Podcasts about dapsone

"When we think of drug interactions, specifically, the National Cancer Institute actually defines this as a change in the way a drug acts in the body when taken with certain other drugs, herbals, or foods or when taken with certain medical conditions. Drug interactions may cause the drug to either be more or less effective or cause effects on the body that are not expected," Carissa Ganihong, PharmD, BCOP, oncology and bone marrow transplantation clinical pharmacist at Hackensack University Medical Center in New Jersey, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about interaction pathways. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0 Earn 0.5 contact hours of nursing continuing professional development (NCPD), including 30 minutes of pharmacotherapeutic content, by listening to the full recording and completing an evaluation at courses.ons.org by July 10, 2027. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report increased knowledge related to drug interactions in oncology care. Episode Notes  Complete this evaluation for free NCPD.  ONS Podcast™ episodes: Pharmacology 101 series ONS Voice articles: Are Your Patients Taking Herbs That May Interact With Their Cancer Drugs? Pharmacogenomics Testing Helps to Ensure That Effective Therapy Is Safe Therapy Use of Herbal Products Carries Risk for Drug Interactions, but Patient–Clinician Knowledge, Communication Remain Low What the Research Says About Drug Interactions and Medical Cannabis ONS books: Chemotherapy and Immunotherapy Guidelines and Recommendations for Practice (second edition) Clinical Guide to Antineoplastic Therapy: A Chemotherapy Handbook (fourth edition) ONS Huddle Cards: DPYD Gene and DPD Enzyme Pharmacogenomics ONS Oral Anticancer Medication Toolkit American Journal of Nursing articles: Understanding Pharmacokinetics: Part1: Drug Absorption Understanding Pharmacokinetics: Part 2: Drug Distribution Understanding Pharmacokinetics: Part 3: Drug Metabolism Understanding Pharmacokinetics: Part 4: Drug Elimination Journal of Nuclear Medicine Technology articles: Pharmacology, Part 1: Introduction to Pharmacology and Pharmacodynamics Pharmacology, Part 2: Introduction to Pharmacokinetics ClinPGx To discuss the information in this episode with other oncology nurses, visit the ONS Communities. To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "One of the most notable food interactions that interacts with many different medications is actually grapefruit or grapefruit juice. This is known to be a very strong CYP3A4 inhibitor. … A lot of medications are metabolized through the CYP3A4 pathway. By inhibiting the effect of these enzymes, that can actually increase and significantly increase the concentrations of these therapies. It's not an interaction that's just limited to grapefruit. I would say grapefruit being in the food interaction is kind of one of the most well-known, but it can also be seen with other foods as well, like pomegranate juice or a very specific type of orange called Seville oranges. And this is really just due to the presence of a substance called furanocoumarins." TS 6:12 "There have been a pretty large number of genes identified that are responsible for coding some of those common enzyme families that I had been discussing, some of those CYP450 enzymes, but other enzymes as well that are important for drug metabolism. Based on the type of gene, there could be some different categories where patients are normal metabolizers, intermediate metabolizers, or poor metabolizers. There are some other categories as well based on the type of gene we're looking at. And that can ultimately impact the way you are able to metabolize drugs." TS 15:56 "Another common [geneotypic variation] that we always think about in oncology is G6PD, where if someone has G6PD deficiency, these patients can be at greater risk of hemolytic anemias when receiving certain types of therapies. Dapsone and rasburicase are just a couple that have been associated with this risk." TS 17:50 "One of the big concerns is always polypharmacy. Our patients truly can be on a lot of medications. In the field that I work in, transplant, patients automatically from their transplant are on many, many different medications that can potentially predispose them to side effects. … But I think when it comes to the many drug interactions that may flag in these situations, we really have to look at the patient as a whole. Like, how long have these patients been on these therapies? Are they having side effects? Have they been on the combination for a very long time now? So I think that not just looking at the drug reference and seeing that there are like 10 different interactions flagged, but really assessing your patient as a whole can be very important—just because real-world practice, of course, is not black and white. It's often very gray, so it's just important to use clinical judgment in those scenarios." TS 26:10

Dr. Richard Horowitz returns for an in-depth discussion about the evolving science of Lyme disease, co-infections, and the MSIDS model—his groundbreaking 16-point system for diagnosing and treating chronic illness. From tick-borne infections to environmental toxins, neuroinflammation, and immune dysfunction, this conversation is a must-listen for anyone navigating the complexities of chronic Lyme disease. Ali Moresco shares her powerful personal healing journey using Dr. Horowitz's Dapsone Combination Therapy (DDS), illustrating how integrative protocols and identifying “terrain” issues like mold toxicity and MCAS made full recovery possible.

