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On this Friday edition of 2 Pros & A Cup Of Joe, Jonas Knox, Brady Quinn, & LaVar Arrington recap the Bills beating the Lions on Thursday Night Football at Highmark stadium. Plus, the guys discuss the NCAA Oversight Committee ruling on the Michigan vs Western Michigan game, we have North Carolina edition of ICYMI, and more!!See omnystudio.com/listener for privacy information.

The City of Seattle is holding its inaugural Indigenous Civic Engagement Day for urban Natives Friday. As Brian Bull of Underscore Native News reports, the goal is to help the city's Native population connect with officials, services, and funding opportunities. Since 2023, Seattle has held a bi-annual Tribal Summit for members of recognized tribes within the state of Washington, but feedback from several attendees said they would appreciate an event for those Natives who are not necessarily from that group, including Native Hawaiian, Alaska Native, and tribes from other parts of the United States. So Kolbi Monasmith (Cherokee), who is with the Indigenous Advisory Council, says all day Friday, Seattle's city hall will be open for those interested in learning more. “Starting on a base level of: How does the City of Seattle work? How do you advocate for policy within that system? How do you advocate within the city budget system? How does that budget system even work? To build up the knowledge and also build those connections.” Tia Yazzie (Diné), who is also with the Indigenous Advisory Council, said Native voices often go unheard within local politics, so organizers wanted a day and space for people to participate, advocate, and learn about the processes within the Seattle system. “But also to have a fun day. We know learning about these things can be very hard and complex, but we want things to be fun for our families and for also the youth to be involved. So that was one of our big goals, was to have the native community, but also youth involved into this whole community event.” To that end, there will be bingo cards, and demonstrations on beading and making lanyards, as well as headshots taken during the event. It is also the five-year anniversary for the nine-member Indigenous Advisory Council. Yazzie says this has encouraged engagement. “Seattle’s unique in that we have a very special urban native environment and community here that wants to engage in these processes more often than not, and then also to create these programs such as the civic engagement day for or make a space for us, and I think that’s one of the reasons why the IAC was created.” Surveys will be sent to attendees of Friday's civic engagement day to see how effective the City of Seattle was at educating and connecting with its urban Natives. (Courtesy College of Menominee Nation) Tribal Colleges and Universities are a valuable resource for both Native and non-Native residents, but a new report finds the institutions are facing a growing funding squeeze, as Judith Ruiz-Branch reports. A new analysis finds TCUs in Wisconsin are producing measurable economic returns while struggling with longstanding funding disparities. Now, one is focusing its efforts on philanthropy to secure a successful future for students. Findings from the Brookings Institution and the American Indian College Fund show federal support for Tribal campuses has fallen more than 7% over the past decade, despite treaty and trust obligations. College of Menominee Nation President Chris Caldwell says despite their economic value and community impact, Tribal institutions have long needed to advocate for equitable funding and resources that mainstream institutions more readily access. “In grant programs, often times we wear a lot of hats here that mainstream institutions don’t have to wear just because of lack of staffing or resources. So being competitive in that context is always a challenge.” The report says every $1.00 invested in TCUs returns $1.60 in tax revenue and public sector savings. A separate economic impact study found CMN generated $16 million for surrounding counties in one year. Caldwell says the college is now increasing its focus on securing philanthropy contributions and demonstrating the impact on students' lives. A graduate of CMN, he says his experience as a student helped put him on the path to becoming its president. “If we were to look around before the college started to today, you would see a big change in how many Tribal members are in high leadership areas, and not just on our reservation, but in surrounding communities.” The report recommends Congress make greater use of mandatory funding when supporting Native communities, suggesting that strategy would help Tribal colleges plan ahead. American Indian College Fund President Cheryl Crazy Bull says investments in Tribal communities are once again becoming an afterthought – and warns proposed cuts could threaten schools just as they’re finding new ways to reach students. “We’re becoming very adept at online education, so the Tribal colleges are able to bring that culturally rich education that Native people want, where they see themselves and they go to school with each other, even online.” Advocates note the federal government also does not provide enough detailed information about how much money is actually reaching Tribal communities. Crazy Bull says they are pushing for improved data access so Native-serving institutions can determine where the biggest unmet needs remain. And on this day in 1790, a presidential proclamation concerning treaty violations against Native nations appeared in a U.S. newspaper. President George Washington responded to violations of treaties between the United States and the Cherokee, Choctaw, and Chickasaw Nations. The proclamation came during the early years of U.S. treaty-making with sovereign Native nations. Get National Native News delivered to your inbox daily. Sign up for our daily newsletter today. Download our NV1 Android or iOs App for breaking news alerts. Check out today’s Native America Calling episode Friday, September 18, 2026 — Native Playlist: Kole Galbraith and Laura Ortman

Help Persecuted Christians TODAY: https://csi-usa.org/quickstart/ Christian Solidarity International On today's Quick Start podcast: NEWS: The Federal Reserve raises interest rates for the first time in three years, approving a quarter-point hike as it tries to push stubborn inflation back toward its 2% target. FOCUS: The American Bible Society's latest State of the Bible report takes a closer look at forgiveness in America and what the findings reveal about faith, relationships and Scripture. MAIN THING: A Maine mother says the courts have taken away her right to take her 13-year-old daughter to church. Emily Bickford speaks with CBN's Charlene Aaron about the nearly two-year battle and why she's continuing to fight. BIBLE VERSE: “If we are faithless, he remains faithful—for he cannot deny himself.” — 2 Timothy 2:13 (ESV) SHOW LINKS Radical Revelations with Raj Nair https://podcasts.apple.com/us/podcast/radical-revelations/id1888511250 Faith in Culture: https://cbn.com/news/faith-culture Heaven Meets Earth PODCAST: https://cbn.com/lp/heaven-meets-earth NEWSMAKERS POD: https://podcasts.apple.com/us/podcast/newsmakers/id1724061454

Face à certaines campagnes de propagande étrangère, les grands chatbots ont fait mieux qu'une simple recherche Google. Mais leur avantage dépend surtout de leur capacité à décider quelles sources méritent d'être crues. NPR et NewsGuard ont testé cet été six assistants connectés à internet : ChatGPT, Gemini, Copilot, Meta AI, Grok et Claude. Ils leur ont soumis trente questions construites à partir de quinze fausses informations diffusées par des acteurs russes, chinois ou iraniens entre décembre 2025 et juillet 2026. La moitié des questions étaient neutres. Les autres contenaient volontairement une prémisse fausse. Sur cet échantillon, les chatbots ont correctement contesté ces récits environ trois fois sur quatre, et ont globalement mieux résisté que les premières pages des moteurs de recherche. Le résultat est intéressant parce que ces assistants utilisent eux-mêmes le web. Leur avantage ne viendrait donc pas seulement de l'accès à davantage d'informations, mais de leur capacité à confronter plusieurs sources et à signaler qu'une question repose sur une affirmation trompeuse.Cela ne les rend pas pour autant fiables par défaut. NPR a constaté que les chatbots citaient aussi des médias contrôlés ou alignés sur des États, à des taux comparables aux moteurs de recherche. Et les résumés générés directement dans la recherche ont été plus irréguliers : Google AI Overview a généralement bien résisté, tandis que les résumés de Bing ont échoué dans la majorité des cas testés. Une étude publiée en juillet dans les Findings of ACL renforce cette prudence. Quinze modèles ont été confrontés à plus de six mille affirmations vérifiées par PolitiFact. Ajouter une recherche web n'améliorait les résultats que modérément. En revanche, fournir directement aux modèles une sélection de fact-checks fiables améliorait très fortement leurs performances.Autre limite : l'environnement linguistique. Une étude publiée dans Nature a montré que des modèles commerciaux répondaient plus favorablement aux institutions politiques chinoises lorsqu'ils étaient interrogés en chinois plutôt qu'en anglais, et que des contenus contrôlés par l'État chinois apparaissaient dans des corpus d'entraînement. Le message est donc moins spectaculaire qu'un duel entre IA et Google : connecter une intelligence artificielle à internet ne suffit pas. Pour distinguer information et propagande, le vrai avantage commence lorsqu'elle sait aussi hiérarchiser la crédibilité de ce qu'elle trouve. Source Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

