Podcasts about 3B

Van Lai-DuMone, founder of worksmart Advantage, is a dynamic force redefining how teams harness creativity and curiosity in the workplace through her groundbreaking Creative Integration™ method. With 20+ years of experience spanning startups to industry giants like Google and LinkedIn, she designs transformative learning experiences that drive innovation from the inside out. A TEDx speaker and author of What If Pigs Can Fly?, Van draws deep inspiration from her mother—a Vietnamese refugee who became one of the first licensed Vietnamese manicurists in the U.S., igniting an $8.3 billion industry. Van's work is a bold invitation to reimagine what's possible when curiosity leads the way. 

Reading by David Anderson ---   2 Kings 18; 2 Chronicles 29-31; Psalm 48   https://www.biblegateway.com/passage/?search=2%20Kings%2018%3B%202%20Chronicles%2029-31%3B%20Psalm%2048&version=ESV&interface=print

Owen Caissie: Pete Crow-Armstrong is 'the most gifted ballplayer I've ever played with' (Hour 2) full In the second hour, David Haugh and Bruce Levine talk with Cubs #1 prospect Owen Caissie on the noise he's heard surrounding the trade deadline and his path to the majors, they discuss if Luis Robert Jr. will stay with the White Sox past the trade deadline, and debate if the Cubs patience is running thin with Matt Shaw at 3B. 2727 Sat, 19 Jul 2025 17:20:00 +0000 StolaxgBDnZNEwdn0yx3d7ZvGLFMIDDi sports Inside The Clubhouse sports Owen Caissie: Pete Crow-Armstrong is 'the most gifted ballplayer I've ever played with' (Hour 2) Bruce Levine and David Haugh host Inside the Clubhouse, discussing the latest Cubs, White Sox and MLB storylines while also welcoming on great guests from across the baseball landscape. 2024 © 2021 Audacy, Inc. Sports False

SUMMARYIn this episode of "Right About Now with Ryan Alford," Ryan breaks down seven major business stories shaping the week. Topics include MLB's new automated umpire system, Microsoft's surge in AI-driven ad revenue, Stripe's $3B employee tender offer and IPO delay, Amazon's FTC lawsuit over Prime's “dark patterns,” TikTok Shop's rapid trend shifts, Starbucks' real-time pricing experiment, and Delta Airlines' fintech-like diversification. Ryan highlights how speed, innovation, and data-driven decisions are disrupting legacy business models, urging listeners to adapt quickly or risk falling behind.TAKEAWAYSIntroduction of automated ball and strike challenge system in MLB, emphasizing data-driven decision-making.Microsoft's significant Q3 earnings, highlighting $20 billion in advertising revenue and advancements in AI-driven ads.Stripe's $3 billion employee tender offer and the strategic delay of its IPO, focusing on private market advantages.Legal challenges faced by Amazon regarding deceptive practices in Prime enrollment and cancellation processes.TikTok Shop's July trend report showcasing rapid shifts in consumer demand and the need for agile supply chain management.Starbucks experimenting with real-time pricing transparency to enhance customer experience and adapt to market demands.Delta Airlines' strong Q2 performance and diversification strategies, resembling fintech operations rather than traditional airline metrics.Walmart's partnership with Rivian for electric delivery vans aimed at reducing carbon emissions and optimizing delivery efficiency.The overarching theme of velocity in business, stressing the importance of speed and adaptability in various industries.The impact of technology and innovation on traditional business practices and consumer behavior.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Joel Guth shares how stepping out from under the Hightower umbrella to become a fully independent RIA opened up a new world of opportunity for his firm Gryphon Financial Partners. He shares how that transition allows them to create a $3B firm designed around turning client problems into opportunities.

Hey everyone, Alex here

Reading by Pastor Teressa Wiley ---   2 Chronicles 28; 2 Kings 16-17   https://www.biblegateway.com/passage/?search=2%20Chronicles%2028%3B%202%20Kings%2016-17&version=ESV&interface=print

In this episode, we cover major updates in the tech and open-source world. OpenAI makes headlines with its $3B acquisition of Windsurf, while the CVE Foundation is officially launched. We discuss key project updates like Spring AI 1.0.0, Jakarta EE 11, and the new Agent Framework by Rod Johnson. Plus, we dive into notable license […]

All Dodgers host Jeff Snider is joined by Justin from Future Dodgers to discuss LA's 2025 draft, which saw the team draft 14 pitchers, four outfielders, two catchers, and a shortstop. Dig into the highs, lows, and in-betweens of this year's draft class for Los Angeles. Share your thoughts in the comments! Tube in all season long! Leave a voicemail or text the Friend of the Show hotline!

Send us a textDr. Amy has played at the highest levels of executive coaching in companies ranging in valuation from $10M to $3B, most achieving a 300%+ top-line growth in 2-3 years. Underneath the business savvy, however, is a deep understanding of psychological and energetic dynamics. Her training in cognitive psychology and her practice as a doctor of Chinese medicine complement spiritual gifts she's had since childhood. Her brain signature also gives Dr. Amy the unique capacity to create transformational shifts in others. She has an undeniable track record of seeing solutions where others can't, removing long-standing blocks and catalyzing massive life changes with ease. Her unique ability to see, know and translate information beyond the physical realms enable her to offer unprecedented clarity and strategic guidance to visionaries, leaders and change makers of the world.https://www.holonexperience.com/Resources:www.SoulAwakeningStore.comwww.claudiumurgan.comclaudiu@claudiumurgan.comhttps://spirituallyinspired.buzzsprout.comSubscribe for more videos! youtube.com/channel/UC6RlLkzUK_LdyRSV7DE6obQSupport the show

Brendan Hargreaves is the Chief Financial Officer (CFO) of Officeworks, a $3B+ business with over 170 stores and 8,000+ team members. Previously, he held senior commercial and financial roles at Qantas ($17B+ revenue), Coles (800+ stores), Cleanaway (5,000+ employees), Village Roadshow, and The Warehouse Group (NZX: WHS, ~$3B market cap). Brendan is also a Director and mentor at the Financial Executives Institute (FEI), supporting the next generation of finance leaders through mentorship and professional development.+++ To support this podcast, check out our some of our sponsors & get discounts:→ $1,000 off Vanta: Your compliance superpower — vanta.com/high→ Get up to 6 months of Notion's Business plan for free with Notion AI included (worth $12K): Go to - https://ntn.so/highflyers & click “Apply Now”If you're keen to discuss sponsorship and partnering with us or recommend future guests, email us at contact@curiositycentre.com today! Join our stable of commercial partners including the Australian Government, Google, KPMG, University of Melbourne and more.  ***CLICK HERE to read show notes from this conversation. Please enjoy!***Follow us on Instagram, LinkedIn or TwitterGet in touch with our Founder and Host, Vidit Agarwal directly hereContact us via our website to discuss sponsorship opportunities, recommend future guests or share feedback, we love hearing how to improve! Thank you for rating / reviewing this podcast on Apple Podcasts and Spotify, it helps others find us and convince guests to come on the show! ***The High Flyers Podcast is described as a "meticulously researched biography" that uncovers the untold stories of remarkable people and companies -- redefining the "high flyer". Launched in 2020, we have ranked in the global top ten podcasts for past two years, with listeners in 27 countries and over 200 episodes released. Excerpts of the podcast have been featured in Forbes, AFR, Daily Telegraph, and showcased at SXSW.200+ guests have joined host, Vidit Agarwal on the show from 15+ countries, including The CEO's of multi-billion dollar companies like Bunnings, Australia Post, Woolworths, Airwallex, Eucalyptus etc; Board Members at Macquarie Bank, ANZ, Reserve Bank etc; Former Prime Minister of Australia; Globally renowned Tech CEO's from Google, Microsoft, Xero etc, Successful Venture Capital and Family Office Investors; CIO's at the world's biggest superannuation funds; Leading Entertainers; Olympic Gold Medal Winning Athletes and interesting minds you wouldn't have heard of that are changing the world. Our parent company, Curiosity Centre is your on-demand intelligence hub for knowledge, connections and growth to achieve your potential, everyday. Join 200,000+ Investors, Founders, Functional Leaders, CEOs and Emerging Leaders. Learn with the world's best and be 1% better everyday at https://curiositycentre.com***   

