Podcasts about Homocysteine

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Homocysteine

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Best podcasts about Homocysteine

Latest podcast episodes about Homocysteine

The Health Fix
Ep 592: Brain Fog, Fatigue & the Truth About Inflammation

The Health Fix

Play Episode Listen Later Dec 31, 2025 58:06


Have you ever said, "I just don't feel like myself anymore" — even though your labs look normal? In this episode of the Health Fix Podcast, Dr. Jannine Krause breaks down why inflammation starts in the brain, how it drives fatigue, brain fog, cravings, hormone imbalance, and accelerated aging — and why 2026 is the year to stop suppressing symptoms and start correcting root causes. Inflammation isn't just a body problem. It's a brain health issue first. Your brain uses 20% of your daily calories, and when inflammation is present, it shifts into defensive mode, not performance mode. That's when clarity disappears, energy crashes, and nothing feels like it's working anymore.

Intelligent Medicine
ENCORE: Leyla Weighs In With an Essential Guide for Navigating Supplements

Intelligent Medicine

Play Episode Listen Later Dec 26, 2025 23:18


Nutritionist Leyla Muedin details key aspects of supplement use and addresses frequently asked questions. Topics include the importance of targeted supplementation, the rationale behind personalized dosages, best practices for starting new supplements, and managing common issues like nausea and bright yellow urine. Leyla also explains why some supplements may cause gastrointestinal discomfort and provides guidance on how to adjust dosages for optimal results. Emphasis is placed on the benefits of pharmaceutical-grade supplements available on Fullscript and the necessity of regular blood tests to fine-tune supplementation.

Intelligent Medicine
Intelligent Medicine Radio for December 20, Part 1: Cocoa Ingredient that Slows Aging

Intelligent Medicine

Play Episode Listen Later Dec 22, 2025 43:00


Popular media leverage weak study to criticize RFK Jr.'s rethink of standard recommendations for saturated fat avoidance; Poor quality plant-based diets hike cardio risk; A listener complains his lp(a) is going up with age despite his healthy diet, lifestyle; Scientists pinpoint cocoa ingredient that slows aging; Berry proanthocyanidins preserve brain power; Tattooing may promote inflammation, undermine immunity.

the UK carnivore experience
Emergency Medicine Meets Metabolic Health

the UK carnivore experience

Play Episode Listen Later Dec 11, 2025 53:22


In this conversation, emergency medicine specialist Ankur Verma discusses the intersection of emergency medicine and metabolic health, particularly in the context of the Indian population. He challenges common myths about vegetarianism, highlights the importance of understanding cardiovascular health through data, and emphasises the role of nutrition in recovery. Verma also delves into the implications of vitamin D and B12 deficiencies, the dangers of visceral fat, and the need for informed dietary choices. Throughout the discussion, he shares personal experiences and insights from his practice, advocating for a more holistic approach to health and wellness.Chapters00:00 Introduction to Emergency Medicine and Its Challenges03:06 The Vegetarian Myth: Health Implications in India05:50 Understanding Heart Health: The Role of Diet09:01 Homocysteine and Cardiovascular Risk Factors11:50 The Lipid Hypothesis: Rethinking Heart Disease15:04 Patient Insights: Nutrition and Heart Health17:57 Vitamin D and Its Importance in Health21:00 The Impact of Visceral Fat on Health26:05 Understanding Visceral Fat and Its Implications30:10 The Role of Carbohydrates in Fat Accumulation33:39 Exploring Brain Detoxification Mechanisms35:13 The Impact of Dairy on Health39:12 Questioning Medical Guidelines and Practices43:27 The Importance of Nutritional Awareness47:21 The Role of Doctors in Patient EducationAnkur's LinksInstagram - @thecarnivore.epLinkedIn - Dr. Ankur VermaX - @ anksv25

The Gut Goddess Show with Kezia Hall
Ep 333: Homocysteine: The Hidden Marker Linked to Mood, Memory & Hormones

The Gut Goddess Show with Kezia Hall

Play Episode Listen Later Dec 3, 2025 32:40


In this episode I'm diving into one small but powerful blood marker you've probably never been offered at the GP: homocysteine. We look at: What homocysteine actually is and why it matters for your mood, memory and hormones How B6, B12 and folate can help lower homocysteine The Oxford VITACOG trial showing B-vitamins can slow brain shrinkage in people with mild cognitive impairment Follow-up research showing B-vitamins work best when omega-3 levels are good – why your brain needs both B-vitamins and omega-3s together Practical ways to support healthy homocysteine levels through food, supplements and testing Studies mentioned in this episode: Smith AD et al. Homocysteine-Lowering by B Vitamins Slows the Rate of Accelerated Brain Atrophy in Mild Cognitive Impairment (PLoS ONE, 2010): https://pubmed.ncbi.nlm.nih.gov/20838622/ PubMed Oulhaj A et al. Omega-3 Fatty Acid Status Enhances the Prevention of Cognitive Decline by B Vitamins in Mild Cognitive Impairment (J Alzheimers Dis, 2016): https://pubmed.ncbi.nlm.nih.gov/26757190/ PubMed Resources & links: Book a ROOT deep-dive session with me: https://foodforthebrain.org/product/homocysteine-hcy/  

Intelligent Medicine
Aged Garlic Extract's Impact on Periodontal and Cardiovascular Health, Part 1

Intelligent Medicine

Play Episode Listen Later Nov 19, 2025 30:41


Clinical Pharmacist, Author, Board-Certified Clinical Nutritionist, and Health Expert Jim LaValle details the many health benefits of aged garlic extract, particularly its impact on periodontal disease. He reveals exciting new research findings that show Kyolic Aged Garlic Extract supplements can significantly reduce periodontal pocket depth -- a key indicator of gingivitis and periodontal disease progression. He also highlights the role of aged garlic extract in reducing inflammation and improving gum health, which in turn has significant implications for cardiovascular and cognitive health. The conversation also touches on various formulations of aged garlic extract available from Kyolic, the importance of integrative approaches to health and wellness, and updates on the latest trends in anti-aging medicine, including peptides and GLP-1 agonists.

The Low Carb Athlete Podcast
The Real Truth About Cholesterol & Heart Disease Research with Debbie Potts

The Low Carb Athlete Podcast

Play Episode Listen Later Oct 30, 2025 69:43


The Real Truth About Cholesterol, Heart Disease & Cardiovascular Health SUMMARY What if your cholesterol isn't trying to kill you—it's trying to protect you? In this solo deep-dive, Coach Debbie Potts breaks down the outdated cholesterol myths and reveals the root-cause truth behind cardiovascular disease. Drawing from the work of Dave Feldman, Dr. Ben Bikman, Dr. Paul Mason, Ivor Cummins, and Dr. William Davis, Debbie explains why heart disease is an inflammatory, metabolic, and endothelial problem—not a cholesterol problem. Learn which markers truly predict risk, how to interpret your labs beyond LDL, the role of genetics and epigenetics, and what it really takes to reverse plaque and rebuild a resilient metabolism. If you're ready to move beyond fear and finally understand your cardiovascular health through the lens of functional, ancestral, and root-cause medicine, this episode is your roadmap. KEY TAKEAWAYS LDL isn't "bad"—oxidized, inflamed LDL in a damaged arterial wall is. Heart disease = terrain dysfunction: insulin resistance, oxidative stress, mitochondrial damage, and loss of nitric oxide. ApoB + inflammation predict risk far better than total cholesterol. Context matters: High LDL in a low-inflammation, insulin-sensitive body ≠ the same risk as in a high-inflammation body. Saturated fat isn't the enemy; oxidized seed oils and sugar are. You can't out-supplement poor habits. Sleep, stress regulation, circadian alignment, and daily movement build vascular resilience. Plaque can stabilize or regress when you heal the root causes. The WHOLESTIC Method™ integrates nutrition, movement, sleep, stress, digestion, hydration, and happiness to rebuild your health from the inside out. TESTS & TOOLS MENTIONED - talk to your provider! ApoB (< 80 mg/dL optimal) LDL-P (< 1,000 nmol/L) Triglyceride : HDL ratio (< 1) hs-CRP (< 0.5 mg/L) Lp(a) (< 30 mg/dL) Fasting Insulin / HOMA-IR (< 5 µIU/mL / < 1.0) Coronary Artery Calcium (CAC) Score (0 = clean) CCTA / Cleerly AI Analysis for plaque composition Carotid IMT, Omega-3 Index, Homocysteine, Vitamin D + K2

Intelligent Medicine
From LDL to HDL: The Complete Guide to Cholesterol, Part 1

Intelligent Medicine

Play Episode Listen Later Sep 24, 2025 33:47


September is Cholesterol Education Month. In this episode of Intelligent Medicine, Jim LaValle, a clinical pharmacist and certified clinical nutritionist, details cholesterol's importance and its implications for cardiovascular health. He delves into the nuances of cholesterol types, the historical shifts in perceptions of cholesterol, and how dietary and lifestyle factors influence cholesterol levels and cardiovascular risk. Jim provides expert insights into the roles of LDL and HDL cholesterol, the significance of cholesterol particle size, the impact of carbohydrates on cholesterol, and the benefits of aged garlic extract and other supplements. The conversation emphasizes the importance of comprehensive lipid testing, understanding individual risk factors, and integrating both lifestyle modifications and, when necessary, medications into cardiovascular preventive strategies. The episode concludes with a discussion on the role of health policies and the future of integrative health approaches.