Autism spectrum disorder (ASD) and other intellectual disabilities have become a hot button topic in both medicine and the news as of late, with recent questions about the multifactorial causes of intellectual disabilities, including genetics. Developmental-Behavioral Pediatrician Dr. Kendall Abbas is joined by Liliana Amirhosseini and Zoe Gunthert, two fourth year medical students, to discuss presentation, diagnosis, and management of Fragile X, the most common inherited cause of intellectual disability. Specifically, they will Explain the genetics and pathophysiology leading to the Fragile X phenotype Discuss the clinic characteristics associated with Fragile X, allowing for prompt evaluation and management of the symptoms Share treatment plans and resources available for those with Fragile X and their families Special thanks to Dr. Rebecca Yang and Dr. Sarah Straka for peer reviewing this episode. Free CME available:  Link for CME Credit References: Bailey DB Jr, Raspa M, Bishop E, Holiday D. No change in the age of diagnosis for fragile X syndrome: Findings from a national parent survey. 2009 Aug;124(2):527-533.  Hunter JE, Berry-Kravis E, Hipp H, et al. FMR1 Disorders. 1998 Jun 16 [Updated 2024 May 16]. In: Adam MP, Feldman J, Mirzaa GM, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2024. Available from: https://www.ncbi.nlm.nih.gov/books/NBK1384/. Mendez A, Mendez M. Fragile X Syndrome: A Review for General Pediatricians. Pediatr Ann. 2024;53(7):e269-e271. doi:10.3928/19382359-20240502-08 Malecki, C., Hambly, B.D., Jeremy, R.W. et al. The RNA-binding fragile-X mental retardation protein and its role beyond the brain. Biophys Rev 12, 903–916 (2020). https://doi.org/10.1007/s12551-020-00730-4.  National Fragile X Foundation. Prevalence. https://fragilex.org/understanding-fragile-x/fragile-x-101/prevalence/.  Sirois CL, Guo Y, Li M, et al. CGG repeats in the human FMR1 gene regulate mRNA localization and cellular stress in developing neurons. Cell Rep. 2024;43(6):114330. doi:10.1016/j.celrep.2024.114330 Spector, Elaine et al. Laboratory testing for fragile X, 2021 revision: a technical standard of the American College of Medical Genetics and Genomics (ACMG). Genetics in Medicine. 2021;23(5): 799 - 812. doi: 1038/s41436-021-01115-y . 

Fox & Friends First co-anchor Todd Piro joins Marc Cox to discuss global competition surrounding artificial intelligence, evaluates public concerns regarding data center construction, and considers federal regulation policies Fox News. Piro details national security perspectives on AI development, comparing domestic policy constraints with international advancement strategies. The segment concludes with lighthearted banter on paleontology discoveries in North Dakota, NFL quarterback performances, and sports commentary. LISTEN TO 97.1 FM TALK LIVE IN ST LOUIS OR STREAM WORLDWIDE AT 971TALK.COM #971FMTalk #StLouis #STLNews #ToddPiro #AIRegulation #DataCenters

A movie about a songwriter who is too shy to sing, solved by putting her on a bar in wet jeans. Violet Sanford flees New Jersey for Manhattan with a demo tape and roughly nine dollars, gets robbed, gets hired at a saloon whose entire business model is "hydrate the patrons against their will," and discovers that the cure for stage fright is a crowd of drunk men chanting. Meanwhile her father drives down from the Garden State to yell about it, and Adam Garcia keeps showing up like a Australian golden retriever who learned to make omelets. Bruckheimer looked at Flashdance, said "what if less plot and more hose," and cashed a check. We're here for the fire code violations, the LeAnn Rimes of it all, and the moment John Goodman quietly outacts the entire soundtrack. Also: nobody in this bar is ever served a drink. We counted. Can you fight the moonlight? Findings inside. How will Coyote Ugly hold up? Directed by David McNally Starring: Piper Perabo, Adam Garcia, John Goodman, Maria Bello, Izabella Miko, Tyra Banks, Bridget Moynahan, Melanie Lynskey

What does it take to crack the code of protein production and why do some proteins stubbornly refuse to cooperate, despite the best efforts of scientists and engineers? Biotech's ambitions are often limited not by vision, but by the real-world bottlenecks of host cell lines and the unpredictability of post-translational modifications.Nathan Lewis, GRA Eminent Scholar at the Center for Molecular Medicine, Complex Carbohydrate Research Center, and Department of Biochemistry and Molecular Biology at the University of Georgia, has made a career out of asking impossible questions about glycosylation, cell line selection, and the hidden machinery at work inside every productive cell. He's moved beyond academic curiosity—translating discoveries into applications and even launching a company, Augment Biologics, that's taking glycoengineering from theory to practice.Topics discussed:A proximity proteomics approach to identify supporting machinery for challenging-to-express proteins like rituximab (02:36)Findings from expressing the full human secretome in CHO cells, and the correlation between host cell gene expression and protein productivity (05:00)Clarifying when host cell characteristics matter more than the protein construct itself (05:46)Emerging evidence that protein sequence and structure influence glycosylation patterns (contrary to previous dogma) (06:49)Engineering point mutations to precisely tune glycan features for improved therapeutic efficacy (09:25)The vision and activities of Augment Biologics in custom glycosylation control for drug discovery (10:32)The importance and barriers to open data sharing in bioprocessing, and thoughts on overcoming them (11:11)The shifting landscape as technology advances and the need for high-quality, annotated data (13:54)If this got you thinking about the data already sitting in your freezer, and what it would take to actually use it, start here. These four conversations dig into AI-ready data, actionable omics, hybrid-model digital twins, and the cell-engineering biology underneath it all.Episodes 263 - 264: Why AI and Automation Tools Won't Deliver Until Your Lab's Data Is Connected with David HardyEpisodes 173 - 174: Mastering Hybrid Model Digital Twins: From Lab Scale to Commercial Bioprocessing with Krist GernaeyEpisodes 169 - 170: Why Your DNA Is a Terrible Disease Predictor (And How Multi-Omics Changes Everything) with Mo JainEpisodes 77 - 78: Cell Factories Explained: How Synthetic Biology and AI Revolutionize Protein Production with Mauro TorresIf you'd rather follow the glycosylation thread, check Episodes 69 - 70: Glycoanalytics Explained with Róisín O'FlahertyConnect with Nathan Lewis:Website: www.lewislab.uga.edu LinkedIn: www.linkedin.com/in/nathanelewisFree 5-day email course, The CMC Failure Chain: the five recurring CMC mistakes that put your promising program at risk → Get it hereSupport the show

A movie about a songwriter who is too shy to sing, solved by putting her on a bar in wet jeans. Violet Sanford flees New Jersey for Manhattan with a demo tape and roughly nine dollars, gets robbed, gets hired at a saloon whose entire business model is "hydrate the patrons against their will," and discovers that the cure for stage fright is a crowd of drunk men chanting. Meanwhile her father drives down from the Garden State to yell about it, and Adam Garcia keeps showing up like a Australian golden retriever who learned to make omelets. Bruckheimer looked at Flashdance, said "what if less plot and more hose," and cashed a check. We're here for the fire code violations, the LeAnn Rimes of it all, and the moment John Goodman quietly outacts the entire soundtrack. Also: nobody in this bar is ever served a drink. We counted. Can you fight the moonlight? Findings inside. How will Coyote Ugly hold up? Directed by David McNally Starring: Piper Perabo, Adam Garcia, John Goodman, Maria Bello, Izabella Miko, Tyra Banks, Bridget Moynahan, Melanie Lynskey

Private Equity in Primary Care: Just Another Inflationary Business Model? What Does the Data Actually Show, With Yashaswini Singh, PhD (EP528) Private equity has been buying up primary care practices for years, promising the capital that chronically underfunded clinicians badly need. But does the money actually make care better? Yashaswini Singh, PhD, MPA, the Thomas J. and Alice M. Tisch Assistant Professor of Health Services, Policy, and Practice at Brown University, has spent years studying that question — and her newest research, published in Health Affairs and JAMA Health Forum, finds PE-affiliated primary care physicians negotiate prices 8% to 10% higher than independent doctors, while patient outcomes barely budge. WHAT YOU'LL LEARN ✅ Why negotiated prices for PE-affiliated primary care physicians run 8% to 10% higher than independent doctors — and why hospital-affiliated physicians still command the highest prices of all ✅ How a national study of roughly 200 PE-acquired primary care practices found a 20% increase in preventive services, including the Medicare Annual Wellness Visit, with no evidence of low-value care ✅ Why "cognitive atrophy" — deskilling from rigid, box-checking visits — isn't inevitable under PE ownership, but why the "best case scenario" often isn't what's actually happening ✅ How opaque common ownership — the same investors owning primary care, GI, orthopedic, and oncology practices — can create hidden referral incentives current data can't detect ✅ Why site-of-care payment arbitrage — a hospital-owned MRI can cost double or triple an independent one — drives referral-machine incentives regardless of who owns the practice ✅ Why PE's promise to reduce fragmentation through consolidation has instead produced physician turnover that undermines the patient-doctor relationship WHY THIS MATTERS Primary care clinicians are chronically underpaid, and private equity promises the capital to fix that. But Dr. Singh's research shows a real tradeoff: costs rise 8% to 10% while quality barely moves. Whether professional capital builds sustainable, whole-person care or becomes, as Stacey puts it, corporate arbitrage in a different Halloween costume depends on realigning payment incentives around outcomes rather than throughput — something no ownership model, PE included, is yet built to do. MENTIONED IN THIS EPISODE EP519 with Lisa Rosenbaum, MD: Apple Podcasts | Spotify | Other Apps LinkedIn Post by Yashaswini Singh, PhD EP474 with Yashaswini Singh, PhD: Apple Podcasts | Spotify | Other Apps Study: "Private Equity Acquisitions in Primary Care" (Health Affairs) Study: "Private Equity Acquisition in Primary Care and Avoidable Hospitalizations" (JAMA Health Forum) LinkedIn Comment by Andrea DeSantis, DO, FAAFP EP521 with Andrew Tsang: Apple Podcasts | Spotify | Other Apps EP523 with Suhas Gondi, MD, MBA: Apple Podcasts | Spotify | Other Apps === LINKS ===

Dr. Ashwin Parihar speaks with Dr. Olayinka A. Abiodun-Ojo and Dr. David M. Schuster about findings from the EMPIRE 2 trial, exploring how fluciclovine PET and PSMA PET influence salvage radiotherapy planning for men with recurrent prostate cancer after prostatectomy. The discussion examines the strengths and limitations of each tracer, the importance of prostate bed detection, and where fluciclovine may still have a role in the evolving era of PSMA-targeted imaging. 18F-Fluciclovine or 68Ga-PSMA-11 PET/CT–guided SalvageRadiotherapy Changes in Postprostatectomy BiochemicalRecurrence: Secondary Analysis of the EMPIRE-2 Trial. Abiodun-Ojo and Jani et al. Radiology 2026; 319(3):e251874. 