In this powerful episode of the Tick Boot Camp Podcast, we delve deep into the world of Lyme disease with Dr. Andi Campitelli, a highly experienced naturopathic doctor from Toronto, Canada. Dr. Campitelli shares her personal journey with Lyme disease, her unique 4-phase treatment approach, and invaluable insights for anyone struggling with chronic Lyme disease. Episode Highlights: Dr. Campitelli's Personal Lyme Story: Discover how a passion for preventative medicine, sparked by personal loss, led Dr. Campitelli to specialize in complex chronic illnesses like Lyme. The 4-Phase Lyme Treatment Framework: Learn about Dr. Campitelli's comprehensive approach, focusing on: Foundation: Addressing getting the body ready for treatment with things like gut health, detoxification, hormones, genetics, and inflammation. Natural Antimicrobials: Utilizing herbal/botanical tinctures, binders, etc. to address mold, SIBO, parasites, and infections (Lyme, Babesia, Bartonella, etc.). Judicious Use of Antibiotics and Pharmaceuticals: When and how a variety of antibiotics/pharmaceuticals can play a role in Lyme recovery, including Ivermectin, Hydroxychloroquine, Disulfiram, Dapsone, etc. Long-Term Maintenance: Strategies for sustained wellness and preventing relapse. Mental Health & Neuroplasticity: Explore the crucial role of mental health support and neuroplasticity in the Lyme recovery process. Detoxification Strategies: Understand the importance of supporting the body's natural detoxification pathways. Expert Insights from a Lyme-Literate Doctor: Benefit from Dr. Campitelli's experience treating over 1,000 Lyme patients and her own personal journey overcoming the disease. Connect with Tick Boot Camp: Listen to more inspiring stories and expert advice on our Tick Boot Camp Podcast. Subscribe on your favorite platform (Apple Podcasts, Spotify, YouTube Music) and join our community to liberate yourself and others from Lyme disease.

Introduction Welcome to a new episode of the Tick Boot Camp Podcast! In this insightful session, we're joined by Ethan Peterson and Josh Lindorf, who have significantly influenced the Lyme disease community. Their story gained attention after being featured on LymeDisease.org, sparking interest in their experiences and contributions to the community. Childhood Friendship and Lyme Disease Connection Ethan and Josh, childhood friends who reconnected in college, share their journey from early years to their struggle with Lyme disease. They discuss the potential link between their shared environment and the likelihood of contracting the disease, providing a unique perspective on community health and Lyme disease prevalence. Education and Outdoor Exposure in Utah Diving into their educational background, Ethan and Josh highlight how their upbringing in Utah, with its emphasis on outdoor activities, potentially increased their exposure to Lyme disease. They reflect on the lack of awareness and education regarding tick prevention and Lyme disease in their curriculum, underscoring the importance of incorporating these topics in health education. The Impact of Lyme Disease on Daily Life Our guests open up about the profound impact of Lyme disease on their lives. They recount their personal experiences with symptoms, misdiagnoses, and the transformative journey towards awareness and self-care. This section provides valuable insights into the often-overlooked aspects of living with Lyme disease. Navigating Diagnosis and Treatment Ethan and Josh share their diagnostic journeys, including the challenges they faced in obtaining accurate diagnoses and effective treatments. Their stories highlight the complexities of Lyme disease diagnosis and the importance of persistence and self-advocacy in the healthcare system. Treatments included Disulfiram, Dapsone, Ketamine, ozone, herbal antimicrobials, and oral and IV antibiotics. The Role of MyLymeData in Their Lives Discussing the significance of the MyLymeData project, our guests explain how it has been instrumental in their understanding and management of Lyme disease. They delve into the importance of data collection and community support in advancing Lyme disease research and awareness. Personal and Spiritual Growth Through Lyme Disease Exploring the intersection of faith and health, Ethan and Josh discuss how their experiences with Lyme disease have shaped their spiritual beliefs and personal growth. They emphasize the role of hope, resilience, and community support in their healing processes. Advocacy and Community Contribution Our guests reflect on their roles as advocates in the Lyme disease community. They share their motivations for helping others, the importance of spreading awareness, and their efforts in creating platforms for education and support. Conclusion: A Message of Hope and Resilience Ethan Peterson and Josh Lindorf's journey with Lyme disease is a testament to the power of resilience, awareness, and community support. Their story serves as an inspiration and a call to action for greater understanding and advocacy in the fight against Lyme disease. About the Tick Boot Camp Podcast The Tick Boot Camp Podcast, hosted by Matt Sabatello and Rich Johannesen, aims to empower individuals affected by Lyme disease and other tick-borne illnesses. Through sharing stories, building community, and fostering belief in healing, the podcast provides a platform for support and success modeling.

