Podcasts about Bartonella

Dr. Pamela Cipriano shares her journey from being an ICU nurse to a trailblazer in functional medicine. She discusses her personal experiences with Lyme disease, the importance of hydration, nutrition, and the impact of chronic illnesses. Dr. Cipriano emphasizes the need for a holistic approach to health, focusing on root causes and lifestyle changes, while also sharing insights on the effects of COVID and the importance of proper diet and hydration. In this conversation, Dr. Pamela Cipriano discusses the implications of vaccination, particularly in relation to health concerns and the effects of spike proteins. She emphasizes the importance of Vitamin B12 and mitochondrial function in overall health, while also addressing oxidative stress and innovative therapies for chronic conditions. The discussion extends to the future of Lyme disease treatment and the challenges in diagnosing and treating Bartonella, highlighting the need for proper education and awareness in managing tick-borne diseases.   For Audience Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now   Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!      Takeaways   ·       Dr. Cipriano transitioned from nursing to functional medicine to help patients achieve better health. ·       Her personal experience with her son's Lyme disease shaped her focus on chronic illnesses. ·       Chronic diseases often have triggers that can be identified and addressed. ·       Water intake is crucial for overall health and disease prevention. ·       Nutrition plays a significant role in managing inflammation and chronic diseases. ·       Avoiding processed foods and sugars is essential for maintaining health. ·       The quality of food, including meat and dairy, impacts health outcomes. ·       Functional medicine requires a thorough understanding of a patient's history and lifestyle. ·       COVID-19 has highlighted the importance of diet and hydration in recovery. ·       The healthcare system often prioritizes medication over holistic health solutions. Vaccination can lead to health problems in some individuals. ·       Spike proteins may persist and cause long-term health issues. ·       Vitamin B12 is crucial for nervous system health. ·       Mitochondria play a vital role in cellular function and energy production. ·       Oxidative stress accelerates aging and cellular damage. ·       IV therapies can significantly aid in recovery from chronic conditions. ·       Bartonella can mimic severe neurological disorders like ALS. ·       Proper testing is essential for diagnosing tick-borne diseases. ·       Education is critical for effective treatment of Lyme disease. ·       Innovative therapies are emerging for chronic health issues.       Chapters 00:00 Introduction to Dr. Pamela Cipriano 01:32 Journey into Functional Medicine 02:52 Personal Experience with Lyme Disease 04:55 Understanding Chronic Illnesses 06:57 The Importance of Water and Hydration 13:43 Nutrition and Anti-Inflammatory Foods 19:28 Insights on COVID and Long COVID 20:26 The Impact of Vaccination and Health Concerns 21:53 Understanding Spike Proteins and Their Effects 22:38 The Importance of Vitamin B12 23:54 Mitochondrial Function and Health 25:53 Oxidative Stress and Its Management 27:45 Innovative Therapies for Chronic Conditions 30:37 The Future of Lyme Disease Treatment 32:55 Bartonella: Diagnosis and Treatment Challenges 39:56 Navigating Tick-Borne Diseases   To learn more about Dr. Pamela Cipriano: Facebook: https://www.facebook.com/Dr.Pamela.Cipriano Instagram: https://www.instagram.com/practicehealthwellness YouTube: https://www.youtube.com/@dr.pamelacipriano1329 Website: https://www.thepracticeofhealthandwellness.com   Reach out to us at:    Website: https://gladdenlongevity.com/     Facebook: https://www.facebook.com/Gladdenlongevity/    Instagram: https://www.instagram.com/gladdenlongevity/?hl=en     LinkedIn: https://www.linkedin.com/company/gladdenlongevity    YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw    

What happens when your body starts to heal, but your mind is still trapped in survival mode? In this episode of hol+, Dr. Taz sits down with Amy Kurtz, certified health coach, patient advocate, speaker, and author "But You Look Fine", for a powerful conversation about chronic illness, Lyme disease, medical gaslighting, nervous system trauma, and what it really means to heal.Together, they explore Amy's 20+ year journey through unexplained pain, chronic symptoms, misdiagnosis, and the search for answers that finally led to a diagnosis of late-stage neurological Lyme disease and co-infections. Amy shares what it was like to be told her labs were normal while knowing something was deeply wrong in her body, and how years of invalidation shaped her relationship with her health, her identity, and her trust in herself.Dr. Taz and Amy also discuss why so many people live in the “gray zone” between sick and well, especially when symptoms are invisible, complex, or hard to explain. They unpack why normal labs do not always mean optimal health, why Lyme disease can be missed for years, and how chronic illness can impact relationships, career, emotional safety, and the nervous system.This conversation offers a grounded and hopeful look at what happens after illness, when the body may be improving but the mind and nervous system are still bracing for the next crash. Amy introduces her concept of Medical Trauma Brain, or MTB, which describes the anxiety, hypervigilance, fear, and survival patterns that can remain after chronic illness, cancer, stroke, chronic pain, or any major health crisis.If you're listening to this and thinking, “I know something is off in my body, but I don't know where to start,” join the Circle here:

What if your body already has everything it needs to heal and unresolved trauma is the only thing standing in the way?In this episode of What Happens in Vagus, Dr. Stephanie Canestraro sits down with Peter McLaughlin, a certified hypnotherapist who put his chronic lymphocytic leukemia into remission in 2003, without chemotherapy. Peter's journey began in the wreckage of a life running on pure adrenaline: a demanding Wall Street career, a two-hour daily commute, three young children, and an office one block from Ground Zero on September 11th. When his body finally gave out, his leukemia diagnosis became the catalyst that set him on a path toward subconscious healing, hypnotherapy, and a complete understanding of the mind-body connection.Together, Peter and Dr. Stephanie explore one of the most overlooked truths in chronic illness: that emotional trauma, including small, seemingly insignificant moments from childhood, gets stored in the subconscious mind and continues to drive the body's stress response for decades. Because the subconscious has no concept of time, a humiliating moment in third grade or a cry left unanswered in a crib can still be activating a fight-or-flight response in your body today. This chronic activation of the autonomic nervous system suppresses immunity, disrupts hormones, stalls digestion, and creates the environment in which disease takes root.Dr. Stephanie also shares her own healing journey from a Lyme disease and Bartonella infection that attacked her nervous system and went undiagnosed for over a decade, to the functional medicine interventions, precious metal IVs, and reconnection with her body's inner wisdom that finally brought her back. Together they connect the dots between nervous system dysregulation, frequency medicine, and the extraordinary capacity of the human body to heal when given the right tools.✦ In this episode:• How chronic stress and emotional trauma directly contribute to serious illness• Why childhood events your conscious mind has "forgotten" are still running your nervous system• What hypnotherapy actually does and how it clears emotional toxins from the subconscious• Why you cannot heal in fight-or-flight mode and how to shift into rest-and-digest• How cortisol signals your body to hold onto fat• 432 Hz healing music, binaural beats, and frequencies that regulate the nervous system• Applied kinesiology, muscle testing, and pendulum work as tools for inner wisdom• Peter's work with professional athletes and how childhood trauma shows up on the field• Precious metals (gold, silver, platinum) and their role in healing chronic infection• The placebo effect as proof of the mind's power to heal the body✦ Find Peter McLaughlin:Website & healing tracks: blueskyhypnosis.comYouTube: @blueskyhypnosis✦ About Dr. Stephanie Canestraro:Dr. Stephanie is a chiropractor, functional medicine practitioner, and chronic illness survivor. Her practice and this podcast are rooted in one belief: that the body is designed to heal, and that the vagus nerve is the master key to making that happen.Let us know your thoughts on this episode hereFor any further information, feel free to email us at info@vagusclinic.com.  Our team is happy to help.  We offer 20-minute complimentary health calls, and you can sign up for one here.

This is episode 83 of the Love, Hope, Lyme podcast. This podcast does not replace medical care. If you're struggling with Lyme symptoms, please seek proper medical care. The pdf of Love, Hope, Lyme: What Family Members, Partners, and Friends Who Love a Chronic Lyme Survivors Need to Know is always free for chronic Lyme survivors. Reach out to Fred Diamond on social media for your copy.

In this episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden speaks with Nicole Bell and Jennifer Miller from Galaxy Diagnostics about the challenges and advancements in diagnosing and treating tick-borne illnesses, particularly Lyme disease. They discuss the personal journey that led Nicole to become the CEO of Galaxy Diagnostics, the complexities of the immune response to Lyme, and the innovative diagnostic approaches being developed to improve patient outcomes. The conversation also touches on the implications of co-infections and the future of research in this critical area of health.   For Audience Join the other 20,000+ high-performers getting weekly insights on biological reversal, exponential strategies, and Life Energy optimization→ https://start.gladdenlongevity.com/subscribe If you're ready to measure your 60+ biological ages and build a personalized reversal plan, apply for a discovery call here → https://start.gladdenlongevity.com/apply-now   Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/!      Takeaways ·       Nicole Bell's personal experience with tick-borne illness led her to Galaxy Diagnostics. ·       Lyme disease can be misdiagnosed, leading to severe consequences. ·       The immune response to Lyme is complex and can lead to chronic inflammation. ·       Genetic predispositions can affect how individuals respond to tick-borne pathogens. ·       Innovative diagnostic methods are being developed to improve detection of Lyme and co-infections. ·       Urine samples can be effective for diagnosing Lyme disease. ·       Co-infections like Bartonella can complicate treatment and diagnosis. ·       Early diagnosis is crucial for effective treatment of tick-borne illnesses. ·       Research is ongoing to better understand the relationship between tick-borne pathogens and mental health. ·       Galaxy Diagnostics aims to change the standard of care for tick-borne illnesses.     Chapters 00:00 Introduction to Tick-Borne Illnesses 05:04 The Journey of Diagnosis and Treatment 09:50 Understanding Lyme Disease and Its Challenges 14:53 The Immune Response and Genetic Factors 19:54 Innovative Diagnostic Approaches 24:53 Co-Infections and Their Implications 29:55 The Future of Tick-Borne Pathogen Research   To learn more about Nicole Bell/Galaxy Diagnostics:Email: nicole.bell@galaxydx.com Website: https://www.galaxydx.com/   Reach out to us at:    Website: https://gladdenlongevity.com/     Facebook: https://www.facebook.com/Gladdenlongevity/    Instagram: https://www.instagram.com/gladdenlongevity/?hl=en     LinkedIn: https://www.linkedin.com/company/gladdenlongevity    YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw       Gladden Longevity Podcast Disclosures Production & Independence The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas. Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements. Medical Disclaimer The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content. The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options. Use of information from this podcast and any linked materials is at the listener's own risk. Podcast Guest Disclosures Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team. Sponsorships & Affiliate Disclosures To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes. We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented. Additional Note on Content Integrity All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.

Are you doing everything "right"… but still feeling exhausted, inflamed, or stuck? In this episode of The Coach Debbie Potts Show, I sit down with Brad Pitzele, founder of One Thousand Roads, to explore one of the most overlooked drivers of energy, recovery, and resilience: Oxygen at the cellular level. After facing autoimmune arthritis, malignant melanoma, Lyme disease, and Bartonella, Brad found himself searching beyond conventional approaches when his health continued to decline. What he discovered is something many high performers—and especially midlife athletes—often miss: Your body cannot produce energy, repair tissue, or recover effectively without proper oxygen delivery and utilization. In this conversation, we break down the science and real-world application of Exercise With Oxygen Therapy (EWOT) and red light therapy, and how these tools can help improve mitochondrial function, reduce inflammation, and restore energy. We also explore how poor oxygen utilization may be contributing to fatigue, brain fog, slow recovery, and metabolic dysfunction—even when you're training, eating well, and doing all the "right" things. In this episode, you will learn: What Exercise With Oxygen Therapy (EWOT) is and how it works The connection between oxygen, mitochondria, and ATP production Why fatigue and brain fog may be linked to poor oxygen utilization How red light therapy supports cellular energy and recovery The concept of an "oxygen deficit" and its role in chronic inflammation How oxygen supports detoxification through the lungs and movement Why high performers often get stuck in a "survival mode" state Practical ways to begin improving oxygen delivery and recovery capacity Free Resource from Brad Pitzele: The Synergistic Power of EWOT & Red Light Therapy www.bradtalkshealth.com https://www.onethousandroads.com/pages/podcast Connect with Brad: Website: One Thousand Roads Instagram: @onethousandroadshq If this episode resonates with you and you are ready to stop guessing and start testing your metabolism, energy systems, and recovery capacity: Schedule your Discovery Call at: www.debbiepotts.net The Coach Debbie Potts Show is designed for high-performing individuals in midlife who want to improve metabolism, build strength, restore energy, and optimize longevity by addressing the root cause—not just the symptoms.

In this episode of Resiliency Radio with Dr. Jill, Dr. Jill Carnahan welcomes Dr. Richard Horowitz, one of the world's leading experts in chronic illness and tick-borne disease, to discuss the groundbreaking science behind the MSIDS model and its implications for conditions ranging from Lyme disease to Alzheimer's. Dr. Horowitz shares revolutionary findings connecting chronic infections, inflammation, environmental toxins, gut dysfunction, and immune imbalance to persistent disease. He also discusses a surprising breakthrough involving Alzheimer's biomarkers and chronic Lyme treatment using his innovative dapsone protocol. This powerful conversation explores how addressing the root causes of inflammation and chronic illness may transform the future of medicine and offer hope for patients struggling with complex, unresolved health conditions.

After a serious heart attack with no conventional warning signs, Dr. John Kim went searching for answers. He was shocked to find what conventional testing never unearthed: he was unknowingly fighting a Bartonella infection, a heavy mycotoxin load and parasites. This was when the pharmacist turned functional medicine practitioner learned the role cellular energy plays in health breakdowns, and, vitally, in healing.  In this episode, you'll learn about cell-danger response and the connection between biotoxins and mitochondrial dysfunction (did you know if your cells are healthy they repel parasites?!). Dr. Kim shares his best tips for cellular healing (butyrate, phospholipids and sunlight) and walks us through the steps he takes his own clients through: taking stock of your individual environment, healing your nervous system, detox pathways, strengthening the microbiome, and building resilience so you can live your life. Chapters 2:54 Dr. John Kim's Heart Attack Story 4:11 His Struggle with Biotoxins 9:11 Cell Danger Response 11:00 The Impact of Mitochondrial Dysfunction 14:01 Mold Toxicity and Its Effects 19:49 Detoxification Strategies and Methodologies 24:00 The Encore Method for Healing 29:02 The Importance of Circadian Rhythms 32:15 Harnessing Sunlight for Cellular Health 36:09 Optimizing Cellular Function and Detoxification 45:30 Creating Cellular Resiliency 47:03 The Role of Emotional Health in Detoxification 49:22 A Simple Exercise to Increase HRV ------  Follow Doctor Motley! Instagram TikTok Facebook Website Connect with Dr. John Kim: https://www.drjohnkim.com/ https://www.instagram.com/john.pharmd/ ------  * Are you looking for simple, non-invasive sound therapy tools for treating anxiety, or providing balance? You can get $100 off a WAVwatch with the code DRMOTLEY: https://wavwatch.com/pages/doctor-motley *Join Doctor Motley's newsletter for TCM insights and regular podcast updates: https://www.doctormotley.com/ *Do you have a ton more in-depth questions for Doctor Motley? Check out his course on emotions and the body in his membership. You'll find other courses full of his expertise and clinical wisdom, plus bring all your questions to his weekly lives! To try risk-free for 15 days click here: https://www.doctormotley.com/15

The last time I spoke to Shannon LaDeau at the Cary Institute of Ecosystem Studies, in February, we were in the middle of our first classically cold winter in several years, thanks to a wonky polar vortex. I asked Shannon if all the deep freezes might lead to a down year for ticks and tick-borne illnesses. She reminded me that blacklegged ticks, the buggers responsible for Lyme disease, are well-adapted to cold weather. However, to pass pathogens to us, the ticks must feed on an infected animal, typically a deer or a white-footed mouse. If the brutal cold affected them, we could frolic with less concern. Unfortunately, it appears we will not have a carefree tick season. LaDeau and her colleagues are starting their annual tick counts in Millbrook, and there isn't any hard data yet on the deer and mice populations, but "the ticks so far do not seem to be showing any signs of suffering from winter effects," she said last week. The federal Centers for Disease Control and Prevention says that emergency room visits for tick bites are three times what was reported at the same time last year. That's especially bad news considering a report that LaDeau and the Cary Institute just put out with researchers at SUNY Albany: Ticks in the Hudson Valley are becoming more likely to carry more than one pathogen, increasing the chances that you could get multiple diseases from just a single bite. The Cary Institute has been studying ticks for more than 30 years. It has decades of data and ticks placed in cold storage in anticipation of additional funding and improved technology. For the recent study, the researchers screened 10 years' worth of nymphal blacklegged ticks — the poppy-seed ones that are so difficult to detect — for 16 pathogens. They found that about 10 percent were carrying more than one pathogen, but that the rate had increased over the years. The most prevalent pathogens were those that cause Lyme disease and babesiosis, a malaria-like disease that can be devastating for some but has little effect on others. (I found out seven years ago that I had it only because it came up in a test when I gave blood.) If there's good news, it's that diseases such as the Powassan virus, which can cause brain inflammation and meningitis, only showed up in a single tick, and the bacteria (Bartonella henselae) that cause "cat scratch disease" didn't show up at all. The researchers also didn't find any ticks with alpha-gal, a molecule that can cause allergic reactions to red meat. That's not surprising, because lone star ticks are most likely to cause alpha-gal syndrome. While they have been found on Long Island, they are not prevalent in the Hudson Valley and haven't been found at Cary. But the researchers did find a few ticks carrying pathogens responsible for Rocky Mountain Spotted Fever, which usually isn't found in blacklegged ticks. What's causing these changes? It's not clear, but LaDeau has some hypotheses. If nymphs carry more than one pathogen, it's likely they picked them up from the animal they bit, because they're probably too young to have had multiple meals. That would suggest deer and white-footed mice can also carry multiple pathogens, possibly from having been bitten repeatedly over years. Contracting one pathogen might also make hosts more vulnerable to infection from a different pathogen. "There are some lab studies that suggest that that's possible," said LaDeau. If you find a tick has been feasting on you for at least 12 hours, get tested for multiple infections. LaDeau worries that the prevalence of Lyme disease in the Hudson Valley has made doctors less likely to test for other infections or to start patients right away on an antibiotic such as doxycycline, which is not the best strategy for other infections. For instance, treating babesiosis requires anti-malarial drugs. It's also worth noting that Pfizer recently announced that its Lyme vaccine, which has completed Phase 3 trials, is 70 percent effective and has no repo...

