Podcasts about drug administration fda

Cavities are still one of America's most common diseases – despite decades of fluoride use. Xlear is calling on the FDA to recognize xylitol as an active anticaries ingredient so dental professionals and patients can finally access this powerful tool. Xylitol, a safe and natural compound, has been proven to stop cavity- causing bacteria and dramatically reduce tooth decay.The American Dental Hygienist Association (ADHA) in conjunction with Xlear, a leader in hygiene products, filed a citizen petition with the U.S. Food & Drug Administration (FDA) urging the FDA to formally recognize xylitol as an approved Over-the-Counter (OTC) active ingredient in dental hygiene products, including toothpaste, rinses, gels, mouthwashes, gums, and lozenges.Xylitol addresses the root cause of tooth decay. In contrast, fluoride strengthens tooth enamel. Fluoride has almost no effect on the bacteria that causes tooth decay. Studies have shown that xylitol has a higher “protection factor” in fighting cavities than fluoride.“Dental decay is the single most common communicable, chronic disease inflicting Americans today. Moreover, dental decay is also closely associated with driving other serious health risks - ranging from heart disease to diabetes,” said Trisha O'Hehir, MS, RDH.Key Facts:·         Nearly 90% of U.S. adults have experienced tooth decay.·         Studies show xylitol can reduce cavities by up to 80%.·         Xylitol works by neutralizing acid-producing bacteria and protecting enamel at the source.·         Xylitol is safe if swallowed, a key benefit for children.·         Widely used internationally, xylitol is already found in gum and oral hygiene products. The petition requests that FDA: Amend 21 C.F.R. Part 355 to list xylitol as an approved anti-caries active ingredient. Alternatively, issue a new OTC monograph under Section 505G of the FDCA.Learn more about the Petition hereXlear is one of the nation's leaders in effective xylitol hygiene products, available inpharmacies, big box stores, natural retailers and online.XLEAR's Retailers: Walgreens, CVS, Vitamin Shoppe, Target, Kroger, Sprouts, Natural Grocers and most natural products retailers nationwide.XLEAR's Online Retailers: Amazon, iHerb, Lucky Vitamin, and Vitacost.comLearn more at Xlear.com or SprySmile.com 

In this episode of the Heart to Heart podcast, Dr. Mike Hart interviews Dr. Corey Peacock, an exercise physiologist and department chair at Nova Southeastern University. Dr. Peacock discusses his diverse background, from establishing the Fight Science Laboratory to working with elite MMA fighters at Kill Cliff Fight Club. The conversation covers advanced training methods, including zone-based cardio, strength and conditioning exercises, and recovery protocols. Listeners gain insights into the importance of athletic balance, the role of power versus strength in MMA, and the efficacy of various recovery tools such as cold plunges, sauna, and red light therapy. Dr. Peacock emphasizes the tailored approach needed for different fighters and the benefits of continually evolving training strategies.   Dr. Corey Peacock is an exercise physiologist, sports scientist, and performance coach who bridges academic research with elite MMA training. He holds a Ph.D. in Exercise Physiology from Kent State University and serves as Department Chair of Health and Human Performance at Nova Southeastern University, where he co-founded the Fight Science Lab. As Director of Athlete Performance for Kill Cliff Fight Club, Dr. Peacock helps world-class fighters optimize strength, endurance, and recovery through science-driven performance methods. Connect with him on Instagram @drcpeacock and LinkedIn. Links: American College of Sports Medicine (ACSM) Kill Cliff Fight Club (formerly Blackzilians and Sanford MMA)  Dr. José Antonio – Co-founder of Fight Science Lab Norwegian 4x4 Interval Method    Show Notes: 00:00 Welcome back to the Hart2Heart podcast with Dr. Mike Hart 00:47 Dr. Corey Peacock's Background 02:52 Cardio Training for MMA Fighters 17:41 Strength and Conditioning Essentials 30:35 Reverse Hypers and Posterior Chain Training 34:17 Balancing Strength and Power in MMA 36:44 Training Insights from Anthony Rumble Johnson 42:42 The Role of HRV in Training Adjustments 47:13 Recovery Tools: Cold Plunges, Sauna, and Red Light Therapy 52:57 Upcoming Events and Contact Information — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  Policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

US Government Shutdown – What the FDA Can Still Be Doing? When the U.S. government experiences a shutdown, the consequences ripple across every industry — but for medical device manufacturers, the uncertainty can be alarming. In this article, Regulatory Expert Rob Packard explores what happens to the U.S. Food and Drug Administration (FDA) during a shutdown, and how it affects global manufacturers. You'll learn: Which FDA activities continue, and which are suspended How submissions like 510(k), PMA, and De Novo are impacted What happens to clinical trials, recalls, and ongoing investigations Whether this situation has happened before and how long it could last How companies can prepare and what contingency actions to take

In this solo podcast episode, Dr. Mike Hart delves into the intricacies of insulin resistance, a prevalent yet misunderstood condition. The episode covers the fundamental role of insulin, what happens during insulin resistance, and its linkage to various diseases like diabetes and heart disease. It includes a detailed discussion on how to measure insulin resistance using markers like triglyceride to HDL ratio, fasting insulin, fasting glucose, and hemoglobin A1c. Dr. Hart also explains the significance of advanced glycation end products (AGEs) and how they contribute to aging and diabetes. Practical tips on improving insulin sensitivity through diet, exercise, and supplements such as fiber, mulberry leaf extract, and berberine are provided. Additional considerations for managing blood sugar levels and preventing insulin resistance are also discussed. Links: Fasting Insulin Test: https://medlineplus.gov/lab-tests/insulin-in-blood/ Fructosamine Test: https://medlineplus.gov/lab-tests/insulin-in-blood/ Carnosine: https://examine.com/supplements/carnosine/?show_conditions=true P5P (Pyridoxal-5-Phosphate): https://examine.com/supplements/vitamin-b6/?show_conditions=true Show Notes: 00:00 Welcome back to the Hart2Heart Podcast with Dr. Mike Hart 00:56 Understanding Insulin and Insulin Resistance 03:02 Markers and Tests for Insulin Resistance 11:30 Advanced Glycation End Products (AGEs) 14:16 Exercise and Insulin Sensitivity 14:53 "Exercise keeps your body insulin sensitive for up to 48 hours — not just two." 16:21 Nutritional Strategies for Blood Sugar Control 20:59 Supplements and Medications for Blood Sugar Management — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to cutting through the noise and uncovering the most effective strategies for optimizing health, longevity, and peak performance. This podcast dives deep into evidence-based approaches to hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary. Beyond health science, we tackle the intersection of public health and politics, exposing how policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being. Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen). If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being. Connect on social with Dr. Mike Hart: Instagram: https://www.instagram.com/drmikehart/ Twitter: https://twitter.com/drmikehart Facebook: https://www.facebook.com/MikeHartEPS/

Medicus Pharma CEO Dr Raza Bokhari joined Steve Darling from Proactive to unveil a new strategic collaboration with the Gorlin Syndrome Alliance (GSA) to advance compassionate access to SKINJECT™, the company's investigational doxorubicin-containing dissolvable microneedle array therapy for basal cell carcinoma. The initiative focuses on patients with Gorlin Syndrome—also known as nevoid basal cell carcinoma syndrome—a rare genetic condition that affects an estimated 1 in 31,000 people worldwide. Individuals diagnosed with the disorder can develop hundreds or even thousands of BCCs throughout their lives, often beginning in childhood. Current treatment approaches frequently involve repeated surgeries and ongoing dermatologic interventions, resulting in significant physical scarring, emotional strain, and financial burden. Dr. Bokhari explained that the partnership with the GSA is designed to jointly pursue an Expanded Access IND Program with the U.S. Food and Drug Administration (FDA). This pathway would enable eligible Gorlin Syndrome patients with multiple, recurrent, or inoperable basal cell carcinomas to obtain supervised treatment with SKINJECT™ outside of traditional clinical trials. In addition to facilitating treatment for those with pressing unmet medical needs, the program will support the collection of real-world safety and tolerability data, which will contribute to future regulatory submissions. It will also enable greater incorporation of patient-centered insights into clinical development and long-term treatment strategies. Medicus Pharma is currently underway with its Phase 2 clinical study, SKNJCT-003, which began enrolling patients in August 2024 across nine U.S. trial sites. The study is a double-blind, placebo-controlled, triple-arm proof-of-concept trial evaluating SKINJECT™ as a non-invasive therapeutic option for skin-based BCC using proprietary dissolvable D-MNA . Dr. Bokhari emphasized that the collaboration with the GSA reflects Medicus Pharma's mission to bring innovative, patient-friendly cancer treatments to those most in need, while advancing SKINJECT™ toward broader clinical and commercial milestones. #proactiveinvestors #nasdaq #mdcx #tsxv #mdcx #pharma #Biotech #CancerTreatment #ClinicalTrials #FDAApproval #SkinCancer #HealthcareInnovation #Investing #MedicalResearch #SkinCancer #BasalCellCarcinoma #BiotechNews #CancerResearch #GorlinSyndrome #BasalCellCarcinoma #CompassionateUse #FDAApproval #RareDiseaseTreatment #NoninvasiveTherapy #BiotechNews

Elinzanetant, sold under the brand name Lynkuet, receivedapproval from the U.S. Food and Drug Administration (FDA) on October 24, 2025, for the treatment of moderate to severe hot flashes due to menopause.  How is this different than Fezolinetant, which was approved in 2023? Listen in for details. 1.   Menegaz de Almeida, Artur MS; Oliveira, Paloma MS; Lopes, Lucca MD; Leite, Marianna MS; Morbach, Victória MS; Alves Kelly, Francinny MD; Barros, Ítalo MS; Aquino de Moraes, Francisco Cezar MS; Prevedello, Alexandra MD. Fezolinetant and Elinzanetant Therapy for Menopausal Women Experiencing Vasomotor Symptoms: A Systematic Review and Meta-analysis. Obstetrics & Gynecology 145(3):p 253-261, March 2025. | DOI: 10.1097/AOG.00000000000058122.     Pinkerton JV, Simon JA, Joffe H, Maki PM, NappiRE, Panay N, Soares CN, Thurston RC, Caetano C, Haberland C, Haseli Mashhadi N, Krahn U, Mellinger U, Parke S, Seitz C, Zuurman L. Elinzanetant for the Treatment of Vasomotor Symptoms Associated With Menopause: OASIS 1 and 2 Randomized Clinical Trials. JAMA. 2024 Aug 22;332(16):1343–54. doi: 10.1001/jama.2024.14618. Epub ahead of print. PMID: 39172446; PMCID: PMC11342219.3.     Cardoso F, Parke S, Brennan DJ, Briggs P,Donders G, Panay N, Haseli-Mashhadi N, Block M, Caetano C, Francuski M, Haberland C, Laapas K, Seitz C, Zuurman L. Elinzanetant for Vasomotor Symptomsfrom Endocrine Therapy for Breast Cancer. N Engl J Med. 2025 Aug 21;393(8):753-763. doi: 10.1056/NEJMoa2415566. Epub 2025 Jun 2. PMID: 40454634.STRONG COFFEE PROMO: 20% Off Strong CoffeeCompany https://strongcoffeecompany.com/discount/CHAPANOSPINOBG

