inhibitor–based strategies in patients with newly diagnosed and recurrent advanced ovarian cancer, Integrate germline and tumor genetic testing into the workup of patients with advanced ovarian cancer to inform therapeutic decision-making, Incorporate PARP inhibitors and other novel multimodal approaches into the management of patients with advanced ovarian cancer, including within the context of clinical trials, based on the current clinical evidence, guideline recommendations, and patient needs and preferences, Develop practical strategies to recognize and manage adverse events related to the use of PARP inhibitors, particularly with long-term use such as in maintenance settings, in patients with ovarian cancer.

Go online to PeerView.com/CHG860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. For clinicians managing patients with advanced ovarian cancer, the use of poly (ADP-ribose) polymerase (PARP) inhibitors and new treatment modalities such as tumor treating fields (TTFields) represents an important opportunity to provide personalized medicine. With a key role in the treatment and maintenance of recurrent disease, as well as in first-line maintenance of newly diagnosed disease, PARP inhibitors are indicated by the FDA for use in patients with BRCA-deficient tumors, homologous recombination deficient (HRD) tumors, and biomarker wild-type tumors. PARP inhibitors are also being actively researched in combination with other systemic agents, including targeted therapies, chemotherapy, and immunotherapy, in an effort to overcome PARP resistance and exploit additive efficacy. Already approved in glioblastoma and mesothelioma, TTFields, a new modality that targets solid tumors via alternating electric fields, is paving the way for improved outcomes in a variety of cancers, including ovarian. In an engaging new educational activity, PeerView's experts will present a series of MasterClasses featuring thorough reviews of the latest efficacy and safety data on current and emerging PARP inhibitor–based and novel therapeutic strategies for the treatment of patients with advanced ovarian cancer in a variety of settings. Drawing from their own practice, the experts will then provide guidance on using these agents—alone, in combination with other agents, and in the context of a clinical trial—with a focus on understanding the role of genetic testing, recognizing and managing adverse events, and working within a multidisciplinary care team to improve outcomes for patients. Upon completion of this accredited CE activity, participants should be better able to: Cite the mechanistic rationale and latest clinical evidence supporting the use of current and emerging PARP inhibitor–based strategies in patients with newly diagnosed and recurrent advanced ovarian cancer, Integrate germline and tumor genetic testing into the workup of patients with advanced ovarian cancer to inform therapeutic decision-making, Incorporate PARP inhibitors and other novel multimodal approaches into the management of patients with advanced ovarian cancer, including within the context of clinical trials, based on the current clinical evidence, guideline recommendations, and patient needs and preferences, Develop practical strategies to recognize and manage adverse events related to the use of PARP inhibitors, particularly with long-term use such as in maintenance settings, in patients with ovarian cancer.

Listen to Prof Nicoletta Colombo and Bradley J. Monk, MD, FACS, FACOG, discuss current best practices for biomarker testing for your patients with advanced ovarian cancer.In this episode, Prof Nicoletta Colombo and Bradley J. Monk, MD, FACS, FACOG, discuss current best practices for biomarker testing in the management of patients with advanced ovarian cancer. Topics include:Subtypes of ovarian cancerBRCA mutation testing Homologous recombination deficiency testing Presenters:Professor Nicoletta ColomboProfessor of Obstetrics and GynecologyUniversity of Milan-BicoccaEuropean Institute of OncologyMilan, ItalyBradley J. Monk MD, FACS, FACOGProfessorDivision of Gynecologic OncologyArizona Oncology (US Oncology Network)University of Arizona College of Medicine--PhoenixCreighton University School of Medicine at St Joseph's HospitalPhoenix, ArizonaContent based on an online CME program supported by an educational grant from GlaxoSmithKline.Link to full program:https://bit.ly/2Scnp2N

In this episode, Isabelle Ray Coquard, MD, PhD and Bradley J. Monk, MD, FACS, FACOG, discuss current first-line maintenance therapy options for patients with advanced ovarian cancer. Presenters:Prof Isabelle Ray CoquardProfessor of Department of Medical OncologyClinical Science Institute of the Léon Bérard CenterLyon, FranceBradley J. Monk MD, FACS, FACOGProfessorDivision of Gynecologic OncologyArizona Oncology (US Oncology Network)University of Arizona College of Medicine--PhoenixCreighton University School of Medicine at St Joseph's HospitalPhoenix, ArizonaContent based on an online CME program supported by an educational grant from GlaxoSmithKline.Link to full program:https://bit.ly/2Scnp2N  