What happens when your country's medical system refuses to believe you have the disease that's destroying your life? In this episode of Integrative Lyme Solutions, Dr. K sits down with Lachlan Onegin-Ward, a marine biologist and wildlife conservationist from Australia who contracted Lyme disease after being bitten by 17 ticks on a snake-spotting trip south of Sydney. What followed was a years-long battle not just against Bartonella, Rickettsia, and Babesia — but against a medical system that handed him antacids instead of answers. Lachlan shares the raw reality of fighting Lyme disease in a country that officially denies its existence, navigating a healthcare system that left him bedridden, seizing, and unable to move his arms — all while spending tens of thousands of dollars chasing a diagnosis. He opens up about the neurological relapse triggered by COVID, the PTSD of living with an invisible illness, losing close friends who couldn't understand what they couldn't see, and the grassroots mission he's now on to make sure no other Australian has to go through this alone. Key Takeaways: 0:00 Introduction  3:00 17 tick bites, one wildlife trip  8:10 Australia's medical system denies Lyme exists  13:20 Triple co-infection: Bartonella, Rickettsia, and Babesia  18:00 COVID triggers seizures after 11 seizure-free years  25:00 The financial toll of chasing treatment in Australia  30:30 Podcasting to fill the awareness gap  34:00 Invisible illness and the friends who disappeared  Schedule a Free 15-Min Phone Lyme Consultation at The Karlfeldt Center: 208-338-8902 Resources: Lyme Disease Association of Australia - https://www.lymedisease.org.au/ Tick Science Alliance - https://ticksciencealliance.au/ IGENEX - https://igenex.com/ Let's Get Aussie Wild / Corona and Lyme Podcast (Spotify) - https://open.spotify.com/show/0xRfQ3zKvuivkgtBEiFuxf Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions. ____________________________________WORK WITH DR. KARLFELDT:The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies available. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor, contact us at:

Your cells are starving for oxygen, and it's silently driving inflammation, fatigue, brain fog, and accelerated aging. This episode reveals how pairing Exercise with Oxygen Therapy (EWOT) and red light therapy supercharges your mitochondria, reverses pseudo-hypoxia, and unlocks a level of human performance most people never experience. -Save up to $500 (through 5/17) at One Thousand Roads: https://www.onethousandroads.com/Dave -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Brad Pitzele, founder of One Thousand Roads and one of the most credible voices in oxygen therapy and red light therapy. Brad didn't come to this work through a lab. He came to it through desperation. After battling autoimmune arthritis, melanoma, and Lyme disease, he rebuilt his health from the ground up starting in 2016 by targeting mitochondrial function when he could barely walk. Eighteen months later, he founded One Thousand Roads to bring these tools to everyone still searching for a way out. Together, Dave and Brad break down the unified theory behind oxygen therapy and red light therapy, two of the most powerful and underrated tools in biohacking. They go deep on pseudo-hypoxia, the condition where your blood oxygen looks fine but your tissues are starving, and explain why this hidden dysfunction sits at the root of chronic fatigue, inflammaging, fibromyalgia, long COVID, and poor sleep optimization. They also cover the endothelium, nitric oxide, arterial stiffness, pulse wave velocity, and why your morning biology might be the most honest readout of your metabolic health. This is essential listening for anyone serious about longevity, anti-aging, brain optimization, functional medicine, mitochondria, metabolism, and smarter not harder approaches to human performance. You'll Learn: What EWOT is and why elite athletes and biohackers use it to flood tissues with oxygen in 15 minutes How pseudo-hypoxia silently blocks energy production and drives chronic illness Why stacking red light therapy immediately after EWOT multiplies results for both How mitochondrial dysfunction connects to endothelial aging, microcirculation failure, and systemic inflammation The role of nitric oxide in arterial flexibility, vasodilation, and real anti-aging markers like pulse wave velocity Why your lungs are your biggest detox organ and how oxygen therapy supports that process How ketosis, fasting, and cellular energy interact with EWOT and red light for maximum benefit What LED lighting is doing to your mitochondria every single day and how to fix it How to build an affordable at-home EWOT setup for around $2,500 Thank you to our sponsors! - Danger Coffee | Grab yours at DangerCoffee.comand use code DAVEPOD at checkout for 15% off. - ENERGYbits | If you want a simpler, smarter way to support your body… this is it. Head to ENERGYbits.com and use code ASPREY for 20% off your order. - Suppgrade Labs | Grab your DAKE and Minerals 101 duo at shopsuppgradelabs.com and use code DAVEPOD for 15% off today - Cowboy Colostrum | Get your gut right by going to cowboycolostrum.com/asprey for 25% off of your entire order. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Brad Pitzele, One Thousand Roads, EWOT, exercise with oxygen therapy, oxygen therapy, red light therapy, infrared light therapy, pseudo-hypoxia, mitochondria, mitochondrial dysfunction, biohacking, longevity, anti-aging, human performance, inflammation, inflammaging, microcirculation, endothelium, glycocalyx, nitric oxide, arterial stiffness, pulse wave velocity, capillary health, cellular energy, ATP production, aerobic respiration, anaerobic respiration, VO2 max, chronic fatigue, fibromyalgia, brain fog, autoimmune disease, Lyme disease, Bartonella, long COVID, mast cell activation, detoxification, lung health, sleep optimization, metabolism, functional medicine, ketosis, fasting, red light bulbs, LED lighting, light therapy, wavelengths, near infrared, oxygen concentrator Resources: • Save up to $500 (through 5/17) at One Thousand Roads: https://www.onethousandroads.com/Dave • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 01:41 – Welcome Brad 03:01 – What Is EWOT? 05:27 – EWOT vs. Hospital Oxygen 06:51 – Longevity & Inflammaging 11:42 – Pseudo-Hypoxia 12:57 – Red Light Therapy 15:47 – EWOT + Red Light Unified Theory 18:00 – Nutrition, Ketosis & VO2 Max 19:56 – Stacking EWOT & Red Light 22:01 – Equipment & Cost 26:00 – Junk Light & LED Problems 30:51 – Sunlight & Nitric Oxide 32:36 – Endothelium & Microcirculation 38:49 – Arterial Stiffness & Pulse Wave Velocity 43:29 – Lungs as a Detox Organ 45:04 – EWOT for Long COVID 47:58 – Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode, Cheryl sits down with Brad Pitzele to unpack a long and complicated health journey that began with early autoimmune symptoms and escalated into psoriatic arthritis, debilitating fatigue, and eventually melanoma linked to immunosuppressive treatment. Frustrated by a system that offered only escalating medications and limited answers, Brad began an intense period of self-experimentation and research. His turning point came after a Lyme disease diagnosis, one that helped connect years of seemingly unrelated symptoms. This ultimately pushed him deeper into understanding the root causes of chronic illness, especially the role of mitochondrial dysfunction and inflammation. From there, the conversation shifts into the tools that helped Brad reclaim his health, including exercise with oxygen therapy (EWOT) and red and near-infrared light therapy. He explains how both approaches work at a cellular level to improve oxygen delivery, support mitochondrial function, and reduce inflammation. Thseare are all mechanisms that have implications for conditions like chronic fatigue, autoimmune disease, multiple sclerosis and even cardiovascular health. This episode is a deep dive into resilience, curiosity, and the power of continuing to search for answers when conventional paths fall short, offering both practical insight and hope for anyone navigating complex or unexplained health challenges. Connect with Brad at One Thousand Roads. Disclaimer: Links may contain affiliate links, which means we may get paid a commission at no additional cost to you if you purchase through this page. Read our full disclosure here. Takeaways Chronic symptoms do not always have clear answers and standard care often focuses on managing symptoms rather than addressing root causes Mitochondrial health plays a central role in energy, recovery, and overall resilience and when it is compromised nearly every system in the body is affected Inflammation and low oxygen levels go hand in hand, creating a cycle that can worsen chronic illness over time Exercise with oxygen therapy works by increasing oxygen delivery to tissues and may support energy production and reduce inflammation Red and near infrared light therapy may enhance mitochondrial function by increasing cellular demand for oxygen and boosting energy output Combining oxygen therapy with red light can create a complementary supply and demand effect at the cellular level Healing from complex or chronic conditions is rarely quick and consistent cumulative inputs over time matter more than short term fixes Self advocacy and curiosity are critical when navigating unexplained health issues or when conventional approaches fall short Small improvements over time can rebuild momentum and hope even before full recovery is achieved Simple inputs like oxygen, light, and movement can have powerful effects when applied consistently and strategically Watch on YouTube Disclaimer: Links may contain affiliate links, which means we may get paid a commission at no additional cost to you if you purchase through this page. Read our full disclosure here. CONNECT WITH CHERYL Shop all my healthy lifestyle favorites, lots of discounts!  21 Day Fat Loss Kickstart: Make Keto Easy, Take Diet Breaks and Still Lose Weight  Avaline Wines, Tested and Clean, Sugar Free Drinking Ketones Wild Pastures, Clean Meat to Your Doorstep 20% off for life  Clean Beauty 20% off first order DIY Lashes 10% off  NIRA at Home Laser for Wrinkles 10% off or current promo with code HealNourishGrow Instagram for daily stories with recipes, what I eat in a day and what’s going on in life Facebook YouTube  Pinterest TikTok Amazon Store The Shoe Fairy Competition Gear Getting Started with Keto Resources The Complete Beginners Guide to Keto Getting Started with Keto Podcast Episode Getting Started with Keto Resource Guide Episode Transcript Cheryl McColgan (00:00)Hey everyone, I’m Cheryl McColgan and today I am joined by Brad Pitzley and we are going to talk about some of his health history. He has a really interesting background with some challenging diseases and scenarios that he went through. And you know, like many of the guests on the HealNursery podcast, he just has a health journey that he wants to share with people and kind of what ended up actually helping him. Because so often people go down these roads with different conditions and they just have a lot of trouble finding out number one what it is, number two if there’s anything that can help them feel better or how to treat it. And so I think Brad’s going to have a lot of really interesting things to share with us today. So Brad, if you could just maybe start by, I don’t know how far in the way back machine you want to go, but kind of just, you know, give us a little bit about your health journey. And as we go along, I’m sure I’ll have some kind of questions to fill in for everyone. Brad Pitzele (00:50)Yeah, I had weird health things going on since grade school. I was diagnosed with psoriasis, but then I had other weird things that just kind of came and went. We’d go to the doctor, they’d give it a label. It would last for a while. There was no treatment for said label and then it would kind of just disappear and then I’d move on with life and then a year or six months or whatever, something else might pop up. But it really kind of started to come to a head. Um, probably around 2010 or 11, I started to develop autoimmune arthritis, what was considered psoriatic arthritis, which is, it’s basically like rheumatoid arthritis, but it’s what you get with psoriasis. Um, and they started to test all sorts of different drugs on me. The first sets didn’t work. Then they put me on, um, some immune suppressive drugs. They gave me relief for like maybe six months and they’d start wearing off and they would double the dose and they’re. I was kind of worse off when it wore off and then it would kind of bring me up a little bit. And then was kind of like I was taking a stair step into, you know, into a worse and worse place. And I was on those drugs for probably about two years. And then I developed melanoma. And that’s one of the side effects of the drugs is it’s got a high risk of cancer and specifically melanoma. So that was kind of a, a jumping off point for me. I, during that period, I also started to develop weird other symptoms. Like I started to get stiffness in the back of my legs. had tremendous brain fog and energy issues. had pain in my feet and I would take this back to the rheumatologist and I’d be like, this is, is this part of the, this disease? assume. he was like, no, that’s not part of the disease. And I was kind of shocked and like, well, it feels like part of the disease. It’s kind of, you know, it’s just. Cheryl McColgan (02:38)All right. Brad Pitzele (02:41)another symptom of whatever’s going on with me. But he didn’t really acknowledge that. And then when I got cancer, I went back to him and I was like, Hey, you know, I’m really afraid I’m like, if I keep taking these drugs, more risk of cancer. I don’t take these drugs. I, you know, I die, cripple crumpled up in a ball in the corner, so to speak. And he was kind of like, no, I don’t think that’s going to happen. Yeah. I think we’re just going to try another drug in the, the, the same category. And that was like, just started having alarm bells in my head. Just started shouting at me. was like, either path feels like it’s very bad. And I was a, I had a young children at the time. I was a relatively new father and that was even more scary. I was kind of the single income in the household. And I just started like, I’m like, what happens if these things happen to me to not just me, but my family. and that’s kind of when I started jumping off and like doing my own research and trying to figure out what I call a third path for because neither of those really made sense to me. Cheryl McColgan (03:40)those both sound like not very good options. I’m just kind of curious when you were going back to the doctor with these things, kind of two questions here actually. One, and I think I already know the answer, but one, were drugs the only answer that this doctor was able to give to you? And secondly, I think having the cancer being a known side effect of the drug is really interesting. you ever talk about what the mechanism there is or anything to know about that just for people with curiosity? Brad Pitzele (04:07)Yeah, so yeah, mostly it was drugs. He did also offer me injections of steroids into some of my joints. He was very skilled at it, because he said it was gonna be very painful. It wasn’t that painful, but steroids turn off your immune system. And it’s the same thing with some of the drugs I was on. One of them was a… I won’t call brand name, but it was a TNF inhibitor. TNF stands for tumor necrosis factor. And it’s basically in a component of our immune system. And so there was some research done and they found that if they turned off that component of your immune system, hey, the pain and symptoms go away. Unfortunately, as the name alludes to, it kills tumors. when you turn it, we all have cancer in our Cheryl McColgan (04:49)Yeah Brad Pitzele (04:52)body. Like right now as we speak, everyone has it. It’s just our immune system is able to kill it off and so it never really gains a foothold. But once you start tipping the balance of the scales, obviously, you know, it can run amok. And that’s what happened in my case. Cheryl McColgan (05:08)Yeah, very interesting. also it just brings up so many other questions that I’ll have to go down a rabbit hole after we’re done with our conversation. But so you had these things, you didn’t have good relief, you were still having symptoms, then you got cancer. And I assume obviously you had to get treated for that at that point. Was that really the turning point for you to just be like, I’ve got to find some other way to manage this? How did how did things go from there? Brad Pitzele (05:30)Yeah, it was, and I’m not gonna tell you it was a fast turn for me. It took me several years. But I mean, from there, I just started reading anything I could. I read books, I was out on the internet, I was in chat groups talking to other people who had similar symptoms, Facebook groups, Googling on PubMed, looking at research, so many rabbit holes I ran down. I was joking, I’m recovering engineer. ⁓ I got my undergraduate in mechanical engineering, so I’m very analytical by my nature, I suppose. Research didn’t scare me, and I just was reading anything I could. I wasn’t gonna… Cheryl McColgan (05:55)You Brad Pitzele (06:07)You know, wait for them to find something in the research and then try to translate it 20 years later. Like that does me no good. and I tried everything. I did a lot of self experimentation, everything from complete changes of diet, supplements, so many, mean, different modalities, all sorts of weird stuff. Sometimes my family looked at me pretty good side, I when they saw some of the stuff I was doing. but you know, when you’re, when you’re really desperate and. things are getting worse and worse. And particularly when you also feel this responsibility and obligation to your family, you just, it’s not even just about you. You’re like, what do I do? I like, I’m gonna disappoint all these people and life is not gonna be good for them. I just told myself, I’m not allowed. know, like this is absolutely not allowed. This is not gonna happen, but it kept happening for a few more years. And then, I ended up at a doctor’s office and he tried all sorts of things. Nothing was working. He was an MD, but he was non-insurance, so was integrative. And he was trying all sorts of alternate modalities on me. Even the things he was sure were gonna do anything, nothing was doing anything. He’s doing testing on me, nothing was popping. And then he suggested I do a Lyme disease test. I remember thinking, I’m like, doctor, I don’t have Lyme disease. I’m like, I’ve never been bitten by one of these ticks. I’ve never had that bullseye rash thing. I’m thinking to myself, I don’t have that. But I was kind of like, you know what? And it was expensive test at the time. It was like 500 bucks. Insurance didn’t pay. But I was like, you know what? I’m gonna pay the 500 bucks. I’m gonna do the test so he can see it’s negative and we can get him off this Lyme thing. We can get to the real deal because it’s not Lyme. And sure enough, it came back that I had Lyme disease and one of its co-infections called Bartonella, which is the infection that causes cat scratch disease as well. And I was so shocked. went back to him. was like, doc, what’s the chances this is a false positive? I don’t think I have it. And he was like, Brad, it’s a urine PCR, which means you have the DNA of those bacteria in your urine. What do you think is the chances it’s, it’s false positive? I’m like, got it. Cheryl McColgan (08:12)Not. Brad Pitzele (08:14)And that’s when it finally started to hit. ⁓ Cheryl McColgan (08:16)Well, just for people that aren’t familiar, I think everybody’s kind of heard of Lyme disease at some point, maybe Bartonella, but what did that kind of mean to you at the time? Like I’m sure once you got that diagnosis, you wanted to learn more about it. Were you thinking that that explained some of the things that you had up to this point or how did that mesh into the whole symptom profile? Brad Pitzele (08:36)Life disease is incredibly challenging. for a variety of reasons. One, it’s very difficult to get under control. There’s a lot of folks in America and across the world, quite frankly, suffering with it right now. The other reason it’s tough is there’s not a lot of doctors willing to treat it. There’s this whole stigma about it. What makes it particularly difficult is there’s this question on if it actually exists in some doctor’s head. It’s like the weirdest thing in the world. We know there’s this infectious agent, we know it infects humans, and yet when a human comes to the doctor and says, I’ve been infected by it, they’re like, are you sure? And so you kind of get, I think the term I hear often is medical gas lit. And on top of that, doctors, for legal reasons, often don’t want to touch it. So my doctor didn’t want to touch it. And he was like, look, you have to go to a Lyme specialist three hours away. I recommend him as best I can. And it was a long waiting list to get into this doctor’s office. And while I was waiting, just… I was relentless, you I just couldn’t sit here and let myself deal with all this. It was a three month wait. And so I just started reading voraciously on Lyme disease to your point. was reading all sorts of research. I was reading books on it, a lot of books on the, like the science and what was happening to your body mechanically. And it was actually pretty eye opening because when I started to read all these symptoms, I was like, I started to piece together all these pieces, the puzzle that happened to me in my childhood, ⁓ things that happened Cheryl McColgan (10:12)Mm. Brad Pitzele (10:13)more recently, things that the rheumatologist couldn’t explain, but now we’re clear as day what was going on. And so the jigsaw puzzle started to fall into place for me. So it was kind of an epiphany from that perspective, yeah. Cheryl McColgan (10:29)Yeah, that’s got to be the waiting had to be one of the hardest things, I’m sure. then once you finally got to him, did he because he was specialized in Lyme specifically, did he have any solutions for you? Or then was it somewhere that you still had to go to go down the road? Brad Pitzele (10:42)No. You know, the disappointing thing is, I ended up, the whole family was diagnosed with Lyme disease, not just me, my children and so forth. So we all carted in the car down three hours from, I live in Dallas area down in Austin. He had a lot of things to say to us. It was kind of stuff I’d already read. Most of it I’d already tried. know, supplements I’d already run through myself and like it became cost prohibited both the time and the visitation and we just didn’t get anywhere. So we probably visited him. five or six times and then I was like, okay, well this is not, know, and was, each time it was kind of clear, like his tools were somewhat limited. And so then it was time to kind of, while I was doing his stuff, I was also just actively experimenting. was, you know, was a, you know, a test dummy every set, every second of it, because again, you know, you just can’t wait, you know, come back in two months. You’re like, if this thing doesn’t work in a few weeks, I got to, I’ll keep doing it, but I’ll add other things. See where I go. Cheryl McColgan (11:46)Right, well, I’m sure once you knew that your whole family had this issue that probably made you want to solve it even more, not that it wasn’t enough for you to solve it for yourself, but now you’ve got other people in your family that you want to feel well, you know? Brad Pitzele (11:53)Yes. Absolutely, absolutely. was definitely set heavy on my mind. Just I didn’t want the kids to have to go down this path. Cheryl McColgan (12:06)So this kind of leads us into this whole backstory into the sign that’s behind your head right now, 1000 roads, because you kind of did that many roads to get here, right? And so what did you come across? I thought that was like one of the best business names I’ve ever seen, the way, knowing the backstory. But anyway, what was it that you found in the research or what led you to kind of, there’s a couple of things that did end up helping you, which is awesome, because I think now we’re going to share this with people because Brad Pitzele (12:16)Yeah, that’s right. you Thank you. Cheryl McColgan (12:35)Like you said, there’s plenty of people out there with Lyme disease. There’s plenty of people out there with unexplained illnesses or things that are affecting them. And, you know, there are some interesting tools that do work, worked in your case. So how did you end up finding what actually ended up working for you? Brad Pitzele (12:50)Well, I eventually started doing a lot of research on all sorts of things. And one thing that stuck with me was mitochondrial health. I hear more and more folks talking about it in recent years, which is great, but this is probably about a little 10, 12 years ago. It really wasn’t a well-spoken about area. the more I researched about mitochondrial health, the more I realized this is at the root of everything. So for your listeners, the mitochondria are this little organelle, this little subset inside all of your cells that produce the energy. And they’re extremely fragile. And when they get damaged or they’re not working efficiently, nothing works efficiently because everything takes energy, right? Us talking takes energy, thinking takes energy, moving our muscles, our organs working take energy, repair our immune system, all of it. And so often when you’re dealing with chronic health conditions, particularly when you’re dealing with an infectious agent or even cancers, they go after our mitochondria. because they kind of take the power down in the system and that gives them a leg up on our immune system and our defenses and it allows them to kind of I would call it just burrow deeper into our biology and you know shift the biology to be more favorable towards whatever that is. So for me it that was kind of an epiphany and I delved into a couple tools and the first one was something called exercise with oxygen therapy. also known as EWOT, E-W-O-T. No one was really talking about it. It was kind of the small little thing, not a lot of information out there. And then there was a second one, more folks have heard of today, which is red light therapy, and really red and near infrared light therapy. And they both work through mechanisms that help the mitochondria restore itself. Cheryl McColgan (14:45)Yeah, the exercise, I was looking at the photo on the website of the EWOT contraption and I’m kind of having a hard time conceptualizing. think what, and actually before we go into that, let’s address this other question that came up in my mind when I was looking at the contraption, because I’m like, okay, the thing that most people are probably somewhat familiar with nowadays is a hyperbaric oxygen chamber. And that is used in cancer treatment. think it was, Dr. Seyfried has this thing, and you might be familiar with him just like. through your mitochondrial research, but it’s called like a press pulse thing that they use with cancer patients. And it has to do with ketogenic diet, because you’re starving the cancer of sugar. And then also this hyperbaric oxygen therapy. That’s, that’s all just kind of a weird aside for people that are hearing this, it really has nothing to do with this conversation. But it’s interesting to look up. But for your thing, the hyperbaric works in one way. And I think people like you can visualize it, because you go in and you kind of just lay down. And that’s what it is. But this And when people go to the website, they’ll see it. It’s kind of, looks like a big balloon or a box. So guess I’m having trouble kind of conceptualizing how do you even use that or, how do you exercise with that? That’s a very long winded question, but hopefully we’ll get there. Brad Pitzele (15:47)Yeah. Sure. Well. Yeah, that’s great. So I think it’s two questions. What is it? How does it work sort of thing? Exercise with oxygen therapy at its principles really simple. It simply involves doing any sort of exercise, preferably something that gets your heart rate up, generally cardiovascular exercise, while wearing a mask and breathing near pure oxygen, so about 93 % oxygen. So to your point about how does the contraption or the EWATS system work, it works as, it’s like this, there’s actually a device called an oxygen concentrator that can produce an endless supply of oxygen. You plug it into the wall and you flip the switch and it takes the oxygen in your room, which is probably at like let’s say 21 % at sea level, and it purifies it to 93 % oxygen by separating out the other gases, the nitrogen and the argon. which is great, but these machines that you can plug into your wall, your home outlet, they produce only five or 10 liters of oxygen in a minute. And when you exercise, you can easily use 50 or 60 liters in a minute. So to get a 15 minute session in, you can easily use 900 plus liters of oxygen. And that machine’s only putting out at the best 10 liters of it. And so every minute. And so what we do is we take that machine and we fill a large reservoir to a thousand liters. So think of it as about six feet, five and a half, six feet squared. It looks like a big pillow. And we fill that thing with oxygen. Now to like dimensionalize this for folks, a thousand liters of oxygen is similar to the amount of oxygen you’ll breathe in an entire day. And we’ll fill this, this, you know, bloom, what we call a reservoir with oxygen. And then we’ll attach a hose with a mask on the end of it. Put the mask on and you just breathe out of that reservoir. of water. So again, in that 15 minutes, you can take in a whole day of oxygen. It’s really a massive amount. Now, how does it compare to hyperbaric oxygen? That’s a really good question. Hyperbaric oxygen, at its core, what you do is you get inside of a chamber, they pressurize it, and that forces more oxygen through your lung membrane and into your blood. Now, Once it gets past your lung membrane and into your blood, your, what happens in hyperbaric oxygen is it goes not just into your red blood cells, because if you look at your red blood cells right now, which are the parts of your blood that are designed to carry oxygen, they’re at capacity. Like you can put a little pulse oximeter on your finger and it’ll say 99 % or 100 % or 98%. And so there’s not room for more oxygen, but what hyperbaric does, and EWAT does the same thing, is it actually forces oxygen into your blood plasma. Now blood plasma is this clearish brown liquid, it’s effectively water plus plus, that all the red and white blood cells ride on. And so it can actually turn that into an oxygen carrying vehicle inside your blood, something that normally doesn’t carry very much oxygen. And that’s through a process called Henry’s Law, which goes beyond human biology. It’s really just a chemistry law that says, you take an insoluble gas and enforce it on top of an insoluble liquid, it’ll force the gas to go into solution. In this case, the gas is oxygen and the liquid is blood plasma. Now, in hyperbaric oxygen, the body tries to get back into balance. It notices there’s a surplus of oxygen in the blood. And so your body tries to regulate, go back to homeostasis by using something called vasoconstriction, which means your blood vessels constrict. They get smaller to allow less of that oxygen through. So your body is naturally fighting against delivering that oxygen. In spite of that, you deliver a large dose of oxygen to the tissues. In IWA, what we do is we come to the opposite. Instead of using pressure to force more oxygen into and through your lungs, we use exercise to pull it through. So when you start exercising, your body immediately recognizes that it needs more energy. And the gating factor in producing more energy is oxygen. We all in this Western world generally get enough food. It’s just we’re… When you’re exercising, there’s not enough oxygen. So when it notices this, you have all these physiological changes, right? You start breathing faster and deeper. Your lung membrane actually thins out to allow more oxygen to pass through. Your heart starts beating faster. Every beat is deeper. Your blood vessels actually dilate. They actually open up to allow larger blood flow through them. And then when you exercise, naturally, actually, your blood pressure goes up. And most of us think, no, high blood pressure is bad, but in exercise it’s actually really good because the more pressure inside your blood, that differential between the pressure in your circulatory system and the tissues is like a driving force that drives the oxygen out of the blood and into the tissues. we do EWAT, we’re taking advantage of all those physiological changes to allow us to take in oxygen very quickly and deliver it deeply into the tissues. in a 15 minute EWAT session, you could take in as much oxygen as you would in a hyperbaric session in 90 or more minutes. It’s really quite a large dose. Cheryl McColgan (21:09)Wow. then what about, so how does that affect the mitochondria? Does it just give them more energy and kind of helps them repair quicker? Or what’s the connection between mitochondrial health and the EY? Brad Pitzele (21:16)Thank This is actually the really fascinating part. And this is the thing that really got me more interested in it. EWAT was founded actually in the 1960s and 70s. There was this prolific inventor named Manfred von Arden. He was a German physicist and inventor. He invented the scanning electron microscope. He helped commercialize television technology in the 1930s. And he got interested in oxygen in 1960s and 70s because there was a gentleman named Warburg in the 1920s who had proven that he could take any cancerous cell, any regular cell and turn it into a cancerous cell simply by depriving it of oxygen. And the reverse was true. So Von Arden got interested in that, wanted to start experiment with oxygen, simply trying to reverse cancer. And along the way, what he discovered is something really powerful about our circulatory system, which is as we age, this thing we now refer to as inflammation happens inside our bodies, this slow, gradual increase in inflammation and that affects every part of our body including our circulatory system. But our circulatory system is actually kind of a weak link. At the very end of your circulatory system is your capillaries and they’re incredibly thin and they’re actually the component where the oxygen and the nutrients gets transferred from the circulatory system to the tissues. So you’ve got these really thin capillaries, thinner than a human hair, actually smaller than a red blood cell. In order for a red blood cell to get in a healthy capillary, it has to fold over like a taco to get in because it can’t fit in normal if it’s fully expanded. So there’s not a lot of room for error. And when you start having this inflammation, it causes blockages in the capillaries. So when that happens, you lose circulation downstream. You have what I call a brownout. All the cells on the other side of that inflammation are no longer getting red blood cells, they’re no longer getting oxygen. Luckily, our body does have a backup generator and that’s called anaerobic respiration. Anaerobic respiration is when they create energy without oxygen. But the problem with it is multi-fold. Number one, it only can produce about 5 % of the energy, it can produce what has oxygen. So immediately the cells are like powering down, they’re not able to do all of their essential functions. problem is it produces a massive amount of metabolic waste and free radicals and those things damage our mitochondria because our mitochondria are incredibly fragile as we spoke about earlier and they’re right at the heart of it wherever you’re producing energy you have some free radicals but now when you shift over to anaerobic all of a sudden you’re just spitting out all sorts of damaging chemicals if you will and it has no energy so it has no way to actually clear it and so it becomes I kind of call it’s like a doom loop, which is it starts with dysfunction the dysfunction causes more free radicals which causes more damage and dysfunction and Soon enough, you know, you’ve got these kind of almost zombie cells. They’re just having a hard time Doing anything and then when you do IWA what’s amazing is the oxygen because it’s Inside the plasma it can get through those blockages. So it immediately starts to feed those downstream cells the oxygen they’ve been starving but more importantly than that immediate fix if you will is they cause an anti-inflammatory effect and this was another like big aha in my healing journeys when I realized There’s plenty of research on this. Anywhere in your body you have inflammation, you have the hypoxia, which is the fancy medical term for oxygen starvation. So inflammation means local oxygen starvation. And anywhere you have oxygen starvation, you have inflammation. They go hand in hand. You can’t have one without the other. And so when we restore oxygen, even in the circulatory system, we can turn off that inflammation that’s happening in our capillaries, reestablish normal blood flow. So you get done doing your EWOT sessions. And Von Arden discovered this. had elderly people, he looked at their capillaries and their throughput, and he had them do just a couple sessions of EWOT, and they came back weeks later, and their microcirculation was still reestablished to more youthful levels. So he was able to open them back up where red blood cells were able to deliver oxygen. really at the root of it all is, you know, every chronic illness you can think of, it has inflammation. Right? mean, there’s not one Alzheimer’s, cancer, autoimmunity, the list goes on and on, name one and it has chronic inflammation. And there’s actually, there’s a gentleman, Arthur Guyton, he wrote the textbook, Medical Physiology, and every doctor any of us has ever gone to had to use that medical physiology book. when they went to medical school, it’s been the standard across the world for over 50 years. And he has this great quote where he says all disease at its root is lack of oxygen. And it’s really true because once the mitochondria break down and we start having inflammation, all the negative effects come from downstream from that. And so that was kind of my. Aha. Light bulb moment, which is if I can turn my mitochondria on it, and I can turn down the inflammation and eventually turn off the inflammation. then like my body will have energy to get ahead. can start to repair itself. It can start to detoxify the immune system. Then we’ll have energy to do everything it needs to do and help, you know, kind of kick on and start to fight a good battle, so to speak. Cheryl McColgan (26:58)Yeah, I mean, I want to go back to how this actually helped you and how you actually found one and all that stuff. But my brain is just going, the one thing that I keep coming to hearing your explanation, and that was an amazing explanation, by the way, for lay people, I can tell you’re an engineer or so. The system where you’re talking about going all the way to the capillaries, I heart disease is the number one killer, right? And we have, I think a lot of it is the chronic inflammation that you’re talking about, but. Obviously once that process is already done, you’re describing how the capillaries can’t get any red blood cells. So to me, it would make perfect sense that this might be not only did it help you in your disease process with Lyme disease and the arthritis and everything, but it seems like it would be pretty amazing for cardiovascular patients or people that don’t have good blood flow, like that on top of the mitochondrial benefit. Brad Pitzele (27:41)Hmm It’s actually, we are helping folks with everything from autoimmunity, cancer, Lyme, long COVID, chronic fatigue, Parkinson’s, heart disease, so many things, because if you can turn off the inflammation and you can give the body energy to heal, it will do just amazing things. That was kind of like the shocking thing to me when I first got into it. was like, wait a second. Like every time I was treating myself as a pin cushion and trying something new, I always had to the question like, what if this doesn’t work? and like what damage could I be doing? know, because there were things that were a little bit risky to be quite honest, where I found out risks, you know, a little bit too late for my liking. But this was one where was like, it’s oxygen. And like, so it was kind of shocking when I started looking at the benefits and I was like, this is kind of crazy that we’re talking about something as simple as oxygen with all these health benefits. But yeah, we’ve had folks with all sorts of different chronic cardiovascular conditions Cheryl McColgan (28:31)Right. Brad Pitzele (28:48)Now, there’s a lot of health benefits to it, but the other crazy thing about oxygen is there’s all these athletic performance benefits. And this is important because directly to your cardiovascular component, which is actually a lot of Olympic teams have used EWAT to improve their athletic performance. because athletic teams are very science driven, there’s some really good research on it showing it improves VO2 max, reduces recovery time. improves short-term memory, it improves power output, et cetera. And all of this is really due to being able to fuel our cells and our muscles more, and also helping clear out all that metabolic waste, because that metabolic waste primarily develops when you have a shortage of oxygen when you’re exercising. Cheryl McColgan (29:34)Amazing that something so simple could be so hugely beneficial. So once you finally saw this, you’re like, Werber knew this about cancer and this guy’s onto this exercise with oxygen thing. Like, well, how do you do it? Where do you get it? Like nobody’s ever seen this before. I think like you’re saying the athletic teams might have it and stuff, but I mean, I’ve certainly never been anywhere where I’ve seen like, hey, get EWOT therapy here. So how did you find it? Brad Pitzele (29:56)Yeah, it’s really, really kind of a rare thing. 15 years ago, it was incredibly rare. There really wasn’t anywhere to go. You could find it occasionally. You might find it in a chiropractor’s office here or there or some sort of recovery clinic. Nowadays, they’re more widespread. So there are places that do it, doctors, chiropractors. But for me, there were a couple of folks selling it, but they were… I didn’t have a whole lot of faith. There was no customer reviews. was no customers talking about it on chat. It was just them as the company and they, a lot of them spoke in superlatives and like marketing speak that it just didn’t make me feel really comfortable. And they were very expensive too. you know, they were maybe the cheapest was 5,000 and the most expensive one I saw was 25,000. and it was this kind of cross hatch of I didn’t have confidence and geez, that’s a lot of money for this next experiment when the last Cheryl McColgan (30:31)yeah. Brad Pitzele (30:49)26 behind me didn’t do anything or 57 or whatever it was. So that’s when I kind of decided, did a little bit more research and decided I was going to try to build my own. Cheryl McColgan (31:00)Yeah, was thinking that I was like, I was an engineer, the next thing would be like, can I just build this? So that’s what you did, obviously, right? Brad Pitzele (31:06)I did it out of necessity because I just didn’t have faith. I built my own. didn’t think it was, I’ll be honest, I didn’t think this was gonna be my solution. Nothing else was. And I started doing it and… You know, slowly but surely I started to walk out of that basement, that proverbial basement. I just kept taking steps up and up. At first it was subtle and then it was kind of all at once sort of thing where I was shocked. You know, was like things like, my gosh, my brain fog’s gone. I’m like focusing in a meeting or I just got down on the floor and played with the kids and I don’t need to lay in bed for two days in pain. And you know, slowly but surely I just felt better and better. And it wasn’t until I saw that same doctor again, and he was like, wow, you’re like a year later. And he was like, wow, you’re so much better. What did you do? And I told him, and he’s like, wow, would you consider selling them to my patients? And that was kind of the, you know, jumping off point where I was like, well, gosh, yeah, maybe we could help other people with this. Cheryl McColgan (32:04)Yeah, that’s awesome. I’m so glad, you know, it’s, it’s, it’s always an interesting thing on podcasts because sometimes you get, I think not on this particular podcast, but other ones, it’s like people that kind of are just selling stuff, you know, or snake oil things or whatever. But what I really love is when there are people that, you know, had their own health problem, they dive into the research, they try it all there, use themselves as an experiment as a pin cushion, as you said, and then they find something that actually works. And then they they make it so that they can share it with everybody else. don’t just keep it to yourself, because I’m sure it kind of felt like a miracle at the time if something finally worked for you. Brad Pitzele (32:41)You know, it really was. I was, because the hardest part is also when you’re in these groups and you’re talking to all these other folks and they’re like, oh, try this, nothing worked and then this worked. And you try that thing and it didn’t work. You you try 57 other different things, as I was saying, and you kind of just start losing any hope. You’re like, I don’t think, I think I’m just that case that there’s nothing that’s going to work. But yeah, when you do find it, it’s, yeah, it’s obviously life changing, even having hope and like, I always tell folks like when you’re really sick, it’s not about, you wanna get to 100%, like 100 % is amazing, it’s the dream we all have when we’re sick, but. more important than 100 % is like feeling better this week than last week or this month than last month because at some point when you’re in it, you just lose a lot of hope and it becomes kind of this like the spiral downward that you just don’t believe in anything and it just lowers you spiritually I just say. And having something to know like, hey, Yeah, it still kinda stinks, but like, remember a month ago it was worse, and so like, now you’re like, yeah, I can’t wait to see how I’m gonna be two months from now, you know, or where am gonna be by this summer sort of thing? Like, it was, it’s kinda the exact opposite. It’s kinda like this hope spiral, if you will. Cheryl McColgan (33:55)Yeah. Well, it’s kind of that’s something that I think it’s good to point out for people too, is that, you you mentioned there is all this research on this. There’s a lot of good science to back up mitochondrial health, that’s kind of mitochondrial health is kind of a long game. And it’s kind of something that you have to continually do not over, you know, just a few days and you’re going to feel so much better. It’s week after week, month after month, the more that you support your mitochondrial health, the more chance you have of really feeling better. So it’s not just this thing where you can try it for a week and you’re like, that doesn’t work. You have to keep up on it for a while, right? Brad Pitzele (34:24)Yeah. Yeah, you’re absolutely right in general speaking. mean, we have… people come to me and they ask like, how long am I going to have to do this for? I tell them is, I can’t say how long until you get to the top of the mountain, so to speak, but I find that most folks who get to the top of the mountain, they feel so good when they do it, they don’t ever want to stop. And some of those folks never really exercised, they hated it, but now they’re like, it’s like 15 minutes, I do it three or five times a week, and I feel amazing, so why wouldn’t I do it? And we talked about that capillary thinning, Cheryl McColgan (34:52)Mm-hmm. Brad Pitzele (34:58)That’s actually a chronic thing that happens to all of us in Western society. And so this is something that’s anti-aging at that very kind of cellular level. So I recommend it for folks, but. I guess for me when I was really sick, always say one of the hardest parts was the ceremony is this what they call them. Counting pills every night, doing this protocol, doing that protocol. You keep adding, like if there’s 10 more minutes in your day, you add 10 more minutes of some protocol that you’re hoping will make you feel better. And then you get to a point where you realize you’re spending six hours of your day, you know, just all you’re doing is these protocols and it just becomes overwhelming. like, even if I felt better, what’s the purpose of all I’m doing is going from from the sauna to the this and I’m doing this pill and I’m doing that. And that’s kind of the, what I found, one of the things I really loved about EWOD was it was something I could do consistently in my home, 15 minutes a day. And it helps with your mitochondrial health. It helps with detoxification. It helps with energy. So it’s like, multiple, it’s kind of multifaceted in the way it benefits you. relatively short period of time. Cheryl McColgan (36:07)Yeah, and you mentioned, and I want to be respectful of your time. know we’re kind of getting a little bit long here, but one of the other things when in respect to mitochondrial health is red light therapy. And there’s also a ton of great research on that. And so I kind of wasn’t surprised when I went to your website that that’s something that you also got into. I mean, I think that’s when you look at the number and the breadth of research on that, I think it’s pretty undeniable that it is good for people that serves a real purpose, that it does help the mitochondria. So at what point, Brad Pitzele (36:34)Yeah. Cheryl McColgan (36:35)after you found the EWAT, I’m assuming you kind of got on this mitochondrial health thing and then maybe stumbled into that stuff. that how it went or is there something else? Brad Pitzele (36:44)Yeah, I started looking at it early on, probably about six months after I was doing EWOT, four to six months right in there I’d say, I started doing Red Light. So you’re right, there’s like tens of thousands of peer-reviewed research studies out there and what it does. They work really interestingly together. Because we mentioned EWAT, when you do it, you increase the supply of oxygen massively, right? It’s a day of oxygen in 15 minutes. So you’re flooding your body with oxygen. And then if you do red light immediately afterwards, what it does is the way it primarily works is it increases oxygen demand in your mitochondria. So it forces the mitochondria to suck up more oxygen. And when they do that, they produce more energy. So any of the research you read on red light whether skin health collagen growth bone mental, brain health, me, athletic recovery performance, healing in general, it all comes from the same thing, is that it’s just forcing our mitochondria to suck up more oxygen and produce more energy. So if you compare those two, you compare them at the same time, you first drive a massive increase in supply of oxygen, and then you increase the mitochondrial demand for it, and so you get this kind of one-two punch. The interesting thing is why I think we need it in today’s society as well is we’re actually deficient on red and near infrared light. And the reason is, if you look at the sun, the sun is full spectrum. has everything from ultraviolet and the blues through the reds and the near infrareds. So when you go outside and it changes throughout the day, early and late in the day, you get more of those reds and near infrareds. And at high noon, you get more of the blues. unfortunately, or fortunately, however you want to look at it, over time as as ⁓ species, we’ve moved indoors and we started using indoor lighting primarily and we spend more and more time there. And then more recently, we’ve switched from incandescent to LED lighting. Now, LED lighting is very energy efficient and one of ways they make it incredibly energy efficient is they take out all the reds and the near infrareds that we experience as heat because obviously you don’t want your lighting to heat your room. You don’t want it to, everyone sees that as energy. waste and to that extent you’re trying to use it for lighting it can be. However, that puts us in a place where we spend a lot of time bathed in blue lights and not really getting enough of the reds and the other parts of the spectrum. Cheryl McColgan (39:27)Yeah, that’s another interesting rabbit hole for people to go down if they haven’t already is just the, you know, changing out some of the lighting in your home or using specific lighting for certain scenarios, like in your bedroom and towards night as you’re getting ready to go to sleep. But anyway, I just want to clarify one quick point there, because I’m envisioning, that was actually what I was envisioning when you started talking about the synergy between red light and the EWAT. So do you like do your EWAT with the red light panel like in front of you or do you just do it right after? Brad Pitzele (39:53)Yeah. I prefer to do it right after. The challenge with doing it right on you is to get the best benefit from red light. Red light works on something called a biphasic dose response, fancy science term, which just means the benefits over time look like a bell curve. So too little, you won’t get any benefit. There’s kind of like a just right where you get peak benefit. And then if you do more, it starts diminishing in benefit. It doesn’t harm. It’s just a waste of time, right? So you spent five more minutes to get less sort of thing. Cheryl McColgan (40:21)Mm-hmm. Brad Pitzele (40:22)with exercising in red light is one, I like to get as much skin exposure as possible so you’re hitting as many mitochondria as possible. And two is you’re moving. So sometimes you’re close to the light, sometimes you’re further away. And so you’re not really able to kind of measure that dose effectively to get inside that biphasic kind of peak zone. Cheryl McColgan (40:43)Okay, no, that makes a ton of sense. Although I still am going to put this out to you that, maybe you put at least on, you know, the little face mask while you’re exercising. I feel like you can attach it to the oxygen part, you know, and just put a red light around it. Maybe that’s a little too, maybe that’s a little too much. But anyway, well, Brad, this has been so wonderful. And I just appreciate you so much sharing your whole journey and then how you came to find this. Brad Pitzele (40:51)There you go. It makes yours waterproof. That’d be fun. Cheryl McColgan (41:09)If people want to connect with you online or learn more about EWOT and learn more about Red Light, where’s the best place that they can find you and connect with you? Brad Pitzele (41:17)Yeah, go to 1000roads.com slash Cheryl and we have a great offer for your listeners. They can check out. You can also ⁓ go to our YouTube channel. put out weekly videos. 1000roads, HQ is our channel. It’s all spelled out, O-N-E-T-H-O-U-S-A-N-D-R-O-A-D-S.com. Cheryl McColgan (41:25)Awesome. Okay, awesome, and all that will be in the show notes for everyone, so don’t feel like you have to write it down. But Brad, again, thank you so much for coming and sharing your knowledge today, and I really appreciate it. Brad Pitzele (41:46)Thank you so much, Cheryl.