Hosts: Ed Jones (Owner – Nutrition World) & Clint Powell A variety of topics all related to living a healthy life Presented by: Nutrition World www.nutritionw.com Broadcasting from the Nooga Dentistry Studio www.noogadentistry.com Production of: Whitfield Media Group www.vitalhealthradio.com Title: Rethinking Bone Health: Osteoporosis, Exercise and Essential Nutrients [0:04:00] Clint's New Book & Ed's eBooks/Publishing Plans Clint introduces his new book: Title: The Room with No Doors: How We Trap Ourselves Defending Our Excuses. Format: Paperback + Kindle, includes some work sections at the back. Focuses on seven common excuses we use to avoid trying solutions, trapping ourselves. Available on Amazon; early sales have pushed it into top rankings in certain Kindle and paperback categories. Another book is already written and queued for release around late October / early November. Ed discusses his own Holistic Navigator eBooks: Topics: staying healthy, getting healthy, sleep, oral hygiene, oxalates, AI for fat loss, the “Core Four” foundational supplements, etc. Currently on theholisticnavigator.com; Ed plans to follow Clint's lead and bring them to Amazon/Kindle. [0:06:37[ Labor Day, Nutrition World Shopify Rollout Ed shares that this Labor Day marks a huge milestone for Nutrition World: Full migration to a Shopify-based system for online business. Compared to the massive move years ago from Brainerd Village to Lee Highway, this is framed as the second biggest event in decades. Acknowledges it's been extremely expensive and complex, but promises major improvements in convenience and efficiency for customers. Announcement: Lisa Bloom (lactation expert from Knoxville) has joined Nutrition World: Deep experience helping mothers through lactation challenges. Notes that without support, ~50% of mothers quit breastfeeding due to difficulty. Lisa will offer consultations at Be Well Labs (near Nutrition World), bookable via NutritionW.com / BeginWithLabs.com. [0:09:50] “Teacher of the Week” & Chronic Pain as a Brain Response Ed introduces a recurring concept: “Teacher of the Week” – highlighting sources of health wisdom. This week's teacher: “Pain Free You” (YouTube channel). Ed has personally counseled with the creator. Core idea: a large portion of chronic pain is generated by the brain as a protective distraction from emotional pain or unresolved inner issues. Featured video: “You Are Not Sick, You Are Scared.” Distinguishes between: Structural pain (like Clint's hip, back, knee issues – “flat tires”) where anatomy is clearly damaged. Chronic, shifting, unexplained pain where the nervous system and fear may be the primary drivers. [0:13:33] Upcoming Events September 16 – Talk at Nutrition World by Katie Poole on optimizing fertility. October 24 – Large-scale Health Fair [0:17:44] Segment with Dr. Curt Dearing: Osteoporosis, Osteopenia & Bone Health Clint re‑introduces the show and brings in Dr. Curt Dearing, clinical pharmacist (~35 years' experience). Curt previews the segment (osteoporosis/osteopenia) and contrasts: Conventional approach: heavy on calcium supplements and prescription drugs (e.g., bisphosphonates like Fosamax). Holistic approach: broader lifestyle interventions – targeted nutrients (vitamin D, vitamin K2, vitamin C, boron, strontium), exercise, and fall prevention. Key critiques of conventional diagnosis: The T‑score system compares bone density to that of a young adult, effectively turning normal age-related bone loss into a “disease.” Similar over‑medicalization compared to blood pressure and cholesterol, which also naturally shift with age. Concerns about bisphosphonates (e.g., Fosamax): Originated from chemicals used to soften irrigation water. Improve bone density numbers on scans but can create denser yet more brittle bones. Side effects: Esophageal ulcerations if not taken properly (must sit upright with full glass of water). Rare but devastating jawbone degeneration (osteonecrosis of the jaw). Long‑term use may increase hip fractures; minimal benefit in men and women > 80. Real fracture risk driver: falls, not just bone density. Most fractures in the elderly occur in people without osteoporosis. Priorities: Muscle mass and strength. Cognitive function to reduce fall risk. Lifestyle foundation for bone health: Exercise is primary: Weight‑bearing and high‑intensity training. Weighted vest especially beneficial for lighter women (they lack constant load on bones). General recommendation: 30–60 minutes, 3–4 times per week, with heart rate around 120 minus age for cardio work (not necessarily with the vest). Diet and acid load: Excess acid‑forming foods (grains, dairy, meat, coffee, sugar) can create acidosis, prompting the body to pull minerals (like calcium) from bone to buffer pH. Malabsorption issues (celiac, GI problems, proton pump inhibitors like Nexium) reduce absorption of calcium, magnesium, etc. Supplement strategy: Calcium: important but typical 1,200 mg/day is likely too high; better range 400–1,000 mg, depending on diet. Excess isolated calcium can increase fracture risk. Vitamin D + Vitamin K2 (MK‑7 form): K2 directs calcium out of arteries and into bones. D and K work synergistically; many combo formulas under‑dose D and K, so often need separate higher‑dose D/K. Optimal vitamin D blood levels: generally 60–70 ng/mL; anything under 40 is likely deficient. Toxicity is rare; usually only with abuse of high‑dose (50,000 IU daily instead of weekly). Other helpful nutrients: Vitamin C, boron, strontium. Strontium should be taken separate from calcium/bone formulas. Vitamin K and blood thinners: Vitamin K is crucial not only for clotting but also for bone and cardiovascular health. Only warfarin (Coumadin) users must tightly regulate vitamin K. Newer anticoagulants (Eliquis, Xarelto) do not require vitamin K restriction. [0:39:03] Segment 3: Labs, Spike Protein, Long COVID & Upcoming “Chicken” Episode Ed shares he is getting blood work at Be Well Labs (BeginWithLabs.com): Specifically testing spike protein levels due to curiosity about long COVID. References a previous guest MD who had repeated COVID infections and very high spike protein levels (~870 vs. normal 30% body fat, exercising less than 3x/week. Caffeine doses tested: 3 mg/kg (roughly 200–210 mg for Ed's weight). 5 mg/kg (~300 mg). 9 mg/kg (~500 mg). Findings: 3–5 mg/kg significantly increased fat oxidation vs. placebo. 9 mg/kg gave no added benefit and led to side effects (nervousness, higher blood pressure). Real‑world translation: About 200–300 mg caffeine pre‑exercise appears ideal for fat‑burning benefits. Examples: Starbucks grande cold brew: ~205 mg. Starbucks grande hot coffee: ~310 mg. Ed plans to use caffeine for life, especially pre‑gym, in this moderate dose range. [0:48:08] Xylitol & Cardiovascular Risk Discussion of new research linking xylitol intake to major adverse cardiovascular events (MACE): Study of ~17,000 people, average age ~61, over 6–30 years. Higher intakes of xylitol were associated with increased risk of cardiac events. Mechanism: around 30 g of xylitol can increase platelet aggregation, thickening the blood and potentially increasing clot risk. Practical implications: Chewing gum with xylitol is likely low risk due to small doses. Biggest concern: 16‑oz canned drinks heavily sweetened with xylitol. Nutrition World will scan store beverages and aim to transition away from xylitol‑sweetened drinks toward stevia‑based options. Brief note: some emerging chatter on stevia and possible neurological effects, but Ed notes that appears tied to genetic vulnerabilities, whereas xylitol issues may be more generalized. [0:50:38] Post‑Stomach Bug Recovery: What to Eat Guidance for recovering from stomach bugs (vomiting/diarrhea): Immediate phase: simple, gentle foods like broth. Special protocol (especially for kids): green bananas + rice. Research suggests green bananas plus rice work significantly better than rice alone for recovery. Crucial step: reintroduce protein as soon as symptoms improve. Protein speeds recovery and supports healing. Early on, protein may be easier to drink (e.g., smoothies, shakes) than to eat as solids. [0:56:48] Fauci Advisor Indictment, EMFs/5G/6G & Final Thoughts Ed mentions news that David Morens, MD (former senior advisor to Anthony Fauci at NIAID) pleaded guilty to conspiracy to defraud the U.S. and could face up to 5 years. Framed as part of a broader process of information “coming out” about the COVID era. EMFs, 5G, and coming 6G: Ed reiterates concerns about EMF/5G exposure and its effects on neurochemistry. Notes that 6G is expected around 2030, raising new concerns. Mentions his use of Blue Shield EMF mitigation devices in the bedroom and for family. Clarifies these do not “block” EMFs (only physical shielding like silver fabric can) but are intended to help the body adapt to EMF stress. Amish & vaccine mandates (brief mention): Amish communities in New York reportedly threatened mass exodus over pressure around vaccines, raising questions about medical mandates and rights. Ed closes with a quality‑of‑life perspective: His goal is not necessarily to live more days, but to live higher‑quality days. Recaps that he's lived “80 mph most of the time” and wants to maintain quality through proactive health choices. The post Radio Show / Podcast – September 6, 2026 first appeared on Vital Health Radio.