Vlad Tenev is the Founder and CEO of Robinhood, the greatest story on Wall St of the last decade. In the previous 18 months, Robinhood has increased its net revenue by 58% to nearly $3B; a $500M loss in 2023 turned into a $1.1B profit in 2024. Robinhood's stock is up roughly 4x, lifting their market cap to north of $80B. Today, Robinhood has nine lines of business that do over $100M in revenue.  Agenda:  00:00 – “Tokenization Is The Biggest Innovation in Finance” 03:28 – How Robinhood 4x'd Its Market Cap in 8 Months 06:40 – AI Writes 50% of All Net New Code at Robinhood 10:02 – Why Robinhood Built a Secret ChatGPT for Support 12:11 – The One Customer Type That Transformed the Business 15:29 – “CoreWeave Is Retail's Way Into AI” — The Meme Stock Defense 18:05 – Inside Robinhood's Tokenized Private Shares Product 21:23 – “Capital as a Service” — Vlad's Wild Vision for Startup Fundraising 24:10 – The $100M Revenue Line Vlad Wishes He Could Kill 26:45 – Robinhood Is Building... Cash Delivery Trucks?! 29:55 – “We Were Shipping Nothing”: Vlad on the 2020–2022 Culture Crisis 33:20 – What Line of Business Will Be the Biggest For Vlad in 5 Years Time 35:11 – The One Competitor Vlad Actually Respects 36:55 – From Men's Health to Japanese Toilets: Vlad's Weirdest Quickfire Yet 38:40 – “I Was in the Dumps”: What 2022 Taught Vlad About Resilience 40:00 – Where Robinhood Is Headed: The Next Decade of Financial Infrastructure    

Zach Perret saw a fintech explosion coming—and built the rails before it arrived.On this week's Grit, the Plaid co-founder and CEO retraces his path from building tools for developers to linking the world's largest banks, and how a failed $5.3B acquisition by Visa became a launchpad.He unpacks the pressure of operating in a tightly regulated industry, why rebuilding trust after the deal collapse was harder than expected, and how Plaid is navigating the shift from startup to staple—while staying obsessed with the end user.Links:Connect with ZachXLinkedInConnect with JoubinXLinkedInEmail: grit@kleinerperkins.comLearn more about Kleiner Perkins

Appropriately, I am publishing today's episode from an airport - JFK. This is because it is about the positioning, navigation and timing vertical, specifically about how GPS can be spoofed and jammed, affecting air travel safety. Also appropriately, the recording with Dana Goward, President of Resilient Navigation and Timing Foundation, was occasionally of poor quality. The bandwidth gods have added a bit of ambience reflecting the jamming we talked about. I found Resilient Navigation and Timing Foundation through a Wired article - "A GPS Blackout Would Shut Down the World". Yes, I'm at the podcasting stage where I read Wired articles and just reach out to the people/organisations profiled ;-) Wired used a provocative but truthful title which, perversely, we can be proud of. This is because a vertical in The Geospatial Index is Positioning, Navigation and Timing (PNT) companies. Companies, theory and technology in this vertical have, in Dana's words, produced a silent utility that the whole world has a critical dependence on. Well done to our industry, we are as vital as the water, power, sewer, telecom utilities! The PNT vertical is more well populated than others - 26 companies. There is a flyer in there recently, NextNav. I mentioned them during the episode with Dana and he gave some useful off the cuff commentary on the validity of their offering compared to other more economical solutions. It was a fascinating episode. If you've ever wondered about those maps showing GNSS spoofing and jamming, Dana, a highly accomplished pilot, gave us a lengthy commentary on what they mean and spoke to some geographies where there is a strong risk of this silent utility failing to work properly. A note about running the podcast. It is an experience of talking with some highly accomplished and capable guests. Reading Dana's profile, on gps.gov no less, gives one pause. I got lucky here - I did not read this profile before talking with him. I am glad, because I would have been a deer in the headlights. Some quotes: "...he served as the maritime navigation authority for the United States with 12 different business lines budgeted at over $1.3B/yr, and represented the United States at the International Maritime Organization, International Assn. of Lighthouse Authorities, U.N. anti-piracy working group, and other international forums." He has received a humanitarian award for a coastguard chopper rescue: "...Helicopter Association International's Igor Sikorsky Humanitarian Service Award for his rescue of two fisherman at the height of Hurricane Chantal..." As such, Dana has intimate, professional pilot experience of the risks of GNSS spoofing and jamming. As leader of the maritime navigation authority of the world's largest economy, he has the same degree of knowledge from the perspective of an administrator. This means his call to action as a leader regarding resilience of this silent utility is worth listening to. His charity, Resilient Navigation and Timing Foundation, is also worth joining. One has to wonder when the US will become tired of the embarrassment of being behind the Chinese. Even in the domain of navigation system resilience, the States is behind. I am grateful to Dana for identifying the problem as not being money or technology, but a lack of leadership. He has put himself in front of us as the leader on this issue. Let's listen and study what he has to say, we might find the required actions are straightforward to implement: https://rntfnd.org/.

Episode 624: Neal and Toby unpack Ferrero, the maker of Nutella, acquiring the cereal maker Kellogg in a nearly $3B deal. Then, the Pentagon becomes the largest shareholder for a rare earth mining company. Also, Delta shares jumped 11% signaling traveling is stabilizing. Meanwhile, there's in-fighting in the matcha community that is leading to a shortage. Plus, Varda Space just bagged $187M in funding to make drugs in space.  Meet your local home loan expert at ⁠⁠https://mortgagematchup.com/?utm_source=morning_brew&utm_medium=podcast  Subscribe to Morning Brew Daily for more of the news you need to start your day. Share the show with a friend, and leave us a review on your favorite podcast app. Listen to Morning Brew Daily Here:⁠ ⁠⁠https://www.swap.fm/l/mbd-note⁠⁠⁠  Watch Morning Brew Daily Here:⁠ ⁠⁠https://www.youtube.com/@MorningBrewDailyShow⁠

Welcome back to another episode of Bubba (@bdentrek) and the Bloom (@RyanBHQ). On BATB 259, the guys preview the Week 17 FAAB and review 3B and OF for their 1H positional reviews.

In this powerful episode, Joshua sits down with Gregory Kunkle Jr., a South Texas native and candidate for Congressional District 34, to talk about the urgent environmental and infrastructure crises facing the Rio Grande Valley—and what real solutions might look like.They dive into topics like: • The contamination of the Rio Grande, Arroyo Colorado, and municipal water systems • Mexico's 1.7 million acre-foot water debt under the 1944 Treaty • Air quality, PFAS, arsenic, and the alarming health conditions affecting Valley residents • The rising threat of hurricanes and a failing regional drainage system • And the big question: Why are so many people sick in South Texas?Greg shares his bold vision for transforming the Valley through federal investment in: • Clean drinking water, filtration systems, and desalination • Drainage and flood mitigation—with an estimated $3B price tag and a 20+ year timeline • Nuclear energy, semiconductor manufacturing, and SpaceX partnerships • High-paying tech and healthcare jobs to retain local talentThe conversation ends with a deep dive into Greg's cybersecurity background, the future of AI, and how South Texas can become a national leader in digital innovation—if we act now.