This special Tick Boot Camp Podcast crossover features the full International Lyme and Associated Diseases Society (ILADS) webinar recording, “At the Frontlines of Chronic Illness: Conversations with ILADS Experts.” In this dynamic panel discussion, leading clinicians and specialists unpack why Lyme disease and other infection-associated chronic illnesses are so misunderstood, why testing fails so many patients, and what it really takes to heal—brain, immune system, mitochondria, and terrain included. Moderated by Rich Johannesen (Tick Boot Camp), the panel delivers practical insights and hopeful, patient-centered guidance for anyone navigating complex chronic illness—whether you're a patient, caregiver, clinician, or advocate. Featured Panelists Chris Winfrey, MD — Psychiatrist; Medical Director, New Image Wellness Nicole Bell — “The Lyme Disease Engineer”; CEO, Galaxy Diagnostics Tania Dempsey, MD — Medical Director, AIM Center for Personalized Medicine Melanie Stein, ND — Naturopathic Doctor; Author focused on cellular wellness and healing terrain Host/Moderator: Rich Johannesen (Tick Boot Camp) ILADS Intro: Ali Moresco (ILADS) Episode Highlights ILADS Mission and Why This Webinar Matters The webinar opens with ILADS' mission: improving diagnosis and treatment of Lyme disease and associated illnesses through research, education, and policy. ILADS emphasizes physician training and patient-centered care, while also supporting the educational mission of ILADEF. Rich frames the night as a rare opportunity to hear from experts working at the front lines of complex chronic illness—especially for patients who've been dismissed, misdiagnosed, or told their symptoms “don't make sense.” Segment 1: Brain Health, Neuroimmune Illness, and Why Lyme “Feels Like Dementia” Chris Winfrey, MD Dr. Winfrey introduces a core theme: Lyme is not only an infection—it often behaves like a neuroimmune illness. Key takeaways: The brain is a high-energy, high-immune-demand organ, uniquely vulnerable to infection-driven inflammation and toxicity. Lyme can disrupt brain function through: Blood flow issues Synaptic dysfunction Myelin damage Network-level disruption, not just “neurotransmitters” He describes brain function through networks that Lyme can destabilize: Default Mode Network (internal reflection) Salience Network (switching between networks) Central Executive Network (planning/organization) Action Network (execution) Autonomic Network (regulation) Limbic Network (threat/fear response) The result: patients often describe “brain shutdown,” confusion, cognitive impairment, and even dementia-like symptoms. A major reframing: Emotions are not “non-physical.” They are measurable physiological states. Lyme-driven nervous system injury can create emotional disturbance because the biology is disturbed. Segment 2: Poly-microbial Infection, Fight-or-Flight, and the Belief-Healing Loop Winfrey + Rich Discussion Rich frames humans as spiritual, emotional, and physical beings, and asks how chronic infection impacts both body and emotional resilience. Key points: Lyme can cross the blood-brain barrier and affect virtually any organ system. The nervous system becomes a “central battleground,” and measurement is hard because nervous system dysfunction isn't captured well by simple bloodwork. Rich and Dr. Winfrey explore how illness disrupts perception, decision-making, and our ability to interpret the world—especially when gut function and intuition feel “offline.” The healing paradox: Chronic stress and “fighting your way to healing” can backfire. Dr. Winfrey emphasizes that healing requires a parasympathetic state—rest, digest, repair—and that this often involves acceptance, surrender, trust, and safety. Segment 3: The State of Testing—Why So Many Patients Test Negative Nicole Bell (Galaxy Diagnostics) Nicole shares her personal motivation and professional mission: testing determines treatment, reimbursement, and belief—and too many patients are failed by existing tools. Indirect testing (antibody testing): The standard approach relies on antibodies—meaning it depends on the immune system behaving predictably. But Lyme and other stealth pathogens evade and suppress immune responses. Even in controlled research models, two infected subjects can show completely different antibody patterns. Immunosuppression (illness severity, medications like steroids, immune dysregulation) can reduce antibody reliability. Direct testing (pathogen detection):Nicole contrasts Lyme testing with illnesses like COVID—where you use tests that look for the pathogen itself (PCR/antigen), not just antibodies. Why direct detection is hard in Lyme: Pathogens can be low abundance They can be tissue-sequestered Sampling matters Why urine can matter for Lyme: Lyme may not stay in blood, but it can shed proteins/antigens that filter into urine. Galaxy's approach includes methods to capture, concentrate, and detect those markers. New diagnostics focus: Genus-level screening for the “3Bs” (Borrelia, Bartonella, Babesia) Reducing guessing when symptoms overlap and co-infections “masquerade” as each other Segment 4: Immune Dysfunction, Mast Cells, and Why Antibody Testing Can Go Haywire Tania Dempsey, MD (AIM Center for Personalized Medicine) Dr. Dempsey explains the immune system through two major branches: Innate immune system (fast, primitive defense) Adaptive immune system (antibodies, longer-term response) Mast cells as first responders: Mast cells detect “danger” and release inflammatory mediators (histamine and many others). In chronic infection, mast cells can remain persistently activated, releasing hundreds of inflammatory compounds. Why antibody tests fail (two patterns): Immune suppression → insufficient antibody production → false negatives Immune chaos → excessive, inappropriate antibody production → confusing positives - Positive Lyme bands “everywhere” - Positive autoantibodies without classic autoimmune disease patterns - “Everything looks positive” because signaling is dysfunctional Her central philosophy:It's not only about killing the bug. It's about fixing immune regulation so the body can actually clear or control infection. She also names the broader context: modern toxic load (mold, plastics, pesticides, “forever chemicals”) primes the immune system into dysregulation before infections even arrive. Segment 5: Advanced Immune-Modulating Tools Therapeutic Plasma Exchange + SOT Dr. Dempsey discusses therapies she's excited about, especially for complex, stuck cases: Therapeutic Plasma Exchange (TPE / plasmapheresis): Removes plasma (where antibodies, inflammatory mediators, and “garbage” accumulate) Replaces with albumin (and sometimes IVIG) Concept: reduce inflammatory burden + toxic load to reset the terrain SOT (Supportive Oligonucleotide Technique): Molecular targeted approach designed to reduce replication of specific pathogens More targeted than “wide-net” antimicrobial approaches Used strategically after lowering inflammatory/toxic burden She emphasizes: not for everyone, not a universal cure—but promising enough to merit formal publication. Segment 6: GLP-1 Agonists and Mast Cell Stabilization “Brain-melt” moment, revisited Dr. Dempsey explains why drugs commonly known for diabetes/weight loss may have immune benefits: Mast cells have receptors for GLP and GIP hormones Patients showed improvements beyond weight: cognitive function, inflammation, immune stability She describes: Semaglutide (Ozempic/Wegovy) Tirzepatide (Mounjaro/Zepbound) Emerging triple agonists (GLP-1/GIP/glucagon pathways) Her clinical approach has moved these agents earlier in care plans for immune stabilization in select cases. Segment 7: Cellular Healing, Mitochondria, and the Terrain Melanie Stein, ND Dr. Stein brings it home: healing often stalls when we focus only on killing pathogens, but don't repair the cellular damage. Core concepts: Lyme damages cell membranes, disrupting what goes in/out and how cells communicate. It contributes to mitochondrial dysfunction, reducing ATP (energy currency). If cells stay in “alarm mode,” healing remains blocked. Cell membrane therapy and terrain support: IV and oral lipid support (phospholipids, phosphatidylcholine, omega fatty acids) Personalized support based on lipidomic patterns Supportive therapies to reduce oxidative stress and “toxic fats” Focus on signaling safety to the body—so repair can resume Cell Danger Response:A key theme: even after infections reduce, the body may remain stuck in a persistent defense state, requiring cellular and nervous system support to exit “danger mode.” Regulation Before Eradication Panel Reflection Round As the panel closes, several themes converge: Limbic system + autonomic nervous system regulation is foundational “Regulation becomes before eradication” Healing requires safety, predictability, and nervous system calm Chronic illness can block our ability to connect—especially in relationships—because survival physiology dominates Dr. Dempsey adds that limbic retraining / nervous system reset is often the first step she starts with in her practice. Question and Answer Highlights Lyme and Cancer? The panel notes emerging signals connecting tick-borne illness and certain cancers, but emphasizes that more research is needed to determine causality. Herniated discs, connective tissue, and chronic infection The discussion highlights potential links through: connective tissue disruption collagen damage mast cell mediators (enzymes that affect tissue integrity) infection-driven inflammation Cross-reactive antibody results (example: Brucella) The group explains how antibody testing can produce confusing results due to immune dysregulation and cross-reactivity—another reason why interpretation and test methodology matter. Nasal testing / sinus terrain While not a mainstream Lyme diagnostic route, the panel references nasal/sinus colonization (especially with mold-related or chronic inflammatory patterns) as a terrain factor that can influence recovery. Resources Mentioned Center for Lyme Action – State of Lyme Disease Research paper (Nicole Bell collaboration) ILADS Provider Search International Lyme and Associated Diseases Educational Foundation (ILADEF) Donations (supports education and clinician training) Final Message to Listeners This episode is a reminder that Lyme disease and infection-associated chronic illness are not one-dimensional problems. The path forward often requires: better diagnostics immune regulation nervous system support cellular repair personalized care and hope that the body can recover when the right puzzle pieces come together