Get Pregnant Naturally
AMH: What the Numbers Really Mean for Your Fertility

Get Pregnant Naturally

Play Episode Listen Later Sep 22, 2025 18:29


If you've been told your AMH is “too low” for your age, or that it means your chances of conceiving are slim, this episode is for you. AMH is not the final word on your fertility, it's a marker that can give us valuable clues about your health. You'll learn: What AMH levels typically look like across different ages. Why low AMH deserves closer attention. Which additional labs give a fuller picture beyond AMH alone. How women in our Fab Fertile community have conceived with their own eggs even with AMH as low as 0.02 ng/mL. I'm Sarah Clark, founder of Fab Fertile. For over a decade, my team and I have helped hundreds of couples improve their chances of pregnancy success, whether naturally or through IVF. We specialize in supporting those with low AMH, high FSH, diminished ovarian reserve (DOR), premature ovarian insufficiency (POI), and recurrent pregnancy loss through functional testing and personalized fertility strategies. This episode is especially for you if: You've been told your AMH is too low and donor eggs are your only option. You've had failed IVF cycles and want to understand if AMH is playing a role. You want to learn how to interpret AMH through a functional fertility lens, not just a conventional numbers-only approach. Not sure where to start? Download our most popular guide: Ultimate Guide to Getting Pregnant This Year If You Have Low AMH/High FSH it breaks everything down step by step to help you understand your options and take action For personalized support to improve pregnancy success, book a call here. --- TIMESTAMPS [00:00] AMH: What the Numbers Really Mean  [00:01:00] Who This Helps: Low AMH, High FSH, DOR, POI, Failed IVF [00:01:50] AMH Levels by Age: Cleveland Clinic Benchmarks Explained [00:02:40] Does AMH Predict Pregnancy? Egg Quantity vs. Egg Quality [00:03:20] Functional Fertility Lens: What Low AMH Is Signaling [00:04:20] Tests Beyond AMH: Day-3 FSH, Estradiol, and AFC Ultrasound [00:05:40] Thyroid & Fertility: Optimal TSH, Free T4/T3, Antibodies (+ Free Guide) [00:07:20] Hidden Inflammation: hsCRP, Homocysteine, MTHFR & Egg Quality [00:08:50] Vitamin D, Iron & Ferritin: Nutrient Deficits That Lower AMH [00:10:40] Gluten/Celiac & Autoimmunity (ANA) + When to Pause IVF & Heather's Success --- RESOURCES

The Cabral Concept
3501: Hives on Face, Sensitivity to Tomatoes, Omega-3 Levels, Weighted Vests, Ovarian Cysts (HouseCall)

The Cabral Concept

Play Episode Listen Later Sep 6, 2025 15:54


Welcome back to our weekend Cabral HouseCall shows!   This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track!   Check out today's questions:    Ashley: Hi Dr. Cabral, love what you've done for the health industry - so much so that I recently graduated as an IHP L2 and will be attending RHS this Fall! I'm writing as I've been experiencing itchy, stinging hives on my face (typically around the chin, mouth and lower cheek area) for 6 months; once the inflammation on the hives settle down I'm left with what appears to be a whitehead. If popped, the skin becomes extremely dry and peels off within 24hrs. I experienced this once in 2018 after a TBI, but worked with a ND (since retired) that resolved my symptoms w/ gut work. I intend to complete the big 5 to asses what's happening, likely followed by a DCD and CBO protocol but would love your thoughts to ensure I'm on the right track and if you have seen these symptoms before. THANK YOU!                                     Tricia: Hi Dr. Cabral - Earlier this year, I had a food sensitivity test done. My bloodwork came in showing above average to tomatoes. The results were 4.7 mcg/ml and anything great than 2 suggests a sensitivity or intolerance. I've been drinking your greens powder every morning and then realized it does have tomatoes but I'm guessing it is a very small amount. Do you think I'm okay to continuing drinking the green powder? I'm working on reducing inflammation in my body. I'm going to retest later this year with your kit. Your test is much more extensive. Thank you!                                                                    Tricia: Hi again, Recent bloodwork showed my Omega 3: EPA at 2.8% by wt is above average. They consider anything above a 2.3 too high. Have you ever seen this before? Not sure why my balance of Omega 3 fatty acids are shifting towards EPA. I was taking your fish oil but have stopped temporarily. All other numbers for Omegas are in range. My total Omega 3 is in range at 7.5. Omega 6-total in range at 39.4. AA/EPA Ratio in range at 4. Homocysteine is 7.7 mcg/dl in range. Omega 6/3 ratio is 5.2. Can I get your opinion please? I know you can't diagnose or treat. I just want your opinion of what it could be and what I should do. Should I continue to take fish oil? I do eat Wild Salmon about 3 times a week. My HS-CRP is 4.1. Thanks for any guidance.                                        Jenny: Hi Dr Cabral - Weighted vests seem to be the latest fitness craze. What is your opinion of them? Thank you!                             Belinda: Please I have ovarian cyst and PID for over four years and I have been taking antibiotics and it's not helping, what should I do           Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions!    - - - Show Notes and Resources: StephenCabral.com/3501 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

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The Human Upgrade with Dave Asprey
PhD at MIT: The Longevity Molecule That Reverses Aging (250 Studies) : 1316

The Human Upgrade with Dave Asprey

Play Episode Listen Later Aug 19, 2025 68:04


Learn how to slow, and even reverse, your biological age with cutting-edge science on the molecule that controls your longevity. Host Dave Asprey sits down with Dr. Leonard Guarente, an MIT PhD and one of the most respected longevity researchers in the world, to reveal how NAD+, sirtuins, and DNA methylation clocks can help you hack aging, upgrade your mitochondria, and extend your healthspan. This episode gives you the real science, proven by over 250 studies, behind supplements, nutrition, and biohacking tools that actually work for brain optimization, metabolism, and human performance. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR You'll learn why NAD+ is a master regulator of mitochondrial health, how DNA methylation clocks accurately measure biological age, and why boosting sirtuin activity improves resilience, neuroplasticity, and recovery. Dr. Guarente shares insider strategies from decades of functional medicine research, including nootropics, targeted supplements, fasting protocols, and diet adjustments from carnivore to Mediterranean that can shift your metabolism toward longevity. Dave and Dr. Guarente explore advanced biohacks like cold therapy, sleep optimization, and ketosis, plus how to balance these interventions with your genetics, lifestyle, and health goals. You'll also hear about the surprising role of homocysteine in brain aging, how to use lab testing to guide your longevity plan, and why resilience is the ultimate measure of health. You'll learn: • How emotional repression affects brain function, metabolism, and decision-making • Tools for nervous system regulation and emotional healing that drive high performance • Why most people fail without emotional intelligence and internal safety • How somatic awareness can optimize your energy, focus, and relationships • The science of fear, trauma release, and how to turn discomfort into growth • How to coach yourself out of stress, shame, and negative self-talk Whether you want to sharpen your brain, protect your heart, or upgrade your energy systems, this is a masterclass in smarter not harder biohacking for a longer, higher-performing life.Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: NAD+ supplementation, Sirtuin activation, DNA methylation clocks, Biological age testing, Mitochondrial biogenesis, Epigenetic reprogramming, Pterostilbene benefits, Nicotinamide riboside (NR), Nicotinamide mononucleotide (NMN), Homocysteine reduction, Oxidative stress repair, Superoxide dismutase (SOD) activation, Functional medicine longevity, Healthspan optimization, Resveratrol bioavailability, Menopause mitochondrial support, Phenylbutyrate and protein folding, High-fat diet longevity studies, Neurodegenerative disease biohacking, INCHIANTI aging study Thank you to our sponsors! Screenfit | Get your at-home eye training program for 40% off using code DAVE https://www.screenfit.com/dave. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • Elysium Website. Use code ‘UPGRADE25' for 25% off the first month of a monthly subscription to any Elysium supplement: https://www.elysiumhealth.com/ • Dave Asprey's Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Introduction to NAD & Sirtuins 0:59 — Intro 7:04 — Animal vs Human Aging Studies 10:07 — Discovery of Sirtuins 14:43 — NAD's Role in Aging 15:34 — Resveratrol vs Pterostilbene 23:13 — Timing NAD Supplementation 36:34 — Diet & Lifestyle Factors 50:05 — Elysium's Basis & Signal 1:00:03 — Future Clinical Trials 1:05:14 — Psychology of Aging & Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The School of Doza Podcast
This Gene's a Real MTHFR—Here's What It's Doing to Your Body