Go online to PeerView.com/QYX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The advent of PARP inhibitors and precise selection of patients using companion diagnostics have improved outcomes for patients with advanced ovarian cancer and provided new opportunities for oncologists to individualize care. In this activity, based on a recent live webcast, a panel of leading experts discuss the rationale behind the use of PARP inhibition in ovarian cancer and how these agents and their companion diagnostics can be used in clinical practice in a variety of settings. Using case vignettes, the experts address real-world applications of the latest research, including how to prevent and manage adverse events associated with the use of PARP inhibitors and determine which patients may benefit from enrollment in clinical trials testing these agents alone or in combination with other treatments. Upon completion of this activity, participants should be better able to: Review the rationale of PARP inhibitors targeting DNA repair pathway mutations as well as their validated clinical evidence in ovarian cancer, Employ PARP inhibitor therapy and their companion diagnostics, when appropriate, for patients with ovarian cancer in frontline maintenance, pretreated platinum-sensitive, pretreated platinum-refractory, and other settings, Plan strategies to prevent and/or manage the PARP inhibitor-associated adverse events, particularly in long-term use (eg, maintenance settings), in patients with ovarian cancer, Identify patients eligible for enrollment into clinical trials testing PARP inhibitors, including as combination approaches, in different treatment settings for ovarian cancer.

Go online to PeerView.com/QYX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The advent of PARP inhibitors and precise selection of patients using companion diagnostics have improved outcomes for patients with advanced ovarian cancer and provided new opportunities for oncologists to individualize care. In this activity, based on a recent live webcast, a panel of leading experts discuss the rationale behind the use of PARP inhibition in ovarian cancer and how these agents and their companion diagnostics can be used in clinical practice in a variety of settings. Using case vignettes, the experts address real-world applications of the latest research, including how to prevent and manage adverse events associated with the use of PARP inhibitors and determine which patients may benefit from enrollment in clinical trials testing these agents alone or in combination with other treatments. Upon completion of this activity, participants should be better able to: Review the rationale of PARP inhibitors targeting DNA repair pathway mutations as well as their validated clinical evidence in ovarian cancer, Employ PARP inhibitor therapy and their companion diagnostics, when appropriate, for patients with ovarian cancer in frontline maintenance, pretreated platinum-sensitive, pretreated platinum-refractory, and other settings, Plan strategies to prevent and/or manage the PARP inhibitor-associated adverse events, particularly in long-term use (eg, maintenance settings), in patients with ovarian cancer, Identify patients eligible for enrollment into clinical trials testing PARP inhibitors, including as combination approaches, in different treatment settings for ovarian cancer.

Go online to PeerView.com/QYX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The advent of PARP inhibitors and precise selection of patients using companion diagnostics have improved outcomes for patients with advanced ovarian cancer and provided new opportunities for oncologists to individualize care. In this activity, based on a recent live webcast, a panel of leading experts discuss the rationale behind the use of PARP inhibition in ovarian cancer and how these agents and their companion diagnostics can be used in clinical practice in a variety of settings. Using case vignettes, the experts address real-world applications of the latest research, including how to prevent and manage adverse events associated with the use of PARP inhibitors and determine which patients may benefit from enrollment in clinical trials testing these agents alone or in combination with other treatments. Upon completion of this activity, participants should be better able to: Review the rationale of PARP inhibitors targeting DNA repair pathway mutations as well as their validated clinical evidence in ovarian cancer, Employ PARP inhibitor therapy and their companion diagnostics, when appropriate, for patients with ovarian cancer in frontline maintenance, pretreated platinum-sensitive, pretreated platinum-refractory, and other settings, Plan strategies to prevent and/or manage the PARP inhibitor-associated adverse events, particularly in long-term use (eg, maintenance settings), in patients with ovarian cancer, Identify patients eligible for enrollment into clinical trials testing PARP inhibitors, including as combination approaches, in different treatment settings for ovarian cancer.