In this post–Fourth of July breakdown, Matty A and Ryan dive into a fiery mix of politics, policy, and financial strategy. From the potential September rate cuts and a sluggish real estate season to massive institutional plays and controversial political shifts, the guys don't hold back. They unpack the good, the bad, and the ugly of Trump's latest bill—bonus depreciation is back, tariffs are rising, and trust is getting tested. Plus, they tackle the Epstein case fallout, Elon Musk's “American Party,” and a bold new baby investment account plan that could shape the next generation's financial future.Timestamps: [00:00] Kicking off with July 4th laughs and family reflections [01:30] Fed's July pause and September rate cut speculation [03:00] The Powell dilemma: lower rates vs. inflation risk [05:00] Real estate slowdown and unconventional buying season [06:45] Best time to be a buyer (despite higher payments) [07:30] Lessons from institutional investors: follow the smart money [08:45] BlackRock's $7.3B play and what it signals [10:00] Risk, timing, and the importance of calculated boldness [11:30] Trump's “Big Beautiful Bill” signed on July 4th – key highlights [12:45] Bonus depreciation, opportunity zones, and spending backlash [14:00] Tariff revenues hit record highs—what it means [17:30] Trump's tariff timeline, market reactions, and potential trade deals [20:00] Semiconductor, copper, pharma tariffs, and BRICS crackdown [22:00] Banning foreign adversaries from buying U.S. farmland [23:30] Epstein case fallout: No client list, public outrage [25:00] The erosion of trust in Trump's cabinet over unfulfilled promises [28:00] The frustrating lack of transparency and accountability [30:00] Trump's Ukraine funding flip and political ripple effects [32:00] Elon Musk's “American Party” and the risk of splintering votes [34:00] Baby Bonds! $1,000 government-funded investment accounts [35:30] Building generational wealth with small, consistent contributions [36:00] Final thoughts, Napa mastermind promo, and closing cheersWhat You'll Learn:Why September may be a pivotal month for interest rate cutsHow smart institutional capital is positioning in real estateWhat Trump's new bill means for investors (the good & the ugly)How tariffs are reshaping global trade and impacting U.S. marketsWhy Epstein file backlash could cost Trump political capitalHow the new “Baby Bonds” program could build future wealthNotable Quotes:“Fortune favors the bold — but the smart bold.” – Matty A“Institutional capital doesn't chase trends… they create them.” – Ryan Breedwell“If it was easy, everybody would do it. But that's not when wealth is made.” – Matty A“Tariffs work if you want to balance the trade scale… it's not emotional, it's strategic.” – Ryan BreedwellCalls-to-Action: Text XRAY to 844.447.1555 – Get your financial x-ray Text DEALS to 844.447.1555 – Find off-market investment opportunities Follow @officialmattya on social Visit Shop.MillionaireMindcast.com – Mindset, Money & Motivation gear Want to mastermind in Napa with top real estate investors? Text NAPA to 844.447.1555 to claim your seat (limited spots)

Grant reacts to dominance from the Brewers pitching staff- and asks if recent performances from Woodruff and Miz necessitate a move for a real bat at 3B or SS. See omnystudio.com/listener for privacy information.

The boys are back recapping the player movement from the NFBC Main Event Week 14 FAAB. Plus we look at the possible first round of 2026 draftsNormal Contest Spending CoverageLowest spend per team, but still a lot of activityMost Money Spent2 Players over $1,0004 Players over $500Henriquez - 2 saves and a win in 3 IP last week with 5 Ks.  Not much else out there which likely drove up the price to the $70 level on avg.HSK - 1 game then hurt againCantillo - sent down to AAA to stretch out in June, built up to 3.1 IP, how long until he gets to 5 IP a start?Colson Montgomery - .625 BABIP in first 3 MLB games.  Hit .218 with a 34% K-rate at his 2nd season at AAA Widely added players (over 15 leagues)Max Muncy Jr. - Gelof call-up and Urias IL shifts him to 3B, but does Andujar eat into his PT?  Kurtz, Muncy, Andujar haven't been on the field at the same time this yearJordan Hicks - Sunday save tax + every Trade Deadline article mentioning Aroldis as the likeliest candidate to be tradedWill Benson - 7 game week at GABP vs. all RHP - but Rockies sent Dollander down :-(Schneider - Had started 7 straight including vs. 4 RHP last week and moved up to 5th in the order.  Gimenez to the IL, Bo and Vlad have been banged up.  Are Loperfido and Wagner threats to his PT?Brooks Baldwin - played in 6 of the 7 games since getting recalled (all in CF) and moved up as high as cleanup in the order - does he stick when LuBob returns?Harrison Bader - Willi has shifted to the infield which is good for Bader's PTStarting Pitchers - Gusto, Allen, Burrows, Fitts, SWR, Colin ReaStashes - Pablo Lopez, Nestor, Zebby, Francisco Alvarez⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠PullHitter merch is here! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Welcome to the PullHitter Podcast, your destination for actionable resources and tools to grind your way to ultimate fantasy baseball success.Support my work and join the Pull Hitter Patreon:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠-Access to lively Discord with highly active members sharing player evaluations, draft boards and strategies..get a leg up on your league mates!-Player Breakdowns series in audio and video form-Draft recaps from me-additional Launch Angle episodes-additional Guest episodes-ad free listening-Much more!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://patreon.com/user?u=32383693&utm_medium=clipboard_copy&utm_source=copyLink&utm_campaign=creatorshare_creator&utm_content=join_link⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on twitter: @pullhitterpod ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twitter.com/PullHitterPod⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ @deadpullhitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twitter.com/deadpullhitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Email : pullhitterpodcast@gmail.com Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠pullhitter.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠My link tree with all of my links in one spot:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://linktr.ee/pullhitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Also check out me cohosting the Launch Angle Podcast with Jeff Zimmerman and Rob Silver!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://anchor.fm/robe

Reading by Pastor Teressa Wiley ---   2 Kings 15; 2 Chronicles 26   https://www.biblegateway.com/passage/?search=2%20Kings%2015%3B%202%20Chronicles%2026&version=ESV&interface=print

Joe's Premium Subscription: www.standardgrain.comGrain Markets and Other Stuff Links-Apple PodcastsSpotifyTikTokYouTubeFutures and options trading involves risk of loss and is not suitable for everyone.0:00 No Trade Deals, Markets Tumble2:07 OBBB and Farmers3:42 Tariff Deadlines6:38 Drought/Weather Update8:23 Record Corn Export Program Possible?9:50 Russia Slashes Wheat Export Tax10:57 Flash Sales

Reading by Deborah Volosin ---   2 Kings 14; 2 Chronicles 25   https://www.biblegateway.com/passage/?search=2%20Kings%2014%3B%202%20Chronicles%2025&version=ESV&interface=print

Reading by Deborah Volosin ---   2 Kings 12-13; 2 Chronicles 24   https://www.biblegateway.com/passage/?search=2%20Kings%2012-13%3B%202%20Chronicles%2024&version=ESV&interface=print

Poilievre has never been further from the spotlight. After years of headlines and media attention, even Poilievre's staunchest supporters have stopped talking about him. Is this the beginning of the end for Poilievre or is he gearing up for a comeback? Host: Noor AzriehCredits: James Nicholson (Producer), Lucie Laumonier (Associate producer and Fact Checking) Tristan Capacchione (Audio Editor and Technical Producer), max collins (Director of Audio), Jesse Brown (Editor)Guest: Arno KopeckyAdditional music by Audio Network Further reading: Pierre Poilievre might be cooked – Canada's National ObserverPierre Poilievre has dropped out of the spotlight. What happens when he comes back? – The Toronto StarMark Carney, and the return of the Progressive Conservative – The Globe & MailAlberta posts surplus of $8.3B in 2024-25 fiscal year – CBCHotel owners in Manitoba charged in labour trafficking investigation – CTV News Sponsors:oxio: Head over to canadaland.oxio.ca and use code CANADALAND for your first month free! Douglas: Douglas is giving our listeners a FREE Sleep Bundle with each mattress purchase. Get the sheets, pillows, mattress and pillow protectors FREE with your Douglas purchase today. Visit douglas.ca/canadaland to claim this offer If you value this podcast, support us! You'll get premium access to all our shows ad free, including early releases and bonus content. You'll also get our exclusive newsletter, discounts on merch at our store, tickets to our live and virtual events, and more than anything, you'll be a part of the solution to Canada's journalism crisis, you'll be keeping our work free and accessible to everybody. You can listen ad-free on Amazon Music—included with Prime. Hosted on Acast. See acast.com/privacy for more information.

