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Can a single infection permanently change your health, or does it simply reveal something that was already there? In this episode, host Dr. Linda Bluestein, the Hypermobility MD, welcomes back Dr. Ina Stephens, Associate Director of the UVA Health EDS & Hypermobility Disorders Center, for an in-depth discussion about Long COVID, post-infectious syndromes, and their connection to Ehlers-Danlos syndromes (EDS), hypermobility spectrum disorders (HSD), and immune dysfunction. Dr. Stephens explains why post-infectious illnesses are real and have been recognized for more than a century, tracing the pattern from the 1917 influenza pandemic and encephalitis lethargica to modern conditions including Long COVID, reactivated Epstein-Barr virus (EBV), Lyme disease, Babesia and other tick-borne infections, and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). She shares the detective work behind her Diagnostic Dilemma Clinic, how a comprehensive history and targeted evaluation uncover hidden diagnoses, and why so many patients with complex chronic illness also have hypermobility. The conversation explores emerging research showing that people with hypermobility are approximately four times more likely to develop Long COVID, with an even greater risk in those with postural orthostatic tachycardia syndrome (POTS) and mast cell activation syndrome (MCAS). Dr. Stephens and Dr. Bluestein discuss the underlying biology, including immune dysregulation, autonomic nervous system dysfunction, vagus nerve dysfunction, mitochondrial dysfunction, and the ways connective tissue disorders may influence recovery after infection. They also review evidence-informed treatment strategies, including supporting mitochondrial health with coenzyme Q10 (CoQ10), glutathione, and N-acetylcysteine (NAC); the role of low-dose naltrexone (LDN); optimizing iron and vitamin C status; when antiviral medications may be appropriate; intravenous immunoglobulin (IVIG); and glucagon-like peptide-1 (GLP-1) receptor agonists. Finally, they explain why gradually increasing muscle mass and strength may have a greater long-term impact than any single supplement and share practical strategies for supporting recovery and strengthening your regimen at the first sign of illness. Whether you're living with EDS, HSD, Long COVID, POTS, MCAS, ME/CFS, Lyme disease, or another post-infectious condition, this episode offers practical, science-based insights into why these conditions overlap and what you can do to support healing. Takeaways: • Can a virus, Lyme disease, or another infection permanently change your health? Learn why post-infectious syndromes have been documented for more than a century and how infections can trigger chronic illness through immune dysregulation and autoimmunity. • Why are people with Ehlers-Danlos syndromes (EDS) and hypermobility spectrum disorders (HSD) so much more likely to develop Long COVID? Discover the research linking hypermobility, POTS, mast cell activation syndrome (MCAS), and prolonged recovery after infection. • What do Long COVID, Lyme disease, ME/CFS, POTS, and other post-infectious conditions have in common? Explore the shared biology of immune dysfunction, autonomic and vagus nerve dysfunction, and mitochondrial dysfunction that may explain multisystem symptoms. • Which treatments actually help? Hear the evidence behind coenzyme Q10 (CoQ10), glutathione, N-acetylcysteine (NAC), low-dose naltrexone (LDN), iron and vitamin C, antiviral medications, intravenous immunoglobulin (IVIG), and glucagon-like peptide-1 (GLP-1) receptor agonists. • Could building muscle be one of the most powerful treatments for chronic illness? Learn why increasing muscle mass and strength may have a greater long-term impact than any single supplement, plus Dr. Stephens' practical strategy for boosting your regimen at the first sign of infection. Go http://www.AquaTru.com now for 20% off (your purifier) using promo code BENDY. Want to learn more about the UVA EDS Center? For Appointments and Questions: RUVAEDSCenter@uvahealth.org UVA EDS: https://www.uvahealth.com/healthy-practice/advancing-care-through-ehlers-danlos-clinic UVA EDS FAQ: https://www.uvahealth.com/support/eds/faq UVA Pediatric Integrative Medicine: https://childrens.uvahealth.com/specialties/integrative-health Want more Dr. Linda Bluestein, MD? Website: https://www.hypermobilitymd.com/ YouTube: https://www.youtube.com/@bendybodiespodcast Instagram: ⁠⁠⁠⁠https://www.instagram.com/hypermobilitymd/⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠https://www.facebook.com/BendyBodiesPodcast⁠⁠⁠⁠ X: ⁠⁠⁠⁠https://twitter.com/BluesteinLinda⁠⁠⁠⁠ LinkedIn: ⁠⁠⁠⁠https://www.linkedin.com/in/hypermobilitymd/⁠⁠⁠⁠ Newsletter: ⁠⁠⁠⁠https://hypermobilitymd.substack.com/ Shop my Amazon store ⁠⁠⁠ https://www.amazon.com/shop/hypermobilitymd Dr. Bluestein's Recommended Herbs, Supplements and Care Necessities: https://us.fullscript.com/welcome/hypermobilitymd/store-start Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them. Join YOUR Bendy Bodies community at ⁠⁠https://www.bendybodiespodcast.com/⁠⁠. YOUR bendy body is our highest priority!⁠⁠ Learn more about Human Content at ⁠⁠⁠http://www.human-content.com⁠⁠⁠ Podcast Advertising/Business Inquiries: ⁠⁠⁠sales@human-content.com⁠⁠⁠ Part of the Human Content Podcast Network FTC: This video is not sponsored. Links are commissionable, meaning I may earn commission from purchases made through links Learn more about your ad choices. Visit megaphone.fm/adchoices

Can a single infection permanently change your health, or does it simply reveal something that was already there? In this episode, host Dr. Linda Bluestein, the Hypermobility MD, welcomes back Dr. Ina Stephens, Associate Director of the UVA Health EDS & Hypermobility Disorders Center, for an in-depth discussion about Long COVID, post-infectious syndromes, and their connection to Ehlers-Danlos syndromes (EDS), hypermobility spectrum disorders (HSD), and immune dysfunction. Dr. Stephens explains why post-infectious illnesses are real and have been recognized for more than a century, tracing the pattern from the 1917 influenza pandemic and encephalitis lethargica to modern conditions including Long COVID, reactivated Epstein-Barr virus (EBV), Lyme disease, Babesia and other tick-borne infections, and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). She shares the detective work behind her Diagnostic Dilemma Clinic, how a comprehensive history and targeted evaluation uncover hidden diagnoses, and why so many patients with complex chronic illness also have hypermobility. The conversation explores emerging research showing that people with hypermobility are approximately four times more likely to develop Long COVID, with an even greater risk in those with postural orthostatic tachycardia syndrome (POTS) and mast cell activation syndrome (MCAS). Dr. Stephens and Dr. Bluestein discuss the underlying biology, including immune dysregulation, autonomic nervous system dysfunction, vagus nerve dysfunction, mitochondrial dysfunction, and the ways connective tissue disorders may influence recovery after infection. They also review evidence-informed treatment strategies, including supporting mitochondrial health with coenzyme Q10 (CoQ10), glutathione, and N-acetylcysteine (NAC); the role of low-dose naltrexone (LDN); optimizing iron and vitamin C status; when antiviral medications may be appropriate; intravenous immunoglobulin (IVIG); and glucagon-like peptide-1 (GLP-1) receptor agonists. Finally, they explain why gradually increasing muscle mass and strength may have a greater long-term impact than any single supplement and share practical strategies for supporting recovery and strengthening your regimen at the first sign of illness. Whether you're living with EDS, HSD, Long COVID, POTS, MCAS, ME/CFS, Lyme disease, or another post-infectious condition, this episode offers practical, science-based insights into why these conditions overlap and what you can do to support healing. Takeaways: • Can a virus, Lyme disease, or another infection permanently change your health? Learn why post-infectious syndromes have been documented for more than a century and how infections can trigger chronic illness through immune dysregulation and autoimmunity. • Why are people with Ehlers-Danlos syndromes (EDS) and hypermobility spectrum disorders (HSD) so much more likely to develop Long COVID? Discover the research linking hypermobility, POTS, mast cell activation syndrome (MCAS), and prolonged recovery after infection. • What do Long COVID, Lyme disease, ME/CFS, POTS, and other post-infectious conditions have in common? Explore the shared biology of immune dysfunction, autonomic and vagus nerve dysfunction, and mitochondrial dysfunction that may explain multisystem symptoms. • Which treatments actually help? Hear the evidence behind coenzyme Q10 (CoQ10), glutathione, N-acetylcysteine (NAC), low-dose naltrexone (LDN), iron and vitamin C, antiviral medications, intravenous immunoglobulin (IVIG), and glucagon-like peptide-1 (GLP-1) receptor agonists. • Could building muscle be one of the most powerful treatments for chronic illness? Learn why increasing muscle mass and strength may have a greater long-term impact than any single supplement, plus Dr. Stephens' practical strategy for boosting your regimen at the first sign of infection. Go http://www.AquaTru.com now for 20% off (your purifier) using promo code BENDY. Want to learn more about the UVA EDS Center? For Appointments and Questions: RUVAEDSCenter@uvahealth.org UVA EDS: https://www.uvahealth.com/healthy-practice/advancing-care-through-ehlers-danlos-clinic UVA EDS FAQ: https://www.uvahealth.com/support/eds/faq UVA Pediatric Integrative Medicine: https://childrens.uvahealth.com/specialties/integrative-health Want more Dr. Linda Bluestein, MD? Website: https://www.hypermobilitymd.com/ YouTube: https://www.youtube.com/@bendybodiespodcast Instagram: ⁠⁠⁠⁠https://www.instagram.com/hypermobilitymd/⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠https://www.facebook.com/BendyBodiesPodcast⁠⁠⁠⁠ X: ⁠⁠⁠⁠https://twitter.com/BluesteinLinda⁠⁠⁠⁠ LinkedIn: ⁠⁠⁠⁠https://www.linkedin.com/in/hypermobilitymd/⁠⁠⁠⁠ Newsletter: ⁠⁠⁠⁠https://hypermobilitymd.substack.com/ Shop my Amazon store ⁠⁠⁠ https://www.amazon.com/shop/hypermobilitymd Dr. Bluestein's Recommended Herbs, Supplements and Care Necessities: https://us.fullscript.com/welcome/hypermobilitymd/store-start Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them. Join YOUR Bendy Bodies community at ⁠⁠https://www.bendybodiespodcast.com/⁠⁠. YOUR bendy body is our highest priority!⁠⁠ Learn more about Human Content at ⁠⁠⁠http://www.human-content.com⁠⁠⁠ Podcast Advertising/Business Inquiries: ⁠⁠⁠sales@human-content.com⁠⁠⁠ Part of the Human Content Podcast Network FTC: This video is not sponsored. Links are commissionable, meaning I may earn commission from purchases made through links Learn more about your ad choices. Visit megaphone.fm/adchoices

Nutrition After Stroke: Eating Safely When Swallowing Is Hard | Stronger After Stroke After a stroke, something as simple as eating can suddenly feel overwhelming or even dangerous. If you or someone you love has been told they need a modified texture diet, you probably have more questions than answers. In this episode of "Stronger After Stroke," Rosa Hart, BSN, R.N., SCRN, stroke nurse navigator, Norton Neuroscience Institute, sits down with Bethany Farmer, RDN, LDN, M.Ed., registered dietitian and clinical nutritionist, to take the confusion out of eating safely at home after stroke. Bethany brings clinical expertise and practical real-world guidance to the table. She breaks down what a modified texture diet means, how the IDDSI (International Dysphagia Diet Standardisation Initiative) framework works, and why following the prescribed diet level is one of the most important things a stroke survivor can do to protect their recovery. In this episode, you'll hear about: ·      What modified texture diets are and why they matter after stroke ·      Common foods that seem safe but can be dangerous for people with swallowing difficulties ·      How to thicken liquids correctly and consistently at home ·      Practical tips for keeping meals nutritious, appealing and dignified ·      Signs that swallowing may be improving and when to ask for a reevaluation ·      How caregivers can support safe mealtimes without added stress One of the biggest fears involving dysphagia is that mealtimes will never feel normal again. Bethany's message is one of both caution and hope. With the right knowledge and the right team, eating can still be safe, satisfying and even enjoyable. Whether you are a stroke survivor navigating a new way of eating, a caregiver trying to keep your loved one safe at the table or a clinician looking for patient-friendly resources to share, this episode is packed with information you can use right away. Want more inspiring stories and real-life resources? Subscribe and share "Stronger After Stroke" with someone who needs a little extra support navigating life after stroke. For more support after stroke, check out the programs available virtually and in person through Norton Neuroscience Institute Resource Centers: https://nortonhealthcare.com/services-and-conditions/neurosciences/patient-resources/resource-center/ If you enjoyed this podcast, listen to Norton Healthcare's "MedChat" podcast, available in your favorite podcast app. "MedChat" provides continuing medical education on the go and is targeted toward physicians and clinicians. Norton Healthcare, a not-for-profit healthcare system, is a leader in serving adult and pediatric patients throughout Greater Louisville, Southern Indiana, the commonwealth of Kentucky and beyond. A strong research program provides access to clinical trials in a multitude of areas. More information about Norton Healthcare is available at NortonHealthcare.com.   Date of original release: July 13, 2026

Confidently counsel on nutrition, as we discuss different dietary patterns and address common patient queries. We are joined by Dr. Joan Salge Blake (Boston University).Claim CME for this episode at curbsiders.vcuhealth.org!Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CMEShow Segments Intro Case Ketogenic Diets Mediterranean & DASH Diets Fiber Oils and Fats Processed Foods Paleolithic and Carnivore Diets Food Order and Glycemic Control Protein Vegetarian and Vegan Diets Intermittent Fasting and Meal Timing Artificial Sweeteners Outro Credits Producer, Writer, Show Notes, Infographic, and Cover Art: Edison Jyang, MD Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP    Reviewer: Leah Witt, MD Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Technical Production: PodPaste Guest: Joan Salge Blake, EdD, MS, RDN, LDN, FAND DisclosuresJoan Salge Blake, EdD, MS, RDN, LDN, FAND  reports no relevant financial disclosures. The Curbsiders report no relevant financial disclosures. Sponsor: FIGSCurbsiders listeners can get 15% off. Just go to WearFIGS.com and use code FIGSRX. Sponsor: UpToDate For a limited time, get 10% off UpToDate packages with code CURB10. Visit https://store.uptodate.com/ to save on your annual or longer personal UpToDate subscription today. Sponsor: Continuing Education CompanyVisit CMEmeeting.org/curbsiders and use promo code Curb30 for 30% off all webcasts and THANKYOU40 for up to 40% off online courses  The customer appreciation 40% off offer ends on June 30th.

