Podcasts about approvals

Ontario -Express Entry: Skilled Trades Stream – Suspension and Return of Applications, released by Ontario on  November 14 2025 Good day ladies and gentlemen, this is IRC news, I am Joy Stephen, a certified Canadian Immigration practitioner, and I bring to you this Provincial News Bulletin from the province of Ontario. This recording originates from the Polinsys studios in Cambridge, Ontario. Express Entry: Skilled Trades Stream – Suspension and Return of Applications  The Ontario Immigrant Nominee Program (OINP) has conducted a review of the OINP's Express Entry: Skilled Trades Stream (Skilled Trades Stream) and has identified systemic compliance and enforcement concerns relating to the stream.  In particular, the review identified systemic misrepresentation and/or fraud relating to Skilled Trades Stream eligibility criteria. These issues affect the ability of the director appointed under the Ontario Immigration Act, 2015 (Director) to determine whether applicants meet eligibility criteria.  As currently structured, the Skilled Trades Stream is vulnerable to systemic misrepresentation and/or fraud. This vulnerability undermines the Skilled Trades Stream's ability to meet the immediate labour market needs of the province, taking into account Ontario's limited nomination allocation. As a result, the Director:  has suspended receiving Skilled Trades Stream applications will return all outstanding Skilled Trades Stream applications in accordance with section 7 of Ontario Regulation 421/17 (Approvals under the Ontario Immigrant Nominee Program and Other Matters).  Applications that are returned will have their application fees refunded.  Applicants who remain interested in the program and meet the eligibility criteria for one of the other OINP's streams may submit a new Expression of Interest (EOI) to be considered for future draws.   |  You can always access past news from the Province of Ontario by visiting this link: https://myar.me/tag/on/. Furthermore, if you are interested in gaining comprehensive insights into the Provincial Express Entry Federal pool Canadian Permanent Residence Program or other Canadian Federal or Provincial Immigration programs, or if you require guidance after your selection, we cordially invite you to connect with us through https://myar.me/c. We highly recommend participating in our complimentary Zoom resource meetings, which take place every Thursday. We kindly request you to carefully review the available resources. Should any questions arise, our team of Canadian Authorized Representatives is readily available to address your concerns during the weekly AR's Q&A session held on Fridays. You can find the details for both of these meetings at https://myar.me/zoom. Our dedicated team is committed to providing you with professional assistance throughout the immigration proSupport the show

The Friday Five for November 14, 2025: iPhone Pocket Brings Back… Pockets. CMS Rural Health Transformation Program Government Shutdown Update Most-Favored Nation Drug Pricing CMS GENEROUS Model   Get Connected:

In today's Cloud Wars Minute, I unpack how Microsoft is empowering business users with new Copilot agents that simplify app creation and workflow automation — no coding needed.Highlights00:11 — Microsoft has launched a series of new agents for Microsoft 365 Copilot customers in the Frontier Program: App Builder and Workflows, designed to accelerate the creation of AI-driven apps and workflows. These agents make it incredibly easy for general business users to utilize natural language in order to create apps, workflows, and even additional agents.00:46 — The Workflows agent allows users to automate tasks such as email, mail apps, and calendar management across Outlook, Teams, SharePoint, Planner, and other services like Approvals. Steps of the automation are displayed in real time and follow the same Copilot conversation, making it easy to add more or edit existing workflow steps.01:24 — In a blog post, Charles Lamanna, President of Business and Industry Copilot at Microsoft, outlined a use case for these new agents: "Imagine you're preparing for a product launch with a few multi-turn interactions. Create an app for a product launch process where teams can track launch milestones, assign tasks, and view campaign progress in a dashboard."01:37 — "Send a Teams update every Monday with upcoming launch deadlines and key tasks from Planner. Post reminders for approval deadlines in Teams channels. Build an agent that answers product launch questions like: “What's the next milestone?”, “How do I submit creative assets?”, or “When is the launch event?”, using SharePoint resources and Teams conversations."02:08 — Regarding Microsoft's strategy for Copilot: step one involved integrating Copilot everywhere to ensure easy access and increasing familiarity. Step two was the launch of Copilot Studio Lite, which allows any user to build agents easily. Now, step three is focusing on finding the off-the-shelf agents available to make complex tasks such as app development and workflow automation seamless. Visit Cloud Wars for more.

Subscribe to UnitedHealthcare's Community & State newsletter.In this episode, Rob Lott interviews Jennifer Kao of the UCLA Anderson School of Management in front of a live audience about her paper in the October 2025 issue of Health Affairs exploring the impact of risk evaluation and mitigation strategies on generic approvals of US pharmaceutical products.Order the October 2025 issue of Health Affairs.Currently, more than 70 percent of our content is freely available - and we'd like to keep it that way. With your support, we can continue to keep our digital publication Forefront and podcast Subscribe to UnitedHealthcare's Community & State newsletter.

TransLink's Rapid Transit Program faces major funding hurdles as plans for nine new Bus Rapid Transit lines continue to stall.   Read the full article here: https://www.coastalfront.ca/read/translink-bus-rapid-transit-expansion-at-impasse-despite-approvals   PODCAST INFO:

Which bio/pharmaceuticals, launched or approved thus far in 2025, may be potential blockbusters (defined as drugs with sales of $1 billion or more) in the mid term, and what upcoming launches or approvals and trends should be on the industry's radar? Matthew Arnold, Principal Analyst and Content Strategist, Clarivate, provides the latest developments and insights.  Support the show

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In this episode of Dealer Talk with Jen Suzuki, I break down how to take everything from the previous service advisor lessons — warm greetings, Job-Risk-Reward (JRR), analogies, and MPI preparation — and execute a 2.0 follow-up call that drives approvals. I'll cover: How to personalize each call and start with a warm, human touch Using good news first to relax customers before addressing needed work Incorporating JRR and analogies to make repairs clear and relatable Strategies for texts and follow-ups when customers don't pick up Tracking approvals and keeping momentum for a seamless customer experience Dealer Talk with Jen Suzuki Podcast |

