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In this episode, Dr Tsen Vei Lim talks to Zachary Bryant, a PhD candidate at the Matilda Centre for Research in Mental Health and Substance Use, University of Sydney, Australia. The interview covers Zachary's research report on the relationship between MDMA (or ecstasy) use in youth adulthood and anxiety or depressive disorders in later adult life. The effects of MDMA [1:20]The prevalence of MDMA use and reasons why people take it [02:00]The relevance of MDMA for depression and anxiety [03:05]The use of the Victorian Adolescent Health Cohort Study to answer Zachary's research question [04:17]The key findings of the study [06:50]Some reasons to explain the relationship found between MDMA use and anxiety but not depression [07:43]The self-medication hypothesis [10:04]The implication of the findings for clinical practice [11:02]The importance of replicating the findings in different cohorts and with more recent data [14:03] About Tsen Vei Lim: Tsen Vei is an academic fellow supported by the Society for the Study of Addiction, currently based at the Department of Psychiatry at the University of Cambridge. His research integrates computational modelling, experimental psychology, and neuroimaging to understand the neuropsychological basis of addictive behaviours. He holds a PhD in Psychiatry from the University of Cambridge (UK) and a BSc in Psychology from the University of Bath (UK). About Zachary Bryant: Zachary is a PhD candidate and research officer at the University of Sydney's Matilda Centre for Research in Mental Health and Substance Use. His doctoral research examines the relationship between MDMA (ecstasy) use and mood, with a focus on implications for therapeutic applications. More broadly, his work explores the epidemiology of psychedelic use and applies advanced causal approaches to substance use research. He is particularly interested in emerging data collection and analysis methods, including intensive longitudinal designs such as Ecological Momentary Assessment (EMA).The authors have no conflicts of interest to disclose. Original article: The relationship between 3,4-methylenedioxymethamphetamine (MDMA) use in young adulthood and anxiety or depressive disorders in the mid-30s: Findings from the Victorian Adolescent Health Cohort Study - https://doi.org/10.1111/add.70173The opinions expressed in this podcast reflect the views of the host and interviewees and do not necessarily represent the opinions or official positions of the SSA or Addiction journal.The SSA does not endorse or guarantee the accuracy of the information in external sources or links and accepts no responsibility or liability for any consequences arising from the use of such information. Hosted on Acast. See acast.com/privacy for more information.
This week I discuss the latest BBC study on AI answer quality from public data sources. As I discuss, the BBC and EBU found that 45% of news queries produce erroneous answers, so the reality has set in: public domain AI engines are neither “superintelligent” nor are they perfect. Yet they are very self-confident. So we, as users, need to be careful. As you'll hear, there are three things to consider here, and you can read more about this in my latest article on the topic. For those of us in corporate roles, the message is clear: data quality must be our #1 priority, and this is a whole new domain for HR and other service functions. Like this podcast? Rate us on Spotify or Apple or YouTube. Additional Information BBC Research Findings Interpretation of the Findings and the “polluted corpus” problem Claude's admission of the “polluted corpus” problem AI Thinking Skills You Need To Stay Safe (podcast) Galileo: The World's Trusted Agent for Everything HR Chapters (00:00:00) - The Lack of Trust in AI Agents(00:12:18) - Human Decision-Making in an AI World(00:16:09) - Third area of business re-engineering AI systems(00:20:19) - Crucial Data Source: Galileo for HR Data
IrishJobs has today published new data from its Hiring Trends Update, revealing that nearly 1 in 4 employers expect to increase hiring in 2026. The IrishJobs Hiring Trends Update is a new biannual research report on the state of the recruitment market in Ireland. The research gathered insights from 500 employers and 1,000 professionals in Ireland on the evolving hiring landscape and shifting attitudes and actions across the market. The research also includes data from OTT, an in-house tool developed by the Stepstone Group, the parent company of IrishJobs, which analyses online data on job postings and associated information. In-demand skills As employers continue to navigate a highly competitive market for demand, sourcing candidates with in-demand skills is a top challenge. Nearly 7 in 10 employers (69%) report struggling to recruit talent with the right skills. Technical skills, such as programming, data analysis and AI competencies, are the most highly sought-after skills by employers. 30% of employers are prioritising the recruitment of talent with technical skills. 28% of employers are looking to hire candidates with soft skills such as problem-solving, collaboration, and communication. 25% of employers say that recruiting candidates with leadership and people management skills is a top priority. Pace of hiring The tight talent landscape is impacting the length of time to successful hiring. The median time for successful hiring is 10 weeks, as employers continue to face challenges in sourcing the right candidates for key positions. Findings show that recruiters are increasingly using AI tools and automation to reduce administrative burdens and streamline the hiring process. Nearly half of employers (47%) surveyed are using AI to draft job adverts. 35% of employers are using AI tools to help schedule interviews with job candidates. Hiring landscape There is a positive hiring outlook for 2026, with nearly 1 in 4 employers (24%) in Ireland planning on increasing recruitment over the next six months, indicating growing confidence among employers following a period of heightened geopolitical and trade volatility. Large enterprises have the most positive outlook on future hiring, with 27% of these firms expected to increase recruitment over the coming months. Findings show that smaller firms are more cautious on potential growth, with 21% of SMEs forecasting an increase in hiring in 2026. 21% of employers plan on increasing spending on hiring for more specialist roles, while 19% expect to increase hiring for temporary roles and contractors. 33% of employers surveyed have increased their levels of recruitment since April 2025, according to the report findings. Large businesses were the most active in recruitment, with 35% of these firms hiring more staff over this period. Findings show that 31% of SMEs have increased hiring since April 2025. However, there are also signs of cooling in certain areas of the labour market. 24% of employers reported restructuring certain teams or departments within their organisation over the previous six months. Increased jobseeker activity ahead Despite elevated uncertainty, jobseeker activity has remained robust across the labour market, with 21% of candidates actively looking for a new job in September 2025. However, there are signs that greater stability may lead to increased activity in the months ahead. Findings show that 29% of candidates plan to look for a new job in 2026. Salary is the top factor candidates consider when evaluating a new job and employer. Work-life balance is the second most important factor, with 31% of candidates considering it important when considering a new job. There are also signs that international volatility is having a growing impact on the selection of employers by candidates, with 29% of candidates ranking job security as a crucial factor influencing selection. Flexibility is increasingly a baseline expectation for many job candidates. 71% of candidates woul...
#viral #viralvideo #instagrampodcast #media #productionstudio #storytelling #storytime #growthmindset #production #producer #writersroom #radiohost #goddid #blessed #opportunity #partnership #spotify #IHeartMedia #IHeartRadio #Radio #RadioShow#OnAirNow#LiveOnAir#RadioVibes#PodcastAndChill#BroadcastLife#TuneInNow#SoundWaves#RadioCulture#DigitalRadio#MicCheck#BehindTheMic#RadioPersonality#VoiceOfThePeople#KLPEntertainment© 2025 K.L.P Entertainment Filmworks© 2025 K.L.P Studios
In this episode we chat with Professor Bronwyn Hemsley and Dr Lucy Bryant, both of the University of Technology Sydney, about their recent systematic review of interventions based on Gestalt Language Processing and Natural Language Acquisition. The discussion covers:What was the clinical question you were trying to answer?How did you go about undertaking the review? What were the key findings?What does this mean for the speech and language therapy profession?With thanks to panellists:Professor Bronwyn Hemsley, Head of Speech Pathology at The University of Technology Sydney and co-lead of the UTS Disability Research NetworkDr Lucy Bryant, Senior Lecturer in Speech Pathology, The University of Technology, SydneyResources:Bryant, L., Bowen, C., Grove, R. et al. Systematic Review of Interventions Based on Gestalt Language Processing and Natural Language Acquisition (GLP/NLA): Clinical Implications of Absence of Evidence and Cautions for Clinicians and Parents. Curr Dev Disord Rep 12, 2 (2024). https://doi.org/10.1007/s40474-024-00312-zhttps://link.springer.com/article/10.1007/s40474-024-00312-z To read about the prevalence of echolalia mentioned in this podcast see the open access review: Sutherland, R., Bryant, L., Dray, J. & Robert's, J. (2024). Prevalence of Echolalia in Autism: A Rapid Review of Current Findings and a Journey Back to Historical Data. Current Developmental Disorders Reports, 11, 171–183 (2024). https://doi.org/10.1007/s40474-024-00311-0https://link.springer.com/article/10.1007/s40474-024-00311-0Please be aware that the views expressed are those of the guests and not the RCSLT.Please do take a few moments to respond to our podcast survey: uk.surveymonkey.com/r/LG5HC3R
#viral #viralvideo #instagrampodcast #media #productionstudio #storytelling #storytime #growthmindset #production #producer #writersroom #radiohost #goddid #blessed #opportunity #partnership #spotify #IHeartMedia #IHeartRadio #Radio #RadioShow#OnAirNow#LiveOnAir#RadioVibes#PodcastAndChill#BroadcastLife#TuneInNow#SoundWaves#RadioCulture#DigitalRadio#MicCheck#BehindTheMic#RadioPersonality#VoiceOfThePeople#KLPEntertainment© 2025 K.L.P Entertainment Filmworks© 2025 K.L.P Studios
RFK Jr.'s autism claims aren't about helping anyone—they're about deciding who gets to exist in America.