Todd Curtis and John Goglia take a closer look at the crash of a Fairchild SA227-TT in Blountville, Tennessee that killed NASCAR champion Alan Kulwicki and others. They bring to light why this plane crash wasn't simply a story about bad weather.On April 1, 1993, Kulwicki was flying to Tennessee to compete at Bristol Motor Speedway when the aircraft carrying him crashed during a night instrument approach. Kulwicki, the 1992 Winston Cup Champion, two other passengers, and the pilot were killed.An air traffic controller watched the aircraft descend in a spiraling descent shortly before it crashed short of the runway. Investigators determined that the pilot had not followed the manufacturer's recommended procedures for operating in icing conditions.Todd and John examine the chain of decisions and conditions that led to the loss of control. They document the weather conditions surrounding the flight, including the forecast for icing at 7,500 feet while the aircraft cruised at 7,000 feet. John discusses research from the 1990s demonstrating just how rapidly ice can accumulate on an aircraft.They also explore a lesson that remains highly relevant to pilots today: weather information is never truly "live." Even modern in-flight weather systems have delays.This tragic crash offers important lessons for pilots, aviation professionals. Anyone interested in understanding how seemingly manageable conditions can combine to create a deadly accident needs to watch this episode. Don't miss what's to come from the Flight Safety Detectives - subscribe to the Flight Safety Detectives YouTube channel, listen at your favorite podcast service and visit the Flight Safety Detectives website. Want to go deeper with the Flight Safety Detectives? Join our YouTube Membership program for exclusive perks like members-only live streams and Q&As and early access to episodes. Your membership support directly helps John, Greg and Todd to deliver expert insights into aviation safety.Interested in partnering with us? Sponsorship opportunities are available—brand mentions, episode integrations, and dedicated segments are just a few of the options. Flight Safety Detectives offers a direct connection with an engaged audience passionate about aviation and safety. Reach out to fsdsponsors@gmail.com. Music: “Inspirational Sports” license ASLC-22B89B29-052322DDB8 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Jason Smith and Mike Harmon were locked, loaded, and ready to entertain the masses on a busy night in sports. Jason tells you why Rutgers Football is the reason you don't bet Week 1 of college football. Any chance Dabo Swinney and Clemson wake up tomorrow refusing to play LSU? And the guys reacted to The Athletic releasing their Dianna Russini/Mike Vrabel investigation findings!See omnystudio.com/listener for privacy information.

Carl and Mike are joined by Steve Koonin as they discuss the latest on the Atlanta Hawks and the NBA.

Show Notes: Chaudhry, S., & Kulkarni, C. (2021). Design patterns of investing apps and their effects on investing behaviors. In Proceedings of the 2021 ACM Designing Interactive Systems Conference (DIS '21) (pp. 777–788). https://doi.org/10.1145/3461778.3462008 Dickinson, D. (2026). Dark patterns and consumer protection law for app makers. Consumer Law Review. https://www.researchgate.net/publication/400702824_Dark_Patterns_and_Consumer_Protection_Law_for_App_Makers Farronato, C., Fong, J., & Larkin, I. (2025). Designing consent: Choice architecture and consumer welfare. Management Science. https://doi.org/10.1145/3736252.3742627 International Organization of Securities Commissions. (2023). Online choice architecture: How digital design is used to influence investors (IOSCO PD794). https://www.iosco.org/news/pdf/IOSCONEWS688.pdf Kahneman, D. (2011). Thinking, fast and slow. Farrar, Straus and Giroux. Lai, L. (2024). Playful finance: Gamification and intermediation in fintech. Journal of Financial Regulation, 10(1), 1–35. https://doi.org/10.1016/j.jfr.2023.100174 Lusardi, A., & Mitchell, O. S. (2014). The economic importance of financial literacy: Theory and evidence. Journal of Economic Literature, 52(1), 5–44. https://doi.org/10.1257/jel.52.1.5 Madrian, B. C., & Shea, D. F. (2001). The power of suggestion: Inertia in 401(k) participation and savings behavior. Quarterly Journal of Economics, 116(4), 1149–1187. https://doi.org/10.1162/003355301753265543 Mathur, A., Mayer, J., & Kshirsagar, M. (2019). Dark patterns at scale: Findings from a crawl of 11K shopping websites. Proceedings of the ACM on Human-Computer Interaction, 3(CSCW), 1–32. https://doi.org/10.1145/3359183 Rakovic, M., & Inal, Y. (2023). Dark finance: Exploring deceptive design in investment apps. International Journal of Human-Computer Studies, 170, Article 102944. https://doi.org/10.1016/j.ijhcs.2022.102944 UK Financial Conduct Authority. (2024, July). Review of online choice architecture and vulnerability [Regulatory discussion paper]. https://www.citizensadvice.org.uk/policy/publications/review-of-online-choice-architecture-and-vulnerability/ Savitha, B., & Hawaldar, I. T. (2022). What motivates individuals to use FinTech budgeting applications? Evidence from India during the COVID-19 pandemic. Cogent Economics & Finance, 10(1). https://doi.org/10.1080/23322039.2022.2127482 Thaler, R. H. (2015). Misbehaving: The making of behavioral economics. W. W. Norton & Company. Thaler, R. H., & Sunstein, C. R. (2008). Nudge: Improving decisions about health, wealth, and happiness. Yale University Press. Veigas, P. (2023). A comprehensive analysis of the user experience in digital platforms concerning the practice of nudging user behaviour. Journal of Behavioral and Experimental Economics, 104, Article 101986. https://doi.org/10.1016/j.socec.2023.101986 Report a Dark Pattern with the FDIC: https://reportfraud.ftc.gov/

In this podcast episode, Hope S. Rugo, MD, FASCO, and Nerea Lopetegui-Lia, MD, discuss practice-informing data presented at ASCO 2026 for patients with early-stage hormone receptor (HR)–positive/HER2-negative breast cancer, including:Findings from the OPTIMA trial evaluating Prosigna gene expression testing to guide adjuvant chemotherapy decisions in patients with high-risk HR-positive/HER2-negative early breast cancerThe importance of ovarian function suppression plus endocrine therapy when considering chemotherapy-sparing strategies in premenopausal patientsResults from the NATALEE PAM50 biomarker analysis, showing ribociclib benefit across intrinsic subtypes with no significant treatment-by-subtype interactionPresenters:Hope S. Rugo, MD, FASCODirector, Women's Cancer ProgramDivision Chief, Breast Medical OncologyProfessor, Department of Medical Oncology & Therapeutics ResearchCity of Hope Comprehensive Cancer CenterProfessor Emeritus and Emeritus Winterhof Family Distinguished Professor of Breast OncologyUniversity of California, San FranciscoSan Francisco, CaliforniaNerea Lopetegui-Lia, MDAssistant ProfessorDivision of Medical Oncology, Breast SectionDepartment of Internal MedicineThe Ohio State UniversityColumbus, OhioGet access to all of our new podcasts by subscribing to the Decera Clinical Education [Oncology] Podcast on Apple Podcasts, YouTube Music, or Spotify.Link to full program: https://bit.ly/4x4u5AT Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

RHR Interviews Dr. Richard Ostfeld, a Cary Institute disease ecologist who co-directs the tick-monitoring program and is a coauthor of this paper revealing some surprising Lyme Disease findings. For more than 35 years, researchers at the Cary Institute of Ecosystem... Read More ›

Findings from Box's State of AI in the Enterprise survey show 83% of enterprises are now running agents in some capacity.These bots are enabling teams to drive productivity and efficiency, but as with any new technology, smooth integration can be a challenge - and security risk.Recent agent-related incidents in the tech industry have sparked concerns about long-term security implications.In this week's episode of the ITPro Podcast, Ross Kelly and Bobby Hellard speak with Box CISO Heather Ceylan to discuss how Box is using agents internally, and how enterprises can adopt the technology in a safe and secure manner.Highlights“I think for security teams, we can finally, you know, start having the capacity to outpace these attackers. So we've got five core areas of investment for agents for our security team in particular that we've invested in over probably the last year, and we're starting to measure ROI on those right now.“So the first one is in the SOC. I think that's probably the most obvious choice where we've got a lot of operational work. We see the same kinds of incidents. We're automating the triage, we're automating the enrichment, the log correlation, things like that that take a lot of human effort.“But there's still human judgment in the end in terms of what gets escalated to be an incident and what doesn't.”“We're not going to be able to move fast enough. So, we have agents kind of built throughout our software development process, doing those security design and architecture reviews, and if you think about it, it's way more powerful than a human can be because those agents don't just necessarily call out design flaws; they can enforce fixes for those flaws.”“Things are changing quickly. Sometimes it feels like you take two steps forward and then you read something in the news and you're like, oh my gosh, we need to rethink everything.“So I think a lot of security teams are really feeling that now and getting a little bit of fatigue from that.““One of the things that we're trying to carry across all of these that I wasn't really thinking about a year ago, but I'm thinking a lot about now is having that multi-model approach.“We're not in a place where most of the work we do, we can't be reliant on a single model. If you look at vulnerability discovery, we're moving away from being tied to any one specific vendor or any one specific model because you're going to get better results when you take a multi-model approach.”LinksAI is getting better at security – and it's doing it faster than expectedTop security teams use AI agents, says Hack The BoxAI is changing team structures in cybersecurity and creating new roles – here are the jobs in hot demandCan AI fight AI? Where the security gap still exists in cybersecurity, and how MSPs can help