Go online to PeerView.com/QYX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The advent of PARP inhibitors and precise selection of patients using companion diagnostics have improved outcomes for patients with advanced ovarian cancer and provided new opportunities for oncologists to individualize care. In this activity, based on a recent live webcast, a panel of leading experts discuss the rationale behind the use of PARP inhibition in ovarian cancer and how these agents and their companion diagnostics can be used in clinical practice in a variety of settings. Using case vignettes, the experts address real-world applications of the latest research, including how to prevent and manage adverse events associated with the use of PARP inhibitors and determine which patients may benefit from enrollment in clinical trials testing these agents alone or in combination with other treatments. Upon completion of this activity, participants should be better able to: Review the rationale of PARP inhibitors targeting DNA repair pathway mutations as well as their validated clinical evidence in ovarian cancer, Employ PARP inhibitor therapy and their companion diagnostics, when appropriate, for patients with ovarian cancer in frontline maintenance, pretreated platinum-sensitive, pretreated platinum-refractory, and other settings, Plan strategies to prevent and/or manage the PARP inhibitor-associated adverse events, particularly in long-term use (eg, maintenance settings), in patients with ovarian cancer, Identify patients eligible for enrollment into clinical trials testing PARP inhibitors, including as combination approaches, in different treatment settings for ovarian cancer.

Go online to PeerView.com/QYX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The advent of PARP inhibitors and precise selection of patients using companion diagnostics have improved outcomes for patients with advanced ovarian cancer and provided new opportunities for oncologists to individualize care. In this activity, based on a recent live webcast, a panel of leading experts discuss the rationale behind the use of PARP inhibition in ovarian cancer and how these agents and their companion diagnostics can be used in clinical practice in a variety of settings. Using case vignettes, the experts address real-world applications of the latest research, including how to prevent and manage adverse events associated with the use of PARP inhibitors and determine which patients may benefit from enrollment in clinical trials testing these agents alone or in combination with other treatments. Upon completion of this activity, participants should be better able to: Review the rationale of PARP inhibitors targeting DNA repair pathway mutations as well as their validated clinical evidence in ovarian cancer, Employ PARP inhibitor therapy and their companion diagnostics, when appropriate, for patients with ovarian cancer in frontline maintenance, pretreated platinum-sensitive, pretreated platinum-refractory, and other settings, Plan strategies to prevent and/or manage the PARP inhibitor-associated adverse events, particularly in long-term use (eg, maintenance settings), in patients with ovarian cancer, Identify patients eligible for enrollment into clinical trials testing PARP inhibitors, including as combination approaches, in different treatment settings for ovarian cancer.

Go online to PeerView.com/QYX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The advent of PARP inhibitors and precise selection of patients using companion diagnostics have improved outcomes for patients with advanced ovarian cancer and provided new opportunities for oncologists to individualize care. In this activity, based on a recent live webcast, a panel of leading experts discuss the rationale behind the use of PARP inhibition in ovarian cancer and how these agents and their companion diagnostics can be used in clinical practice in a variety of settings. Using case vignettes, the experts address real-world applications of the latest research, including how to prevent and manage adverse events associated with the use of PARP inhibitors and determine which patients may benefit from enrollment in clinical trials testing these agents alone or in combination with other treatments. Upon completion of this activity, participants should be better able to: Review the rationale of PARP inhibitors targeting DNA repair pathway mutations as well as their validated clinical evidence in ovarian cancer, Employ PARP inhibitor therapy and their companion diagnostics, when appropriate, for patients with ovarian cancer in frontline maintenance, pretreated platinum-sensitive, pretreated platinum-refractory, and other settings, Plan strategies to prevent and/or manage the PARP inhibitor-associated adverse events, particularly in long-term use (eg, maintenance settings), in patients with ovarian cancer, Identify patients eligible for enrollment into clinical trials testing PARP inhibitors, including as combination approaches, in different treatment settings for ovarian cancer.

Go online to PeerView.com/VSY860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert oncologist discusses recent developments in the use of PARP inhibitors and their companion diagnostics in advanced ovarian cancer and shares insight on incorporating PARP inhibitors into individualized treatment plans to improve patient outcomes in a variety of ovarian cancer settings. Upon completion of this activity, participants should be better able to: Review the rationale of PARP inhibitors targeting DNA repair pathway mutations, as well as their validated clinical evidence in ovarian cancer, Employ PARP inhibitor therapy and their companion diagnostics, when appropriate, for patients with ovarian cancer in frontline maintenance, pretreated platinum-sensitive, pretreated platinum-refractory, and other settings, Plan strategies to prevent and/or manage the PARP inhibitor-associated adverse events, particularly in long-term use (eg, maintenance settings), in patients with ovarian cancer, Identify patients eligible for enrollment into clinical trials testing PARP inhibitors, including as combination approaches, in different treatment settings for ovarian cancer.