GOP Voters Found More Moderate on Fiscal Issues and Driven by Cultural Anti-Progressivism, According to New Analysis Ryan Streeter with John Batchelor Ryan Streeter discussed findings showing Republican voters are more moderate than portrayed, especially on entitlement cuts. They prioritize a healthy economy and law and order. Isolationism is not prominent, though they oppose excessive foreign spending. MAGA Republicanism is defined primarily by cultural issues, like anti-progressivism and concern over immigration, often outweighing economic policies like tariffs. Streeter concludes that rank and file voters are not as radical as national politics suggest.
GOP Voters Found More Moderate on Fiscal Issues and Driven by Cultural Anti-Progressivism, According to New Analysis Ryan Streeter with John Batchelor Ryan Streeter discussed findings showing Republican voters are more moderate than portrayed, especially on entitlement cuts. They prioritize a healthy economy and law and order. Isolationism is not prominent, though they oppose excessive foreign spending. MAGA Republicanism is defined primarily by cultural issues, like anti-progressivism and concern over immigration, often outweighing economic policies like tariffs. Streeter concludes that rank and file voters are not as radical as national politics suggest.
Discover how AI is revolutionizing the world of security in this episode of GRC Chats! We discussed the "210% rise in vulnerability findings" uncovered in the latest Hacker Powered Security Report with Laurie Mercer, Senior Director of Solutions at HackerOne. Laurie shares exclusive insights into the dramatic growth of AI-powered systems, the evolving landscape of vulnerabilities, and the rise of AI-enabled hack bots. Learn how organizations can adapt to this rapidly changing environment to stay ahead in Risk Management, Cyber Security, and ethical hacking.
We loved recording this episode! The main topic was the article that rocked the athletic world last week, which asserted that many protein powders had unsafe amounts of lead contamination. We broke down the numbers to reach a much more nuanced conclusion that should help you feel better about it all. And that led to a broader discussion on the perils of advocacy being presented as science. We also talked about a shocking study on 45 asymptomatic people, which found labrum defects in 69% of hips! MRIs are complicated, unveiling mysteries of the human body and the strange line between structural and inflammatory issues. We discuss what it all means!And this one was full of great topics! Other topics: recovery cake, Megan's beastly bike workout, our attempt to program AI with 22 sexy concepts in athletics, a study on actual v. planned carb intake in races, Courtney Dauwalter doing another marathon, a hypothetical about Cole Hocker in ultras, breaking up moderate running with sub-threshold intervals, how grief impacts training, energy deficits in multi-day events, preparing for heat, period parties, and when to FAFO.We love you all! HUZZAH!Prepare for some shockingly high-grade fish,-David and MeganClick "Claim Your Sponsorship" for $40 free credit at The Feed here: thefeed.com/swapGet First Endurance Multi-V: https://thefeed.com/products/first-endurance-multiv-90ct Buy Janji's amazing gear: https://janji.com/ (code "SWAP")For training plans, weekly bonus podcasts, articles, and videos: patreon.com/swap
TWiP solves the case about the female who traveled to Brazil and upon returning home felt movements under her scalp on the back of her head, and present another case for your solving, a man with abnormal brain MRI. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Guest: Eyal Leshem Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Life cycle of Dermatobia hominis (CDC) Letters read on TWiP 267 New Case Man in his 40s, married with 2 children, on Eliquis for a prior DVT, diet-controlled diabetes, who is admitted for evaluation of an abnormal brain MRI. He left AMA but then developed vomiting and returned. CT- Large peripherally enhancing mass lesion in the deep left cerebral hemisphere is associated with considerable vasogenic edema/infiltrative nonenhancing tumor. Mass effect results in left-to-right subfalcine herniation and entrapment of the right lateral ventricle. Findings are typical for glioblastoma. Intracranial abscess tumefactive multiple sclerosis and brain metastasis may mimic this appearance. Recommend supplemental imaging evaluation including gadolinium-enhanced MR brain. MRI- Dominant heterogeneously enhancing mass in the left basal ganglia/peri-insular region measuring 3.1 cm AP by 2.8 cm TR by 2.9 cm cc, with surrounding vasogenic edema resulting in mass effect and midline shift, as detailed above, concerning for high grade glial neoplasm versus metastasis. Additional leptomeningeal nodule in the right postcentral sulcus. Additional smaller peripherally enhancing lesion in the right lateral temporal region with suggestion of leptomeningeal component and measures approximately 0.8 x 0.8 cm, with mild surrounding vasogenic edema. They do a biopsy and pathology comes back as: – Brain tissue with extensive necrosis acute chronic inflammation, and rare microorganisms (on permanent section) -Brain, designated “left brain lesion”, excision: – Brain tissue with extensive necrosis acute and chronic inflammation, reactive gliosis and occasional microorganisms Become a patron of TWiP Send your questions and comments to twip@microbe.tv
The Institute of Internal Auditors Presents: All Things Internal Audit In this episode, Dillon Caldwell and Eric Wilson uncover the psychology behind internal auditing: trust, emotion, bias, credibility, and even burnout. If you've ever wondered why some audits succeed and others stall, this conversation reveals the human side that makes all the difference. HOST: Dillon Caldwell, PhD Manager of Research & Insights, The IIA GUEST: Eric Wilson, CIA Director of Internal Audit & Chief Audit Executive, Gulfport Energy Corporation KEY POINTS: Introduction [00:00–00:00:26] The Human Side of Internal Auditing [00:00:26–00:02:40] Internal Auditing as an Interpersonal Profession [00:03:08–00:04:44] Emotion and Perception in Auditing [00:04:53–00:06:12] Building Credibility and Managing Defensiveness [00:06:25–00:08:29] Reframing Findings as Opportunities [00:10:11–00:13:34] Balancing Independence with Connection [00:16:48–00:19:41] The Culture Factor [00:21:02–00:21:35] Navigating Identity and Expertise [00:21:38–00:24:42] Challenging Institutional Thinking [00:25:04–00:26:42] Psychological Strain and Burnout in Auditing [00:26:47–00:30:12] Closing Thoughts [00:30:20–00:31:10] THE IIA RELATED CONTENT: Interested in this topic? Visit the links below for more resources: 2025 Financial Services Exchange Conference Internal Auditor Magazine: “Playing the Long Game” (Eric Wilson's article) Viewpoints: Human Factors Internal Auditor: "From Critic to Collaborator" Webinar: Internal Auditing and Human Personality: Compatibility Mapping Building a Better Auditor: Human-centric Auditing Vision 2035 Visit The IIA's website or YouTube channel for related topics and more. Follow All Things Internal Audit: Apple PodcastsSpotify LibsynDeezer
ANC's Financial and Moral Decline Deepens Amid Insolvency Threat and Damaging Commission Findings by Radio Islam
The One in Four charity, which supports survivors of child sex abuse, saw more men than women come forward last year, for the first time in its more than 20-year history. Speaking to Shane this morning was CEO of One in Four Deirdre Kenny.
①New archaeological findings reveal colorful bronze ware dating 3,000 years ②Guangzhou subway accepts international contactless bank cards ③Chinese university unveils new AI model for agriculture ④China-Laos Railway handles over 60 million passenger trips ⑤New direct flight route links Chinese tourist city of Zhangjiajie with Singapore ⑥East China's famous Baotu Spring sees water level hit nearly 60-year high
The One in Four charity, which supports survivors of child sex abuse, saw more men than women come forward last year, for the first time in its more than 20-year history. Speaking to Shane this morning was CEO of One in Four Deirdre Kenny.