"I LOVE THIS COMPANY!!!!!!!!!!!!!!!!!!!!" Well, the day has finally come. Adam Silver and the NBA levied their punishment against Steve Ballmer, Gillian Zucker, Lawrence Frank, Kawhi Leonard, and the Los Angeles Clippers, and we have the man who started it all, Pablo Torre, on the show to share ALL the details. How did we end up here? What's the most interesting piece of the investigation's findings? Does Pablo know how to pronounce Gillian Zucker's name? Today's cast: Dan, Your ol' pal Dave Dameshek, Roy, Chris, Jeremy, Tony, and Zaslow. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Jones & Keefe | Thursday 9/3/2026

Today on Jones & Keefe: Is it time to start panicking about Red Sox pitching; Roman Anthony is officially back; What's going on with Willson Contreras; Will Trevor Story be a factor in this pennant race; The importance of the Patriots getting off to a hot start; Do the Pats have a chance in Seattle; Rob Bradford joins live to remind you to always pay attention to the lights on your car dashboard; Adam Silver brought the hammer down on Steve Ballmer and the LA Clippers; Jones & Keefe break down their fantasy strategies; Can the Red Sox be fixed; Roman Anthony's looking good at least; Keefer Madness: Otter Insanity; Is Drake Maye up for this challenge; Mike Vrabel's latest comments; Grab Bag; Clip Du Jour

This hour: Is Drake Maye up for this challenge; Mike Vrabel's latest comments; Grab Bag; Clip Du Jour

Top 3 Stories of the Day: The SEC is SUING Lane Kiffin & LSU, The Athletic Published its findings on Dianna Russini, A look at tonight's College Football Landscape

This Day in Maine for Wednesday, September 2, 2026.

Dr. Heon-Jeong Lee (Korea University, Seoul) joins AJP Audio to discuss an app-based intervention designed to help individuals with mood disorders regulate their circadian rhythms to prevent recurrence of mood episodes.  Afterwards, Dr. Ned Kalin will join us again to discuss the rest of the September issue of the Journal, which takes a close look at clinical treatment. 00:44     Findings 01:42     How the app works 03:05     Differences between the app and traditional lifestyle advice 04:14     Ethics surrounding shame treatment arms 05:43     Broader applicability of the intervention 06:50     Limitations 08:19     Immediate clinical implications 09:33     Further research 10:08     Kalin interview 10:27     Yeom et al. 16:02     Schacht et al. 20:31     Khosravani et al. 24:52     Peterson et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org

Sandy Wright, Head of Devices at Scarlet, the first notified body built specifically around software as a medical device. A former doctor who moved from clinical practice into digital health. Sandy now sits on the assessment side of the table, reviewing the very submissions most manufacturers dread putting together.In this episode, we start with the question that trips up so many companies. What actually turns a piece of software into a medical device and why is the wellness boundary still so blurry that entire businesses are straddling the divide without realising it. Sandy shares some of the more unusual examples out there, including AI ambient scribes and augmented reality tools that let surgeons revisit patient scans mid-operation.We then go inside Scarlet itself. Sandy explains why they see themselves as a technology company first and a notified body second, how a combination of expertise, redesigned process and their own internal tooling means customers are not sitting at the back of a queue for months and what genuinely drives faster conformity assessment.The most valuable part for anyone in this space is Sandy's breakdown of where nonconformities actually come from. Clinical evaluation, post-market clinical follow up treated as an afterthought, incomplete software requirements and risk analyses that are too narrow. We also cover the EU AI Act and how it may or may not intersect with MDR, what makes a genuinely good PCCP and Sandy's parting advice on the underrated power of narrative in a regulatory submission.Timestamps[00:01:00] What Actually Turns Software Into a Medical Device[00:03:39] AI Scribes and AR Headsets: SaMD You Might Not Expect[00:06:10] Why Scarlet Sees Itself as a Technology Company First[00:08:43] How Scarlet Cut Assessment Timelines Without Cutting Corners[00:12:12] Clinical Evaluation: The Most Common Source of Findings[00:13:18] Why Post-Market Clinical Follow Up Is Treated as an Afterthought[00:16:20] Risk Management and Why a Narrow Lens Causes Problems[00:16:55] The EU AI Act and How It May Intersect With MDR[00:19:56] From Foundation Doctor to Babylon Health and Beyond[00:22:42] What Separates a Good PCCP From a Box-Ticking OneConnect with Sandy - https://www.linkedin.com/in/wrightsandy/Learn more about Scarlet - https://www.scarlet.cc/Get in touch with Karandeep Badwal - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/karandeepbadwal/ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow Karandeep on YouTube - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/@KarandeepBadwal⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Medical device training courses delivered by Karandeep through Bywater - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.bywater.co.uk/

Understanding the decision of parents to opt-out of medically actionable secondary findings offered through genome sequencing   Guest Bios: Robin Hayeems is a Senior Scientist in Child Health Evaluative Sciences (CHES) at The Hospital for Sick Children (SickKids) and an Associate Professor in the Institute of Health Policy, Management and Evaluation (IHPME) at the University of Toronto. She is trained in genetic counselling public health and bioethics, health policy research, and health services research.. Her research focuses on the development, implementation, and evaluation of genomic screening and diagnostic tools for the maternal-child health context. As a member of several provincial advisory committees, her work informs and is informed by policy development in this area.   Abby Hansen is a Master of Science in Genetic Counselling student at the University of British Columbia and a Clinical Research Project Assistant at The Hospital for Sick Children (SickKids). Her research focuses on exploring patient experiences with genetic testing and the factors that shape genetic testing-related decision-making. Drawing on both her research experience and clinical training, Abby is passionate about providing compassionate, patient-centred care, and supporting individuals and families in understanding complex genetic information and making informed healthcare decisions.   In this episode we discuss: - Exploring the unexpectedly high opt-out rate for medically actionable secondary findings in Genome-Wide Sequencing Ontario (GSO) and how Canadian guidance surrounding non-diagnostic results differs from U.S. standards. - Unpacking how the emotional workload of managing acute medical crises leads some parents to decline secondary findings to avoid living under a "cloud of worry," balancing proactive healthcare with current family peace of mind. - Challenges around pediatric autonomy, parental consent misunderstandings regarding data re-analysis, and the clinical case for flexible, two-step disclosure models. - Educational tools, scripts, and capacity-building strategies designed to improve genomic literacy among non-genetics providers as genome sequencing expands into mainstream care   Resources - Genome Sequencing Ontario URL website   Would you like to nominate a JoGC article to be featured in the show? If so, please fill out this nomination submission form here. Multiple entries are encouraged including articles where you, your colleagues, or your friends are authors.   Stay tuned for the next new episode of DNA Dialogues! In the meantime, listen to all our episodes Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Dialogues”.    For more information about this episode visit dnadialogues.podbean.com, where you can also stream all episodes of the show. Check out the Journal of Genetic Counseling here for articles featured in this episode and others.    Any questions, episode ideas, guest pitches, or comments can be sent into DNADialoguesPodcast@gmail.com.    DNA Dialogues' team includes Jehannine Austin, Naomi Wagner, Khalida Liaquat, Kate Wilson and DNA Today's Kira Dineen. Our logo was designed by Ashlyn Enokian. Our current intern is Vanaja Chavva.

Former Carlton captain Sam Docherty joined Jacqui Felgate to talk about the latest news in the AFL, and the big weekend ahead.See omnystudio.com/listener for privacy information.

New research from the NTA has shown that every one euro invested in active travel this decade generates almost four euro in benefits to society. We get the details from Conor Geraghty is Head of Active Travel with the NTA.