Council is about to start its summer break, but not before making a bunch of decisions that could shape the future of Edmonton. Infill and the zoning bylaw changes are the big item again this week, but we also talk about the Downtown CRL extension, the Winspear Centre expansion, road widening, a proposal for free parking, and more.Here are the relevant links for this episode:CRLEdmonton council extends Downtown CRL, ending two days of debateWinspear CentreOctober 2024: Winspear expansion in final push for fundraising and constructionCity Council - March 18, 2025Bike skills parkEdmonton approves seven-acre mountain bike facility in river valleyParking ban towingCity approves return of tow trucks during parking bansDowntown district energyNews Release: City Council approves growth of Downtown District Energy InitiativeInfill and zoning bylawHere are the proposed changes to Edmonton's zoning bylaw set for debate this week'Absolute mess': Public put on hold as city council wades through marathon zoning sessionEdmonton city councillor's infill moratorium attempt fails for legal reasonsEdmonton councillors blast Cartmell for failed infill motionZoning bylaw debate poses some thorny issues for Edmonton councilFree parkingFree parking plan aims to revive Edmonton's coreRoad wideningEdmonton looking to widen some roads due to growing traffic congestionRapid fireFrats and sororities, evicted by U of A, struggle to find housing in GarneauEx-UCP MLAs reviving Alberta's Progressive Conservative PartyAlberta posts surplus of $8.3B in 2024-25 fiscal yearElection projectWhat issues do you care about as you consider who to vote for in the 2025 municipal election, and why?A progress report on Taproot's election projectWhat we heard at our election listening sessionsThis episode is brought to you by Park Power, your friendly, local utilities provider (and title sponsor of Taproot's Regional Roundup). Park Power offers electricity, natural gas, and internet to homes, businesses, and farms throughout Alberta. Learn more at parkpower.ca.Speaking Municipally is produced by Taproot Edmonton, the most reliable source of intelligence about what's happening in the Edmonton region. Through curiosity-driven original stories, tailored and useful newsletters, a comprehensive and innovative events calendar, and thought-provoking podcasts, we inform, connect, and inspire a more vibrant, engaged, and resilient Edmonton region.Sign up to get The Pulse, our weekday news briefing. It's free! ★ Support this podcast ★

Send JD a text message and be heard!PIRATES 6 wins in a row!!! Change managers and now 38-50.  @kettle.whistle.radio is going crazy in the #steelcity do they even call that anymore?  @nyknicks fans how we feeling about #mikebrown given the keys to the kingdom?  @companyadjace @realmaxjarvis @call_me_tca_prez @lrt_network @rho212 @brianbarnaby @robparker1980 @lbrolsky @i_need_a_sports_iv @cpd94_mk @paddy_bailey & @donna.fender first off congrats @_secretly_batman on starting a @youtube series on your injury recovery.  @anthonyyacc great debate on @jjwatt vs @tjwatt90 who would you take?   Paddy brought up great point.  Play different positions.  @mets 3-14 streak after losing first game of #doubleheader to @brewers & discussed @giancarlo818 would make a great DH.  Sorely needed and an owner with money to burn.  @yankees need a 3B.  #jazzchisholmjr better at 2B.  @jaymahanti on tomorrow to talk all things about the team in #queens  & #sportstrivia at the finish.All sports. One podcast. (even hockey) PODCAST LINK ON ITUNES: http://bit.ly/JDTSPODCAST

siman 319:3B in Chelek Gimmel- Hilchos Shabbos by Rabbi Tzvi Thaler

From $7 to 42 properties—Vinney's blueprint is all about team.

Welcome to Omni Talk's Retail Daily Minute, sponsored by RetailClub and Mirakl. In today's Retail Daily Minute:Nintendo exits Amazon's U.S. storefront amid a third-party seller dispute, skipping the Switch 2 launch and leaving American shoppers out of the release.France clamps down on ultra-fast fashion, introducing new legislation aimed at Shein and Temu to address sustainability and labor concerns.Home Depot strikes a $4.3B deal to acquire GMS, expanding its contractor-focused business through its SRS Distribution arm as it doubles down on the Pro segment.The Retail Daily Minute has been rocketing up the Feedspot charts, so stay informed with Omni Talk's Retail Daily Minute, your source for the latest and most important retail insights. Be careful out there!

Charismatic and respected eyecare industry legend, Jim McGrann, joins OWA Talks to share his passion for the industry and shed a light on the benefits of ‘spreading your wings' in optical. About the guest:Jim McGrann is an engaging, decisive and adaptable leader with a demonstrated history of delivering results in the healthcare, insurance, technology, supply chain and consulting industries. Mr. McGrann is an experienced CEO with a passion for helping businesses win in the marketplace while growing profitably and achieving change amid order, and order amid change.  Mr. McGrann possesses the ideal mix of business skills, technology expertise and creativity to lead in today's rapidly evolving marketplace.  He has been a C-Level executive for 25+ years and serves on both business and not-for-profit boards of directors.Mr. McGrann is the CEO of Advancing Eyecare, a leader in the eyecare instrumentation marketplace established to offer the best products and service solutions in the ophthalmic equipment industry. Prior to joining Advancing Eyecare, Mr. McGrann was the Chairman & CEO of PECAA | Healthy Eyes Advantage a solutions company that empowers independent eye care professionals to succeed in the rapidly evolving optical industry. This business was sold to VSP Vision in September 2022.Prior to joining Healthy Eyes Advantage, Mr. McGrann was the President & CEO of VSP Global (now VSP Vision), a $5.3B vertically integrated healthcare organization with the mission of helping people see.  He successfully navigated the needs of a complex set of stakeholders, including 83M customers, 60K clients, 37K doctors, 6K global employees & numerous business partners including fashion houses, lens & lab, software and eyewear companies. From December 2008 to November 2011, before becoming CEO of VSP Global, Mr. McGrann served as VSP Global's President of Eyefinity, the largest practice management and electronic health record company in the Optical industry serving 25K doctors, VSP Global's Chief Technology Officer and President of VSP Vision Care, the largest healthcare company in the world (by membership) providing vision benefits to 83M consumers (including 1 in 4 Americans).  From December 2011 to September 2015, while President of VSP Vision Care, Mr. McGrann focused on winning in the marketplace and the business grew by $1.02B (34%) and 23.7M members (42%) while delivering record EBITDA and NIBT. He also led the creation and strategic development of VSP Global's innovation lab, The Shop. Mr. McGrann leveraged techniques such as design thinking, user-centered design and nexus management to successfully launch The Shop in a three-month period.While President of VSP Vision Care, Mr. McGrann was Chairman of the Board for the National Association of Vision Care Plans (NAVCP). The NAVCP is the national association established to act as the unified voice representing the managed vision care industry. Mr. McGrann was elected as Chairman by his peers at competing organizations.Like this episode? Please subscribe and share!iTunes | Spotify | Overcast | iHeartRadio | AmazonConnect with the OWA:Website | LinkedIn | Instagram | Facebook

In this episode, Alex speaks with Jeff Zwiefel, former President & COO of Life Time, about scaling the business from $139M to $2.3B in revenue and navigating multiple private equity exits and IPOs. Jeff shares how a people-first culture and rigorous training enabled long-term, sustainable growth in a competitive industry.Jeff discusses why private equity firms often miss the mark by focusing only on KPIs and financials, instead of investing in leadership, culture, and succession. He explains Life Time's unique "casting" approach to hiring, their internal university for training, and the importance of empowering GMs as mini-CEOs of their locations.The conversation also covers trends in the health and wellness sector, the rise of personalized longevity services, and how private equity can unlock new value in this rapidly evolving space.

Want Sam's playbook to turn ChatGPT into your executive coach? Get it here: https://clickhubspot.com/etb Episode 722: Sam Parr ( https://x.com/theSamParr ) sits down with Mike Novogratz ( https://x.com/novogratz ) about risk tolerance and coming back from massive losses. — Show Notes: (0:00) Mike's first million (8:37) Starting Fortress (13:55) $30M to $2.3B (25:28) Operating system for life (35:41) Being early on crypto (40:26) Risk tolerance — Links: • Fortress - https://www.fortress.com/ • Galaxy - https://www.galaxy.com/ • Business Untitled - https://www.youtube.com/@BusinessUntitled — Check Out Shaan's Stuff: • Shaan's weekly email - https://www.shaanpuri.com • Visit https://www.somewhere.com/mfm to hire worldwide talent like Shaan and get $500 off for being an MFM listener. Hire developers, assistants, marketing pros, sales teams and more for 80% less than US equivalents. • Mercury - Need a bank for your company? Go check out Mercury (mercury.com). Shaan uses it for all of his companies! Mercury is a financial technology company, not an FDIC-insured bank. Banking services provided by Choice Financial Group, Column, N.A., and Evolve Bank & Trust, Members FDIC — Check Out Sam's Stuff: • Hampton - https://www.joinhampton.com/ • Ideation Bootcamp - https://www.ideationbootcamp.co/ • Copy That - https://copythat.com • Hampton Wealth Survey - https://joinhampton.com/wealth • Sam's List - http://samslist.co/ My First Million is a HubSpot Original Podcast // Brought to you by HubSpot Media // Production by Arie Desormeaux // Editing by Ezra Bakker Trupiano