In this powerful in-person interview at the Tick Boot Camp studio, Matt Sabatello sits down with Dr. Somer DelSignore, DNP, a board-certified pediatric practitioner specializing in Lyme disease, tick-borne co-infections, PANS/PANDAS, autoimmune and neuroimmune disorders, autism-like regression, and congenital tick-borne illness. This episode is essential listening for parents who have been told to “wait and see,” families who have seen multiple specialists without answers, and anyone trying to understand how infection, inflammation, immune dysfunction, and nervous system imbalance can impact a child's brain and development.

This week's stories: *Bartonella Hides in Cat Scratches — and It Might Be Why You Feel Like Garbage A stealth bacterial infection transmitted by everyday cat scratches and flea dirt has been quietly linked to chronic fatigue, brain fog, and neurological symptoms for decades. Dave breaks down how Bartonella slips past standard testing, why it's almost never on a conventional doctor's radar, and the specific PCR protocol you need to actually find it. Sources: https://pubmed.ncbi.nlm.nih.gov/ *High Tyrosine Levels May Be Cutting Years Off Men's Lives A Mendelian randomization study of 270,000 UK Biobank participants found that elevated tyrosine is causally linked to nearly a full year of lost lifespan in men — with zero effect in women. The culprit appears to be an inflammatory oxidation pathway that men metabolize very differently. Dave examines what this means for every guy stacking L-tyrosine nootropics or eating high-protein keto. Sources: https://pubmed.ncbi.nlm.nih.gov/41045493/ https://www.aging-us.com/news-room/high-tyrosine-levels-linked-to-shorter-lifespan-in-men https://www.usnews.com/news/health-news/articles/2026-02-27/study-suggests-one-common-amino-acid-may-affect-how-long-men-live *Blue Light Blocking Contact Lenses Are a Legitimate Vision Upgrade ALTIUS Vision's tinted contact lenses aren't just blue light filters — they cut chromatic aberration by 53% and improve motion tracking and contrast sensitivity in ways that software filters simply can't replicate. Dave covers the mechanism, who benefits most (screen workers, TBI recovery, gamers), and how to find a provider. Sources: https://altiusvision.com/chromatic-aberration/ https://altiusvision.com/science-of-altius/ https://www.westvalleyvision.com/-altius--performance-tinted-contact-lenses *Taurine Plus B Vitamins Actually Moves the Needle on Motivation A randomized crossover trial found that a daily stack of taurine, B6, folate, and B12 sustained effort-reward motivation and cut cognitive lapses significantly compared to placebo — and the mechanism runs through glutathione production in brain astrocytes. Dave breaks down why this combo works when either ingredient alone doesn't. Sources: https://pubmed.ncbi.nlm.nih.gov/41889717/ https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2026.1711478/full https://www.nutraingredients.com/Article/2026/03/23/taurine-and-b-vitamins-bost-motivation-and-focus/ *30 Seconds of Smelling Flowers Resets Your Nervous System Research out of the Monell Chemical Senses Center confirms what your grandmother knew: a slow, deep floral inhale measurably lowers heart rate and activates the parasympathetic nervous system — and it works because olfaction bypasses the cortex entirely and hits the limbic system directly. Dave makes the case for building a daily scent ritual. Sources: https://time.com/ https://www.southtabor.com/healthy-living-tip-stop-and-smell-the-flowers/ This episode is designed for biohackers, longevity seekers, and high-performance listeners who want mechanism-level clarity on infection-driven cognitive decline, amino acid optimization, sensory performance, and evidence-based supplementation. Host Dave Asprey connects emerging clinical research, Mendelian randomization data, and real-world protocols into actionable frameworks for extending healthspan and sharpening performance. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: Bartonella cat scratch infection, Bartonella brain fog chronic fatigue, stealth bacterial infection biohacking, tyrosine lifespan men, L-tyrosine risk men longevity, Mendelian randomization amino acid aging, blue light blocking contacts, ALTIUS vision chromatic aberration, performance contact lenses TBI, taurine B vitamins motivation RCT, taurine folate brain health, glutathione astrocytes focus, smelling flowers heart rate stress, olfaction parasympathetic nervous system, floral scent limbic system, biohacking news, longevity research 2026 Thank you to our sponsors! - GOT MOLD? | Go to http://gotmold.com/shop and use DAVE10 to save 10% and see what's in your air. - MASA Chips | Go to https://www.masachips.com/DAVEASPREY and use code DAVEASPREY for 25% off your first order. - iRestore | Grow thicker, healthier hair back naturally. Use code DAVE at irestore.com. Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro 00:37 – Bartonella & Cat Scratch Disease 02:06 – Tyrosine & Lifespan in Men 03:37 – Tinted Contacts & Visual Processing 05:56 – Taurine & Motivation 07:25 – Floral Scent & Nervous System Reset See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Frédéric Roscop, French-born osteopath and founder of AEQUIL, joins the Tick Boot Camp Podcast as our first-ever in-studio international guest, flying in from London to Long Island to share his personal battle with chronic Lyme disease—and the breakthrough that reshaped his life and career. After decades of unexplained symptoms, misdiagnoses, heart inflammation, neurological dysfunction, and failed treatment attempts across multiple countries, Frédéric discovered that killing microbes alone wasn't enough. His recovery began when he shifted focus from chasing pathogens to restoring the body's foundational terrain—supporting immune regulation, detoxification, cellular function, stress physiology, and energetic balance. In this deeply reflective and technical conversation, Frédéric shares how childhood tick exposure in rural France, years of undiagnosed Borrelia and Bartonella infection, and repeated medical dead-ends ultimately led him to develop a patented biotech system designed to help others reset their foundational wellbeing. What You'll Learn in This Episode Growing Up in Tick Territory Frédéric describes growing up in rural France, frequently covered in ticks as a child—long before Lyme disease was widely recognized in Europe. Early symptoms included: Chronic insomnia and hyperactivity Digestive dysfunction and blood sugar instability Visual disturbances and light sensitivity Emotional instability and neurological symptoms Recurrent inflammation At 16, following general anesthesia for a broken nose, he experienced what he now recognizes as a major Lyme “crash,” leading to cognitive decline, emotional dysregulation, and worsening physical inflammation. Heart Inflammation & Athletic Collapse By age 17–18, Frédéric's promising volleyball career ended due to inflammatory joint disease and recurring pericarditis (heart inflammation)—which would return six times over the next 15 years. Antibiotics temporarily improved symptoms, but the root cause remained unidentified. “I Didn't Even Know What Lyme Disease Was” As a young osteopath in practice, Frédéric recalls a patient asking whether her symptoms could be Lyme disease. At the time, he had never been trained on it. Years later, another patient was hospitalized with Lyme-related encephalitis—triggering Frédéric's realization that Lyme might explain both his patients' suffering and his own. This episode includes an honest discussion about: Medical training gaps Diagnostic limitations The importance of humility in healthcare Why the doctor–patient relationship must be a partnership Diagnosis: Borrelia, Bartonella & More Specialty testing eventually revealed: Borrelia Bartonella Viral findings including Epstein-Barr Virus (EBV) Heavy metal burden (notably elevated mercury) Frédéric began aggressive antibiotic and detox protocols—but experienced severe gut collapse and worsening terrain. Despite trying treatments across Europe, the U.S., China, India, and Switzerland—including antimicrobial, herbal, and integrative approaches—he improved only marginally. The Turning Point: It's Not Just the Bug — It's the Terrain Frédéric revisited the foundational debate in medicine: Louis Pasteur: It's the germ. Claude Bernard: It's the terrain. His breakthrough came when he shifted focus to rebuilding: Gut function Cellular membranes Detox pathways Nervous system regulation Emotional and energetic resilience Rather than focusing exclusively on killing microbes, he asked: Does the body have the capacity to self-regulate and self-repair? From that question, AEQUIL was born. What Is AEQUIL? AEQUIL is a biotech wellness system built around a patented technology Frédéric calls Liquid Intelligence — a formulation combining: Structured/dynamised water Botanicals Vitamins and electrolytes Biochemical and biophysical support The system supports: Brain, heart, gut, liver, and immune foundations Detoxification and lymphatic flow Stress physiology Emotional and energetic regulation The AEQUIL Deep Reset System Maintain (Foundational Support) A daily liquid formula designed to nourish the body's core systems and support cellular regulation. Suggested use: ½ teaspoon morning ½ teaspoon evening Reset (Deep Reset Protocol) A structured approach to support: Microorganisms (bacteria, viruses, fungi, parasites) Micro-toxins (detox pathways) Micro-traumas (stress and emotional stagnation) The protocol is phased to reduce Herx reactions and build resilience gradually, with many users reporting a noticeable physiological shift around weeks 8–10. Everyday Support Wearable patches and digital wellness tools (affirmations, breathwork) designed to support mood, sleep, energy, and immune balance during recovery. Core Message of This Episode Chronic Lyme recovery is rarely about one silver bullet. It requires: Restoring foundational systems Supporting detox and immune function Addressing nervous system and stress patterns Recognizing both biochemical and energetic influences Frédéric's story is one of humility, evolution, and transformation—from a practitioner unaware of Lyme disease to a global wellness innovator working to support both patients and healthcare providers.

In this episode of Resiliency Radio with Dr. Jill, Dr. Jill Carnahan explores the growing science behind brain inflammation and its connection to chronic illness with Dr. Eboni Cornish. Dr. Cornish, Associate Medical Director at Amen Clinics and Treasurer of the International Lyme and Associated Diseases Society, shares how underlying inflammation in the brain can drive symptoms often labeled as psychiatric, neurological, or behavioral conditions. Together, they discuss how mold toxicity, chronic infections, gut dysfunction, hormone imbalances, and environmental toxins can disrupt brain health and lead to symptoms such as brain fog, anxiety, depression, personality changes, and fatigue. This powerful conversation highlights the importance of identifying root causes of neuroinflammation and offers hope for individuals struggling with complex chronic conditions through advanced diagnostics, functional medicine strategies, and personalized care.

In this episode of the Innovations and Clinical Implementation podcast, hosts Jessica Carter and Dr. Chris D'Adamo interview Dr. Jill Carnahan, a functional medicine physician internationally recognized for treating complex chronic illnesses, about the critical role of beta glucans in immune resilience – which she champions as the foundation of longevity. Dr. Carnahan, discusses the importance of using high-purity beta glucans, profiling BWH Labs' flagship product, and details their use in treating complex conditions like Lyme disease, Bartonella, and cancer where the immune system is often suppressed. The conversation also covers emerging research linking beta-glucan supplementation to improved mental health scores (anxiety and depression) and its mechanism as a binder in detoxification pathways for removing environmental toxins. Finally, Dr. Carnahan underscores that while lifestyle factors like sleep and movement are foundational, beta-glucans serve as a crucial tool for "waking up" sluggish T-cells and Natural Killer cells to fight aging and chronic illness. For access to episode resources, click HERE.