Dynamic speaker and long-time Lyme disease pioneer and ILADS co-founder Dr. Richard Horowitz talks about his Dapsone protocol and his new book on the climate emergency.  Have your notebook handy for this informational interview.

In this episode, Dr. Christopher Tookey and Dr. Rose Wolbrink discuss management of acne with a focus on over the counter creams, gels and ointments available at most stores and pharmacies.  A disclaimer, we're providing general guidance but everyone is different and you should always discuss with your health care professional management of any disease and therapy before trying anything you discover from a source on the internet (including this podcast). This podcast does not reflect the opinon of our employer. 

Interview with Dr. Randall Feuer, Texas Lyme specialist and Lyme patient Introduction to Dr Feuer and his personal Lyme story12 mins Congenital Lyme son14 his own dapsone protocol19 lack of treatment options for kids in TX22 Congenital Lyme and coinfections science and diagnosis24 OBGYN success and experience treating Lyme in pregnancy25 Preparing for testing baby ahead of delivery27 Treating patients28:30 holistic support34 detoxing and cytokines37 testing38:30 clinical dx and why testing is difficult to useparasites, heavy metals and mold58 LDI, low dose immunotherapy1 hour RESPECT for Lyme patients1:03 patient success104 disulfiram safely107 HOPE for patients108 Kristina's story and why she does interviews109 prepare for an apt113 THC/CBD  for neuro Lyme and getting off drug addictionSupport us by liking this video and subscribing to our channel.  Donate at www.TXLymeAlliance.org.  Thank you and prayers for full healing!Support the show

Bay Area Lyme Foundation Advisory Board Member, Richard Horowitz, MD, author of "Why Can't I Get Better?" speaks about his experience and novel research on Tick-borne Diseases, Fire/Smoke Exposure, Covid19, and Multiple Systemic Infectious Disease Syndrome (MSIDS)

In this episode you will learn three things: 1) How Disulfuram is being used to treat Lyme Disease. 2) Why Dr. Richard Horowitz is combining Dapsone and Disulfuram. 3) And How these treatments have lead to long term Lyme remission Dr. Horowitz, the best-selling author of “Why Can’t I Get Better? Solving the Mystery of Lyme and Chronic Disease,” has presented at numerous scientific conferences on Lyme Disease and the role of co-infections and toxins in Lyme Borreliosis. Dr. Leigner practices in Pawling, New York, and has been actively involved in diagnosis and treatment of Lyme disease and related disorders since 1988. His work has focused on the serious morbidity and (occasional) mortality that can comes from chronic and neurological Lyme Disease.