Dr. Deb Muth 00:02What if I told you that before a single drop of chemotherapy goes into a cancer patient’s body, we can take a blood sample, grow their actual living cancer cells in a lab, and test 70 different drugs against those cells, all outside the patient’s body, to find out which ones actually work. And what if I told you that the conventional oncology doesn’t routinely use this test? Well, today we’re going to talk about why that matters and we’re going to go through and I’m going to share a story that is very personal to me. It’s about a 38 year old man with a rare complex cancer diagnosis and the precision testing that is helping to keep that cancer from progressing. Stay with me. This is one that is going to change how you think about cancer treatment. Dr. Deb Muth 01:05You guys can put a little ad right in here before we start the next segment here. Hey everybody, welcome back to Let’s Talk Wellness Now. I’m Dr. Deb and today we’re going deep. I mean really deep. It’s some of the most cutting edge cancer testing I have ever seen in clinical practice. Now, normally I don’t talk about cancer. And I would not be sharing this story if it was anyone other than my own family. I do have permission to share and talk about this publicly. So I want to do this. I want to make sure that I share this message. And he is giving his blessing to share this story because we both believe that it can save lives. So his name is Cameron. He’s 38 years old. And he is my son-in-law. And two years ago, he came to me with a small lymph node underneath his arm and a bullseye rash. So of course, being the lime literate person that I am, my first inclination was to say, yeah, this makes sense. You have an enlarged lymph node because you have this bullseye rash. You got bit by the tick. Let’s keep an eye on it. If it doesn’t go away, let me know. So Fast forward a year and a half later, he comes to me and says, mom, what do you think about this? This thing is getting a little bit larger. And I said, yeah, it’s a little larger. Not sure. Let’s keep an eye on it. He wasn’t feeling anything. All his labs looked okay. And then one day he was out chopping wood and he started getting numbness in that arm and he felt it again. And it had exploded in size. And so after some evaluation with my daughter and him, we decided to do a ultrasound. And we thought what was going to come back was a fatty tumor. It felt like one looks like one responded to one. He’s 38 years old. He’s healthy. There’s nothing in our mind that’s ever thinking the result that we’re going to get back. Dr. Deb Muth 03:28Is a possible lymphoma. Needless to say, we were shocked by that ultrasound result. And we go fast forward, we have the biopsy. I requested a total excisional biopsy. I was told by the oncologist that that was old school. They don’t do that that way anymore. And I need to stay out of this. I need to let the experts take care of this because that’s what they do best. And this came from a breast surgeon here in Wisconsin. And so I stepped back for a moment. I let him do his biopsy and what came back was adenocarcinoma of an unknown origin. Had we excised the entire lymph node, we would have had more tissue to work with. I think we could have gotten a better diagnosis. So over the course of the next two and a half, three months, we have some more imaging done. We have some more testing done. They send a pathology out to Mayo Clinic. And what continues to come back is this incongruent test results. If anybody’s ever had this, it’s extremely frustrating. One test shows lymphoma. Now it shows breast cancer. Then the next week it shows estrogen receptor HER2 positive breast cancer. Two weeks later, another test comes back and it says, no, it’s not HER2, it’s triple negative breast cancer. And now it looks like it’s out of the lymph nodes. Now it looks like it’s in the lymph nodes. And we do a PET scan and they can’t find cancer anywhere except in this axilla area. But now we find a lymph node on the right side. So it must have spread.Let’s go ahead and do a biopsy on that. And so they biopsy the right side and the right side comes back with nothing other than tattoo ink. Now, all of this is kind of crazy. I am not a cancer specialist. I want to start by saying that I am not a cancer specialist. What I am sharing today is from a mother-in-law’s perspective, from a medical detective’s perspective, I do know how to do research. I do know how to find answers. And so what I’m going to share with you Dr. Deb Muth 05:54Is totally my opinion and totally my experience. And I’m not telling anybody to do anything different than what their doctors are telling them to do. But I am telling you to ask questions. So I go deep down the rabbit hole and find out that Tattoo Ink can appear like metastatic cancer on a PET scan. And we all know everybody gets tattoos today. They’re all over everyone. And yet we’re not thinking about how this tattoo ink can cause problems for us down the road, not to mention that there are heavy metals in them and it’s a toxin and it’s creating an inflammatory process in your body that your body’s constantly trying to get rid of. So the surgeon says to us, well, yes, that’s normal that that lymph nodes inflamed. It’s normal that there’s tattoo ink in it. The body’s doing what it’s supposed to do. It’s trying to get rid of a toxin. Okay. I will agree with that, but My son-in-law is covered with tattoos everywhere. And why didn’t we mention the tattoo ink that was found in the left axilla? We are only mentioning it in the right axilla. So there’s a lot of controversy, a lot of confusion. Many of you would never know any of this because A, you either don’t look at your lab results. And if you do, you don’t understand what you’re looking at. And that creates a problem for us, right? You don’t know what questions to ask. So we go into the doctor and the doctor tells us you have cancer and we’re going to swoop you in. And in the next two weeks, you’re going to be doing chemotherapy and radiation. And six months from now, we’re going to be doing surgery and there’s no time for questions and you’re scared shitless and you’re just doing what you can to survive. And I get that. And I totally understand that. And I appreciate that. But I’m telling you that If that is your choice, that is your choice. But as you’re doing that, take the time to ask the right questions. When this happened to us, there was a lot of challenging things with the oncology team. Nobody bothered to allow them to be a partner in their care. They dictated their care, but didn’t allow them to be a partner. So, Dr. Deb Muth 08:17Here’s what most oncologists do when patients get a cancer diagnosis. They look at the tumor type, they look at the stage, they look up the NCC guidelines, the National Comprehensive Cancer Network, and they follow the algorithm. Now, I have an enormous respect for conventional oncology. I really do. Working with cancer is probably one of the hardest things in medicine that anyone can do. The advances in this field over the last 10 years have been remarkable. But here’s my issue. Standard treatment assumes your cancer is the same as the cancer in the clinical trial that created the guidelines. It’s assuming that you and your cancer are the exact same as everyone else. You are the unique fingerprint, not the cancer. And this is the problem because your cancer is unique, just as unique as if you had your fingerprint taken, the mutations driving your tumor, the drugs your cancer cells are sensitive to, the metabolic vulnerabilities of your cancer. These are all different from the person sitting next to you in the chemo suite that has the same triple negative breast cancer or HER2 positive breast cancer or prostate cancer or colon cancer that you have. So what do do about that? Well, in my world, in the integrative medicine world, we test precisely, intelligently with the tools that most oncologists have never heard of. Or if they have, they haven’t incorporated it into their treatment modality for a variety of reasons. Either it’s not acceptable by the organization that they work for, they don’t understand it, They’re not going to be able to change their protocol anyway because they have to follow the NCCN protocol. So they don’t do it or they use a portion of it and they don’t do anything outside the protocol. So today I want to cover three things with you, three tools that we used that I think every cancer patient should be asking for when they start treatment or wherever you are in treatment at this point. Dr. Deb Muth 10:44you need to have these tests done. I don’t have any affiliation with any of these companies. I don’t get paid to tell you any of this. So let me just start by saying that I understand the chemistry behind these and how important it is to give you precision cancer treatment. And that’s why I’m talking about them today. The first one we’re going to talk about is the North Star response. This is your cancer surveillance score in the blood. How much cancer is circulating in the blood. The North Star Select, your cancer’s genomic blueprint from a blood draw. And the Datar Cancer Genetic Chemoscale, the live cell drug sensitivity test that tells us which drugs actually kill your cancer. So let’s go. Let’s dive into this. Let me just take a drink here. I’m going to cough a little bit. I apologize. I have this horrible tickle. It just never seems to go away, but that is not for today to discuss. So what is all of this? OK, the North Star response is a test that was developed by a company called Billion to One. And yes, that name is intentional because of the precision involved. It’s a next generation sequencing test, meaning it reads DNA at an incredibly detailed level. And it looks at something called methylated circulating tumor DNA or methylated CT DNA. Now let me break this down in plain English for you, because this can get a little overwhelming. When the cancer cells die or shed, they release tiny fragments of DNA into your bloodstream. We call this cell-free DNA or CFDNA, and it’s hidden within that cell-free DNA. And there are fragments that come from tumor cells. We call those CT DNA or circulating tumor DNA. Here’s what makes North Star’s response different. Rather than just looking for mutations in that tumor DNA, which is what most liquid biopsies do, and a liquid biopsy is just a blood test, Dr. Deb Muth 13:03This test looks at something called methylation patterns. Think of methylation like a dimmer switch on a gene. In healthy cells, certain genes are switched on and off in a very predictable way. In cancer cells, those dimmer switches go haywire. And cancer DNA has a characteristic hypermethylation, meaning switches are turning on and should be off or off and they should be on. And these patterns are essentially a cancer fingerprint in the blood. Now the North Star response scans more than 2000 locations in the genome for these cancer specific methylation patterns. And then it adds them all up into a single number called the tumor methylation score or TMS. So for Cameron, Cameron’s blood which was drawn on April 20th, 2026, his baseline tumor methylation score came back at 13. Now here’s the critical thing, to understand this was his baseline test, his starting point. And the real power of this test is in serial monitoring, meaning we run it again and again and again over time. And if that number goes up, the cancer activity is likely increasing. If it goes down, we’re likely suppressing the tumor activity. And if it stays flat or falls, that’s telling us that the disease is responding. So this is now in the blood. We have an actual fingerprint and every test from here forward will be compared to this number. Now let’s talk a little bit about this because I was not familiar with this test at all. I wasn’t sure what to expect. I wasn’t sure what to do with it. I did not order this test. He’s working with Inveda Medical and they are fabulous over there. I will tell you that from the beginning. This is coming from a practitioner and from a mother-in-law. They were absolutely wonderful to us. So when I saw this North Star, I didn’t know, should it be zero? Should it be a hundred? And when I talked to the doctor, he said, Dr. Deb Muth 15:29This number is actually really good. An average person walking around who’s never been diagnosed with cancer, who doesn’t have cancer, their number will be between 75 and 100. Cameron’s was 13. I think that’s fantastic. But what was the first question that went through my head? It’s probably the same question that you guys are doing. How can he have cancer with a number of 13 when it’s less than the normal average? And if we’re supposed to use this to track what’s happening with his cancer, how are we going to do that once we remove the cancer? Is this number going to go to zero? And it could possibly do that. And we may not be able to use this to track whether or not the disease is actually gone. But what we can do is use this to track over the course of his lifetime to see if the cancer cells are coming back long before we detect them on imaging. And that’s the huge part of this.So this is not a test that just anybody should go out and get because you’re worried about cancer. It is a test that should be done in somebody that is already diagnosed with cancer. So let’s start by making sure we explain that, okay? So imagine if every time your cancer cells are active and they’re shedding and they’re multiplying and they’re fighting back, they’re leaving a signature in your blood not just any signature, but a specific chemical tag that says, cancer’s here. That’s what the North Star Response Test reads. Those tags across thousands of locations and gives us a single score. So we track that score over time like a thermometer for your tumor. If it goes up, we get concerned. If it stays stable or goes down, we celebrate. And we can catch a change in the blood often months before it will show up on a scan. Pretty important when we’re talking about surveilling somebody for cancer returning, when we’re worried about it, and everybody knows the cancer patient is always worried after they get that clean bill health that something’s gonna come back, and most of the time they’re told that there is no way for them to determine that or know that from a blood test. And here is the blood test that can tell us, yes, it can. Dr. Deb Muth 17:51So I would really encourage you guys to talk to your oncologist about this. If you can’t find an oncologist that will do this, talk to an integrative cancer doctor. They will most likely be familiar with it. If not, ask them to find it for you and order it for you. So next, let’s talk about that genetic blueprint because North Star Select is a different test also by billion to one run on the same blood draw, but this one is doing something completely different. This is a comprehensive genomic liquid biopsy. Liquid biopsy just means blood tusks, meaning it’s looking for specific mutations in 84 cancer related genes, all from a blood sample, no biopsy needle, no surgery, just a blood draw. It looks for CNVS, single nucleotide variants, tiny one-letter typos in the DNA code. It looks for indels, small insertions or deletions in the DNA. It looks for copy number changes, the sections of the genomes that are duplicated or deleted. It looks at fusions. So when two genes incorrectly link together to create a dangerous hybrid, MSI status, micro satellite instability, which tells us whether immunotherapy is likely to work. And it has extraordinary sensitivity. It can detect a mutation that represents as little as 0.15 % of cell free DNA in the bloodstream. That is an almost impossibly small signal in the ocean of genetic noise. So what did this show for Cameron? This is where Cameron’s case gets clinically fascinating and where it tells the story of how his cancer is being held in check. Two major mutations were identified as actionable. One was called CRAS G12C. Dr. Deb Muth 20:11And it’s a variant-ELI fraction at 0.1%. Now, CRAS, if you’ve spent any time in integrative oncology, you’ve heard this name. CRAS is one of the most well-known oncogenes in cancer biology. Think of it like an accelerator pedal in the car. In a healthy cell, CRAS pushes the cell to grow when it receives the signal to do so. And then it stops. In cancer, crass gets stuck in the go position, like on the accelerator, foot on the accelerator, to the floor, going as fast as you can around that track, right? But it’s stuck there permanently. It doesn’t turn off and it’s supposed to be turning off. The G12C variant specifically is a mutation at a very precise location. Position 12 of the CRAS protein, where a glycine is replaced by cysteine. And this matters because CRAS G12C is now a drugable target. There are FDA approved drugs specifically designed to lock this mutation into its inactive state, essentially putting a foot on the brake. Now those are drugs like, and I’m gonna slaughter these names, Sordisib, a brand name is Lumacras, and Atacras, the brand name is Crastol. Neither is yet FDA approved for breast cancer, but they are approved for lung and colorectal cancer with CrasG2C. And Cameron’s tests identified 10 active clinical trials within a region that he could potentially qualify for with this mutation. The fact that his CRAS G12C is circulating at only 0.1%. That is a very low fraction. We call that a VAF, V-A-F, very low fraction. And it tells us something important. It means that this mutation is present in a small subclone of the tumor. It’s not the overall tumor burden. So either way, when we identify, we know it’s there. Dr. Deb Muth 22:37We can catch it and we can watch it. Now, here’s another interesting thing that we saw. His TP53 was at 0.23%. This is a tumor suppressor gene, the guardian of genome. And this gene is responsible for telling damaged cells to either repair themselves or self-destruct. And when it mutates as it is here in the position R196Q, that guardian goes off duty. The cell no longer has a reliable mechanism to prevent uncontrolled growth. So TP53 mutations are present in roughly 50 % of all human cancers. And there’s currently no FDA approved drug directly targeting the TP53 but there are clinical implications. TP53 mutant tumors may respond differently to chemotherapy and several investigational approaches, including TP53 vaccines and aurora kinase inhibitors are under active investigation. So we are seeing things happen in this part of cancer right now. Now there’s something called the VUS list and we are watching This is what we’re watching. beyond those two actionable mutations, NORSTAR Select identified what we call variants of an unknown significance, VUS, adenocarcinoma of an unknown significance, ACUP. These are mutations where we don’t yet have enough clinical evidence to determine whether they’re driving cancer or not, but we watch them. So on our mutation list was CDH1, a gene linked to hereditary gastric and lobular breast cancer, CDKN2A, a tumor suppressor cell cycle regulator, CDK12, involved in DNA repair, EGFR, ERBB, this is HER2 receptor, tyrosine kinases. Dr. Deb Muth 24:55I thought this one was pretty interesting since he had an IHC that showed a three plus HER2, but then when we confirmed it with FISH, FISH showed that was negative, but now we’re actually seeing genes expressing this HER2. So is there a HER2? Is there not a HER2? This is really important because if we don’t get these diagnoses right in cancer the first time, people will spend months and years treating the wrong type of cancer with the wrong type of medication. And this may be in part why some people do better than others. If we get it right out of the gate, they do good. If we don’t get it right out of the gate, they don’t do so good. Very important to have the actual genetic makeup of the tumor that’s growing in somebody. Now last, we have something called Notch C1, NRAS and RAF1. These are key pathway components. Now all of these were at very low baffs under 0.5%. These are just whispers, not shouts, but whispers that this cancer is excreting, but your body is listening. We have to be listening. We have to be able to watch these things and monitor these. Now here’s another note of clinical interest. It was an androgen receptor positive cancer. So also detected as a VUS.We know from tissue pathology that Cameron’s tumor was androgen receptor positive. So seeing this in circulation confirms that this AR expression of the cells are present in the bloodstream and that an anti-androgen approach remains worth considering. What that means is suppressing the testosterone. What all of you know I’m about ready to say is that I hate ever suppressing hormones, especially in a 38 year old male. That is not necessarily a good thing. So before we go suppressing hormones willy-nilly, we have to know that it’s the right thing to do. And we have to be able to combat all of the complications that are going to result of that. A 38-year-old male with no testosterone could lead to heart disease down the road, could lead to bone loss, could lead to dementia, Alzheimer’s. Not to mention the sexual side effects that are going to be present. And in a man that is very, very Dr. Deb Muth 27:20Difficult for someone to manage. So you have to be very specific and you want to be very, very diligent about what you’re doing in these cases like this. Now the MSI status was not detected. This tells us that cancer is not a microsatellite instability high, meaning that standard monotherapy may have a lower baseline response of probability and the strategic integration that we’re working with with in Vita could create an immunogenesis genicity becomes even more critical. So immunotherapy is going to be very critical in a cancer case like this and working with somebody that understands that and can carefully navigate that, especially if you have an autoimmune disease like Hashimoto’s or lupus, this is all very, very pristine and has to be looked at very carefully and done very diligently in order for somebody to do this without overstimulating that immune system and causing more problems. So when we looked at the blood and found this DNA fingerprint of the cancer cells circulating in the body, from that, what we see exactly is the genetic switches that are stuck on. They’re stuck on in the wrong position. This tells us which drugs were designed to fix exactly that problem. And it opens the door to clinical trials built for these specific mutations. It also gives us a list of things to watch for over time. And if one of those tiny little signals starts to grow, we know that cancer is gaining a ground in that area. And if it shrinks or disappears, we know we’re winning. This is like, I cannot tell you how exciting this is in the cancer world and the medical world because this is really pristine cancer therapy that we’re dealing with here. And to be able to have this is just so important to life saving events in treating cancer. So. Dr. Deb Muth 29:41Let’s talk about something called the Dittar Chemoscale. This is the battle before the battle. Okay, so I’ve saved the most remarkable test for last, and this is one from a company called Dittar Cancer Genetics. They’re based out of the UK. They are CAP and CLIA certified, which means it meets the rigorous standards required for clinical laboratory testing in the US. And this test is called the ChemoScale. And it is a live cell chemosensitivity assay. So let me explain exactly what that means because it sounds complex, but the concept is actually quite elegant. When we drew the blood from Cameron, the Dittar’s laboratory isolated what are called circulating tumor associated cells or CTACs. And these are actually living cancer cells and they’re associated cells that are traveling through his bloodstream. Excuse me. So let’s think about that for a moment. Real live cancer cells isolated from a blood draw. Those living cancer cells were placed into a lab environment and exposed to over 70 different drugs, both conventional chemotherapy agents and what we call repurposed drugs. I’ll talk more about those in a minute. The lab then measured how many of those cancer cells were killed by each drug expressed as a percentage of cell death. So the scale runs from zero to a hundred and below 25%, that drug doesn’t work well against any type of cancer in that person. Might work great in somebody else, but in that particular person’s cancer that they have, it’s not gonna work so great. Anything that’s 25 to 50 % is intermediate and above 50 % is a high response. And that’s really where Dr. Deb Muth 31:43we want to be. We want to see anything higher than 50 % because that’s a great medication that can be used to kill the cancer. This is not a theoretical test. This is not based on tumor’s genetic sequence and the computer algorithm that predicts the drug response. This is a HIS actual tumor cell being killed or not being killed in real time. That is the difference. So in traditional chemotherapy, we have our protocols. If you have triple negative breast cancer, if you have HER2 positive breast cancer, if you have prostate cancer, if you have colon cancer, here’s the protocol that you’re going to use because that’s the type of cancer you have. That’s what’s been studied. Now, the problem is most of these cancers have mutated over time, especially depending on how long they’ve been in your body, because that’s what they do to try to survive. They have to change so they can survive because your immune system’s constantly trying to kill them. And so this is a really important thing. And if we don’t take an individual into response or into our thought process when we’re creating these protocols, we may give a drug that doesn’t work at all towards that cancer and you just wasted seven cycles of chemotherapy with a drug that never would have worked in the first place or had such low resistance to it that it’s now just created side effects for you but did nothing to the cancer. And then we pull out another drug and we try that. And then we pull out another drug and we try that. Instead of us knowing precisely what we can use and what we can do. And this goes for both the conventional world and the alternative world. In the alternative world of cancer, we use things like IV vitamin C and tumeric and lately ivermectin and fenbendazole and mendendazole and all kinds of other things. And if we are not truly aware that this is going to do anything, we could be wasting somebody’s time and money. So I love that this test is available. I want to walk you through a little bit about what Dr. Deb Muth 34:01we are what we saw in our case, because I think this can make a big impact on people to ask the right questions. So this particular blood test looked at several different drugs. Cameron had sensitivity from 44 % up to 61 % on different medications. Now he was really lucky. The three main drugs that they would use to treat his cancer he had greater than a 50 % response to. So that was great. However, the drugs that were recommended for him to use out of the gate had less than 50 % activity. So he would have had one drug that was really good, one drug that was not so good. And we don’t know what the outcome would have been, right? So I think this is such an incredible, incredible test to have done. This is critical friends. I’m telling you if his oncologist had chosen the two drugs based on the general guidelines for his tumor, his cells would have largely not survived. But because we ran this test, we know. So we know to avoid the drugs that won’t work and we focus on the firepower where it really counts. So I want to also talk about this repurposed drug result because this is where it gets integrated for us. Now, this section is what I want everyone in our community, our Let’s Talk Wellness community, our members to understand. This is where conventional medicine and integrative medicine intersect in a peer-reviewed clinical validated way. So the Dittar test looks at live cancer cells against what they call repurposed drugs, meaning pharmaceuticals and natural compounds that were developed for the purposes, for other purposes, like it could be an antibiotic, it could be an herbal medicine, it could be all kinds of things, vitamins, whatever. But they have demonstrated anti-cancer activity in research. And when we’re talking about integrative medicine, this is a lot of where we get Dr. Deb Muth 36:26The integrative protocols from because these particular drug compounds are known for having anti-cancer benefits. And so that’s how integrative protocols get developed. But again, it could be just like medication, like cancer drugs. If your body doesn’t have a susceptibility to it, then you’re using a product that’s not necessarily going to work. And we all know we cannot take everything that somebody recommends just simply because it has an anti-benefit to whatever it is we’re treating. There’s only so many supplements you can take. There’s only so many things you can do before you get burnt out on taking it. We call it supplement fatigue. And so we want to be very precise with what we’re doing and target this very specific area. So one of the things that showed up really, really well for our case was artemisium, sweet wormwood. It’s an anti-malarial drug that has very potent anti-cancer effects. Now I found this extremely interesting in Cameron’s case because he does have a positive tick-borne illness called Babesia. And this is one of the things that we use to treat Babesia. The other thing I think is very interesting in this case is we are studying how parasites affect cancer these days. And that’s how Ivermectin, Fenbendazole, and Menbendazole have all gotten thrown into the treatment of cancer. And so for this drug or this herb to be sensitive to this type of cancer is really intriguing to me in the world of parasites and how parasites are truly decreasing the body’s immune system and causing cancer to grow. Another thing that worked, showed up really well for him was Valprolac acid. It’s an anti-seizure drug with HDAC inhibitor properties, and this disrupts cancer cell gene expression. There was a soy formula that showed up really well. Naltrexone, you guys have heard me talk about low dose naltrexone, LDN. This actually stimulates an endogenous opioid immune response feeling, and this drug actually showed up really well. Dr. Deb Muth 38:49Something as simple as quercetin. It’s an anti-inflammatory. This is a crass inhibitor in some studies. So this is really important. I’m sure most of you have heard about the benefits of green tea and green tea also actually has anti-angiogenic or anti-cancer benefits to it. Hydroxychloroquine, very popular drug. It’s another anti-malarial drug. So again, now we have two anti-malarial drugs that are susceptible to this type of cancer. And on top of it, he has a positive babesia test. So just saying, you got to connect the dots sometimes. You got to think outside the box sometimes. Metformin is very well known as a anti-proliferative in cancer. We use it to suppress the sugar because sugar feeds cancer. Nobody should be eating sugar if they have cancer. So this one showed up as well. And then CBD, we all know of the benefits of THC, the Rick Simpson oil, and CBD can be tested to see if that is beneficial to a particular cancer cell. This is different than THC. THC works very differently in cancer. CBD is your healthy component of it. It’s the part of the marijuana plant that does not make you high. So very important here. So now let me be very clear, because I always try to be very clear. This is not FDA approved. I’m going to repeat that. This is not FDA approved. This test is a laboratory developed test, not FDA cleared. These results represent in vitro testing, meaning in a lab, not inside the human body. And the results can differ in what we call in vivo, inside the body. And this is why I always say work with a qualified clinician who can interpret these results in full clinical context. But here’s why this matters. We now have evidence, live evidence of a cancer cell that shows sensitivities to compounds that are accessible, relatively safe, and some of which he may already be using, which some of them we were. Dr. Deb Muth 41:13We were already using some of them, which made us sit back and say, this cancer has been in there for two years. If it’s a triple negative breast cancer, it’s supposed to be an aggressive breast cancer that should have spread to a different organ already after two years. It is not, it has stayed in one spot. Also interesting in this case is that there is no breast tumor that they could find anywhere. This was all confined to the axilla into the lymph node. So to have this growing for this period of time with such a small tumor marker number, that 13 that we talked about in the North Star test originally, and to see some mutations, there’s a lot of questions to this particular case. And there are lots of questions to everybody’s cancer case. They are not all straightforward cancer cases. So this is what’s important to understand this fingerprint of these cancer cells so that you can identify exactly, exactly what’s going on and treat it exactly the correct way. Super important. So this kind of information gives us the direction in an integrative protocol. It’s not guessing. This is not eat more tumor, I can hope for the best. This is personalized tumor specific precision guided integrative oncology. It is very precise. There are several countries, several clinics like this around the country that offer this type of therapy. If it’s something that you’re interested in doing, I would encourage you to look at in Vita Medical. Hope for Cancer is another great facility. There are several great facilities around the country. Like I said, that could put together an integrative approach for you if this is something that you are thinking about doing. If you’re looking for answers, if you’re in stage four or stage three and you are not getting the results that you want to get, you want to look at a different approach. You want to do a combo approach of integrative medicine and traditional medicine and alternative medicine. Dr. Deb Muth 43:37I think this is so important to look at and have experts on your team. You know, in our case, Cameron’s cancer is very complex. It’s genomically aggressive in its presentation, yet it’s not progressing to distant areas, which is so wonderful. And I want to be careful here. I can’t tell you with certainty that this is any one thing. Biology is complex. Cancer is adaptive. It’s trying to survive. That’s what it is supposed to do. It is changing its shape. It’s changing its genetic structure. It’s changing everything to try to survive and try to hide against your immune system. Now we are not even close to the finish line in our journey, but what I can tell you is that what the integrative precision approach has done that standard care alone might not do. I can tell you that today and I will share our journey along the way for any of you that are going through this that want to look at a different approach as well because I think it’s important to have this information. So first of all, we know the tumor’s fingerprint. North Star response gives us that TMS score. so we can track it over time. And if the cancer tries to gain ground, we’ll see it in the blood before a scan, we’ll show it. We know the cancer’s genetic vulnerability. We know how to handle the DNA now. We know the watch list of things to look for. And when those signals start to grow, we have a roadmap of how to address it next, how to change it. We know which drugs will automatically work against the tumor cells. We’re not guessing based on a tumor type. We tested the cells. We know how many drugs in the commercial world and in the repurposed world will and will not work. And this is going to guide the treatment protocol that we walk forward with. So we’re not giving him drugs that won’t work or have a low response. Dr. Deb Muth 45:55We’re avoiding them completely and that matters because every ineffective drug is a dose of toxicity with no benefit. There is no lie to this. Chemotherapeutic drugs are toxic. That’s how they kill the cells, but they kill the good cells and the bad cells. And if we can avoid using a drug that’s not going to work, that is so important. And then we’re layering in those repurposed and natural compounds with proven activity against specific cells. This is not complementary fluff. This is biologically active tumor tested precision medicine. Very, very important. So here is what I need you all to know and what I want you to walk away with today. If you or someone you love is facing a cancer diagnosis before treatment starts, before the first infusion goes in, I want you to ask these questions so quick. Go grab something to write with. Pause this if you need to, because this is really, really important for you to do that. And we’re going to take a break for just a second while you guys go and do that. We’re going to give you a word from our sponsor, and then we’re going to come back. And I’m going to give you the four questions that I want you to ask specifically of your medical team so that you have the answers and the ammunition that you need to work with. So we’ll be right back. Dr. Deb Muth 47:29All right, everybody, welcome back. I hope you got your pencil, your paper, your pen, your phone, whatever you’re going to take notes with because this is important. So I’m to give you four questions that I want you to ask your medical team before you get started. Question one, can we do a chemo sensitivity test before we choose a chemotherapy regime? Ask specifically about DATAR, D-A-T-A-R. cancer genetics, Oncostat Plus, or a similar functional chemosensitivity platform. Very, very important to ask those specific things. All right, question two. Can we do a comprehensive liquid biopsy to identify actionable mutations and monitor tumor burden? Ask about North Star Select, Billion to One, Guardian 360, or Foundation One Liquid CDX? I’m gonna say those for you one more time, because I said them kind of fast. North Star Select by Billion to One, Guardian 360 or Foundation One Liquid CDX? Okay, question three. Can we establish a baseline tumor methylation score, TMS, so we have a surveillance marker to track over time? and ask specifically about the North Star Response Test. All right, question four. Is there an integrative oncology center that can layer precision guided natural compounds alongside conventional treatment? Research institutes like Inveda Medical Center, CTA CA Integrative Medicine, or Hope for Cancer, these people are doing integrative medical miracles. Let me tell you, I have researched every one of them. I have spoken to each of them individually before we made our decision of who we were going to work with. They are all fantastic. You want to work with an integrative nurse practitioner who understands oncology. And if you’re working with an integrative practitioner, you want to ask them these same questions about this test so that you can get the best outcome. Dr. Deb Muth 49:56For what you’re dealing with. You are allowed to ask these questions. You are allowed to want more information from that protocol that was designed for the average patient. You’re not average and your cancer is not average either. And your care doesn’t have to be. You do not have to settle for the same thing that the person sitting next to you in the IV suite is dealing with when you both have different cancers excreting different genetic material. This is so incredibly important. want to make sure you understand precision medicine is what changes the lives for people every single day, every single day. So I started this episode by telling you about a 38 year old man with a cancer that baffled conventional medicine and integrative medicine, an occult primary that was not found complex genetic genomic profile, a presentation that in many hands might have resulted in a one size fits all treatment protocol and a prayer. And instead we ran the tests, we mapped the fingerprint, we watched the cells, we guided the protocol, and we are still fighting with precision, with data, with intelligence. This is what Let’s Talk Wellness is all about not giving up. This is what not accepting we don’t know as a final answer and demanding the level of scrutiny and personalization that every cancer patient deserves. So if this episode resonates with you, please share it because somewhere out there, there is a person who is about to get the wrong chemotherapy because no one ran the right test. And maybe, just maybe, that This episode will be the reason someone asks the right question at the right moment. If you’re going through something like this, you need a group, you need somebody to connect with, please join our free Facebook group called Seen At Last. It is where we support one another, we share this information, we share knowledge, and we help people for free support and ask the right questions. Dr. Deb Muth 52:23And if you’re inclined in your heart to pray, pray for Cameron, we could use every ounce of prayer. If you are in a position where you can help support this journey financially, we do have a fund going in free funder. I can post the link below. Every little bit helps. If you have $5, $500, it doesn’t matter. We’re raising money for this treatment. And along the way, I am documenting every step of what we’re going through so I can provide more episodes like this for you guys to share the outcome and share what our journey is like so that it can help the next person along. I really always believe that whatever happens to us happens to us because we’re meant to share it. That’s why I’ve shared my personal journey. I’m sharing his personal journey and we want to help other people. So until next time, I’m Dr. Deb. Keep asking questions, keep advocating, and never ever accept being unseen.The post Episode 274 – Stop Guessing on Chemotherapy: The Live Cell Test Most Doctors Miss first appeared on Let's Talk Wellness Now.