Good morning from Pharma and Biotech Daily: the podcast that gives you only what's important to hear in the Pharma and Biotech world. ##FDA Approves New Cancer TreatmentThe FDA has approved a new cancer treatment that has shown promising results in clinical trials. This treatment is expected to provide a new option for patients who have not responded well to traditional therapies. ##Drug Company Announces Major Breakthrough in Alzheimer's ResearchA drug company has announced a major breakthrough in Alzheimer's research, with a new drug that has shown significant improvement in cognitive function in patients with the disease. This breakthrough could potentially change the way Alzheimer's is treated in the future. ##Biotech Startup Raises $50 Million in FundingA biotech startup has raised $50 million in funding to further develop its innovative technology. This funding will allow the company to continue its research and development efforts, with the goal of bringing new treatments to market. ##Pharma Company Expands Manufacturing FacilitiesA pharmaceutical company has announced plans to expand its manufacturing facilities in order to meet growing demand for its products. This expansion will create new jobs and increase production capacity, allowing the company to better serve its customers. ##New Study Shows Promising Results for Diabetes TreatmentA new study has shown promising results for a potential new treatment for diabetes. The treatment, which targets a specific pathway in the body, has shown significant improvements in blood sugar levels and insulin sensitivity in patients with type 2 diabetes. ##Biotech Company Collaborates with Research Institute on Rare Disease TreatmentA biotech company has announced a collaboration with a research institute to develop a new treatment for a rare disease. This partnership brings together expertise from both organizations to work towards finding a cure for this debilitating condition. ##FDA Issues Warning About Counterfeit DrugsThe FDA has issued a warning about counterfeit drugs being sold online. These drugs may not contain the proper ingredients or may be contaminated, posing serious risks to consumers who purchase them. It's important to only buy medications from reputable sources to ensure safety and effectiveness.Support the show

In this week's Wilson Weekly on the Money Mentor Podcast, Rachael Howlett and Dr. Andrew Wilson break down the latest trends shaping Australia's property market. They explore why rental growth is steady despite historically low vacancy rates, unpack slowing building approvals for houses and units, and reveal why auction clearance rates remain strong across the country. From Sydney's dominance in unit approvals to Brisbane and Melbourne's mixed outcomes, this episode delivers data-driven insights with actionable takeaways for buyers, sellers, and investors.Discover our new tool: What's My Rental Home Yield? Money Mentor YouTube Channel: ‪@moneymentorauLink to Dr. Andrew Wilson on LinkedIn: / dr-andrewIf you enjoyed our podcast, make sure you follow and subscribe to stay up to date with the latest episodes.

Learning concepts is only half the battle — the real skill comes from practice. In this episode of Dealer Talk with Jen Suzuki, I share an interactive activity from my live classes that helps service advisors take everything they've learned — from warm greetings to Job-Risk-Reward explanations and analogies — and put it into action using real MPIs. I'll cover: How to use MPIs, photos, and videos to plan conversations Partnered role-play exercises to practice greetings, JRR, and analogies Tips for managers to coach their teams during practice Turning practice into confidence so live customer conversations feel effortless A weekly challenge: pick two MPIs, create analogies, practice, get feedback, and level up your team When advisors practice in a safe environment, their confidence rises, explanations become clear, and customer trust — and approvals — soar. Dealer Talk with Jen Suzuki Podcast |

PR isn't dead—it's evolved. And most brands are still playing by the old rulebook.In this episode we sit down with three communications leaders to dissect how modern PR actually works: Pippa Doyle (Global PR at Whoop), Shireen McDonagh (Brand & Content at Legacy Communications), and Niamh Hopkins (Head of Consumer PR at Legacy).This isn't theory. You'll hear the real story of how an agency changed a client's mind with a single email. Why Whoop runs exclusive events instead of chasing scale. How Krispy Kreme owned the news cycle in 24 hours when Leo Varadkar resigned. And why "freedom through structure" unlocks better creative than open-ended briefs.If you're a marketer, brand leader, or agency professional wondering why your PR feels stuck in 2010, this conversation will rewire how you think about communications, content, and building brand fame in a cluttered market.What You'll Learn:Why PR should be renamed "communications" (and what that shift actually means)The briefing framework that gets agencies to do their best workHow to turn one event into months of content across every channelThe truth about influencer numbers vs. engagement (and when each matters)Why budget constraints unlock creativity instead of killing itThe "brand newsroom" model and who should be your editor-in-chiefHow smaller brands can win with agility against bigger competitorsCHAPTERS:00:00 - Introduction: The Evolution of PR02:15 - Why "PR" Needs to Become "Communications"04:25 - Case Study: How One Email Changed a Client's Mind07:00 - What PR Actually Drives: Fame, Awareness & Word of Mouth10:04 - Why Great Campaigns Start With Great Briefs11:16 - The "Freedom Through Structure" Briefing Framework13:14 - Why Budget Can Be a Beautiful Constraint14:27 - Events as Content Machines, Not One-Day Moments18:27 - Measuring Event Success: Beyond Who Showed Up19:45 - Working With Influencers & Creators: Authenticity First23:06 - Does Follower Count Actually Matter?26:45 - Reactive Content Done Right: Aldi's Oasis & Krispy Kreme's Leo Moment28:00 - The Brand Newsroom Model: Operating Like a Publisher29:14 - Speed, Approvals & Team Alignment32:05 - Practical Advice: Setting Up Your Comms Function for Success37:52 - The Editor-in-Chief Role: Who Defends the Idea?with Legacy Communications Hosted on Acast. See acast.com/privacy for more information.