Ever feel exhausted no matter what you try, or notice new symptoms you can't explain since 2020? Dr. Evan Hirsch reveals the Toxic Five framework, the hidden combination of heavy metals, chemicals, molds, infections, & nervous system dysfunction that are the real root causes of chronic fatigue, long COVID, & autoimmunity. Meet our guest  Dr. Evan Hirsch is a board-certified MD and the founder of EnergyMD, where he specializes in treating chronic fatigue syndrome and long COVID. He has spent over a decade helping thousands of patients identify and address the root causes of their low energy. Dr. Hirsch resolved his own chronic fatigue syndrome using the same Toxic Five framework he now teaches. His 4-step process uses 100% natural tinctures and supplements, increased one drop at a time, to systematically detoxify at a rate each individual can tolerate. He operates online as a health coach and hosts the EnergyMD Podcast. Thank you to our partners Outliyr Biohacker's Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways About 36% of everyone who has had COVID develops persistent symptoms, making it a trillion-dollar annual problem most people don't even realize they have The Toxic Five (heavy metals, chemicals, molds, infections, nervous system dysfunction) cause 80% of the deficiencies that functional medicine typically treats as primary problem Over 90% of chronic fatigue cases can be identified through patient history & symptoms alone, saving thousands in unnecessary lab work Illness operates on 3 levels: lifestyle fixes, replacing deficiencies (adrenals, mitochondria, thyroid), & full Toxic Five removal for stubborn cases Biofilms shelter infections & toxins in a toxic matrix. COVID disrupts these biofilms, releasing dormant infections like Bartonella & Babesia A free 4-step mindset practice (gratitude, vision, belief flipping, empowering questions) combined with vagal toning rewires the nervous system Peptides, stem cells, ozone, & other advanced biohacks work best after 6-12 months of Toxic Five treatment, not before Episode highlights 00:55 Why most people have long COVID and don't even know it 03:10 The Toxic Five that are secretly draining your energy 04:19 How your pet could be making you sick & the symptoms to watch for 07:47 The 3 levels of illness and what to do at each one 13:59 The one-drop method that prevents detox disasters 30:01 A free daily practice that rewires your nervous system 34:06 Why peptides, stem cells, and biohacks keep failing you Links Watch it on YouTube: https://youtu.be/Jmmu-U4wmyg  Full episode show notes: http://outliyr.com/253  Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

This is episode 078 of the Love, Hope, Lyme podcast. This podcast does not replace medical treatment. If you are suffering from Lyme and other tick-borne disease, please seek proper medical treatment. Pennsylvania has been called a ground zero of the Lyme disease epidemic in the United States. On this episode of the Love, Hope, Lyme Podcast, Fred Diamond speaks with two powerful advocates who are working to change that reality. Eric Huck and Amy Tiehel from the Pennsylvania Lyme Resource Network share their deeply personal Lyme journeys and explain why advocacy, education, and community support are critical for Lyme survivors and their families. Eric's story began in 2009 after a tick bite while hiking the Appalachian Trail. Despite early treatment, his health rapidly deteriorated and he was eventually diagnosed with Lyme disease along with multiple co-infections including Babesia, Bartonella, Ehrlichiosis, and Anaplasmosis. His experience navigating the healthcare system ultimately led him to help build one of the largest Lyme advocacy organizations in the state. Amy's journey began while she was living in Los Angeles. After years of debilitating symptoms, Bell's palsy, and visits to more than 25 doctors, she was finally diagnosed with Lyme disease and Babesia. Her experience with misdiagnosis and medical dismissal pushed her into advocacy so that other patients would not have to navigate the system alone. In this powerful conversation, we discuss: • Why Pennsylvania has become a Lyme disease hotspot • The mission of the Pennsylvania Lyme Resource Network  • The challenges patients face with diagnosis and treatment  • The mental and emotional toll Lyme takes on families • Prevention through the Dare 2B Tick Aware education program • What must change to improve care for Lyme survivors Eric and Amy also share details about the Pennsylvania Lyme Patient Conference taking place April 18 in King of Prussia, where patients, doctors, and advocates will gather to learn, connect, and support one another. Learn more about the Pennsylvania Lyme Patient Conference: https://palyme.org

In this powerful and science-forward episode of the Tick Boot Camp Podcast, host Matt Sabatello sits down with Amy Proal, PhD, a leading microbiologist whose work is reshaping how the medical community understands chronic Lyme disease, post-treatment Lyme disease (PTLD), ME/CFS, and Long COVID. Dr. Proal brings a rare combination of deep scientific expertise, lived experience with chronic illness, and real-world clinical integration, offering listeners clarity on why so many patients remain sick long after standard treatment ends — and what science is finally doing about it.

What if Alzheimer's, multiple sclerosis, chronic fatigue, and even psychiatric symptoms are not random but driven by hidden infections? In this episode of Integrative Lyme Solutions, Dr. K sits down with research scientist and Lyme survivor Nikki Schultek to explore the infection hypothesis behind chronic disease. After battling years of misdiagnosed symptoms including asthma flares, interstitial cystitis, arrhythmias, neurological decline, and suspected MS, Nikki uncovered a complex web of infections including Borrelia, Bartonella, Babesia, Chlamydia pneumoniae, Epstein-Barr virus, and more. Now founder of the Alzheimer's Pathobiome Initiative, Nikki is leading a global consortium investigating how stealth pathogens may trigger neurodegeneration, immune dysfunction, and dementia. This conversation dives into intracellular infections, the Herxheimer reaction, amyloid as an antimicrobial response, sterile brain autopsies, precision medicine, and why federal health agencies are finally acknowledging Lyme disease as a serious public health crisis. If you or someone you love is dealing with chronic Lyme, long COVID, autoimmune illness, or cognitive decline, this episode may change how you see disease. Key Takeaways: 0:00 Introduction 3:15 Asthma, air hunger, and early misdiagnoses 8:40 From interstitial cystitis to suspected multiple sclerosis 14:30 Discovering intracellular infections and Chlamydia pneumoniae 18:45 Lyme, Bartonella, Babesia and the whack-a-mole effect 24:10 The Pathobiome concept and microbial imbalance 27:30 Alzheimer's disease and the infection hypothesis 32:00 Sterile brain autopsies and spinal fluid research 35:20 Amyloid plaque as an antimicrobial defense mechanism 41:00 APOE4, genetics, and infection susceptibility 44:30 Federal recognition of Lyme disease and future funding Resources Mentioned: Alzheimer's Pathobiome Initiative - https://alzheimerspathobiome.org ILADS - https://www.ilads.org ILADS Education Foundation - https://www.iladef.org Philadelphia College of Osteopathic Medicine - https://www.pcom.edu Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions. _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email info@TheKarlfeldtCenter.comCheck out Dr. K's Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

In this groundbreaking episode of the Tick Boot Camp Podcast, we interview Dr. Jayakumar Rajadas, a Stanford Medicine researcher who has discovered multiple breakthrough therapeutic candidates for Lyme disease, Babesia, and Bartonella. His work includes the discovery of Disulfiram's effectiveness against Lyme and Babesia, Azlocillin's potent activity against Lyme and Bartonella, and advanced targeted drug-delivery systems designed to preserve the gut microbiome. Dr. Jay's research has been featured in TIME Magazine (Azlocillin) and Forbes (Disulfiram), and connects deeply with the work of leading Lyme researchers, including Dr. Monica Embers (Tulane), Dr. Kim Lewis (Northeastern), Dr. Kenneth Liegner, and Dr. Brian Fallon (Columbia University). This interview delivers hope, science, and unprecedented detail on what may become the next generation of Lyme disease treatments. Key Topics Covered 1. How the Stanford Tick Initiative Sparked a New Era of Drug Discovery In 2012, Stanford launched a major initiative in response to community demand for better Lyme treatments. Dr. Rajadas was selected to lead drug development, focusing specifically on persistent/chronic Lyme disease, where few researchers were working. 2. Understanding Borrelia: Active vs. Stationary Forms & Why Chronic Lyme Persists Dr. J explains the three key survival modes of Borrelia burgdorferi: Active Phase The bacteria are replicating and metabolically active. Easier to kill with standard antibiotics. Stationary Phase Bacteria reach population limits and slow down growth. Represents early persistence mechanisms. Persister Forms Triggered by stressors like antibiotics (e.g., doxycycline). Bacteria fold into round bodies, spiral forms, or compact “cement-like” protective balls. These forms: Shut down metabolic pathways Resist penetration Survive antibiotic exposure Why Doxycycline Can Fail Doxycycline can induce persisters, causing Borrelia to form impenetrable protective shells rather than die. This is why many patients initially feel better, then relapse. 3. Disulfiram (Antabuse): Lyme + Babesia Breakthrough Featured in Forbes One of the biggest scientific shocks of the last decade: Discovery Through Stanford's high-throughput screening of FDA-approved drugs, Disulfiram emerged as a top hit. Clears Borrelia (including persistent forms) Clears Babesia — a major advantage over standard antibiotics Does NOT harm the gut microbiome Is already FDA-approved and widely used for alcohol aversion therapy Highly potent but requires careful dosing due to side effects in inflamed patients. Why Some Patients Improve, and Others Suffer Chronic Lyme patients already have heightened inflammation. Disulfiram is a powerful molecule whose polymorphic forms behave differently in different people. His lab developed: Less toxic formulations Buccal & sublingual delivery systems Rectal delivery options These may reduce neuropsychiatric side effects reported by some patients. Clinical Connections Dr. Kenneth Liegner pioneered clinical use and published cases Dr. Brian Fallon conducted NIH-listed clinical trials. Many clinicians now use Liegner's protocols. Real-world example: Matt shares the story of Brooke Stoddard (Generation Lyme), who regained his life after Disulfiram treatment under Dr. Liegner. 4. Azlocillin: The Antibiotic That TIME Magazine Called a Gamechanger If Disulfiram is the Lyme and Babesia weapon, Azlocillin may be the frontline tool for Lyme and Bartonella. Why Azlocillin Is Revolutionary Eradicates both active and persister forms of Borrelia. Destroys doxycycline-induced “cement ball” persisters by drilling into their vulnerable cell-wall synthesis pathways. Proven effective against Bartonella when paired with azithromycin, based on research by Dr. Monica Embers (Tulane) . The Cell-Wall Vulnerability Breakthrough Persisters STILL must maintain minimal cell-wall synthesis to survive. Azlocillin exploits this tiny vulnerability: It penetrates the protective sphere Breaks the “cement wall” Forces the bacteria out of hibernation Kills them rapidly This discovery is one of the biggest scientific leaps in Lyme research in a decade. The Delivery System That Protects the Gut Microbiome Azlocillin is extremely hydrophilic, making absorption difficult.Dr. Jay fixed this by creating: A magnesium-lipid nanoparticle formulation Designed to release in the upper intestine Avoiding the colon (where most microbiome lives) This allows: High bloodstream absorption Minimal microbiome damage Oral availability of a drug previously only available via IV Why Azlocillin May Be Better Than Disulfiram Hits Borrelia + Bartonella Stronger anti-inflammatory effects No polymorphism issues Fewer side effects Potent against persisters A company is preparing to bring his oral formulation to clinical trials by next year. 5. Loratadine (Claritin): The First Clue from 2012 Before Disulfiram and Azlocillin, Dr. Jay's lab identified Loratadine (Claritin) as a manganese transporter inhibitor of Borrelia. Why it mattered: Borrelia uniquely relies on manganese, not iron. Blocking manganese uptake may weaken the bacteria. The discovery went viral, with many patients reporting improvement even at OTC doses—though the binding affinity was weak. This project introduced the concept of drug repurposing for Lyme to the scientific community. 6. Melittin (Bee Venom) — The Micro-Needle Patch Alternative Bee venom therapy is widely used in the Lyme community, but risks stings and allergic reactions. Dr. J is developing: Melittin micro-needle patches Delivering the active peptide without stinging Using dissolvable, painless needles A safe, controlled, pharmaceutical-grade delivery approach This could modernize bee venom therapy and make it more accessible. 7. Mechanism of Brain Fog & Fatigue in Lyme: A Major Breakthrough Dr. Jay's lab published a neuroscience paper demonstrating: Outer Surface Protein (Osp) Nanoparticles Borrelia sheds lipid-coated outer membrane particles. These form stable nano-vesicles that: Enter the bloodstream Cross into the brain Cause mitochondrial dysfunction Reduce ATP production Result: Brain Fog, Fatigue, Cognitive Dysfunction This explains why neurological Lyme can persist even after bacterial levels drop. This work ties strongly to ongoing research at Columbia University under Dr. Brian Fallon. 8. Collaborations With World Leaders in Lyme Research Dr. J's research intersects with: Dr. Kim Lewis (Northeastern University) Reproduced and validated Disulfiram findings publicly. Helped launch interest in persister-killing therapies. Dr. Monica Embers (Tulane University) Demonstrated Azlocillin + Azithromycin effectiveness against Bartonella. One of the world's foremost experts in persistent infection models. Dr. Kenneth Liegner Early clinical pioneer of Disulfiram therapy. Published stunning recovery cases. Dr. Brian A. Fallon (Columbia University) Leading psychiatrist specializing in post-treatment Lyme. Conducted planned Disulfiram clinical trials. These collaborations form a powerful network accelerating treatment development. 9. New Anti-Inflammatory Discoveries: Galangin & More Dr. Jay recently co-authored a 2025 paper on: Galangin (Thai ginger rhizome extract) Which may reverse cardiac inflammation and fibrosis His team is also exploring other nutraceutical molecules for chronic inflammation relief in Lyme patients. 10. Dr. Jay's Personal Story of Illness and Hope He reveals for the first time: He was diagnosed with Stage 3 Multiple Myeloma Lost the ability to walk Suffered unbearable pain After cutting-edge therapies and research, he is now in full remission His message to Lyme patients: “There is ALWAYS hope.”

Send a textIn this episode of Never Been Sicker, Michael Rubino sits down with Scott Forsgren (Better Health Guy) to unpack what actually helps people recover from complex chronic illness. Scott shares his 30-year journey that began with a tick bite, years of severe symptoms, and 45 doctors before finding answers in Lyme and co-infections, and later, mold exposure.Together, they break down why “kill, kill, kill” protocols often fail, why symptoms overlap across mold, Lyme, metals, and immune dysregulation, and what Scott sees as the true foundations of healing: nervous system regulation, mast cell stability, detox and drainage support, and addressing the external environment.They also dig into controversies around urine mycotoxin testing, ERMI interpretation, and why you may improve while living in exposure, but you typically won't fully recover until the environment is addressed.Chapter markers00:00 Intro00:44 Scott's health story begins (tick bite, sudden symptoms)02:47 First real breakthrough: Lyme and co-infections04:51 What Scott would do differently07:14 Moving beyond “kill, kill, kill”10:03 Can symptoms tell you it's mold?12:20 Why we've never been sicker17:00 Biggest mistakes after diagnosis20:36 The foundational steps to healing34:02 Can you heal while living in exposure?38:33 Urine mycotoxin controversy41:58 ERMI, HERTSMI-2, and interpretation50:04 Mycotoxins, spores, fragments, and why “killing” is not enough56:26 The biggest lie: the label59:28 ILADS vs IDSA and what's true on both sides01:03:02 Where to find Scott + final hope message01:06:10 Outro-----------------------------------------------------------------------------------------------

High Yield Bacterial Disease Review:Cholera (Vibrio cholerae) Chlamydia (Chlamydia trachomatis) Gonorrhea (Neisseria gonorrhoeae) Bartonella henselae (Cat scratch disease) Botulism (Clostridium botulinum) Campylobacter (Campylobacter jejuni) Diphtheria (Corynebacterium diphtheriae) Acute Rheumatic fever (Group A Streptococcus) Rocky Mountain spotted fever (Rickettsia rickettsia) Tetanus (Clostridium tetani)Review for your PANCE, PANRE, Eor's, Physician Assistant exams, USMLE, NCLEX, nursing exams.►Support the channel by joining and becoming a member! (Thank you so much!)►Paypal Donation Link: https://bit.ly/3dxmTql (Thank you!)►INSTAGRAM: https://www.instagram.com/cramthepance/►YOUTUBE: https://www.youtube.com/channel/UCZCILePJ-E17txF-ObXlFKwIncluded in review: Cholera (Vibrio cholerae), Chlamydia trachomatis, Gonorrhea (Neisseria gonorrhoeae), Bartonella henselae (Cat scratch disease), Botulism (Clostridium botulinum), Campylobacter (Campylobacter jejuni) Diphtheria (Corynebacterium diphtheriae), Acute Rheumatic fever (Group A Streptococcus), Rocky Mountain spotted fever (Rickettsia rickettsia), Tetanus (Clostridium tetani), Major and Minor Jones criteria, Doxycycline, Azithromycin.Become a supporter of this podcast: https://www.spreaker.com/podcast/cram-the-pance--5520744/support.

Can Lyme disease begin before birth — and could it be driving neurodevelopmental conditions like autism, ADHD, and anxiety?In this episode of Integrative Lyme Solutions, Dr. K is joined by Dr. Somer DelSignore, a leading pediatric integrative clinician, to explore the overlooked science of congenital Lyme and in utero transmission of vector-borne infections. Dr. DelSignore explains how infections such as Borrelia, Bartonella, and Babesia can cross the placenta, disrupt fetal brain development, and silently fuel inflammation that shows up later as behavioral, cognitive, and immune dysfunction.You'll learn why standard TORCH testing fails to catch these infections, what symptoms parents should watch for in infants and children, and how addressing inflammation, infections, and immune imbalance can dramatically improve outcomes. This episode offers critical insight for parents, practitioners, and anyone focused on true prevention and root-cause healing in pediatric Lyme disease.Key Takeaways:0:00 Introduction and Dr. Somer DelSignore's clinical journey3:10 From pediatric ICU to integrative Lyme care6:20 Congenital Lyme: 40 years of overlooked science9:00 Why TORCH testing misses vector-borne infections12:45 Preconception testing and prevention strategies15:30 Why treating Lyme before pregnancy matters18:05 Infant symptoms parents should never ignore21:10 Autism, neuroinflammation, and misdiagnosis24:15 The RESET framework for pediatric healing28:10 What real recovery can look like for childrenResources Mentioned:IGeneX Laboratories – https://igenex.comTLABDX (Babesia & Bartonella testing) – https://www.tlabdx.com/Horowitz/MSIDS 38 point symptom checklist – https://projectlyme.org/msids-questionnaire/IV Ozone Therapy – https://health.clevelandclinic.org/ozone-therapySOT (Supportive Oligonucleotide Therapy) – https://projectlyme.org/supportive-oligonucleotide-therapy-sot-for-lyme/Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions. _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email info@TheKarlfeldtCenter.comCheck out Dr. K's Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

This is episode 76 of the Love, Hope, Lyme podcast. To get your free pdf of "Love, Hope, Lyme: What Family Members, Partners, and Friends Who Love a Chronic Lyme Survivor Need to Know," reach out to Fred Diamond on social media. [NOTE: This podcast does not replace medical treatment. If you struggle with Lyme care, please see a Lyme Literate Medical Doctor.] In this episode of the Love, Hope, Lyme Podcast, Fred Diamond, author of "Love, Hope, Lyme: What Family Members, Partners, and Friends Who Love a Chronic Lyme Survivor" sits down with Dr. Jennifer Miller, who oversees clinical and scientific operations at Galaxy Diagnostics, for one of the most important conversations we've ever had about Lyme disease. We discuss the basics. Not just what Lyme does, but why it happens in the first place. Dr. Miller brings decades of deep scientific experience studying Borrelia burgdorferi and explains: ✅ How ticks actually become infected ✅ Why nymph ("seed") ticks are the biggest threat to humans ✅ What happens biologically inside the tick and inside your body ✅ Why Borrelia is so hard for the immune system (and antibiotics) to find ✅ How co-infections like Bartonella and Babesia complicate diagnosis and recovery ✅ Why some people develop neurological symptoms while others don't ✅ Why today's antibody tests often miss active infections and how Galaxy is working on direct detection methods to change the standard of care We also talk about:

Why do so many Lyme patients stay sick — even after treating infections, detoxing, and “doing everything right”?In this episode of Integrative Lyme Solutions, Dr. K sits down with functional and environmental medicine pioneer Dr. Kelly McCann to explore why Lyme disease, mold toxicity, and Mast Cell Activation Syndrome (MCAS) are rarely just infections — and why true healing requires addressing the terrain of the body, nervous system, emotions, and spirit. Drawing from her own journey through mold illness and Lyme disease, Dr. McCann explains how immune dysregulation, trauma, limbic system activation, and cell membrane damage keep patients stuck in chronic illness.This conversation dives deep into mast cell activation, mold exposure, Bartonella, phosphatidylcholine therapy, biofilms, nervous system regulation, emotional trauma, spirituality, and why symptoms are not betrayals — but messages. If you've been gaslit, dismissed, or feel like your body is working against you, this episode offers validation, insight, and a radically different way to understand Lyme healing.Key Takeaways:0:00 Introduction and Dr. Kelly McCann's personal healing journey3:00 Mold exposure as a hidden driver of chronic illness6:20 Lyme, Bartonella, and the overlap with mast cell activation9:30 Why siloed medicine fails complex chronic disease patients11:40 Phosphatidylcholine and cell membrane repair explained13:50 When antimicrobial treatment stalls, look beyond infections16:50 Mast cell activation, trauma, and nervous system dysregulation18:40 The limbic system's role in chronic illness21:10 Emotional trauma, immune boundaries, and people-pleasing24:00 Language, identity, and separating yourself from disease26:10 Terrain theory and why healing requires self-honoring choices29:00 Illness as an invitation, not a punishmentResources Mentioned:Dr. Kelly McCann – https://drkellymccann.comThe Spring Center – https://thespringcenter.comThe Unforgetting Project – https://unforgettingproject.comMicroGen DX (Next Generation Sequencing) – https://microgendx.comByron White Formulas – https://byronwhiteformulas.com _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email info@TheKarlfeldtCenter.comCheck out Dr. K's Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