Explore a personalized approach to Low-Dose Naltrexone (LDN) with Dr. JJ Allen on the LDN Radio Show. Discover his journey from engineering to pharmacy, advocating for foundational health, lifestyle changes, and evidence-based nutraceuticals. Learn about optimizing key nutrients and the nuanced titration of LDN for autoimmune conditions and long COVID.

This professional discussion explores the innovative microdosing protocol for Low Dose Naltrexone (LDN) developed by Dr. Norman Marcus. The conversation highlights its effectiveness in managing autoimmune diseases, cancers, and particularly Mast Cell Activation Syndrome (MCAS). Learn about the challenges and advancements in LDN therapy and its growing applications.

This episode of the LDN Radio Show features Deborah sharing her journey with peripheral neuropathy and her positive experience using low-dose naltrexone (LDN). Host Linda Elsegood also discusses her own experiences with chronic pain conditions and the benefits of LDN. The conversation touches upon gut health, the FODMAP diet, and the challenges of accessing and raising awareness for LDN treatments.

In this live DNS Podcast recorded on 6/3/2026, host Christina Rollins is joined by a multidisciplinary oncology team to explore how strong interdisciplinary relationships optimize enteral nutrition care.  This session will examine real-world strategies for improving collaboration across disciplines, from feeding tube decision-making and placement to monitoring, troubleshooting, and care transitions. Panelists discuss communication gaps, role clarity, shared decision-making, and leadership behaviors that foster a culture of coordinated, patient-centered care. Speaker Bios:Gabrielle Raucci, MS, RD, LDN is an oncology dietitian at OSF Cancer Institute, providing nutrition care across the cancer continuum. She specializes in enteral nutrition support and feeding tube management, co-developed an enteral nutrition skills lab for dietitians, and serves as President-Elect of the Central Illinois Academy of Nutrition and Dietetics. Gabrielle earned her master's degree from Illinois State University and was recently named Central Illinois Recognized Young Dietitian of the Year.Jeanna Brouwer, RD, CSO is a board-certified oncology dietitian with more than 13 years of experience supporting patients throughout cancer treatment and survivorship. She has developed numerous educational programs for clinicians and is especially passionate about enteral nutrition, patient advocacy, and improving feeding tube processes from planning through home initiation.Jessica Williams, APRN is an advanced practice registered nurse with otolaryngology at OSF HealthCare. She specializes in ear, nose, and throat care, partnering with patients to identify underlying causes of their conditions and develop individualized, evidence-based treatment plans focused on compassionate care.Nicole McKinley, MS, CCC-SLP is a speech-language pathologist at OSF St. Francis Medical Center with more than 30 years of experience in head and neck cancer, voice, and swallowing disorders. She serves as OSF's head and neck cancer content specialist, mentors clinicians and students, and is dedicated to restoring voice, swallowing function, and quality of life.Catherine Bailey, RN, OCN is an Oncology Nurse Navigator at OSF Saint Francis Medical Center specializing in head and neck cancer survivorship. She helped develop OSF's START survivorship program and supports patients through education, support groups, and care coordination. Catherine has published and presented nationally on oncology navigation, survivorship, and advance care planning.Learn more about all things nutrition support at dnsdpg.org.