Specs, millimeters, torque, hydraulic pressure… customers check out FAST when advisors go “full tech mode.” That's where analogies change the game. In this episode of Dealer Talk with Jen Suzuki, I share one of my favorite techniques that helps customers understand repairs without feeling overwhelmed: turning technical jargon into relatable stories. I'll cover: Why customers decline work when they don't understand the language How to use simple, everyday analogies (like crayons, sneakers, or coffee filters) The power of humor and storytelling to reduce tension and win trust How to practice analogies as a team for fun, memorable customer experiences A weekly challenge: turn two MPI jobs into analogies and test them with your team When you swap tech talk for real talk, customers nod, laugh, and approve more often. Analogies make the complex simple — and that's where credibility (and sales) live. Dealer Talk with Jen Suzuki Podcast |

As CEO of City West Housing, Leonie King leads a committed team that develops affordable housing and provide housing services to some 1,600 residents in metropolitan Sydney.In this episode, Leonie King will be talking about affordable homes, funding, planning approvals, land costs, how can we get governmental outcomes for housing, private developers, and community housing providers working together to better to solve our housing crisis & much, much more.This podcast is brought to you in association with AWS, proud sponsors of our 2025 Residential series of podcasts.

October always hits different. The pressure to "lock in" for Q4, finish strong, and sprint to December is everywhere. But if you're already working weekends and drowning in Slack pings, that advice just adds weight. In this episode, I'm introducing a new segment: The CEO Briefing - your weekly download on what's happening in the founder space, what patterns I'm seeing on recovery calls, and the signals that should shape how you lead this week. This week's briefing covers: Why Q4 feels heavier than it should (and how to reframe it) The "locking in" trend and why it's broken for most founders The one-day contract that's eating your whole week Where all the energized, well-rested women have gone (and how to become one) Then I break down three filters that will save you 5-10 hours this week: Projects before pings Approvals at intervals Decision filters instead of daily reactions If you're tired of telling yourself "it'll calm down after Q4," this episode is your permission slip to stop waiting and start building the structure that gives you back your evenings, weekends, and energy. Links mentioned: Book a free 30-min Recovery Call: https://docs.google.com/document/d/1YsOE-H1gnkSnDvDTbpUmXLpixgLwDrGq17E2PFTsT6U/edit?usp=sharing  Learn about The CEO Studio (90-day private partnership): https://hollybray.com/studio  If this episode resonated, share it with another founder who needs it, or leave a review to help more people find the show.

October always hits different. The pressure to "lock in" for Q4, finish strong, and sprint to December is everywhere. But if you're already working weekends and drowning in Slack pings, that advice just adds weight. In this episode, I'm introducing a new segment: The CEO Briefing - your weekly download on what's happening in the founder space, what patterns I'm seeing on recovery calls, and the signals that should shape how you lead this week. This week's briefing covers: Why Q4 feels heavier than it should (and how to reframe it) The "locking in" trend and why it's broken for most founders The one-day contract that's eating your whole week Where all the energized, well-rested women have gone (and how to become one) Then I break down three filters that will save you 5-10 hours this week: Projects before pings Approvals at intervals Decision filters instead of daily reactions If you're tired of telling yourself "it'll calm down after Q4," this episode is your permission slip to stop waiting and start building the structure that gives you back your evenings, weekends, and energy. Links mentioned: Book a free 30-min Recovery Call: https://docs.google.com/document/d/1YsOE-H1gnkSnDvDTbpUmXLpixgLwDrGq17E2PFTsT6U/edit?usp=sharing  Learn about The CEO Studio (90-day private partnership): https://hollybray.com/studio  If this episode resonated, share it with another founder who needs it, or leave a review to help more people find the show.

Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma and Biotech world.President Trump has announced a 100% tariff deadline for pharmaceutical companies starting on October 1. However, companies that have already begun construction on manufacturing facilities in the U.S. are exempt from these tariffs. This move is part of the administration's efforts to lower drug prices and improve access to treatments for patients.In other news, Crinetics Pharmaceuticals has received FDA approval for their once-daily treatment for acromegaly, a rare pituitary condition. This approval marks a significant milestone for Crinetics and is expected to have a positive impact on patients' lives.Additionally, Lilly's oral SERD has been approved by the FDA for the treatment of breast cancer. This treatment has shown improved progression-free survival compared to standard therapy, offering new hope for patients battling this disease.The Trump administration is also preparing a proposed rule to further lower drug prices in the U.S., as part of an ongoing effort to align drug prices with other economically similar countries. These developments in the pharmaceutical industry are aimed at improving access to treatments and lowering costs for patients.

Bongani Bingwa speaks to David Fleminger, Chairperson of the Johannesburg Heritage Foundation about the difficulties residents and developers are facing in accessing building plans and allegations that officials have been soliciting bribes of up to R2,000, along with the disruptions caused by the closure of the Metro Centre. 702 Breakfast with Bongani Bingwa is broadcast on 702, a Johannesburg based talk radio station. Bongani makes sense of the news, interviews the key newsmakers of the day, and holds those in power to account on your behalf. The team bring you all you need to know to start your day Thank you for listening to a podcast from 702 Breakfast with Bongani Bingwa Listen live on Primedia+ weekdays from 06:00 and 09:00 (SA Time) to Breakfast with Bongani Bingwa broadcast on 702: https://buff.ly/gk3y0Kj For more from the show go to https://buff.ly/36edSLV or find all the catch-up podcasts here https://buff.ly/zEcM35T Subscribe to the 702 Daily and Weekly Newsletters https://buff.ly/v5mfetc Follow us on social media: 702 on Facebook: https://www.facebook.com/TalkRadio702 702 on TikTok: https://www.tiktok.com/@talkradio702 702 on Instagram: https://www.instagram.com/talkradio702/ 702 on X: https://x.com/Radio702 702 on YouTube: https://www.youtube.com/@radio702See omnystudio.com/listener for privacy information.