Reading by Pastor Teressa Wiley ---   1 Kings 22; 2 Chronicles 18   https://www.biblegateway.com/passage/?search=1%20Kings%2022%3B%202%20Chronicles%2018&version=ESV&interface=print

In this week's Fast Five Podcast, sponsored by the A&M Consumer and Retail Group, Simbe, Mirakl, Ocampo Capital, Infios, and ClearDemand, we deep dive into Whatnot, the live streaming shopping app that hit $3B in sales selling trading cards, sneakers, and collectibles. We explore whether this QVC-meets-Twitch model can expand beyond niche markets and why video commerce is finally taking off in America. Timestamps: 8:28 - What is Whatnot? 9:47 - US vs China video commerce 10:44 - Niche vs mass market potential 13:05 - eBay 2.0 comparison 14:30 - Platform distribution challenges Catch the full episode here: https://youtu.be/3lsaTBvBuMs #Whatnot #LiveShopping #VideoCommerce #CollectiblesTrading #SocialCommerce #LiveStreaming

Stephen Petasky is the founder and CEO of The Luxus Group, a hospitality and development firm specializing in luxury vacation homes, global restorations, and high-end resort communities. Over nearly two decades, he's raised more than $100 million, facilitated 20,000 vacations, and partnered with brands like Four Seasons to deliver premium lifestyle experiences through real estate. His business journey spans from fractional home ownership to international development, all driven by a passion for design, family travel, and scalability.     Make sure to download our free guide, 7 Questions Every Passive Investor Should Ask, here. Key Takeaways Stephen started Luxus by solving his own problem—traveling with young kids—and turned that into a $100M global vacation home portfolio. Raising capital gets easier when the investment includes a dual purpose, like lifestyle use alongside financial return. Scaling a business requires building it “back to front”—start with the exit goal, then reverse engineer every step. Real estate and development success takes patience; some ventures took 7–10+ years to turn profitable. Subject matter expertise becomes a valuable asset after years of refinement, leading to higher-impact, lower-risk projects.     Topics How a Personal Travel Need Became a Syndicated Real Estate Venture Started Luxus to create a family-friendly alternative to hotels or inconsistent vacation rentals. Solved the problem of predictability, comfort, and flexibility by imagining ownership of 30 homes—then invited others to co-invest. Raised $3.5M to purchase three homes; word-of-mouth demand led to $100M+ raised and 50 properties acquired. Dual-Purpose Investing: Lifestyle + Returns Investors received lifestyle benefits—discounted nightly rates—alongside capital preservation. These vacation privileges created real financial savings, boosting total return beyond simple IRR metrics. Stephen compares the model to a “golf club that sells at the end”—with liquidity and upside built in. How to Make Raising Capital Easier Dual-purpose investments or vendor-aligned capital (e.g., landowners or contractors investing) make raises more compelling. Giving investors experiential or operational upside increases buy-in—even when the financial returns are moderate. Partnerships built on aligned interests are more resilient over time. Scaling With Clarity and Hindsight Luxus' new business model was built “back to front,” starting with a $100M valuation target and working backward to day one. Planning for bottlenecks—legal, financial, tech, or operational—can reduce future breakdowns. AI tools now help model scalable pathways and highlight structural weak points before launch. New Ventures: Management, Development, and Restorations Luxus now manages luxury short-term rentals it doesn't own, applying hotel-like service and strategy. Stephen is a core partner in the Four Seasons Private Residences Las Vegas ($1.3B sellout). The company also restores centuries-old Tuscan estates for North American and European clients—12 years in, with a waitlist.    

In this episode of Abundance Thursdays, Vinney Smile Chopra and Gualter Amarelo tackle the real reason most businesses stall out—team structure. Vinney, a real estate legend who's raised over $220 million and owns $1.3B in assets, reveals his top 10 hacks for building a team that scales your business, boosts investor trust, and fuels sustainable growth.   Here's what you'll learn:

Reading by Karen Griffin ---   1 Kings 16; 2 Chronicles 17   https://www.biblegateway.com/passage/?search=1%20Kings%2016%3B%202%20Chronicles%2017&version=ESV&interface=print

Ryan Sachtjen is the Co-founder and CEO of Threeflow, building software for employee benefits brokers and insurance carriers.We start with a deep dive into the nearly $2 trillion dollar employee benefits market, including the structural issues that actually give the smallest companies the most leverage.We also talk about insurance more broadly, AI opportunities in insurance, lessons from kickstarting a marketplace doing nearly $3B in volume, when his wife got cancer two months after closing Threeflow's seed round, and how his co-founders adjusted to support him.Special thanks to Bolt for supporting this episode! Join the world's largest hackathon - up to $1m in prizes. Sign-up here.Timestamps:(3:57) Threeflow: B2B benefits marketplace(5:50) How the benefits industry works(9:20) The importance of brokers in insurance(12:32) Benefits broker software stack(15:36) How to make money in employee benefits(21:11) Ways to compete in insurance(26:34) How AI is changing insurance(31:01) What its like to be an insurance broker(35:37) Starting ThreeFlow in 2016 pre-LLMs(40:13) The 128 day walk through Europe before Threeflow(44:47) When his wife was diagnosed with breast cancer(50:23) Advice for founders on surviving large personal events(52:46) Threeflow's unorthodox Seed round(59:46) How to vet your investors(1:04:14) Why insurance brokers exist(1:05:08) How to build a marketplace on top of Vertical SaaS(1:10:53) Choosing a marketplace entry point(1:15:05) $2.5B in premium volume on Threeflow workflows(1:26:39) Importance of supply side volume in a marketplace(1:31:21) Fundraising without a formal process(1:33:03) Hiring for “just get stuff done”(1:36:22) AI opportunities in insurance(1:41:05) Building software in insurance(1:44:56) Tactics for running a distributed team(1:49:04) Creating your own playbooksReferencedTry ThreeflowCareers at ThreeflowFollow RyanLinkedIn: https://www.linkedin.com/in/ryansachtjen/Follow TurnerTwitter: https://twitter.com/TurnerNovakLinkedIn: https://www.linkedin.com/in/turnernovakSubscribe to my newsletter to get every episode + the transcript in your inbox every week: https://www.thespl.it/

Last week, Guild Mortgage made headlines with its $1.3 billion acquisition by Bayview Asset Management. This week, Diego welcomes Terry Schmidt, the CEO of Guild Mortgage, to talk about how Guild plans to innovate, scale and deepen customer loyalty, without losing its retail identity. Terry and Diego dive into the synergy between Guild's distributed retail model and Bayview's $700 billion servicing portfolio. They also talk about Guild's investment in AI and tech, ongoing M&A ambitions, and how cultural alignment and local relationships will still be their secret weapon. Here's what you'll learn: Why Bayview's acquisition of Guild was a strategic move, not just financial. Guild's "customers for life" strategy delivers strong recapture performance. How Bayview's capital unlocks new proprietary loan products for Guild. Cultural alignment is central to Guild's M&A and growth strategy. AI and tech will play a major role in Guild's next chapter. Related to this episode:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Guild Mortgage Bayview to buy Guild for $1.3B in cash, taking lender private | HousingWire Terry Schmidt  | LinkedIn ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠HousingWire | YouTube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Enjoy the episode! The Power House podcast brings the biggest names in housing to answer hard-hitting questions about industry trends, operational and growth strategy, and leadership. Join HousingWire president Diego Sanchez every Thursday morning for candid conversations with industry leaders to learn how they're differentiating themselves from the competition. Hosted and produced by the HousingWire Content Studio. Learn more about your ad choices. Visit megaphone.fm/adchoices

This week, we have some updates on Trump's appeal in the E. Jean case and the case against Alex Jones brought by the families of the Sandy Hook massacre. Trump pardons are costing American taxpayers over $1.3B. The DoJ is asking for life in prison for Edward Kelley for the January 6th insurrectionist's FBI murder plot. Plus, we have some comings and goings, and a little more on the Proud Boys' lawyer Augustus Sol Invictus.Thank you, CB Distillery.Use promo code CLEANUP at CBDistillery.com for 25% off your purchase.Specific product availability depends on individual state regulations.  Allison Gillhttps://muellershewrote.substack.com/https://bsky.app/profile/muellershewrote.comHarry DunnHarry Dunn | Substack@libradunn1.bsky.social on BlueskyWant to support this podcast and get it ad-free and early?Go to: https://www.patreon.com/aisle45podTell us about yourself and what you like about the show - http://survey.podtrac.com/start-survey.aspx?pubid=BffJOlI7qQcF&ver=short