Check Out BioVitalis Peptides: https://biovitalis.org/ (Use Promo Code: GSD10 for 10% off)   Check Out Jim Brown's Substack Blog: https://substack.com/@forj   *Disclaimer: This NOT medical advice. Please make sure to seek your own medical professional for medical advice.   On this Podcast we break down our personal "Forever Peptides" vs the Peptides we cycle and/or the peptides we use at specific times of the year or as needed. We also dive into questions we received over the past week on peptides, nutrition, TRT, etc... If you have any questions, please send me an email Joshua@GSDMode.com and here are the questions we jump into this week:   -Question: When are you guys going to do a gear podcast? (I asked if He had any specific questions on "Gear") yeah I'd say a good first cycle , thoughts on tren ?, is it worth it low dose maybe ? Mast .   -Question: question: Your thoughts on using Trenbolone Enanthate at 150mg/week, instead of using Testosterone Cypionate 150mg/week for TRT?    Question: Hey guys! Once again thanks for all the great info! I just had my shoulder surgery yesterday and started my aggressive healing protocol this morning. I am in an adductor sling for the next 6 weeks. I start PT in a week, but I can take my arm out to breath and clean in 72 hrs. Can I pin my lats or tricep? I want to administer the bpc as close as possible but atm I can't seem to do it one handed and in my current state. I have been sticking to my stomach but I know the closer the better.   Question: Really appreciate all the great practical information. Could I please have your opinion on the compound Tesofensine. Any info will greatly appreciated. Thank you   Question: Hi Josh, Hi Jim. Amazing work all the time Gentlemen! Have you heard of / researched taking LDN (low-dose Naltrexone) for inflammation reduction? And, have you heard of / researched FLGR-242, a modified version of Follistatin-344, which has been available to the public since approximately November of 2025.   Question: I've been taking 200 mcg of cjc 1295 and 200 mcg of ipamorelin before bed 5 days on and 2 days off for about a month. I was not sleeping well on the nights i took it. 2 days ago I started taking1mg of tesamorelin and 200mcg of ipa before bed and cjc and ipa in the morning. I woke up with a headache both mornings. I was take half the amount of tesa and see what happens. Just curious what you thought was causing the headache. Thanks for all the good info guys!   Question: I've been on Reta for 4 months and have lost 15 pounds and 2 belt sizes, but my blood pressure is up and was a little high when I started it. If I stop Reta what should I take instead? I am going to start Tesa and wolverine stack for injury and to address gut problems. Still need to lose 30 pounds from waist up! 57 years old. Thanks!   Question: Hi guys! You talked about SS-31 and MOTS-C and running one before the other. I'm currently running SS-31 and planning to add in MOTS-C after a few weeks. I'm hearing that adding in NAD+ on opposite days of MOTS-C is beneficial. Have either of you done this? And if so, would you suggest that I add in the MOTS-C first and then a couple of weeks later, the NAD+? What are your thoughts? Thanks so much!   Question: Is there anywhere to look at the Reta statin data for plaque? My buddy had a widowmaker at 46 last month; it has me worried about my heart health at 54. I have a mild blockage in my LAD. I am on Tirz and a statin as is. If there is a way to reduce it at all I would be willing. Thanks!! Love the show!

Send us a message!Ever thought about working in sports, but not sure how to break into the field? In this episode our guest in sports dietitian Emily Kaley, MS, RDN, LDN, CSSD, ISAK 2! Emily shares about her career path, advice for students and how you can join her mentorship program!Emily Kaley, MS, RDN, LDN, CSSD, ISAK 2, is a Performance Dietitian with experience working across professional, collegiate, and Olympic-level sports, including Team USA Track & Field, Team USA Swimming, the New York Knicks, New York Rangers, New York Liberty, New York University, Chicago Cubs, New York Mets, and Washington Nationals. She has built and implemented sports nutrition programs that support athlete fueling, recovery, health, and performance in high-demand environments.Emily earned her Master's degree in Sports Nutrition from University of Colorado Colorado Springs, a Bachelor of Science in Nutrition and Dietetics from Simmons University and completed culinary school in Manhattan, giving her a strong foundation in both nutrition science and real-world food application. She specializes in translating complex sports nutrition concepts into practical, performance-focused strategies athletes and teams can apply.She currently runs a Performance Nutrition private practice in Brooklyn and mentors aspiring and practicing sports dietitians through The Academy for Sports and Performance Dietitians. A lifelong athlete, Emily earned her black belt at 15, played collegiate lacrosse, and has competed in the New York City Marathon and HYROX NYC. You can find Emily enjoying time with her family and eating her way through NYC.Emily's Mentorship Program is dedicated to educating, mentoring, and empowering the next generation of Sports Dietitians. Through expert-led courses, real-world insight, and professional mentorship, the Mentorship Program helps aspiring and practicing Sports Dietitians better understand the role of a Sports Dietitian and build the knowledge, confidence, and connections needed to succeed in the field of sports and performance nutrition. Contact Emily at emily.kaley@gmail.com if interested!

In this Nutrition411 podcast episode, Lisa Jones, MA, RDN, LDN, FAND, speaks with Wayne T. Ho, MD, and Vance L. Albaugh, MD, about how clinicians can improve obesity care for men by recognizing obesity as a chronic, relapsing disease and moving beyond outdated assumptions about willpower, protein intake, and scale-based success.

In this episode of the Hormone Genius Podcast, the hosts sit down with Dr. Marina Suri, an OB-GYN with more than 30 years of experience in restorative reproductive medicine and women's health. Together, they explore a refreshing and hopeful perspective on fertility, longevity, and what women can do naturally to support their hormone health and reproductive lifespan. Dr. Marina introduces the idea of “biological age” versus chronological age. While we cannot stop time, she explains that the health of our bodies is deeply influenced by lifestyle choices. The same habits that support longevity. The conversation dives into practical, foundational approaches that often get overlooked in conventional medicine. Rather than focusing first on expensive biohacking trends, Dr. Marina encourages women to start simple: eat whole foods, reduce ultra-processed foods and sugar, move the body regularly, and prioritize nutrient sufficiency. She shares how deficiencies in nutrients like vitamin D, B12, magnesium, and omega-3s are incredibly common in her patients and can significantly impact hormone health and fertility. The hosts also discuss the overwhelming amount of health information women encounter online today. Dr. Marina reminds listeners that the basics matter most. A Mediterranean-style diet, reducing inflammatory foods, regular exercise, and stress management are still some of the most evidence-based ways to improve fertility and overall wellness. Another major topic of the episode is low-dose naltrexone (LDN), a therapy gaining attention in restorative reproductive medicine.More recently, she has seen promising use in fertility support, particularly for women with inflammatory conditions such as endometriosis and PCOS. She discusses both the potential benefits and considerations of using LDN, including common side effects like vivid dreams and sleep changes. The discussion also highlights the growing concern surrounding endocrine-disrupting chemicals in modern life. From plastics and water contaminants to personal care products and cleaning supplies, Dr. Marina explains how environmental toxins may be impacting fertility, hormone balance, and even sperm counts. She shares practical ways women can reduce exposure without becoming fearful, including using water filters, cleaner products, and tools like the Environmental Working Group's Healthy Living App. The episode closes with a beautiful reflection on body literacy and the importance of women understanding their cycles and hormones. Dr. Marina encourages women not to take fertility for granted and to become more in tune with the natural rhythms of their bodies. Her mission is simple but powerful: to help women understand that they are not powerless when it comes to their health and fertility. This episode is packed with practical wisdom, encouragement, and empowering reminders that small lifestyle changes can truly transform hormone health, fertility, and long-term wellness. Interested in being a Podcast Sponsor with THE HORMONE GENIUS? Check out these links next to get more detailson our SPONSORSHIP VISION! PODCAST PARTNER: https://docs.google.com/forms/d/e/1FAIpQLSdffY6WpATSUZfVtaQDlgCH1TDvvR5o3u-1G_sxUzQ0iRgHqg/viewform MONTHLY SPONSOR: https://docs.google.com/forms/d/e/1FAIpQLSeBmq62f7FcAs6aGqD_2wrHyWlXRm66bhzvqF2M1Pal5nkGyA/viewform BRAND PARTNER: https://docs.google.com/forms/d/e/1FAIpQLSfBu46XqvMbmi8dqt8LBzUE0r22Gj39Ou9tbXSeN6d8-G5qaA/viewform We love partnering with brands that align with our mission of empowering women through hormone education and whole-body health. Visit WeHeartNutrition.com and use code GENIUS for 20% off your first order. The information shared on the Hormone Genius Podcast is intended for educational and informational purposes only and should not be considered medical advice. The views and opinions expressed by guests are their own and do not necessarily reflect those of the podcast hosts or sponsors.

Ep. 108- Silent Reflux (Laryngopharyngeal Reflux) with Dr. Inna Husain, MD by Erin Kenney, MS, RD, LDN, HCP

A young associate, from what I could gather, had been on the job for 3 days, and was asked to go over to another building and help load out D-Containers. They were quite shocked to learn they were not the large metal containers, as she put it, that looks like trailers. She asked if I'd ever seen such.  It just so happens that I've worked a lot with different containers earlier in my career.   Now when most people hear the word container, they think about those giant steel boxes stacked on ships crossing the ocean. But containers are really everywhere. From a D container rolling through a retail grocery warehouse, to an EH container packed with heavy product, to lift vans moving families overseas, all the way up to 45-foot, and even larger, high cube ocean containers arriving from around the world. There are so many different types of containers. They organize freight, help protect the product Increasing productivity and Improving cube utilization, and speeding up transportation.  And if you've ever worked around them, you already know containers aren't just boxes. Some are designed for stacking. Some for rolling. They even have some refrigerated products. I've seen several different ones for for export shipping.   So today, let's talk about containers. The small ones, large ones, reusable ones, the refrigerated ones, and the giant steel containers that changed global commerce forever.  Let's start with the containers many warehouse associates know best. The D containers, E containers, EH containers, and the LDN containers. Now depending on the operation, the exact sizes and names may vary slightly, but in grocery, foodservice, retail, and large distribution environments, these are usually large reusable, pallet or rolling containers designed around warehouse productivity systems. These are not the little plastic totes on our conveyer tracks.  Let's start off with the D Container. I've banded and strapped many a D container in my day.  If you've spent time in grocery or foodservice distribution, especially in the produce world, you've probably loaded up hundreds of D containers in your career. The D container is one of the workhorses of warehouse distribution. An absolute time saver. Typical dimensions are often around 48 inches long, 40 inches wide and anywhere between 36 to 48 inches tall. Anybody want to guess why 48 by 40. Yep, the size of a typical GMA, or the grocery manufacturers association pallet. Most are built with heavy-duty cardboard or plastic with reinforced bases, large caster wheels for the rolling models and some stackable designs as well. Many operations load them with 1,000 to 2,000 pounds of freight. I commonly see D containers used for mixed product selection, cooler operations like produce, think of like watermelons, pumpkins, melons, things like that. They are good for returns and repacks too. If you've seen those commercials or ads for buying a pallet of returned product, they may ship it to you in a D container.  A container can truly change the workflow. Using the right container is important. The size of the container affects our picking speed, trailer cube, stacking patterns, conveyor systems, even different slotting strategies, and labor productivity. Operations teams don't just pick containers randomly. There’s engineering behind every inch of that design. And from a safety standpoint, D containers demand respect. Once they're fully loaded, stopping distance changes, our pushing force is increased, visibility and control changes. Anybody that's ever lost control of a loaded D container on an incline knows exactly what I'm talking about!  Next up are the E containers. Now the E container is usually taller and designed for higher cube utilization. Typical dimensions are again around 48 inches by 40 inches wide, but  around 50 to 60 inches tall. You'll see E containers heavily used in, again, grocery distribution, some types of retail replenishment, and both cooler and freezer environments. I mentioned respect and safety earlier. That extra height changes everything operationally. Now we're talking about a higher center of gravity, reduced visibility and an increased tipping risk. A poorly built E container becomes dangerous quick. Especially if heavy product gets stacked high or product shifts during transportation.  Now let's move on to the EH container. The heavy-duty version. These containers are built tougher and stronger. More reinforced. And designed for heavier freight applications. The typical dimensions are often 48×40 and 60 inches tall or greater. Many operations safely load 2,000 pounds or more into an EH container.   You'll commonly find EH containers in freezer operations, meat distribution, industrial warehousing, manufacturing, and such. And once again, the container itself becomes part of the safety conversation. Because now we're discussing pinch points, rolling weight, dock plate safety, caster failures, and freight shifting. Especially in freezer environments where condensation freezes, wheels become harder to control, and any plastic can become brittle.   Let's see, what’s next, the LDN containers. These are often longer, deeper, high-capacity containers designed for heavy environments. Typical dimensions may range from 48 to 60 inches long, 40 inches wide and 60 inches or taller . These are commonly seen in cross dock operations, route staging and high-volume distribution centers and these containers are built around one thing, cube utilization. Empty space cost money right. Every inch matters. In the trailer, on the dock, in reserve storage and on conveyor systems. The better we use cube, the more efficient the operation becomes.  Now let's talk about something many younger warehouse associates may never have heard of. The lift van. Before standardized ocean containers became the norm, lift vans played a huge role in transportation and overseas moving. A lift van is basically a portable shipping vault. There usually built from wood or reinforced plywood with steel supports or composite materials. Typical sizes varied greatly, but many measured 6 to 8 feet wide, 6 to 8 feet tall and 6 to 12 feet long. These were heavily used for military relocations, office moves, overseas household shipping, and export freight. And honestly, lift vans helped inspire container standardization and showed a need across global shipping. Once businesses realized freight could stay inside one container from start to finish, efficiency exploded.  Now let's move into the giants of global commerce. The ocean shipping containers. These steel boxes changed the world. Before standardized shipping containers, freight was loaded piece by piece onto ships. Imagine loading every box, crate, barrel and pallet by hand. Loading ships could take days. Then standardized containers arrived and global commerce was changed forever.  The 20-foot container became one of the original global standards. There typical dimensions were 20 feet long, 8 feet wide, and 8 feet 6 inches tall with a maximum gross weight of approximately 52,000 pounds, meaning a payload capacity of roughly 47,000 pounds. These containers are commonly used for things like machinery, industrial products, canned goods, and heavy dense freight. And because the container is smaller, it often handles heavy loads better than longer containers.  Now the 24-foot container isn't as common globally, but many domestic and specialized operations use them. You'll sometimes see them in regional transportation arenas, moving operations, specialized freight systems, and certain intermodal applications. They help bridge the gap between maneuverability and increased cube space.   And on to the 40 foot container. The 40-footer became the king of international shipping.  Typical dimensions being 40 feet long, 8 feet wide, 8 feet 6 inches tall with a gross weight of approximately 67,000 pounds. These dominate in retail imports, electronics, furniture, apparel, and consumer goods. When you picture giant stacks of containers on ships, this is usually what you're seeing. And you have the 40 foot and 45 foot high cube containers, both having an extra foot of space. These containers maximize import efficiency, warehouse throughput, transportation cube and trailer equivalent capacity. And anybody that's manually unloaded one during the summer already knows, halfway through that unload, it feels like the container keeps getting longer and longer.  And now let's talk about the refrigerated containers. Or as transportation folks call them reefers. These containers maintain controlled temperatures for frozen foods, produce, pharmaceuticals, dairy, and meat products. And these aren't just cold steel boxes. These are rolling refrigeration systems. They require temperature monitoring, airflow management, fuel systems, maintenance, and constant inspection. One reefer malfunction can destroy an entire load, thousands of dollars in freight, or millions in pharmaceutical products.   Containers certainly improve productivity, but they also introduce risk. We have to respect dock locks, the dock plates, trailer movement devices and chassis, shifting freight and stacking stability.  Ocean containers especially can become dangerous environments. Improperly loaded freight can shift violently when doors open. And overloaded warehouse containers can roll unexpectedly, tip over or create severe ergonomic strain. Sometimes the container itself is the hazard.  From a D container rolling through a grocery warehouse, to a refrigerated 45-foot High Cube crossing the Pacific Ocean, containers help move the entire world. Like we've said many times. every product has a journey. And almost every journey starts with a container. Look around you. Everything you see has probably been on a container, or at least a trailer, and came through a warehouse.   I'm Marty and thanks for listening to another episode of Warehouse and Operations as a Career. Stay productive and never stop learning. Yall stay safe out there. 

General chat and jokes! Graff Letter Game (D), Critiques as per.... Enjoy!Go cop an LDN hat herePlease contribute towards Themes Gofundme hereGet exclusive content over at our Patreon!https://www.patreon.com/armshousepodOur YouTube channel herebuy stuff - INFAMY hereUse Discount code ARMSHOUSE10 for 10% off!(our Patrons get 30% 0ff!)Find EVERY SONG

Join host Graham McMahon, president and CEO of ACCME, as he speaks with registered dietitian Colleen Tewksbury, PhD, MPH, RD, CSOWM, LDN, FAND, incoming Chair of the Commission on Dietetic Registration and Assistant Professor in Nutrition Science at University of Pennsylvania, and pediatrician Christopher Duggan, MD, MPH, Editor in Chief, The American Journal of Clinical Nutrition, and Professor of Nutrition, Harvard University. They discuss evidence-based nutrition care, communicating without stigma, and practical ways interprofessional teams can help patients make sustainable changes amid widespread misinformation. Listen now and share with colleagues who are committed to strengthening nutrition and prevention in everyday practice.

What if one of the most effective tools for brain fog, inflammation, and immune balance isn't a new drug at all, but a repurposed one used in a completely different way? In this episode, Bryana Burken explains how low-dose naltrexone (LDN) works differently at lower doses to support the body's natural healing processes. LDN helps regulate the immune system and has shown benefits for individuals dealing with brain fog, long COVID symptoms, autoimmune conditions, and chronic inflammation. LDN signals the body to produce more of its own natural pain-relieving and mood-balancing compounds, helping improve clarity, energy, and overall function over time. This episode also highlights what to expect when starting LDN, including dosing, timelines for improvement, and how consistency plays a key role in success. While it is not a quick fix, LDN can be a powerful tool when used alongside a comprehensive approach to restoring balance and addressing root causes of health concerns. Watch now and subscribe to our podcasts at www.HotzePodcast.com. To receive a FREE copy of Dr. Hotze's best-selling book, “Hormones, Health, and Happiness,” call 281-698-8698 and mention this podcast. Includes free shipping!

In this episode of Nutrition 411, host Lisa Jones, MA, RDN, LDN, FAND, is joined by Caroline Susie, RDN, LD, to explore the evolving future of dietetics practice. They discuss how emerging forces—including AI, GLP-1 therapies, and the rise of wellness influencers—are reshaping the profession.

In this episode of Nutrition 411, host Lisa Jones, MA, RDN, LDN, FAND, is joined by Caroline Susie, RDN, LD, to explore how dietitians can cut through widespread nutrition misinformation and conflicting messages.