Can an AI‑native general ledger really automate the monthly close without losing control? Blake talks with Digits CEO Jeff Seibert about an “autonomous GL” built on a vector graph model, AI agents that research unknown transactions and auto‑reconcile to pixel‑matched statements, and human‑in‑the‑loop safeguards. Learn where Digits fits best today, how to pilot it with clients, price AI‑powered CAS, and keep trust with audit trails, object‑level permissions, and deterministic reporting.Chapters(01:20) - Understanding Autonomous General Ledgers (02:13) - Technical Architecture of Digits (05:29) - Real-World Application of Digits (10:10) - Advanced Features and Accuracy (16:09) - Automated Reconciliation (19:11) - Innovative Reporting Capabilities (24:19) - AI Agents in Accounting (28:40) - Automating Collections and Approvals (29:59) - Customizing Agent Instructions (30:46) - Balancing Simplicity and Complexity in Product Design (46:42) - Impact of AI on Accounting Roles (48:26) - Learning and Adapting to AI in Accounting (52:45) - Conclusion and Next Steps Sign up to get free CPE for listening to this podcasthttps://earmarkcpe.comhttps://earmark.app/Download the Earmark CPE App Apple: https://apps.apple.com/us/app/earmark-cpe/id1562599728Android: https://play.google.com/store/apps/details?id=com.earmarkcpe.appConnect with Our Guest, Jeff SeibertWebsite: https://jeffseibert.com/LinkedIn: https://www.linkedin.com/in/jseibert/Learn more about DigitsWebsite: https://digits.com/Connect with Blake Oliver, CPALinkedIn: https://www.linkedin.com/in/blaketoliverTwitter: https://twitter.com/blaketoliver/

Thank you so much for listening to the Bob Harden Show, celebrating over 14 years broadcasting on the internet. On Tuesday's show, we visit with Florida State Senator Kathleen Passidomo about the assassination of Charlie Kirk and his celebration of life. We visit with Energy Policy Expert for Americans for Prosperity Faith Burns about the vulnerability of our energy grid and the need to speed up regulatory approvals. Boo Mortenson and I discuss some of the benefits but also the threats of Artificial Intelligence to human intelligence and development. We also visit Linda Harden about President Trump's announcement yesterday about developing science on autism and vaccine schedules. Please join us tomorrow when we visit with Cato Institute Chairman Emeritus Bob Levy and Professor Andrew Joppa. Access this or past shows at your convenience on my web site, social media platforms or podcast platforms.

Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma and Biotech world. Pfizer has made a comeback in the obesity market with the acquisition of Metsera for $4.9 billion, rejuvenating its portfolio after facing challenges with three discontinued assets. Meanwhile, Stealth BioTherapeutics has received expedited FDA approval for the first-ever treatment for Barth syndrome, and Sanofi's decision on their oral multiple sclerosis drug has been postponed to December. The ACIP committee has expressed concerns about a lack of knowledge and experience within the reconstituted committee. Biotility offers industry-recognized credentials to advance bioscience careers, Novartis is exploring ways to reduce drug costs in the US, and Merck has received approval for a subcutaneous formulation of Keytruda. Stay tuned for more updates on the psychedelics space, rare disease treatments, and other developments in the biopharmaceutical industry.

Thank you so much for listening to the Bob Harden Show, celebrating over 14 years broadcasting on the internet. On Tuesday's show, we visit with Florida State Senator Kathleen Passidomo about the assassination of Charlie Kirk and his celebration of life. We visit with Energy Policy Expert for Americans for Prosperity Faith Burns about the … The post The Vulnerability of Our Energy Grid and the Need to Speed Up Regulatory Approvals appeared first on Bob Harden Show.

Joyce discusses the approval of 48 of President Trump's picks in a single vote following rule changes. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today is Friday, Sept. 19, 2025. The Brainerd Dispatch Minute is a product of Forum Communications Co. and is brought to you by reporters at the Brainerd Dispatch. Find more news throughout the day at BrainerdDispatch.com.

We are talking Ghostbusters on the April 2024 Party in the Back Podcast. President of Business Operations from the Fort Wayne Komets Scott Sproat and Jon Long Manager the Event Presentation & Creative Content for the Edmonton Oil Kings join the podcast to talk about their success with this Movie theme night.Scott and Jon drop insights on all aspects of their promotion, including:Approvals and support from movie studio and rights holdersLeading their team's creative effortPopular fan elements for their Ghostbusters NightSocial Media elementsScoreboard additionsJersey Auctions, like the Komets $13,000 charity jersey auctionMusic and bumpers, including a one night change in the Oil Kings Goal songSponsor integrations and more...

First impressions are money in the service drive. In this episode of Dealer Talk with Jen Suzuki, we dig into the relational greeting — the difference between being just another transactional advisor and being the trusted pro customers return to again and again. I'll walk you through how to: Show up with the right energy (because customers feel it before you speak) Use names, humor, and personal touches to build instant trust Transition naturally from small talk to business without feeling “robo” Make customers feel like people, not VIN numbers Turn a check-in into the start of a relationship that drives approvals and loyalty This isn't theory — it's what I see working every week in dealerships. If your service team can nail this, the rest of the process gets easier, approvals go up, and income potential climbs. Dealer Talk with Jen Suzuki Podcast |

How do you get your executive pastor to give a "yes" to all your requests?We're joined by our Southeast Church friends today to continue our Executive Pastor and Tech podcast series. In this episode you'll hear: 1:00 Blake's hilarious church tech mic moment4:55 Southeast Christian Church team joins the podcast6:50 Five Truths and a Lie: church production edition16:00 What an executive pastor really does in church leadership18:30 How church techs can build trust with their executive pastor23:15 How to get a “yes” from your executive pastor as a church tech33:15 The right way to ask your executive pastor for resources or budget41:30 When church gear fails (and you warned it would)45:45 System failure stories in church production52:00 Why the church tech–integrator relationship matters1:01:00 Handling tension with your executive pastor as a church production leader1:07:10 Why church techs should talk about non-work things with pastorsCheckout HouseRight's solutions for your church and open jobs here. Resources for your Church Tech Ministry Sell Us Gear: Does your church have used gear that you need to convert into new ministry dollars? We can make you an offer here. Buy Our Gear: Do you need some production gear but lack the budget to buy new gear? You can shop our gear store here. Connect with us: Sales Bulletin: Get better deals than the public and get them earlier too here! Early Service: Get our best gear before it goes live on our site here. Instagram: Hangout with us on the gram here! Reviews: Leaving us a review on the podcast player you're listening to us on really helps the show. If you enjoyed this episode, you can say thank you with a review!