Author: Nick Hatch, M.D. Educational Pearls:   Methemoglobinemia is when the iron in hemoglobin is in the Fe3+ (ferric) state rather than the normal Fe2+  (ferrous) state. Methemoglobin cannot release oxygen at the tissues. Symptoms include cyanosis, headache, tachycardia, dyspnea, and lethargy. Suspect in setting of hypoxia that does not improve with oxygenation, and clinical cyanosis with a normal PaO2 on ABG. Treatment is methylene blue which reduces the iron back to the ferrous state. Causes can be Dapsone, Lidocaine, Benzocaine.   References: Agarwal N, Nagel RL, Prchal JT. Dyshemoglobinemias. In: Disorders of Hemoglobin: Genetics, Pathophysiology, and Clinical Management, 2nd ed, Steinberg M (Ed), 2009. P.607 Cortazzo JA, Lichtman AD. (2014). Methemoglobinemia: a review and recommendations for management. Journal of Cardiothoracic and Vascular Anesthesia. 28:1043. Darling R, Roughton F. (1942). The effect of methemoglobin on the equilibrium between oxygen and hemoglobin. American Journal of Physiology. 137:56.

People are suffering. From a feeling of hopelessness. From depression and anxiety. Add to that a despair that no one supports them, and you have a desperate individual at an increased risk of committing suicide. This topic hits close to home for Nadine, as she lost a nephew to suicide in 2007. Ian struggled with addiction issues, and he took his life at the age of 19. Because her family is predisposed to celiac disease, Nadine wonders if undiagnosed celiac disease may have been partially to blame for her nephew’s issues. Today she explores the mental health disorders that are associated with gluten getting through the blood-brain barrier. She also explains how undiagnosed celiac disease puts patients at an increased risk for morbidity, and stresses the fact that celiac disease can—and will—kill you if it goes untreated. Listen in as the Gluten Free RN tells her own story of improved mental health on a gluten-free diet. She also covers the types of cancers that might be prevented by going gluten-free, the connection between AFib and celiac disease, and how dermatitis herpetiformis affects patients. Listen and learn the best diet to help you get better, faster, and why medical professionals need to pay more attention to the intestines! What’s Discussed:  How to define morbidity and mortality Morbidity = sickness Mortality = death People with undiagnosed celiac disease have increased risk for morbidity How morbidity presents itself in undiagnosed celiac patients Chronic anemia Fatigue Osteoporosis Failure to thrive, grow Infertility Thyroid issues Autoimmune disorders Type 1 diabetes Lupus MS Sjögren’s Information from the World Health Organization (WHO) Diarrheal diseases are #1 killer of children Only funded one celiac study 1:19 rate in pediatric patients of Sahrawi descent The prominent mental health issues associated with celiac disease Depression Anxiety Anti-social behavior Suicide How removing gluten from her diet improved Nadine’s mental health Brain fog went away ‘Got brain back’ Embrace all life has to offer Freeing to know cause of symptoms The grains that contain gluten Wheat Barley Rye Oats (cross-contamination) The Paleo diet Nadine suggests for celiac and gluten-sensitive patients Whole food Focus on local, fresh 100% grass-fed meat (no antibiotic, no hormone) Fish and eggs Nuts and seeds 100% organic fruits and vegetables Nadine’s experience with celiac disease Multi-system organ failure, seven auto-immune disorders Dermatitis herpetiformis Diagnosed by dermatologist Tests negative, but HLA-DQ2.5 gene carrier (both parents) The connection between AFib and celiac disease AFib puts patient at risk for stroke, sudden death Check for magnesium RBC deficiency Can be corrected with gluten-free diet Resolve without pharmaceuticals How dermatitis herpetiformis affects patients Extremely painful, itchy skin Manifestation of celiac disease Suicide rate higher in patients with DH Dapsone alone will not heal Must