In this episode of Nutrition 411, host Lisa Jones, MA, RDN, LDN, FAND, is joined by Caroline Susie, RDN, LD, to examine how GLP-1 medications are transforming patient expectations in weight management.

In this episode of the Inspire Health Podcast,  Dr. Jen sits down with Erica, a seasoned nurse with 18 years of medical experience and a vital member of the Inspire Health team. Erica isn't just a clinician; she is an advocate for women's health who lived with Crohn's disease for decades. After years of being told her "body was attacking itself" and relying on high-powered biologics, Erica discovered the life-changing intersection of functional medicine, nervous system regulation, and bioidentical support. Dr. Jen and Erica peel back the curtain on what it really looks like to transition from a "chronic patient" to a thriving healer. Erica shares the exact tools—from Low Dose Naltrexone (LDN) to Peptides and Dr. Joe Dispenza's mindset work—that allowed her to walk away from heavy medications and reclaim a life of clarity, energy, and joy. If you've ever felt dismissed by the traditional medical system or feared that your diagnosis was a life sentence, this conversation will remind you that your body is not a mistake—it's a messenger. Themes The "Root Cause" Shift: Moving beyond symptom management to understand why the body is inflamed. The Power of LDN & Peptides: How Low Dose Naltrexone and BPC-157 support autoimmune recovery without the heavy side effects of traditional biologics. Nervous System & Mindset: Why you can't "supplement your way" out of a high-stress state and how meditation changes your biology. Bioidentical Hormones: The missing link in inflammation—how balancing progesterone and estrogen can "move the needle" on gut health. Intuition over Authority: Learning to trust your inner voice when it says there is a better way to heal. Connect with Jen: 

Recently I wrote about research around GLP-1s and nutritional deficiencies. In summary, we looked at a study that showed that most of the clinical trials aren't studying this at all, and that when studies do consider this there are concerning findings, and, finally, the implications of all this.I was recently contacted by a Chicago-area private practice dietitian (MS, RDN, LDN) who had, in fact, written a letter to the editor of the journal that published one of the articles I looked at in Part 2, Malnutrition is Common in Patients Utilizing Glucagon-Like Peptide-1 Agonists Prior to Total Joint Arthroplasty, published in the journal Arthroplasty Today. The letter made important points about the study itself (including the lack of a Registered Dietitian among the authors) as well as issues with the measures chosen and more.This is where I would link to the published letter, except that it's not published. It was rejected, not on the merits of its arguments, but with a single sentence:“We appreciate your letter to the editor but I am not sure that we typically have registered dietician [sic] comment or collaborate on our research." Get full access to Weight and Healthcare at weightandhealthcare.substack.com/subscribe

After turning 60, Deb Benfield began questioning societal messages around aging, vitality, and beauty, and quickly realized how many resources still centered weight loss and youth as ultimate goals. In response, she created what she couldn't find: a framework for nourishing the body that honors inner wisdom, prioritizes quality of life, and embraces the full spectrum of aging.Deb Benfield, M.Ed., RDN, LDN, RYT is a Nutrition Therapist, Registered Dietitian, and Body Image Coach with 40 years of experience helping people heal their relationship with food, movement, and their bodies.In my time with Deb, we discuss her book, Unapologetic Aging: How to Mend and Nourish Your Relationship with Your Body. Specifically, she discusses harmful trends and limiting beliefs regarding ageism, diet and wellness culture, and body shame. She also shares recommendations for caring for our bodies in in this important life stage and reminds us that midlife and beyond holds the opportunity to emerge as your most authentic self.  Buy Melissa L. Johnson's book, Soul-Deep Beauty: Fighting for Our True Worth in a World Demanding Flawless, here. Learn more about Impossible Beauty and join the community here.

Conversation #352:  The Story, Journey and Passion of Cat Rudolph, MS, RD, LDN and Nutritional Sciences PhD StudentToday's conversation is with Cat Rudolph, a registered dietitian and nutritional sciences PhD student. As is a life-long learner, she has taken charge of her future by connecting opportunities challenging her comfort zone to support her professional and personal growth. Her background includes experiences in community nutrition education/research, food security initiatives, farmers' markets, oncology, and clinical nutrition. She is being intentional with her career,  pursuing a doctoral degree in Nutritional Sciences with a minor in public policy at Iowa State University and is excited for what the future holds. Please enjoy my conversation with Cat. Connect with Cat.InstagramLinkedInwww.anneelizabethrd.comCopyright © 2026 AEHC & OPISong: One Of These DaysArtist: The Geminiwww.thegeminimusic.comMusic used by permission. All rights received.© ASCAP OrtmanMusic

Are GLP-1 medications like Ozempic, Wegovy, or Zepbound right for you, especially as an athlete or active adult? And if you are taking one, how do you lose fat without losing muscle?In this episode of Find Your Edge, Coach Chris Newport, RDN, LDN, CISSN, EP shares what she is seeing in practice with patients using GLP-1 medications and explains how to optimize nutrition for better results.You'll learn:how GLP-1 medications workwhy protein is criticalhow to reduce nausea and constipationwhy fiber, hydration, and nutrient density matterwhat athletes need to know about fueling and performancewhy every person on a GLP-1 should work with a registered dietitianWhether you are considering a GLP-1 or already taking one, this episode will help you make more informed decisions.Learn more or work with us here.Experience the breakthrough when everything finally clicks! Train with expert coaches, fuel with incredible chef-prepared meals, and connect with athletes who love triathlon as much as you do. Join us April 22–26 at beautiful Lake Jocassee for four unforgettable days of swim, bike, run, learning, and community. Spots are almost full: Reserve yours here. Support the show

Five events. Eight weeks. Zero excuses.If you're in ops, finance, or senior leadership at an agency or consulting firm – Harv runs through five upcoming events worth getting in your calendar right now.From the Maturity Gap Webinar (where the findings from the business maturity quiz finally get revealed) to the FinOps Conference, two intimate Handbook Breakfast Sessions in London, and – for the first time ever – a Breakfast Session in Manchester.Register as follows:1️⃣ The Maturity Gap Webinar, 15 Apr – https://bit.ly/the-maturity-gap 2️⃣ The Handbook: Breakfast Session 'Multi-Entity Madness', LDN, 23 Apr – https://bit.ly/breakfast-apr263️⃣ The FinOps Conference (50+ headcount businesses), LDN, 21 May – https://bit.ly/finops-conf4️⃣ The Handbook: Breakfast Session 'When Finance Met Ops', LDN, 28 May – Drop Harv a DM on LinkedIn to save you a seat! 5️⃣ The Handbook: Breakfast Session 'When Finance Met Ops', MCR, 3 Jun – Drop Harv a DM on LinkedIn to save you a seat! Hope to see you there! 

Episode 82 of Body Justice Podcast is a follow up conversation with Deb Benfield, a registered dietitian and author of Aging Body Liberation, about the intersection of diet culture and ageism; as well as the covert ways disordered eating is becoming embedded into policy in the U.S. We discuss our thoughts on: ultra-processed foods, seed oils, longevity medication and more.More about Deb:Deb Benfield, M.Ed., RDN, LDN, RYT, is a Registered Dietitian, nutrition therapist, and body image coach with 40 years of experience helping people heal their relationship with food, movement, and their bodies. Her work sits at the intersection of anti-ageism, body liberation, and trauma-informed care, offering a radically compassionate alternative to anti-aging, diet, and wellness culture, especially for those in midlife and beyond.After turning 60, Deb began questioning the dominant narratives around aging, vitality, and beauty—and quickly realized how many resources still centered weight loss and youthful appearance as ultimate goals. In response, she created what she couldn't find: a framework for nourishing the body that honors inner wisdom, prioritizes quality of life, and embraces the full spectrum of aging.She's the author of Unapologetic Aging: How to Mend and Nourish Your Relationship with Your Body and offers individual and group coaching to help others age unapologetically—on their own terms.Disclaimer: this podcast is intended for informational and educational purposes only. This is not a replacement for individual therapy or medical advice. As always, you can find the host of this podcast, Allyson, on her website: ⁠⁠⁠⁠www.eatingdisorderocdtherapy.com⁠⁠⁠⁠ or IG: ⁠⁠⁠⁠@bodyjustice.therapist.⁠⁠⁠Educational resources mentioned:Maintenance Phase- Ultra Processed Foods EpisodesEmily Oster- Seed OilsEmily Oster- Microplastics

In this episode of the Wise Divine Women podcast, Dana Irvine and DANIELLE ARNOLD, MS, CNS, LDN, explore the intricate connections between gut health, hormonal balance, and breast health. They discuss the importance of personalized care through testing, the role of probiotics and digestive enzymes, and the impact of genetics on health outcomes. The conversation emphasizes the need for preventative measures and understanding one's unique health profile to optimize well-being. Danielle is a clinical nutritionist and functional medicine practitioner who supports providers in interpreting functional tests and building microbiome-centered care plans, and she teaches clinical nutrition in an academic setting as well. Together, they are experienced educators who regularly speak with both professional and lay audiences about gut health and the microbiome's role in whole-person care. They can be found online at DesignsforHealth.com.TakeawaysGut health is foundational for overall hormonal balance.Testing is crucial for personalized health care.Probiotics should be tailored to individual needs.Digestive enzymes can significantly improve nutrient absorption.Methylation plays a key role in health and disease prevention.The gallbladder is essential for hormone detoxification.Genetics can inform health strategies but should not be the first step.Lifestyle choices can influence genetic expression.Breast health is closely linked to gut microbiome health.Preventative measures are vital for long-term health.Chapters00:00 Introduction to the Journey of Healing02:53 Understanding Hormonal Health and Its Impact05:36 The Role of Gut Health in Hormonal Balance08:11 Exploring the Connection Between Gut and Breast Health10:51 The Importance of Testing and Personalized Care13:46 Probiotics and Their Role in Gut Health16:40 Digestive Enzymes: A Key to Nutrient Absorption19:11 The Impact of Genetics on Health22:16 Preventive Measures for Breast Health24:47 The Importance of Methylation and Nutrient Absorption27:32 Conclusion and Final ThoughtsIf you're over 40 and feeling:• Tired but wired • Bloated or inflamed • Hormonal and frustrated • Concerned about breast health • Unsure what testing you truly needYou don't need another quick fix. You need clarity.The ⁠Wise Divine Health Clarity Call⁠ is your 1:1 strategy session to uncover root causes and map out your next best steps — whether that's functional testing, thermography, nutrition coaching, or hormone support.

Persistent drool rash can be more than just a messy phase. In this episode, we explore how red, irritated cheeks, especially when they flare at certain times of day, may be early clues that a baby's skin barrier is struggling and that deeper eczema-related issues could be developing.We also unpack how signs like cradle cap, colic, diaper rash, flushing with foods, and mucus in stools can fit into a bigger picture. Tune in to learn how to tell the difference between a drool rash, an eczema flare, and a possible allergic reaction, so you can feel more confident about what your baby's skin may be trying to tell you.My guest, Jennifer Brand, MS, MPH, CNS, LDN, is a clinical nutritionist who helps babies and children with chronic rashes get to the root causes of their skin issues. Known for her pediatric skin-focused approach, she is passionate about helping families support healthy skin through her signature method, Rashes Be Gone.⭐️Mentioned in This Episode:- See all the references

If you have PCOS and feel constantly hungry, deal with strong food cravings, or struggle with binge eating, you are not imagining it. PCOS can directly affect hunger, cravings, and eating patterns through insulin resistance and hormone imbalance. In this episode, Dr. Marianne explains the real link between PCOS and eating disorders so you can understand what is happening in your body without blame. What Is PCOS? PCOS, or polycystic ovary syndrome, is an endocrine and metabolic condition that affects hormones, blood sugar regulation, and appetite. While often labeled as a reproductive issue, PCOS also plays a major role in hunger, food cravings, and disordered eating patterns. PCOS, Insulin Resistance, and Food Cravings Insulin resistance is common in PCOS and can disrupt blood sugar stability. This can lead to increased hunger, intense food cravings, and energy swings throughout the day. These PCOS symptoms are biological and can strongly influence eating behavior, including binge eating. The Link Between PCOS and Eating Disorders The connection between PCOS and eating disorders develops when increased biological hunger meets pressure to restrict food. Restriction can intensify cravings, increase food focus, and contribute to binge eating and disordered eating cycles. This is not a failure of willpower. It is the interaction between hormone imbalance, insulin resistance, and external messaging about food. Neurodivergence, PCOS, and Eating Patterns Neurodivergent individuals may experience additional challenges with eating, including sensory sensitivities, executive functioning differences, and changes in hunger awareness. When combined with PCOS, these factors can make eating feel more complex and require more flexible, individualized support. Why Restriction Can Worsen PCOS and Binge Eating Restricting food can increase hunger and amplify PCOS-related food cravings. This can lead to stronger urges to eat and cycles of binge eating. Supporting consistent nourishment can help stabilize energy, reduce extremes, and support eating disorder recovery. A Non-Restrictive Approach to PCOS and Eating Disorder Recovery Recovery from eating disorders with PCOS requires working with your body, not against it. This includes consistent eating, supporting blood sugar regulation, using low-lift meals, and honoring sensory needs. These approaches can support both hormone balance and a more regulated relationship with food. The Emotional Side of PCOS and Disordered Eating PCOS is often accompanied by body changes and exposure to weight stigma, which can increase distress and drive attempts to control food. Understanding the emotional and social layers of PCOS and eating disorders is an important part of healing. You Are Not Broken If you are living with PCOS, insulin resistance, food cravings, or binge eating, your experience is valid. Your body is responding to real biological processes. Support is possible without restriction, shame, or rigid food rules. Related Episodes Polycystic Ovary Syndrome (PCOS) and Nutrition With Eden Davis, RDN, LDN on Apple & Spotify. Healing Binge Eating Disorder: One Woman's Journey Toward Body Trust & Food Freedom With Dr. Michelle Tubman, M.D. @wayzahealth on Apple & Spotify. Chronic Binge Eating Disorder: Why It Persists & What Real Recovery Looks Like on Apple & Spotify. Work With Dr. Marianne: Binge Eating Recovery Membership If you are struggling with binge eating, disordered eating, or PCOS-related food challenges, Dr. Marianne's binge eating recovery membership offers a non-restrictive, neurodivergent-affirming approach. Learn practical tools to support hunger, reduce food urges, and build a more sustainable relationship with food. Check out more about Dr. Marianne on her website, drmariannemiller.com.

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If you have chronic kidney disease, you've probably been told to cut out potassium, avoid phosphorus-rich foods, and brace for dialysis. But what if most of that advice is outdated and the foods you've been avoiding are actually the ones that could protect your kidneys?In this episode, you'll hear from Jen Hernandez RDN, CSR, LDN, who makes the case that the most powerful thing people with CKD can do isn't eliminate more foods, but stop fearing the ones that were never the problem to begin with.Connect with Destiny:  Instagram / Facebook______________________________

In todays episode, Lindsay Keach Bronstein shares the journey to building a compassionate relationship with our bodies. We explore how tuning into bodily signals, practicing self-care, and shifting societal narratives can foster wellness and resilience, especially during life's transitions, illness and menopause for designing a life we can live inside of.   Key Topics: Building a compassionate relationship with the body Listening to bodily signals and intuition Shifting societal narratives around women's health   FOLLOW LINDSAY:  Join her on Substack: https://bodypartnership.substack.com/ Lindsays Website: https://feedhealth.com/     Follow Lisa: LinkedIn: https://www.linkedin.com/in/lisamalianorman/ Instagram: https://www.instagram.com/lisamalia.evoke/ Join The Feminine Leadership Lounge: https://circle.lisamalia.co/join   Lindsay Keach Bronstein (MS, RDN, LDN, HC) is an integrative dietitian and health coach who has spent nearly two decades helping people transform their relationship with their bodies from projects to fix into caring, collaborative partnerships. After her own diagnosis with Crohn's disease in her early twenties, Lindsay learned firsthand that healing isn't just about treating symptoms. It requires a completely different relationship with your body: one built on care and curiosity rather than control. That journey became the foundation of the Body Partnership Method.  Lindsay's work lives at the intersection of science and soul. She brings deep clinical expertise, shaped by years of clinical work and teaching at one of the country's leading integrative medicine centers, alongside a profound respect for the body wisdom and intuition that no textbook can fully capture. She helps people weave both together: using evidence and their own body's signals to discover what is actually true for them, in this body, in this season of life.   She works with people navigating digestive challenges, migraines, hormonal shifts, and complex chronic conditions, always through the lens of curiosity, collaboration, and compassion rather than control. Lindsay has a virtual practice based in Massachusetts and publishes The Body Partnership on Substack.   CHAPTERS:  00:00 Introduction to Body Partnership and Healing 02:06 Lindsay's Journey: From Designer to Health Coach 07:37 The Body as the Last Frontier for Women 13:11 Integrating Science and Intuition in Wellness 18:51 Understanding Supplement Efficacy 21:51 The Journey of Self-Acceptance and Change 25:33 The Importance of Self-Care in Today's World 29:01 Building a Relationship with Your Body 31:18 Practical Steps for Body Partnership

Episode 81 of Body Justice Podcast is all about the intersection of diet culture and ageism. We discuss how these systems impact our relationship to food and body, especially as we age. We explore how the skincare industry has emerged as the new diet culture and how it is rooted in a socialized fear of aging. Deb shares her own lived experience as a woman in her late 60s, a professional in the eating disorder field with decades of experience- and how she aims to challenge these harmful systems in her work with clients and anyone who follows her work.More about Deb:Deb Benfield, M.Ed., RDN, LDN, RYT, is a Registered Dietitian, nutrition therapist, and body image coach with 40 years of experience helping people heal their relationship with food, movement, and their bodies. Her work sits at the intersection of anti-ageism, body liberation, and trauma-informed care, offering a radically compassionate alternative to anti-aging, diet, and wellness culture, especially for those in midlife and beyond.After turning 60, Deb began questioning the dominant narratives around aging, vitality, and beauty—and quickly realized how many resources still centered weight loss and youthful appearance as ultimate goals. In response, she created what she couldn't find: a framework for nourishing the body that honors inner wisdom, prioritizes quality of life, and embraces the full spectrum of aging.She's the author of Unapologetic Aging: How to Mend and Nourish Your Relationship with Your Body and offers individual and group coaching to help others age unapologetically—on their own terms.Disclaimer: this podcast is intended for informational and educational purposes only. This is not a replacement for individual therapy or medical advice. As always, you can find the host of this podcast, Allyson, on her website: ⁠⁠⁠www.eatingdisorderocdtherapy.com⁠⁠⁠ or IG: ⁠⁠⁠@bodyjustice.therapist.⁠⁠⁠

What if your low energy or stubborn performance plateau have little to do with your training, and everything to do with your thyroid?In episode 133 of The Eat for Endurance Podcast, I'm joined by Katie Morra, MS, RD, LDN, IFMCP, to talk all about thyroid health for athletes. Katie is a Registered Dietitian and former Division 1 athlete who specializes in complex chronic illness. Her practice, Gut Honest Truth, focuses on the identification and treatment of root causes behind chronic inflammatory conditions, autoimmune disease, gastrointestinal dysfunction, and thyroid dysfunction.In this episode, Katie and I discuss:What the thyroid actually does and how it impacts almost everything in the bodyCommon signs of thyroid dysfunction in active peopleThe connection between underfueling, stress, and thyroid functionWhy looking at TSH alone doesn't tell the full story, and what you should get tested insteadKey nutrients for thyroid health How gut health impacts nutrient absorption and thyroid functionWhen someone may need thyroid medicationThe difference between Hashimoto's and hypothyroidism caused by underfuelingPractical nutrition and lifestyle strategies to support the thyroidThis is a complex topic and we only scratch the surface, but it's a really helpful starting point if you've ever wondered whether your thyroid could be playing a role in how you feel or perform.