This one's for the service team (but sales, you should listen too—because everybody's in sales). In this kickoff to my new Service Team Series on Dealer Talk with Jen Suzuki, I break down the Service Cheat Code: how preparation before the customer even shows up changes everything. From reviewing history and declined work to checking recalls, parts, and notes, I share the exact steps that turn rushed, transactional check-ins into confident, relational experiences that win trust and drive approvals. These are the same hacks I train advisors on in dealerships every single week—practical, now, and proven to increase income potential. This episode is your game plan for better connections, smoother days, and higher CSI scores. Dealer Talk with Jen Suzuki Podcast |

Two Onc Docs, hosted by Samantha A. Armstrong, MD, and Karine Tawagi, MD, is a podcast dedicated to providing current and future oncologists and hematologists with the knowledge they need to ace their boards and deliver quality patient care. Dr Armstrong is a hematologist/oncologist and assistant professor of clinical medicine at Indiana University Health in Indianapolis. Dr Tawagi is a hematologist/oncologist and assistant professor of clinical medicine at the University of Illinois in Chicago. In this episode, OncLive On Air® partnered with Two Onc Docs to feature a conversation about soft tissue sarcoma management. Drs Armstrong and Tawagi discussed that soft tissue sarcomas represent a rare and heterogeneous group of malignancies that arise from mesenchymal cells rather than epithelial cells and encompass several distinct histologic subtypes. They explained that although uncommon, these sarcomas are frequently emphasized in board examinations, partly because their management has historically been stable, though recent FDA approvals and ongoing research have expanded therapeutic options. They noted that risk factors may include prior radiation exposure, environmental agents, and viral infections. Additionally, they shared that chronic lymphedema is associated with angiosarcoma, whereas rare hereditary syndromes may predispose individuals to specific sarcoma subtypes.  Clinically, they explained that sarcomas may arise anywhere in the body, though many occur in the thigh, buttocks, or groin, typically presenting as painless, enlarging masses often mistaken for benign lesions. They emphasized that diagnosis requires core needle biopsy to preserve tissue architecture and that staging relies on MRI of the primary site and CT of the chest, given the strong predilection for pulmonary metastases. They also summarized the five subtypes of soft tissue sarcoma—synovial, clear cell, angiosarcoma, rhabdomyosarcoma, and epithelioid. They reported that the cornerstone of localized disease management is surgical resection, preferably limb-sparing when feasible, combined with radiation for larger or high-risk tumors. They also highlighted novel strategies like immunotherapy. For metastatic disease, they stated that surgical resection of pulmonary metastases can achieve durable remissions in select patients. 

Buy here, pay here dealership Oak Motors is slowing approval of credit applications as long-term affordability concerns persists and despite increased volume.  Anderson, Ind.-based Oak Motors' applications were up 30% year over year at the beginning of September, according to data the dealership group provided to Auto Finance News. The dealership group did not specify the number of applications. The increase comes despite a drop in sales and amid a decline in approvals at the dealership group, which has five locations in Indiana, Executive Board Member Tiger Okeley told AFN. “We've seen about a 20% decrease in sales, and that's by design,” he said, without providing specific sales numbers. Oak Motors focuses on identifying consumers who can commit to long-term deal structures that are beneficial to the consumers and the dealership, he said.  While the BHPH dealership sells as many vehicles as it wants to sell, success depends on finding customers capable of keeping up with weekly payments, Okeley said.  “If they stop paying us, it didn't matter if we sold them a car,” he said. The bottom line is “we didn't get paid.”  BHPH is attractive to customers with risky credit profiles or those who don't have access to traditional financing, Okeley said. Some BHPH dealerships offer customers a chance to rebuild their credit to qualify for traditional financing down the road. In fact, an inaugural survey of 1,015 consumers across the country published by Oak Motors on Aug. 15 revealed that 32% of consumers avoided applying for an auto loan due to concerns about their credit score this year.  Hear more about Oak Motor's credit survey results, market trends and the state of the buy here, pay here market in this week's podcast. This episode is sponsored by The Work Number by Equifax. Auto Finance Summit, the premier industry event for auto lending and leasing, returns Oct. 15-17 at the Bellagio Las Vegas. Learn more about the 2025 event and register here. 

Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma and Biotech world. Robert F. Kennedy Jr. faced the Senate Finance Committee in a tense hearing amidst calls for the removal of the health secretary. The committee questioned Kennedy on his recent actions, including the firing of CDC director Susan Monarez. Meanwhile, the FDA's new rare disease pathway received mixed reactions, with some questioning its tangible impacts. AC Immune downsized and refocused its pipeline, while Kennedy proposed adding seven new vaccine advisors to the ACIP. Other news included successful RNA editing in an AATD study, demands for YouTube to remove anti-vaccine videos, and a new framework for rare disease approvals by the FDA. Thank you for tuning in to today's episode of Pharma and Biotech daily.