Please email ppls.adhdstudy@ed.ac.uk if you would like to learn more.Why do so many young people with ADHD find it harder to bounce back from difficult emotions — and what can actually help?This episode of the Mind the Kids podcast features Professor Aja Murray, Professor of Developmental Psychology of Mental Health at the University of Edinburgh's School of Philosophy, Psychology and Language Sciences. Aja's research examines mental health across the lifespan, with a particular focus on the links between ADHD symptoms and co-occurring mental health issues such as anxiety and depression, especially during adolescence.Hosted by Mark Tebbs, the conversation explores the Mental Health in the Moment ADHD (MHIM-ADHD) programme of research, funded by the Medical Research Foundation, conducted with colleagues including Dejla Hoxha and Daria Melashenko at the University of Edinburgh and Amanda Russell at Northumbria University, alongside guidance from the project's young person and lived-experience advisory group.The discussion opens by unpacking two key terms: ADHD, characterised by difficulties with attention, hyperactivity and impulsivity and diagnosed in up to around 8% of children and adolescents globally, and emotion dysregulation, the breakdown of the processes people use to identify, manage and respond to their emotions. Aja explains how emotion dysregulation, while not a core symptom of ADHD, is a commonly associated feature that can show up as intense or changeable emotions, emotions that take longer to settle, or emotionally driven behaviour such as lashing out.Drawing on ecological momentary assessment methods that capture emotion regulation as it unfolds in daily life, alongside longitudinal data, Aja shares findings on how emotion dysregulation sits on the pathway between ADHD symptoms and elevated risk of anxiety and depression, and how patterns like rumination are a particularly important feature of this pathway. The conversation also explores rejection sensitivity dysphoria — the tendency to anxiously or angrily anticipate social rejection — a concept gaining significant attention within the ADHD community. The project's lived-experience advisory group specifically recommended including a measure of rejection sensitivity, informed by broader work on co-producing adolescent mental health research with young people (Health Expectations). Findings show rejection sensitivity dysphoria is linked to more negative emotions day to day, but that positive peer interactions can buffer this effect, pointing to peer acceptance as a promising avenue for support.Aja also sets out practical, evidence-based strategies for adolescents with ADHD and the adults who support them, including cognitive reappraisal, techniques for interrupting rumination, acceptance, square breathing, and the "grounding" 5-4-3-2-1 technique. The conversation covers the crucial role of parents and caregivers in modelling emotion regulation, understanding how the ADHD brain processes emotion, and responding supportively rather than dismissively to emotional expression — plus a look at positive emotion regulation, including noticing, savouring and sharing good moments. Aja closes with an update on the team's emerging work on teacher relationships, autistic traits, and a co-produced digital emotion regulation app for adolescents with ADHD.This conversation is essential listening for clinicians, researchers, educators, and parents and caregivers interested in child and adolescent mental health, ADHD, emotion regulation, and rejection sensitivity dysphoria. It offers a clear, hopeful message: emotion regulation is a skill that can be learned, practised, and strengthened over time.Learn more about the MHIM-ADHD study protocol: 'Illuminating the daily life experiences of adolescents with and without ADHD: protocol for an ecological momentary assessment study', Aja Murray, Lydia Speyer, Melissa Thye, et al. BMJ Open, published 29 September 2023. https://doi.org/10.1136/bmjopen-2023-077222Get a free CPD/CME certificate for listening to this podcast by registering for a FREE ACAMH Learn account at https://bit.ly/4fF4BBWDon't miss our webinar on 04/11/26 Led by leading expert Dr. Alessio Bellato 'Assessment Tools and Interventions for Emotion (Dys)Regulation: Practical Approaches'. Emotion regulation is a key skill for well-being, yet individuals, particularly those who are neurodivergent, may experience unique challenges in managing emotions in daily life. This two-part short course provides a practical approach to understanding, assessing, and providing personalised support across diverse populations.Visit https://www.acamh.orgFacebook and LinkedIn search / ACAMHInstagram https://www.instagram.com/assoc.camhBluesky https://bsky.app/profile/acamh.bsky.socialX https://x.com/acamh

In this episode, host Leda McDaniel speaks with Dr. Thomas Ibounig, shoulder and elbow surgeon at Helsinki University Hospital and researcher with the Finnish Centre for Evidence-Based Orthopaedics.Dr. Ibounig discusses his 2026 JAMA study, “Incidental Rotator Cuff Abnormalities on Magnetic Resonance Imaging.” The conversation explores how common rotator cuff abnormalities are on MRI, including in asymptomatic individuals, and what that means for clinicians interpreting imaging findings in patients with shoulder pain.The study used a representative Finnish population sample, bilateral 3 Tesla MRI imaging, shoulder surgeon clinical examination, and extensive questionnaire data to examine the relationship between imaging findings, symptoms, clinical tests, and broader patient factors.Dr. Ibounig explains why MRI findings and isolated clinical tests may not identify the source of pain as reliably as clinicians often assume. He also discusses why terminology matters when explaining imaging to patients, how structural findings can become over-medicalized, and why future research needs to look beyond anatomy toward psychological, occupational, metabolic, and longitudinal contributors to shoulder pain.This episode is especially relevant for orthopedic manual physical therapists, surgeons, sports clinicians, educators, and anyone helping patients make sense of shoulder MRI findings.Link to referenced study: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2844659Key TakeawaysMRI abnormalities are extremely common after age 40.Dr. Ibounig reports that nearly every shoulder over 40 in the study showed some abnormality on MRI.Abnormal does not always mean pathological.Findings such as tendinopathy, partial-thickness tears, and even some full-thickness tears may be part of aging rather than the clear source of symptoms.Symptoms and imaging do not map cleanly.Full-thickness rotator cuff tears were more common in symptomatic shoulders, but many findings were also present in asymptomatic shoulders.Clinical tests may not add as much certainty as clinicians hope.Even a thorough clinical exam did not clearly improve the ability to distinguish symptomatic from asymptomatic rotator cuff findings.Language matters.Telling a patient their shoulder is “torn” or “broken” can create fear, even when the finding may be common for their age.Shoulder pain needs a broader explanatory model.Dr. Ibounig emphasizes that future research should explore pain mechanisms beyond structure, including psychological, metabolic, occupational, and longitudinal factors.Clinical humility is essential.One of the episode's strongest messages is that experience often brings less certainty, not more.

A look at a new report by Common Sense Media on how children are adapting to AI use in the classroom. Also, sitting down with Chase Stokes ahead of the series finale of the popular Netflix show “Outer Banks”. Plus, an edition of Today Bestsellers, with finds that will get you refreshed and ready for fall. And, actor and comedian Will Forte stops by discuss his newest movie “Coyote VS. Acme”.  Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Dr. Hoffman continues his conversation with cardiologist and electrophysiologist Dr. Gregory Marcus, chair of the American Heart Association scientific statement writing group.

Cardiologist and electrophysiologist Dr. Gregory Marcus, chair of the American Heart Association scientific statement writing group, reveals evidence on coffee/caffeine and cardiovascular health. He discusses how earlier assumptions that caffeine triggers arrhythmias are complicated by genetics, individual risk factors, and mostly observational research. Marcus reviews randomized and observational findings: the CRAVE trial showed no increase in premature atrial contractions but more premature ventricular contractions on coffee days; a trial in post-cardioversion patients found less atrial fibrillation with daily coffee. Observational data suggest lower risks of type 2 diabetes, heart attack, stroke, and AFib among coffee drinkers, while heart failure risk may be lower at low intake but higher around 4–5 drinks/day. He cautions against extrapolating benefits to energy drinks, discusses additives like sugar, touches on alcohol, cannabis, Mediterranean/DASH diets, pollution, and evolving AFib treatments, wearables, and pacing/ablation technologies.

What happens before the adjustment can be just as important as what happens on the table. In their 100th epsisode, Dr. Fred and Dr. FJ break down the consultation, not as a sales presentation, but as the foundation for trust, clinical certainty, patient understanding, and better long-term outcomes. They explore how great doctors uncover what's really happening beneath a patient's immediate complaint: previous experiences and objections, limitations in everyday life, the true chronicity of the problem, and the difference between symptoms and dysfunction. Dr. FJ walks through the questions he uses to connect those dots before the Report of Findings, while Dr. Fred emphasizes the importance of gratitude, certainty, knowing your numbers, understanding severity, and giving healing the time and energy it requires. They also tackle an important balance in practice: know your outcomes without becoming consumed by them. Build a great process. Deliver a great consultation. Communicate clearly. Give the best care you can. Build rapport and get results. Because when you become exceptional at delivering what patients actually need, you don't have to spend your energy trying to sell them. What You'll Get From This Episode A clearer framework for conducting a purposeful consultation Questions that help uncover objections, limitations, and chronicity How to connect a patient's symptoms to what they're actually experiencing functionally Why the consultation can make or break the Report of Findings How severity should influence recommendations rather than relying on a one-size-fits-all plan Why clinical certainty and continued training matter How to track practice numbers without becoming emotionally controlled by them A reminder that sustainable referrals ultimately come from rapport, trust, results, and exceptional delivery The takeaway: Stop trying to perfect the sale. Perfect the process. Build trust, find the truth of the patient's problem, communicate it with certainty, and then deliver. Keep Charging! MoChihChu!   Ask a Question for a Future Episode! Apply to work with our coaches! Join Susan's monthly CA webinars Join us at our next seminars! Join the Rhino Digital Training!