n the News.. COVID-19 & T1D, Ozempic Pill Progress, Faster Insulin, “Beyond Misconceptions,” and More It's In the News.. a look at the top headlines and stories in the diabetes community. This week's top stories: A new study looks at the link between COVID-19 and very young children, Lilly moves ahead with their Ozempic oral pill, ultra-rapid insulin clears another hurdle, Beyond Type 1 launches a new campaign and more! Find out more about Moms' Night Out Please visit our Sponsors & Partners - they help make the show possible! Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com) Omnipod - Simplify Life Learn about Dexcom Check out VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Twitter Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com Reach out with questions or comments: info@diabetes-connections.com Episode transcription with links: Hello and welcome to Diabetes Connections In the News! I'm Stacey Simms and every other Friday I bring you a short episode with the top diabetes stories and headlines happening now. XX https://www.scientificamerican.com/article/advances-in-type-1-diabetes-science-and-tech/ This article is part of “Innovations In: Type 1 Diabetes,” an editorially independent special report that was produced with financial support from Vertex. XX More evidence linking COVID 19 to type 1 diabetes.. but still exactly why is a mystery. During the COVID-19 pandemic, there was an unexpected increase in the number of cases of type 1 diabetes in Sweden, particularly among children under 5 and young adult men. The infection accelerated the onset of diabetes among children between the ages of 5 and 9. The researchers looked at data from a 17-year period on the incidence of type 1 diabetes among all people under the age of 30 in Sweden. In addition, they compared the risk of developing diabetes among 720,000 individuals with positive COVID-19 tests against a control group of 3.5 million people. The findings are published in the journal Diabetologia. The number of diabetes cases increased by 12% in 2021 and 9% in 2022 compared with previous years. In 2023, the number of cases was back to a normal level. Despite this, the researchers cannot distinguish a clear connection between COVID-19 infection and diabetes, except for children between 5 and 9 years old. They had an increased risk of type 1 diabetes about one month after a COVID-19 infection even though their total risk did not increase. "However, it's clear that the COVID-19 vaccine can be ruled out as a cause of the increase in diabetes cases. The recommendation for the age group where we saw the strongest increase was not to get vaccinated. In addition, other studies on adults have shown that vaccination reduces the risk of developing type 1 diabetes after a COVID infection." https://medicalxpress.com/news/2025-10-diabetes-young-people-pandemic.html XX A new gene therapy approach aimed at protecting people with type 1 diabetes from developing diabetic kidney disease—a serious and common complication of the condition, has shown promising results in a University of Bristol study. Findings from this new study, published in Molecular Therapy, demonstrated a 64% reduction in a damage indicator for kidney disease, paving the way for a potential new treatment. The study, explored the potential of delivering a protein called VEGF-C directly into kidney cells. Previous studies have shown VEGFC could protect against kidney disease as it helps keep blood vessels in the kidney filter healthy, repairing early signs of diabetes-related kidney damage. https://medicalxpress.com/news/2025-10-gene-therapy-kidney-disease-diabetes.html XX The FDA has agreed to consider Afrezza inhaled insulin for children and teens. The company said in August that it submitted a supplemental Biologics License Application (sBLA) for Afrezza in the pediatric population and it's been assigned a decision deadline date of the end of May, 2026. Afrezza first recieved FDA approval for adults (age 18 and up) in June 2014 https://www.drugdeliverybusiness.com/fda-accepts-application-mannkind-inhaled-insulin-kids/ Update on inhaled insulin for kids.. in the open-label, randomized, phase 3 INHALE-1 clinical trial Afrezza demonstrated safe and effective replacement for rapid-acting meal insulin in children with type 1 diabetes (T1D and demonstrates comparable glycemic control to injected rapid-acting insulin. The INHALE-1 clinical trial assessed the safety and efficacy of Afrezza among children and adolescents with T1D, including a total of 230 patients aged 4 to 17 years. Researchers used basal injected insulin and randomly assigned inhaled insulin or rapid-acting analogue for meals, evaluating the change in hemoglobin A1c levels at 26 weeks. After completing 26 weeks of randomly assigned treatment with either Afrezza or rapid-acting insulin injections combined with basal insulin, participants continued receiving the inhaled insulin until week 52 for an extension phase to evaluate the safety and effectiveness of Afrezza with continued use.1,2 https://www.pharmacytimes.com/view/inhaled-insulin-demonstrates-comparable-safety-lung-function-and-efficacy-to-injectable-insulin-in-type-1-diabetes XX Eli Lilly released the results of two new Phase 3 trials of an experimental GLP-1 pill that the company says could become a “foundational treatment” for type 2 diabetes. The Indianapolis-based drugmaker plans to submit global regulatory applications for orforglipron in the treatment of type 2 diabetes next year. The company said it will seek approval of the drug as an obesity medication by the end of 2025. Lilly is trying to build on the success of its Mounjaro/Zepbound franchise by offering patients a pill instead of an injection. But the company is trailing behind rival Novo Nordisk in developing an oral alternative, and data released so far has raised some skepticism among investors. A study released in August showed that orforglipron could help patients lose an average of about 12% of their body weight. Wall Street had been expecting more; Lilly's injectable drug Zepbound produced weight loss of as much as 21%, and Novo Nordisk has achieved 15% weight loss percentages for both oral and injectable versions of its Wegovy medication. https://www.fiercebiotech.com/biotech/eli-lillys-orforglipron-bests-farxiga-padding-oral-glp-1-case-pair-phase-3-diabetes-wins XX XX UF Health Cancer Center researchers have found a surprising culprit behind common health problems such as obesity, diabetes and fatty liver disease: silent genetic glitches in the blood system that occur naturally as people age. The findings, published in the Journal of Clinical Investigation, mean that in the future, simple blood tests could be developed to identify people most at risk early on, helping prevent chronic illnesses and cancer through strategies like diet or lifestyle changes. As people age, stem cells in the bone marrow that produce blood cells gradually accumulate mutations in their DNA. Most mutations don't cause any issues, but sometimes blood stem cells with a mutation can start crowding out their peers. Called clonal hematopoiesis, this condition affects about 10% of older people and is associated with an increased risk of blood cancers like leukemia. It's also linked to a higher risk of obesity and diabetes. But the prevailing thinking was that obesity and related conditions promoted blood cell changes, not the other way around. The new study reverses that. The implications could be far-reaching, particularly as obesity has now overtaken smoking as the most significant and preventable risk factor for cancer. The team is studying how the mutations drive disease. Next, they plan to test how drugs like those commonly used to treat diabetes and new popular weight loss drugs might help reverse or prevent diseases caused by blood cell changes. https://medicalxpress.com/news/2025-10-hidden-blood-mutations-obesity-diabetes.html XX A new ultra rapid insulin continues to move forward. A phase 3 clinical trial of BioChaperone Lispro (liss-pro) conducted in China found it safe and effective compared with Humalog along with a significant reduction of the rise of blood glucose after a test meal. These results complete and confirm the positive outcomes previously obtained with THDB0206 injection in people with Type 2 Diabetes It combines Adocia's proprietary BioChaperone® technology with insulin lispro, the active ingredient in the standard of care, Humalog® (Eli Lilly). This innovative formulation acts significantly faster https://pharmatimes.com/news/ultra-rapid-insulin-shows-promise-in-phase-3-trial-for-type-1-diabetes/ Poor blood sugar control in adolescent patients with type 1 diabetes (T1D) may be associated with a higher risk of neuropathy in adulthood, according to recent research from the University of Michigan.1 The study included children diagnosed with T1D between 1990-1992 who were recruited into the Cognition and Longitudinal Assessment of Risk Factors over 30 Years cohort study in Australia. Investigators collected HbA1c from medical records, and microvascular complications were assessed through self-reports, clinical screenings, retinal photographs, and urinary albumin-creatinine testing.3 A total of 30 children were recruited from the original cohort with a mean diagnosis age of 2.9 years. After an average of 29.7 years (standard deviation [SD]: 3.9 years), 33% of participants (n = 13) developed neuropathy, 63% (n = 19) developed diabetes-related eye disease, and 10% (n = 3) developed neuropathy.3 Mean HbA1c estimates during adolescence (9% [74.9 mmol/mol]; 95% CI, 8.6-9.3 [70.5-78.1]) were substantially higher than childhood (8.2% [66.1 mmol/mol]; 95% CI, 7.8-8.5 [61.7-69.4]; P
Human resources (HR) administrative overload is a hidden drain on productivity and profits for small and medium-sized enterprises (SMEs) across Ireland. That is according to The Irish SME HR Report 2025, released today by Ireland's leading HR platform provider, HRLocker, which surveyed 400 SMEs in August. The findings reveal that organisations are, on average, spending nine hours per week - equivalent to 58.5 days each year - on manual HR administration tasks. Widespread inefficiencies and frustration The report indicates that this significant time, budget and engagement sink, which equates to 22% of a full-time employee's work week, speaks to widespread inefficiencies. Findings suggest that nearly half (48%) of SMEs spend even more than the average nine hours on manual tasks, with some losing over 16 hours weekly. Based on a 40-hour work week at the national average rate of €51,000, these companies are incurring costs exceeding €22,000 per year. Further, a concerning three-quarters (73%) of respondents frequently enter the same employee data multiple times, indicating a clear waste of effort due to duplication. Organisations across all industries report duplication rates at 70% or above, signifying the prevalence of the issue. However, the problem is particularly pronounced in the Retail & Wholesale sector, where 83% report issues with duplicated efforts. The research also reveals admin drag as a major source of frustration for HR professionals, with 85% agreeing that time spent on manual processing is not an effective use of their time. The findings suggest that the disproportionate time spent on low-value tasks is taking away from more strategic, people-centred initiatives. In fact, most feel they lack the time required to build a positive company culture (84%) and the opportunity to ensure a good employee experience (72%). Smaller SMEs (20-49 employees) spend slightly more time on manual processing, averaging 9.3 hours per week, compared to those with 50-99 employees (8.9 hours) and 100-249 employees (8.8 hours). Still, the relatively equal distribution across SME sizes shows that manual processing hours do not scale in line with the number of employees, implying that a certain level of admin is inherent to all operations. However, as the report indicates, larger companies are more likely to have efficient processes and specialised tools in place that cut down excessive manual work. A clear need for better tools and processes The findings underscore a critical need for better tools and streamlined processes to alleviate this administrative burden. The data indicates that companies utilising fully fit-for-purpose HR information systems (HRIS) are significantly less likely to experience data duplication (69%) than those mainly using manual processes or a mix of generic tools (75%), demonstrating the tangible benefits of investing in appropriate technology. "Our research clearly exposes a silent, yet significant, challenge facing Irish SME owners and leaders in their HR operations," says Crystel Robbins Rynne, CEO of HRLocker. "Despite advancements in technology, valuable time and resources are being diverted to repetitive, low-value administrative tasks, such as updating employee records, attendance tracking, and leave management. This not only impacts the bottom line but also prevents HR teams from focusing on strategic initiatives that drive employee engagement, bolster talent attraction and retention, and boost business growth." HRLocker's The Irish SME HR Report 2025 provides crucial insights for SME owners and leaders in Ireland looking to reclaim lost time, reduce unnecessary costs, and empower their HR teams to contribute more strategically to business success. It is available to download from: https://www.hrlocker.com/downloads/irish-sme-hr-report-2025 See more stories here.