We returned from the Labor Day holiday to a spate of intriguing deals, including two that could surpass $2 billion: Vertex's new pact with Enlaza for autoimmune disease—which the Casgevy maker hopes could ease conditioning for the sickle cell/beta thalassemia gene therapy—and Novartis' agreement with Arrowhead for neurodegenerative diseases such as Parkinson's.  But as we look ahead, Thursday's Senate Finance Committee will be the focus this week, as Health and Human Services Secretary Robert F. Kennedy Jr. will answer questions after the ousting of CDC Director Susan Monarez. Her departure is reportedly linked to changes to the regulation of COVID-19 vaccines, for which the FDA last week issued restricted approvals to Moderna, Pfizer/BioNTech and Novavax and rescinded the emergency use authorizations. The next ACIP meeting—where COVID-19 vaccines will be on the agenda—is set for Sept. 18 and 19.   In the weight loss arena, Novo Nordisk presented results from a real-world study this weekend at the European Society of Cardiology Congress in Madrid showing that Wegovy cut the risk of heart attack, stroke or death by 57% compared to Eli Lilly's tirzepatide in people with obesity and cardiovascular disease. The company also continues to throw money into the space, last week inking a $550 million deal with Replicate for RNA-based treatments for obesity and diabetes. Meanwhile, Lilly is dropping studies of one oral obesity candidate as another nears a regulatory filing. Finally, the FDA greenlit the first GLP-1 generic for obesity.   We also discuss reactions to the FDA's new guidance on radiopharma drug development, four recent approvals for rare diseases, and everything you ever wanted to know about SPACs. 

Following its 2024 overhaul, MM2H posted an 84% boost in inflows, including RM237 million in property and RM597 million in deposits.View the full article here.Subscribe to the IMI Daily newsletter here. 

US President Donald Trump signed the “Enabling Competition In The Commercial Space Industry” Executive Order (EO). Gilat Satellite Networks has been awarded a multimillion dollar contract by Israel's Ministry of Defense for the delivery and integration of satellite communication systems (SATCOM) and services. The Italian Space Agency (ASI) has signed an agreement with SpaceX for an uncrewed mission to Mars aboard a future Starship mission, and more. Remember to leave us a 5-star rating and review in your favorite podcast app. Be sure to follow T-Minus on LinkedIn and Instagram. T-Minus Guest Our guest today is Luis Torres, founder of Torres Orbital Mining (TOM).  You can connect with Luis on LinkedIn, and find out more about TOM on their website. Selected Reading Enabling Competition in the Commercial Space Industry – The White House Gilat receives a multimillion contract from Israel's Ministry of Defense for advanced strategic defense SATCOM project Agenzia Spaziale ITA (@ASI_spazio) / X Spire Global Announces Preliminary Second Quarter 2025 Revenue and Provides Business Update KBR and Axiom Space Successfully Complete Initial Crewed Spacesuit Tests in NASA's Neutral Buoyancy Lab Space Kinetic Corp. LinkedIn This real 'Eye of Sauron' spits out ghost particles in space. Here's what it looks like T-Minus Crew Survey Complete our annual audience survey before August 31. Want to hear your company in the show? You too can reach the most influential leaders and operators in the industry. Here's our media kit. Contact us at space@n2k.com to request more info. Want to join us for an interview? Please send your pitch to space-editor@n2k.com and include your name, affiliation, and topic proposal. T-Minus is a production of N2K Networks, your source for strategic workforce intelligence. © N2K Networks, Inc. Learn more about your ad choices. Visit megaphone.fm/adchoices

‘Abundance v Sufficiency: Dawn of Justice' T-Shirt Edition With a sufficiency of sufficiency-themed t-shirts now on the streets, the universe is out of balance and your intrepid hosts need to balance the sufficiency yin with an abundance yang! And OH BOY did we have an abundance of abundance-themed t-shirt ideas for you. YOU need not have Abundance FOMO any longer. Run, don't walk to our merch page and grab the limited edition Abundance tee: www.letmesumup.net/p/merch/.—It's Productivity Palooza 2025 and invited to the hottest party in town (this here podcast of course) is the one and only Alison Reeve who joins your intrepid hosts in a Productivity Commission report launch party! Landing in Jim Chalmers' hot little hands before the big Economic Reform Roundtable in Canberra (the other hottest party in town), the PC's interim report, “Investing in Cheaper, Cleaner Energy and the Net Zero Transformation” has a grab bag of ideas: Adaptation - getting its moment, finally! Approvals - strike teams and make em' fast! Carbon pricing - safeguard harder! Also check out this excellent OpEd from Alison in the AFR.Our main courseI'm Wonky But I'm Worth It might have been the unofficial subtitle of the latest contribution to reform of the National Electricity Market by expert panel Tim Nelson, Paula Conboy, Ava Hancock and Phil Hirschhorn. That's right, your intrepid hosts evidently didn't have anything else to do last weekend than consume the 220-page elephant of the “National Electricity Market wholesale market settings review” draft report (we did, but we read it anyway – you're welcome). While heavy on financial jargon, we wonder whether this might be the political bullet proof vest this policy needs, lest the ESEM join the acronym soup grave of NEM review solutions past! Targeted upgrades to existing architecture across the spot market (visibility of DER!), medium-term derivatives (more liquidity via market-making obligations!) and long-term investment signals (enter, Electricity Services Entry Mechanism!) with a partridge in a pear tree and consumer reforms (the epilogue that Frankie thinks deserves a prologue). One more thingsTennant's One More Thing is: the greatest movie ever made!? WARNING: 3.5 hours and carbon monoxide poisoning awaits.Frankie's One More Thing is: a watching brief on the expert panel on atmospheric measurement of fugitive methane emissions in Australia, chaired by former chief scientist Dr Cathy Foley, and just how this might contribute to policy - Global Methane Pledge, ahem!Alison's One More Thing is: is the gas network problem solving itself? A Victorian gas utility helping customers go all-electric feels like cause for celebration in putting consumers first!Luke's One More Thing is: a shout out and salute to outgoing Clean Energy Council CEO Kane Thornton, for his tireless work supporting and leading the growth of Australia's renewables industry and for being an all-round awesome human. Go well and see you soon Kane!And that's it for now, Summerupperers. There is now a one-stop-shop for all your LMSU needs: head toletmesumup.netto support us on Patreon, procure merch, find back episodes, and leave us a voicemail!