What can a GI-MAP stool test actually tell you about eczema and gut health?In this episode, Julia breaks down the GI-MAP test from an eczema perspective and walk through real patient cases to show you some of the gut findings she commonly sees in people dealing with eczema, hives, and other inflammatory skin conditions.We'll talk about gut bacteria, opportunistic microbes, H. pylori, beneficial bacteria, digestive function, immune markers, and more.Whether you've been considering a GI-MAP yourself or you're simply curious about the gut-skin connection, this episode will help you understand what these results can (and can't) tell you.⚠️ Disclaimer: This video is for educational purposes only and is not medical advice or a substitute for individualized care. Stool testing should be interpreted in the context of your symptoms and clinical history with a qualified healthcare professional.

The autopsy reports for University of Idaho students Madison Mogen, Kaylee Goncalves, Xana Kernodle and Ethan Chapin documented the extraordinary violence of the November 13, 2022 murders inside the King Road residence in Moscow. Spokane County Chief Medical Examiner Dr. Veena Singh determined that all four died from multiple sharp-force injuries consistent with a large fixed-blade knife, including a weapon such as the Ka-Bar prosecutors said was used in the killings. Mogen suffered 28 stab wounds, including extensive injuries to her face, neck and upper body that damaged major blood vessels, a lung and her liver. Chapin suffered fewer wounds than the three women, but his injuries included devastating wounds to the neck and major blood vessels, including one wound reportedly measuring approximately seven inches deep. Singh concluded that all four victims experienced a high degree of pain or suffering before death, although Chapin's suffering was assessed as occurring to a lesser degree than that of the other victims.The reports provided particularly disturbing new details about Kernodle and Goncalves. Kernodle suffered numerous wounds across her head, neck, chest, abdomen, back and extremities, including injuries to her heart, lung and major blood vessels, and her autopsy was the only one that specifically identified injuries consistent with defensive wounds, supporting the conclusion that she attempted to fight off her attacker. Goncalves suffered a combination of sharp-force and blunt-force trauma that the medical examiner described as more severe in certain respects than the injuries suffered by the others; her injuries included bleeding around the brain, a fractured nose, significant facial trauma and a knocked-out tooth, as well as evidence suggesting that an object had been pressed across her mouth. Taken together, the newly disclosed autopsy findings provided a much clearer medical picture of what occurred inside the house and demonstrated that this was not simply a series of quick fatal stab wounds, but an exceptionally violent attack in which the four victims suffered extensive and, in some cases, markedly different injuries before their deaths.to contact me:bobbycapucci@protonmail.comsource:012725+Exhibits+S-1+and+S-1+a-e+to+States+Supp+Resp+to+Rqst+for+Disc+RE+Penalty+Phase+Experts.pdf - Google Drive

The autopsy reports for University of Idaho students Madison Mogen, Kaylee Goncalves, Xana Kernodle and Ethan Chapin documented the extraordinary violence of the November 13, 2022 murders inside the King Road residence in Moscow. Spokane County Chief Medical Examiner Dr. Veena Singh determined that all four died from multiple sharp-force injuries consistent with a large fixed-blade knife, including a weapon such as the Ka-Bar prosecutors said was used in the killings. Mogen suffered 28 stab wounds, including extensive injuries to her face, neck and upper body that damaged major blood vessels, a lung and her liver. Chapin suffered fewer wounds than the three women, but his injuries included devastating wounds to the neck and major blood vessels, including one wound reportedly measuring approximately seven inches deep. Singh concluded that all four victims experienced a high degree of pain or suffering before death, although Chapin's suffering was assessed as occurring to a lesser degree than that of the other victims.The reports provided particularly disturbing new details about Kernodle and Goncalves. Kernodle suffered numerous wounds across her head, neck, chest, abdomen, back and extremities, including injuries to her heart, lung and major blood vessels, and her autopsy was the only one that specifically identified injuries consistent with defensive wounds, supporting the conclusion that she attempted to fight off her attacker. Goncalves suffered a combination of sharp-force and blunt-force trauma that the medical examiner described as more severe in certain respects than the injuries suffered by the others; her injuries included bleeding around the brain, a fractured nose, significant facial trauma and a knocked-out tooth, as well as evidence suggesting that an object had been pressed across her mouth. Taken together, the newly disclosed autopsy findings provided a much clearer medical picture of what occurred inside the house and demonstrated that this was not simply a series of quick fatal stab wounds, but an exceptionally violent attack in which the four victims suffered extensive and, in some cases, markedly different injuries before their deaths.to contact me:bobbycapucci@protonmail.comsource:012725+Exhibits+S-1+and+S-1+a-e+to+States+Supp+Resp+to+Rqst+for+Disc+RE+Penalty+Phase+Experts.pdf - Google Drive

The autopsy reports for University of Idaho students Madison Mogen, Kaylee Goncalves, Xana Kernodle and Ethan Chapin documented the extraordinary violence of the November 13, 2022 murders inside the King Road residence in Moscow. Spokane County Chief Medical Examiner Dr. Veena Singh determined that all four died from multiple sharp-force injuries consistent with a large fixed-blade knife, including a weapon such as the Ka-Bar prosecutors said was used in the killings. Mogen suffered 28 stab wounds, including extensive injuries to her face, neck and upper body that damaged major blood vessels, a lung and her liver. Chapin suffered fewer wounds than the three women, but his injuries included devastating wounds to the neck and major blood vessels, including one wound reportedly measuring approximately seven inches deep. Singh concluded that all four victims experienced a high degree of pain or suffering before death, although Chapin's suffering was assessed as occurring to a lesser degree than that of the other victims.The reports provided particularly disturbing new details about Kernodle and Goncalves. Kernodle suffered numerous wounds across her head, neck, chest, abdomen, back and extremities, including injuries to her heart, lung and major blood vessels, and her autopsy was the only one that specifically identified injuries consistent with defensive wounds, supporting the conclusion that she attempted to fight off her attacker. Goncalves suffered a combination of sharp-force and blunt-force trauma that the medical examiner described as more severe in certain respects than the injuries suffered by the others; her injuries included bleeding around the brain, a fractured nose, significant facial trauma and a knocked-out tooth, as well as evidence suggesting that an object had been pressed across her mouth. Taken together, the newly disclosed autopsy findings provided a much clearer medical picture of what occurred inside the house and demonstrated that this was not simply a series of quick fatal stab wounds, but an exceptionally violent attack in which the four victims suffered extensive and, in some cases, markedly different injuries before their deaths.to contact me:bobbycapucci@protonmail.comsource:012725+Exhibits+S-1+and+S-1+a-e+to+States+Supp+Resp+to+Rqst+for+Disc+RE+Penalty+Phase+Experts.pdf - Google DriveBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-epstein-chronicles--5003294/support.

The autopsy reports for University of Idaho students Madison Mogen, Kaylee Goncalves, Xana Kernodle and Ethan Chapin documented the extraordinary violence of the November 13, 2022 murders inside the King Road residence in Moscow. Spokane County Chief Medical Examiner Dr. Veena Singh determined that all four died from multiple sharp-force injuries consistent with a large fixed-blade knife, including a weapon such as the Ka-Bar prosecutors said was used in the killings. Mogen suffered 28 stab wounds, including extensive injuries to her face, neck and upper body that damaged major blood vessels, a lung and her liver. Chapin suffered fewer wounds than the three women, but his injuries included devastating wounds to the neck and major blood vessels, including one wound reportedly measuring approximately seven inches deep. Singh concluded that all four victims experienced a high degree of pain or suffering before death, although Chapin's suffering was assessed as occurring to a lesser degree than that of the other victims.The reports provided particularly disturbing new details about Kernodle and Goncalves. Kernodle suffered numerous wounds across her head, neck, chest, abdomen, back and extremities, including injuries to her heart, lung and major blood vessels, and her autopsy was the only one that specifically identified injuries consistent with defensive wounds, supporting the conclusion that she attempted to fight off her attacker. Goncalves suffered a combination of sharp-force and blunt-force trauma that the medical examiner described as more severe in certain respects than the injuries suffered by the others; her injuries included bleeding around the brain, a fractured nose, significant facial trauma and a knocked-out tooth, as well as evidence suggesting that an object had been pressed across her mouth. Taken together, the newly disclosed autopsy findings provided a much clearer medical picture of what occurred inside the house and demonstrated that this was not simply a series of quick fatal stab wounds, but an exceptionally violent attack in which the four victims suffered extensive and, in some cases, markedly different injuries before their deaths.to contact me:bobbycapucci@protonmail.comsource:012725+Exhibits+S-1+and+S-1+a-e+to+States+Supp+Resp+to+Rqst+for+Disc+RE+Penalty+Phase+Experts.pdf - Google Drive