Minority in Parliament has criticized the Government and the Attorney General for what it describes as empty rhetoric and a waste of everyone's time. Member of Parliament for the Effia Constituency, Isaac Boamah-Nyarko, expressed shock that the Minister of Justice and Attorney General, Dr. Dominic Akuritinga Ayine, remains in office despite accusing several NPP appointees of being involved in corruption and related activities
Goldylocks Productions presents Joyful Findings with Melissa ParksMelissa Parks is an Earth Angel, a talented Psychic Trance Medium, Angelic Guided Healer, Reiki Master, Spiritual Advisor and Spiritual Teacher. As a child she was able to see and communicate with the Spirit World but was shut down and told to ignore her gifts. Most of her life was filled with hurt, anger, and pain. It wasn't until a “voice” told her she must forgive her childhood abuser that her heart had truly opened, and her Spiritual Journey began.Once she embraced her True Self and her connection to God's Divine Beings, she understood her life's plan. She now spreads Love and Light, giving Guidance and Healing to all who seek it. Whether in a reading or healing session she opens to Past Loved Ones, Angels, Guides, and many Multi-Dimension Healers to bring forth powerful messages of Guidance and Healing.http://www.iammelissaparks.com Special Guest: Myrna Lou Goldbaum, Master PalmistMyrna Lou teaches classes in Palmistry with an insightful explanation of the lines and symbols on the palm and is accurate, compassionate and listens. The modality employed is referred to as Asian Palmistry. Her palmistry services have been booked for parties, private and corporate groups and for individual readings. Entertainer, guest lecturer, can hold seminars and workshops, is a participant in numerous psychic fairs and has been a guest on radio and television programs nationally. She has corresponded with people in 93 countries for palm readings. Currently the only Master Palmist in the world who can guest on a radio show and read palms live from scanned computer palm prints. She is a vendor in Psychic Fairs, Book Fairs and in Trade Shows and works for entertainment Agencies at corporate events.As of 5/15/2024I have documented and read 59,900 palms. Individuals mail photocopies or scan palms to my email address; they are interpreted with a 90-95% accuracy rate and a 4-5 page report is generated.https://www.myrnalou.comGoldylocks Productions: http://www.goldylocksproductions.com Receive links and updates for our Shows, Special Events and Sales! Subscribe to The Goldylocks Zone Blog: https://www.whitesagewoman.me Join us on Telegram: https://t.me/goldylocksproductions Hosted on Acast. See acast.com/privacy for more information.
Does smoking cannabis cause lung cancer? Does sitting for long periods of time cause blood clots? Professor Richard Beasley answers these questions in his national lecture tour.
Dr. Robin Carhart-Harris is a neuroscientist and professor of neurology and psychiatry at the University of California, San Francisco, where he leads the Psychedelics Division. He is internationally recognized for pioneering research on psychedelics, brain function, and mental health. His studies have revealed how substances like psilocybin and LSD can “reset” brain networks and offer therapeutic potential for conditions such as depression and anxiety. Dr. Carhart-Harris is a leading voice in the renaissance of psychedelic science, making groundbreaking neuroscience accessible to both scientific and public audiences.In our conversation we discuss:(00:00) Misunderstandings people have about psychedelics(02:27) Differentiating psychedelics from drugs like ketamine, MDMA(08:39) Why people group all drugs together(14:57) History of ancestral use of psychedelics(21:46) Visions or insights during dark retreat(23:17) Biohacks for psychedelic experiences without compounds(29:10) Natural vs synthetic psychedelics and effects(32:28) Albert Hoffman's discovery of LSD(37:45) Findings from legal LSD human studies(45:55) Comparing SSRIs and psychedelics for depression(46:27) Clarification on psilocybin as treatment(48:49) Qualitative vs quantitative measures in trials(51:34) No difference between SSRIs and psychedelics?(54:21) Hesitations about psychedelics despite effectiveness(54:56) Why clinicians hesitate to provide both options(58:04) Downsides of SSRIs versus psychedelics(1:03:46) Dependency risk of SSRIs vs psychedelics(1:07:49) Personality traits suited for SSRIs vs psychedelics(1:12:54) Microdosing versus single high psychedelic doses(1:14:48) Placebo or real effects of microdosing(1:18:57) Brian Johnson's blueprint and psychedelics(1:20:32) Psychedelics and potential longevity benefits(1:26:01) Key takeaway and misconception to forget(1:29:04) Where to follow for book updatesLearn more about Dr. Robin:https://en.wikipedia.org/wiki/Robin_Carhart-Harrishttps://profiles.ucsf.edu/robin.carhart-harris@CarhartharrislabWatch full episodes on: https://www.youtube.com/@seankimConnect on IG: https://instagram.com/heyseankim
Send us an email @ info@parentcoachesunleashed.com In this episode of Parent Coaches Unleashed, hosts Carrie Wiesenfeld and Jessica Anger examine one of the most relevant issues in contemporary parenting: “sharenting.” The term refers to the practice of parents sharing photographs, stories, and personal moments about their children on social media. While such sharing often stems from pride, affection, and the desire to celebrate milestones, the hosts urge listeners to reflect on the potential risks to children's privacy and emotional well-being.The Double-Edged Nature of SharentingAnger and Wiesenfeld discuss how sharenting creates a permanent digital footprint that may follow children into adulthood. They emphasize that what seems like a harmless post today could have unforeseen consequences in the future, particularly as technology evolves and data becomes more accessible through artificial intelligence and digital archiving. The episode encourages parents to seek consent from their children before sharing personal images or details and to remain informed about the ethical and safety implications of social media use.Navigating Nostalgia and the Empty NestBeyond the digital dimension, the hosts explore the emotional journey of parenthood. As children grow older, parents often experience a profound sense of nostalgia—cherishing memories of earlier years while confronting the challenges of letting go. Anger and Wiesenfeld candidly discuss the transition to empty nesting, highlighting how this stage can bring both loss and renewal. Their reflections remind parents of the importance of living fully in the present rather than curating the past through online images.Fostering Connection Through ConversationThe episode concludes with actionable insights for nurturing stronger family relationships. The hosts stress the importance of open-ended questions when communicating with teenagers, as these invite authentic dialogue and deeper emotional connection. They advocate for device-free family time, encouraging parents to prioritize genuine engagement over digital distractions. Ultimately, they argue that meaningful relationships are built not on perfectly documented moments but on attentive presence and mutual respect.TakeawaysSharenting can create lasting privacy and emotional risks for children.Parents share from love and pride, but should weigh long-term consequences.Consent and digital awareness are essential in today's connected world.Understanding the impact of AI and data permanence can guide safer online habits.Mindfulness and presence enrich family life more than social validation.Open-ended communication fosters trust and connection with teens.Nostalgia can serve as both a comfort and a reminder of life's fleeting stages.Boundaries and autonomy empower children to shape their digital identities.
In this episode of The Cyber Threat Perspective, we highlight the pentest findings that, frankly, have no business showing up in 2025. From accounts with weak passwords and no MFA to plaintext credentials on file shares, we break down the common misconfigurations and oversights that attackers still abuse, despite years of seeing the same issues over and over again. If you're an IT admin or security leader, this episode is your checklist of what to fix yesterday.Blog: https://offsec.blog/Youtube: https://www.youtube.com/@cyberthreatpovTwitter: https://x.com/cyberthreatpov Follow Spencer on social ⬇Spencer's Links: https://go.spenceralessi.com/links Work with Us: https://securit360.com | Find vulnerabilities that matter, learn about how we do internal assume breach pentesting here.