If you have ever felt overwhelmed trying to help your child with eating, weight, or health—this conversation is for you.In this episode of Family in Focus, I'm joined by Joey Skelton, MD, MS, FAAP and Dara Garner-Edwards, MSW, LCSW, co-authors of Your Child Is Not Their Weight: Parenting in a Size-Obsessed World.Together, we explore how to support your child without shame, pressure, or food battles—and why focusing on weight often does more harm than good.Dr. Skelton and Dara bring nearly two decades of experience working with families through the Brenner FIT Program at Wake Forest University, where they focus on practical, family-centered care that creates lasting change.In this episode, we discuss:• Why weight-focused conversations can backfire• What children actually hear when we talk about food• The impact of pressure, restriction, and “fixing”• How to support your child's health without shame• Why connection—not control—creates real change• The power of family meals and reducing stressIf you've ever felt stuck or unsure how to help your child, this episode offers a new way forward.About Our GuestsJoey Skelton, MD, MS, FAAP – Pediatrician and professor at Wake Forest University School of Medicine, leading the Brenner FIT Program.Dara Garner-Edwards, MSW, LCSW – Family counselor specializing in helping families create sustainable change without shame or judgment.Along with Melissa Moses, MS, RDN, LDN (co-author and registered dietitian), they wrote:

On today's episode of The Wholesome Fertility Podcast, Michelle sits down with Aimee Raupp (@aimeeraupp) to explore the latest breakthroughs in fertility science and ovarian rejuvenation. From PRP (platelet-rich plasma) therapy and rapamycin to senolytics, peptides, and low-dose naltrexone (LDN), this conversation dives into emerging tools that may support egg quality, ovarian function, and fertility after 35. They also challenge long-standing scientific dogma around ovarian aging and discuss whether women are truly born with all the eggs they'll ever have. If you're navigating diminished ovarian reserve, PCOS, endometriosis, insulin resistance, or age-related fertility concerns, this episode offers cutting-edge insights and practical hope grounded in evolving research. Key Takeaways: PRP ovarian rejuvenation may improve ovarian function and support natural conception in some women. Emerging research questions the belief that women are born with all their eggs, opening new conversations about ovarian aging and regeneration. Rapamycin and senolytics (like fisetin) are being studied for their potential role in delaying ovarian aging and reducing inflammation. Peptide therapy may support hormonal balance, egg quality, insulin sensitivity, and conditions like PCOS. Low Dose Naltrexone (LDN) may help regulate immune function, reduce inflammation, and support fertility outcomes in certain cases. Guest Bio: Aimee Raupp (@aimeeraupp) , MS, LAc, is a leading fertility expert, licensed acupuncturist, women's health advocate, and bestselling author dedicated to helping women improve egg quality, balance hormones, and optimize their ability to get and stay pregnant, naturally or with IVF. She is the author of Chill Out & Get Healthy, Yes, You Can Get Pregnant, Body Belief, and The Egg Quality Diet, a clinically proven 100-day fertility program designed to reduce inflammation and enhance reproductive health. With over 20 years of clinical experience, Aimee works with clients worldwide through virtual fertility coaching and treats patients at her New York and Connecticut clinics. She is the founder of Aimee Raupp Beauty and co-founder of Rejoova, a science-backed fertility supplement company supporting egg and sperm health. Her work has been featured on The View and in Glamour, Allure, Shape, Well + Good, MindBodyGreen, and GOOP, with endorsements from leaders in wellness and personal development. Connect with Aimee Raupp: Visit her websiteFollow her on Instagram Follow her on Tiktok Learn more Healthgevity here For more information on working with Aimee and her team of fertility coaches and acupuncturists, email info@aimeeraupp.com Disclaimer: The information shared on this podcast is for educational and informational purposes only and is not intended as medical advice. Please consult with your healthcare provider before making any changes to your health or fertility care. Ready to discover what your body needs most on your fertility journey? Take the personalized quiz inside The Wholesome Fertility Journey and get tailored resources to meet you exactly where you are:  https://www.michelleoravitz.com/the-wholesome-fertility-journey For more about my work and offerings, visit: www.michelleoravitz.com Curious about ancient wisdom for fertility? Grab my book The Way of Fertility: https://www.michelleoravitz.com/thewayoffertility Join the Wholesome Fertility Facebook Group for free resources & community support: https://www.facebook.com/groups/2149554308396504/ Connect with me on social: Instagram: @thewholesomelotusfertilityFacebook: The Wholesome Lotus  

In this Q&A episode, Dr. Eric answers listener-submitted questions all about thyroid antibodies—what they are, why they matter, and how they impact both Graves' disease and Hashimoto's thyroiditis. He begins by clarifying the three main thyroid antibodies—TPO, TSI/TRAB, and thyroglobulin antibodies—and explains why understanding these markers is critical when assessing true remission.Throughout the episode, Dr. Eric addresses common concerns such as: Can you be in remission if antibodies are still positive? How often should antibodies be tested? Can diet alone normalize them? He also explores the role of environmental triggers, gut health, gluten, iodine, and even supplements like selenium, black seed oil, and low-dose naltrexone (LDN). You'll hear practical guidance on why antibodies fluctuate, what “optimal” really means (not just “within range”), and why many conventional endocrinologists don't routinely monitor these markers.If you're confused about your antibody results—or wondering why you relapsed after being told you were “in remission”—this episode will help you connect the dots. If you want a clearer, more balanced understanding of thyroid antibodies and what they really mean for your recovery, you'll get a lot out of this episode.If you want to subscribe to my free Healing Graves' Naturally newsletter visithttps://savemythyroid.com/GravesNewsletter Free resources for your thyroid healthGet your FREE Thyroid and Immune Health Restoration Action Points Checklist at SaveMyThyroidChecklist.comHigh-Quality Nutritional Supplements For Hyperthyroidism and Hashimoto' s Have you checked out my new ThyroSave supplement line? These high-quality supplements can benefit those with hyperthyroidism and Hashimoto's, and you can receive special offers, along with 10% off your first order, by signing up for emails and text messages when you visit ThyroSave.com. Do You Want Help Saving Your Thyroid?Get free access to hundreds of articles and blog posts: https://www.naturalendocrinesolutions.com/articles/all-other-articles Watch Dr. Eric's YouTube channel: https://www.youtube.com/c/NaturalThyroidDoctor/videos Join Dr. Eric's Graves' disease and Hashimoto's group: https://www.facebook.com/groups/saveyourthyroid Take the Thyroid Saving Score Quiz: https://quiz.savemythyroidquiz.com/sf/237dc308 Read all of Dr. Eric's published books: http://savemythyroid.com/thyroidbooks Work with Dr. Eric: https://savemythyroid.com/work-with-dr-eric/