The School of Doza Podcast

Play Episode Listen Later Aug 18, 2025 33:25


This Gene's a Real MTHFR—Here's What It's Doing to Your Body This episode unpacks the powerful effects of the MTHFR gene mutation—on your heart, liver, brain, and mood. Learn how this tiny genetic hiccup can impact energy, detox pathways, mental health, and longevity—and what to do if you've got it.   5 KEY TAKEAWAYS Heart Disease Connection – MTHFR mutations elevate homocysteine, increasing risk for arterial inflammation, stroke, and dementia. Liver Strain – MTHFR dysfunction contributes to fatty liver and reduces the body's ability to detox. Glutathione Production – The gene impacts your ability to make antioxidants like glutathione and NAC, which protect against oxidative stress. Mood & Mental Health – MTHFR affects neurotransmitter production, especially serotonin and dopamine, increasing risk of depression and ADHD. You Need Methyl Donors – Supplements like methylfolate, P-5-P, SAMe, and betaine are crucial to bypass genetic bottlenecks and restore methylation function.   FEATURED PRODUCT Bliss, featuring SAMe and betaine (trimethylglycine), supports healthy methylation by donating methyl groups—essential for mood, energy, and detox. With sublingual delivery for rapid absorption, Bliss is ideal for those with MTHFR mutations needing extra support for neurotransmitter production, glutathione synthesis, and liver detox. A must-have if you struggle with low mood, brain fog, or inflammation. Get it here: https://www.mswnutrition.com/products/bliss   TIMESTAMPS 00:00 START – Welcome to the School of Doza 01:00 – Introducing the MTHFR gene and its reputation 02:00 – Genetic testing and what a consult reveals 03:00 – Homocysteine, inflammation, and heart disease 05:00 – Nitric oxide, artery stiffness, and dementia risk 07:00 – Why everyone should test for MTHFR and homocysteine 08:00 – The liver's overlooked connection to MTHFR 09:30 – How inflammation triggers liver enzymes 11:00 – Why even "normal" genes need lifestyle support 12:00 – Folate (B9) deficiency and its link to depression 13:30 – Personal story: low folate, high homocysteine, and recovery 14:30 – MTHFR, liver enzymes, and antioxidant production 16:00 – Glutathione and NAC: made in the liver, suppressed by MTHFR 18:00 – Methylation, DNA repair, and cancer risk 20:00 – GGT as a liver marker for oxidative stress 21:00 – Neurotransmitters and the B vitamins behind serotonin 22:00 – MTHFR, ADHD, and mental health 23:00 – How Bliss supports brain function and neurotransmitters 25:00 – Methyl donors vs. methylated B12 shots 26:30 – Why Bliss works better for many than other B complexes 27:00 – Research on betaine and SAMe: brain, mood, addiction 30:00 – Methylation and NAD, COMT, and why Bliss helps both 32:00 – Final thoughts: lifestyle can suppress even a “normal” gene   RESOURCES MTHFR Overview: https://www.ncbi.nlm.nih.gov/books/NBK66131/ Homocysteine and Heart Disease: https://pmc.ncbi.nlm.nih.gov/articles/PMC12027316/ GGT, Liver, and Glutathione: https://pmc.ncbi.nlm.nih.gov/articles/PMC2696075/ Antioxidants and Diabetes Risk: https://pubmed.ncbi.nlm.nih.gov/39442756/ Neurotransmitters and Depression: https://pmc.ncbi.nlm.nih.gov/articles/PMC4750636/ Methyl Donors and Mental Health: https://pmc.ncbi.nlm.nih.gov/articles/PMC10556504/ Betaine for Addiction and Mood: https://www.sciencedirect.com/science/article/abs/pii/S0278584624001611  

The Metabolism and Menopause Podcast
Use Your Labs to Build a Fat Loss Strategy That Works | MMP Ep. 219

The Metabolism and Menopause Podcast

Play Episode Listen Later Aug 7, 2025 67:04


You've cut the calories. You've tried the workouts. You've pushed through exhaustion and cravings—and still, the weight won't budge.It's not your fault.It's not your discipline.And it's not just age.⚠️ The truth?Most women over 40 are stuck in fat-storing mode—not because they're doing it wrong, but because their hormones, thyroid, blood sugar, and stress signals are screaming for support. And your lab work is the roadmap you've been missing.EVEN if your doctor says it's “normal” we look for optimalBecause doctors can't prescribe you anything until it is out of rangeAnd at that point we are trying to get out of a pretty deep hole.We want to optimize your health, lab levels and take control before things get worse!In this free, value-packed webinar, I'll show you how to:

Wholistic Matters Podcast Series
Understanding Folate: Forms, Whole Food Sources, and Epigenetics

Wholistic Matters Podcast Series

Play Episode Listen Later Aug 7, 2025 48:37


Dr. Daina Parent, ND and Dr. Sarah Clarke, DC, IFMCP engage in an informative clinical conversation about all things folate. From whole food forms to folate's influence on epigenetics, they transform complex biochemistry into a clear, easy-to-follow, and engaging conversation with clinical gems. They discuss the relationship between folate, vitamin B12, and homocysteine on mental health, brain function, and cardiovascular health and cover biomarkers to help clinicians properly test patients for deficiencies. Drs Parent and Clarke highlight throughout the episode the importance of consuming a whole foods diet that emphasizes foods high in natural forms of folate to support whole body health. Podcast Summary 2:10 Folate (vitamin B9) overview – why is folate important and what is it's role in the body? 4:30 Methylation: a folate-dependent process – how is methylation connected to epigenetics and overall healthy functions of body systems 7:00 Foods that contain methyl donors for methylation - including turnip greens, collard greens and other leafy greens 9:00 Methylation and aging 10:00 Natural forms of folate vs. synthetic folic acid 15:10 Why folic acid isn't the ideal for everyone 17:45 Plant sources of folate when consumed in a whole foods diet 21:00 Dangers of the SAD Diet (Standard American Diet) and over consumption of fortified foods with folic acid 23:35 How malabsorption of nutrients due to GI conditions can impact levels of folate in the body 25:00 When we need more folate and lifestyle habits and medications that impact absorption of folate 27:58 Folate's role in mental health, mood and cognition – brain health, brain function, and aging 32:10 Folate and it's connection to cardiovascular health and the importance of B12 and folate in creating balanced homocysteine levels 35:27 Golden Chlorella – superfood with folate and vegetarian source of B12 35:58 How to measure homocysteine and other important biomarkers 41:52 The benefits of running a CBC to help determine folate or B12 deficiencies 44:20 Clinical case that demonstrates the need to find the right form of folate and B12 for each person 45:44 Benefits of whole food form of folate and B vitamins

Prevmed
Everything you Need to Know About Homocysteine and Methylation - Ford Brewer MD MPH (PrevMed Health)

Prevmed

Play Episode Listen Later Jul 24, 2025 62:16


Become a patient: https://prevmedhealth.com/ +1 859 721 1414Take Control of Your Health: https://drfordbrewermd.com/Check out our New Supplements: https://drfordbrewermd.com/shop/Check out the AT HOME Metabolic Risk Assessment Kit: https://drfordbrewermd.com/metabolic-health-screening-kit/

Vitality Radio Podcast with Jared St. Clair
#548 VR Vintage: How Aged Garlic Extract Benefits Every System In Your Body with Jim LaValle

Vitality Radio Podcast with Jared St. Clair

Play Episode Listen Later Jul 2, 2025 55:44


This episode originally aired as #395 on 1/13/24. It's an oldie but goodie so we are sharing it again! What is Aged Garlic Extract (A.G.E.) and how is it different from the garlic we eat? Can this one thing actually lower cholesterol, improve insulin resistance, keep bones strong, boost immunity and detoxification, and prevent dementia? We tend to compartmentalize our bodily systems, but they are all connected and the cardiovascular system is at the head of them all. Learn the science behind how A.G.E. can impact all of our systems, how to take it, how much to take, and what the research actually shows, on this episode of Vitality Radio, where Jared interviews Jim LaValle all about Kyolic Aged Garlic Extract. You'll learn its many benefits and how to use it to improve your overall health. Products:Kyolic Aged Garlic ProductsAdditional Information:#278: The Incredible Benefits of Aged Garlic ExtractLipid tests discussed: NMR LipoProfile® TestCardio IQ®Visit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

Chats with Dr. Purser
Q&A On Fibromyalgia and Homocysteine - Dan Purser MD

Chats with Dr. Purser

Play Episode Listen Later Jun 26, 2025 45:36


This week Dr. Purser met with Lois from End Fibromyalgia with Natural Options! Lois asked all about the REAL cause of fibromyalgia and how our patients benefit from a Low Copper Diet and basic supplementation. If you have widespread pain, this may be GAME CHANGER for you.