Reading by Pastor Teressa Wiley ---   1 Kings 15; 2 Chronicles 13-16   https://www.biblegateway.com/passage/?search=1%20Kings%2015%3B%202%20Chronicles%2013-16&version=ESV&interface=print

According to Bloomberg reporting, Meta Platforms (META) discussed a possible acquisition of video startup Runway as the company seeks to expand its presence in the tech space. Jenny Horne looks at META's continued push into AI as Mark Zuckerberg's company recently completed its $14.3B investment in Scale AI. Jenny also shares Citi's price target hike to $803 from $690. Later, she cites NHTSA reports that it will be probing videos of Tesla's (TSLA) Robotaxi debut.======== Schwab Network ========Empowering every investor and trader, every market day.Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – https://twitter.com/schwabnetworkFollow us on Facebook – https://www.facebook.com/schwabnetworkFollow us on LinkedIn - https://www.linkedin.com/company/schwab-network/About Schwab Network - https://schwabnetwork.com/about

Dr. Shaalan Beg and Dr. Kristen Ciombor discuss practice-changing studies in GI cancers and other novel treatment approaches that were presented at the 2025 ASCO Annual Meeting. Transcript Dr. Shaalan Beg: Hello, I'm Dr. Shaalan Beg, welcoming you to the ASCO Daily News Podcast. I'm a medical oncologist and an adjunct associate professor at UT Southwestern Medical Center in Dallas, Texas. There were some remarkable advances in gastrointestinal cancers that were presented at the 2025 ASCO Annual Meeting, and I'm delighted to be joined by Dr. Kristen Ciombor to discuss some exciting GI data. Dr. Ciombor is the Ingram Associate Professor of Cancer Research and a co-leader of Translational Research and the Interventional Oncology Research Program at the Vanderbilt Ingram Cancer Center. Our full disclosures are available in the transcript of this episode. Dr. Ciombor, it's great to have you on the podcast today. Dr. Kristen Ciombor: Thanks, Dr Beg. It's great to be here. Dr. Shaalan Beg: Alright, let's kick it off. Big year for GI cancers. We'll start off with LBA1. This was the ATOMIC study sponsored by NCI and the National Clinical Trials Network (NCTN) and the Alliance group. This is a randomized study of standard chemotherapy alone or combined with atezolizumab as adjuvant therapy for stage III mismatch repair deficient colorectal cancer. Dr. Kristen Ciombor: I think this study was really definitely practice-changing, as you can tell because it was a Plenary. But I do have some concerns in terms of how we're actually going to implement this and whether this is the final answer in this disease subtype. So, as you said, the patients were enrolled with stage III resected mismatch repair deficient colon cancer, and then they were randomized to either modified FOLFOX6 with or without atezolizumab. And that's where it starts to become interesting because not many of us give FOLFOX for 6 months like was done in this study. Obviously, the study was done over many years, so that was part of that answer, but also the patients received atezolizumab for a total of 12 months. So the question, I think, that comes from this abstract is, is this practical and is this the final answer? I do think that this is practice-changing, and I will be talking to my patients with resected mismatch repair deficient colon cancer about FOLFOX plus atezolizumab. I think the big question is, do these patients need chemotherapy? And can we do a neoadjuvant approach instead? And that's where we don't have all the answers yet. Dr. Shaalan Beg: Yeah, but it has been great to see immunotherapy make its way into the adjuvant space after having made such a big impact in the metastatic space, but still some unanswered questions in terms of the need for chemotherapy and then the duration of therapy, which I guess we'll have to stay tuned in for the next couple of years to to get a lot of those questions answered. Dr. Kristen Ciombor: Yeah, but a big congratulations to the study team, to the NCTN, the NCI. I mean, this is really a great example of federally funded research that needs to continue. So, great job by the study team. The DFS 10% difference is really very large and certainly a practice-changing study. Dr. Shaalan Beg: Yeah, and and sticking with colon cancer, and and this another federally funded study, but this time funded by a Canadian cancer clinical trials group was LBA3510. This is the CHALLENGE study. It's a randomized phase 3 trial of the impact of a structured exercise program on disease-free survival for stage III or high-risk stage II colon cancer. This study got a lot of buzz, a lot of mainstream press coverage, and a lot of discussions on what that means for us for the patients who we're going to be seeing next week in our clinic. What was your takeaway? Dr. Kristen Ciombor: Yeah, this is a really interesting study, and I was so glad to see it presented because this partially answers one of the questions that patients always have for us in clinic, right? You know, once they've completed their standard chemotherapy and surgery, what else can they do to help prevent recurrence? And so we've always known and sort of extrapolated that healthy lifestyle habits are good, but now we have data, particularly in these patients. Most of them were stage III colon cancer patients, those had high-risk stage II cancer. And basically, the goal was to increase their physical activity by at least 10 MET hours per week. So, my big question, of course, as I came into this presentation was, “Okay, what does that mean exactly? How does that translate to real life?” And really what the author presented and explained was that basically most patients could hit their target by adding a 45- to 60-minute brisk walk 3 to 4 times a week. So I think this is very approachable.  Now, in the confines of the study, this was a structured exercise program, so it wasn't just patients doing this on their own. But I do think kind of extrapolating from that, that this is very achievable for most patients. And not only did this prevent recurrence of their prior cancer, but actually the rate of new primary cancer diagnoses, was less, which is really interesting, especially in the breast and prostate cancer. So this was a really interesting, and I think practice-changing study as well, especially given that this is something that most patients can do. Dr. Shaalan Beg: Yeah, and there was a lot of discussion in the hallways after the presentation in terms of how this really changes our existing practice because most folks already recommend exercise as a way for improving outcomes in cancer patients. So we've already been doing that. Now we have some data on how much it can impact the benefit. But there was some discussion about what the actual degree of impact was. There was a drop-off rate in terms of how long folks were able to stick with this exercise regimen. But you've seen this in clinic when someone have their surgery, they have their chemotherapy, they've been so intimately involved with the oncology world, with the oncology practice, and they somehow feel that they're being let loose into this mean, angry world without any guidance and they're looking for something to do. “What more can I do in terms of my lifestyle?” And then here we have very solid data, as solid as can be for an intervention like exercise, showing that there is an impact and you can give a prescription for exercise when someone wraps up their chemotherapy for colon cancer, thanks to the study. Dr. Kristen Ciombor: Yeah. It was a great study. Dr. Shaalan Beg: Moving to gastroesophageal cancer, another late-breaking abstract. This is LBA5. The MATTERHORN trial was a phase 3 trial of durvalumab plus FLOT for resectable GE junction and gastric cancer. And again, another area where immunotherapy has made an impact, and here we're seeing it move closer for earlier-stage disease. What was your take-home for the MATTERHORN trial? Dr. Kristen Ciombor: Yeah, so this study looked at neoadjuvant perioperative durvalumab plus our current standard chemotherapy of FLOT versus placebo plus FLOT. And this was a large study, almost 1,000 patients were randomized. And the primary endpoint was event-free survival, and it was definitely met in favor of the D + FLOT arm, as Dr. Klempner discussed after Dr Janjigian's presentation. I do think there are still some unanswered questions here. Overall survival is not yet mature, so we do have to wait and see how that shakes out. But it's very interesting and kind of is reflective of what, as you said, we're looking at earlier and earlier lines of therapy, particularly with immunotherapy, in these GI cancer spaces. So it makes a lot of sense to test this and and to look at this. So the toxicity was pretty similar to what we would expect. Primary endpoint was met, but again, we'll have to wait and see what the survival data looks like. Dr. Shaalan Beg: Yeah, and in oncology, we know, especially for treatment that does add additional cost, it does add additional potential toxicity that we want to see that overall survival nudged. I did see some polls on social media asking folks whether their practices changed from this, and I think the results were favoring adding durvalumab for this group of patients but understanding that there are caveats to the addition of treatments and the eventual FDA approval in that indication as well. Dr. Kristen Ciombor: Exactly. I completely agree with that. Dr. Shaalan Beg: All right. How about we stick with gastroesophageal cancer? LBA4002 was trastuzumab deruxtecan versus ramucirumab plus paclitaxel for second-line treatment in HER2-positive unresectable or metastatic gastric cancer or GE junction cancer. This was the DESTINY-Gastric04 study. And again, antibody-drug conjugates making a big impact across different diseases. And here we have more data in the HER2-positive gastric cancer space. Your thoughts on this study? Dr. Kristen Ciombor: Yeah, so this is a really important space in gastroesophageal cancer because the HER2 positivity rate is fairly high as compared to some of our other tumor types. So, I do think one of the important things was that patients did have biopsy confirmation of HER2 status, which was very important, and then they were randomized to either T-DXd versus the kind of second-line standard of ramucirumab-paclitaxel. So this was a great practical study and really answers a question that we had for a while in terms of does anti-HER2 therapy in the second-line really impact and improve survival. So we did see a statistically significant improvement favoring T-DXd. I do think it's always important to look at toxicity, though, too. And there was about almost 14% rate of interstitial lung disease, which of course is the most feared toxicity from some of these antibody-drug conjugates, especially T-DXd. So I do think it's important to keep that in mind, but this is definitely a great addition to the armamentarium for these HER2-positive patients. Dr. Shaalan Beg: And pancreas cancer was on the stage after a very long time with a positive clinical trial. This is Abstract 4006. These were preliminary results from a phase 2 study of elraglusib in combination with gemcitabine/nab-paclitaxel versus gemcitabine/nab-paclitaxel alone for previously untreated metastatic pancreas cancer. This is a frontline clinical trial of gemcitabine/nab-paclitaxel plus/minus the study drug. There were other cohorts in this study as well, but they reported the results of their part 3B arm. And great to see some activity in the pancreas space. And your thoughts? Dr. Kristen Ciombor: Yeah, we definitely need better treatments in pancreas cancer. This was a very welcome presentation to see. The elraglusib is an inhibitor of GSK-3beta, and it's thought that that mediates drug resistance and EMT. And so this is, I think, a perfect setting to test this drug. So patients basically were randomized. Patients with metastatic pancreas cancer were randomized 2: 1 to gemcitabine/nab-paclitaxel plus or minus this elraglusib. So, what we saw was that overall survival was better with the addition of this new drug. And overall, not only the 1-year overall survival, but also median overall survival.  