Housing is on the agenda at next week's productivity roundtable, with the Treasurer wanting better regulation and faster approvals to build more homes.Mentioned in this episode:Sign up to The Conversation's newsletterhttps://theconversation.com/au/newsletters

Shoot us a Text.Episode #1118: Auto loan approvals are climbing as vehicle demand heats up, Jaguar doubles down on its high-dollar EV future, and a new survey shows U.S. shoppers are still splurging on impulse buys.Show Notes with links:New data shows consumers may finally be catching a break in the auto loan market. Approvals are up, interest in buying is growing, and middle-income shoppers are more willing to make sacrifices to keep their vehicles.The New York Fed says auto loan rejection rates dropped sharply in Q2 2025 to 6.7%, down from a painful 19% last year.14% sought a loan in the past year, and more expect to apply in the coming months.Santander's latest survey shows 55% of middle-income consumers plan to buy a vehicle in the next 12 months, the highest reading in two years.Tariff fears are real: 18% of respondents sped up a big purchase in Q2 because of price uncertainty, with 41% of those buying a vehicle.Santander says this is the first time in eight quarters that buyers outnumber those delaying a purchase — a sign pent-up demand could finally be turning into sales.Jaguar is set on an electric, ultra-luxury future. Despite some loud critics, the brand is preparing a bespoke EV platform and three six-figure models designed to take on the industry's elite.Incoming JLR CEO PB Balaji says the brand's EV strategy is locked in, with positive early feedback from customers.Production of all current Jaguars except the F-Pace ended last year as the company stockpiled inventory.First new model — the GT — is a sleek, 600-hp electric sedan with about 425 miles of range and a $150K price tag, expected late next year as a 2027 model.A large, three-row electric crossover will follow in late 2027 or early 2028.The third entry is rumored to be a large, ultra-luxury electric sedan aimed at Rolls-Royce and Bentley buyers, due around 2030.While many Americans say they're trying to rein in discretionary spending, a new survey shows the vast majority still made at least one unplanned purchase last month.Optimum Retailing survey finds 72% of Americans made an unplanned in-store discretionary purchase in the past month.While 34% plan to cut back in the next six months, sales events (55%), eye-catching displays (45%), and immediate availability (26%) make spending hard to resist.Only 5% said in-store shopping no longer feels “worth it.”Many shoppers are sticking to a budget by cutting dining/takeout (48%), clothing/accessories (44%), and electronics/gadgets (37%).“Consumers today are cautious, but not unengaged… The moment and experience must both feel correct,” said Sam Vise, CEO of Optimum Retailing.Join Paul J Daly and Kyle Mountsier every morning for the Automotive State of the Union podcast as they connect the dots across car dealerships, retail trends, emerging tech like AI, and cultural shifts—bringing clarity, speed, and people-first insight to automotive leaders navigating a rapidly changing industry.Get the Daily Push Back email at https://www.asotu.com/ JOIN the conversation on LinkedIn at: https://www.linkedin.com/company/asotu/

The newest wedge driving Canada and the U.S. apart? Skimmed milk powder, apparently. Like a straight-A high schooler whose grades drop at university, Health Canada is struggling with an increased workload.

Greg Brady spoke with Dr. Mike Moffatt, Economist, Founding Director, PLACE Centre. Co-Host, "Missing Middle" about, are the City of Toronto claimed improvements in housing application timelines real or an illusion? Learn more about your ad choices. Visit megaphone.fm/adchoices

The initial results are in for the pilot effort to improve the cloud security program known as FedRAMP, four vendors have crossed the finish line to receive low authorizations under FedRAMP, proving the faster process is working for more on how the General Services Administration plans to continue to improve FedRAMP, federal news networks executive editor Jason Miller joins me nowSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Anton from Drop Ship Lifestyle addresses a common question regarding the difficulty of obtaining brand authorization using his dropshipping techniques. He details the process and shares tips for securing brand approval, highlighting the importance of building a strong brand presence for business growth. Learn about brand approval and how to make money online!

The Uptime hosts examine Interior Secretary Doug Burgum's federal oversight mandate, the administration's plan to replace Idaho's cancelled Lava Ridge Wind Farm with six nuclear reactors, and critique a recent wind conference in Australia. The discussion also covers French utility EDF's plan to sell 50% of its North American wind portfolio to raise 2 billion euros for nuclear upgrades in France. Sign up for the next SkySpecs webinar! Register for  UK Offshore Wind Supply Chain Spotlight 2025! Sign up now for Uptime Tech News, our weekly email update on all things wind technology. This episode is sponsored by Weather Guard Lightning Tech. Learn more about Weather Guard's StrikeTape Wind Turbine LPS retrofit. Follow the show on Facebook, YouTube, Twitter, Linkedin and visit Weather Guard on the web. And subscribe to Rosemary Barnes' YouTube channel here. Have a question we can answer on the show? Email us! Allen Hall: [00:00:00] Mark your calendars December 11th at the Royal Highland Center in Edinburgh, because you'll want to be at the UK offshore wind supply chain Spotlight 2025. This isn't just another conference. It's where the UK's offshore wind supply chain comes together. Co-hosted by ORE Catapult and the Offshore Wind Growth Partnership. Spotlight 2025 is where developers connect with suppliers and where the next breakthrough in offshore wind technology gets its moment to shine. So whether you're looking to forge new partnerships, secure critical investments, or simply stay ahead of the curve in this rapidly evolving sector, you'll need to register for this event. Remember December 11th in Edinburg for Spotlight 2025. Just Google. Edinburgh Supply Chain Spotlight 2025. You can register today. You're listening to the Uptime Wind Energy Podcast, brought to you by bill turbines.com. Learn train and be a part of the Clean Energy Revolution. [00:01:00] Visit build turbines.com today. Now here's your hosts, Alan Hall, Joel Saxon, Phil Tartaro, and Rosemary Barnes.  Allen Hall: Well, greetings from Charlotte, North Carolina to the Queen City. I'm Alan Hall and I'm here with Phil Tartaro from the Golden State of California. And Joel Saxon is at an undisclosed location in a secure bunker, so that's not gonna leak out where he is. And Rosemary is enjoying the winter months in beautiful Australia. And we have some interesting topics this week, but I wanna lead off with Rosemary. Went to another WIN conference, WIN plus conference in Australia. Rosemary.  Rosemary Barnes: Yeah, actually I, I feel petty, um, dissing this conference now because this is the one that Alan, you and I did a whole episode on how bad this conference was last year and, um. That's what caused us to feel like we needed to organize our own wind energy conference. Uh, that covered some technical topics, but you're walking around the conference, like, why is there so much hydrogen stuff at a wind energy conference? And I'm like, okay, well maybe that's like what they perceive that, you know, most of the [00:02:00] new projects in Australia, all the big ones say that they're associated with hydrogen. So maybe that's it. And then I started seeing a lot of, um, carbon capture things and, you know, like eels and all sorts of, all sorts of things related to. CO2. Um, so that confused me. Um, and then I saw that it was also a carbon capture conference too. So yeah, the exhibition was, was not, not too bad. I had definitely had lots of good conversations with people. Um, some interesting things like, um, the drone, uh, yeah, drone inspections, a few new capabilities coming up. There were a couple of people with good drones, um, that can. Test the resistance of an LPS and say that they can do a whole turbine in an hour and a half. So, um, that's, that's pretty good. There was also some cool NDT, uh, non-destructive testing stuff and a really small portable ultrasound machine, and they wouldn't give me a price,