Welcome back to another episode of the unSeminary podcast. Today we're joined by Dr. Warren Bird—author, researcher, and one of the most trusted voices in church leadership studies. Warren has co-authored over 35 books for pastors and church leaders, including Hero Maker, Better Together, Next, Resilience Factor, and his newest, Becoming a Future-Ready Church. Known […]
In this bonus episode, Natalie Brown explores some of the most compelling recent research in sound healing. From tuning forks and Tibetan singing bowls to frequency-specific interventions and cellular-level vibration, these studies highlight the scientific insights behind sound, frequency, and vibration for mental, emotional, and physical well-being. Natalie Brown, host of Sounds Heal Podcast: http://www.soundshealstudio.com http://www.facebook.com/soundshealstudio http://www.instagram.com/nataliebrownsoundsheal http://www.youtube.com/soundshealstudio Music by Natalie Brown Featured Studies & Links: 1. Triple OM Clinical Study Using Tuning Fork Sound Healing https://www.soundtravels.co.uk/a-Triple_OM_Clinical_Study_using_Tuning_Fork_Sound_Healing-3807.aspx 2. Differential Effects of Sound Interventions Tuned to 432 Hz or 443 Hz on Cardiovascular Parameters in Cancer Patients https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/s12906-025-04758-5 3. The Implications of Vibration and Sound Therapy in Modern Medicine https://www.scholarlyreview.org/article/124889.pdf 4. Effects of Tibetan Singing Bowl Intervention on Psychological and Physiological Outcomes https://www.mdpi.com/2227-9032/13/16/2002 5. Exploring the Healing Power of Singing Bowls https://pubmed.ncbi.nlm.nih.gov/37532602/ 6. Vibratory Frequencies of Cells in Healthy and Disease States https://www.researchgate.net/publication/359600326_Sound_Therapy_Vibratory_Frequencies_of_Cells_in_Healthy_and_Disease_States
In this episode we discussed a recently released research snapshot titled “Utah Women and Mental Health: A 2025 Update.” This research provides an updated overview of women's mental health in Utah, drawing on recent statewide data and analysis to better understand current rates, contributing factors, and efforts to improve well-being for girls, women, and their families. Findings show that Utah ranks second in the nation for adults living with any mental illness, with women reporting depression at nearly double the rate of men. The research also highlights underlying factors such as adverse childhood experiences, sexual violence and domestic abuse, and gender-based discrimination, all of which significantly impact women's mental and behavioral health. Together, these insights offer a clearer picture of the barriers Utah women face and set the stage for strategies and solutions we'll explore further.Dr. Susan Madsen, a Professor of Organizational Leadership in the Jon M. Huntsman School of Business at Utah State University and the Founding Director of the Utah Women & Leadership Project and A Bolder Way Forward, is joined by Sadie Wilde, the lead author of the report and a Professional Practice Assistant Professor at Utah State University Extension. Support the show
Wastewater discharged from 59 per cent of Ireland's existing treatment plants failed to regularly meet EPA standards. That's according to a new report from the Environment protection agency. Shane discusses the findings with Noel Byrne, Programme Manager in the EPA's Drinking Water and Wastewater Enforcement team,
Nearly two-thirds of bar and retail workers have faced verbal abuse at work, over a quarter have been threatened, and more than one in ten have been assaulted. That's according to a new survey from Mandate Trade Union. Shane discusses these findings with Jim Fuery, Mandate Trade Union's Assistant General Secretary.
It's In the News.. a look at the top headlines and stories in the diabetes community. This week's top stories: Sanofi lowers prices, oral pill for T1D prevention studied, updates from Medtronic, Tandem, and Sequel Med Tech, falsely lower A1Cs (and why that happens), Biolinq gets FDA okay for micro-needle CGM and more! Find out more about Moms' Night Out Please visit our Sponsors & Partners - they help make the show possible! Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com) Omnipod - Simplify Life Learn about Dexcom Check out VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Twitter Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com Reach out with questions or comments: info@diabetes-connections.com Episode transcription with links: Hello and welcome to Diabetes Connections In the News! I'm Stacey Simms and every other Friday I bring you a short episode with the top diabetes stories and headlines happening now. XX French drugmaker Sanofi says it would offer a month's supply of any of its insulin products for $35 to all patients in the U.S. with a valid prescription, regardless of insurance status. The program, originally meant for uninsured diabetes patients, would now include those with commercial insurance or Medicare, the drugmaker said. Patients will be able to purchase any combination, type, and quantity of Sanofi insulins with a valid prescription for the fixed monthly price of $35, starting January 1. Lilly and Novo also have similar programs through which they offer insulin products for $35 a month for U.S. patients regardless of whether the patients have insurance. There is no law at work here – the only legislation that has changed the price of insulin came with the Inflation Reduction Act in 2022 with the Medicare cap. Helping lower the cost here, biosimilars hitting the market and the huge profitability for GLP-1 drugs for Novo and Lilly https://www.reuters.com/business/healthcare-pharmaceuticals/sanofi-offer-all-insulin-products-35-per-month-us-2025-09-26/ XX A pill typically prescribed for rheumatoid arthritis and alopecia might help slow the progression of type 1 diabetes, a new study says. Baricitinib (bare-uh-SIT-nib) safely preserved the body's own insulin production in people newly diagnosed with type 1 diabetes.. and their diabetes started progressing once they stopped taking baricitinib, results show. They produced less insulin and had less stable blood sugar levels. Baricitinib works by quelling signals in the body that spur on the immune system, and is already approved for treating autoimmune conditions such as rheumatoid arthritis, ulcerative colitis and alopecia, researchers said. “Among the promising agents shown to preserve beta cell function in type 1 diabetes, baricitinib stands out because it can be taken orally, is well tolerated, including by young children, and is clearly efficacious,” Waibel said. “We are hopeful that larger phase III trials with baricitinib are going to commence soon, in people with recently diagnosed type 1 diabetes as well as in earlier stages to delay insulin dependence,” she added. “If these trials are successful, the drug could be approved for type 1 diabetes treatment within five years.” Findings presented at medical meetings should be considered preliminary until published in a peer-reviewed journal. https://www.usnews.com/news/health-news/articles/2025-09-23/pill-effective-in-slowing-type-1-diabetes-progression XX An existing transplant drug has shown promise in slowing the progression of type 1 diabetes in newly diagnosed young people, potentially paving the way for the first therapy that modifies the disease after diagnosis. The Drug, called ATG, is currently used together with other medicines to prevent and treat the body from rejecting a kidney transplant. It can also be used to treat rejection following transplantation of other organs, such as hearts, gastrointestinal organs, or lungs. The researchers studied 117 people aged five to 25, who'd been diagnosed with type 1 diabetes within the past three to nine weeks. The participants were from 14 centers across eight European countries and were randomized to be given different doses of ATG (0.1, 0.5, 1.5, or 2.5 mg/kg) or a placebo. ATG was given as a two-day intravenous (IV) infusion. The main goal was to see how well the pancreas could still make insulin after 12 months, measured by C-peptide levels during a special meal test. C-peptide is released into the blood along with insulin by the pancreas. The findings are promising, showing that ATG, even at a relatively low dose, can slow the loss of insulin-producing cells in young people newly diagnosed with type 1 diabetes. The lower dose also caused fewer side effects, making it a more practical option. https://newatlas.com/disease/antithymocyte-globulin-newly-diagnosed-type-1-diabetes/ XX The FDA has delayed its feedback on Lexicon Pharmaceuticals' application to bring Zynquista (sotagliflozin) to people with type 1 diabetes. The agency had planned to respond this month but will now wait until the fourth quarter after reviewing new data from ongoing studies. Zynquista, an oral drug meant to be used with insulin, has already been approved for heart failure (marketed as Inpefa). But in type 1 diabetes, it faces safety concerns: last year an FDA advisory committee voted 11–3 that its benefits don't outweigh the increased risk of diabetic ketoacidosis (DKA). The FDA later issued a complete response letter rejecting the drug. Lexicon is still pushing forward, hoping its additional submissions will strengthen Zynquista's case for type 1 diabetes approval. https://www.biospace.com/fda/after-fda-rejection-lexicons-type-1-diabetes-drug-hit-with-another-regulatory-delay XX A common but often undiagnosed genetic condition may be causing delays in type 2 diabetes diagnoses and increasing the risk of serious complications for thousands of Black and South Asian men in the UK—and potentially millions worldwide. A new study found around one in seven Black and one in 63 South Asian men in the UK carry a genetic variant known as G6PD deficiency. Men with G6PD deficiency are, on average, diagnosed with type 2 diabetes four years later than those without the gene variant. But despite this, fewer than one in 50 have been diagnosed with the condition. G6PD deficiency does not cause diabetes, but it makes the widely used HbA1c blood test—which diagnoses and monitors diabetes—appear artificially low. This can mislead doctors and patients, resulting in delayed diabetes diagnosis and treatment. The study found men with G6PD deficiency are at a 37% higher risk of developing diabetes-related microvascular complications, such as eye, kidney, and nerve damage, compared to other men with diabetes. "This study highlights important evidence that must be used to tackle