The thing that was interesting, though, was that we saw that the overall survival rates were 9.3 months with the combination versus 7.2 months with just gemcitabine/nab-paclitaxel. And that's a little bit lower than we've seen in other studies. So, not sure what was going on there. Was it the patients that were a bit sicker? Was it a patient selection, you know, thing? I'm not really sure how to explain that so much. Also, the toxicity profile was much higher in terms of visual impairment, with over 60% of patients being treated with the combination versus 9% with gemcitabine/nab-paclitaxel. So these were mild, grade 1 and 2, but still something to be cautious about. Dr. Shaalan Beg: And especially with this being a phase 2 trial, making sure that in a larger study we're able to better evaluate the toxicity and see if the control arm in the larger confirmatory study performs differently will be really important before this compound makes it to the clinic in our space. But very exciting to see these kinds of results for pancreas adenocarcinoma. Dr. Kristen Ciombor: Yeah. Dr. Shaalan Beg: We've talked, it seems, a couple of times on this podcast about the BREAKWATER clinical trial. We did hear PFS and updated OS data, updated overall survival data on first-line encorafenib plus cetuximab plus modified FOLFOX6 for BRAF-mutated colorectal cancer. This was LBA3500. And eagerly anticipated results – we have all previously heard the progression-free survival results – but here we heard updated overall survival results, and very well-received study it seemed from the audience that time. So what are your takeaways on the updated results for BREAKWATER? Dr. Kristen Ciombor: In my opinion, this was one of the most practice-confirming studies. As you mentioned, we've already seen some of the preliminary data of BREAKWATER at prior meetings. But really what was particularly impactful for me was the median overall survival with the BREAKWATER regimen. So, again, patients received FOLFOX, encorafenib cetuximab in the first line if they had BRAF-mutated V600E-mutated colorectal cancer. And the median PFS was 12.8 months, which was actually really remarkable in this traditionally very aggressive, poor prognosis subtype of tumors. So, by seeing a median overall survival of 30.3 months was just incredible, in my opinion. Just a few years ago, that was considered the median overall survival for all comers for metastatic colorectal cancer. And we know the median overall survival was more in the less than 12 months range for BRAF. So this was incredibly impactful, and I think should be absolutely practice-changing for anyone who is eligible for this regimen.  I think again, where the practice meets the study is what's kind of important to think about too, how long did patients get FOLFOX, and certainly it adds toxicity to add a BRAF-targeted regimen on top of FOLFOX already. So, one of the other interesting things about the study, though, was that even though it didn't complete treatment, they actually did look at encorafenib/cetuximab alone and in the first line without chemotherapy. And those preliminary results actually looked okay, especially for patients who might not be able to tolerate chemotherapy, which we certainly see in practice. So, overall, definitely more data. And I agree that it's certainly practice-changing. Dr. Shaalan Beg: And it completely, as you mentioned, changes the outlook for a person who's diagnosed with BRAF-mutated metastatic colon cancer today versus even 7 or 8 years ago. Dr. Kristen Ciombor: And we're seeing this over and over in other subtypes too, but how you choose to treat the patient up front really matters. So really giving the right regimen up front is the key here. Dr. Shaalan Beg: And along the same lines, Abstract 3501 wanted to answer the question on whether people with MSI-high metastatic colorectal cancer need double checkpoint inhibitor therapy or is single therapy enough. So this [CheckMate-8HW] study compared nivo plus ipi with nivo alone, nivo monotherapy for MSI-high metastatic colorectal cancer. And we've known that both of these are fairly active regimens, but we also know the chance of immune-related adverse events is significantly higher with combination therapy. So this was a much-needed study for this group of patients. And what were your takeaways here? Dr. Kristen Ciombor: This, of course, has been really nivo-ipi in the first-line MSI-high metastatic colorectal cancer is now a standard of care. And not everybody is eligible for it, and there could be reasons, toxicity reasons, and other things too. But as we've been seeing for the last couple of years, immunotherapy clearly beats chemo in this space. And now looking at doublet versus single immunotherapy treatment in the first line, I think really nivo-ipi does beat out monotherapy. I will say, however, there is a caveat in that we still haven't seen the nivo-ipi versus nivo in the first line. So what has been presented thus far has been across all lines of therapy, and that does muddy the waters a little bit. So definitely looking forward and and we've asked this many times and based on the statistical plan and and what not, you know, we just haven't seen that data yet. But I do think it's becoming increasingly important to consider doublet immunotherapy for these patients as long as there are no contraindications. With the again, with the caveat that we have to have these toxicity discussions in the clinic with patients because many patients can tolerate it, you know, this regimen fairly well, but there can be very severe toxicities. So, I think an informed discussion should really be had with each patient before moving forward. Dr. Shaalan Beg: Yeah, informed decision, making them aware of the potential of real significant toxicities, immune-related toxicities with double therapy. But I am curious in your practice, how often do you see people choosing doublet therapy as frontline? Dr. Kristen Ciombor: So patients are really savvy, and a lot of times they've heard this data before or have come across it in patient advocacy groups and other things, and it's really nice to be able to have that conversation of the risk versus benefit. So I will say not all of my patients choose doublet, and many of them are still cured with immunotherapy monotherapy. So the big question there is, will we ever understand who actually needs the doublet versus who can still be cured or have very good long-term outcomes with just the single agent? And that has not been answered yet. Dr. Shaalan Beg: What a great point. So the last abstract I was hoping we could talk about is POD1UM-303 or the INTERAACT2 subgroup analysis and impact of delayed retifanlimab treatment for patients with squamous cell carcinoma of the anal canal. What were your thoughts here? Dr. Kristen Ciombor: This was a study, actually we saw at ESMO, we saw the primary data at ESMO last year, and this was an update with some exploratory analyses. But this was really an important study because once again, we're looking at immunotherapy in later lines of therapy. That's how we started looking at and investigating immunotherapy, and now we're moving it up and up in the treatment course. So this was a study of carboplatin/paclitaxel plus or minus retifanlimab. Actually it was retifanlimab versus placebo. And it was a positive study, as we heard last year. This actually led to FDA approval of this regimen last month, just before ASCO, and it has now been incorporated in the NCCN guidelines as the preferred first-line option.  So what I thought was important from the additional data presented at ASCO was looking at the different subgroups, it did not appear that patients with liver mets or not had different outcomes. So that was really good to see because sometimes in colon cancer we see that immunotherapy doesn't work as well when patients have liver mets. And interestingly, because we use immunotherapy in anal cancer without any biomarkers, unlike with colon cancer or some of the other tumor types, also the authors looked at PD-L1 status, and it did look like maybe patients did a little bit better if they had higher PD-L1 expression, but patients still could benefit even if they were PD-L1 negative. So that was important, I think, and we will continue to see further data come out from this study. I want to mention also that EA2176 just completed accrual, so that was carbo-taxol plus or minus nivolumab. And so we should be seeing that data sometime soon, which will hopefully also confirm the ongoing role for immunotherapy in the first-line setting for anal cancer. Dr. Shaalan Beg: That was a fantastic review. Thank you, Dr Ciombor. Thanks for sharing your valuable insights with us today on the ASCO Daily News Podcast. Dr. Kristen Ciombor: Thanks for having me here. Dr. Shaalan Beg: And thank you to our listeners for your time today. You will find links to the abstracts discussed today in the transcript of this episode. And if you value the insights that you hear on the podcast, please take a moment to rate, review, and subscribe, wherever you get your podcasts. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. More on today's speakers:   Dr. Shaalan Beg  @ShaalanBeg  Dr. Kristen Ciombor @KristenCiombor Follow ASCO on social media:    @ASCO on Twitter   @ASCO on BlueSky  ASCO on Facebook    ASCO on LinkedIn    Disclosures:   Dr. Shaalan Beg:   Consulting or Advisory Role: Ipsen, Cancer Commons, Foundation Medicine, Science37, Nant Health, Lindus Health Speakers' Bureau: Sirtex Research Funding (Inst.): Delfi Diagnostics, Universal Diagnostics, Freenome Dr. Kristen Ciombor: Consulting or Advisory Role: Pfizer, Incyte, Exelixis, Bayer, ALX Oncology, Tempus, Agenus, Taiho Oncology, Merck, BeiGene Research Funding (Inst.): Pfizer, Boston Biomedical, MedImmune, Onyx, Bayer, Boehringer Ingelheim, Bristol-Myers Squibb, Merck, Novartis, Incyte, Amgen, Sanofi, Bristol-Myers Squibb, Array BioPharma, Incyte, Daiichi Sankyo, Nucana, Abbvie, Merck, Pfizer/Calthera, Genentech, Seagen, Syndax Travel, Accommodations, Expenses: Incyte, Tempus