  In this episode, host Dr. Mike Hart welcomes neuroscientist and author Dr. Ben Rein to discuss his new book, 'Why Brains Need Friends: The Neuroscience of Social Connection.' Dr. Rein shares his journey in neuroscience, his research on autism and MDMA, and his pivot towards science communication. They delve into the devastating effects of loneliness, comparing its impact on mortality to smoking 15 cigarettes a day, and explore why human connections are critical for our brain health. Dr. Rein also discusses the benefits of having pets, the intricate balance of social interactions across a lifespan, the effects of MDMA on feelings of connection, and the role of oxytocin in social bonding. This episode provides a deep dive into the science behind social interactions, offering actionable insights to improve mental health and wellbeing.   Dr. Ben Rein is a neuroscientist, educator, and science communicator whose work explores the biology of human connection, empathy, and social behavior. With a Ph.D. in neuroscience and postdoctoral research at Stanford University, Dr. Rein has studied everything from the neural underpinnings of autism spectrum disorder to how MDMA (ecstasy) enhances empathy in the brain.   Follow his work at mindscience.org or connect with him on Instagram.   Links: Oxytocin (“the love hormone”) Loneliness and mortality studies Stanford University Lion's Mane   Show Notes: 00:00 Welcome back to the Hart2Heart podcast with Dr. Mike Hart 00:30 Dr. Ben Rein's background and new book 02:30 The loneliness epidemic and its effects 04:00 The science behind social interaction 04:15 “ Being isolated is worse for you or as bad for you as smoking 15 cigarettes a day.” 10:30 Extroversion vs. introversion: social needs 24:00 Oxytocin: the love hormone 33:00 Teamwork and social bonds 36:30 The power of tribalism in sports 38:00 Romantic relationships and health 42:00 The impact of loneliness across a lifetime 49:00 Social media and loneliness 01:02:00 The therapeutic potential of MDMA — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  Policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

This episode, hosted by Etienne Nichols, delves into the critical impact of a U.S. government shutdown on the medical device industry, specifically focusing on the Food and Drug Administration (FDA). Guest Michael Nilo, President and Principal Consultant of Nilo Medical Consulting Group and a former FDA Scientific Reviewer, offers an insider's perspective on which FDA functions halt and which remain active during a funding lapse. He clarifies that while the processing of new, user-fee-supported marketing applications like PMAs and 510(k)s typically stops, essential activities like active review of already-filed submissions, post-market safety surveillance, enforcement of recalls, and Investigational Device Exemption (IDE) reviews continue, drawing on existing user fee reserves.The discussion pivots to the significant slowdowns that occur, notably the suspension of non-MDUFA-goal-tied interactions, such as Q-submissions (Pre-Submissions) and most interactive reviews. For startups and small manufacturers, the halting of the crucial small business designation processing can be particularly detrimental, leading to astronomically higher user fees once the government reopens. Michael emphasizes that the industry should anticipate this political risk and plan submission timelines strategically, positioning a government shutdown as an "uncontrollable natural disaster" that requires proactive risk mitigation.Michael provides actionable advice for MedTech leaders to pivot during a shutdown. He recommends using the enforced delay to significantly improve the quality of submissions—making them easier to navigate and review once the FDA is fully operational—to gain a crucial advantage over the backlog of queued submissions. Furthermore, companies should utilize the time to focus on parallel activities such as process validation, refining quality systems, and strengthening commercial and reimbursement strategies. Michael stresses the importance of remembering the core mission: getting life-improving technologies to patients, and using any delay as an opportunity to emerge stronger and more prepared for commercial launch.Key Timestamps1:45 - The initial effects of a shutdown: What truly stops at the FDA (new submissions) versus what keeps running (existing reviews, IDEs, post-market surveillance).3:50 - Why active review of filed submissions continues—the role of the user fee "reserve."5:58 - Critical functions that stop or slow down: Pre-submissions (Q-subs), interactive reviews, new policy guidance, and routine inspections.7:25 - The major impact of halting the small business designation process on user fees for new manufacturers.8:36 - MDUFA (Medical Device User Fee Amendments) explained: How user fees fund the FDA and maintain operations during a lapse.11:51 - Direct effects on a MedTech company's runway and the loss of interactive review.13:17 - Actionable advice: Improving submission quality for easier review to mitigate the post-shutdown backlog.15:00 - Strategic pivot: Focusing on parallel work like process validation and quality system refinement.16:03 - Communicating with investors and partners: Positioning the shutdown as an uncontrollable event and shortening the commercial launch gap.18:50 - Looking ahead: Planning submissions around budget resolution deadlines to anticipate shutdown risk.20:53 - Final advice: Keeping the patient-focused mission in mind and maximizing internal...

Dr. Mark McClellan has served as a Member of the President's Council of Economic Advisors, Administrator of the Centers for Medicare & Medicaid Services (CMS), and Commissioner of the U.S. Food and Drug Administration (FDA). But his experiences before, and accomplishments following these leadership roles at the highest levels of government health policy are equally important to his perspective on the healthcare ecosystem – especially during a time of rapid policy change.Dr. McClellan always intended on pursuing a medical degree and entered a joint Harvard-MIT program that took him in a slightly different direction. He ended up studying economics and the rising cost of healthcare at MIT. He ultimately earned a medical degree from the Harvard-MIT Division of Health Sciences and Technology, a Ph.D. in economics from MIT, and a master's in public administration from Harvard's Kennedy School.Dr. McClellan began his career at the Treasury Department in the Clinton Administration, and returned to public service under the George W. Bush Administration where he led the FDA and CMS. Today, Dr. McClellan is the Robert J. Margolis, M.D., Professor of Business, Medicine and Policy at Duke University and the founding Director of the Duke-Margolis Institute for Health Policy. His work centers on improving health care through policy and research, with a focus on payment reforms, quality, value, and biomedical innovation.With his expertise in medicine, economics and public policy, Dr. McClellan talked to Keith Figlioli in this episode of Healthcare is Hard to share his perspective on adapting to rapid change in the current healthcare landscape. Topics they discussed include:Misalignment of innovation and outcomes. While advancements in digital health are coming to market faster than ever before, Dr. McClellan says there's still a lack of technology truly centered on keeping patients healthy. He says traditional payment methods make it hard to support this type of innovation. For example, advancements in AI are helping physicians gather information for prior authorization requests, and ambient scribing saves time with note taking and administration. But these technologies essentially help providers see more fee-for-service patients or bill for more profitable services. He argues that more outcome-oriented payments are needed to advance technology-embedded care models. The evolution of value-based care. After Congress passed the Medicare Modernization Act in 2003 to establish Medicare Advantage, Dr. McClellan became administrator of CMS at the President's request to lead its implementation. With unique insight from leading some of the earliest VBC programs, he shared his thoughts on the speed of adoption and why it hasn't happened faster. He discussed how early MA models needed to be based on existing fee-for-service infrastructure, his surprise that not much has changed, and his optimism that it's finally starting to.Mobilizing private capital for public health. Private investment will be essential to support the significant changes required to improve healthcare – especially with uncertainties around future levels of government funding. Dr. McClellan explained how the Duke-Margolis Capital Impact Council (CIC) was launched to guide and improve the role of private investment in healthcare. He described how members of the council are developing and sharing practices for investors and their portfolio companies to track health value return on investment alongside financial ROI.To hear Dr. McClellan and Keith discuss these topics and more, listen to this episode of Healthcare is Hard: A Podcast for Insiders.

  In this episode of the Heart to Heart podcast, Dr. Mike Hart chats with Dr. Jose Antonio about the evolution and impact of sports nutrition research, particularly focusing on creatine and protein consumption. Dr. Antonio shares his journey from studying muscle physiology to pioneering research in sports nutrition, highlighting the initial skepticism in the scientific community and the eventual acceptance of supplements like creatine. They also delve into the benefits of various supplements for athletic performance, the ongoing debates in the medical field regarding supplementation, and exciting upcoming research on creatine's effects on eye muscle performance in athletes.   Links: University of Central Florida – Dr. Jeff Stout University of Regina – Dr. Darren Candow (Creatine researcher) Protein Intake & High-Protein Diets Caffeine + L-Theanine Combination Show Notes: 00:00 Welcome back to the Hart2Heart Podcast with Dr. Mike Hart 00:00 Introduction and guest welcome 01:00 Dr. Jose Antonio's academic journey 01:30 Challenges in sports nutrition research 04:00 Breakthrough in sports supplements 08:00 The evolution of sports nutrition 13:00 High protein diet studies 14:20 “We had people eating 600 to 800 extra calories of pure protein—and nothing happened. No fat gain. That alone blew people's minds.” 17:00 Protein timing and intake 20:30 Impact of hormones on protein absorption 23:00 Testosterone and protein intake 24:00 Peptides and growth hormone 25:00 Protein timing and casein 25:30 Creatine for brain and muscle 42:00 Mitochondrial health and supplements   — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  Policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

David T. Dyjack, Dr.P.H., CIH has served as Executive Director and CEO of the National Environmental Health Association (NEHA) since May 2015. Dr. Dyjack's 30-year career includes expertise in environmental health, emergency preparedness and response, public health informatics, infectious disease, workforce development, governmental infrastructure, maternal and child health, health equity, and chronic disease. A board-certified industrial hygienist, Dr. Dyjack also has advanced degrees in public health with a doctorate from the University of Michigan and a master's degree from the University of Utah. In this episode of Food Safety Matters, we speak with Dr. Dyjack [36:33] about: Which demographics may make up the future food safety workforce, based on NEHA data, and what professional support they may need How the learning preferences of younger generations are shaping current education and training initiatives for the food safety sector Shifting priorities at the U.S. Food and Drug Administration (FDA) and their potential influence on the future food safety workforce Industry's role in attracting and educating the future food safety workforce, and how NEHA works with industry to help realize these goals The work of NEHA's Food Safety Committee to help address food safety workforce training gaps and emerging challenges Who can benefit from NEHA's food safety courses and certificate programs The need for additional emergency preparedness training to mitigate food safety risks associated with increasing and more severe natural disasters brought on by climate change. News and Resources Government Shutdown Affects Food Safety: HHS Furloughs Employees, FDA Pauses CORE Investigation Table, Federal Layoffs to Hit HHS Amid Government Shutdown, May Affect Food Safety Staffers [3:08] Another Death Reported in Listeria Outbreak Linked to Prepared Pasta Meals [8:09] FDA Reveals Unsolved E. Coli Outbreak in New Foodborne Illness Outbreak Transparency Tools [16:19] Fruit, Salmonella Caused Most Multistate Foodborne Illness Outbreaks in 2023, per CDC [19:16] Four-Year UK Foodborne Pathogen Surveillance Program Concludes, FSA to Launch New Initiative [23:47] USDA-FSIS Now Includes Gluten in Major Allergen Verification Activities [29:51] Sponsored by: Michigan State University Online Food Safety We Want to Hear from You! Please send us your questions and suggestions to podcast@food-safety.com

Welcome back to Diabetes Dialogue: Technology, Therapeutics, & Real-World Perspectives! In this episode, cohosts Diana Isaacs, PharmD, and Natalie Bellini, DNP, explore 3 significant developments shaping diabetes care: a novel glucose-sensing technology, the return of once-weekly insulin icodec to the US Food and Drug Administration (FDA), and changes to Eli Lilly's metabolic research pipeline. 00:00:01 Introduction 00:00:18 The Biolinq Shine 00:05:59 The Practicality of Monitoring Glucose 00:06:55 Wishlist for the Biolinq's Future 00:08:38 Insulin Icodec Resubmission 00:10:21 Benefits of Once-Weekly Insulin 00:14:00 International Success Stories 00:15:28 Eli Lilly Cancels Bimagrumab for T2D 00:18:36 Bimagrumab Still in Testing for Obesity 00:22:49 Outro