these health inequalities and improve outcomes for Black communities. Preventative measures are now needed to ensure that Black people, especially men, are not underdiagnosed or diagnosed too late." https://medicalxpress.com/news/2025-09-hidden-genetic-delay-diabetes-diagnosis.html XX Novo Nordisk today announced the resubmission of its Biologics License Application (BLA) to the US Food and Drug Administration (FDA) for Awiqli® (insulin icodec) injection, a once-weekly basal insulin treatment for adults living with type 2 diabetes. If approved, Awiqli® would become the first once-weekly basal insulin available in the United States, providing an alternative to daily basal insulin injections for adults living with type 2 diabetes. The resubmission is based on results from the ONWARDS type 2 diabetes phase 3a program for once-weekly Awiqli® which is comprised of five randomized, active-controlled, treat-to-target clinical trials in approximately 4,000 adults with type 2 diabetes. The clinical program evaluated Awiqli® vs. daily basal insulin and the primary endpoint in these trials was change in A1C from baseline.1-5 Awiqli® is approved in the EU, along with 12 additional countries. In addition, regulatory filings have been completed in several other countries, with further regulatory decisions expected in 2025. XX Interesting news from Sequel Med Tech – they've signed an agreement with Arecor to pair the twiist pump with AT278 an ultra-concentrated (500U/mL), ultra-rapid insulin in development. They also have a deal with Medtronic to develop insulin for new pumps. This insulin isn't yet approved, it's 5 times stronger than standard fast acting it's hoped that a clinical study will begin next year. Arecor says its insulin could potentially be the only option capable of enabling and catalyzing the next generation of longer-wear and miniaturized automated insulin delivery systems. https://www.drugdeliverybusiness.com/sequel-arecor-develop-rapid-insulin-twiist/ XX Tandem Diabetes Care announes its t:slim X2™ insulin pump with Control-IQ+ automated insulin delivery (AID) technology is now cleared for use with Eli Lilly and Company's Lyumjev® (insulin lispro-aabc injection) ultra-rapid acting insulin in the United States (U.S.). – The t:slim X2 insulin pump with Control-IQ+ technology is now cleared for use with Lyumjev for people with type 1 diabetes ages 2 and above and all adults with type 2 diabetes. The companies are continuing to work toward securing Lyumjev compatibility for the Tandem Mobi pump. https://hitconsultant.net/2025/09/29/tandem-diabetes-cares-tslim-x2-pump-cleared-for-use-with-lillys-ultra-rapid-lyumjev-insulin/ XX You can now place your order for the MiniMed™ 780G system with the Instinct sensor, made by Abbott. And if you are already a MiniMed 780G user, you can place an upgrade order today. This is a 15 day wear sensor, with no transmitter or overtape required. It looks the same at other Abbot sensors such as the Libre but is proprietary to Medtronic. Shipments are scheduled to start in November. https://www.drugdeliverybusiness.com/medtronic-launches-minimed-780g-instinct-abbott/ XX The global type 1 diabetes (T1D) burden continues to increase rapidly driven by rising cases, ageing populations, improved diagnosis and falling death rates. , The study estimates that T1D will affect 9.5 million people globally in 2025 (up by 13% since 2021), and this number is predicted to rise to 14.7 million in 2040. However, due to lack of diagnosis and challenges in collecting sufficient data, the actual number of individuals living with T1D is likely much higher, researchers say. In fact, they estimate that there are an additional 4.1 million 'missing people' who would have been alive in 2025 if they hadn't died prematurely from poor T1D care, including an estimated 669,000 who were not diagnosed. This is particularly true in India, where an estimated 159,000 people thought to have died from missed diagnoses. The study predicts that 513,000 new cases of T1D will be diagnosed worldwide in 2025, of which 43% (222,000) will be people younger than 20 years old. Finland is projected to have the highest incidence of T1D in children aged 0-14 years in 2025 at around 64 cases per 100,000. The substantial increases in T1D forecasts between 2025 and 2040 underscore the urgent need for action. As co-author Renza Scibilia from Breakthrough T1D explains, "Early diagnosis, access to insulin and diabetes supplies, and proper healthcare can bring enormous benefits, with the potential to save millions of lives in the coming decades by ensuring universal access to insulin and improving the rate of diagnosis in all countries." The authors note some important limitations to their estimates, including that while the analysis uses the best available data, predictions are constrained by the lack of accurate data in most countries-highlighting the urgent need for increased surveillance and research. They also note that data on misdiagnosis and adult populations remain limited, and the analysis assumes constant age-specific incidence and mortality over time. Furthermore, incidence data from the COVID-19 period were excluded from part of the modelling to avoid bias. Future updates are expected to improve as new data become available and applied. https://www.news-medical.net/news/20250919/New-study-warns-of-millions-of-undiagnosed-and-missing-people-with-type-1-diabetes.aspx XX A new study has found that semaglutide — the active ingredient found in some GLP-1 medications prescribed for diabetes and to aid weight loss — may help protect the eyes from diabetic retinopathy. Researchers estimate that as much as 40% of all people with diabetes also have diabetic retinopathy — a potentially blinding eye condition caused by blood vessel damage in the eye's retina. There is currently no cure for diabetic retinopathy. The condition is often managed through injections of anti-VEGF medications into the eye, surgery, and blood sugar monitoring and control. For this lab-based study, researchers used samples of human retinal endothelial cells that were treated with different concentrations of semaglutide. The cells were then placed in a solution with both a high glucose level and high level of oxidative stress — where there is an imbalance of antioxidants and free radicals — for 24 hours. Past studies show that oxidative stress plays a role in the formation of diabetic retinopathy. At the study's conclusion, researchers found that the retinal cells treated with semaglutide were twice as likely to survive than cells that were untreated. Additionally, the treated cells were found to have larger stores of energy. Scientists also found that three markers of diabetic retinopathy were decreased in the semaglutide-treated retinal cells. First, the levels of apoptosis — a form of cell death — decreased from about 50% in untreated cells to about 10% in semaglutide-treated cells. The production of the free radical mitochondrial superoxide decreased from about 90% to about 10% in the treated retinal cells. Researchers also found the amount of advanced glycation end-products — harmful compounds that can collect in people with diabetes and are known to cause oxidative stress — also decreased substantially. Lastly, scientists reported that the genes involved in the production of antioxidants were more active in the semaglutide-treated cells when compared to untreated cells. Researchers believe this is a sign that semaglutide may help repair damage to the retinal cells. “Our study did not find that these drugs harmed the retinal cells in any way — instead, it suggests that GLP1-receptor agonists protect against diabetic retinopathy, particularly in the early stages,” Ioanna Anastasiou, PhD, molecular biologist and postdoctoral researcher at the National and Kapodistrian University in Greece, and lead author of this study, said in a press release. “Excitingly, these drugs may be able to repair damage that has already been done and so improve sight. Clinical trials are now needed to confirm these protective effects in patients and explore whether GLP-1 receptor agonists can slow, or even halt, the progression of this vision-robbing condition.” https://www.medicalnewstoday.com/articles/ozempic-semaglutide-may-help-protect-against-diabetes-related-blindness-retinopathy XX Biolinq has received De Novo Classification from the U.S. Food and Drug Administration for its lead product, Biolinq Shine, a patch on the forearm that provides real-time glucose feedback through a primary color-coded LED display, visible with or without a phone. This one is tricky – it's called a needle free CGM but it also says it uses micro needles. By the way, De Novo isn't exactly the same as what we think of for FDA approval for medical devices. It's not as rigorous but it's a streamlined route for novel, low to moderate risk devices with no existing equivalent. We'll see how this one turns out. https://www.hmenews.com/article/biolinq-s-multi-function-biosensor-receives-fda-de-novo-classification
John Maytham is joined by Francois Viljoen, systemic investigations manager at the Tax Ombud’s Office to discuss how SARS investigators failed eFiling hijacking victims. Presenter John Maytham is an actor and author-turned-talk radio veteran and seasoned journalist. His show serves a round-up of local and international news coupled with the latest in business, sport, traffic and weather. The host’s eclectic interests mean the program often surprises the audience with intriguing book reviews and inspiring interviews profiling artists. A daily highlight is Rapid Fire, just after 5:30pm. CapeTalk fans call in, to stump the presenter with their general knowledge questions. Another firm favourite is the humorous Thursday crossing with award-winning journalist Rebecca Davis, called “Plan B”. Thank you for listening to a podcast from Afternoon Drive with John Maytham Listen live on Primedia+ weekdays from 15:00 and 18:00 (SA Time) to Afternoon Drive with John Maytham broadcast on CapeTalk https://buff.ly/NnFM3Nk For more from the show go to https://buff.ly/BSFy4Cn or find all the catch-up podcasts here https://buff.ly/n8nWt4x Subscribe to the CapeTalk Daily and Weekly Newsletters https://buff.ly/sbvVZD5 Follow us on social media: CapeTalk on Facebook: https://www.facebook.com/CapeTalk CapeTalk on TikTok: https://www.tiktok.com/@capetalk CapeTalk on Instagram: https://www.instagram.com/ CapeTalk on X: https://x.com/CapeTalk CapeTalk on YouTube: https://www.youtube.com/@CapeTalk567 See omnystudio.com/listener for privacy information.