Go online to PeerView.com/VSY860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert oncologist discusses recent developments in the use of PARP inhibitors and their companion diagnostics in advanced ovarian cancer and shares insight on incorporating PARP inhibitors into individualized treatment plans to improve patient outcomes in a variety of ovarian cancer settings. Upon completion of this activity, participants should be better able to: Review the rationale of PARP inhibitors targeting DNA repair pathway mutations, as well as their validated clinical evidence in ovarian cancer, Employ PARP inhibitor therapy and their companion diagnostics, when appropriate, for patients with ovarian cancer in frontline maintenance, pretreated platinum-sensitive, pretreated platinum-refractory, and other settings, Plan strategies to prevent and/or manage the PARP inhibitor-associated adverse events, particularly in long-term use (eg, maintenance settings), in patients with ovarian cancer, Identify patients eligible for enrollment into clinical trials testing PARP inhibitors, including as combination approaches, in different treatment settings for ovarian cancer.

Go online to PeerView.com/VSY860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert oncologist discusses recent developments in the use of PARP inhibitors and their companion diagnostics in advanced ovarian cancer and shares insight on incorporating PARP inhibitors into individualized treatment plans to improve patient outcomes in a variety of ovarian cancer settings. Upon completion of this activity, participants should be better able to: Review the rationale of PARP inhibitors targeting DNA repair pathway mutations, as well as their validated clinical evidence in ovarian cancer, Employ PARP inhibitor therapy and their companion diagnostics, when appropriate, for patients with ovarian cancer in frontline maintenance, pretreated platinum-sensitive, pretreated platinum-refractory, and other settings, Plan strategies to prevent and/or manage the PARP inhibitor-associated adverse events, particularly in long-term use (eg, maintenance settings), in patients with ovarian cancer, Identify patients eligible for enrollment into clinical trials testing PARP inhibitors, including as combination approaches, in different treatment settings for ovarian cancer.

Go online to PeerView.com/VSY860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert oncologist discusses recent developments in the use of PARP inhibitors and their companion diagnostics in advanced ovarian cancer and shares insight on incorporating PARP inhibitors into individualized treatment plans to improve patient outcomes in a variety of ovarian cancer settings. Upon completion of this activity, participants should be better able to: Review the rationale of PARP inhibitors targeting DNA repair pathway mutations, as well as their validated clinical evidence in ovarian cancer, Employ PARP inhibitor therapy and their companion diagnostics, when appropriate, for patients with ovarian cancer in frontline maintenance, pretreated platinum-sensitive, pretreated platinum-refractory, and other settings, Plan strategies to prevent and/or manage the PARP inhibitor-associated adverse events, particularly in long-term use (eg, maintenance settings), in patients with ovarian cancer, Identify patients eligible for enrollment into clinical trials testing PARP inhibitors, including as combination approaches, in different treatment settings for ovarian cancer.

Go online to PeerView.com/VSY860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert oncologist discusses recent developments in the use of PARP inhibitors and their companion diagnostics in advanced ovarian cancer and shares insight on incorporating PARP inhibitors into individualized treatment plans to improve patient outcomes in a variety of ovarian cancer settings. Upon completion of this activity, participants should be better able to: Review the rationale of PARP inhibitors targeting DNA repair pathway mutations, as well as their validated clinical evidence in ovarian cancer, Employ PARP inhibitor therapy and their companion diagnostics, when appropriate, for patients with ovarian cancer in frontline maintenance, pretreated platinum-sensitive, pretreated platinum-refractory, and other settings, Plan strategies to prevent and/or manage the PARP inhibitor-associated adverse events, particularly in long-term use (eg, maintenance settings), in patients with ovarian cancer, Identify patients eligible for enrollment into clinical trials testing PARP inhibitors, including as combination approaches, in different treatment settings for ovarian cancer.

Go online to PeerView.com/VSY860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert oncologist discusses recent developments in the use of PARP inhibitors and their companion diagnostics in advanced ovarian cancer and shares insight on incorporating PARP inhibitors into individualized treatment plans to improve patient outcomes in a variety of ovarian cancer settings. Upon completion of this activity, participants should be better able to: Review the rationale of PARP inhibitors targeting DNA repair pathway mutations, as well as their validated clinical evidence in ovarian cancer, Employ PARP inhibitor therapy and their companion diagnostics, when appropriate, for patients with ovarian cancer in frontline maintenance, pretreated platinum-sensitive, pretreated platinum-refractory, and other settings, Plan strategies to prevent and/or manage the PARP inhibitor-associated adverse events, particularly in long-term use (eg, maintenance settings), in patients with ovarian cancer, Identify patients eligible for enrollment into clinical trials testing PARP inhibitors, including as combination approaches, in different treatment settings for ovarian cancer.