On this episode of BloodStream, hosts Patrick James Lynch and Amy Board share stories of remarkable achievement and progress in bleeding disorders. Hear from Tim Stowers, a severe hemophilia A patient who has summited Everest and completed solo English Channel swims, as he shares his journey of resilience and determination. Plus, get the latest updates on Star Therapeutics' lead VWD therapy, now entering a pivotal Phase 3 trial, and learn how patients can help shape the first validated VWD quality-of-life assessment tool.   Presenting Sponsor: Takeda, visit bleedingdisorders.com to learn more. Show Notes:   Star's Pivotal Phase 3 Study (VIVID-6) Initiated:   VGA039 is the first subcutaneous therapy, dosed once monthly, that has the potential to address all types of VWD and all types of bleeds. It has also received Fast Track and orphan drug designation from the United States Food and Drug Administration (FDA). The additional investment announced today supports our continued global clinical expansion as we advance into our pivotal, Phase 3 trial.   Explore clinical trial eligibility: visit THIS WEBSITE    To participate in the first validated VWD quality of life patient-reported outcome tool, please e-mail Judith.Monickaraj@chet.rochester.edu to learn more. Subscribe: The BloodStream Podcast   Connect with BloodStream Media: BloodStreamMedia.com BloodStream on Facebook  BloodStream on X/Twitter  BloodStream on Instagram BloodStream on LinkedIn BloodStream on TikTok  

Send us a textDr. Michael McCullar, PhD is Chief Executive Officer  of RegCell ( https://regcellbio.com/ ), a biotechnology company has developed a best-in-class proprietary platform that allows the generation of epigenetically reprogrammed antigen-specific regulatory T-cells (Tregs) that are stable in vivo and maintain a high degree of functionality (S/F-Epigen-Tregs) to restore immune tolerance and ultimately reverse autoimmune disorders as well as the limitations with transplantation.Dr. McCullar has a wealth of experience in the biotech and pharmaceutical industries, spanning more than two decades. Throughout his career, he has been involved in various aspects of drug development and played pivotal roles in the success of several pharmaceutical companies. Dr. McCullar formerly served as the CEO of OnQuality Pharmaceuticals, where he provided executive leadership to this targeted oncology supportive therapy company focused on developing pioneering medications tailored to address the intricacies of cancer treatment-related toxicities. Before that, he was Chief Operating Officer at Tolero Pharmaceuticals, where he had a prominent role in the company's acquisition by Sumitomo Dainippon Pharma and also served as the Senior Vice President of Business Development at Astex Pharmaceuticals, during it's acquisition by Otsuka Pharmaceuticals. Dr. McCullar has held several high-level executive positions at SuperGen, showcasing his commitment and upward career path within the company. His journey at SuperGen culminated in the role of Senior Vice President of Strategy and Operations, where his expertise paved the way for the U.S. Food and Drug Administration (FDA) approval of Dacogen as a treatment for myelodysplastic syndromes, and the acquisition of Astex Therapeutics, which resulted in the formation of Astex Pharmaceuticals, Inc.Dr. McCullar holds a Ph.D. in Toxicology from the University of California, Riverside and an MBA from the W.P. Carey School of Business at Arizona State University.#MichaelMcCullar #RegCell #RegulatoryTCells #Tregs #AutoimmuneDisorders #Transplantation #ShimonSakaguchi #ImmuneSystem #SelfAntigens #Tolerance #AntiInflammatoryCytokines #AntigenPresentingCells #Thymus #BoneMarrow #Anergy #AntigenSpecificTregs #AntigenTargeting #Homing #EpigeneticEditing #Reprogramming #AutologousManufacturing #Japan #ProgressPotentialAndPossibilities #IraPastor #Podcast #Podcaster #ViralPodcast #STEM #Innovation #Technology #Science #ResearchSupport the show

It's Thursday, October 9th, A.D. 2025. This is The Worldview in 5 Minutes heard on 140 radio stations and at www.TheWorldview.com.  I'm Adam McManus. (Adam@TheWorldview.com) By Jonathan Clark Pakistani pastor dies after 13-year jail sentence A pastor in Pakistan died on Sunday after languishing in prison for 13 years. Pastor Zafar Bhatti founded Jesus World Mission Church ministry. Back in 2012, he was falsely accused of insulting Islam. Authorities finally overturned his conviction this month, releasing him last Wednesday. The 62-year-old pastor died days after from cardiac arrest at his home.   The British Asian Christian Association helped defend the pastor in court. The organization stated, “Though his earthly journey has ended, Zafar's faith, endurance, and ultimate vindication remain a powerful testament to hope in Christ amidst persecution.” Nigerian Anglican Church appalled that woman chosen to be new church head The Anglican Church of Nigeria declared spiritual independence from the Church of England on Tuesday. The announcement came in response to the Church of England's appointment of Sarah Mullally as the Archbishop of Canterbury. She is the first woman to hold the position. She also supports abortion and faux homosexual marriage.  Archbishop Henry Ndukuba is the Primate of the Church of Nigeria. He stated, “[Mullally's] appointment marks a tragic departure from biblical orthodoxy. . . . We remain Anglicans — but not under Canterbury. Our loyalty is to Christ and the truth of His Word, not to institutions that have abandoned it.” Police arrest man intent on blowing up church with Supreme Court Justices In the United States, police arrested a man on Sunday who had hundreds of explosive devises outside of St. Matthews Cathedral in Washington, D.C. Police made the arrest before an annual service traditionally attended by U.S. Supreme Court justices.  According to court records, the man's notebook expressed animosity toward Supreme Court justices, the Catholic Church, Jews, and immigration enforcement officials.  FBI cuts ties with God-hating Southern Poverty Law Center The Federal Bureau of Investigation announced last week it has cut ties with the Southern Poverty Law Center. The far-left nonprofit is known for listing conservative and Christian organizations as “hate groups,”  primarily because they affirm God's design for sexuality and marriage. FBI Director Kash Patel posted on X, “The Southern Poverty Law Center long ago abandoned civil rights work and turned into a partisan smear machine. Their so-called ‘hate map' has been used to defame mainstream Americans and even inspired violence. That disgraceful record makes them unfit for any FBI partnership.” Florida, Louisiana, Missouri & Texas sue FDA over mail-order Abortion Kill Pill The state of Louisiana joined a lawsuit against the Food and Drug Administration on Monday.  Florida, Missouri, and Texas are also on the case. They are challenging the FDA's 2023 policy that allows mail-order abortion drugs. Louisiana's filing states, “Every year, doctors and activists in states like California and New York mail a U.S. Food and Drug Administration (FDA)-approved abortion drug called mifepristone to thousands of Louisiana residents for the express purpose of causing abortions in Louisiana that are blatantly unlawful.” Gold hit $4,000 per ounce first time ever On Tuesday, spot gold prices hit $4,000 per ounce for the first time in history.  That's up 50% from January. Silver is up 60% this year. The demand for gold is up as investors hedge against economic uncertainty.  Financial analyst Rhona O'Connell told Reuters, “Background factors are much the same as before, in terms of geopolitical uncertainty, with the added spice of the (U.S.) government shutdown.” Prison Fellowship and Bible League to send 620,000 Bibles to prisoners And finally, Prison Fellowship International and Bible League International are partnering to distribute over half a million Bibles. The 620,000 Bibles will go to prisoners in 20 countries over the next five years. Frank Lofaro with Prison Fellowship International said, “God's Word has the power to reach prisoners in their darkest moments with the light of Jesus Christ. Through this partnership, prisoners who come to know Jesus through our evidence-based, in-prison programs are equipped to grow in their faith through a Bible that they can understand and that speaks to their circumstances.” Luke 4:18 says, “The Spirit of the LORD is upon Me, because He has anointed Me to preach the gospel to the poor; He has sent Me to heal the brokenhearted, to proclaim liberty to the captives and recovery of sight to the blind, to set at liberty those who are oppressed.” Close And that's The Worldview on this Thursday, October 9th, in the year of our Lord 2025. Follow us on X or subscribe for free by Spotify, Amazon Music, or by iTunes or email to our unique Christian newscast at www.TheWorldview.com.  I'm Adam McManus (Adam@TheWorldview.com). Seize the day for Jesus Christ.

In this episode of the Heart to Heart podcast, Dr. Mike Hart sits down with Dr. Ted Naiman, a family medicine physician from Seattle with a passion for diet and exercise. They discuss the importance of family physicians in healthcare, Dr. Naiman's personal fitness transformation focusing on a high-protein, low-carb diet, and the significance of satiety over counting calories. Dr. Naiman shares his views on effective exercise routines, optimal macronutrient ratios, and the advantages of front-loading protein. They also delve into insulin resistance, the use of fasting triglycerides as a marker, and the potential of GLP-1 medications for weight loss and insulin sensitivity. This comprehensive discussion provides actionable insights into improving metabolic health and body composition. Dr. Ted Naiman is a family physician, author, and leading voice in evidence-based nutrition and metabolic health. With over two decades of experience in primary care, Dr. Naiman has dedicated his career to helping people understand the science of body composition, satiety, and sustainable weight management. Learn more at tednaiman.com  and on LinkedIn.   Links: The P:E Diet — by Dr. Ted Naiman Fairlife Milk (ultra-filtered milk)   Show Notes: 00:00 Welcome back to the Hart2Heart Podcast with Dr. Mike Hart 00:30 Dr. Ted Naiman's background 01:30 Transformation journey 02:00 Diet and exercise philosophy 03:00 Calorie counting debate 05:30 Macro ratios and protein focus 09:30 Daily meal timing and strategy 13:27 “Front-load your protein. If you start your day with donuts, you'll eat more all day. If you start with protein, you'll automatically eat less.” 20:30 Sources of protein 25:00 Carbohydrate choices 29:00 Fat sources and supplementation 34:00 Understanding insulin resistance 37:30 Understanding insulin sensitivity and resistance 39:00 Indicators of insulin resistance: triglycerides and HDL 43:30 The role of fasting insulin and glucose 50:30 Training recommendations: cardio vs. weights 52:30 Effective resistance training strategies 59:30 Visceral fat: causes and reduction strategies 01:05:30 The role of GLP-1 in weight management 01:14:30 Conclusion and final thoughts   — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  Policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

Essential oils are concentrated plant extracts obtained through distillation and pressing. This process captures the aromatic compounds responsible for the oils' fragrance and therapeutic effects The U.S. Food and Drug Administration (FDA) designates some oils as Generally Recognized as Safe (GRAS), meaning food-grade oils are safe to ingest in tiny amounts GRAS essential oils like peppermint, lemon, ginger, cinnamon, and basil can be used to flavor foods and beverages. This reflects their culinary value when used sparingly Other essential oils, such as lavender, eucalyptus, tea tree, rosemary, chamomile, wintergreen, and camphor, are best suited for aromatic or topical use Whether in food, through scent, or applied to the skin, essential oils support wellness when used with care and intention