Vitality Radio Podcast with Jared St. Clair
#542: VR Vintage: Your Collagen User's Guide: How to Preserve and Build Collagen Naturally

Vitality Radio Podcast with Jared St. Clair

Play Episode Listen Later Jun 11, 2025 38:15


This episode originally aired as #304 on 3/1/23. It's an oldie but goodie so we are sharing it again! Collagen is a major buzzword in health and nutrition today. On today's episode Jared provides a precise protocol for preserving and boosting collagen to help you slow and reverse the signs of aging. You'll discover the true value of collagen for appearance, anti-aging, healthy joints, bones, and teeth, and improved gut and microbiome health. For 25% off of the Collagen Trio use promo code: collagen Protocol:Ultimate Vitality Multi - 3/day with breakfastBiosil - 2/day split between two mealsTotal Body Collagen - 1 scoop/day Optional: Anxiety ReleaseAdditional Information:Episode #303: Collagen, How We Make It, Why We Need It, and How to Build More with SilicaEpisode #242: The Vital Five How To: Your User's Guide to Filling the Gaps in Your DietVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

Nutrients
The Vitamin Link to Neuropsychiatric Disorders

Nutrients

Play Episode Listen Later Jun 6, 2025 10:06 Transcription Available


In this episode of Daily Value, we look at the influence of B vitamins on mental health and neuropsychiatric disorders. The discussion is centered around a recently published meta-analysis suggesting a causal link between B vitamin deficiencies and the development of conditions such as Parkinson's disease, schizophrenia, and Alzheimer's disease. Talking points include the distinct impacts of vitamins B12, B6, and B9 (folate) on brain health, their role in one-carbon metabolism, and findings from various studies on their protective effects.00:00 Introduction to B Vitamins and Mental Health00:45 Understanding the Meta-Analysis02:07 The Role of B Vitamins in One Carbon Metabolism02:47 Homocysteine and Neuropsychiatric Disorders03:19 B Vitamin Supplementation and Cognitive Decline03:55 Vitamin B12 and Parkinson's Disease06:26 Vitamin B6 and Schizophrenia08:27 Folate and Alzheimer's Disease09:02 Conclusion and Key TakeawaysPMID: 39952338PMID: 26757190PMID: 32257364PMID: 30858560PMID: 32424116PMID: 33941768Support the show

The Health Courage Collective
205: Homocysteine: A Lab Test Worth Asking For

The Health Courage Collective

Play Episode Listen Later Jun 4, 2025 19:12


 There is a cheap and easy lab test that can give you a lot of information about your risk for scary things like  heart attack, stroke, dementia, brain shrinkage, osteoporosis and more. It could save your life.  But most doctors won't order it unless you ask them to because they don't know what to do with the results.  But you're about to.  Let's talk about homocysteine.come to my website: www.healthcouragecollective.comemail me: healthcouragecollective@gmail.com

Nutrients
The Nutrient Duo That Could Save Your Mind

Nutrients

Play Episode Listen Later May 26, 2025 8:24 Transcription Available


In this episode of Daily Value, we look into the synergistic relationship between two nutrient classes in supporting brain health and mitigating cognitive decline. Drawing on evidence from past clinical evidence suggesting these two nutrient classes work in tandem to support brain function and health.Discussion Points:-Homocysteine's role in disrupting fatty acid incorporation into cell membranes and amyloid-beta clearance.-Findings from one study, where some 70-year-old participants experienced up to 30% reduction in brain atrophy.-Practical strategies to optimize intake of these nutrients.00:00 Introduction to Brain Health and Nutrition01:06 Understanding Mild Cognitive Impairment01:44 The Role of B Vitamins and Omega-3s02:34 Mechanisms of One Carbon Metabolism03:06 Impact of Homocysteine on Brain Health04:12 Key Studies on Nutrient Synergy07:05 Practical Dietary Recommendations08:07 Conclusion and Final Thoughtshttps://pubmed.ncbi.nlm.nih.gov/22260268/https://pubmed.ncbi.nlm.nih.gov/29480200/https://pubmed.ncbi.nlm.nih.gov/26757190/Support the show

True Health Recovery
The Hidden Homocysteine Danger That Doctors Missed

True Health Recovery

Play Episode Listen Later May 16, 2025 15:43 Transcription Available


Podcast Description: Homocysteine Healing – How Mike Went from Sick to Strong in Just Weekshttps://www.drhughwegwerth.com/post/the-homocysteine-comeback-plan-backed-by-labs-powered-by-scienceHosted by: Dr. Hugh WegwerthEpisode Title: The Shocking Lab Number That Changed EverythingIn this powerful episode, Dr. Hugh shares the story of Mike, a man in his early 30s who was completely failed by the medical system—until he found the right help.Here's what you'll learn:What homocysteine is and why it's so dangerousHow Mike's homocysteine level hit 69 (the highest Dr. Hugh has ever seen in 15+ years)The crippling symptoms Mike dealt with—gastritis, brain fog, pain, fatigue, and moreWhy Mike couldn't gain weight and had to sleep sitting upHow a custom functional medicine plan changed his life in just 2 weeksThe exact supplements used, like Methyl Charge and NAD GoldHow his lab numbers dropped from 69 to 8.5 in just five weeksThe truth about why conventional care fails so many people with chronic health issuesIf you've been suffering and told “your labs are normal”… this episode is your wake-up call.You can get better. You just need the right guide.

biobalancehealth's podcast
How To Prevent a Stroke..Start Early!

biobalancehealth's podcast

Play Episode Listen Later Apr 8, 2025 24:15


See all the Healthcasts at https://www.biobalancehealth.com/healthcast-blog I am not sure if you play THE “WHAT'S THE DISEASE THAT I DON'T WANT TO HAVE GAME with yourself, but since I am a doctor I have spent a lot of time thinking about what diseases I do not want! I started my list in medical school when I witnessed what certain diseases can do to your life.  Medicine has many cures and treatments, yet some diseases that are treated still can negatively change your life forever. Even though losing a limb and amputation were at the top of my list there is one disease that tops my list.  Of course, I also have under stroke the usual scary situations like paralysis, or having an incapacitating heart attack that prevents an individual from taking care of himself or herself. However, my most feared diagnosis is having a STROKE! You may not fully comprehend how a stroke can change your life, but it can affect your speech, your ability to move, to think, to go places, to have a sense of humor, to write and communicate, even to have a sexual relationship with your loved one. A stroke essentially can take away your ability to be the person you have always been, AND it requires that someone must become your caretaker.  That helplessness is something I am most afraid of….We all have our personal fears, but whether you fear having a stroke or not, you should  try your hardest to avoid having one! DEFINITION: a stoke is a medical emergency that occurs when blood flow to the brain is  blocked or a blood vessel bursts. This can damage or kill parts of the brain, which can lead to long-term disability, brain damage, or even death.  This can cause s a loss of function, physical, mental, and  emotional, and loss of one or more of the senses like sensation, speech, sight, hearing and  taste and smell! In my practice at BioBalance Health we always work with our patients to prevent them having a stroke and or heart attack. These two conditions are the biggest villains that steal the joy of our “golden years” from us.  From the start of my BioBalance Health practice, I have incorporated  healthy diet training, exercise options and encouragement, how and what to take to supplement my patients' diet and how to outsmart their genetic makeup so they can be healthier than their parents. All of these lifestyle changes can decrease the risk of stroke and heart attack in a person. So what is it like to have a stroke? First let's go over what symptoms are typical of someone having a stroke. The symptoms of a stroke are multiple, and a person might not have all of them. Weakness on one side of the body Facial drooping on one side of the face Dizziness Numbness Loss of balance Sudden loss of vision. Trouble making sense when speaking Trouble talking, reading or understanding Sudden nausea and vomiting Brief loss of consciousness such as fainting, seizures, confusion, or coma. When someone has one or more of these symptoms it is an emergency, and you should call 911, then start asking the patient to open their eyes, smile, raise both arms and hold them up. Ask them to talk to see if their speech is impaired. Your findings will be helpful to the EMTs who come to the scene. An event is called a stroke, when there is a deficit in physical or mental function and that deficit continues and doesn't go away.  If it the symptoms completely resolve, it is called a TIA- a transient Ischemic attack. It is a warning to see a doctor and make sure you don't have a stroke in the future and it is a wakeup call to stop all poor lifestyle choices.   PREVENTING A STROKE: This last month, the American Heart and Stroke prevention Association released new Guidelines on how to prevent a stroke.  I think talking about the risk factors for stroke and discussing how to prevent having one, is worthy of discussion. Recently the medical guidelines for stroke prevention have been revised, and even though I think a few more things should have been included, the fact that they made the first change in the guidelines in 10 years is a first step. Here is what they advise all people who are aging should do.   #1 See your internal medicine or Family physician regularly, at least yearly #2. Stop sedentary behavior—walk/exercise/ do Yoga, just get out of the chair for the majority of your day! #3. If you are diabetic, they advocate going on Ozempic/Mounjaro to lose weight—that will lower your risk of a stroke, and heart attack.. #4 If you are hypertensive, take your BP medicine every day #5 Follow these lifestyle changes called Life's Essential 8: Your behavior and lifestyle put you at risk for having a stroke:    Healthy diet, low carb Mediterranean diet, no junk food!  Physical activity every day  Achieve a healthy weight,  Make sure your sleep is restful  Stop use of tobacco products, No smoking or vaping  Achieve healthy levels of blood glucose, and blood pressure.  Don't drink more than one 4 oz glass of wine a day  I add these recommendations to theirs for the care of my patients:   Drink ½ your weight in water every day Wat at least half your weight in grams of protein a day Get a Cardiac calcium scan to see if you have arterial plaque. If you do have plaque (arteriosclerosis) then you are at risk for stroke as well. See a cardiologist to be treated preventatively and tested. Option other than a cardiac calcium scan, get a carotid ultrasound to make sure you don't have plaque in the neck vessels that lead to your brain.. Make sure your Homocysteine level is normal (