The autopsy reports for University of Idaho students Madison Mogen, Kaylee Goncalves, Xana Kernodle and Ethan Chapin documented the extraordinary violence of the November 13, 2022 murders inside the King Road residence in Moscow. Spokane County Chief Medical Examiner Dr. Veena Singh determined that all four died from multiple sharp-force injuries consistent with a large fixed-blade knife, including a weapon such as the Ka-Bar prosecutors said was used in the killings. Mogen suffered 28 stab wounds, including extensive injuries to her face, neck and upper body that damaged major blood vessels, a lung and her liver. Chapin suffered fewer wounds than the three women, but his injuries included devastating wounds to the neck and major blood vessels, including one wound reportedly measuring approximately seven inches deep. Singh concluded that all four victims experienced a high degree of pain or suffering before death, although Chapin's suffering was assessed as occurring to a lesser degree than that of the other victims.The reports provided particularly disturbing new details about Kernodle and Goncalves. Kernodle suffered numerous wounds across her head, neck, chest, abdomen, back and extremities, including injuries to her heart, lung and major blood vessels, and her autopsy was the only one that specifically identified injuries consistent with defensive wounds, supporting the conclusion that she attempted to fight off her attacker. Goncalves suffered a combination of sharp-force and blunt-force trauma that the medical examiner described as more severe in certain respects than the injuries suffered by the others; her injuries included bleeding around the brain, a fractured nose, significant facial trauma and a knocked-out tooth, as well as evidence suggesting that an object had been pressed across her mouth. Taken together, the newly disclosed autopsy findings provided a much clearer medical picture of what occurred inside the house and demonstrated that this was not simply a series of quick fatal stab wounds, but an exceptionally violent attack in which the four victims suffered extensive and, in some cases, markedly different injuries before their deaths.to contact me:bobbycapucci@protonmail.comsource:012725+Exhibits+S-1+and+S-1+a-e+to+States+Supp+Resp+to+Rqst+for+Disc+RE+Penalty+Phase+Experts.pdf - Google DriveBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-epstein-chronicles--5003294/support.

The autopsy reports for University of Idaho students Madison Mogen, Kaylee Goncalves, Xana Kernodle and Ethan Chapin documented the extraordinary violence of the November 13, 2022 murders inside the King Road residence in Moscow. Spokane County Chief Medical Examiner Dr. Veena Singh determined that all four died from multiple sharp-force injuries consistent with a large fixed-blade knife, including a weapon such as the Ka-Bar prosecutors said was used in the killings. Mogen suffered 28 stab wounds, including extensive injuries to her face, neck and upper body that damaged major blood vessels, a lung and her liver. Chapin suffered fewer wounds than the three women, but his injuries included devastating wounds to the neck and major blood vessels, including one wound reportedly measuring approximately seven inches deep. Singh concluded that all four victims experienced a high degree of pain or suffering before death, although Chapin's suffering was assessed as occurring to a lesser degree than that of the other victims.The reports provided particularly disturbing new details about Kernodle and Goncalves. Kernodle suffered numerous wounds across her head, neck, chest, abdomen, back and extremities, including injuries to her heart, lung and major blood vessels, and her autopsy was the only one that specifically identified injuries consistent with defensive wounds, supporting the conclusion that she attempted to fight off her attacker. Goncalves suffered a combination of sharp-force and blunt-force trauma that the medical examiner described as more severe in certain respects than the injuries suffered by the others; her injuries included bleeding around the brain, a fractured nose, significant facial trauma and a knocked-out tooth, as well as evidence suggesting that an object had been pressed across her mouth. Taken together, the newly disclosed autopsy findings provided a much clearer medical picture of what occurred inside the house and demonstrated that this was not simply a series of quick fatal stab wounds, but an exceptionally violent attack in which the four victims suffered extensive and, in some cases, markedly different injuries before their deaths.to contact me:bobbycapucci@protonmail.comsource:012725+Exhibits+S-1+and+S-1+a-e+to+States+Supp+Resp+to+Rqst+for+Disc+RE+Penalty+Phase+Experts.pdf - Google Drive

The autopsy reports for University of Idaho students Madison Mogen, Kaylee Goncalves, Xana Kernodle and Ethan Chapin documented the extraordinary violence of the November 13, 2022 murders inside the King Road residence in Moscow. Spokane County Chief Medical Examiner Dr. Veena Singh determined that all four died from multiple sharp-force injuries consistent with a large fixed-blade knife, including a weapon such as the Ka-Bar prosecutors said was used in the killings. Mogen suffered 28 stab wounds, including extensive injuries to her face, neck and upper body that damaged major blood vessels, a lung and her liver. Chapin suffered fewer wounds than the three women, but his injuries included devastating wounds to the neck and major blood vessels, including one wound reportedly measuring approximately seven inches deep. Singh concluded that all four victims experienced a high degree of pain or suffering before death, although Chapin's suffering was assessed as occurring to a lesser degree than that of the other victims.The reports provided particularly disturbing new details about Kernodle and Goncalves. Kernodle suffered numerous wounds across her head, neck, chest, abdomen, back and extremities, including injuries to her heart, lung and major blood vessels, and her autopsy was the only one that specifically identified injuries consistent with defensive wounds, supporting the conclusion that she attempted to fight off her attacker. Goncalves suffered a combination of sharp-force and blunt-force trauma that the medical examiner described as more severe in certain respects than the injuries suffered by the others; her injuries included bleeding around the brain, a fractured nose, significant facial trauma and a knocked-out tooth, as well as evidence suggesting that an object had been pressed across her mouth. Taken together, the newly disclosed autopsy findings provided a much clearer medical picture of what occurred inside the house and demonstrated that this was not simply a series of quick fatal stab wounds, but an exceptionally violent attack in which the four victims suffered extensive and, in some cases, markedly different injuries before their deaths.to contact me:bobbycapucci@protonmail.comsource:012725+Exhibits+S-1+and+S-1+a-e+to+States+Supp+Resp+to+Rqst+for+Disc+RE+Penalty+Phase+Experts.pdf - Google DriveBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-epstein-chronicles--5003294/support.

All links and images can be found on CISO Series This week's episode is hosted by me, David Spark, producer of CISO Series and Mike Johnson, CISO, Rivian. Joining us is Nada Noaman, SVP and CISO, Estee Lauder Companies. In this episode: Skipping the apprenticeship Privileged users nobody manages like one Findings without the authority to fix them Security was always behavioral A huge thanks to our sponsor, Native The Cloud Security Control Plane. Native helps enterprises turn built-in cloud security controls into active, operational defenses across AWS, Azure, Google Cloud, and OCI, so teams can enforce secure-by-design architecture at the source, preview impact before rollout, and keep guardrails aligned as cloud environments change. Learn more at native.security.  

New Mexico's legislative “truth commission” investigating Jeffrey Epstein's activities in the state released its initial 119-page report, concluding that authorities had failed for years to adequately investigate what occurred at Epstein's Zorro Ranch near Santa Fe. The commission said federal investigators had concentrated primarily on Epstein's crimes in New York, Florida and the U.S. Virgin Islands while allegations involving New Mexico were largely left unexplored. The report also criticized state and local authorities for relying on federal agencies rather than aggressively investigating potential crimes within New Mexico themselves. Lawmakers said the commission's work was intended to determine not only what happened at the ranch, but whether failures, negligence or possible public corruption allowed Epstein to operate there with little scrutiny for decades.The initial report did not appear to unveil a large body of previously unknown evidence, instead assembling information from public records, prior reporting, released Epstein documents and survivor accounts as the commission continued its investigation. Among the testimony considered was that of survivor Rachel Benavidez, who alleged that Epstein abused her at Zorro Ranch in the late 1990s. The commission's release came as New Mexico Attorney General Raúl Torrez was separately pursuing a reopened criminal investigation and suing the Justice Department for records he said federal officials had refused to provide. Together, the legislative inquiry and the attorney general's investigation represented a renewed effort to examine Epstein's New Mexico operation, identify who may have participated or enabled it, and determine why meaningful scrutiny of Zorro Ranch had taken so long.to contact me:bobbycapucci@protonmail.comsource:New Mexico's legislative truth commission on Epstein releases initial report | News | santafenewmexican.com

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Nick Shirley is a documentary filmmaker and YouTuber known for immersive, on-the-ground videos exploring overlooked communities, subcultures, and social issues around the world. His independent documentaries have built a large online audience by combining travel journalism with long-form, firsthand reporting.Brandon Gill is a Republican politician serving as the U.S. Representative for Texas's 26th congressional district since 2025. Before entering Congress, he worked as an investment banker, founded the conservative news outlet DC Enquirer, and built a national profile in conservative media and politics.IN THE NEWS: A New 2028 Poll Just Shook Up Both Parties; AOC in lead, Ford worker fired for allegedly stealing $8 worth of Doritos and just wants old job back, Scientists Behind Paper Dismissing Covid Lab Leak Privately Lost Confidence in Findings — but Maintained Public Stance FOR MORE WITH NICK SHIRLEY:YOUTUBE AND INSTAGRAM: @nickshirleyFOR MORE WITH BRANDON GILL:INSTAGRAM: @repbrandongillFOR MORE WITH ANDREW HOBSON:YOUTUBE: @andrewfhobsonLIVE SHOWS: July 25 - Huntington Beach, CAJuly 26 - Torrance, CA (2 Shows)July 30 - Freehold, NJ (2 Shows)July 31 - New York, NY (2 Shows)August 1 - Uncasville, CTAugust 2 - Albany, NYThank you for supporting our sponsors:BetOnlinechime.com/ADAMjackarcher.com Promo Code: GETJACKoreilly.com/ADAMPluto.tvPodcastOnehttps://www.sheath.com/ADAM use code ADAM for 20% off.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.