It's In the News.. a look at the top headlines and stories in the diabetes community. This week's top stories: Sanofi lowers prices, oral pill for T1D prevention studied, updates from Medtronic, Tandem, and Sequel Med Tech, falsely lower A1Cs (and why that happens), Biolinq gets FDA okay for micro-needle CGM and more! Find out more about Moms' Night Out  Please visit our Sponsors & Partners - they help make the show possible! Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com) Omnipod - Simplify Life Learn about Dexcom   Check out VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Twitter Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com  Reach out with questions or comments: info@diabetes-connections.com Episode transcription with links:   Hello and welcome to Diabetes Connections In the News! I'm Stacey Simms and every other Friday I bring you a short episode with the top diabetes stories and headlines happening now. XX French drugmaker Sanofi says it would offer a month's supply of any of its insulin products for $35 to all patients in the U.S. with a valid prescription, regardless of insurance status. The program, originally meant for uninsured diabetes patients, would now include those with commercial insurance or Medicare, the drugmaker said. Patients will be able to purchase any combination, type, and quantity of Sanofi insulins with a valid prescription for the fixed monthly price of $35, starting January 1. Lilly and Novo also have similar programs through which they offer insulin products for $35 a month for U.S. patients regardless of whether the patients have insurance. There is no law at work here – the only legislation that has changed the price of insulin came with the Inflation Reduction Act in 2022 with the Medicare cap. Helping lower the cost here, biosimilars hitting the market and the huge profitability for GLP-1 drugs for Novo and Lilly https://www.reuters.com/business/healthcare-pharmaceuticals/sanofi-offer-all-insulin-products-35-per-month-us-2025-09-26/ XX A pill typically prescribed for rheumatoid arthritis and alopecia might help slow the progression of type 1 diabetes, a new study says. Baricitinib (bare-uh-SIT-nib) safely preserved the body's own insulin production in people newly diagnosed with type 1 diabetes.. and their diabetes started progressing once they stopped taking baricitinib, results show. They produced less insulin and had less stable blood sugar levels.   Baricitinib works by quelling signals in the body that spur on the immune system, and is already approved for treating autoimmune conditions such as rheumatoid arthritis, ulcerative colitis and alopecia, researchers said.   “Among the promising agents shown to preserve beta cell function in type 1 diabetes, baricitinib stands out because it can be taken orally, is well tolerated, including by young children, and is clearly efficacious,” Waibel said. “We are hopeful that larger phase III trials with baricitinib are going to commence soon, in people with recently diagnosed type 1 diabetes as well as in earlier stages to delay insulin dependence,” she added. “If these trials are successful, the drug could be approved for type 1 diabetes treatment within five years.”   Findings presented at medical meetings should be considered preliminary until published in a peer-reviewed journal.   https://www.usnews.com/news/health-news/articles/2025-09-23/pill-effective-in-slowing-type-1-diabetes-progression XX An existing transplant drug has shown promise in slowing the progression of type 1 diabetes in newly diagnosed young people, potentially paving the way for the first therapy that modifies the disease after diagnosis. The Drug, called ATG, is currently used together with other medicines to prevent and treat the body from rejecting a kidney transplant. It can also be used to treat rejection following transplantation of other organs, such as hearts, gastrointestinal organs, or lungs. The researchers studied 117 people aged five to 25, who'd been diagnosed with type 1 diabetes within the past three to nine weeks. The participants were from 14 centers across eight European countries and were randomized to be given different doses of ATG (0.1, 0.5, 1.5, or 2.5 mg/kg) or a placebo. ATG was given as a two-day intravenous (IV) infusion. The main goal was to see how well the pancreas could still make insulin after 12 months, measured by C-peptide levels during a special meal test. C-peptide is released into the blood along with insulin by the pancreas.   The findings are promising, showing that ATG, even at a relatively low dose, can slow the loss of insulin-producing cells in young people newly diagnosed with type 1 diabetes. The lower dose also caused fewer side effects, making it a more practical option. https://newatlas.com/disease/antithymocyte-globulin-newly-diagnosed-type-1-diabetes/     XX The FDA has delayed its feedback on Lexicon Pharmaceuticals' application to bring Zynquista (sotagliflozin) to people with type 1 diabetes. The agency had planned to respond this month but will now wait until the fourth quarter after reviewing new data from ongoing studies. Zynquista, an oral drug meant to be used with insulin, has already been approved for heart failure (marketed as Inpefa). But in type 1 diabetes, it faces safety concerns: last year an FDA advisory committee voted 11–3 that its benefits don't outweigh the increased risk of diabetic ketoacidosis (DKA). The FDA later issued a complete response letter rejecting the drug. Lexicon is still pushing forward, hoping its additional submissions will strengthen Zynquista's case for type 1 diabetes approval. https://www.biospace.com/fda/after-fda-rejection-lexicons-type-1-diabetes-drug-hit-with-another-regulatory-delay     XX A common but often undiagnosed genetic condition may be causing delays in type 2 diabetes diagnoses and increasing the risk of serious complications for thousands of Black and South Asian men in the UK—and potentially millions worldwide. A new study found around one in seven Black and one in 63 South Asian men in the UK carry a genetic variant known as G6PD deficiency. Men with G6PD deficiency are, on average, diagnosed with type 2 diabetes four years later than those without the gene variant. But despite this, fewer than one in 50 have been diagnosed with the condition.   G6PD deficiency does not cause diabetes, but it makes the widely used HbA1c blood test—which diagnoses and monitors diabetes—appear artificially low. This can mislead doctors and patients, resulting in delayed diabetes diagnosis and treatment.   The study found men with G6PD deficiency are at a 37% higher risk of developing diabetes-related microvascular complications, such as eye, kidney, and nerve damage, compared to other men with diabetes.   "This study highlights important evidence that must be used to tackle these health inequalities and improve outcomes for Black communities. Preventative measures are now needed to ensure that Black people, especially men, are not underdiagnosed or diagnosed too late." https://medicalxpress.com/news/2025-09-hidden-genetic-delay-diabetes-diagnosis.html XX Novo Nordisk today announced the resubmission of its Biologics License Application (BLA) to the US Food and Drug Administration (FDA) for Awiqli® (insulin icodec) injection, a once-weekly basal insulin treatment for adults living with type 2 diabetes. If approved, Awiqli® would become the first once-weekly basal insulin available in the United States, providing an alternative to daily basal insulin injections for adults living with type 2 diabetes.   The resubmission is based on results from the ONWARDS type 2 diabetes phase 3a program for once-weekly Awiqli® which is comprised of five randomized, active-controlled, treat-to-target clinical trials in approximately 4,000 adults with type 2 diabetes. The clinical program evaluated Awiqli® vs. daily basal insulin and the primary endpoint in these trials was change in A1C from baseline.1-5 Awiqli® is approved in the EU, along with 12 additional countries. In addition, regulatory filings have been completed in several other countries, with further regulatory decisions expected in 2025. XX Interesting news from Sequel Med Tech – they've signed an agreement with Arecor to pair the twiist pump with AT278 an ultra-concentrated (500U/mL), ultra-rapid insulin in development. They also have a deal with Medtronic to develop insulin for new pumps. This insulin isn't yet approved, it's 5 times stronger than standard fast acting  it's hoped that a clinical study will begin next year. Arecor says its insulin could potentially be the only option capable of enabling and catalyzing the next generation of longer-wear and miniaturized automated insulin delivery systems.   https://www.drugdeliverybusiness.com/sequel-arecor-develop-rapid-insulin-twiist/ XX Tandem Diabetes Care announes its t:slim X2™ insulin pump with Control-IQ+ automated insulin delivery (AID) technology is now cleared for use with Eli Lilly and Company's Lyumjev® (insulin lispro-aabc injection) ultra-rapid acting insulin in the United States (U.S.).   – The t:slim X2 insulin pump with Control-IQ+ technology is now cleared for use with Lyumjev for people with type 1 diabetes ages 2 and above and all adults with type 2 diabetes. The companies are continuing to work toward securing Lyumjev compatibility for the Tandem Mobi pump. https://hitconsultant.net/2025/09/29/tandem-diabetes-cares-tslim-x2-pump-cleared-for-use-with-lillys-ultra-rapid-lyumjev-insulin/ XX You can now place your order for the MiniMed™ 780G system with the Instinct sensor, made by Abbott. And if you are already a MiniMed 780G user, you can place an upgrade order today. ​This is a 15 day wear sensor, with no transmitter or overtape required. It looks the same at other Abbot sensors such as the Libre but is proprietary to Medtronic. Shipments are scheduled to start in November.   ​ https://www.drugdeliverybusiness.com/medtronic-launches-minimed-780g-instinct-abbott/   XX The global type 1 diabetes (T1D) burden continues to increase rapidly driven by rising cases, ageing populations, improved diagnosis and falling death rates. ,   The study estimates that T1D will affect 9.5 million people globally in 2025 (up by 13% since 2021), and this number is predicted to rise to 14.7 million in 2040. However, due to lack of diagnosis and challenges in collecting sufficient data, the actual number of individuals living with T1D is likely much higher, researchers say.   In fact, they estimate that there are an additional 4.1 million 'missing people' who would have been alive in 2025 if they hadn't died prematurely from poor T1D care, including an estimated 669,000 who were not diagnosed. This is particularly true in India, where an estimated 159,000 people thought to have died from missed diagnoses. The study predicts that 513,000 new cases of T1D will be diagnosed worldwide in 2025, of which 43% (222,000) will be people younger than 20 years old. Finland is projected to have the highest incidence of T1D in children aged 0-14 years in 2025 at around 64 cases per 100,000. The substantial increases in T1D forecasts between 2025 and 2040 underscore the urgent need for action. As co-author Renza Scibilia from Breakthrough T1D explains, "Early diagnosis, access to insulin and diabetes supplies, and proper healthcare can bring enormous benefits, with the potential to save millions of lives in the coming decades by ensuring universal access to insulin and improving the rate of diagnosis in all countries."   The authors note some important limitations to their estimates, including that while the analysis uses the best available data, predictions are constrained by the lack of accurate data in most countries-highlighting the urgent need for increased surveillance and research. They also note that data on misdiagnosis and adult populations remain limited, and the analysis assumes constant age-specific incidence and mortality over time. Furthermore, incidence data from the COVID-19 period were excluded from part of the modelling to avoid bias. Future updates are expected to improve as new data become available and applied. https://www.news-medical.net/news/20250919/New-study-warns-of-millions-of-undiagnosed-and-missing-people-with-type-1-diabetes.aspx XX A new study has found that semaglutide — the active ingredient found in some GLP-1 medications prescribed for diabetes and to aid weight loss — may help protect the eyes from diabetic retinopathy. Researchers estimate that as much as 40% of all people with diabetes also have diabetic retinopathy — a potentially blinding eye condition caused by blood vessel damage in the eye's retina. There is currently no cure for diabetic retinopathy. The condition is often managed through injections of anti-VEGF medications into the eye, surgery, and blood sugar monitoring and control. For this lab-based study, researchers used samples of human retinal endothelial cells that were treated with different concentrations of semaglutide. The cells were then placed in a solution with both a high glucose level and high level of oxidative stress — where there is an imbalance of antioxidants and free radicals — for 24 hours.   Past studies show that oxidative stress plays a role in the formation of diabetic retinopathy.   At the study's conclusion, researchers found that the retinal cells treated with semaglutide were twice as likely to survive than cells that were untreated. Additionally, the treated cells were found to have larger stores of energy.   Scientists also found that three markers of diabetic retinopathy were decreased in the semaglutide-treated retinal cells. First, the levels of apoptosis — a form of cell death — decreased from about 50% in untreated cells to about 10% in semaglutide-treated cells. The production of the free radical mitochondrial superoxide decreased from about 90% to about 10% in the treated retinal cells.   Researchers also found the amount of advanced glycation end-products — harmful compounds that can collect in people with diabetes and are known to cause oxidative stress — also decreased substantially.   Lastly, scientists reported that the genes involved in the production of antioxidants were more active in the semaglutide-treated cells when compared to untreated cells. Researchers believe this is a sign that semaglutide may help repair damage to the retinal cells.   “Our study did not find that these drugs harmed the retinal cells in any way — instead, it suggests that GLP1-receptor agonists protect against diabetic retinopathy, particularly in the early stages,” Ioanna Anastasiou, PhD, molecular biologist and postdoctoral researcher at the National and Kapodistrian University in Greece, and lead author of this study, said in a press release.   “Excitingly, these drugs may be able to repair damage that has already been done and so improve sight. Clinical trials are now needed to confirm these protective effects in patients and explore whether GLP-1 receptor agonists can slow, or even halt, the progression of this vision-robbing condition.” https://www.medicalnewstoday.com/articles/ozempic-semaglutide-may-help-protect-against-diabetes-related-blindness-retinopathy   XX Biolinq has received De Novo Classification from the U.S. Food and Drug Administration for its lead product, Biolinq Shine, a patch on the forearm that provides real-time glucose feedback through a primary color-coded LED display, visible with or without a phone. This one is tricky – it's called a needle free CGM but it also says it uses micro needles. By the way, De Novo isn't exactly the same as what we think of for FDA approval for medical devices. It's not as rigorous but it's a streamlined route for novel, low to moderate risk devices with no existing equivalent. We'll see how this one turns out. https://www.hmenews.com/article/biolinq-s-multi-function-biosensor-receives-fda-de-novo-classification