Go online to PeerView.com/XUK860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Exploiting the impact of mutations in DNA damage response (DDR) pathways on tumorigenesis has led to advances in the development of targeted therapies such as poly-ADP ribose polymerase (PARP) inhibitors for patients with relevant cancers. These agents are currently approved for several indications and are under investigation in a number of other tumor types. Increasingly, optimal care for patients with breast, ovarian, pancreatic, and other cancers must include genetic and other biomarker testing to inform risk, prognosis, and treatment selection. This PeerView inExchange features two leading experts who share the fundamentals of DDR pathway biology and their insights into current and emerging biomarkers, genetic testing guidelines, indications, and mechanisms, as well as the latest evidence on PARP inhibitors and other novel therapeutic approaches. The experts also provide guidance on how to incorporate molecular testing into current clinical practice to ensure that patients who have or are at risk for DDR-mutant cancers receive optimal care. Upon completion of this activity, participants should be better able to: Discuss key features of the DNA damage response (DDR) pathway and the rationale for therapeutic targeting of DDR mutations in patients with cancer, Compare current and emerging actionable mutations associated with DDR (eg, BRCA1/2) and the different testing methods used to identify these biomarkers, Evaluate recent clinical evidence on current and emerging agents and combinations targeting DNA repair mechanisms, including poly-ADP ribose polymerase (PARP) inhibitors, Describe the guidelines for genetic risk evaluation, genetic testing procedures, and pre- and post-test counseling for patients who may be at risk for a germline mutation in the DDR pathway, Apply guideline-based recommendations to identify patients who should receive genetic testing, provide effective genetic counseling, and tailor biomarker testing options to the individual patient's needs.

Go online to PeerView.com/XUK860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Exploiting the impact of mutations in DNA damage response (DDR) pathways on tumorigenesis has led to advances in the development of targeted therapies such as poly-ADP ribose polymerase (PARP) inhibitors for patients with relevant cancers. These agents are currently approved for several indications and are under investigation in a number of other tumor types. Increasingly, optimal care for patients with breast, ovarian, pancreatic, and other cancers must include genetic and other biomarker testing to inform risk, prognosis, and treatment selection. This PeerView inExchange features two leading experts who share the fundamentals of DDR pathway biology and their insights into current and emerging biomarkers, genetic testing guidelines, indications, and mechanisms, as well as the latest evidence on PARP inhibitors and other novel therapeutic approaches. The experts also provide guidance on how to incorporate molecular testing into current clinical practice to ensure that patients who have or are at risk for DDR-mutant cancers receive optimal care. Upon completion of this activity, participants should be better able to: Discuss key features of the DNA damage response (DDR) pathway and the rationale for therapeutic targeting of DDR mutations in patients with cancer, Compare current and emerging actionable mutations associated with DDR (eg, BRCA1/2) and the different testing methods used to identify these biomarkers, Evaluate recent clinical evidence on current and emerging agents and combinations targeting DNA repair mechanisms, including poly-ADP ribose polymerase (PARP) inhibitors, Describe the guidelines for genetic risk evaluation, genetic testing procedures, and pre- and post-test counseling for patients who may be at risk for a germline mutation in the DDR pathway, Apply guideline-based recommendations to identify patients who should receive genetic testing, provide effective genetic counseling, and tailor biomarker testing options to the individual patient's needs.