Jared Wyllys, from CHGO, joins Jeremy & Pat this week. Tough week for the Cubs. We discuss the roster challenges at 3B, starting rotation, and the bullpen.  We look ahead to another tough stretch. We close the show with a profile of former Cub Luis Valbuena.  Enjoy....and Go Cubs!

987: Kelly Services is transforming the way enterprises approach staffing through AI-powered innovation, scalable tech, and smart acquisitions. In this episode of Technovation, Peter High speaks with Sean Perry, Chief Information Officer of Kelly Services, a $4.3B staffing and professional services company. Sean shares how he's driving modernization across IT, integrating recent acquisitions like Motion Recruitment, and developing innovative AI tools to deliver enterprise-wide value. From launching a custom AI assistant (GRACE) to implementing a modern tech stack across legacy systems, Sean reveals how Kelly is reshaping its digital future while improving candidate and client experiences. He also draws lessons from his time at Amazon and Robert Half to rethink internal products with a customer-first mindset.

The Nats lost on Friday night 6-5 at Dodger Stadium to open their nine game West Coast Road Trip. Mark (From LA) & Al discuss MacKenzie's Gore subpar's outing where he gave up five earned runs in over five innings of work. Gore issued four walks and only recorded four strikeouts, keeping him behind Boston Garrett Crochet for the MLB lead in strikeouts.(09:45) The offense slugged a trio of homers but was only 1 for 8 w/ RISP. Riley Adams ended an 0 for 32 slump in emphatic fashion with a solo HR in the top of the 5th to cut the deficit to 4-2.(18:00) Luis Garcia Jr. had a clutch pinch-hit 2-run double to trim the Dodger lead to 6-4 in the top of the 7th.  Amed Rosario got the nod at 2B (and homered) and Garcia replaced Andres Chapparo at DH for the pinch- hit opportunity.(21:10) Paul DeJong had four hits on Friday night in his rehab assignment with AA-Harrisburg. It is looking like DeJong will serve as an utility infielder for Washington as Brady House is now occupying 3B.(23:40) A quick look at what we know about the contractual situations for both the Manager and GM. 

Reading by Kara Cripps ---   1 Kings 10-11; 2 Chronicles 9   https://www.biblegateway.com/passage/?search=1%20Kings%2010-11%3B%202%20Chronicles%209&version=ESV&interface=print

Today's Headlines: Missile strikes between Israel and Iran have continued for six days, with President Trump escalating tensions online by demanding Iran's “unconditional surrender” and revealing the U.S. knows the ayatollah's location. Amid warnings from global powers and regional evacuations, Trump faces pushback at home, including a bipartisan congressional resolution requiring approval for U.S. involvement. Meanwhile in New York, Democratic mayoral candidate Brad Lander was arrested by ICE during a volunteer shift, prompting outrage, as Trump calls for more deportations in Democratic cities—despite his administration reversing course multiple times on where raids should occur. Elsewhere, Elon Musk's AI startup is reportedly seeking $4.3 billion in new funding after burning through its previous rounds, and Senate Republicans are proposing to sell 3.3 million acres of federal land in 11 Western states to raise revenue. Resources/Articles mentioned in this episode: CNN: June 17, 2025 – Israel-Iran conflict  Axios: Congress dodges preemptive confrontation with Trump over Iran  NYT: Brad Lander, NYC Mayoral Candidate, Arrested by ICE Agents at Immigration Courthouse Axios: Trump orders ICE to hit Democrat-run cities with deportation blitz  WaPo: Trump officials reverse guidance exempting farms, hotels from immigration raids  CBS News: DHS Secretary Kristi Noem brought to hospital due to allergic reaction  Bloomberg: Elon Musk's xAI in Talks to Raise $4.3B in Equity Funding WAPo: Senate GOP plan would sell millions of acres of Western public land Morning Announcements is produced by Sami Sage and edited by Grace Hernandez-Johnson Learn more about your ad choices. Visit megaphone.fm/adchoices

The Nats losing streak extended to nine games on Monday night as victory slipped through their fingertips in the 6-4 defeat. Mark & Al begin with Kyle Finnegan, who inherited a one run lead in the top of the 9th, but allowed a pair of Rockies homers, the only home runs he has given up this season.(09:00) Brady House went 0 for 3 with a walk in his MLB debut.  House was the #11 overall pick in the 2021 Draft and had a OPS of .872 this season thus far in AAA-Rochester. House looked comfortable defensively and Davey Martinez said pregame that House will be the everyday 3B.(14:40) Daylen Lile hit his first career MLB homer in the bottom of the 5th in his first game since returning from AAA. Lile swapped roster spots with Robert Hassell III after Sunday's defeat.(18:00) James Wood's 2-run HR in the bottom of the 5th put Washington ahead 4-3 until the fateful 9th inning. Wood is now up 18 homers on the season; which is tied for 5th most in the NL.(20:15) Riley Adams got the nod at catcher and is now 0 for his last 30 at the plate. His OPS is down to a paltry .325 and the catching situation continues to worsen for the franchise.(23:15) Jake Irvin gave up a 2-run HR in the top of the 1st and his opening frame ERA is a shocking 10.84; surprisingly more than his Mitchell Parker. Irvin ended his evening with six innings of work off of five hits.(27:15) A discussion on recent Washington Post stories covering the angst within the franchise during this brutal stretch.(36:30) A Nats Chat Flashback from July 19th, 2023 when Brady House was promoted to AA-Harrisburg after a brief stay at High-A Wilmington.