also go gluten-free Prolonged use of Dapsone is toxic to liver (bowel cancer, lymphoma) The cancers that are potentially preventable on a gluten-free diet Lymphoma Small intestinal adenocarcinoma Esophageal cancer Oral pharyngeal The genes that indicate a predisposition to celiac disease HLA-DQ2 HLA-DQ8 Other disorders that could be mitigated by a gluten-free diet Chronic anemia Osteoporosis Osteomalacia Thyroid disorder Dementia Alzheimer’s MS Type 1 diabetes How long it takes to receive celiac diagnosis in US 9-15 years The risks for patients diagnosed with celiac disease in childhood Threefold increased risk of death (suicide, accidental death, violence) Nadine’s research around celiac testing in autopsy Couldn’t get straight answer from medical examiner (state of Oregon) Study conducted in 1974 concluded that despite systematically positive response to gluten-free diet, some patients ended up with lymphoma How Nadine periodically gives her system a detox Limited fast (three to seven days) Give organs, immune system a rest Why medical professionals should give more attention to the intestines Vast majority of signs, symptoms originate in intestines 70-90% of immune system in intestines Homocysteine levels higher in newly diagnosed celiac patients, related to other health issues The issues that can result from undiagnosed celiac disease Heart attack Stroke Appendix removed Gall bladder removed The definition of refractory celiac disease Intestines don’t heal even on gluten-free diet Sometimes caused by continued exposure to trace amounts of gluten Some patients past point of being able to heal Why it’s crucial to remove all gluten from the environment Celiac patients should feel safe where live, work and go to school Even trace amounts cause continued symptoms, early death Takes an emotional toll to be hypervigilant, mocked by loved ones The connection between undiagnosed celiac disease the despair that leads to suicide No hope of getting better Don’t feel supported, believed (celiac is real disease) Depression, anxiety and other mental health disorders More vulnerable if undiagnosed and enduring abusive relationship What happens when gluten gets through a leaky blood-brain barrier Inflammation of the brain Hypoxia (decreased oxygen flow) Low end—brain fog, anxiety, depression, fatigue High end—bipolar disease, antisocial behavior, learning disabilities, schizophrenia The risks associated with eating traditionally grown fruits and vegetables Glyphosate in Roundup causes leaky gut The goals of the first six months on a gluten-free diet Remove all gluten Allow villi to grow back Heal inflammation Repair immune system Resources:   Celiac Disease and Gluten Sensitivity in Down, Turner and Williams Syndrome WHO Celiac Disease Study “Necropsy Studies on Adult Coeliac Disease” in the Journal of Clinical Pathology “Mortality in Celiac Disease” in Gastroenterology “The Global Burden of Celiac Disease” in PLoSONE “The Unknown Burden and Cost of Celiac Disease in the US”  in Expert Review of Pharmacoeconomics and Outcomes Research “Long-Term Mortality in People with Celiac Disease Diagnosed in Childhood Compared with Adulthood” in the American Journal of Gastroenterology “Increased Risk of Atrial Fibrillation in Patients with Coeliac Disease: A Nationwide Cohort Study” in the European Heart Journal “Increased Suicide Risk in Coeliac Disease—A Swedish Nationwide Cohort Study” in Digestive and Liver Disease “The Burden of Celiac Disease and the Value of Having It Diagnosed” by Fredrik Norström of UMEA University “Complications of Coeliac Disease: Are All Patients at Risk?” “Evidence-Informed Expert Recommendations for the Management of Celiac Disease in Children” in Pediatrics Connect with Nadine:  Instagram Facebook Contact via Email ‘Your Skin on Gluten’ on YouTube Melodies of the Danube Gluten-Free Cruise with Nadine Books by Nadine: Dough Nation: A Nurse's Memoir of Celiac Disease from Missed Diagnosis to Food and Health Activism