Goldylocks Productions presents Joyful Findings with Melissa ParksMelissa Parks is an Earth Angel, a talented Psychic Trance Medium, Angelic Guided Healer, Reiki Master, Spiritual Advisor and Spiritual Teacher. As a child she was able to see and communicate with the Spirit World but was shut down and told to ignore her gifts. Most of her life was filled with hurt, anger, and pain. It wasn't until a “voice” told her she must forgive her childhood abuser that her heart had truly opened, and her Spiritual Journey began.Once she embraced her True Self and her connection to God's Divine Beings, she understood her life's plan. She now spreads Love and Light, giving Guidance and Healing to all who seek it. Whether in a reading or healing session she opens to Past Loved Ones, Angels, Guides, and many Multi-Dimension Healers to bring forth powerful messages of Guidance and Healing.http://www.iammelissaparks.com Melissa's Sponsors: Marcia Morse with Feng Shui My SpaceFeng shui literally translates from Chinese as "wind" (feng) and water ("shui"). It's the art of arranging buildings, objects, space, and life to achieve harmony and balance. The philosophy of feng shui is the practice of arranging the pieces in living spaces in order to create balance with the natural world. The goal is to harness energy forces and establish harmony between an individual and their environment. Contact Feng Shui Specialist, Marcia Morse, to assist you in bringing in more Harmony and Peace into your home, property, or business space! Marcia is also a Realtor and can assist you in finding your New Home in the Sarasota, Florida area.https://www.fengshuimyspace.com http://www.sarasotasunset.comLola Blue Living https://lolablueliving.com Goldylocks Productions: http://www.goldylocksproductions.com Receive links and updates for our Shows, Special Events and Sales! Subscribe to The Goldylocks Zone Blog: https://www.whitesagewoman.me Join us on Telegram: https://t.me/goldylocksproductions Hosted on Acast. See acast.com/privacy for more information.
Dr. Shau-Ming Wei (National Institute of Mental Health, Bethesda, MD) joins AJP Audio to discuss a replication study looking at impact of hormone addback to a hormone suppression regimen for the treatment of premenstrual dysphoric disorder. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the rest of the October issue of the Journal. 00:34 Wei interview 02:59 PMDD 04:22 Up and downsides of hormone suppression 05:52 Hormone addback 07:15 Limitations of the current study 08:38 Further research 10:42 Kalin interview 10:58 Wei et al. 15:25 Sanacora et al. 20:07 Whittle et al. 23:06 Cooper et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
Let's dive back into this Kawhi Leonard story. Pablo Torre continues to uncover even more details from this Steve Ballmer, Aspiration, Clippers, Kawhi story. It never seems to end! But now Kawhi had to answer some media questions. (19:30) The Clippers weren't done yet. A new patch deal with Rwanda? Huh? (25:10) Steve Cohen finally tweeted. What a guy. What an owner. Then we had David Stearns talk about the Mets season. And sorry Mets fans, but Carlos Mendoza is coming back. (37:30) Dolphins got a win. But, they lost Tyreek Hill, for likely a long time. Devastating injury. (44:30) NPPOD. (46:30) LeBron James met with media yesterday. Is this it for him? Learn more about your ad choices. Visit podcastchoices.com/adchoices
Let's dive back into this Kawhi Leonard story. Pablo Torre continues to uncover even more details from this Steve Ballmer, Aspiration, Clippers, Kawhi story. It never seems to end! But now Kawhi had to answer some media questions. (19:30) The Clippers weren't done yet. A new patch deal with Rwanda? Huh? (25:10) Steve Cohen finally tweeted. What a guy. What an owner. Then we had David Stearns talk about the Mets season. And sorry Mets fans, but Carlos Mendoza is coming back. (37:30) Dolphins got a win. But, they lost Tyreek Hill, for likely a long time. Devastating injury. (44:30) NPPOD. (46:30) LeBron James met with media yesterday. Is this it for him? Learn more about your ad choices. Visit podcastchoices.com/adchoices
Too many organizations treat crisis simulations and tabletop exercises as the finish line, when in reality they're just the starting point. In this episode, Rob Burton explores why the real value lies in what comes after the exercise: prioritizing findings, assigning ownership, keeping leadership engaged, and measuring improvement. Rob shares common challenges resilience leaders face,... The post Closing the Gap: Turning After-Action Findings into Real Resilience appeared first on PreparedEx.
Hometown Radio 09/26/25 6p: The City of SLO rejects recent Grand Jury findings
Send us a textJoin your favorite truth seekers (if you can get past the horrible background noise lol!) as they break down the latest relevant news stories and discuss Sabrina Wallace and her findings around the WBAN Support the show@truthorpropaganda Truthorpropaganda@gmail.com
Join Badlands Media for special coverage of President Trump announcing significant medical and scientific findings for America's children
President Donald Trump will sign the TikTok deal with China this week, a senior White House official said on Monday. Under the deal, Oracle will serve as the security provider, overseeing how U.S. user data is stored within Oracle's systems and how content recommendation algorithms operate.Trump also said his administration would make an announcement about its autism findings on Monday, though he declined to offer specifics. Autism diagnoses in the United States have increased significantly since 2000. Health Secretary Robert F. Kennedy Jr. has said that the United States is in the grip of an “autism epidemic” fueled by “environmental toxins.”
In this episode, Dr. David Jockers explains the critical role protein plays in burning fat and building muscle. You'll learn how protein stabilizes blood sugar, supports brain function, and helps maintain lean body mass as you age. He also highlights how protein reduces cravings and promotes fat burning, with a focus on amino acids like leucine for muscle growth. Plus, discover how protein boosts energy and mental clarity. Dr. Jockers shares practical tips on protein intake based on body weight and activity level, emphasizing the benefits of eating within a restricted time window. In This Episode: 00:00 Introduction to Protein and Health Risks 00:20 Podcast Welcome and Episode Overview 02:53 Importance of Protein for Health 04:34 Protein Types and Their Benefits 05:36 Leucine Threshold and Protein Intake Recommendations 11:26 Protein Intake by Weight and Meal Timing 17:10 Conclusion and Final Thoughts Struggling with stress, low energy, or poor sleep? Magnesium Breakthrough is designed to help calm your mind, enhance focus, and improve sleep quality with all seven forms of magnesium. Take advantage of an exclusive offer by visiting bioptimizers.com/jockers and using the promo code Jockers at checkout to save 10%. Don't forget to subscribe for even more discounts and free gifts with your monthly supply! If you're serious about reducing your toxic load, I highly recommend upgrading to the P600 ceramic cookware. It's 100% free from Teflon, PFAS, and plastic coatings, ensuring a non-toxic cooking experience. Right now, you can get it for 50% off, plus an extra 20% off with the code SAFE20 at checkout! Don't miss this limited-time offer—head to chefsfoundry.com/jockers to claim your discount today! Support your skin from the inside out with Clearstem, the acne brand that connects internal and external skincare without pore-clogging ingredients. Pair their best-selling Mind Body Skin hormonal acne supplement with Clearstem's clinically effective topicals for results that last. Get 15% off your order today at clearstem.com/drjockers using code DRJOCKERS at checkout. “Protein helps stabilize blood sugar, boost energy, and improve brain function — it's crucial for overall health!” ~ Dr. Jockers Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: Use code JOCKERS at bioptimizers.com/jockers to save 10% Use code Safe20 at chefsfoundry.com/jockers Get 15% off your order today at clearstem.com/drjockers using code DRJOCKERS Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/
We've all had bad bosses.We might have even been one. At the very least, we've probably let people down who counted on us.We all carry burdens from our past that show up in how we lead. And we're all confronting systems that foster toxic workplace cultures where overwork and blurred boundaries are the norm, spaces that don't feel safe or generative, and where there is little to no accountability.The question we face is simple, but urgent: How do we want to lead?Our leadership can reinforce toxic systems and norms. Or we can learn to recognize our own burdens and do the work to become more aware, adaptable, and flexible. We can create spaces where people feel seen, heard, and valued, even when systems feel unstable or unfair.Because leading is about deciding, in every moment, whether we respond from our burdens or from our values. And my guest today helps us reflect on those choices and decide how we want to lead through her own lived experiences with bad bosses. Mita Mallick is a Wall Street Journal and USA Today bestselling author who is on a mission to fix what's broken in our workplaces. She's a corporate change maker with a track record of transforming businesses and has had an extensive career as a marketing and human resources executive. Mallick is a highly sought-after speaker who has advised Fortune 500 companies and start-ups alike. She is a LinkedIn Top Voice and was named to the Thinkers 50 Radar List. She's a contributor to Harvard Business Review, Fast Company, Adweek, and Entrepreneur. Mallick has been featured in The New York Times, The Wall Street Journal, The Washington Post, Time Magazine, Forbes, Axios, Essence, Cosmopolitan Magazine and Business Insider.Listen to the full episode to hear:Three scenarios where leaders commonly shift into being bad bossesKey reasons why we tolerate bad bosses and what we can do to shift the cultureWhy Mita's 13 archetypal bad bosses persist in our workplacesWhy leaders have to invest time and connection in their team members if they