Go online to PeerView.com/XUK860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Exploiting the impact of mutations in DNA damage response (DDR) pathways on tumorigenesis has led to advances in the development of targeted therapies such as poly-ADP ribose polymerase (PARP) inhibitors for patients with relevant cancers. These agents are currently approved for several indications and are under investigation in a number of other tumor types. Increasingly, optimal care for patients with breast, ovarian, pancreatic, and other cancers must include genetic and other biomarker testing to inform risk, prognosis, and treatment selection. This PeerView inExchange features two leading experts who share the fundamentals of DDR pathway biology and their insights into current and emerging biomarkers, genetic testing guidelines, indications, and mechanisms, as well as the latest evidence on PARP inhibitors and other novel therapeutic approaches. The experts also provide guidance on how to incorporate molecular testing into current clinical practice to ensure that patients who have or are at risk for DDR-mutant cancers receive optimal care. Upon completion of this activity, participants should be better able to: Discuss key features of the DNA damage response (DDR) pathway and the rationale for therapeutic targeting of DDR mutations in patients with cancer, Compare current and emerging actionable mutations associated with DDR (eg, BRCA1/2) and the different testing methods used to identify these biomarkers, Evaluate recent clinical evidence on current and emerging agents and combinations targeting DNA repair mechanisms, including poly-ADP ribose polymerase (PARP) inhibitors, Describe the guidelines for genetic risk evaluation, genetic testing procedures, and pre- and post-test counseling for patients who may be at risk for a germline mutation in the DDR pathway, Apply guideline-based recommendations to identify patients who should receive genetic testing, provide effective genetic counseling, and tailor biomarker testing options to the individual patient's needs.

Go online to PeerView.com/XUK860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Exploiting the impact of mutations in DNA damage response (DDR) pathways on tumorigenesis has led to advances in the development of targeted therapies such as poly-ADP ribose polymerase (PARP) inhibitors for patients with relevant cancers. These agents are currently approved for several indications and are under investigation in a number of other tumor types. Increasingly, optimal care for patients with breast, ovarian, pancreatic, and other cancers must include genetic and other biomarker testing to inform risk, prognosis, and treatment selection. This PeerView inExchange features two leading experts who share the fundamentals of DDR pathway biology and their insights into current and emerging biomarkers, genetic testing guidelines, indications, and mechanisms, as well as the latest evidence on PARP inhibitors and other novel therapeutic approaches. The experts also provide guidance on how to incorporate molecular testing into current clinical practice to ensure that patients who have or are at risk for DDR-mutant cancers receive optimal care. Upon completion of this activity, participants should be better able to: Discuss key features of the DNA damage response (DDR) pathway and the rationale for therapeutic targeting of DDR mutations in patients with cancer, Compare current and emerging actionable mutations associated with DDR (eg, BRCA1/2) and the different testing methods used to identify these biomarkers, Evaluate recent clinical evidence on current and emerging agents and combinations targeting DNA repair mechanisms, including poly-ADP ribose polymerase (PARP) inhibitors, Describe the guidelines for genetic risk evaluation, genetic testing procedures, and pre- and post-test counseling for patients who may be at risk for a germline mutation in the DDR pathway, Apply guideline-based recommendations to identify patients who should receive genetic testing, provide effective genetic counseling, and tailor biomarker testing options to the individual patient's needs.

Go online to PeerView.com/XUK860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Exploiting the impact of mutations in DNA damage response (DDR) pathways on tumorigenesis has led to advances in the development of targeted therapies such as poly-ADP ribose polymerase (PARP) inhibitors for patients with relevant cancers. These agents are currently approved for several indications and are under investigation in a number of other tumor types. Increasingly, optimal care for patients with breast, ovarian, pancreatic, and other cancers must include genetic and other biomarker testing to inform risk, prognosis, and treatment selection. This PeerView inExchange features two leading experts who share the fundamentals of DDR pathway biology and their insights into current and emerging biomarkers, genetic testing guidelines, indications, and mechanisms, as well as the latest evidence on PARP inhibitors and other novel therapeutic approaches. The experts also provide guidance on how to incorporate molecular testing into current clinical practice to ensure that patients who have or are at risk for DDR-mutant cancers receive optimal care. Upon completion of this activity, participants should be better able to: Discuss key features of the DNA damage response (DDR) pathway and the rationale for therapeutic targeting of DDR mutations in patients with cancer, Compare current and emerging actionable mutations associated with DDR (eg, BRCA1/2) and the different testing methods used to identify these biomarkers, Evaluate recent clinical evidence on current and emerging agents and combinations targeting DNA repair mechanisms, including poly-ADP ribose polymerase (PARP) inhibitors, Describe the guidelines for genetic risk evaluation, genetic testing procedures, and pre- and post-test counseling for patients who may be at risk for a germline mutation in the DDR pathway, Apply guideline-based recommendations to identify patients who should receive genetic testing, provide effective genetic counseling, and tailor biomarker testing options to the individual patient's needs.