In this episode of the Heart to Heart podcast, host Dr.Mike Hart welcomes author Serena Choo, who delves into her journey of writing and overcoming imposter syndrome. They discuss Serena's second book, 'The Monkey and the Way of Zen,' which contains 28 short Zen-inspired stories aimed at providing readers a relaxing and reflective experience. Choo shares insights into the origins of her work, the importance of letting go and subtracting complexities from life, and how personal transformation can be achieved without the burden of constant goal-setting. Additionally, they touch upon topics such as her career transition, the specifics of dealing with imposter syndrome, the concept of emotional intelligence, and the potential benefits of neurolinguistic programming (NLP).   Serena Choo is a transformation coach, author, and thought leader in personal growth and self-discovery. With over two decades of experience spanning corporate finance, executive coaching, and nutritional therapy, Serena has dedicated her career to helping people break free from self-doubt, imposter syndrome, and burnout. She is the author of Letting Go of Imposter Syndrome and The Monkey and the Way of Zen: A Transformation Journey in 28 Short Stories, books that blend practical wisdom with storytelling to inspire reflection, inner peace, and authentic living. Drawing from her background in executive coaching, functional medicine, and NLP, Serena's work emphasizes radical surrender, self-awareness, and creating fulfillment through subtraction rather than constant striving. Learn more about Serena at serenachoo.com Books available on Amazon: Letting Go of Imposter Syndrome and The Monkey and the Way of Zen   Links: Stanford Encyclopedia of Philosophy – Stoicism NLP Association Functional Medicine Coaching Academy Show Notes: 00:00 Welcome back to the Hart2Heart Podcast with Dr. Mike Hart 00:30 Discussing Serena's books 02:00 The inspiration behind 'the monkey and the zen' 02:00 Serena's writing journey 04:30 Finding nemo and storytelling 05:30 The essence of zen stories 06:00 Mike's reflection on reading 07:30 Goal setting and personal fulfillment 08:30 Serena's career background 10:00 Transition to coaching 17:00 Imposter syndrome explained 21:30 Techniques to overcome imposter syndrome 27:30 Changing thought patterns 31:30 The role of fortune and stoicism 33:30 Imposter syndrome and self-doubt 34:00 Personal anecdotes and overcoming challenges 38:00 Accepting compliments and authenticity 48:30 Emotional intelligence and reactions 48:50 “To me, emotional intelligence is first about understanding what's going on within yourself — not pushing away the feelings, but being aware of the programs running underneath.” 55:30 Coaching differences between genders 01:00:30 NLP and its benefits   — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  Policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

In this episode of Healthy Waves by Healthy Mind By Avik™, host Avik Chakraborty sits down with David Hunter, founder of Global Phytoplankton Alliance, to uncover the untapped potential of marine phytoplankton for human health, brain function, and sustainability. David shares how a microscopic ocean plant, often invisible to the naked eye, may hold the foundation for human vitality—supporting cellular repair, energy, and even mental clarity. With nearly 20 years of experience, he discusses the surprising history of phytoplankton in nutrition, how it contributes to Earth's oxygen supply, and why it might reshape the way we think about supplements, immunity, and disease prevention. Whether you're curious about brain health, natural nutrition, or the future of sustainable wellness, this conversation offers insights you won't want to miss. About the Guest  : David Hunter is the founder of Global Phytoplankton Alliance. Nearly two decades ago, he witnessed phytoplankton transform a life when nothing else worked. Since then, he has dedicated himself to educating the world on how these microscopic organisms—responsible for much of Earth's oxygen—could be the missing link in human health, foundational nutrition, and planetary sustainability. Key Takeaways:   Medical Disclaimer  : The content in this episode and its accompanying show notes is for educational and informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition, nutrition, or supplementation—including marine phytoplankton or any nutraceuticals. Never disregard professional medical advice or delay seeking it because of something you heard in this episode. Statements discussed here (including any potential benefits of phytoplankton) have not been evaluated by the U.S. Food and Drug Administration (FDA), European Medicines Agency (EMA), or any other regulatory authority. These products are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. If you are pregnant, nursing, have a medical condition, or are taking prescription or over-the-counter medications, consult your healthcare professional before using any supplement. Discontinue use and consult a healthcare professional if you experience any adverse reaction. In case of a medical emergency, call your local emergency number immediately. All opinions expressed by the guest are their own and do not represent the views of the host or Healthy Mind By Avik™.   Phytoplankton is the original source of nutrition, containing essential fatty acids, vitamins, minerals, and antioxidants in their purest form. Marine phytoplankton provides 60–75% of the oxygen we breathe, making it critical for planetary and human health. Unlike synthetic supplements, phytoplankton nutrients bypass digestion and may feed directly into human cells. Stories of improved energy, mental clarity, reduced migraines, and other benefits highlight its potential role in foundational wellness. Growing phytoplankton on land in clean, filtered seawater avoids ocean depletion and provides a sustainable nutrient source. Its potential impact could disrupt the supplement industry and support a healthier, more resilient global population. Preventive health—focusing on nourishment before illness—can reduce dependency on reactionary treatments. The future of wellness may be less about "bigger solutions" and more about microscopic foundations. Connect with the Guest   Website: USAGPA.com – Global Phytoplankton Alliance Want to be a guest on Healthy Mind, Healthy Life?   DM on PM – Send me a message on PodMatch DM Me Here: https://www.podmatch.com/hostdetailpreview/avik Disclaimer   This video is for educational and informational purposes only. The views expressed are the personal opinions of the guest and do not reflect the views of the host or Healthy Mind By Avik™️. We do not intend to harm, defame, or discredit any person, organization, brand, product, country, or profession mentioned. All third-party media used remain the property of their respective owners and are used under fair use for informational purposes. By watching, you acknowledge and accept this disclaimer. About Healthy Mind By Avik™️   Healthy Mind By Avik™️ is a global platform redefining mental health as a necessity, not a luxury. Born during the pandemic, it has become a sanctuary for healing, growth, and mindful living. Hosted by Avik Chakraborty—storyteller, survivor, and wellness advocate—this channel shares powerful podcasts and soul-nurturing conversations on:• Mental Health & Emotional Well-being• Mindfulness & Spiritual Growth• Holistic Healing & Conscious Living• Trauma Recovery & Self-Empowerment With over 4,400+ episodes and 168.4K+ global listeners, join us as we unite voices, break stigma, and build a world where every story matters.

On this Healthy Waves episode, host Avik digs into how aerospace-level problem-solving meets wellness tech. Guest Mark Fox (former Space Shuttle chief engineer, hot-air balloonist, and airplane builder) explains why he shifted from aircraft to energy-based wellness devices. We unpack what pulsed electromagnetic field (PEMF) and resonance-frequency approaches claim to do, how protocols are designed, portability and cost tradeoffs vs. legacy gear, and where AI-driven biometrics might steer the next decade. Direct, no fluff—just a clear look at what this tech promises, what users report, and what still needs rigorous proof for platforms like YouTube, Facebook, Instagram, and LinkedIn. About the guest  : Mark Fox is an aerospace engineer turned wellness tech founder at Resona Health (resona.health). Drawing on systems thinking (including TRIZ creative problem-solving), he designs portable, non-invasive devices intended to support general well-being through frequency-based protocols. Key takeaways: Why the pivot: engineering skills can transfer from avionics to wellness when the goal is simpler, more accessible tools for everyday use. Frequency-based view: the talk frames the body as chemical, mechanical, and electrical—arguing wellness tools shouldn't ignore bio-electromagnetic processes. How protocols are built: “frequency pairs” change over time like chords in a song; many protocols emerged from decades of practitioner iteration. Portability and access: a pocket device aims to make sessions simpler and more affordable than clinic-only mats or large systems. Reported use cases: the guest discusses user-reported improvements in stress, HRV, sleep, pain, and more—presented as claims and ongoing studies, not medical advice. Safety framing: energy level and frequency matter; the device output described is far below MRI fields, though MRI safety analogies should not be read as equivalence in efficacy. AI + biometrics: future direction includes watches, cloud trends, and automated recommendations—raising opportunities and the need for privacy and validation. Bottom line: intriguing engineering applied to wellness; further independent, peer-reviewed evidence is essential before making health decisions. Medical Disclaimer This content is for educational and informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of your physician or other qualified health provider with any questions you may have regarding a medical condition, symptoms, or health objectives. Never disregard professional medical advice or delay seeking it because of something you heard in this episode or read in the show notes. Any products, devices, protocols, or practices discussed are presented as general wellness information only. They are not intended to diagnose, treat, cure, or prevent any disease. Statements made by guests are their personal opinions and experiences and have not been evaluated by the U.S. Food and Drug Administration (FDA) or other regulatory authorities. Results vary from person to person. If you are experiencing a medical emergency or mental health crisis, call your local emergency number immediately or contact your nearest crisis hotline. How to connect with the guest   Website: https://resona.health/ Email: info@resona.health Want to be a guest on Healthy Mind, Healthy Life? DM on PM - Send me a message on PodMatch DM Me Here: https://www.podmatch.com/hostdetailpreview/avik   Disclaimer: This video is for educational and informational purposes only. The views expressed are the personal opinions of the guest and do not reflect the views of the host or Healthy Mind By Avik™️. We do not intend to harm, defame, or discredit any person, organization, brand, product, country, or profession mentioned. All third-party media used remain the property of their respective owners and are used under fair use for informational purposes. By watching, you acknowledge and accept this disclaimer.   Healthy Mind By Avik™️ is a global platform redefining mental health as a necessity, not a luxury. Born during the pandemic, it's become a sanctuary for healing, growth, and mindful living. Hosted by Avik Chakraborty—storyteller, survivor, wellness advocate—this channel shares powerful podcasts and soul-nurturing conversations on: • Mental Health & Emotional Well-being• Mindfulness & Spiritual Growth• Holistic Healing & Conscious Living• Trauma Recovery & Self-Empowerment With over 4,400+ episodes and 168.4K+ global listeners, join us as we unite voices, break stigma, and build a world where every story matters.