What if the reason you’re not healing isn’t that you need another diagnosis? 0:08 It’s that your cells aren’t receiving the right signals. Because the body doesn’t run on diagnosis, it runs on 0:16 communication. And peptides are one of the most powerful, most misunderstood 0:21 tools we have for cellular signaling, immune balance, tissue repair, gut 0:27 lining support, metabolic control, brain signaling, sleep cycles, and even sexual 0:35 wellness. Today, I’m going to do what most people won’t. Define peptides in 0:41 plain English for you. break them into categories by what they’re best at and 0:47 tell you which ones are FDA approved on the list and which ones are commonly 0:53 used off label or investigational with the evidence that actually says these 1:00 work. This is going to be a powerful episode and if you’ve ever felt like you’re hearing hype without clarity, 1:07 this one’s for you. So, as usual, grab your cup of coffee or tea and settle in 1:13 as we talk about peptides that can fit into your healing journey. We’re going 1:19 to have a short word from our sponsor. You know, we got to do that. That’s how we stay on the air here. So, we will be 1:26 right back after this. Did you know sweating can literally heal your cells? 1:32I nfrared saunas don’t just relax you. They detox your body, balance hormones, 1:37 and boost mitochondrial energy. I’m obsessed with my health tech sauna. And 1:42 right now, you can save $500 with my code at healthtechalth.com/drmuthqen25. 1:54 All right, here we go, guys. I am excited to dive into peptides with you. 2:00 So understanding peptides is foundational, right? And I’ve been 2:06 studying peptides now for about nine years. Um, and I find that they are 2:13 incredible. Um, so I want to break down for you what peptides actually are, what 2:19 they do, and some of the top peptides that are available today, and how they 2:25 can be utilized. Because I think it’s really important. And I think it’s it’s there’s a lot of confusion out there about what these things actually are and 2:32 are they safe? Are they not? When do we use them? What’s the science behind them? So, we’re going to dive in and 2:38 we’re going to talk about all things peptides. So, let’s get ready here. Here we go. So, peptides are short chains of 2:45 amino acids and they typically range anywhere from 2 to 50 amino acids and 2:51 they’re linked by peptide bonds. So think of them as the superglue that holds the amino acids together. They sit 2:58 between the amino acids and they are full proteins in terms of their size and 3:04 their complex structure. And what makes peptides particularly interesting in 3:10 medicine is their role as signaling molecules. They’re essentially the 3:15 body’s text messages carrying specific instructions to cells and tissues. And 3:21 unlike our proteins which often serve as structural roles or act as enzymes, 3:28 peptides typically function as hormones, neurotransmitters and growth factors and 3:33 they bind to specific receptors on the cell’s surfaces or within the cells and 3:39 they trigger this effect. It’s like a cascade effect of a biochemical reaction 3:45 that ultimately changes the cellular behavior. So basically, it’s changing 3:50 the way the body’s cell structure acts. And this is why peptides can be so 3:56 incredibly powerful and therapeutic when you introduce the right peptide signal. 4:02 Now, you could theoretically redirect cellular processes toward healing, 4:07 towards metabolism, immune balance, tissue repair. Any of those things can 4:14 be manipulated to do a certain thing once we add the peptide. The challenge 4:19 in peptide medicine though lies in distinguishing between those peptides that have been rigorously studied, 4:26 proven safe and effective and approved by regulatory bodies like the FDA versus 4:31 those that exist in what we call the gray zone of a promising clinical data. 4:36 But they really lack human validation so far. And this distinction is critical because the presence of a plausible 4:43 mechanism does not guarantee safety or efficacy in living humans. So, this is 4:50 really important and we’re going to dive in and look at some of the research on all of these different peptides that are 4:56 available and I’m excited to say there’s some amazing peptides being studied right now that unfortunately are not 5:01 available. But I can’t wait to see them hit the market for us because it is going to be a gamecher as far as health 5:09 and longevity. So there is a quality control issue and there is a hidden 5:14 variable in peptide medicine with this and it’s one of the most underappreciated aspects of peptide 5:21 therapy particularly for non-FDA approved peptides. It’s quality control. 5:26 When we discuss pharmaceutical medicines, we take for granted that the pill contains what the label says. Not 5:32 always true depending on where it comes from. You guys, if you’ve heard my episodes before talk about how many of our medications are made in China and 5:41 have been contaminated with other things, you will realize that that is not always true. So, just because it has 5:48 the FDA stamp of approval on the medication, it still does not necessarily mean it’s safe and we still 5:54 need to do our homework on it. So, sorry for digressing on you guys, but you know, when we get a medication, we we 6:00 think that what the amount says is what is there, doesn’t have contaminants, it’s manufactured with good 6:06 manufacturing practices. You’ll see that listed as GMP on the bottle, and it’s been stored properly, it’s been 6:12 maintained stable, and with research peptides and compounded formulations, 6:17 none of this can be assumed. So, I will share a story with you. There was a gentleman that was purchasing these 6:24 peptides online from a research facility and um did not know that they were 6:30 coming from China and he was ordering a particular growth hormone peptide and 6:35 after a little while he had he had done fine for the few first few bottles. After a little while he started having 6:42 some complications. He started getting really irritable and angry and ragy and 6:47 he didn’t quite know what was going on. And so he decided to go get some testing done. He had some blood testing done and 6:53 his testosterone level was over 5,000. So for those of you who know what testosterone level should be for a guy, 7:00 they really shouldn’t be any higher than about 1,00200 would be absolute max that we’d want to see. Now he was taking 7:06 testosterone but not to that degree. And prior to adding this peptide, his 7:12 testosterone was very stable. What they ended up finding out was the peptide that he was getting, whoever was 7:18 manufacturing it added testosterone to the peptide. They felt like if if it had growth hormone, that was great, but if 7:25 it had growth hormone and tes testosterone, all the better. And he didn’t know that. And this is the 7:31 problem that we can have with peptides if you don’t source them properly. if you’re not working with somebody that 7:37 knows how to source them and can prove that they are what they say they are. Um, I’m sure there’s a whole bunch of 7:42 studies out there too of people getting these peptides and paying hundreds of thousands of dollars for them over their 7:48 lifetime and finding out they were nothing more than just sterile water. So, you really do need to be careful 7:53 with your quality control. Now, this kind of leads us right into the next topic that we’re going to talk about and that’s the manufacturing question, 8:00 right? The FDA approved peptides are manufactured in facilities subject to 8:05 the FDA inspection rules following our GMP regulations and these facilities 8:11 must validate their manufacturing process, demonstrate consistency batch to batch, test for purity and potency. 8:18 They need to test for bacterial endotoxins and sterility and they need to maintain detailed records. So, when a 8:25 pharmaceutical company submits a drug application, the FDA inspects the manufacturing facility as part of the 8:32 approval process. If you’re getting peptides from a different country, none of that is happening. And there are some 8:38 ways for us to determine if that is what you’re getting. Typically, the rule of thumb is if your peptides are coming 8:44 with a different colored top, every one of them has a different colored top. Those are typically being sourced out of 8:49 China. I wouldn’t say that’s 100% but that’s kind of the rule of thumb that people follow. So compoundingies these 8:56 are thearmacies that make our bio identical hormones. They can make medications in any dose or strength or 9:02 route. There are thousands of them in every not that not in every state but 9:08 there are thousands of them around the country right now. So these compoundingies are registered as 503A 9:15 facilities. They do traditional compounding for individual prescriptions, right? Like they can make 9:20 thyroid, they can make LDN, they can make estrogen. You can also have a 503b 9:27 facility, which is an outsourcing facility. And these companies produce larger batches of products. They’re they 9:34 have some oversight, but they’re less stringent than for FDA approved 9:40 manufacturers. And state boards of pharmacy regulate a 503A pharmacy. And 9:45 the FDA can inspect the 503b facility, but doesn’t preapprove any of their 9:52 compounding products. So, they can inspect it, but they don’t approve them. So, research chemicals and these 9:58 suppliers operate essentially with no oversight. They explicitly market products for research use only, not for 10:06 human consumption to avoid FDA regulation. If they put that on their 10:12 product, they don’t have to comply to what the FDA is saying. And there is no required manufacturing strategies or 10:19 standards, no required testing, no required sterility assurance, and no enforcement mechanisms if products are 10:26 mislabeled or contaminated. So basically, they don’t have the liability, but that doesn’t mean that 10:31 all of them are badies or bad suppliers. It just means they don’t have to comply 10:37 to the FDA rules. Now, there are many of these companies that I’ve seen and I’ve talked to that do do a lot of this. They 10:44 do test their product for sterility. They do test their product to make sure it is what it says it is. They don’t 10:51 have to, but they do. So, if you’re going to decide to use a company that 10:56 has research only, not for human consumption, at least ask for their 11:02 proof of testing so that you know that the product you’re getting is what it says it is and that it’s clean. Because 11:08 this is where we run into the problem is in purity. So in purity peptide 11:13 synthesis can produce not just the targeted peptide but also related 11:19 peptides with deletions, substitutions, truncations or truncations of amino 11:25 acids. Sorry. And this high performance liquid we call it uh chromatography can 11:30 separate these related impurities and quality and quantify the actual target 11:35 of the peptide content. So a certificate of analysis is what you want to ask these companies for. This shows the HPLC 11:44 the testing mechanism with greater than 95% or ideally 98% purity which 11:51 indicates a higher quality product. So this certificate of analysis can be fabricated may not represent the 11:57 specific batch being sold. It happens. We need to know not everybody is honest. Not everybody, you know, does what they 12:03 say and it does what’s right. But at least you at least they’re giving you something and you have some security. 12:10 and then choose a company that was referred to by someone else that has done some homework as well. In in 12:16 commercial research, there’s independent testing and they research peptides and this has been really shocking 12:23 variability that they’ve seen. Some products contain 50% or less of the 12:29 claimed peptide and some contained primarily degradation of the product or manufacturing impurities and some 12:36 contained bacterial endotoxins at levels that could cause fever and systemic 12:42 inflammation if it was truly injected. And I would also worry with some of those problems, you know, depending on 12:48 what impurity or bacterial endotoxin was there. If you’re using a product to boost your immune system and your immune 12:54 system is already compromised, these bacterial endotoxins can actually make you sicker instead of what you want it 13:02 to do, which is making you better. So, sterility is always an issue with anything that is manufactured, 13:08 especially things that we’re doing as an injection. Peptides are intended for injection. They must be sterile. They 13:16 must be kept safe. And pharmaceutical manufacturers conduct this sterility testing on every batch. 13:22 Compoundingarmacies should conduct sterility testing particularly for high-risisk compounded 13:28 sterile preparations and research chemical suppliers may or may not conduct any testing. So injecting 13:35 non-sterile material can cause local infections, abscesses at the injection 13:41 site and or if the bacteria enters the bloodstream could potentially be 13:46 life-threatening and you could have sepsis. Now, excuse me. We saw this 13:52 happen in a compounding pharmacy uh gosh, it’s probably been 10 years ago 13:57 now, I think. um they unfortunately had a strep uh contamination in their 14:03 product and they weren’t testing it. It was a large compounding pharmacy out of Florida and they were making products 14:08 that were being injected into the joints and um these people got very very sick 14:14 and some of them died and um some of them got very very injured by this uh 14:21 complication that happened. So it’s not like this doesn’t happen. It does, but it doesn’t happen often. And that’s what 14:28 we have to know about. And so, when we’re talking with you guys about storage and stability, it’s really 14:34 important to make sure you maintain your peptides well. So, many peptides are unstable at room temperature. They 14:41 require refrigeration or freezing. We tell everyone to make sure you’re refrigerating your peptides. That way, 14:48 there’s no question about it. when it stays cold um it prevents or slows down 14:54 the process of uh bacteria growing in it. So some of these peptides actually 14:59 degrade very rapidly in the solution and they must be reconstituted immediately before use and reconstitution of the 15:07 peptides really has limited stability often just days to weeks not months. So 15:13 improper storage, temperature, um changes during shipping or prolonged 15:19 storage of a reconstituted product can lead to degradation into inactivity or 15:25 potentially even a harmful breakdown of the product itself. So if you have a product that’s been sitting in your 15:30 refrigerator for a month or two months or 3 months or 6 months, just throw it away. It’s not going to be any good. 15:37 you’re not going to actually get the peptide and the uh potency that you’re looking for anyway out of it and the 15:44 potential of you introducing an endotoxin, a bacterial endotoxin is quite high at that point. So you just 15:50 really don’t want to take the risk, excuse me. So what practitioners, what 15:56 should we do and what should patients do? Well, for any peptide therapy, we 16:03 want to source our verification. know where the peptide product comes from. Is 16:08 it an FDA approved product? Is it a 503b compounding? A research chemical 16:14 supplier? Is there a certificate of analysis? Request and review this COA. 16:20 And you want it to show purity greater than 95% but ideally greater than 98%. 16:27 You want that identity be identity to be confirmed by mass spectromedy. Uh 16:33 sterility testing should be done. Bacterial endotoxin testing should be done. Batch number matching of the 16:39 product that you received should be done. Proper storage. You want to know that this has been refrigerated or 16:46 frozen as directed once it’s been mixed. Look at the expiration dates for reconstituting your peptides. Track that 16:53 reconstitution date and discarded accordingly like we just talked about. Monitor for your adverse effects. Even 17:01 with the perfect quality control, monitoring for adverse effects is essential with questionable quality and 17:08 vigilance is really critical here. I know it’s frustrating for a lot of patients when they have to get several 17:15 bottles and they only last a week or two. right here, you guys. This is why 17:21 they only last a short period of time because once they’re mixed, they start 17:26 to degrade and they won’t be good and you won’t get the benefit from it. So, 17:31 it’s really important with these research peptides specifically, practitioners should recognize that all 17:38 recommending products without quality assurance violates the fundamental medical principle of first do no harm. 17:45 If a patient is determined to use research peptides despite counseling, providing guidance on quality 17:52 verification, requesting those COAs, using pharmaceutical grade sources when available, proper testing, this all 17:59 reduces harm, but doesn’t constitute necessarily that recommendation. Now, 18:06 that being said, today it’s very difficult to find peptides by the compoundingies because of what the FDA 18:13 has done. So most of the peptides that are available to us have been labeled 18:18 not for human consumption, not because they’re not good products, but because 18:25 of what the FDA did. And this is how these companies have been able to 18:31 continue to provide peptides to the medical community. And if you know you 18:36 have a good company, then you’re, you know, you’re still taking the risk, right? But at the end of the day, the 18:42 reason they’re doing that is to protect themselves from the FDA, from liability. Um, so just kind of know that there is 18:50 some talk in the community with um Bobby Kennedy that this is going to change and 18:55 they are going to bring peptides back to the compounding pharmacies. Now, we don’t know which ones they’re going to 19:01 bring back. Uh, will it be all of them? Will it just be some of them? What’s going to happen here? Um, is it going to 19:07 go to the pharmaceutical companies like our GLP1s did? We don’t know what that’s going to look like quite yet. Um, but it 19:14 is coming and that is positive news. So, let’s talk now about FDA approved 19:21 peptide medications. So, this is the metabolic revolution, right? GLP1 19:28 and our dual increeting agonists. This is an exciting time. GLP-1s are amazing. 19:35 Um, a lot of people are skeptical, a lot of people love them, a lot of people hate them. Whichever side of the fence 19:42 that you’re on, I understand. But I want to talk about the science of it today 19:48 and what it actually means for people. So, the story of GLP1 glucagon like 19:54 peptide one represents one of the most significant advances in metabolic 19:59 medicine in the past several decades. GLP-1 is an accretin hormone. It’s 20:05 gutder derived peptide that potentiates insulin secretion in response to food 20:11 intake. And the body naturally produces GLP-1 in the intestinal L cells, but it 20:17 rapidly degraded by the enzyme DPP4 giving it a halflife of only about 2 20:24 minutes. So this rapid breakdown made in therapeutically impractical until 20:31 research was developed and modified the analoges that resist the enzyme degradation. So for those people who 20:39 never feel full when they’re eating, never feel satisfied when they’re done, this is because their body is either not 20:46 producing enough GLP1 or it’s not getting the signal right. And this is a 20:51 leptin issue. This is an insulin issue. It’s a GLP-1 issue. It’s a complicated 20:56 issue. This is not anything that the person is doing wrong. It’s what is happening to their body. And so GLP1s 21:03 have really revolutionized this. So one particular GLP-1 that we have is 21:09 semiglutide. And this GLP-1 agonist is what changed everything in the world of 21:16 metabolic medicine. Semiglutide is marketed as ompic for type 2 diabetes 21:23 and it’s marketed as WGOI for chronic weight management. It is a modified 21:29 GLP-1 analog with 95 or sorry 94% amino acid sequence uh homology to human 21:37 GLP-1. So it means that it’s it’s just like our own GLP-1 that we make. This 21:42 modification includes specific amino acid substitutions and the addition of C18 21:50 a fatty acid chain which allows the peptide to bind to albumin. Now this 21:56 albumin binding dramatically extends the half-life to approximately one week 22:01 enabling one weekly dosing which is a major advantage over the earlier GLP-1 22:07 agonists that require daily or twice daily injections. The mechanism by which 22:13 semiglutide works is multiaceted. At the pancreatin level, it binds to GLP-1 22:20 receptors on the pancreatic beta cells enhancing glucose depending sorry 22:27 enhancing glucose dependent insulin secretion. This glucose dependency is 22:33 crucial. It means the peptide only stimulates insulin release when blood glucose is elevated. This dramatically 22:41 reduces the hypoglycemic risk compared to insulin or even uh sulfuras. 22:47 Simultaneously semiglutide suppresses glucagon secretion from pancreatic alpha 22:53 cells further improving glycemic control. This is really amazing because 23:00 over the years when we’ve used insulin, which is also a peptide by the way, you 23:05 had to dose it just right because if you didn’t, you would produce so much insulin that it would crash the blood 23:12 sugar and then somebody would have too low of a blood sugar. They’d be hypoglycemic and they’d have to eat more 23:18 sugar and then they’d have to modify the insulin again and the person would be going up and down, up and down, up and 23:24 down all day long. And that created a lot of problems for people and so this 23:30 helps to stabilize that so it is not such an intense change. Now in the GI 23:36 tract semiglutide delays the gastric emptying particularly pronounced during 23:41 the initial weeks of therapy. This slowing of the gastric emptying contributes to the sensation of being 23:48 full and early satiety that patients often describe. However, this effect 23:54 tends to attend to weight over time as the body adapts through the appetite 24:00 suppressing effects generally persist through central mechanisms. So, when we 24:05 talk about what is actually happening, we’re slowing that digestive process down. That’s why people aren’t so 24:11 hungry. It’s why they’re not eating so much. This is why people can develop constipation with these products because 24:17 it’s slowing the body’s digestive tract down. Now some people will call this 24:22 gastroparesis. Um gastroparesis is actually different. 24:28 It is when we lose control over what’s happening in the in the colon like the 24:34 nerves and things like that just stop working. I have never seen that with the GLP1s that we prescribe in micro doing. 24:42 um it’s been documented. It can happen, but again it a lot of it is dosing and a 24:48 lot of it is staying on top of your client and what’s happening and what’s going on and what you’re doing and making sure that they do have good 24:54 motility still. So a lot of these things can be mitigated if you have problems 24:59 with them. Now one of the most profound effects of semiglutide occur in the 25:05 central nervous system. GLP-1 receptors are widely distributed in the brain 25:10 particularly in the hypothalamus and the brain stem area where we are involved in 25:15 appetite regulation. So when when wilding and colleagues published their 25:20 landmark step one trial in the New England Journal of Medicine in 2021, 25:25 they demonstrated that participants receiving 2.4 4 milligrams of semiglutide weekly achieved an average 25:32 weight loss of 14.9% of their body weight over 68 weeks. Now, I want you 25:39 guys to really understand this. We’re talking roughly 15% body weight loss 25:45 over a year, longer than a year. 52 weeks is a year, right? This is 68 25:50 weeks. So, it took longer for them to lose. We’re not talking about giving 25:55 somebody a dose to lose 15% of their body mass in a month or two. That that 26:01 is not healthy for any of us. That is not what we’re talking about doing here. Now, they compared this to placebo and 26:08 the placebo was only 2.4%. So, that is a significant difference. 26:14 And even beyond the numbers, patients reported something very qualitatively different, a reduction in what’s now 26:21 called food noise. Everybody knows what food noise is. We’ve talked about this long before GLP1. It’s that craving. 26:28 It’s that part of your brain that just keeps thinking about I want to eat something. You know, that was actually 26:34 reduced and they didn’t expect to see that happen. Now, this refers to the constant mental preoccupation with food, 26:42 the intrusive thoughts about eating, the difficulty in feeling satisfied. Semi-glutide appears to appears to 26:49 modulate reward pathways in the misolyic system reducing hedonic eating and food 26:57 cravings. Now there are also great cardiovascular effects of semiglutide 27:02 that extend beyond weight loss. Uh the sustained six and select trials 27:07 demonstrated significant reductions in major adverse cardiovascular events uh 27:14 mace in high-risisk populations. The select trial published in 2023 showed 27:20 that semiglutide reduced cardiovascular death, non-fatal myioardial inffection 27:25 and non-fatal stroke by 20% in adults with overweight or obesity and 27:31 established cardiovascular disease but without diabetes. So this suggests that 27:37 mechanisms beyond glucose control and weight loss possibly including 27:42 anti-inflammatory effects, improvements in endothelial function and favorable 27:47 changes to lipid profiles. Now I will tell you the clients that I work with that are on GLP1, 27:53 they will tell you that their inflammation has been significantly reduced. We are also seeing really 28:00 amazing results in lipid profiles. um part of its weight loss, but there is a 28:06 component to this that is lowering the triglyceride levels because it’s related to sugar and how the body’s processing 28:11 it. And we’re seeing better profiles, less need for statins as a result of 28:17 that. If if you want to listen to my episode on statins, I have one on that. Uh they are not my favorite medication. 28:24 I think it’s overprescribed and overused um and not really affecting or 28:29 addressing the problem. So these things can really be helpful. There’s also some 28:34 uh ramblings going on with GLP-1s saying that they may be able to help with 28:40 addiction in the future because of where they’re finding it affecting the brain and how it affects the food noise and 28:47 the cravings that we have for food and the addiction for food. Could it potentially help with other addictions 28:53 down the road? We’ll have to wait and see on that one. So semiglutide’s FDA prescribing information also includes a 29:00 box uh boxed warning about thyroid sea cell tumors. So in rodent studies 29:06 semiglutide caused dose dependent and treatment duration dependent sea cell 29:12 tumors at clinically relevant exposures. So while it’s unknown whether or not 29:17 semiglutide causes uh thyroid cancer tumors in humans and the rodent thyroid biology 29:26 differs significantly from humans, the drug is contraindicated in patients with a personal or family history of 29:33 medillary thyroid carcinoma or in patients with multiple endocrine neopl neoplasia syndrome type two. it is 29:42 uh contraindicated for safety effects with that. Um I have seen endocrinologists okay GLP1s to be used 29:50 in patients who’ve had other forms of thyroid cancer just not the meillary 29:55 thyroid cancer. So there is possibility there. Now the most common side effects 30:00 are gastrointestinal. It’s nausea affects about 20 to 44% of patients 30:06 depending on the formulation with diarrhea, vomiting, constipation, abdominal pain, and also frequently 30:13 reported in clinical trials. I see this in my clinic, too, especially dose dependent. Um, and it happens early on 30:20 when you’re first starting the medication, but seems to settle out over time. The one that I would add to this 30:26 that I don’t think they have on here is an increase in acid reflux. We also see that quite often uh especially in people 30:33 who suffer with acid reflux to begin with. Now these effects are typically most 30:40 pronounced during the escalation and they like I said often improve over time 30:45 but more serious but less common adverse effects include acute pancreatitis. 30:51 The medication needs to be discontinued immediately if this is confirmed. You can see some diabetic retinopathy 30:57 complications in patients with pre-existing retinopathy and acute kidney injury. Um, this usually happens 31:05 secondarily to dehydration from the GI effects. There are some gallbladder disease um that can occur and people who 31:13 have a sensitive gallbladder will describe uh discomfort with that. I’ve 31:18 even seen some people who’ve had their gallbladder out on GLP1s at the higher doses complain of similar pain that they 31:25 used to have when their gallbladder was in. So, really important to just kind of monitor these symptoms and work closely 31:32 with somebody that understands them and can be on top of them quite quickly if this happens. Excuse me. From an 31:39 integrative medicine perspective, semiglutide really represents a powerful tool, but it’s not a standalone 31:46 solution. Remember, the medication addresses one aspect of the metabolic dysfunction, the signaling systems 31:53 controlling appetite and glucose homeostasis, but it doesn’t address the root cause that led to the metabolic 32:00 disease in the first place. Patients who rely solely on the medication without addressing the ultrarocessed food 32:07 consumption, the ccadian disruptions, the chronic stress, the sleep apnea, or 32:12 underlying hormonal imbalances often experience weight regain when the medication is discontinued. 32:20 The drug is also not a substitute for addressing the emotional and psychological drivers of eating 32:26 behavior, including the unresolved trauma that may manifest as emotional eating. I think this is really important 32:33 because we don’t address the trauma issue enough with clients and we need to 32:38 be looking at that. There is a huge trauma effect out there these days that is I don’t want to say leading to or 32:45 causing but it is definitely contributing to chronic illness and it’s not being talked about enough. So we 32:52 really need to be talking about this and addressing this trauma aspect. Now the next GLP that one that I want to talk 32:59 about is trespathide. This is a dual agonist. It takes center stage. It is my 33:05 favorite GLP one. Trisepatide is marketed as Mangjaro for type 2 diabetes 33:11 and Zepbound for chronic weight management and it represents the next 33:16 evolution in increantbased therapy. This is a dual agonist a 39 amino acid 33:23 synthetic peptide structurally based on the human glucose dependent insulin tropic peptide so GIP sequence but 33:31 modified to activate both the GIP receptors and the GLP1 receptors. So the 33:37 addition of the GI GIP agonism to the GLP1 agonism appears to create this 33:46 synergistic effect that goes beyond simply adding the two mechanisms together. So the GIP like GLP-1 is an 33:55 increant hormone secreted by what is called the K cells in response to nutrient intake. It enhances glucose 34:02 dependent insulin secretion but it also effects on atapost tissue metabolism 34:09 potentially improving the insulin sensitivity in fat cells and influencing 34:14 how the body stores and metabolizes fat. So some research suggests that GIP may 34:20 also have effects on energy expenditure though this remains an area of 34:26 investigation. So basically what we’re saying is this drug may actually help 34:32 people who are insulin resistant or insulin sensitive, not just somebody who 34:38 has problems with glucose control. So, this is super exciting because it opens 34:43 up the door for all of these people for decades that we’ve been trying to manage with insulin resistance and trying to 34:50 prevent diabetes and honestly most of the time have been unsuccessful 34:56 unless you can keep your diet at 50 grams of carbs or less a day, which is extremely difficult. Um, and take some 35:04 supplements that may or may not work and or take some metformin that may or may not help. this drug actually really 35:11opens that up and helps in that capacity. So there was a clinical trial 35:17 called the surmount clinical trial which demonstrated that trespathide produces 35:22 even more substantial weight loss than semiglutide. In the surerount one trial published by uh J tree I might have said 35:31 that wrong. I apologize if I slaughtered your name and colleagues in the New York England Journal of Medicine in 2022. 35:38 Participants receiving the highest dose of trespide, which is 15 milligrams, achieved an average weight loss of 20.9% 35:47 of their body weight over 72 weeks, compared to 3.1% with placebo. This 35:54 level of weight loss approaches what’s typically only seen in beriatric surgery. So, this is amazing because if 36:02 this medication works and we don’t have to do beriatric surgery, stomach stapling basically, um, oh my gosh, it’s 36:11 amazing. There are so many complications and risks that go with stomach stapling and the different procedures that they 36:17 do these days. People don’t absorb their nutrients properly. They have to do liquid nutrients. It’s very complicated. 36:24 It’s very challenging. Many of these people gain their weight back. Um, and 36:30 this procedure is not fun to go through. So, if we could change that and change 36:35 the lives of people who’ve really been struggling, it is amazing. And I will tell you that I have seen this work. I 36:42 have seen people lose 100 150 pounds on these medications over a year or two 36:50 period of time. It is definitely slower than beriatric surgery on some standpoints, but that is okay. You don’t 36:56 want that rapid weight loss. It’s not good for you. It’s not healthy for you. It doesn’t look well. You know, we want 37:03 to do this safely and effectively in the best way that we can possibly do that for you. Now, the adverse effect profile 37:10 is similar to semiglutide. It’s dominated by gastrointestinal effects. 37:15 Nausea, diarrhea, decreased appetite, vomiting, constipation. These were all commonly reported in the surmount 37:22 trials. And like semiglutide, tricepide carries a blackbox warning regarding the 37:27 thyroid sea cell tumors based on the rodent data and it shares the same contra indications in patients with a 37:34 family history of thyroid cancer and men too. So the mechanism behind why 37:40 tepatide often produces more substantial weight loss than GLP-1. The agonism 37:45 alone remains under investigation, but it may relate to the complimentary effects on the different aspects of 37:51 energy homeostasis or to GIP’s effects on atapost tissue and potentially on 37:58 central central nervous system pathways that GLP1 alone doesn’t fully address. 38:03 Now patients often report even more profound reductions in food noise with tricepide compared to GLP1 and uh sorry 38:12 GLP1 the agonists through this is anecdotal and hasn’t been regularly 38:17 quantified in quality studies. So I’ve done both uh personally and in my 38:22 practice. I really like trespide better than semiglutide. For me I had too many side effects with semiglutide. uh I had 38:30 less side effects with trespathide. I also plateaued on semiglutide which I 38:35 didn’t really care for. And with Tresepide, I haven’t plateaued and I’ve been able 38:42 to lose about 25 pounds in um a year and a half and I’ve been able to maintain 38:49 that. Um and I continued to use it because I do have a strong family history of cardiovascular disease. And 38:56 if this could help me so that I don’t follow my family lineage with cardiovascular disease, I am all for 39:03 trying to do that. I’ve watched too many of my family members suffer from this. I’ve lost my dad at a very young age. I 39:09 lost my grandfather at a young age to it. All of their brothers to this. And I don’t want to be that same person. So 39:16 that is why I chose to do that. And I think it’s really important for us to take a look at that and understand that. 39:24 Now, I know this has been a really long podcast and I don’t typically do podcasts this long. I have a whole host 39:31 of information on additional peptides. So, I’m going to break this up for you 39:36 guys and I’m going to do another episode and we’re going to pick up where we left off here with these peptides so that we 39:43 can actually start to dive into different peptides as well. So, check 39:48 out my next podcast show when we’re going to dive into the peptides that 39:54 talk about sexual wellness, immune function, and all the other cool things 39:59 that we can do with peptides. So until then, remember to like, share, and 40:04 subscribe. It really helps us get out to other people and share our information, 40:10 and join us for our next episode as we continue the talk about peptides. 40:15 Welcome to Let’s Talk Wellness Now, where we bring expert insights directly to you. Please note that the views and 40:21 information shared by our guests are their own and do not necessarily reflect those of Let’s Talk Wellness Now, its 40:28 management, or our partners. Each affiliate, sponsor, and partner is an 40:34 independent entity with its own perspectives. Today’s content is provided forformational and educational 40:40 purposes only and should not be considered specific advice, whether financial, medical, or legal. While we 40:48 strive to present accurate and useful information, we cannot guarantee its completeness or relevance to your unique 40:56 circumstances. We encourage you to consult with a qualified professional to address your 41:01 individual needs. Your use of information from this broadcast is entirely at your own risk. By continuing 41:08 to listen, you agree to indemnify and hold Let’s Talk Wellness Now and its 41:14 associates harmless from any claims or damages arising from the use of this 41:20 content. We may update this disclaimer at any time and changes will take effect 41:26 immediately upon posting or broadcast. Thank you for tuning in. We hope you 41:31 find this episode both insightful and thought-provoking. Listener discretion 41:36 is advised.The post Episode 256 – How Peptides Work, Benefits, and FDA-Approved vs Off-Label Use Explained first appeared on Let's Talk Wellness Now.