Go online to PeerView.com/XUK860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Exploiting the impact of mutations in DNA damage response (DDR) pathways on tumorigenesis has led to advances in the development of targeted therapies such as poly-ADP ribose polymerase (PARP) inhibitors for patients with relevant cancers. These agents are currently approved for several indications and are under investigation in a number of other tumor types. Increasingly, optimal care for patients with breast, ovarian, pancreatic, and other cancers must include genetic and other biomarker testing to inform risk, prognosis, and treatment selection. This PeerView inExchange features two leading experts who share the fundamentals of DDR pathway biology and their insights into current and emerging biomarkers, genetic testing guidelines, indications, and mechanisms, as well as the latest evidence on PARP inhibitors and other novel therapeutic approaches. The experts also provide guidance on how to incorporate molecular testing into current clinical practice to ensure that patients who have or are at risk for DDR-mutant cancers receive optimal care. Upon completion of this activity, participants should be better able to: Discuss key features of the DNA damage response (DDR) pathway and the rationale for therapeutic targeting of DDR mutations in patients with cancer, Compare current and emerging actionable mutations associated with DDR (eg, BRCA1/2) and the different testing methods used to identify these biomarkers, Evaluate recent clinical evidence on current and emerging agents and combinations targeting DNA repair mechanisms, including poly-ADP ribose polymerase (PARP) inhibitors, Describe the guidelines for genetic risk evaluation, genetic testing procedures, and pre- and post-test counseling for patients who may be at risk for a germline mutation in the DDR pathway, Apply guideline-based recommendations to identify patients who should receive genetic testing, provide effective genetic counseling, and tailor biomarker testing options to the individual patient's needs.

Go online to PeerView.com/BBX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, experts in oncology discuss current evidence and clinical insights on the evolving role of poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP) inhibitors in the frontline and recurrent maintenance settings in patients with ovarian cancer. Upon completion of this activity, participants should be better able to: Review the benefits of maintenance therapy on overall patient outcomes in ovarian cancer management, Summarize new evidence on and recent indications for PARP inhibitors as maintenance therapy in the frontline and recurrent advanced ovarian cancer settings, Select appropriate maintenance interventions based on patient and disease characteristics and response to prior therapy in patients with advanced ovarian cancer.

Go online to PeerView.com/BBX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, experts in oncology discuss current evidence and clinical insights on the evolving role of poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP) inhibitors in the frontline and recurrent maintenance settings in patients with ovarian cancer. Upon completion of this activity, participants should be better able to: Review the benefits of maintenance therapy on overall patient outcomes in ovarian cancer management, Summarize new evidence on and recent indications for PARP inhibitors as maintenance therapy in the frontline and recurrent advanced ovarian cancer settings, Select appropriate maintenance interventions based on patient and disease characteristics and response to prior therapy in patients with advanced ovarian cancer.

Go online to PeerView.com/BBX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, experts in oncology discuss current evidence and clinical insights on the evolving role of poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP) inhibitors in the frontline and recurrent maintenance settings in patients with ovarian cancer. Upon completion of this activity, participants should be better able to: Review the benefits of maintenance therapy on overall patient outcomes in ovarian cancer management, Summarize new evidence on and recent indications for PARP inhibitors as maintenance therapy in the frontline and recurrent advanced ovarian cancer settings, Select appropriate maintenance interventions based on patient and disease characteristics and response to prior therapy in patients with advanced ovarian cancer.

Go online to PeerView.com/BBX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, experts in oncology discuss current evidence and clinical insights on the evolving role of poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP) inhibitors in the frontline and recurrent maintenance settings in patients with ovarian cancer. Upon completion of this activity, participants should be better able to: Review the benefits of maintenance therapy on overall patient outcomes in ovarian cancer management, Summarize new evidence on and recent indications for PARP inhibitors as maintenance therapy in the frontline and recurrent advanced ovarian cancer settings, Select appropriate maintenance interventions based on patient and disease characteristics and response to prior therapy in patients with advanced ovarian cancer.

Go online to PeerView.com/BBX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, experts in oncology discuss current evidence and clinical insights on the evolving role of poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP) inhibitors in the frontline and recurrent maintenance settings in patients with ovarian cancer. Upon completion of this activity, participants should be better able to: Review the benefits of maintenance therapy on overall patient outcomes in ovarian cancer management, Summarize new evidence on and recent indications for PARP inhibitors as maintenance therapy in the frontline and recurrent advanced ovarian cancer settings, Select appropriate maintenance interventions based on patient and disease characteristics and response to prior therapy in patients with advanced ovarian cancer.