In this powerful and deeply moving episode of the Tick Boot Camp Podcast, we sit down with Julia Bruzzese, a 22-year-old Lyme disease survivor, disability advocate, and future physician whose life was forever changed by an untreated tick bite in childhood. After developing a classic bull's-eye rash at age 9, Julia went undiagnosed for nearly two years, despite textbook symptoms of Lyme disease. By age 11, she experienced a catastrophic neurological decline that left her paraplegic and wheelchair-bound. Over the next decade, Julia saw more than 100 doctors, endured profound medical gaslighting, and navigated an exhausting journey through antibiotics, IVIG, IV antibiotics, plasmapheresis, stem cells, ozone therapy, and integrative care. Julia's story became internationally known after a moment with Pope Francis on the JFK airport tarmac went viral in 2015—an event that opened doors to care, advocacy, and awareness. She later became the emotional centerpiece of the award-winning documentary The Quiet Epidemic, appeared at New York Fashion Week as a Lyme disease advocate, and was profiled by renowned journalist Mary Beth Pfeiffer. Today, Julia is finishing her undergraduate degree and has been accepted into medical school, determined to become the kind of doctor she needed when the system failed her. This episode is a masterclass in: Pediatric Lyme disease Medical gaslighting vs. lack of education Clinical diagnosis vs. unreliable testing The patient-doctor relationship Chronic illness, disability, and purpose Why Lyme disease changes lives—and why early treatment matters Childhood Lyme Disease & Missed Diagnosis Tick bite and bull's-eye rash dismissed at age 9 Two years of worsening symptoms labeled as “growing pains,” viruses, or psychological Why early Lyme treatment saves lives Neurological Collapse & Hospital Trauma Sudden onset of paralysis, vision loss, fevers, hair loss, and weakness at age 11 Over 100 doctors and repeated hospitalizations Being accused of malingering and conversion disorder The devastating impact of medical disbelief on children The Quiet Epidemic Documentary How Julia became the heart of the film at age 12 Why she initially hesitated to share her story The emotional impact of seeing her illness reflected on screen How the documentary helps families explain Lyme disease to others Meeting Pope Francis & Global Awareness How a school principal secured last-minute tickets The Pope walks directly to Julia's wheelchair The moment that changed everything Media coverage that led to access to lifesaving care Treatment Journey Lyme-literate diagnosis by NP Somer DelSignore Oral and IV antibiotics IVIG (including under-dosing issues) Plasmapheresis POTS, Babesia, Bartonella, and autoimmune complications Stem cell therapy abroad Ozone and integrative protocols Why there is no single silver bullet for Lyme disease The Medical System & Lyme Denial Why doctors often say “it's all in your head” The difference between malice and lack of training How medical education fails chronic illness patients Fear of insurance companies, lawsuits, and “accepted guidelines” Why Lyme is a clinical diagnosis, not a test result Reframing “Medical Gaslighting” Why anger is understandable—but not always healing How patients and doctors can become better partners Understanding doctors' limitations without excusing harm Advocacy with clarity, not hostility Disability, Identity & Resilience Navigating life and education as a wheelchair user Accommodations, accessibility, and invisible illness “I have Lyme. I am not Lyme.” Learning when to rest, when to fight, and when to live Becoming the Doctor She Needed Working as a medical assistant and hospital volunteer in a wheelchair Applying to and being accepted into medical school Becoming the first wheelchair-using medical student at her institution Why lived experience belongs in medicine Medical Malpractice Lawsuit Lawsuit filed in NYC (March 2021) against multiple doctors and hospitals Failure to diagnose and treat Lyme disease despite clear evidence Why Lyme malpractice cases are rare—and necessary Seeking accountability, not revenge Purpose, Faith & Meaning From “Why me?” to “Why not me?” How suffering clarified her calling The role of faith, family, and community Why Julia wouldn't give this journey back—even now Memorable Quotes “I was criminalized as an eleven-year-old child for being sick.” “It actually was in my head—the bacteria was in my brain.” “I have Lyme disease. I am not Lyme disease.” “There is no silver bullet for Lyme. Healing is trial and error.” “I wouldn't be who I am—or know my purpose—without this journey.” Why This Episode Matters This episode is essential listening for: Parents of children with unexplained symptoms Lyme disease and chronic illness patients Medical professionals and students Advocates fighting for better diagnostics and care Anyone who has ever felt dismissed, unseen, or unheard in healthcare Julia Bruzzese's story is not just about Lyme disease—it's about truth, resilience, accountability, and hope.

The Great Mimicker: Is It Lyme Disease or Something Else? | Podcast #469

In this powerful episode, Tick Boot Camp Podcast interviews Dr. Karolina Praskeviciute (“Dr. Pras”), a multilingual, European-trained medical doctor who has lived in Lithuania, Hong Kong, London, and the United States, traveled to 89 countries, and now uses her global experience to understand chronic illness from a unique vantage point. Dr. Pras shares her deeply personal story of lifelong unexplained symptoms, childhood mold exposure, a bull's-eye rash at age 15, and a medical system unequipped to recognize chronic tick-borne illness. After a devastating case of early COVID-19 in February 2020, her immune system collapsed, triggering full-blown Lyme disease, Babesia, Bartonella, tick-borne relapsing fever, MCAS, and Chronic Inflammatory Response Syndrome (CIRS). This conversation bridges both sides of medicine—Western and functional—and explores how chronic illness forced Dr. Pras to reevaluate everything she learned as a third-generation physician. She now brings a rare, dual perspective as both clinician and patient. Key Topics Covered ➤ Growing up in Lithuania: culture, safety, freedom & early mold exposure She describes an independent childhood surrounded by nature—but also living in a poorly insulated home with significant hidden mold that triggered early allergies, stomach pain, nosebleeds, and metallic taste. ➤ Medical school awakening: Why Western medicine failed her symptoms Despite coming from a family of doctors, she noticed early on that conventional medicine couldn't explain many of her symptoms—and she witnessed firsthand how chronic illness is minimized, dismissed, or mislabeled. ➤ The first tick bite at 15 & the bull's-eye rash ignored by doctors Despite developing textbook erythema migrans, pediatricians refused treatment. Her mother initiated a short doxycycline course on her own—far too short to prevent chronic Lyme. ➤ Traveling the world & accumulating exposures After living and working across continents, she now believes different strains, microbes, and environmental factors layered into the perfect storm. ➤ Long COVID as the breaking point Like many chronically ill patients, COVID destabilized everything: massive immune dysregulation nonstop inflammation MCAS flares worsening neurological symptoms Lyme and Babesia fully activating ➤ Mold + Lyme + Long COVID = The Perfect Storm Her CIRS diagnosis revealed why she never recovered even after leaving mold exposure—and why immune dysfunction made Lyme treatment far more complex. ➤ Her diagnostic breakthrough with IGeneX After repeated false-negative Western blots, specialty testing finally uncovered: Lyme Babesia Bartonella Tick-borne relapsing fever (TBRF) Immune activation on FISH testing ➤ Treatment: Herbs, LymeStop, detox, keto, and functional medicine Her current regimen includes: Houttuynia (major reduction in joint pain within 1 week) Cryptolepis (powerful antimicrobial requiring slow titration) Custom herbal protocols (single-herb tinctures) HBOT INUSpheresis Light sauna Gentle lymphatic drainage Vagus nerve support Journaling & limbic system retraining Strict ketogenic diet after a 7-day fast dramatically reduced inflammation She also discusses the risks of Botox, fillers, tattoos, and skincare toxins for chronically ill patients. ➤ Nervous system healing as the foundation of recovery She explains why vagus nerve work and limbic retraining may fail if patients are still in toxin exposure (like mold or endotoxins)—a vital distinction rarely discussed. ➤ Becoming a doctor who understands chronic illness from both sides This episode explores: medical defensiveness gaslighting vs unhealthy doctor-patient dynamics why patients must be empowered, not dismissed why doctors also need compassion and realistic expectations how her future clinical practice will integrate empathy, functional medicine, and lived experience Top Quotes From Dr. Pras “I dismissed my own symptoms because I was trained to believe nothing was wrong unless labs proved it.” “Mold was the silent force that weakened my system long before Lyme took over.” “Healing is not linear. Some days it feels like I'm starting over, but I always come back stronger.” “Doctors have tools—but without a healthy doctor-patient relationship, those tools don't work.” “I can help others now because I know when to push and when to pull back. Lived experience matters.” Where to Find Dr. Karolina Pras Instagram: @drkaromd Email: drkaro@healthkonsultant.com (“consultant” spelled with a K)