The U.S. Food and Drug Administration (FDA) has now launched a safety label change warning of the dangers of Tylenol in pregnant mothers. The FDA also announced approval of leucovorin, a form of folic acid suggested as a treatment for autism symptoms. The medical community, in collusion with public health officials, has long pointed to a ‘blame-the-victim' approach, saying it was just children with unlucky genetics – a nod to eugenics musings and insulting to families looking for answers.

  In this episode of The Heart to Heart podcast, host Dr. Mike Hart interviews Alex Leaf, an independent nutritional researcher renowned for debunking nutritional misinformation on social media. The discussion covers topics such as the benefits of collagen for skin health, the potential advantages of ketogenic diets for athletes, and the truth behind various nutrition myths including the effects of soy on testosterone and semen retention. Alex also shares his insights on intermittent fasting, ideal protein intake, and the debate over seed oils. The conversation concludes with their thoughts on cardiovascular health markers and the relevance of particle size in LDL cholesterol.    Alex Leaf is an independent nutritional researcher, scientific communicator, and educator specializing in human health and performance. With a decade of experience translating complex science into actionable insights, Alex rose to prominence as a researcher and writer at Examine.com before joining Ari Whitten's Energy Blueprint. His work spans peer-reviewed publications—including contributions to the ISSN position stand on ketogenic diets—and teaching in the Master's program in Human Nutrition and Functional Medicine at the University of Western States. Follow him here: Website: alexleaf.com Instagram: @AlexJLeaf   Links: IVF and Abstinence Studies Systematic Review on Ketogenic Diets in Athletes Whey Protein vs. Beef Protein Show Notes: 00:00 – Welcome back to the Hart2Heart Podcast with Dr. Mike Hart 02:30 – Collagen and skin health 08:30 – Ketogenic diets for athletes 14:00 – Protein intake for athletes 18:00 – Intermittent fasting vs caloric restriction 25:00 – Seed oils: myths and facts 30:00 – Semen retention: debunking the myths 35:00 – Soy and hormones 38:30 – Soy consumption and hormonal effects 39:30 – Whey protein: benefits and misconceptions 42:30 – Post-workout nutrition myths 45:00 – Insulin sensitivity and carbohydrate timing 54:00 – Protein intake strategies 57:00 – Calories and diet composition 57:14 – “A calorie is a calorie, but depending on your diet's composition, you'll absorb and utilize very different amounts of calories from food.” 01:01:00 – Debating dietary approaches 01:05:00 – Cardiovascular health markers 01:12:00 – Conclusion and contact information   — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  Policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

On Monday, President Donald Trump, Department of Health and Human Services (HHS) Secretary Robert F. Kennedy Jr., and other Trump administration officials announced a pair of actions the Food and Drug Administration (FDA) will take to address the increase in autism spectrum disorder (ASD) in children. First, the FDA will update the warning labels for acetaminophen — the active ingredient in pain relievers like Tylenol — to note a potential association between the ingredient and neurological conditions — such as ASD and attention-deficit/hyperactivity disorder (ADHD) — in children (though it also emphasized that no causal link has been established). Second, the agency has initiated the approval of leucovorin calcium tablets for patients with cerebral folate deficiency (CFD). Ad-free podcasts are here!To listen to this podcast ad-free, and to enjoy our subscriber only premium content, go to ReadTangle.com to sign up!You can read today's podcast⁠ ⁠⁠here⁠⁠⁠, our “Under the Radar” story ⁠here and today's “Have a nice day” story ⁠here⁠.You can subscribe to Tangle by clicking here or drop something in our tip jar by clicking here. Take the survey: What do you think about the HHS announcement, autism, and Tylenol? Let us know.Disagree? That's okay. My opinion is just one of many. Write in and let us know why, and we'll consider publishing your feedback.Our Executive Editor and Founder is Isaac Saul. Our Executive Producer is Jon Lall.This podcast was written by Ari Weitzman and edited and engineered by Dewey Thomas. Music for the podcast was produced by Diet 75.Our newsletter is edited by Managing Editor Ari Weitzman, Senior Editor Will Kaback, Lindsey Knuth, Kendall White, Bailey Saul, and Audrey Moorehead. Hosted on Acast. See acast.com/privacy for more information.

The latest episode of the DDW Highlights Podcast is now available to listen to below. DDW's Bruno Quinney narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. In this week's news, AstraZeneca has halted its £200 million research investment in the UK. Elsewhere, the US Food and Drug Administration (FDA) has fast-tracked a gene therapy, CAR-T therapy could be an effective cancer treatment, and the National Institute for Health and Care Excellence (NICE) has updated its thresholds for ultra-rare disease drugs. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

In this episode of The Heart to Heart podcast, host Dr. Mike Hart welcomes back Rav, an author and host of the Illusion of Consensus podcast. The conversation delves into Rav's evolving interests, from his initial focus on COVID-19 and myocarditis to his current pursuit of a more holistic and spiritually grounded life. Rav discusses his journey through rigorous psychotherapy, aided by psychedelics, to uncover subconscious patterns and improve his overall well-being. The discussion also touches on the utility of AI tools like ChatGPT as supplementary therapy, the impact of social media on Gen Z's social behaviors, and the rising influence of independent journalism. The episode sheds light on finding balance in a hyper-productive world, integrating different therapeutic pathways, and the significance of peaceful presence in one's life. Rav Arora is an independent journalist, cultural critic, and podcast host exploring the intersections of health, spirituality, and human performance. Rising to prominence through his widely read Substack, The Meta Mystic, and as co-host of The Illusion of Consensus podcast, Rav has become a leading voice challenging mainstream narratives in science, psychology, and culture. Follow him here: Substack: The Meta MysticPodcast: The Illusion of ConsensusTwitter/X: @Ravarora1 Links: Psilocybin & Religious Leaders Study Internal Family Systems (IFS) Pain Reprocessing Therapy (PRT) Show Notes: (00:00)Welcome back to the Hart2Heart Podcast with Dr. Mike Hart (01:00) Shifting gears: From COVID to holistic living (02:30) The role of psychedelics in therapy (04:00) Balancing productivity and relaxation (10:00) ChatGPT as a therapeutic tool (18:30) Exploring psychedelic therapy (28:00) The power of peaceful presence (39:00) Psilocybin study on religious leaders (40:30) Challenges in recruiting for the study (41:00) Gen Z and alcohol consumption (42:30) Impact of social media on social skills (43:00) Dating apps and their consequences (50:48) “Social media has provided this illusion and comfort.” (53:30) Independent journalism's rise (01:00:30) The future of media and podcasting   — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

The U.S. Food and Drug Administration (FDA) launched an investigation after shrimp bound for Walmart tested positive for a man-made radioactive substance.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Question: When should relevant documentation submitted to a regulatory review body be submitted for the Office for review? Answer: Where relevant documentation is submitted to a regulatory review body, such as the U.S. Food & Drug Administration (FDA), and is material to any pending patent application or reexamination proceeding, such documentation should be submitted for […] The post MPEP Q & A 336: Circumstances when relevant documentation should be submitted to regulatory review body. appeared first on Patent Education Series.

In this solo podcast episode, Dr Mike Hart provides actionable, evidence-backed strategies to improve overall circadian rhythm and consequently enhance sleep quality. He discusses the importance of a regulated sleep-wake cycle and its impact on hormone release, metabolism, immune function, and general well-being. Various methods to maintain a healthy circadian rhythm are explored, including the benefits of morning sunlight exposure, the role of blue light blocking in the evening, and the timing of meals and exercise. He also touches on the effects of caffeine and alcohol on sleep, the ideal sleep environment, and additional supportive practices like social interaction, light physical activity, and evening routines that promote relaxation.   Links: Dual Orexin Receptor Antagonists (DORAs) Forgiveness & Better Sleep (PubMed) Omega-3 (Fish Oil / EPA)   Show Notes: (0:00) Welcome back to the Hart2Heart Podcast with Dr. Mike Hart (01:30) Natural sleep improvement tips (02:33)  "Cortisol isn't bad—it's about timing. You want it high in the morning and low at night for better sleep." (04:30) Behavioral modifications and supplements (08:30) Introduction to prescription sleep medications (10:00) Dual orexin receptor antagonists (DORAs) (14:30) Z-Drugs: Benefits and risks (18:00) Benzodiazepines: Usage and caution (20:30) Doxepin and H1 inverse agonists (22:30) Gabapentinoids for sleep and pain (26:30) Alpha adrenergic agents (31:30) Sedating antidepressants (37:30) Sodium oxybate for narcolepsy — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

Multitasking feels productive but it's actually draining your energy. I share what happened when I spent a full day doing one thing at a time, how it impacted my stress and focus, and why single-tasking can help you feel calmer and more energized in perimenopause. Hey Hormone Hotties:If you want to learn more about how you can work with me or what services I offer including those below- https://linktr.ee/TheHappyHormonesCoach Interested in being a guest expert (even if you are not in business but a woman who has a story to share) fill out the application and book an appointment. Affiliated Partner for awesome products in wellness and more including the "Body balancing" slenderize for a discount using my code HAPPY24 Join me in Happy Hormones Circle. This and my email list is where I will be focusing my time and content Disclaimer: The content shared in ‘The Happy Hormones Coach' podcast (including affiliate and non affiliate products) is for informational purposes only and is not intended as medical advice, diagnosis, or treatment. Please consult with a qualified healthcare provider before making any changes to your diet, exercise, or health routine. The opinions expressed in this podcast are those of the host and guests and do not necessarily reflect the views of any healthcare organizations. The statements made regarding any of the products that I mention have not been evaluated by the Food and Drug Administration (FDA). Individual results may vary.

 One day, I closed my planner, walked away from my list, and let my energy lead the way. In this episode, I share why ignoring my to-do list lowered my stress, improved my focus, and reminded me that rest is a productive choice  especially in perimenopause. Hey Hormone Hotties:If you want to learn more about how you can work with me or what services I offer including those below- https://linktr.ee/TheHappyHormonesCoach Interested in being a guest expert (even if you are not in business but a woman who has a story to share) fill out the application and book an appointment. Affiliated Partner for awesome products in wellness and more including the "Body balancing" slenderize for a discount using my code HAPPY24 Join me in Happy Hormones Circle. This and my email list is where I will be focusing my time and content Disclaimer: The content shared in ‘The Happy Hormones Coach' podcast (including affiliate and non affiliate products) is for informational purposes only and is not intended as medical advice, diagnosis, or treatment. Please consult with a qualified healthcare provider before making any changes to your diet, exercise, or health routine. The opinions expressed in this podcast are those of the host and guests and do not necessarily reflect the views of any healthcare organizations. The statements made regarding any of the products that I mention have not been evaluated by the Food and Drug Administration (FDA). Individual results may vary.