Editor's Summary by Linda Brubaker, MD, and Preeti Malani, MD, MSJ, Deputy Editors of JAMA, the Journal of the American Medical Association, for articles published from July 12-18, 2025.

Welcome to this special episode of the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice. For major FDA decisions in the field of neurology, we release short special episodes to offer a snapshot of the news, including the main takeaways for the clinical community, as well as highlights of the efficacy and safety profile of the agent in question. In this special FDA-focused episode of Mind Moments, migraine expert Stewart Tepper, MD, professor of neurology at the Geisel School of Medicine at Dartmouth, discusses the recent FDA approvals of STS101 (Atzumi; Satsuma Pharmaceuticals) and CT-132 ( ) for the acute and preventive treatment of migraine. Tepper breaks down the pharmacological profile and clinical utility of DHE, the formulation behind STS101, and how the latest delivery innovations may expand its use in acute migraine care. He also dives into the approval data behind CT-132, the first-ever FDA-approved prescription digital therapeutic for migraine, and what it could mean for patients and clinicians alike. Tepper highlights the need for clinician education as novel therapeutics reshape the treatment landscape and offers insight into how these new tools could improve patient outcomes with fewer side effects and better accessibility. For more of NeurologyLive's coverage of STS101 and CT-132 for migraine, head here: FDA Approves STS101 Nasal Powder as New Treatment for Acute Migraine FDA Approves CT-132 as First Digital Therapeutic for Preventive Treatment of Episodic Migraine Episode Breakdown: 1:10 – Overview of DHE, patient suitability, and STS101's place in treatment 6:05 – Efficacy and safety data from the ASCEND and SUMMIT trials for STS101 10:20 – The expanding migraine toolbox and need for clinician education 15:10 – CT-132's first-in-class status and clinical trial data 16:25 – Clinical use of CT-132 as an add-on preventive 19:30 – The knowledge gap on digital therapeutics and educating the neurology community 23:00 – Future directions and hopes for expanded CT-132 research Thanks for listening to the NeurologyLive Mind Moments podcast. To support the show, be sure to rate, review, and subscribe wherever you listen to podcasts. For more neurology news and expert-driven content, visit neurologylive.com.

Good morning from Pharma and Biotech Daily: the podcast that gives you only what's important to hear in Pharma and Biotech world.The FDA has rejected Capricor's therapy for Duchenne Muscular Dystrophy (DMD), causing shares to plunge due to insufficient evidence of effectiveness for cardiomyopathy associated with DMD. Lilly and Sarepta also received Complete Response Letters (CRLs) for their therapies. Moderna has won full approval for its COVID-19 vaccine for higher-risk kids, while Pacira has cut staff in San Diego. The FDA has released a cache of CRLs, providing insights into the journeys to market for various drugs. AbbVie has acquired Ichnos Glenmark's lead myeloma antibody, and Ultragenyx's stock plummeted after a late-stage trial disappointment. Kennedy postponed a preventive care panel meeting after a Supreme Court win. Transitioning from one piece of news to the next, let's move on to the webinar exploring digitization strategies for drug development. Stay tuned for more updates in the pharmaceutical industry.

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On episode 844 of WHAT THE TRUCK?!? Dooner is catching up with SearchCarrier's Garrett Allen. His new site allows you to easily look up any carrier and see how often it's been put out of service, inspected and more. We're also diving into his blitz week dashboard to break down this year's top violations. Konexial's Jerry D'Addesi on the latest in AI load matching, double broker prevention and edge computing. Is the FMCSA starting to take freight fraud more seriously? After FMCSA's identity verification became mandatory in April 2025, published authority counts dropped by over 50%. We'll take a look at the numbers.  And in headlines: tariffs on, tariffs off; fast food restaurants vs fleet sizes; excessive LEGO sets and more.  Chapters 3:04 New authority approvals down 50% 5:19 Tariffs on, tariffs off, tariffs on 8:16 Fleet sizes vs. fast food restaurant locations 10:52 Konexial | Jerry D'Addesi 16:54 FreightTech innovations | Jerry D'Addesi 20:15 Too much LEGO 22:40 SearchCarriers | Garrett Allen 27:41 Blitz week breakdown | Garrett Allen Catch new shows live at noon EDT Mondays, Wednesdays and Fridays on FreightWaves LinkedIn, Facebook, X or YouTube, or on demand by looking up WHAT THE TRUCK?!? on your favorite podcast player and at 5 p.m. Eastern on SiriusXM's Road Dog Trucking Channel 146. Watch on YouTube Check out the WTT merch store Visit our sponsor Subscribe to the WTT newsletter Apple Podcasts Spotify More FreightWaves Podcasts Learn more about your ad choices. Visit megaphone.fm/adchoices