biobalancehealth's podcast
Reasons Why You Can't Interpret Your Own Lab Results

biobalancehealth's podcast

Play Episode Listen Later Apr 8, 2025 23:09


See all the Healthcasts at https://www.biobalancehealth.com/healthcast-blog There is a new federal rule for lab companies that requires them to report your blood tests to you as soon as they are finished, often even before your doctor has seen them.  This rule, deemed unreasonable, was established by individuals without medical expertise (politicians), who know little about interpreting lab data or the workings of doctor's offices. Sending your lab results to you before doctors can assess them is not a decision rooted in sound medical practice but rather in the notion of individual freedom. While this is important, it does not compare to having an expert interpret your results with you. The law requiring that your lab results be sent to you as soon as they are completed does not consider the fact that these results are not designed for laymen to interpret. Additionally, lab results are meant to be analyzed alongside a patient's medical history, age, gender, and medications.  The results are not tailored to report information specific to your situation, which is how a doctor would interpret them. Lab results often lack layperson-friendly explanations. This new protocol can cause anxiety, as patients may panic over results that appear abnormal, even if they are normal for their specific medical condition and treatment. Furthermore, lab companies only request your age and gender. The factors that doctors evaluate when interpreting your results are diverse and numerous, each influencing the overall interpretation. What are the considerations that doctors add to their interpretation? Menopausal status Medical conditions Healthy normal for young and healthy adults The newest recommended ranges for health Body weight Other lab values seen on the same report The problem with you getting your own lab and interpreting it as written is multifactorial: The lab is sent to you digitally with very little explanation except for reference ranges. There is no information about who you are being compared to. Other women, both men and women? Old women? Young women? Women with symptoms or women who are well without symptoms.  The reporting of the lab results to a patient directly may hide problems that need action or create fears that are unnecessary. Anxiety over your results will continue until your doctor's appointment to discuss … so you may experience unnecessary worry in many circumstances. Reference ranges make many assumptions, but labs don't input vital information about you into their computer. your age of menopause, your weight your height (or BMI) previous illnesses and your medications. if you are on hormones or testosterone   Here is a good example. The test for pituitary hormones FSH and LH. When a woman aged 45 is menopausal, and has a very high FSH and LH, the lab says it is “normal” (in the reference range), yet the woman is having severe hot flashes, night sweats, anxiety, and insomnia.  That is not healthy or “normal”. The same two tests can be used to determine if a person is menopausal. Let's say a 42-year-old woman has elevated FSH and LH, but her estradiol is very high (200-300). To the layperson, this looks like menopause, but in reality, it is the picture of ovulation, not menopause. One has to look at another test, estradiol, to determine whether she is premenopausal and ovulating or menopausal (her estradiol would be very low, and FSH and LH would be high). See the problem? Reference Ranges don't tell you what the doctor is looking for. The same two tests, FSH and LH, are used to diagnose polycystic ovaries (PCO) too.  In women without PCO, the FSH is higher than the LH, but if the LH is greater than the FSH, the diagnosis of PCO should be considered! There is no information about this interpretation in the lab report. Falling within the reference range doesn't guarantee health or absence of symptoms. If patients are to interpret their own lab results, reference ranges should reflect health in every possible scenario. FSH and LH are influenced by BCPs and menopausal HRT. Lab results should be interpreted considering the information regarding BCPs or ERT that the patient is taking. When women are on BCPs and HRT or ERT, their FSH and LH levels are suppressed to an extremely low point. If you are unaware that the patient is taking these hormones, it may appear that the diagnosis is pituitary failure affecting estrogen levels and ovulation. Only doctors can interpret this test. There should truly be a “normal” range for those undergoing hormone replacement therapy, along with a reference range that reflects overall health, rather than merely the average for your geographical area in the US or your age group. Please make an appointment with your doctor to review your lab results so you can understand how they are interpreted. If you have questions about your lab results that are concerning you, schedule a time to discuss them with your doctor. Doctors don't have the time to explain results over the phone or through email—that is what appointments are meant for. Phone calls to doctors' offices are not intended for lab result interpretation. You or your insurance will not compensate the doctor or NP for this service over the phone.   The reference ranges for many tests and medical situations are actually wrong. If you aren't trained as a doctor or Nurse practitioner who interprets metabolic lab results every day, you could get the wrong diagnosis!!! For example, when evaluating a patient for insulin resistance, the reference range was officially changed almost two decades ago. Still, the lab companies have left the normal range very high (insulin> 18). In the revised range, fasting insulin diagnoses insulin resistance if the value is > 10. The resulting outcome is that many people are not diagnosed at a time when they can be easily treated without drugs and are told that they are “normal” when they are really experiencing insulin resistance. This is misleading and just wrong! Lab values are not adjusted to your individual situation.   Many tests are adjusted for gender; however, some are specifically adjusted for women who are menstruating regarding H/H. In other words, men and women have different “normal” H/H levels in the reference range. Women who do not menstruate or who are menopausal should be compared to the same reference range as men, but that does not happen. This leads to menopausal women, who are normal, often being told they have too many red blood cells when that is not the case. Conversely, menopausal women who are truly anemic are told they are normal, which means it takes longer to diagnose their anemia from colon cancer! The H/H should have a reference range that is considered “normal” for a woman's stage in life, depending on whether she is experiencing menstrual periods or not. Many reference ranges are averages for regions of the US and vary between lab companies; therefore, they are not reliable values for comparing patients.   For instance, the Homocysteine test has a normal range that is relatively high, and each lab has different reference ranges. This test serves as a screening tool for MTHFR genetic risk related to embolic stroke and heart disease.   The suggested treatment involves methylated B vitamins; however, the interpretation on the lab printout advises taking B12 and folic acid, which, in my experience, tends to increase the number rather than decrease it. Reference ranges for nutrients, vitamins, and minerals reflect the minimum levels needed for survival, not optimal health. For example, B12 reference range levels for B12 blood levels are listed as 200-1100 pg/ml, yet I was trained to try to achieve 400 -1500 pg/ml. The lower range of the written reference range (200-400) is not healthy. The desired blood levels for vitamins are often controversial, and various medical colleges issue new recommendations on Vitamin D levels each month. Consequently, doctors must determine which level of Vitamin D to recommend for their patients. These institutions not only provide changing reference ranges but also offer differing advice on how frequently to test Vitamin D. This inconsistency arises primarily from the ongoing debate about the minimum acceptable level of Vitamin D. I have more information about your lab results next week that your doctor may not share with you. There is a lot of controversy surrounding the reference ranges on the lab sheet, and you should know the truth in case your doctor doesn't.

The Keto Kamp Podcast With Ben Azadi
#981 Fat Loss Hacks, Muscle-Building Myths, Lab Testing Secrets & How to Fix Insulin Resistance with Jason Theobald

The Keto Kamp Podcast With Ben Azadi

Play Episode Listen Later Apr 5, 2025 67:05


In this episode of the Metabolic Freedom Podcast, Ben Azadi sits down with Jason Theobald—fitness coach, IFBB Pro, and founder of Scooby Health—to deliver a masterclass on building lean muscle, optimizing fat loss, and improving metabolic health. Jason shares his top five exercises for maximum results, why muscle mass is critical for longevity, and how stress, inflammation, and poor insulin sensitivity affect fat loss. They also dive into lab testing, fat-burning supplements, keto cycling, and the power of recovery, mindset, and gratitude. Whether you're a beginner or seasoned lifter, this conversation is packed with practical tools to level up your physique and health.