Have you ever left a doctor's appointment with a prescription but still felt like something was missed? If you have Hashimoto's, you are not alone. In this episode, Dr. Aaron Hartman, a triple board-certified physician, breaks down why bad medical advice and Hashimoto's are more connected than most patients realize, and exactly what you can do about it. You will learn: Why medical error affects autoimmune patients more than you think The four root causes behind every autoimmune disease What kind of provider to look for when you feel stuck Hit play to get started.   Episode 129 about LDN with Pharmacist Steve Anderson   Dr. Hartman's book "UnCURABLE - From Hopeless Diagnosis to Defying All Odds"   JOIN THE HEALTH WITH HASHIMOTO'S COMMUNITY Unlock your wellness journey with the free Health with Hashimoto's community! Join a supportive community that's here for you every step of the way. The Health with Hashimoto's community is on Skool: https://www.skool.com/health-with-hashimotos/about   Find all links on my resource page: https://healthwithhashimotos.com/resources/   ABOUT THE PODCAST & ESTHER: The Health with Hashimoto's podcast will help you explore the root causes of your autoimmune condition and discover holistic solutions to address your Hashimoto's thyroiditis. It is hosted by Esther Yunkin, a registered nurse, holistic health educator, and Hashimoto's warrior.   This podcast is for informational and educational purposes. Please discuss any questions or concerns with your healthcare professional. These statements have not been evaluated by the Food and Drug Administration. Products mentioned are not intended to diagnose, treat, cure or prevent any disease.

Ep. 107- Reducing food fear when you have chronic health issues by Erin Kenney, MS, RD, LDN, HCP

On this episode of danatech Talks, a special series from The Huddle: Conversations with the Diabetes Care Team, Dana Moreau is joined by Amy Hess-Fischl, MS, RD, LDN, CDCES, to explore the real-world challenges of prescribing diabetes technology. Amy shares practical strategies for navigating coverage pathways, documentation requirements, denials, and affordability, while offering workflow tips to help providers streamline access for their patients. This episode was supported by educational grant funding from Abbott. Explore the latest in diabetes technology as well as trainings and resources on danatech: danatech l Diabetes Technology Education for Healthcare Professionals Listen to the first episode of our danatech Talks diabetes technology series: https://thehuddle.simplecast.com/episodes/basics-diabetes-technology-for-health-care-professionals Listen to more episodes of The Huddle at https://www.adces.org/practice/the-huddle-podcast Learn more about ADCES and the many benefits of membership at adces.org/join. The Huddle Podcast is edited by JAG Podcast Productions: https://jagpodcastproductions.com/ Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

Petra's Journey to the Pros! Petra Rack, MS, RD, CSSD, LDN is a Performance and Sports Dietitian with extensive experience fueling elite and high-performance athletes. She currently serves as the Head Dietitian for Chicago Fire FC, where she leads nutrition strategy to optimize player performance, recovery, and overall health through evidence-based fueling protocols, education, and daily performance support.Petra holds a Master of Science in Kinesiology and Exercise Science and is a Registered Dietitian (RD), Licensed Dietitian (LDN), and Board-Certified Specialist in Sports Dietetics (CSSD)—a credential representing advanced expertise in sports nutrition.In addition to her work in professional soccer, Petra is the Founder of Petra's Eats RD LLC, where she provides individualized nutrition consulting, team education, meal planning, and performance-focused programming for athletes and active individuals. Her background spans collegiate and professional sport environments, giving her a comprehensive understanding of the demands placed on athletes at every level.Petra's approach emphasizes translating nutrition science into practical, sustainable strategies that enhance performance, support recovery, and promote long-term health. She is deeply committed to empowering athletes with the confidence and knowledge to fuel their bodies effectively, both in sport and in life.Looking to break into the field with confidence! Check out my 1:1 mentoring services! www.sportsrdsnippets.com⁠ This episode is sponsored by G2G Protein Bar! If you're a sports RD and are interested in samples, email me at liz@sportsrdsnippets.com or DM Sports RD Snippets on instagram and I'll connect you with Coby Childs for your samples. Looking  to try for yourselves? G2G has also got you covered : Use the code sportsrd15 for 15% your order https://g2gbar.com/discount/sportsrd15

Welcome back to our weekend Cabral HouseCall shows!   This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track!   Check out today's questions:    Savanna: Hi Dr Cabral. My daughter was diagnosed with PANDAS through blood work after i noticed âlot of behavioral regression. She has also been recently diagnosed with level one, high functioning autism. I feel like a detective trying to figure out whats causing these flares. Some months she has seemingly zero symptoms. Then something sets it off (of course the sickness is one culprit causing the PANDAS) but over laps into autistic behaviors. I guess Im trying to ask for help in this mystery of triggers. Also suggestions of where to start to boost her immune system to prevent the sickness in the first place. I feel so discouraged as a parent not knowing how to help my child and watching her suffer. Just as I think I find a good supplement, it stops working. Such as valerian. We were using it as one calming aid and it worked for months and now all the sudden doesnt seem to be doing anything. This has happened with supplements in the past. I did your heavy metal detox and parasite cleanse with her a few years ago. Thnx                                                                                         Yvonne: As a post-menopausal woman, according to my gynecologist, I am not eligible for bioidentical hormones.  Is it ok to take DHEA after a certain age due to ongoing menopause symptoms of facial aging, insomnia, vaginal dryness etc and, if so, what dosage?                                                                            Emily: Hi Dr Cabral, I am currently working through an autoimmune face rash. I am working with a local integrative functional doctor who is recommending low dose naltrexone, and many other items. What are your thoughts on LDN? Harmful, helpful? How long should one stay on it?     Laura: Hi, I'm interested in what ingredients are ok in supplements and food.. for example, hydroxypropyl methylcellulose in baking or in supplements, different gums, which additives are ok? Thank you     Sheena: HI Dr.C! Hope you and your team are well. I'm a 45 year old in perimenopause and would like to prevent osteoporosis. Could you give me some advice on what's the best way to do this? I take foundational level 3 plus added vitamin D, magnesium, zinc and vitamin b. complex. I'm not not taking any calcium supplements except from my multi. Is this a prob? Do I need a special protocol for perimenopause support and osteo? Any advice and recommendations will be appreciated! thank you!     Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions!      - - - Show Notes and Resources: StephenCabral.com/3641 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

Today's guest is Rachel Swanson — MS, RD, LDN — one of the most in-demand nutritionists in the country, known for helping people optimize performance using deeply science-backed, totally personalized care. She's also the author of the brand-new book Trying!: A Science-Backed Plan to Optimize Your Fertility. On today's episode, Ali and Rachel flip the fertility conversation on its head with what Rachel calls Fertility 2.0 — a proactive, preventative approach that goes way beyond eggs and sperm to focus on the whole body: your gut, metabolism, sleep, oral health, even your partner's kissing hygiene (yes, really). This convo was originally aired as part of Fertility Rally Live #10.For more on Fertility Rally, follow IG: @fertilityrallyFor more on Rachel, go to www.rachelswanson.comIG: @rachelsrxEPISODE SPONSORS: THE WORK OF ART BOOK SERIESAli's Children's Book Series about IVF, IUI and Family Building Through Assisted Reproductive Technology https://www.infertileafgroup.com/booksThe latest book in the Work of ART series, “You Are a Work of ART," is for every kiddo born through ART -- and the people who love them.Order "Work of ART," "Beautiful Bird" and "You Are a Work of ART," now at https://www.infertileafgroup.com/booksFERTILITY RALLYIG: @fertilityrallywww.fertilityrally.comNo one should go through infertility alone. Join the Worst Club with the Best Members at fertilityrally.com. We offer 5 to 6 support groups per week, three private Facebook groups, tons of curated IRL and virtual events, and an entire community of more than 500 women available to support you, no matter where you are in your journey.Join today at link in bio on IG @fertilityrally or at www.fertilityrally.com/membershipPHERDALIG: @pherdal_sciencePherDal is the world's first and only FDA-cleared, sterile, at-home insemination kit designed to help people build their families in the comfort of home. Created by parents who've been there, PherDal is safe, simple, and affordable—putting more options in your hands as you grow your family. Explore at PherDal.com.Go to PherDal.com today and use code INFERTILEAF for $10 off.BELIIG: @belibabywww.belibaby.com Are you thinking about growing your family? Whether you're just starting to plan or are actively trying to conceive, preconception health is key. Beli has vitamins to help both women and men optimize their health before pregnancy. With essential nutrients like Folate, Iodine, and Zinc, Beli ensures your body is ready for this exciting next step. Give yourself and your future baby the best foundation for a healthy start.Visit Belibaby.com today and use code IAF15 for 15% off your first order. Our Sponsors:* BetterHelp makes it easy to get matched online with a qualified therapist. Sign up today and get 10% off at BetterHelp.comOur Sponsors:* BetterHelp makes it easy to get matched online with a qualified therapist. Sign up today and get 10% off at BetterHelp.com Support this podcast at — https://redcircle.com/infertile-af-infertility-and-modern-family-building-through-art/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Kendall Mackintosh, MS, CNS, LDN, INHC is a clinically trained nutrition expert who blends evidence-based science with integrative health coaching to address root causes—not just symptoms. With a focus on metabolic health and sustainable lifestyle change, Kendall helps clients turn complex nutrition science into practical, life-changing results. In this episode, Dr. Tro, Dr. Brian, and Kendall talk about… (00:00) Intro (02:19) How Kendall became involved in the MAHA movement (15:45) Medical misinformation and getting de platformed (18:22) The low-hanging fruit you can take advantage of to help protect your family's health (23:26) Glyphosates, heavy metals, micro plastics, mold, and parasites (32:36) Testing for mold, heavy metals, and other toxins (34:29) Parasite tests (39:11) Fasting and gut health (43:57) The vaccine religion (50:16) Moms Across America (58:25) Outro For more information, please see the links below. Thank you for listening! Links: Please consider supporting us on Patreon: https://www.lowcarbmd.com/ Kendall Mackintosh: Website: https://kendallmackintosh.com IG: https://www.instagram.com/kendall.mackintosh/ X: https://x.com/healthy_kendall Dr. Brian Lenzkes:  Website: https://arizonametabolichealth.com/ Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author Dr. Tro Kalayjian:  Website: https://www.doctortro.com/ Twitter: https://twitter.com/DoctorTro IG: https://www.instagram.com/doctortro/ Toward Health App Join a growing community of individuals who are improving their metabolic health; together.  Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.  Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888  Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US Learn more: https://doctortro.com/community/