Dr. Deb Muth 0:03Today’s guest is someone I’m honored to call both a friend and a mentor, and one of the most trusted voices in medicine for patients with complex chronic illness. Dr. Neal Nathan is a board certified family physician who has spent decades caring for patients who don’t fit neatly into diagnostic boxes. Patients with mold related illnesses, Lyme disease, mast cell activation, and profound nervous system dysregulation. These are the patients who are often told their labs are normal and their symptoms are anxiety or that nothing more can be done. Instead of dismissing them, Dr. Nathan listened and he asked better questions. His work, including his landmark book, Toxic, has helped thousands of people finally feel seen, believed, and understood, and more importantly, has given them a path forward when medicine failed them. This conversation is for anyone who reacts to supplements or medications, for anyone who has gotten worse instead of better with treatment, and for anyone who knows their body that something deeper is going on, even if they’ve been told otherwise. Dr. Nathan, I’m deeply grateful for your mentorship, your integrity, and the way you continue to advocate for the most vulnerable patients. I’m so glad to have you here today. And before we begin, grab a cup of coffee, tea, or whatever grounds you, because this is the conversation you’ll want to settle into. Now, before we go onto this conversation, we need to hear from our sponsors. So give us just a quick moment and then Dr. Nathan and I are going to dive in to his story and how this all started for him and leave you with some nuggets of wisdom that you can help yourself with. Ladies, it’s time to reignite your vitality. Primal Queen supplements are clean, powerful formulas made for women like you who want balance, strength, and energy that lasts. Get 25% off@primalqueen.com Serenity Health that’s PrimalQueen.com Serenity Health because every queen deserves to feel in her prime the right places and then we can get started. All right? So, Dr. Nathan, like I said, I’m so excited to have you here today. Tell us a little bit about how did you start your career? Because you didn’t intend to work with the most complex and sensitive patients, I’m sure when you started out. But what did you notice early on that made you realize medicine was missing something? Neil Nathan MD3:03You know, Deb, actually, I did start out wanting to work with the most complicated cases. My delusional fantasy when I started was I wanted to help every single person who walked into my office. And so when I left medical school, I realized pretty quickly that the tools that I learned there were not adequate to do That I needed to learn more. So I started on a passionate journey of discovery, if you will, in which I started studying with anyone who had anything interesting about healing to talk about. And I want to emphasize that I was interested in healing, not in what I’ll call medical technology. So medical school taught me to be a good medical technologist, but it didn’t teach me about healing. I graduated a long time ago. I graduated from Medical School in 1971. And the word holistic wasn’t even a word back in those days, but that’s what I was looking for over many, many years. I studied osteopathic manipulation, homeopathy, therapeutic touch, emotional release techniques, hypnosis. If it’s weird, I probably have studied it at some point. I wasted some weekends studying things that I don’t think were particularly valuable. And I’ve had some remarkable experiences with true healers that taught me how to expand my understanding of what healing really meant. So early on, when I first started practice, I would invite my colleagues to send me their most complicated patients because that was my learning. That makes me weird. I know that. I love some problem solving. You know, I’m the kind of person who I get up in the morning and I do all of the New York Times kinds of puzzles. That’s. That’s my brain wake up call. So actually I did invite my colleagues to send me their complicated patients, and they did. So, I mean, they were thrilled to have me in the community because these were people they didn’t know what to do with. And I was happy as a clam with all these complicated things that I had no idea what to do with. But it pushed me to keep learning more, to keep searching for this person’s answer. And this person’s answer, that constant question is, what am I missing? What is it that I don’t know or understand? What questions am I not asking this person that would help me to figure it out? So sorry for the long winded digression. Dr. Deb Muth 6:14No, I’m glad you shared that. I’m very similar to you. I didn’t seek out working with the most complex, but as I started that, I was always very curious as well. So I was the same as you. Every weekend I would learn something and hypnosis and naturopathic medicine, homeopathy, and all these quote unquote weird things, right? And there’s always a pearl that you learn from something. You never not learn anything, but some of it, you kind of take or leave or integrate or not. And, and I think it, it makes you a better Practitioner, because you have all these tools in your toolbox for helping people that nobody else has been able to help. And. And it’s just kind of fun learning. I mean, I’m kind of a geek that way too. I like to learn all those things. Neil Nathan MD7:00Learning is my passion. One of my greatest joys in life is going to a medical meeting and getting a pearl. Literally. I’m not one of these people at medical meetings that have a computer in front of me listening. And I have a pad of paper and I’m writing down ideas next to people that I’m working with. So that, oh, let’s bring this up for these people. Let’s bring this up for these people. So it’s like, oh, great. Can’t get right back to the office on Monday so I can start, have some new ideas about what I’m missing. Dr. Deb Muth 7:38Yeah, I do the same thing. I have my pad of paper and I do the same thing. And as I hear something, I’m thinking about a person that’s in my office that I haven’t been able to help, or we’ve been stuck on something, and I’m like, oh, there’s a new thing we can try. And it’s so exciting. I love that. Let me ask you this. Was there a time when you finally thought, like, if I don’t listen to these patients differently, they might not ever get better? Neil Nathan MD8:04That’s a very complicated question. The people that I was treating that weren’t getting better were the ones that got my greatest attention. And one of the questions that constantly troubled me still does is, is this person not getting better because of some feature of themselves, or is it because of something that I don’t know? So I’ve wrestled with that for a very long time. My answer to it now is, For a long time, I’ve been able to see what I will call the light in a person. Call it a healing spark and energy. It isn’t truly light. There’s just something about that person when I work with them where I know this person will get well if I stick with them long enough. And then when I don’t get that, I don’t think I’ve helped any of those people over the years. Yeah, so it was a very long process of really not helping people for five years daily. And I would. I would ask those patients, I would say, you know, I haven’t helped you. We’ve been doing this for a very long time. Why are you still here? And they would say, because you care. And I would. Back when I was Younger, that was enough for me to go. That’s true. Okay, I’ll keep working at it. But as I’ve gotten older, caring isn’t enough. It’s. I’m not sure I’m the right person for you. And so as I’ve gotten older, when I don’t see that spark, when I don’t get that sense of someone, I’m more inclined early on in the relationship to tell them I’m not the right person for you. Yeah, you know, see if you can find someone else who can understand what you’re going through and help you. Because I, I’m not it. Dr. Deb Muth 10:16Yeah, you, you kind of know that you can help them or not. Yeah. Neil Nathan MD10:21I don’t know how to define that sense, but it’s very clear to me. I call it like seeing the inner light of another being. If it’s not there, and maybe it’s not there for me to see as opposed to someone else can see it. Dr. Deb Muth 10:41That’s interesting. So you’re known for working with patients who are highly reactive. They don’t tolerate supplements, a lot of times medications, or even some of your most gentlest protocols. Why are these patients so often misunderstood? Neil Nathan MD 10:59Because they appear to their family and to many other physicians to be so sensitive that the thought process of families and other physicians is often. Nobody’s that sensitive. This has got to be in your head. And that is what is conveyed to those patients. And they’re told it’s gotta be in your head. Go see a psychiatrist or a therapist. But I can’t help you. And unfortunately, we have learned in the last 20 years a great deal about, is making our patients so sensitive. It is a true reaction of their nervous system and immune system, and it is in response to various medical conditions they have. So again, as we’ve been talking about, those were the people that got sent to me for many years. And I, I have never believed that the majority of any. Anything that someone has experienced is in their head. Yeah, Almost everything I look at is real. I may not understand what is causing it, but for me, doubting a patient’s experience is not something I’ve ever done. And that’s what’s helped fuel what I’ve learned and what you learned over the year. That, okay, if this is real, and it is, I’m sure it is, the person in front of me looks like a straight shooter. They’re not hyper reactive. They’re not going off the deep end talking about it and talking about it very straightforwardly. And I’ve got these symptoms. I’VE got this, I’ve got this. And it’s really making my life miserable. Okay, what’s causing that? So I began to work with what we now call very sensitive patients and figuring out what caused that. So over the years, I think we have names for this in medicine. Sometimes we call this multiple chemical sensitivity. People who will go to be walking down the street and someone will walk past them wearing a particular scent or perfume and they will literally fall to the ground or go brain dead or can’t think straight or even have some neurological symptoms. And I’ve seen that happen in my office. I’ve seen patients walking down the hall and having a staff member who had washed their clothes and tied walk past them. And I literally watched them fall on the floor. And it’s like, this is not psychological. This is someone who is reacting to the chemical that they are being exposed to and this is the effect it’s having on them. And so eventually it became clear that all forms of sensitivity, sensitivity to light, sound, chemicals, smells, food, EMFs, touch, were really being triggered by a limbic system that was unhappy. We began to learn about limbic issues before that. Give you a short history of it. I have discovered something called low dose immunotherapy different by Butch Schrader. And there was a long three year period of if someone stuck with it. If I used those materials over time, a lot of my chemically sensitive people would get better. It was the only tool I had back then. Dr. Deb Muth 14:41Yeah. Neil Nathan MD 14:42)Then, I don’t know, 15 years ago I discovered Annie Hopper’s work with dynamic neural retraining. And when I added that to what people were doing, that’s when I had my, ah, this is an Olympic system issue. And this is something we can reboot. And since then, many other people have limbic rebooting programs which are quite excellent and useful. Now I helped a lot of people at that point and it wasn’t until I stumbled on Stephen Porges work with the vagal system with this concept of polyvagal theory that I realized that the two areas of the brain that are monitoring that person’s environment, internal and external, for safety, are the limbic and the vagal systems combined. So when I started adding vagal strategies to the limbic strategies, I helped even more people. And then the first, the third piece of this trifecta was 2016 when Larry Afron wrote his book Don’t Never Bet Against Occam, in which he began our understanding of mast cell activation. And when I read his book, it was like, oh, big piece of the puzzle. And then we realized that those three things. And there’s more, but those three things were treated, Would help the vast majority of our sensitive patients regain their health and regain their equilibrium. This is not psychological. This is really treatable. Dr. Deb Muth 16:19Yeah, I’ve noticed the same thing in my practice and followed very similar paths. As you started out with ldi and lda, and then the vagus nerve things have been by far. I think if I look back, the vagus nerve work has been the biggest changer in our practice as well. I mean, all of the things help, but, like, I can give somebody a vagus nerve stimulator today, and within 30 days, 90% of their symptoms are better. And that just kind of blows my mind. It’s like I’ve never had a tool in my toolbox that has worked that well and that quickly. So. So it really is making a big difference. And I, too, was trained way back in the late 90s with multiple chemical sensitivity people. And some of those clients that I inherited from my mentor are still around. And, you know, they still can’t function at all. They’re wearing gas masks. They can’t leave their house. You know, any smells that even come in without them opening the windows, they are stuck. And no matter what you do, it’s just a challenge. Nothing works for them. And it’s a very sad life that they have to live. Neil Nathan MD 17:30Well, let’s add to that story that you can give people limbic vagal and mast cell treatments, and it’ll really work well to help them, but you need to look deeper, which is what is causing mass cell issues. And in my experience, mold toxicity is by far the number one and various components of lyme disease is a second one, and then a variety of other environmental toxins, infections, and things like that may trigger for some, but you’ve got to go back and get to the cause or else. Dr. Deb Muth 18:12Yeah, nothing works. Neil Nathan MD 18:13You can make them better, but you can’t really get them. Well, you get rid of the cause, and people can completely differently life back. Dr. Deb Muth (18:20-18:21)Yeah. Neil Nathan MD 18:22One of my frustrations with the mast cell world is after Larry efferent’s book came out, it changed people’s consciousness about mast cell activation. Something genetically rare to something which we now know. It affects 17% of the population, so not rare at all. But the clinics that are popping up to do it, and now in every major medical center of the country has a mast cell clinic. But number one, they rely completely on testing to make the diagnosis, and testing is notoriously inaccurate. And second, they just aren’t aware that you gotta get cause. So they’re helping people, but they’re not curing people because they’re not looking for cause. Dr. Deb Muth 19:13Yeah. And if they’re helping people, it’s on a minimal level, in my experience. They’re. You know, most of the patients that we see that have been at those clinics have been dismissed. Once again, told that because the testing isn’t positive and they’ve only done it once, that they don’t have this. But yet they fit all of the pictures. And then when you start digging, you start realizing they really do have mast cell, and. And you can find the answers for it for them. Neil Nathan MD 19:40Yeah. Dr. Deb Muth 19:41Why do you think mold remains so unrecognized in conventional medicine? Neil Nathan MD 19:48Interesting question. You know, I started writing a book chapter on the history of mold toxicity, our understanding of mold toxicity. And it’s. It’s fascinating to me. The mold toxicity is described in the Bible as a fairly long passage in Leviticus where it talks about that. So it’s not like it’s unknown to the universe, but largely, it’s remained undiscussed. Most people are aware of mold allergy. We’ve been treating mold allergy for decades. That we accept fully. I think the answer to your question lies in history a little bit. And I didn’t know this until I started kind of digging into it. There was an episode in the 70s in which a large number of school children in Cleveland, Ohio, got sick, and public health authorities attributed it to mold. About a year or two later, it was discovered that they. The H VAC system in the school had Legionella. Legionnaires disease. And it was then decided that, no, it wasn’t mold, it was legionnaires. And then a number of articles began appearing in the medical journals. Their names were literally mold. The hoax of mold toxicity. And that consciousness pervaded for 20, 30 years where people were reading these articles in which they were being told that mold toxicity was a hoax. That’s a strong word. And it took papers after papers after papers published in all kinds of medical journals, which were began to say, this is very real. This is symptoms that. That we see. It wasn’t until 2003, when Michael Gray and his team published a series of papers showing that these widespread symptoms, which we now recognize as mold toxicity, was real and directly attributed to mold. Now, keep in mind, we didn’t even have a test for mold at that point. Dr. Deb Muth 22:10Right. Neil Nathan MD 22:12So you could say this is mold toxin, because this person was. Well, they went into a moldy environment, they got sick, they went out of the moldy environment. They got well again, but we didn’t have treatments. We didn’t have a test for it. Historically, people were suspicious. Not very scientific. 2005, Richard Shoemaker wrote his book mole warriors, which really began to popularize the concept of this was a real thing. And in it, Ritchie talked about his markers and the visual contrast test. Now, these were not specific for mold, but they strongly, at least implicated that. Now, we had a test that could be helpful. So it wasn’t really until about 2010 that the first urine mycotoxin test came on the market. And at that point, we. We really could tell a person, you’ve got these symptoms, you’ve been living in mold. And now we have a test that shows you have mycotoxins in your urine. Now, it’s not like it’s a theory. It’s coming out of your body. That has furthered it, but not yet in the consciousness of the medical profession at large. As I’m sure you know, the history of medicine, in fact, the history of science, is that new ideas take 20 plus years to really be accepted by the profession. A new drug, a new technology is accepted very quickly because there’s an economic push to it. There’s no economic push to a new idea. So we’re still in the throes of some of us who work in the field. People say there’s no published data that really prove that this exists. And we’re working on that. As you know, we’re working on getting the papers published, but again, working on this history of molotoxism, There are actually hundreds and hundreds and hundreds of papers in the medical literature which really attest to the fact that this is a reality. It’s just that you and I are the only ones reading these papers. Dr. Deb Muth 24:33Yeah, we’re the only ones that care. Yeah. What would acknowledging mold actually forced medicine and the institutions to confront? Neil Nathan MD 24:44First of all, many medical offices and. Dr. Deb Muth 24:47Hospitals are molding, very much so. Neil Nathan MD 24:51And nobody wants to deal with that. It’s expensive. It’s difficult to truly get mold out of a building when it’s there. And so there’s a huge economic push to not acknowledge mold toxicity as an entity. The whole building industry doesn’t want to deal with it. Yes. It is estimated by the federal government that 47% of all molds have visible or smellable mold in them. It’s not like it’s rare. Not everyone’s going to get sick from it. But if your immune system takes a hit from anything and it loses containment over that mold, then you will take a hit from it. And it is also estimated that at least at this moment, 10 million Americans are suffering with some degree of mold toxicity and don’t even have a clue that that’s a real thing and that it can be both diagnosed and treated successfully. Dr. Deb Muth 25:51Yeah, it’s so hard. Like so many of the patients that we see, mold is never on their radar when they come to us. You know, Lyme disease is never on their radar when they come to us. And many of our patients have both. And the argument of there’s no way I could have, you know, mold exposure until you start digging back into their history a little bit. And then they’ll say, well, yeah, grandma’s house smelled and you know, I live in a hundred year old house, but it’s been completely renovated. And until you start having these conversations and really talking about it, people don’t have a clue that these things could make them sick. Or they, you know, I have a lot of clients that renovate houses for a living or that’s, you know, their hobby. And they go in and they renovate these houses and they’ve never worn appropriate equipment to protect themselves and, and then they’re sick 10, 15 years later. But don’t really understand why. Neil Nathan MD 26:47Yeah, from my perspective, it’s about how robust the immune system is. Dr. Deb Muth 26:51Yeah. Neil Nathan MD 26:52That if your immune system is robust, and this is true for Lyme as well as molecules, you could be bitten by a tick, you may have a Lyme or a co infection of Lyme like Bartonella rubesia in your body, or you could be exposed to mold, you could be living in a moldy environment, and your immune system will allow you to function at a high level for a while if your immune system takes a hit. Now the hit recently, big time, was Covid that unmasked Lyme and mold for a lot of people and a lot of people who think they have long whole Covid really have unmasked that they have Lyme and mold toxicity. That’s a whole other subject here. But menopause, childbirth, surgical procedure, any severe infection, any intense emotional reaction, death of a loved one, any of these can weaken the immune system. And then what is already there is no longer contained and we are off to the races of severely impaired health. Dr. Deb Muth 28:02Yeah, that’s what it did for me. I got sick with COVID and maybe about six, eight months later, I started to express neurological symptoms that looked like Ms. And actually had the diagnosis of Ms. But knowing what I know, I said, you know what? Ms. Is something else. Until proven otherwise in my book. And so because I had the knowledge that I did, I went and did all the Lyme testing and the mold testing and hit the trifecta of everything. Lyme co infections, mold, viruses. I just had everything. And as I started down that path of trying to clean it all up, all of my symptoms started to disappear. And certainly it wasn’t as easy as it sounds, and it wasn’t as quick. And I felt a lot worse before I felt better, as most of our clients do. But I think that I’m not the only person that this has happened to. And I think a lot of people get misdiagnosed just simply because nobody’s looking for the other problems that you and I look for and that we know of. And that’s one of the ways our medical system fails the clients they work with. Unfortunately. Neil Nathan MD 29:12One of the things that I teach and want people to be aware of is any specialist who makes the diagnosis that includes the word atypical. So atypical ms, atypical Parkinson’s, atypical Alzheimer’s, atypical rheumatoid arthritis, whatever it is, if that’s the word. What they’re saying is this has feedback features of this illness, but doesn’t really match what I see every day in my office. And when I hear the word atypical, I say, please look for mold, please look for Lyme. Because that is often the case here. Dr. Deb Muth 29:51Yeah, oftentimes it is. You also teach that when patients get worse under treatment, it doesn’t mean they’re failing. It means the treatment might not be appropriate for their psychology. Can you explain that a little bit? Neil Nathan MD 30:05Yeah. I think that many people start understanding about things like Lyme or mold and don’t really have the bigger picture. And so they will jump in with aggressive treatments in people who aren’t really ready for that degree of aggressive treatment. And here we’re going to come back to, if someone’s living vagal and mast cell systems are dysfunctional and not working properly, it is highly likely they won’t be able to take normal doses of the binders we use for mold, or to take antifungals or to take the antibiotics we need for Lyme disease. It’s not that they don’t want to. They can’t. And so what I see is not understanding what you need to do, in what order. If you do it in the right order, you’ll help the vast majority of people you’re working with. And again, that trifecta of limbic vaginal, mast Cell is one piece that a lot of people don’t address. And again, order matters. For example, in the mold world, some people have learned that, oh, I’ll need to give people antifungals to get this mold and Candida out of their body. But if you do that and you don’t have binders on board, there’s a very high risk that you’re going to cause a severe die off and make people really miserable. I remember when we kind of first started this, I was working with Joe Brewer, who’s an infectious disease specialist from Kansas City. And Joe wrote some of the earlier papers on this particular subject. And I was doing, I had a radio show at that point and Joe was on and we were talking about mold toxicity and how we treat it and what we did. And he mentioned that about 40% of his patients had this really nasty die off. And I went, I almost never see a die off. And so when we got off the program, we sat down and tried to compare notes about, okay, what am I doing differently than you, that I’m not getting the die off. And Joe, as an infectious disease specialist would go quickly to his antifungals. And yes, he put people on binders, but he also simultaneously put the lungs in pretty heavy doing antifungal. They got a nasty diure. I never put people in antifungals until their binders were up and running. So from my way of thinking about it, if you use any antifungal, they all work by punching holes in the cell wall of either a mold or a candida organism, killing it. However, by punching holes in it, what’s in that cell leaks out. And that includes mycotoxins. So. So you’re literally, if you’re using it aggressively, you can literally flood the body with mycotoxins. And if you don’t have the binders on board to mop it up, there’s a high risk that you’re gonna be pretty miserable. Cause you’re literally more toxic. Dr. Deb Muth 33:18Yeah, I remember in the early 2000s when they were teaching, if you’re not getting somebody to have that die off reaction, that quote unquote, herx reaction, then you’re not doing your job, you’re not giving them enough. And we would have clients that would come in and say, I’m not herxing. You’re not doing enough for me. And we were always the ones that are saying, you don’t have to hurt to get rid of this thing. I’m a naturopath too. And so preserving the adrenal Function was always very important to us. And we were like, if we cause you to hurts like that, now we’re depleting the adrenal system. We’re creating more problems that we’re gonna have to fix on the backside. And that was the narrative that was being taught back then. And I’m glad that’s not the narrative that’s being taught today, for sure. But people don’t understand. Like you said, you’re more toxic at this point, and creating more toxicity isn’t what we want to do. Neil Nathan MD 34:12It’s not good for healing. Kind of intuitively obvious, but you’re right. Back in the early days, we were taught that just to put a spin, I’ll call it on a nasty Herc’s reaction. Oh, great, we’re killing those little microbes. This is fabulous. Yep. I mean, that’s how we spun it back then. And currently I can’t say that some Lyme literate doctors still believe that, but most of us have realized that. No, that means we’re killing him too quickly. We need to modify what we’re doing so that we are killing it, but not at a rate that our patient is getting worse. Dr. Deb Muth 34:59Yeah, I always tell people we want to kill the bug, but we don’t want to make you feel like we’re killing you at the same time, because that’s what’s going to happen if we’re not careful. So, yeah, how does trauma and emotional or physical trauma and abuse and chronic illness, how do they all reinforce each other? Neil Nathan MD 35:24Our limbic systems have been trying to keep us safe since we were in our mother’s uterus. By again scrutinizing the stimuli we’re being exposed to from the perspective of safety. So none of us have had perfect childhoods. Yeah, some older than others. But depending on what you had in your childhood, maybe you had recurrent ear or throat infections and took lots of antibiotics. Or maybe you needed surgeries. Or maybe you had parents who were both working and not particularly available to you. Or maybe you had abusive parents in any way possible. But through your whole childhood experience, your limbic system is really going okay. This isn’t safe. This is not good for me. This is not right. And becoming more and more hyper vigilant to really be aware of that so it can try to keep us safe, which is okay. Maybe my parent was an alcoholic and okay, they’re coming in now. I’m going to make myself scarce. My limbic system is going to tell you, get out of here. Don’t put yourself in harm’s. Way, if that’s the case. And then as we go through our lives, more things occur. We have heartbreak when we’re teenagers, and we have difficulties with work or bosses or other things. Each insult of safety to us helps to create a limbic system that is more and more hypervigilant. So if you then have a trauma of any kind, it’s kind of like the straw that breaks the camel’s back at that point. And that could be mold toxicity, that could be Covid, that could be the loss of a loved one, that could be a betrayal of some point, any number of things, once that happens. Now that limbic system is super hypervigilant. Now, what that means is, symptomatically for people is we’re going to have symptoms in two main categories. Not to make us sick, but to warn us from our limbic system that, hey, this isn’t safe for you. You got to get into a safe place here. And those symptoms are in the category of emotion and sensitivity. So with any of our patients that we see, if they have become more and more anxious patients, panic, depressed, ocd, mood swings, depersonalization, derealization, that’s all limbic. And if they have any increase in sensitivity to light, sound, chemicals, smell, food, touch, EMFs, limbic. So most of our patients have gotten to that place. And as I’ve said, the vagal system comes along with the limbic system because it does the same job. Those symptoms are a little different. The vagal system controls the autonomic nervous system, and so things like temperature, dysregulation, pots, blood pressure, palpitations. The vagus nerve also controls almost all gastrointestinal function. So almost any symptom in the GI tract is going to have a vagal piece to it. Gas, bloating, distension, reflux, abdominal pain, constipation, diarrhea. So those are common symptoms in our patients. And it helps us to tease it apart that we can literally tell them these are symptoms of vagal dysfunction. These are symptoms of limbic dysfunction. And I hope I’m answering your question, which is, how does this evolve? It evolves throughout our whole life, and then eventually we get to the point where our limbic system is overwhelmed. And here’s the good news. We can treat this. We can fix it. We have various programs. And honestly, Deb, I believe that every man, woman and child on this planet needs limbic retraining, or at least limbic work. Co did a real number on the whole planet. Yeah, most people live in some degree of fear From a wide variety of causes. And we don’t have to live in fear. We don’t have to let us hurt us, but we do need to recognize that it is limbic, it is vagal, and we can do something about it. Dr. Deb Muth 39:58Yeah, that’s an exciting time for us, I think. You know, I. I agree. Like, the last couple of years have been very traumatic for a lot of people. Our young kids that were traumatized in school, their parents, the grandparents. I mean, everybody has gone through some kind of anxiety or fear around what’s happened in the last few years, and not to mention all the things that they’ve lived with their whole lives. And this just kind of came to a head and I think broke open for a lot of people that were suppressing their feelings up until this point. And it. It just was the perfect storm for a lot of people, unfortunately. And there’s a lot of people that can’t get over the trauma that’s occurred. The lying amongst the government and our families, how we treated each other and pushed each other aside and, you know, broken families apart because of their belief systems. It really did a number on people, and they’re really struggling to get back. Back for sure. Neil Nathan MD 40:56Yeah, we’re in complete agreement here. Dr. Deb Muth 40:59Yeah. Yeah. So many of our listeners, especially women, have been told their symptoms are anxiety or stress or quote, unquote, just hormonal. Right. And from your perspective, what damage does that kind of dismissal cause for people? Neil Nathan MD 41:16We have a fancy word for that, which is iatrogenic illness. Translation is your doctor is making you sick by treating you inappropriately, not making the right diagnosis and not honoring what you’re experiencing. There’s actually a new word that I’ve recently heard called medical gaslighting, in which you describe something to your doctor and he goes, no, this is in your head. There’s nothing really physically wrong with you, and you know that. No, no, no, no, no. I might be a little bit stressed by it, but something else is going on in my body. And they’re telling you, no, we tested you. Usually those testings involve doing a blood count and a chemistry profile, and that’s it. Those tests will not reveal the kinds of things we’re talking about because you’re not looking for the right thing. So it is really common for our patients to have been told that there’s nothing wrong with you. You need to see a psychiatrist because they don’t know enough to understand that the symptoms you’re describing, if you understood what you’re looking at, are very clear manifestations of Things. Things like mold toxicity and Lyme disease, chronic viral infections, a variety of other things. But your doctor has to know this in order to happen. And this is a failure of medical education. So if my message to everybody always is never doubt yourself or what you’re experiencing, it’s real, there’s never a reason to doubt that. If the people around you aren’t believing, you find someone who does. And again, to augment this, part of the problem is if families accompany the patient to the doctor’s office and they hear the doctor telling them it’s in their head, families become less supportive of their loved ones and go, well, doctor said, this is in your head. I don’t know why you feel so awful. And so families need the same point of view of trust your loved one’s perceptions. There’s no reason not to. Malaboring hypochondria is extremely rare. Gets talked about a lot. I’ve been practicing for over 50 years. I have rarely seen, seen anybody with those truly with those symptoms. So trust yourself. Good. Dr. Deb Muth 44:03I love that. What do you wish every clinician understood about listening? Neil Nathan MD 44:13I wish that every clinician had the same curiosity that we do, which is, I might not understand why this being in front of me has these symptoms or is ill, but I’m going to do everything in my power to figure it out. That means I’ll learn what I need to learn. I’ll study what I need to study to figure out why this person is sick. I really wish, and I understand kind of why that’s happened. My wife always thought that everyone was like me, which was Saturday mornings. My great joy in life was getting up early with a cup of coffee and reading medical journals or obscure medical books. That was my joy. She was shocked that most other people don’t. The way medicine actually evolved. We’re burning out doctors at a rate never before in the history of this planet by making them do things that are not in the service of patients, but are in the service of making money. And so doctors are being given seven minutes per visit. If you have a complicated person, there’s no way you could do income. Seven minutes. The way the system is set up, it doesn’t allow doctors to do their job. And then they’re under tremendous pressure to get the charts filled out properly, the way the advent of electronic medical records supposed to be. This great thing is it’s making doctors have to go home and spend two hours at home, not with their family, but getting their charts squared away. And I don’t think all patients realize the Kind of pressures that doctors are under. So to answer your question, I would like doctors to be more curious, but also, the system is broken, and I wish we could fix the system so that every patient could get the amount of time they needed with their doctor to really explore what’s going on and get to the heart of what’s happening. Dr. Deb Muth 46:31I so agree. So agree with all of that. If there was one question you would want every patient to ask their doctor, what would it be? Neil Nathan MD 46:44How would you treat me if I was your sister, mother, relative, whatever. Not what you want to do, theoretically. But if I were your wife, if I were your sister, how would you treat me? I don’t see that happening much, especially with elderly people. I see Doctors going, you’re 80. What do you expect me to do? I’m getting pretty close to being 80. And I expect you to help me because I want to function at this high level for a very long time. There was. It was an old joke that used to be Bella went in to see the doctor, and the doctor, he said, doc, my knee is all swollen and it’s tender and I’m having trouble walking on it. And the doctor said, you’re 102 years old. What do you expect? But, doctor, my other knee is perfectly fine, and it’s 102 years old also. So I once had the opportunity. I had a 100-year-old patient who had exactly that. So that was able to look at his knee and go, we’re going to take care of this. So it’s just older people need to be treated with respect, with the same thing, of absolutely no reason that they shouldn’t get the kind of attention that you would want your grandfather, your father, to have. Dr. Deb Muth 48:16Yeah, I love that question. So I have one last big question for you. If medicine were rebuilt around patients instead of systems, what would you change? First. Neil Nathan MD 48:33I would get rid of the middle man in medicine, the HMOs, the managed care organizations, where they take the profit and it’s being shunted into other areas. So rather than the physician being paid directly for what’s happening, they just get a piece of it that the managed care organization deems appropriate. You know, I grew up in what was called golden age of medicine back in the 70s, where I could do for people what they wanted done. People didn’t doubt that it was in their best interest and that if I ordered a test, it got done. I didn’t have to have someone else authorizing or tell me this is an okay or an appropriate test, I could do it. So I would go back to a. A practice of medicine, direct care, where you. Maybe there’s a system that would help reimburse you for it, but you could go to the doctor and you get what you need, and the doctor decides what you need. Actually, they’re the ones seeing you. Would a clerk in an office 600 miles away decide whether you can have this test or not? Have this test? Test? It doesn’t make any sense to me. I should be able to deliver what you want and need, and I should have the time it takes to really work with you. I’d like to go back to the 70s. Dr. Deb Muth 50:07Me too. Me too. Is there one thing that gives you hope right now for our system? Neil Nathan MD 50:16Honestly, I’m a very optimistic person. My answer is is no. I think the system is broken. I think it is being held intact by people who are profiting from this system. They have no interest in letting go of their profits for it, and they don’t have any interest in seeing that people get treated properly and well. So I think, as I said, the system’s broken. It needs to be rebuilt from the ground up. Dr. Deb Muth 50:45I agree. I agree. Dr. Nathan, thank you so much. Not just for the conversation, but for the way you’ve modeled curiosity and humility and compassion in medicine. It is an honor to work alongside of you, call you my friend, and learn from you. Thank you so much for that. For those listening, if this episode resonates with you, I want you to hear this clear clearly, your sensitivity is not a flaw. Your body is not broken. And needing a different approach does not mean you’re failing. Healing doesn’t happen by forcing the body. It happens when the body finally feels safe enough to heal. If this conversation has helped you and you feel seen, I encourage you to share it with someone who needs that as a reminder. Thank you for being here and thank you for sharing with us. Let’s talk wellness now. Neil Nathan MD 51:38So in this context, I just want people to be aware of one of my recent books, which is the Sensitive Patient’s Healing Guide, which talks about this in great detail. And the new second edition of my book, Toxic, goes over the whole mold Lyme thing in more detail. So again, that wasn’t intended to be self serving, but rather there are resources where you can learn even more about it than Deb and I are able to cover in this short interview. Dr. Deb Muth 52:09Yeah, absolutely. And your first book, Toxic, was amazing. So if people haven’t read it, you definitely want to read the second version of it because it is incredible. And Dr. Nathan, if there’s somebody that wants to get a hold of you. How do they find you? How do they learn more about what you’re doing? Neil Nathan MD 52:24A very complicated website. Neilnathanmd. Com. Dr. Deb Muth 52:30Perfect. Well, thank you for today. Neil Nathan MD 52:34You’re very welcome.The post Episode 253 – Environmental exposures, Lyme disease & multiple chemical sensitivities: integrative approaches to healing first appeared on Let's Talk Wellness Now.