Intelligent Medicine
The Essential Guide to Detoxification, Part 1

Intelligent Medicine

Play Episode Listen Later Mar 18, 2025 31:19


Decoding Detox: The Science and Application of Detoxification with Neil Levin, Senior Nutrition Education Manager at NOW Foods and Protocol for Life Balance. They delve into the importance of detox in addressing environmental toxins through reducing exposure and enhancing resilience. Key detoxification pathways, including liver phases, antioxidants, glutathione, and methylation, are thoroughly examined. Neil Levin also touches upon issues in the supplement industry, stressing the importance of using reliable sources. Additionally, he shares insights into his advocacy work and emerging trends in supplement research. This episode provides crucial information on how certain supplements can support the body's natural detox processes.

Howards Blend
To Methylate Or Not To Methylate?

Howards Blend

Play Episode Listen Later Mar 15, 2025 7:46


Discuss my thoughts on whether Dimethylglycine or Trimethylglycine is "better" for Homocysteine conversion to Methionine.This is strictly for educational purposes. The information in this video is not meant as a substitute for professional medical advice.Please like, comment and share if you find value in this video. Also, please ask any questions you have about supplements. I'll do a video reply as soon as possible.Resources: https://pmc.ncbi.nlm.nih.gov/articles/PMC4684116/https://cen.acs.org/articles/82/i3/METHYLMERCURY-TOXICOLOGY-PROBED.html#:~:text=%22Glutathione%20can%20be%20pumped%20out,brain%20as%20methylmercury%2Dglutathione.%22https://pmc.ncbi.nlm.nih.gov/articles/PMC4540061/https://www.sciencedirect.com/science/article/pii/S0163725821001182https://www.sciencedirect.com/science/article/pii/S0163725821001182 Image Resource:https://pmc.ncbi.nlm.nih.gov/articles/PMC6635095/ https://www.researchgate.net/figure/Overview-of-de-novo-glutathione-synthesis-Reduced-glutathione-or-GSH-is-a-tripeptide_fig2_5690064 https://lpi.oregonstate.edu/book/export/html/71 https://www.nature.com/articles/hr2011133 https://en.wikipedia.org/wiki/Serine_hydroxymethyltransferase - https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/methylenetetrahydrofolate-reductasehttps://chemtymology.co.uk/2020/11/27/cysteine-and-cystine/ https://fda.report/DailyMed/972f09a7-2aa1-4b1b-a6dc-2c4578a07803 https://www.thoughtco.com/definition-of-precipitate-604612 https://pubchem.ncbi.nlm.nih.gov/compound/Acetyl-p-benzoquinone-imine#section=3D-Conformer https://www.semanticscholar.org/paper/DRUG-METABOLISM-IN-THE-LIVER-Nguyen/4a29c6c4d433685a94b94602c012b8731cba5493https://pubchem.ncbi.nlm.nih.gov/compound/S-_Methylmercury_-L-Cysteine#section=2D-Structurehttps://keymerhealth.com/articles/seafood-mercury/https://onlinelibrary.wiley.com/doi/10.1155/2021/6564585 https://www.sciencedirect.com/science/article/abs/pii/S0304416519300133https://www.jbc.org/cms/10.1074/jbc.M111.265348/asset/822df563-eda2-4f48-a333-d01370a79e9c/main.assets/gr5_lrg.jpghttps://www.researchgate.net/figure/Betaine-metabolism-Metabolic-pathways-involving-betaine-BHMT-betaine-homocysteine_fig11_225081065https://www.acs.org/molecule-of-the-week/archive/c/l-cysteine.htmlhttps://biologydictionary.net/glutamic-acid/https://www.researchgate.net/figure/An-overview-of-the-reaction-catalyzed-by-SHMT-and-its-context-in-the-folate-cycle-A-The_fig1_338995871https://pubchem.ncbi.nlm.nih.gov/compound/5-Methyltetrahydrofolate#section=2D-Structurehttps://pubchem.ncbi.nlm.nih.gov/compound/Tetrahydrofolic-acid#section=2D-Structurehttps://pubchem.ncbi.nlm.nih.gov/compound/135398652#section=2D-Structure

Intelligent Medicine
Biohacking Your Genes: Navigating the Genetic Path to Wellness, Part 1

Intelligent Medicine

Play Episode Listen Later Mar 11, 2025 29:47


In this episode of the Intelligent Medicine Podcast, Dr. Ronald Hoffman interviews Dr. Sharad Paul, a New Zealand physician, on his book, "Biohacking Your Genes: 25 Laws for a Smarter, Healthier, and Longer Life." They discuss how genes serve as a blueprint but not a destiny, stressing the role of lifestyle and habits in managing genetic risks. Dr. Paul expands on the impact of diet, supplements, and exercise tailored to genetic makeup, citing his holistic approach versus extreme gene-editing biohacking. The conversation touches on vitamin D's role in health, the misconception about sun exposure, and the relationship between genetics and skin health. Nutrigenomics is explored, illustrating how genetic testing can influence dietary and lifestyle choices, while also covering genetic predispositions related to mood, sodium, and sugar sensitivity. The podcast concludes with actionable tips for optimizing skin health through diet and protective measures.

The Human Upgrade with Dave Asprey
Gary Brecka: The SECRET Blood Marker That Could Save Your Life! (pt. 2) : 1248

The Human Upgrade with Dave Asprey

Play Episode Listen Later Feb 6, 2025 62:00


Could the right form of a single vitamin be the difference between thriving and barely surviving? In this Part 2 conversation, human biologist and longevity expert Gary Brecka reveals the #1 overlooked factor that's wrecking your health: methylation—your body's ability to convert nutrients into fuel. If this process fails, your hormones, energy, and even mental health take a nosedive. Gary and Dave dive deep into the real cause of anxiety, ADHD, and mood disorders, the hidden genetic reason why diets fail, and why Big Pharma isn't talking about this critical health breakthrough. Are you unknowingly setting yourself up for disease? What's the simple fix that can reverse anxiety, gut problems, and even prevent genetic disease? And why is your doctor ignoring one of the biggest markers of longevity? What You'll Learn: • The MTHFR gene mutation—and why it's quietly affecting millions • Anxiety, ADHD, and depression—why these disorders start in your cells, not your brain • The gut-brain connection—how your microbiome controls your mood • Why your “healthy diet” might be hurting you (and what to eat instead) • How nutrient deficiencies are passed from mother to child—and how to stop it • The truth about homocysteine—the blood marker that could predict your lifespan • Why most people are living at 50% capacity—and how to get your energy back Resources: • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Gary Brecka's Website: https://bit.ly/4hlfyti • Gary Brecka's YouTube: https://bit.ly/3E3Aaba • Gary Brecka's Instagram: https://bit.ly/3PNsgFe • Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Danger Coffee: https://dangercoffee.com • Dave Asprey's Website: https://daveasprey.com • Dave Asprey's Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com • The Mold Movie!: https://moldymovie.com/ SPONSORS: -BON CHARGE | Go to https://boncharge.com/ and use coupon code DAVE to save 15%. -Qualia | Go to https://www.qualialife.com/dave15 to get an additional 15% off subscriptions. Timestamps: • 00:00 Trailer • 00:31 What Is Methylation? • 01:37 MTHFR, Folate & Your Health • 04:17 How Methylation Affects Disease • 06:41 Nutrient Deficiencies & Health Risks • 07:09 Why Blood Work Matters • 11:44 Homocysteine & Heart Health • 21:37 Catecholamines & Anxiety • 34:28 The Link Between Nutrients & Mood • 34:48 How Catecholamine Ratios Affect Mental Health • 35:39 Personal Health Struggles & Lessons • 36:25 The Role of Methylation in Wellness • 37:57 Methylation & Relationship Dynamics • 39:49 Hidden Dangers of Mold Toxicity • 52:55 Hydrogen Water for Health • 01:01:19 Mitochondria's Role in Longevity • 01:02:23 Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Naturally Nourished
Episode 422: Functional Approaches to Neurodegenerative Disease