In this episode of the Heart to Heart podcast, Dr. Mike Hart hosts Dr. Chester Sokolowski, a peptide expert and the founder of Thrive Telehealth Clinic, which specializes in hormone replacement therapy (HRT) and peptide treatments for both men and women. Dr. Sokolowski discusses his background, career, and various business ventures focused on human performance and optimization. The conversation delves deep into the benefits and applications of testosterone replacement therapy (TRT), peptides, and other health-related topics. Key points include the implications of TRT, managing estrogen levels, the benefits of combining peptides for muscle growth and recovery, and the groundbreaking potential of GLP-1 agonists like Ozempic and Retatrutide for weight loss and metabolic health. Dr. Sokolowski also touches on the benefits of glutathione, the latest research on peptides such as BPC-157 and TB-500, and the ethical considerations of using these therapies in professional sports. Dr. Chester Sokolowski is a performance optimization expert, telehealth clinician, and leading voice in hormone and peptide therapy. He earned his doctoral training at Florida State University and has dedicated his career to human performance, healthspan, and longevity. Known online as “Dr. Soko”, he shares cutting-edge insights on testosterone therapy, peptides, recovery, and performance through social media and educational content. His work empowers people to look, feel, and perform at their absolute best. Follow him on Instagram: @dr.soko, LinkedIn: Dr. Chester Sokolowski and YouTube: Dr. Soko Links: TRT (Testosterone Replacement Therapy) Ozempic (Semaglutide) DIM (Diindolylmethane) Oxidative stress & disease   Show Notes: (00:00) Introduction to the Heart to Heart Podcast (02:30) Dr. soko's dissertation on binge drinking and muscle growth (06:00) Cold therapy and hypertrophy (08:00) TRT and arimidex discussion (13:35) “Estrogen is not the enemy; it's actually protective for your heart, your brain, your joints.” (14:30) HCG and fertility (20:00) Peptides and GLP-1 drugs (34:30) Minimizing side effects and dosage strategies (35:30) Understanding GLP-1 mechanisms (36:00) Red aide: the unique GLP-1 (39:00) Visceral fat and GLP-1 effectiveness (41:00) GLP-1s and impulse control (46:30) Glutathione: the ultimate antioxidant (50:30) Peptides for skin and hair health (51:00) Growth hormone peptides: which is best? (55:00) BPC-157 and tb-500: healing peptides (01:00:30) TRT, peptides, and sports (01:03:00) Conclusion and contact information   — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

 Your grocery cart tells a story about your priorities, your season of life, and your health goals. I'm taking you inside my own cart, guilty pleasures and all, to show you how to shop for hormone health without giving up balance, joy, or flavor. Hey Hormone Hotties:If you want to learn more about how you can work with me or what services I offer including those below- https://linktr.ee/TheHappyHormonesCoach Interested in being a guest expert (even if you are not in business but a woman who has a story to share) fill out the application and book an appointment. Affiliated Partner for awesome products in wellness and more including the "Body balancing" slenderize for a discount using my code HAPPY24 Join me in Happy Hormones Circle. This and my email list is where I will be focusing my time and content Disclaimer: The content shared in ‘The Happy Hormones Coach' podcast (including affiliate and non affiliate products) is for informational purposes only and is not intended as medical advice, diagnosis, or treatment. Please consult with a qualified healthcare provider before making any changes to your diet, exercise, or health routine. The opinions expressed in this podcast are those of the host and guests and do not necessarily reflect the views of any healthcare organizations. The statements made regarding any of the products that I mention have not been evaluated by the Food and Drug Administration (FDA). Individual results may vary.

May 22nd is the National Day of Prayer and Remembrance for Mariners and Seafarers. Bishop Brendan Cahill discusses the ministry of the church to seafarers through the work of Stella Maris. The day is intended to remember the men and women seafarers. Many seafarers are Catholic Christians and largely a migrant population in the world. Because of the nature of their work, they are not always a visible community presence. In over 50 ports, there are more than 100 Stella Maris chaplains, maritime deacons, and lay ecclesial ministers who minister to seafarers. They welcome, network, and reach out to seafarers, fishermen and women, their families, and all who work or travel on the seas. Through the celebration of the Eucharist and the Word of God, the chaplaincy team helps seafarers discover the loving presence of God in an often-challenging world. Their continued presence is a clear indication of their dedication to this vital pastoral ministry and love for the people of the sea. https://www.usccb.org/committees/pastoral-care-migrants-refugees-travelers/stella-maris-who-we-are On Wednesday, May 10, a panel of advisors to the U.S. Food and Drug Administration (FDA) voted unanimously to make the birth-control drug, Opill, available to consumers over-the-counter in the United States. The FDA is reportedly poised to make a final decision this summer. In response to the FDA panel's recommendation, Bishop Robert E. Barron of Winona-Rochester, and chairman of the U.S. Conference of Catholic Bishops' (USCCB) Committee on Laity, Marriage, Family Life and Youth, urged the government agency to reject this advice as “not good medicine” and continue their efforts to protect women's health. Read the full statement. https://www.usccb.org/news/2023/fda-acknowledges-harm-oral-contraceptives-while-its-own-panel-advisors-push-make-drug After literally hundreds of public prayers for peace in Ukraine and 443 days after Russia launched an all-out war on the Eastern European country, Pope Francis welcomed Ukrainian President Volodymyr Zelenskyy to the Vatican. This was their first face-to-face meeting since the war began. Read the Catholic News Service Rome story. https://www.usccb.org/news/2023/pope-ukrainian-leader-talk-about-humanitarian-situation-provoked-war

 Sometimes the healthiest choice is breaking your own “perfect” routine. In this episode, I share what happened when I swapped my strict morning plan for what my body actually needed and why that flexibility can be a game-changer for your hormones, stress, and energy in perimenopause. Hey Hormone Hotties:If you want to learn more about how you can work with me or what services I offer including those below- https://linktr.ee/TheHappyHormonesCoach Interested in being a guest expert (even if you are not in business but a woman who has a story to share) fill out the application and book an appointment. Affiliated Partner for awesome products in wellness and more including the "Body balancing" slenderize for a discount using my code HAPPY24 Join me in Happy Hormones Circle. This and my email list is where I will be focusing my time and content Disclaimer: The content shared in ‘The Happy Hormones Coach' podcast (including affiliate and non affiliate products) is for informational purposes only and is not intended as medical advice, diagnosis, or treatment. Please consult with a qualified healthcare provider before making any changes to your diet, exercise, or health routine. The opinions expressed in this podcast are those of the host and guests and do not necessarily reflect the views of any healthcare organizations. The statements made regarding any of the products that I mention have not been evaluated by the Food and Drug Administration (FDA). Individual results may vary.

What does “great” Medical Affairs look like in 2025? We talk evidence, access, patient voice, and how to work with Commercial without crossing the promotional line. Abdul Hameed Al-Khateeb, Country Medical Director, shares practical lessons on measurement, real-world evidence, and where AI actually helps.Email to your listSubject line options (pick one):Inside Medical Affairs: From Evidence to AccessThe Missing Link Between Science and PatientsWhat Great Medical Affairs Looks Like (and How to Measure It)

 If your energy swings between “I can conquer the world” and “I need a nap now,” you're not alone — and you're not broken. In this episode of The Happy Hormones Coach Podcast, I share why energy highs and lows are so common in perimenopause and how cortisol, blood sugar, and hormone shifts work together to keep you on the roller coaster. We'll dive deep into the cravings–cortisol connection, why quick fixes like sugar or coffee make things worse, and the simple daily shifts that can help you create steady, all-day energy. You'll learn how to support your hormones, balance your blood sugar, and smooth out those frustrating energy crashes so you can feel focused, steady, and in control again. Hey Hormone Hotties:If you want to learn more about how you can work with me or what services I offer including those below- https://linktr.ee/TheHappyHormonesCoach Interested in being a guest expert (even if you are not in business but a woman who has a story to share) fill out the application and book an appointment. Affiliated Partner for awesome products in wellness and more including the "Body balancing" slenderize for a discount using my code HAPPY24 Join me in Happy Hormones Circle. This and my email list is where I will be focusing my time and content Disclaimer: The content shared in ‘The Happy Hormones Coach' podcast (including affiliate and non affiliate products) is for informational purposes only and is not intended as medical advice, diagnosis, or treatment. Please consult with a qualified healthcare provider before making any changes to your diet, exercise, or health routine. The opinions expressed in this podcast are those of the host and guests and do not necessarily reflect the views of any healthcare organizations. The statements made regarding any of the products that I mention have not been evaluated by the Food and Drug Administration (FDA). Individual results may vary.

In this solo podcast episode, Dr Mike Hart provides actionable, evidence-backed strategies to improve overall circadian rhythm and consequently enhance sleep quality. He discusses the importance of a regulated sleep-wake cycle and its impact on hormone release, metabolism, immune function, and general well-being. Various methods to maintain a healthy circadian rhythm are explored, including the benefits of morning sunlight exposure, the role of blue light blocking in the evening, and the timing of meals and exercise. He also touches on the effects of caffeine and alcohol on sleep, the ideal sleep environment, and additional supportive practices like social interaction, light physical activity, and evening routines that promote relaxation.   Links: Luminette 3 Glasses Light Therapy Box (10,000 lux standard) The Paleo Solution (Book)   Show Notes: (0:00) Welcome back to the Hart2Heart Podcast with Dr. Mike Hart (02:00) Morning sunlight: The key to a healthy circadian rhythm (07:00) Evening strategies for better sleep (09:00) Exercise and movement: Timing and types (14:30) Meal timing and its impact on sleep (19:00) The role of melatonin and caffeine (20:41) “Caffeine within six hours of bed can cost you a full hour of sleep.” (25:00) Alcohol and other sleep disruptors (30:00) Optimizing your sleep environment (33:00) Pre-sleep relaxation techniques — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

 You're eating healthy, moving your body, and following all the “rules” — so why is the scale still creeping up? In this episode of The Happy Hormones Coach Podcast, I break down the real reasons women in perimenopause gain weight despite doing everything “right.” We'll talk about how hormone shifts, lowered progesterone, fluctuating estrogen, and insulin resistance can change how your body stores fat. I'll share why old advice like “eat less, move more” can backfire, and what to do instead to work with your body, not against it. You'll walk away with a smarter, hormone-friendly plan that supports weight loss, energy, and overall health in this season of life. Hey Hormone Hotties:If you want to learn more about how you can work with me or what services I offer including those below- https://linktr.ee/TheHappyHormonesCoach Interested in being a guest expert (even if you are not in business but a woman who has a story to share) fill out the application and book an appointment. Affiliated Partner for awesome products in wellness and more including the "Body balancing" slenderize for a discount using my code HAPPY24 Join me in Happy Hormones Circle. This and my email list is where I will be focusing my time and content Disclaimer: The content shared in ‘The Happy Hormones Coach' podcast (including affiliate and non affiliate products) is for informational purposes only and is not intended as medical advice, diagnosis, or treatment. Please consult with a qualified healthcare provider before making any changes to your diet, exercise, or health routine. The opinions expressed in this podcast are those of the host and guests and do not necessarily reflect the views of any healthcare organizations. The statements made regarding any of the products that I mention have not been evaluated by the Food and Drug Administration (FDA). Individual results may vary.

 Think bloating is just about what you eat? Think again. In this episode of The Happy Hormones Coach Podcast, I share why bloating in perimenopause often has more to do with hormone shifts, stress, sluggish digestion, and water retention than it does with gluten or dairy. You'll learn the hidden triggers that keep you feeling puffy — even when your diet is “perfect” — and why over-restricting foods can actually make bloating worse. I'll walk you through practical, hormone-friendly strategies to support digestion, reduce water retention, and calm your nervous system so you can feel lighter and more comfortable without cutting out all your favorite foods. Hey Hormone Hotties:If you want to learn more about how you can work with me or what services I offer including those below- https://linktr.ee/TheHappyHormonesCoach Interested in being a guest expert (even if you are not in business but a woman who has a story to share) fill out the application and book an appointment. Affiliated Partner for awesome products in wellness and more including the "Body balancing" slenderize for a discount using my code HAPPY24 Join me in Happy Hormones Circle. This and my email list is where I will be focusing my time and content Disclaimer: The content shared in ‘The Happy Hormones Coach' podcast (including affiliate and non affiliate products) is for informational purposes only and is not intended as medical advice, diagnosis, or treatment. Please consult with a qualified healthcare provider before making any changes to your diet, exercise, or health routine. The opinions expressed in this podcast are those of the host and guests and do not necessarily reflect the views of any healthcare organizations. The statements made regarding any of the products that I mention have not been evaluated by the Food and Drug Administration (FDA). Individual results may vary.