Why You Should Listen: In this episode, you will learn about Lyme Disease, co-infections, persister cell regimens, and the MSIDS model of chronic illness. About My Guest: My guest for this episode is Dr. Richard Horowitz, MD. Dr Richard Horowitz is a board certified internist in private practice in Hyde Park, N.Y. He is medical director of the Hudson Valley Healing Arts Center, an integrative medical center which combines both classical and complementary approaches in the treatment of Lyme Disease and other tick-borne disorders. He has treated over 12,000 Chronic Lyme disease patients in the last 26 years, with patients coming from all over the US, Canada, and Europe to his clinic. He is one of the founding members and past president elect of ILADS, the International Lyme and Associated Diseases Society. He is also past president of the ILADEF, the International Lyme and Associated Diseases Educational Foundation, a non-profit organization dedicated to the education of health care professionals on tick-borne diseases. Dr Horowitz has presented at numerous local, national, and international scientific conferences on Lyme Disease, and has published on the role of co-infections and toxins in Lyme Borreliosis. He was awarded the Humanitarian of the Year award by the Turn the Corner Foundation for his treatment of Lyme Disease, and has dedicated his life to helping those stricken with this devastating illness. He has written two bestselling books on Lyme disease. The first “Why Can't I Get Better? Solving the Mystery of Lyme and Chronic Disease” in 2013 and his most recent “How Can I Get Better?: An Action Plan for Treating Resistant Lyme & Chronic Disease” which just came out in February of 2017. Both of these are top resources for those that want to understand Lyme disease and all the things that come with it. Key Takeaways: - What is MSIDS and why do we need to look beyond Lyme? - How is Lyme disease transmitted? - How is treatment of coinfections approached? - What is Dapsone and what is a persister cell? - Is mold a common issue in chronic Lyme patients? - How common are parasites and is treating them important? - How does one approach detoxification? - What is the role of chronic viruses? - Do EMFs matter? - What is the impact of Mast Cell Activation Syndrome (MCAS)? - Does the mental/emotional backdrop contribute to chronic illness? - What is Lyme here to teach us? Connect With My Guest: http://www.cangetbetter.com Related Resources: Why Can't I Get Better: http://betterhealthguy.link/WhyCantIGetBetter How Can I Get Better: http://betterhealthguy.link/HowCanIGetBetter Interview Date: April 15, 2017 Disclaimer: The content of this show is for informational purposes only and is not intended to diagnose, treat, or cure any illness or medical condition. Nothing in today's discussion is meant to serve as medical advice or as information to facilitate self-treatment. As always, please discuss any potential health-related decisions with your own personal medical authority.

On this episode of the ‘Gluten Free RN,’ Nadine explains how gluten affects your skin. If you have celiac disease or a gluten intolerance, you may also suffer from dermatitis herpetiformis, a painful rash that is often misdiagnosed. Nadine shares her struggle with DH and offers advice about eliminating gluten from both your diet and personal care regime in order to heal your skin. The only treatment for this issue is a 100% gluten-free diet. Your skin is the largest organ in your body, so listen and learn how to keep it looking and feeling good! What’s Discussed:  The definition of Dermatitis Herpetiformis (DH) Blistering, vesicular rash that is typically round Itchy, very painful and distracting Caused by IgA deposits under the skin May appear on hands, legs, back, armpits, buttocks, elbows, knees, scalp, torso and even eyes Not contagious The only treatment is a 100% gluten-free diet  Nadine’s struggle with DH Blisters, itchy and painful hands as a child Irritated by latex gloves as a nurse, hands developed rash Misdiagnosed by several dermatologists DH finally identified by Dr. Abigail Haberman Rash had exploded all over Nadine’s body and she was near death Most of the rash resolved quickly after adopting a gluten-free diet  Why steroid creams, long-term antibiotics and dapsone aren’t the answer DH is an external expression of what’s happening internally Topical creams don’t treat the underlying cause Long-term antibiotics disrupt the microbiome and put you at risk for developing other infections Dapsone is associated with serious side effects for the blood and liver Removing gluten from your diet and personal care products is the only cure  The importance of eliminating gluten from personal care products Anything you put on your skin can travel through to your bloodstream Discontinue the use of products that contain wheat, barley, rye or oats Nadine also recommends eliminating products that contain chemicals such as lauryl sulfates and paraffins  Resources Mentioned:  YouTube: Your Skin on Gluten Primal Pit Paste ZuZu Luxe Cosmetics Red Apple Lipstick Desert Essence Organics Gluten-Free Danube Cruise Connect with Nadine:  Instagram Facebook Contact via Email Books by Nadine: Dough Nation: A Nurse's Memoir of Celiac Disease from Missed Diagnosis to Food and Health Activism

Your Guide to Ending Acne

Your Guide to Ending Acne