Naturally Nourished

Play Episode Listen Later Dec 3, 2024 73:04


Are you concerned about cognitive decline for yourself or a loved one? Curious what you can do now to prevent neurodegenerative disease? Tune in to hear us discuss neurodegenerative disease, from dementia and Parkinson's, to depression and anxiety and beyond.    In this episode, we discuss the sharp increase in neurodegenerative disease in recent years and the many possible root causes of these conditions. Learn how addressing the gut, inflammation, toxicity, metabolic health and more can prevent disease or improve outcomes. Plus we discuss the most helpful lab and supplement interventions to support optimal brain function.    Also in this episode: Buy 3 Get 1 Free Naturally Nourished Tea with code FREETEA 5 Day Detox PDF Free Keto Reset Live Masterclass 1/15 Save the Date, Class Starts 1/29 Naturally Nourished Gift Cards What is neurodegenerative disease?  The methylation connection Episode 331 Homocysteine and Methylation Methyl Complete Genetic SNP Testing Cardiometabolic Panel Functional approaches to neurodegenerative disease Gut Health GI Map Stool Test MRT Test Probiotic Challenge  Rebuild Spectrum Probiotic Targeted Strength Probiotic GI Lining Support GI Immune Builder KidsBiotic Inflammation Anti-Inflammatory Bundle EPA DHA Liquid EPA DHA Extra Vitamin D Balanced Blend Cellular Antiox Health Effects of Grape Seed and Skin Extracts and Their Influence on Biochemical Markers Multidefense Dry Farm Wines use code ALIMILLERRD Toxicity Episode 364 EMF and Cell Phone Radiation 10 Day Detox Micronutrient Panel Antioxidant status Cellular Antiox Grassfed Whey Alpha Lipoic Acid CoQ10 Metabolic Health  Keto and neuroplasticity Ketone bodies in neurological diseases: focus on neuroprotection and underlying mechanisms Effects of intermittent fasting on brain metabolism Intermittent metabolic switching, neuroplasticity, and brain health Intermittent fasting and metabolic switching: a brief overview. Role of ketogenic diet in neurodegenerative diseases focusing on Alzheimer diseases Stress Relax and Regulate Calm and Clear GabaCalm Episode 322 Nature as Medicine 4-7-8 Breath Neurohormone Lab Labs Homocysteine

the UK carnivore experience
The Science Behind Folate and Homocysteine

the UK carnivore experience

Play Episode Listen Later Nov 6, 2024 51:44


In this conversation, Stephen Thomas and Richard Smith discuss various aspects of nutrition, particularly focusing on the carnivore diet, its effects on health, and the importance of understanding nutrient absorption and supplementation. They explore topics such as folate and homocysteine levels, the relationship between diet and longevity, the role of cholesterol in heart health, and the impact of electrolytes on anxiety. The discussion emphasises the significance of feeling well and understanding individual health rather than solely relying on numbers and tests. Takeaways Folate is crucial for breaking down homocysteine into methionine. How you feel is more important than just lab numbers. Humans can potentially live to 120 years with the right diet. Dietary sources of nutrients are vital, especially organ meats. Supplements should not replace real food; real nutrition comes first. Histamine intolerance can be managed by dietary adjustments. Thyroid health may require specific supplements like iodine and selenium. Cholesterol is essential for cell formation and nutrient absorption. Electrolyte balance is crucial for overall health and can affect anxiety levels. Community support and engagement are important for health journeys.

More Plates More Dates
Homocysteine, The Vasodilation Brick Wall, And The Optimal Betaine/Trimethylglycine Dosage

More Plates More Dates

Play Episode Listen Later Sep 16, 2024 7:53


Get Pregnant Naturally
Why Addressing Homocysteine Levels Can Boost Egg and Sperm Health

Get Pregnant Naturally

Play Episode Listen Later Sep 9, 2024 38:57


We're digging into how homocysteine impacts fertility. Our goal at Fab Fertile is to reduce inflammation in your body and boost your immune system so you can prepare for pregnancy success. But how can you tell if you have inflammation in the body? A good marker to get tested is your homocysteine. Optimal homocysteine levels are crucial for overall health and high levels can lead to inflammation. Plus, healthy homocysteine levels are essential for egg and sperm health. So, what are the exact steps to improve homocysteine levels and get pregnant this year?   In this episode, you'll learn: 1) What is homocysteine, and why does it matter for fertility (i.e., ovulation, egg health, sperm health, embryo quality, implantation, and pregnancy outcomes) 2) What are the optimal reference ranges for healthy homocysteine levels in the blood 3) Which foods can help improve homocysteine levels 4) Which supplements can help with homocysteine levels (i.e., MTHFR gene variant (60-80% of us have this variant) and how can this impact homocysteine)   --- RESOURCES: Fab Fertile Method https://www.fabfertile.com/what-we-do/   Ultimate Guide to Getting Pregnant This Year If You Have Low AMH/High FSH - https://fabfertile.clickfunnels.com/optinvbzjfsii   --- I just put together a new guide, “Reconnecting With Your Fertility: Preparing Your Body With Diet” that I'm going to give you pro bono (aka, free

Healthy Human Revolution
The Impact of Elevated Homocysteine on Heart Health

Healthy Human Revolution

Play Episode Listen Later Jul 30, 2024 15:23


In this episode, I dive into the topic of elevated homocysteine levels in the context of a plant-based diet. I'll explain what homocysteine is and its role in the body's metabolism, emphasizing the importance of measuring B12 levels. You'll learn about the relationship between homocysteine and methionine, an essential amino acid found in plant-based foods. I provide an overview of homocysteine metabolism and discuss the conversion of methionine to S-adenosylmethionine (SAM). To work with me: https://www.drmarbas.com/ A Big Thank You To Our Sponsors: If you want to work with the best Whole Foods plant-based body recomposition coach, I highly recommend checking out what www.fitvegancoaching.com offers. I did their program and was able to lose 7% of body fat, build lean muscle, and improve my running time. As a loyal subscriber to the newsletter, you get $250 savings on their coaching services. To learn plant-based cooking and get your medical questions answered, join The Healing Kitchen, taught by Brittany Jaroudi and me! Click here to learn more: https://www.drmarbas.com/the-healing-kitchen

The Growth Lab with Dr. Josh Axe
Fix Fertility, Thyroid, Anxiety & Sleep With This Methylation SECRET

The Growth Lab with Dr. Josh Axe

Play Episode Listen Later Jul 9, 2024 32:11


What if I told you that a single biochemical process could be the key to unlocking your body's full potential? In this eye-opening episode of The Dr. Josh Axe Show, we dive deep into the world of methylation - a crucial process affecting over 40% of Americans. Dr. Axe breaks down this complex topic, revealing how it impacts everything from your mood to your ability to detoxify. Tune in to discover: The 'sticky note' analogy that makes understanding methylation a breeze Why poor methylation could be behind your unexplained fatigue, brain fog, or mood swings The shocking connection between methylation and your risk of heart disease and autoimmune disorders Nature's top methylation boosters - including one surprising food that outperforms all others How your gut health might be the secret key to optimizing your methylation pathway The MTHFR gene variant: what it means and why you should care Simple, actionable steps to support your body's methylation process starting today Whether you're a health enthusiast or struggling with unexplained symptoms, this episode is a must-listen. Dr. Axe delivers complex information in an easy-to-understand format, equipping you with the knowledge to take control of your health. By the end of this show, you'll have a clear understanding of methylation and a practical toolkit to optimize this vital process in your body. Don't miss out on this game-changing information - your cells will thank you! Want more of The Dr. Josh Axe Show? Subscribe to the YouTube channel. Follow Dr. Josh Axe Instagram Twitter Facebook Tik-Tok ------  Links:  Ferira, L. (2021). "The Role of Methylation in Human Health." Journal of Nutrition. Rountree, R. (2020). "Environmental Impacts on Methylation." Environmental Health Perspectives. Masterjohn, C. (2022). "Riboflavin and Its Importance for Methylation." Nutritional Biochemistry. CDC (2023). "Antibiotic Resistance and Usage Statistics." WHO (2022). "COVID-19 and Antibiotic Usage." Smith, A. D., & Refsum, H. (2016). "Homocysteine, B Vitamins, and Cognitive Impairment." Annual Review of Nutrition. Watanabe, F., & Yabuta, Y. (2013). "Vitamin B12 Sources and Bioavailability." Food and Nutrition Bulletin. Bailey, L. B., & Gregory, J. F. (2011). "Folate and Other Methyl Donors: Effects on the Risk of Cardiovascular Disease." Current Opinion in Lipidology. Pinna, K. L. (2018). "Probiotics and Gut Health: Mechanisms and Applications." Frontiers in Microbiology. Ulta Labs. (2023). "MTHFR Gene Variation Testing and Homocysteine Testing."

The Autoimmune RESET
FRIDAY 5 - Markers Of Inflammation You Don't Want To Miss If You Have Autoimmune Disease

The Autoimmune RESET

Play Episode Listen Later Jun 14, 2024 18:33


Send us a Text Message.In this FRIDAY 5 episode of "The Autoimmune RESET," VJ Hamilton explores key markers of inflammation from a functional medicine perspective. VJ dives into the roles of C-Reactive Protein (CRP), Erythrocyte Sedimentation Rate (ESR), Tumor Necrosis Factor-alpha (TNF-alpha), Interleukin-6 (IL-6), and Homocysteine in indicating both acute and chronic inflammation. VJ explains how genetic variations in IL-6 and TNF-alpha can predispose individuals to higher inflammation levels and discusses the importance of tracking symptoms even when these markers are normal. VJ also cover how localized inflammation, such as in the gut, can be detected using calprotectin. Learn how understanding these markers can provide a comprehensive view of your health and guide effective holistic management strategies. Tune in for valuable insights into maintaining a balanced lifestyle and reducing inflammation naturally.If you would like to book a free initial consultation with VJ Hamilton, The Autoimmunity Nutritionist, to find out about allergy testing and how nutritional therapy and functional testing could improve your health, you can book an appointment here.Learn more about the functional medicine services at The Autoimmunity Nutritionist Clinic here.Thanks for listening! You can join The Autoimmune Forum on Facebook or find me on Instagram @theautoimmunitynutritionist.