want to retain themWhy another executive coaching program will not fix a truly bad bossThe number one skill leaders can focus on to become a better bossWhy corporate America needs more humility and vulnerabilityLearn more about Mita Mallick:WebsiteConnect on LinkedInReimagine Inclusion: Debunking 13 Myths to Transform Your WorkplaceThe Devil Emails at Midnight: What Good Leaders Can Learn from Bad BossesLearn more about Rebecca:rebeccaching.comWork With RebeccaThe Unburdened Leader on SubstackSign up for the weekly Unburdened Leader EmailResources:EP 102: Toxic Leadership: The True Cost of Workplace Trauma with Mita MallickGive and Take: A Revolutionary Approach to Success, Adam GrantThe Fearless Organization: Creating Psychological Safety in the Workplace for Learning, Innovation, and Growth, Amy C EdmondsonThe Normalization Of Corruption In Organizations, Blake E. Ashforth and Vikas AnandManaging to be ethical: Debunking five business ethics myths, Linda Klebe Treviño and Michael E. BrownExamining the Link Between Ethical Leadership and Employee Misconduct: The Mediating Role of Ethical Climate, David M. Mayer, Maribeth Kuenzi, Rebecca L. GreenbaumThe Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma, Bessel van der Kolk M.D.The Pocket Guide to the Polyvagal Theory: The Transformative Power of Feeling Safe, Stephen W. PorgesPrimal Leadership: Unleashing the Power of Emotional Intelligence, Prof Daniel Goleman PH D, Richard E Boyatzis, and Annie McKeePsychological Conditions of Personal Engagement and Disengagement at Work, William A. KahnEmotional Intelligence: Theory, Findings, and Implications, John D. Mayer, Peter Salovey, David R. CarusoWorking with Emotional Intelligence, Daniel GolemanThe 5Ds of Bystander Intervention - Right To BeEP 52: Charlie Gilkey: Leading With What Matters MostEP 85: Team Habits: Redefining Workplace Dynamics with Charlie GilkeyBig Magic: Creative Living Beyond Fear, Elizabeth GilbertThe Anxious Achiever: Turn Your Biggest Fears Into Your Leadership Superpower, Morra Aarons-MeleSia - UnstoppableThe SopranosBreaking BadFresh Off the BoatThe Fresh Prince of Bel Air
Your Natural Dog with Angela Ardolino - Formerly It's A Dog's Life
In this episode of Your Natural Dog with Angela Ardolino, Angela and Carter sit down with Dr. Joel Ehrenzweig, veterinarian, researcher, and founder of Veterinary Health Research Centers — to talk about the groundbreaking Senior Dog Study they've been running together for the past year. Dr. Ehrenzweig shares why he shifted from a strictly pharmaceutical approach to fully embracing natural medicine late in his career. Angela, Carter and Dr. Ehrenzweig discuss how the Senior Dog Study is helping to validate what holistic practitioners have known for years: that functional mushrooms and natural adaptogens can potentially make a real difference in cognitive health, quality of life, and emotional connection for senior dogs.If you have an aging pup and have ever been told “there's nothing we can do,” this episode will give you hope, real data, and real-life stories showing that there are options. Learn more about the Senior Dog Study. Episode RecapLaunching the Senior Dog Study – Carter shares how they recruited a diverse group of senior dogs experiencing cognitive decline—many from families who believed they had no options left—then tracked behavior, activity, and sleep to build a data-backed picture of progress over the course of the study. (00:31)Validating Centuries of Natural Medicine – Angela shares how rescuing senior dogs inspired her to prove that natural approaches—real food, hemp, mushrooms, and adaptogens—can help aging pets thrive without relying on pharmaceutical “longevity drugs.” Dr. Ehrenzweig reflects on his shift from a strictly pharmaceutical mindset, describing how client feedback opened his eyes to alternative options and why he was intrigued to join this groundbreaking study. (02:46)Rethinking Canine Cognitive Decline – Dr. Ehrenzweig explains why a CCD diagnosis shouldn't be seen as “the end” for senior dogs, noting that it develops gradually and shares many similarities with human dementia and Alzheimer's. He describes the challenge of studying such a complex condition and the promise of finding better options beyond pharmaceuticals. Dr. Joel expresses hope that demonstrating improvement in dogs could pave the way for better, more natural options for humans facing cognitive decline in the future. (08:10)The Power of Whole-Plant Medicine & Synergy – Angela shares why her mission is to create pure, whole-plant and mushroom formulas rather than isolated compounds, emphasizing that nature's ingredients work best together. Combining adaptogens like Lion's Mane, Reishi, Cordyceps, Ashwagandha, and Bacopa Monnieri creates a synergistic effect—targeting multiple aspects of cognitive decline and delivering the results seen in the Senior Dog Study. (11:55)Measuring the Impact of Mushrooms & Adaptogens on CCD – Carter explains how the synergistic blend of Lion's Mane, Reishi, Cordyceps, Ashwagandha, and Bacopa Monnieri for dogs was designed to address multiple aspects of cognitive decline, from calming the nervous system to supporting neuroprotection and brain oxygenation. To capture these effects, the team used detailed questionnaires and scoring systems to track behaviors like nighttime waking, disorientation, and social engagement—finding that while every dog's response is different, the combination consistently improved quality of life across a wide range of cases.(14:44)Recognizing the First Signs of CCD – Dr. Joel explains that one of the earliest and most telling signs of canine cognitive decline is a shift in sleep patterns—dogs sleeping more during the day, then pacing or appearing restless at night. With wearable collars, pet parents, and researchers, can now track movement and sleep 24/7, giving an objective view of these changes. (20:01)Real-Life Transformations from Mushrooms & Adaptogens – Angela shares moving stories of senior dogs who were scheduled for euthanasia but experienced dramatic turnarounds after starting on these mushrooms & adaptogens—regaining mobility, focus, and connection with their families in just days. Dr. Joel, a seasoned veterinary researcher with over 15 years of experience, admits he had never seen natural ingredients work this quickly and effectively, reinforcing just how extraordinary these study results have been. (26:22)Beyond Anecdotes, Real Evidence from the Senior Dog Study – Carter and Dr. Joel emphasize that the Senior Dog Study is more than just testimonials. By combining real-time collar data that tracks sleep, wake cycles, and activity with caregiver questionnaires and even blood biomarkers like BDNF and CRP, they've created an objective, data-backed picture of how dogs are responding. Dr. Joel notes that even when improvements vary, simply slowing decline can be a meaningful win for families — and in many cases, the results are dramatic, with dogs showing better engagement, calmer behavior, and restored quality of life. (32:42)Episode Resources:The Study: Prospective Evaluation of a Mushroom Derived Nutraceutical in Dogs with Cognitive DeclineLearn more about the Senior Dog StudyWant to be a part of the Senior Dog Study? More on Mushrooms & Adaptogens for Canine Cognitive DysfunctionVeterinary Health Research CentersDownload Angela's Resources at AngelaArdolino.com/podcast-downloadsHave a question about your pet that you want answered on the podcast? Email us at Carter@yournaturaldog.com Visit Angela Ardolino's website for more holistic pet health education: www.AngelaArdolino.comFollow Your Natural Dog on Facebook and Instagram and if you want to see what Angela is up to, follow her on Facebook or join our CBD & Holistic Pet Advice Facebook Group.
An independent, international commission attached to the UN’s Human Rights Council released its report this week, accusing Israel of an ongoing genocide against Palestinians in Gaza. The commission said statements made by Israeli authorities are “direct evidence of genocidal intent.” Nick Schifrin has two views on the report from Craig Mokhabir and Dr. Eran Shamir-Borer. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy
The Evidence Based Chiropractor- Chiropractic Marketing and Research
A new study shows that more degenerative changes on cervical MRIs actually mean less severe headaches in patients with neck pain. So, if you or your patients are stressing over how bad their imaging looks, it's time to rethink that. The big takeaway? Imaging findings don't dictate the future—holistic care, communication, and proactive strategies make the real difference.Episode Notes: Association between cervical MRI findings and patient-reported severity of headache in patients with persistent neck painLeander Tables- Save $1,000 on the Series 950 Table using the code EBC2025 — their most advanced flexion-distraction tablePatient Pilot by The Smart Chiropractor is the fastest, easiest to generate weekly patient reactivations on autopilot…without spending any money on advertising. Click here to schedule a call with our team.Our members use research to GROW their practice. Are you interested in increasing your referrals? Discover the best chiropractic marketing you aren't currently using right here!
This week, Dr. Joel Kahn dives into surprising results from recent medical research. The most eye-opening? Women recovering from a heart attack with relatively preserved heart function were found to have higher mortality risk when discharged on beta-blockers — a finding that challenges 40 years of clinical practice. Dr. Kahn urges listeners to discuss these results with their own healthcare teams. Other unexpected studies are highlighted too, including new insights on taurine, spermidine, meal timing, ketogenic diets, aspirin therapy, and even sugar substitutes. Special thanks to igennus.com — use discount code DrKahn for savings.
Come on dawg!You can find every episode of this show on Apple Podcasts, Spotify or YouTube. Prime Members can listen ad-free on Amazon Music. For more, visit barstool.link/barstoolyak
Fourteen of the most unexpected and counterintuitive science findings. Learn about your ad choices: dovetail.prx.org/ad-choices
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