Go online to PeerView.com/BBX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, experts in oncology discuss current evidence and clinical insights on the evolving role of poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP) inhibitors in the frontline and recurrent maintenance settings in patients with ovarian cancer. Upon completion of this activity, participants should be better able to: Review the benefits of maintenance therapy on overall patient outcomes in ovarian cancer management, Summarize new evidence on and recent indications for PARP inhibitors as maintenance therapy in the frontline and recurrent advanced ovarian cancer settings, Select appropriate maintenance interventions based on patient and disease characteristics and response to prior therapy in patients with advanced ovarian cancer.

Go online to PeerView.com/BBX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, experts in oncology discuss current evidence and clinical insights on the evolving role of poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP) inhibitors in the frontline and recurrent maintenance settings in patients with ovarian cancer. Upon completion of this activity, participants should be better able to: Review the benefits of maintenance therapy on overall patient outcomes in ovarian cancer management, Summarize new evidence on and recent indications for PARP inhibitors as maintenance therapy in the frontline and recurrent advanced ovarian cancer settings, Select appropriate maintenance interventions based on patient and disease characteristics and response to prior therapy in patients with advanced ovarian cancer.

Go online to PeerView.com/BBX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, experts in oncology discuss current evidence and clinical insights on the evolving role of poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP) inhibitors in the frontline and recurrent maintenance settings in patients with ovarian cancer. Upon completion of this activity, participants should be better able to: Review the benefits of maintenance therapy on overall patient outcomes in ovarian cancer management, Summarize new evidence on and recent indications for PARP inhibitors as maintenance therapy in the frontline and recurrent advanced ovarian cancer settings, Select appropriate maintenance interventions based on patient and disease characteristics and response to prior therapy in patients with advanced ovarian cancer.

30 de setembro de 2019 Cobertura de congressos ESMO 2019: Dr. Bradley J. Monk – Destaques em câncer de ovário do Presidential Symposium Dr. Bradley J. Monk comenta três estudos em câncer de ovário apresentados no Presidential Symposium da ESMO 2019: terapia com niraparibe em pacientes com câncer de ovário avançado recentemente diagnosticadas (PRIMA/ENGOT-OV26/GOG-3012 study), o estudo de fase III PAOLA-1/ENGOT-ov25 com olaparibe + bevacizumabe como terapia de manutenção em pacientes com câncer de ovário avançado recentemente diagnosticadas, tratadas com quimioterapia à base de platina + bevacizumabe, e o estudo VELIA/GOG-3005 com a integração de veliparibe à quimioterapia e manutenção em mulheres com carcinoma seroso de alto grau de origem ovariana, trompa de Falópio ou origem peritoneal primária.

Host: Bradley J. Monk, MD, FACS, FACOG There are limited treatment options in the first-line setting for patients with advanced ovarian cancer. Many patients experience disease recurrence or progression with first-line chemotherapy, with approximately 10% to 30% experiencing long-term survival. Anti-angiogenesis agents, such as bevacizumab and nintedanib, have been investigated in clinical trials for the first-line treatment of patients with advanced ovarian cancer. Bevacizumab is now FDA approved in combination with carboplatin and paclitaxel, followed by bevacizumab as a single agent, for the treatment of women with stage III or stage IV epithelial ovarian, fallopian tube, or primary peritoneal cancer following initial surgical resection. AXIS routinely collects and analyzes data gathered from participants in our live grand rounds programs. These questions provide incredible insight regarding the persistent challenges that clinicians face when trying to optimize treatment planning to verify where clinical practice gaps exist. This activity will provide expert answers to questions asked during a recent grand rounds series on anti-angiogenesis agents for the first-line treatment of advanced ovarian cancer.

BRADLEY J. MONK, M.D., F.A.C.O.G., F.A.C.S. Division of Gynecologic Oncology Department of Obstetrics and Gynecology Comprehensive Cancer Center Creighton University School of Medicine at St. Joseph’s Hospital and Medical Center, a member of Catholic Healthcare West Phoenix, AZ 85013

BRADLEY J. MONK, M.D., F.A.C.O.G., F.A.C.S. Professor Division of Gynecologic Oncology Department of Obstetrics and Gynecology Comprehensive Cancer Center Creighton University School of Medicine at St. Joseph’s Hospital and Medical Center, a member of Catholic Healthcare West Phoenix, AZ

Presented by Bradley J. Monk, MD