Zestology: Live with energy, vitality and motivation
Review: Homocysteine Fingerprick Testing and Microdosing Ozempic!? #496

Zestology: Live with energy, vitality and motivation

Play Episode Listen Later Jun 6, 2024 9:36


At-home testing is so important on your health journey. So today we're looking at emerging options for heart and health testing, plus whether ozempic could ever be a positive for biohackers. This is a Biohacking Reviews episode, where we review; products, supplements, health tech, practices... whatever is new and whatever we've been trying.  My guest is one of the world's top micro-surgeons and human optimisation experts and is the founder of Hum2n clinic in London, Dr Mohammed Enayat Join 30k+ weekly biohackers who receive the latest tech + techniques + reviews + insider biohacking news by signing up for the weekly newsletter here.

Just Ingredients
153 - Uncovering Hidden Illnesses: What Blood Tests Can Reveal w/ Dr. Mary Pardee

Just Ingredients

Play Episode Listen Later Jun 3, 2024 59:23


In today's episode, Dr. Pardee and I discuss all things related to blood work and the importance of various tests for our overall health. Dr. Pardee emphasizes the significance of blood work as a window into our body's internal health. While external symptoms may be noticeable, blood work can reveal underlying issues that may not have any visible signs. Tests like the Comprehensive Metabolic Panel and Lipid Panel are crucial in detecting early signs of diseases like heart disease and diabetes. She then sheds some light on homocysteine. Homocysteine levels can provide valuable insights into our body's methylation cycle and potential deficiencies in essential vitamins and cofactors. Elevated homocysteine levels have been associated with increased risks of cardiovascular diseases and cognitive impairment. Testing homocysteine and addressing any imbalances can help reduce these risks. If you've ever been curious about what your blood work results mean or why certain tests are important, this episode is a must-listen! Dr. Pardee's Instagram: https://www.instagram.com/dr.marypardee/?hl=en Modrn Med Instagram: https://www.instagram.com/modrnmed/ Dr. Pardee's Website: https://www.modrnmed.com/ For 30% off at Truly Free Use Code JUSTINGREDIENTS at https://trulyfreehome.com/ Want more Just Ingredients content: https://www.instagram.com/stories/just.ingredients/3277567597818090802/ https://www.instagram.com/just.ingredients.podcast/ https://www.facebook.com/groups/2433401933539581/ Find our non-toxic product line here: https://justingredients.us/

I'd Love to Know
Prevention of Cardiovascular Disease: Donald Lloyd-Jones, MD

I'd Love to Know

Play Episode Listen Later May 31, 2024 79:54


Focusing on cardiovascular health is essential in aging. On today's episode, we dive deep with Donald Lloyd-Jones, MD, to discuss cardiovascular disease risk factors, learn different biomarkers and their ideal target levels, understand the role of screening tests, and Dr. Lloyd-Jones' essential tips for preventing cardiovascular disease.Donald Lloyd-Jones, MD, is a world-class cardiologist and epidemiologist who recently served as president of the American Heart Association. His research interests include cardiovascular health and healthy aging, and cardiovascular disease epidemiology and prevention. He has served on the faculty and in leadership roles at Harvard Medical School and Northwestern. He received his MD from Columbia University College of Physicians and Surgeons and his master's in epidemiology from the Harvard School of Public Health.(03:17) – Introducing Dr. Don Lloyd Jones(06:01) – Looking at evidence(08:34) – The demographics of cardiovascular disease(11:30) – Causal risk factors(13:29) – Creating longer-term risk estimates(17:00) – Cumulative risk(21:10) – Addressing risk at a younger age(23:31) – Monitoring blood pressure(29:00) – Sodium(32:03) – Cholesterol(36:27) – Screening for plaque(42:51) – Coronary calcium scores(44:49) – Total cholesterol numbers(51:39) – Apolipoprotein(a)(56:00) – Screening children(59:14) – Homocysteine levels(1:00:25) – Exercise (1:04:25) – Heart rate variability(1:05:40) – Hormone replacement therapy for women(1:08:05) – THC (1:10:40) – Microplastics(1:13:15) – COVID-19's impact on cardiovascular diseaseIf there are topics that you are interested in learning more about, please visit MichaelJLeeMD.com.If you'd like to receive new episodes as they're published, please follow I'd Love to Know in Apple Podcasts, Spotify, or wherever you get your podcasts. If you enjoyed this episode, please consider leaving a review on Apple Podcasts or Spotify. It really helps others find the show.The information from this podcast does not constitute medical advice and is meant for basic informational purposes only. If you're interested in pursuing any of the therapies, supplements, or medications discussed here, please consult with your physician.Podcast episode production by Dante32.

Vitality Radio Podcast with Jared St. Clair
#417: The B Vitamins: Understanding Their Roles and What They Can Do For You

Vitality Radio Podcast with Jared St. Clair

Play Episode Listen Later Mar 30, 2024 55:51


It's a pretty common understanding that B vitamins are an important nutrient we all need, but do you ever wonder what each B vitamin does for you? Do you wonder which one you should take or if you should be taking a B-Complex? On this episode of Vitality Radio, Jared explains the role of each of the B vitamins and answers those questions. You'll learn about methylation, MTHFR, and why the form of your B vitamins matter and also about a very specific B vitamin almost nobody knows about! Products MentionedAdditional Information:#329: MTHFR Mutations, Methylated B Vitamins, Folic Acid vs. Methylfolate and more with Carrie Pattison#346: The Ultimate Vitality Multi - What Makes It the Ultimate Multivitamin for YouBe Healthy UtahBe Healthy Utah discount code: vitality40Visit the podcast website here: VitalityRadio.comYou can follow @vitalityradio and @vitalitynutritionbountiful on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Please also join us on the Dearly Discarded Podcast with Jared St. Clair.Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

Vitality Radio Podcast with Jared St. Clair
#395: How Aged Garlic Extract Benefits Every System In Your Body with Dr. Jim LaValle

Vitality Radio Podcast with Jared St. Clair

Play Episode Listen Later Jan 13, 2024 55:51


What is Aged Garlic Extract (A.G.E.) and how is it different from the garlic we eat? Can this one thing actually lower cholesterol, improve insulin resistance, keep bones strong, boost immunity and detoxification, and prevent dementia? We tend to compartmentalize our bodily systems, but they are all connected and the cardiovascular system is at the head of them all. Learn the science behind how A.G.E. can impact all of our systems, how to take it, how much to take, and what the research actually shows, on this episode of Vitality Radio, where Jared interviews Dr. Jim LaValle all about Kyolic Aged Garlic Extract. You'll learn its many benefits and how to use it to improve your overall health. Dr. Jim LaValle is an internationally recognized clinical pharmacist, author, and board-certified clinical nutritionist, with over 40 years of clinical experience. He is considered a renowned expert in his field.Products:Kyolic Aged Garlic ProductsAdditional Information:#278: The Incredible Benefits of Aged Garlic ExtractLipid tests discussed: NMR LipoProfile® TestCardio IQ®Visit the podcast website here: VitalityRadio.comYou can follow @vitalityradio and @vitalitynutritionbountiful on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Please also join us on the Dearly Discarded Podcast with Jared St. Clair.Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

Sigma Nutrition Radio
Listener Q&A: Homocysteine, MUFA, Healhty BMI, and more! (Preview)

Sigma Nutrition Radio

Play Episode Listen Later Dec 26, 2023 19:55 Very Popular


This episode is one of our Premium-exclusive AMA (ask me anything) episodes, where we answer questions submitted by Premium subscribers. To listen to the full 90 minute episode, you'll need to be a Premium subscriber and access the episode on the private Premium feed. Otherwise, you can hear a preview of the episode here. Full List of Questions: [01:50] How should one interpret the systematic reviews done by Hooper et al that report no association between modification or reduction of saturated fat intake with cardiovascular mortality, total mortality, non-fatal MI? [22.10] Given most people don't meet them, are public health targets for fruit and vegetables too high? [29.10] What is the role of homocysteine in heart disese? Is it causal? [40:45] Monounsaturated Fat: Good, Bad or Indifferent? [50:13] Is there evidence to suggest an upper limit for BMI, where even individuals with a ‘healthy' body composition would be at elevated risk? [59:32] Where does the current research stand on the impact of diet on brain health? [01:08:48] Based on recent findings, do we have to throw out previous research on diet's impact on the gut microbiome?