Brain-computer interfaces, or BCIs, aim to enable people to control various adaptive devices directly with their thoughts. There are many BCI devices currently in various stages of development, with the potential to help people with ALS and similar conditions across many different activities of daily life. One particular area in which BCI devices may be able to support people with advanced ALS symptoms is communication. Many people with ALS rely on devices such as smartphones, tablets, and laptops to write or speak. All tools like these, collectively known as augmentative and alternative communication or AAC devices, need some kind of input to work. This could mean using a keyboard, a touchscreen, or, for people with advanced paralysis, an eye-gaze device. As ALS progresses, however, even eye gaze devices may become difficult for some people to use. BCIs—by allowing people to control AAC devices with their minds—could be a potential solution to this problem. Today, on Endpoints, we’re joined by two experts to discuss BCI technology and, in particular, its potential to help people with ALS continue to communicate. The views expressed in this podcast are those of the speakers and do not represent official endorsements by any organization. Kate Nilsen currently serves as an advisor to Synchron, a company developing a brain-computer interface (BCI) device. This device is investigational and is currently in clinical trials approved by the U.S. Food and Drug Administration (FDA). For those interested in staying informed about Synchron’s ongoing work and updates, please join the Synchron community: https://link.edgepilot.com/s/4239f747/ca21cbCpKkOSLI5ZXNqTdQ?u=https://www.synchronbci.com/StayConnected.htmlSupport the show: https://www.als.net/donate/See omnystudio.com/listener for privacy information.

In this edition of the Heart to Heart podcast, Dr. Mike Hart sits down with Todd Shapiro, CEO of Red Light Holland, a prominent figure in the psychedelic space. They discuss various aspects of psychedelic therapy, particularly focusing on psilocybin and its potential benefits for mental health, anxiety, and personal well-being. Todd shares his personal journey from working various jobs to becoming a key player in the psychedelic industry. They delve into recent developments in psychedelic research, the challenges of legalization, and the importance of proper protocols and responsible use. The conversation also highlights the role of microdosing and macro dosing, the differences between medicinal mushrooms and other psychedelics like MDMA and ayahuasca, and the future of psychedelic therapy.  Guest Bio and Links Todd Shapiro is the CEO of Red Light Holland, a publicly traded leader in legal psilocybin truffles and psychedelic research. A former top Canadian radio host turned mental health advocate, Todd champions safe, science-backed access to psychedelics, working with world-class researchers to advance policy reform and personal sovereignty. Follow him on X (Twitter) @ToddMShapiro Red Light Holland: http://redlight.co Third Wave: https://thethirdwave.co/microdosing-psilocybin-mushrooms-stamets-stack/?utm_source=chatgpt.com schedule35.co: https://schedule35.co/blog/paul-stamets-microdosing-protocol/?utm_source=chatgpt.com Show Notes: (00:00) Introduction to the Heart to Heart Podcast (01:30) Todd Shapiro's journey into psychedelics (03:30) Microdosing and its impact (13:30) Challenges and legalities of psychedelics (19:30) Advocacy and future of psychedelics (32:00) Concerns about unregulated psilocybin use (34:00) Regulated psilocybin sales in the Netherlands (37:00) Psilocybin administration methods (46:36) “The most clear anecdotal model of consistency… has got to be psilocybin. “ (49:30) Corporate influence on psychedelics (57:30) Global leadership in psychedelic research (59:30) Closing remarks and future prospects   --- The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart:   Instagram: https://www.instagram.com/drmikehart/  Twitter: https://twitter.com/drmikehart   Facebook: https://www.facebook.com/MikeHartEPS/   

Olestra (also known by its brand name Olean) is a fat substitute food additive that adds no metabolizable calories to products. It has been used in the preparation of otherwise high-fat foods, thereby lowering or eliminating their fat content. The Food and Drug Administration (FDA) approved olestra for use in the US as a replacement for fats and oils in prepackaged ready-to-eat snacks in 1996,[2] concluding that such use "meets the safety standard for food additives, reasonable certainty of no harm".[3]: 46399  In the early 2000s, olestra lost popularity due to supposed side effects and is largely phased out, but products containing the ingredient are available in some countries.

Send us a textFeeling stressed? You might be “managing” it in ways that actually make things worse.In this episode of The Happy Hormones Coach Podcast, I break down the most common stress relief habits that secretly sabotage your hormones — like nightly wine, constant sugar fixes, overtraining, and numbing out with screens. You'll learn how chronic stress impacts your cortisol, sleep, digestion, and weight in perimenopause, and why quick fixes keep you stuck in the cycle. I'll walk you through my simple 5-Minute Reset Method so you can calm your nervous system, lower stress, and start supporting your hormones — without adding more to your plate. Hey Hormone Hotties:If you want to learn more about how you can work with me or what services I offer including those below- https://linktr.ee/TheHappyHormonesCoach Interested in being a guest expert (even if you are not in business but a woman who has a story to share) fill out the application and book an appointment. Affiliated Partner for awesome products in wellness and more including the "Body balancing" slenderize for a discount using my code HAPPY24 Join me in Happy Hormones Circle. This and my email list is where I will be focusing my time and content Disclaimer: The content shared in ‘The Happy Hormones Coach' podcast (including affiliate and non affiliate products) is for informational purposes only and is not intended as medical advice, diagnosis, or treatment. Please consult with a qualified healthcare provider before making any changes to your diet, exercise, or health routine. The opinions expressed in this podcast are those of the host and guests and do not necessarily reflect the views of any healthcare organizations. The statements made regarding any of the products that I mention have not been evaluated by the Food and Drug Administration (FDA). Individual results may vary.

The Commissioner of the Food and Drug Administration (FDA), Dr. Marty Makary, shares what the FDA is doing to combat Americans' health concerns, including new approaches to medicine. He explains the changes made to SNAP, the Supplemental Nutrition Assistance Program, and how the federal government plans to regulate it beyond relying on grocery store management. Dr. Makary discusses President Trump's pursuit to lower drug prices for Americans and the impending pushback from pharmaceutical companies. Later, he shares an update about the Presidential Physical Fitness Test. Learn more about your ad choices. Visit podcastchoices.com/adchoices

In the past two months, several major U.S. food companies have voluntarily committed to removing artificial food dyes from their products, following a plan from the Food and Drug Administration (FDA) to work with the industry to phase out petroleum-based synthetic dyes. In June, Heinz and General Mills committed to removing synthetic dyes from all their products by the end of 2027, while Nestlé committed to their removal by the end of 2026. Tangle LIVE tickets are available!We're excited to announce that our third installment of Tangle Live will be held on October 24, 2025, at the Irvine Barclay Theatre in Irvine, California. If you're in the area (or want to make the trip), we'd love to have you join Isaac and the team for a night of spirited discussion, live Q&A, and opportunities to meet the team in person. You can read more about the event and purchase tickets here.Ad-free podcasts are here!To listen to this podcast ad-free, and to enjoy our subscriber only premium content, go to ReadTangle.com to sign up!You can read today's podcast⁠ ⁠⁠here⁠⁠⁠, our “Under the Radar” story ⁠here and today's “Have a nice day” story ⁠here⁠.Take the survey: What do you think about removing artificial dyes from food? Let us know!Disagree? That's okay. My opinion is just one of many. Write in and let us know why, and we'll consider publishing your feedback.You can subscribe to Tangle by clicking here or drop something in our tip jar by clicking here. Our Executive Editor and Founder is Isaac Saul. Our Executive Producer is Jon Lall.This podcast was written by: Isaac Saul and edited and engineered by Jon Lall. Music for the podcast was produced by Diet 75.Our newsletter is edited by Managing Editor Ari Weitzman, Senior Editor Will Kaback, Lindsey Knuth, Kendall White, Bailey Saul, and Audrey Moorehead. Hosted on Acast. See acast.com/privacy for more information.

In this exclusive interview, I spoke with Dr. Marty Makary, commissioner of the U.S. Food and Drug Administration (FDA), about his first 100 days in office and how he is transforming the agency.In this wide-ranging interview, we dive into his work to change food guidelines and drug approval processes, reduce supply chain vulnerabilities, and tackle conflicts of interest. We also address criticism of some of the FDA's recent decisions surrounding vaccines.Views expressed in this video are opinions of the host and the guest, and do not necessarily reflect the views of The Epoch Times.

Story at-a-glance Results of a two-year investigation found that the U.S. Food and Drug Administration (FDA) approved nearly 75% of new drugs between 2013 and 2022 without meeting its own basic standards Some cancer and Alzheimer's drugs were fast-tracked using surrogate markers like tumor shrinkage or protein levels, not real improvements in survival, memory, or function Dangerous side effects — including brain inflammation, hemorrhage, and blindness — were linked to drugs approved on minimal or flawed data, with thousands of deaths occurring each year The reporters created a searchable database on FDA drug approvals made between 2013 and 2022 — use it to check if any of your prescriptions meet the four scientific standards Always ask if a drug shows real-world benefits, look up its approval history, wait on new drugs, review your prescriptions, and work with a doctor who questions the system

On Saturday night, the U.S. military attacked several Iranian nuclear facilities in an attempt to eliminate their potential. Following the announcement, President Trump addressed the nation, boasting the U.S. "obliterated" Iran's nuclear capabilities. Some Americans fear this may drag the United States into an open-ended war. However, the Trump administration rejects those claims. Chairman of the House Intelligence Committee, Rep. Rick Crawford (AR-01) joins the Rundown to discuss what inspired the President to act in a swift, secretive manner while enabling the U.S. military to strike the Iranian nuclear facilities. He shares his hope that the strike will embolden the Iranian people to rise against their repressive regime.  President Donald Trump is taking a closer look at infant formula, a topic that the Food and Drug Administration (FDA) hasn't thoroughly examined in decades. The last comprehensive review of infant formula was conducted in 1998, over two decades ago. Currently, a new FDA panel is seeking answers regarding childhood diseases, such as obesity and diabetes. Former FDA Commissioner Dr. David Kessler, the author of "Diet, Drugs, and Dopamine: The New Science of Achieving a Healthy Weight," joins to discuss strategies for improving health, the popularity of Ozempic-like drugs, and whether or not food companies are trying to get us addicted to junk food. Plus, commentary from senior policy analyst at the Competitive Enterprise Institute, Ben Lieberman. Photo Credit: AP Learn more about your ad choices. Visit podcastchoices.com/adchoices

Story at-a-glance The U.S. Food and Drug Administration (FDA) allows U.S. food companies to use nearly 1,000 chemicals banned in Europe, many of which are linked to DNA damage, hormone disruption, or cancer Thanks to a legal loophole called “Generally Recognized as Safe” or GRAS, manufacturers are allowed to self-declare additives as safe without FDA approval, review, or even disclosure on the label Hidden additives are often disguised as “natural flavors” or “spices,” masking substances you'd never knowingly eat but are consuming regularly Ultraprocessed foods make up 73% of the U.S. food supply, designed with chemicals that increase cravings, damage gut health, and disrupt brain signaling Even after hospitalizations and deaths linked to hidden ingredients, the FDA rarely takes meaningful action — leaving your health in the hands of corporations