Carter and Payton Bradsky—siblings, co-founders, and the CEO/CTO team behind LymeLess Health—join Dr. Karlfeldt to share a deeply personal and practical conversation about navigating Lyme+ illness and how they're using technology to change the patient experience. With Carter's lived experience battling Lyme disease, Babesia, Bartonella, and mold toxicity—and Payton's background as a former Google software engineer and product manager—this episode connects real-world patient pain points to a new kind of solution: Ella, an AI-powered companion built specifically for Lyme+ patients. Learn more (and find the app) at https://lymeless.com/.You'll hear how their family's journey began with their mother being dismissed after years of symptoms and dozens of doctors—until one chance conversation led to Lyme testing and answers. Carter and Payton break down what it was like to be kids and caregivers, how symptoms can show up differently in each person (from brain fog and anxiety to seizure-like episodes and misdiagnosis), and what actually helped them move toward remission. They also explain why Lyme care is so difficult to manage day-to-day—and how Ella helps patients track symptoms, treatments (including pulsing protocols), and lifestyle factors, then turn that data into actionable insights and shareable reports to improve doctor visits.If you've ever felt overwhelmed trying to remember what changed, what helped, or what triggered a flare—this episode offers a new framework: reduce the burden of “managing Lyme” so you can focus on living again. From weekly insights to provider-ready summaries and a future vision for research breakthroughs driven by patient data (with patient privacy and ownership at the core), this conversation is packed with hope, clarity, and next-step tools.Key Topics CoveredThe Bradsky family's “Lyme was a family affair” origin story—and how diagnosis finally happenedMedical gaslighting and dismissal: “It's all in your head” and the toll it takes on familiesBeing a child/caregiver while a parent becomes bedridden: trauma, coping, and shifting family dynamicsCarter's symptoms (brain fog, anxiety, dissociation) and the impact on athletics and college lifePayton's seizure-like episodes, epilepsy misdiagnosis, loss of license, and eventual Lyme/Babesia/Bartonella diagnosisWhy Lyme recovery is rarely linear: flare patterns, stress effects, and measuring progress when memory is impairedIntegrative treatment approaches: herbals + antibiotics, detox support, probiotics, and pulsing protocolsThe “appointment gap” problem: forgetting symptoms, underreporting, and losing clinical time to catch-upHow Ella works: daily check-ins, trend detection, symptom/treatment tracking, and weekly insightsProvider-facing reporting (“warrior report”) and the long-term goal of precision medicine + research breakthroughs via opt-in anonymized data _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email info@TheKarlfeldtCenter.comCheck out Dr. K's Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

Chronic fatigue and unexplained illness can be incredibly frustrating for patients and practitioners alike. In this episode, Dr. Ritamarie dives deep with Dr. Alison Grimston, a UK-based functional medicine physician, to uncover the hidden contributors to chronic fatigue, including mold toxicity, Lyme disease, Long COVID, and reactivated infections.You'll learn how to approach these complex cases with compassion, advanced testing, and functional strategies including lifestyle, nutraceuticals, and pharmaceutical interventions. This conversation sheds light on why many people continue to struggle despite conventional care and how a root-cause approach can restore hope and health.What's Inside This Episode?Why chronic fatigue syndromes, Long COVID, and post-infectious conditions are often misdiagnosedHow mold toxicity, viral reactivation, and vector-borne infections hide from standard testingFunctional testing strategies for Lyme, Babesia, Bartonella, and other co-infectionsThe role of genetics and nutrigenomics in guiding testing and treatmentIntegrative approaches combining lifestyle, diet, mindfulness, and targeted pharmaceuticalsEarly warning signs practitioners should never overlookWhy patience and multi-layered care are crucial for recoveryResources and Links:Download the full transcript hereDownload our FREE Guide to Supporting a Healthy and Balanced Immune SystemJoin the Next-Level Health Practitioner Facebook group here for free resources and community supportVisit INEMethod.com for advanced practitioner training and tools to elevate your clinical skillsCheck out other podcast episodes hereGuest Resources and Links:Dr. Alison Grimston's website: DrFinlays.co.uk | DoctorAllie.comFree gift

America Out Loud PULSE with Dr. Myriah Hinchey – What if your “mystery illness” is not a mystery at all? With more than half a million new Lyme cases diagnosed annually in the U.S.—and research suggesting the true number may be several million—this crisis is far larger than most realize. Lyme disease and co-infections such as Babesia, Bartonella, Ehrlichia, and Anaplasma can impact every...

America Out Loud PULSE with Dr. Myriah Hinchey – What if your “mystery illness” is not a mystery at all? With more than half a million new Lyme cases diagnosed annually in the U.S.—and research suggesting the true number may be several million—this crisis is far larger than most realize. Lyme disease and co-infections such as Babesia, Bartonella, Ehrlichia, and Anaplasma can impact every...

Understanding and Treating Complex Illnesses with Dr. Neil Nathan, author of “Toxic 2nd Edition: Heal Your Body from Mold Toxicity, Lyme Disease, Multiple Chemical Sensitivities, and Chronic Environmental Illness.” Dr. Nathan shares his expertise on the multifaceted nature of chronic illnesses, which often defy simple categorization and may be misdiagnosed as psychiatric issues. The discussion covers the impact of environmental toxins, electromagnetic fields, and infections like Lyme disease and long COVID. Dr. Nathan also highlights the importance of understanding inflammation's complex pathways and offers suggestions for both elimination of root causes and restoration of immune system functionality. The episode provides insights into new diagnostic tools and treatment methodologies for persistent and intrusive health issues.

Dr. Deb 0:01Welcome back to another episode of Let’s Talk Wellness Now, and I’m your host, Dr. Deb, and today we’re pulling back the curtain on a topic that barely gets a whisper in conventional medicine. Chronic bladder symptoms, biofilms, and the hidden genetic drivers that keep so many women stuck in a cycle of pain, urgency, and infection that never truly resolves. My guest today is someone who is not only brilliant, but battle-tested, like myself. Dr. Kristen Ryman is a physician, a mom, and the author of Life After Lyme, a book and blueprint that has helped countless people reclaim health after complex chronic illness. After healing herself from advanced Lyme, she has spent her career helping patients recover their most vibrant, resilient selves through her Inner Flow program. Her Healing Grove podcast, her membership community, and her deep dive work on bladder biofilms and stealth pathogens. And what I love about Kristen is that she teaches from lived experience. In 2022, she suffered a stroke. And not only survived it, but rebuilt her brain, resolved lateral strabismus, restored balance, and regained her ability to multitask That journey uncovered her own genetic predisposition to clotting, the very same patterns she sees in her chronic bladder patients. And that personal revelation ultimately led to her Introducing this groundbreaking work that we’re talking about today. So let’s get into it, because bladder biofilms, clotting genetics, stealth pathogens, and real recovery is the conversation women have been needing for decades. And we’ll get started. Where did this one go? There we go. Alright, so welcome back to Let’s Talk Wellness Now. I have Dr. Kristen with me, and I am so excited to talk to her for multiple reasons. A, she’s got a fabulous story, and B, she’s an expert in a topic that nobody’s talking about, and I want to learn from her, too. So, welcome to the show. Kristin Reihman 3:07Thank you! I’m so happy to be here, Dr. Deb. Dr. Deb 3:10Thank you. Well, let’s dive right in, because we have so much to talk about, and you and I could probably talk for hours. So, let’s dive into this conversation, and tell us a little bit about yourself and how you got involved in this. Kristin Reihman 3:23Well, I mean, like so many people, I think, on this path, I had, had to learn it the hard way. You know, I had to find my way into a mystery illness, a complex, mysterious set of symptoms that sort of didn’t fit the… the sort of description of what, you know, normal doctors do, and even though I was a normal doctor for many years, nothing I’d been trained in could help me when I was really debilitated from Lyme disease back in 2011, 20212, 2023. And so I kind of had to crawl my way out of that, using all the resources at my disposal, which, you know, started out with a lot of ILADS stuff, you know, a lot of the International Lyme and Associated Diseases Society, resources online, found some Lyme doctors, and then my journey really quickly evolved to sort of, like, way far afield of normal Western medicine, which is what my training is in you know, I think within a year of my diagnosis, I was, like, you know, at a Klingheart conference, and learning all sort of, you know, the naturopathic approach to Lyme, and really trying to heal my body and terrain, and heal the process that had led me to become so, so ill from, you know. A little bacteria. Dr. Deb 4:29Yeah. Yeah, same here. Like, I’ve been an ILADS practitioner for over 20 years, and when I got sick with Lyme, I was like… how did I not realize this? And I knew I had Lyme before I even was ILADS trained, but when I got really sick and got diagnosed with MS, I never thought about Lyme or mycotoxins or any of that, because I was too busy, head down, doing what I’m doing, helping people. And I, too, had to take that step back, not just physically, but more spiritually and emotionally, and say, how did my body get this sick? Like, what was I doing, and what was I not doing? That allowed this to happen, and now look at this from a healing aspect of not just the physical side, but that spiritual-emotional side as well. Kristin Reihman 5:13Totally. I have the same… I have the same realization as I was coming out of it. I was like, wow, this wasn’t just about, sort of, physically what I was doing and not doing. There was something spiritual here as well for me, and I… I feel like it really was a wake-up call for me to get on the path that I’m supposed to be on, the path that I’m on now, really, which is stepping away from the whole medicine matrix model and moving into, you know, working with really complex people. Listening to their bodies, understanding intuition, understanding energy, understanding all these different pieces that doctors just aren’t trained to look at. Dr. Deb 5:46Right? We don’t have time to learn everything, right? Like, you have time to learn the body and the medical side of things, and that’s a whole prism of itself, but then learning the spiritual energy medicine, that’s a completely different paradigm. That’s a full-time learning aspect, and it’s so different than what we learn in conventional medicine. Kristin Reihman 6:04Yeah, it’s a complete health system. Like, it’s a complete healthcare system. Dr. Deb 6:10Yes, and nobody takes it that seriously, but I, for myself, I’ve been spiritual healing for decades, and it wasn’t until I got really sick that I dived deeper into that and looked at what is it in this world that I’m owning, what belongs to generational things that were brought to me from childbirth and other generations in my family that I’m carrying their old wounds. And how do I clear some of that so that it’s not still following me? And then how do I help my kids so that they don’t have to carry what I brought forth? And it’s just… a lot of people, that may sound crazy, but that’s the kind of stuff that we need to be looking at if we want to truly heal. Kristin Reihman 6:54Yeah, and I think it’s also, it’s inspiring, you know, because when people… and I would tell this to my patients with Lyme and these sort of mystery illnesses, like, look, you are on this path for a reason, and this is going to teach you so much that you didn’t necessarily want to learn, but you need to learn. And this… nothing that you learn or change about your lifestyle or the way in which you move through the world is gonna make you a worse person. Like, it’s only gonna sort of up-level you. You know, it’s gonna up-level your diet, and your sleep habits, and your relationships, and your toxic thinking, like, it’s all gonna change for you to get better, and that’s… that’s a gift, really. Dr. Deb 7:27It really is, and I tell people the same thing. Like, we can look at this as… something that’s happening to us, or we can look at this as something that’s happening for us. And that’s how I looked at my MS diagnosis. This was happening for me, not to me. I wasn’t going to be the victim. And you have a very similar story, so tell us a little bit about your story and what kind of catapulted you into this in 2022. Kristin Reihman 7:52Well, by 2022, I was, like, 10 years out of my Lyme hole, and I had been seeing patients, you know, I had opened my own practice, and I was working for another company, seeing, families who have brain-injured children. I was their medical director, still am, actually. And so I was doing a patchwork of things, all of which really fed my soul. You know, all of which felt like this is, like, me, aligned with my purpose on the planet. And so, based on a lot of my thinking, I sort of figured, okay, well, I’m good now, right? Like, I’m on my path now, like, the universe is not going to send another 2×4. And then the universe sent another 2×4. And in 2022, I had an elective neck surgery. You kind of still see the little scar here for my two-level ACDF. Because I had crazy off-the-hook arm pain for, like, a year and a half that I just finally became, like, almost like it felt like I was developing fasciculations and fiery, fiery pain, and I just got the surgery, and the pain went away. But when I woke up, I was different. I didn’t have a voice. Which is a common side effect, actually, of that surgery that resolves after a few months, and in many cases, and mine did. But I also didn’t have, normal balance anymore, and my right eye turned out a little bit, and I couldn’t multitask. And my job is all about multitasking. As you know, with very complex people in front of you, you’re hearing all these pieces of their story, and you’re kind of categorizing it, and thinking about where they fit, and you’re making a plan for what to work up, and you’re making a plan for what to wait until next time. It’s like all these pieces, right? You’re in the matrix. And I… I couldn’t hold those pieces anymore. And I didn’t realize that until I went back to work a couple months after my, surgery, because my voice came back and was like, okay, well, now I’m going back to work. And then I realized, I can’t do simple math. In fact, I can’t remember what this person just said to me, unless I read my note, and I can’t remember taking that note. What is going on? And so I had a full workup, and indeed, I had some neurological deficits that didn’t show up on an MRI, so they must have been quite tiny. Possibly were even low-flow, you know, episodes during my surgery when my blood pressure drops really low with the medicines that you’re on for surgery. But I, basically had, like, a few mini strokes, and needed to recover from that. So that was sort of the… that was the 2×4 in 2022. Dr. Deb 10:09Wow. So, what are, what are some of the things that you learned during that process of that mini-stroke? Kristin Reihman 10:17Well, the first thing I learned is that, something that I already knew from working with the Family Hope Center, which is that organization I mentioned that helps families heal their kids’ brains, I know that motivation lives in the ponds, and if you have a ding or a hit to the ponds, like, you don’t want to get out of bed in the morning, you don’t want to do the work it takes to heal your brain, in my case. And I remember spending several months in the fall of 2022 just sort of walking around my yard. With my puppies, being like, This is enough. I don’t really need to work anymore, right? Like, I don’t… why do I need my brain back? Like, I don’t need to have my brain back to enjoy life. You know, I’ll have a garden, I have people I love and who love me, like, why do I need to work? Like, my whole, like, passion, purpose-driven mentality and motivation to kind of do and be all the things I always strive to do and be in the world, was, like, gone. It was really interesting, slash very alarming to those who knew me, but being inside the brain that wasn’t really working, it wasn’t alarming to me. I was just sort of like, oh, ho-hum, this is my new me.Well, luckily I have some people around me, I like to call them my healing team, who sort of held up a mirror, and they’re like, this is not you, and we’re gonna take you to a functional neurologist now. And so, I ended up seeing a functional neurologist who, you know, within… within, like probably 6 visits. I had all these, like, stacked visits with him. Within 6 visits, my brain just turned on. I was like, oh! Right! I need my brain back! I gotta fix this eyesight, I gotta get my balance back, and I gotta learn how to do simple math again and multitask. So, after that sort of jumpstart, I actually did the program that I, you know, know very well inside and out from the Family Hope Center, where I’d been medical director for 10 years. And, it’s a hard program, it’s not… not for wimps, and it’s certainly… I wasn’t about to do it when I had no motivation, so I’m really grateful to the functional neurologist who helped me kind of, like get my brain… get my pawns back, and my motivation back, my mojo. And then I’m really grateful to the Family Hope Center, because if I didn’t have that set of tools in my back pocket, I would still have an eye that turns out to the side, I would still have a positive Romberg, you know, closing my eyes, falling over backwards, and I would still have, a lot of trouble seeing patients, and probably wouldn’t be working anymore. Dr. Deb 12:32I can totally relate to that. When I got my MS diagnosis, you know, there’s a period of time where you go, okay reality kicks in, and I’m thinking, okay, how long am I going to be able to work? How long am I going to be able to play with my kids and my grandkids and be able to be me? And I started looking at, how do I sell my practice, just in case I need to do this? How do I step back? And I spent probably about 9 or 10 months in that place of, this is gonna be my life, and it’s not gonna be what I’m used to, and, you know, how are we gonna redesign my house, and do this, and that, and… Finally, my husband looked at me one day, and he’s like, what the hell is wrong with you? And I was like, what are you talking about? He’s like, this is ridiculous. He’s like, you fix everybody else. He’s like you can fix yourself. Why do you think you can’t fix yourself, or you don’t know the people that can fix you? You need to get out of this, and pick yourself up, and start doing what you tell your patients. And… and I sat there, and at first I was like just did he know that I’m sick? Like, I have MS. I took that victim mode for a little bit, and then I went, no, he’s right. Like, this is my wake-up call to say, I can reverse this, I can fix this, and total, total turnaround, too. Like, I started reaching out to my friends and colleagues, because I kept myself in this huge bubble, like, I didn’t want anyone to know what was going on with me, because I was afraid my patients wouldn’t see me, what are my staff going to say? My staff are going to leave, and if I lose my business, what am I going to do? And da-da-da-da, all those fears. And then… when I finally started opening up and sharing with people, people started bringing me other people, and you need to talk to this person, you need to talk to this person. They connected me here and there, and this place, and 18 months later, I was totally back to normal again. And now my practice is growing, and we’re adding on, and it’s bigger, and I’m taking on more projects than I feel like myself, and… and I was a lot like you, too. Like, I couldn’t remember my protocols that I’ve done for 20 years. I had to depend on what was in the EHR to pull forward, because I always had them in my notes, so I didn’t have to type them all the time, but I was like I have to pull that forward, because I don’t remember the name of the supplement that I’ve used for 15 years. I don’t remember what laps I’m ordering. I don’t remember the normal values of this stuff. And now it’s back on the tip of my tongue, but at the time, it was a little scary, for sure. Kristin Reihman 14:47Wow, so scary. Well, that’s a remarkable story, and why I can’t wait to have you on my podcast, but I’m really… I’m really happy that you had a healing team around you, too, who was like, yeah, nope, that’s not your… that’s not the train we’re on. Get off that train. Come back on your usual train. What are you doing over there? Dr. Deb 15:03Yeah, and you know, I hope that a lot of patients have that, or people that are experiencing this have that, but there’s so many people who don’t have that. And they need somebody, they need somebody in their corner, like we had in our corners, to help pick them up and say, this doesn’t have to be your reality. It can change, but it is a lot of work, like you said. It’s a lot of work. It’s not… Kristin Reihman 15:25Yeah, no, it’s a lot of work. So when I started off. I was work… I was doing probably 4 hours a morning, like, 4… basically, my entire morning was devoted to brain training and healing my brain through the ref… you know, we… I mean, I can get into the details of it, but basically it’s a lot of, like, crawling on the floor. On your belly, creeping on your hands and knees, doing reflex bags to stimulate, you know, more blood flow to the brain, doing a lot of smells. You know, and just staying with it, you know? And I remember balking, even in the beginning, I was, like, seeing some changes, I was feeling more motivated. I remember feeling this… I started noticing it was changing about 2 weeks in, when I would get up in the morning. And I would… I noticed I would start… I would do my, like, beginnings of the day, I would get the kids on the bus, I would do everyone’s breakfast, I’d do the dishes, and I’d be, like, sitting down and being like, hmm, like, what am I supposed to be doing now? Like, where… What is my purpose today? And because I had this plan, I was just like, well, I know that has to happen, so I may as well do that now. And I would get on the floor, and I would start crawling down the length of our hallway. And within about 8 laps, I would feel my brain, like. I felt like it integrating. I would feel things, like, just coming online, and I’d be like, oh, right. I know who I am, I know what I’m doing today, I have these other things this afternoon, I gotta get this done before noon, and I would do it. But it was really interesting, and I’ve never been a coffee drinker, but when I thought of what that felt like, to me, that’s how people often describe, like, my brain doesn’t wake up until I have coffee. I never needed coffee to have… my brain woke up before I’d wake up, and I’d be like, bing, and I’m ready to go. But when I had the brain injury for those 9 months, it wasn’t that way the whole time. In the beginning, it was very hard to get my brain back in the morning, and it was creeping and crawling that would pull it in. Dr. Deb 17:08Wow. Is there one particular thing that you did that you felt made the biggest difference to rebuilding your brain? Kristin Reihman 17:15Crawling on my belly like a commando, wearing elbow pads, knee pads, actually two sets of knee pads, wearing toe shoes, and just ripping laps on my floor. Dr. Deb 17:26Oh, and that’s so simple to do. So why does that work? Kristin Reihman 17:31So interesting, and I… this is the kind of… this is the… the story of this is something that I think is bigger than all of us, and I wish everybody knew how to optimize your brain using just the simple hallway in your house. But essentially, if you take a newborn baby. And you put them on mom’s belly, and they’re neurologically intact, and maybe you’ve seen videos of this. There used to be a video circulating about a baby born onto mom’s belly, nobody touches the baby, and in about 2 minutes and 34 seconds, that baby crawls on its belly, like, uses arms, uses its toe dig with its little babinsky, and pushes its way up to mom’s breast. Latches on with its reflexes, and there you go. That baby keeps itself alive through its primitive reflexes. So it’s essentially telling its brain, every time it runs those reflexes, every time it does a little toe dig, every time it, like, swings its arm across in a cross-later, hetero… what do we call, a homolateral pattern. That little baby is getting a message to its brain that says, grow and heal and organize. And because all the reflexes come out of the middle and lower brain stem. That’s the part of the brain that’s organizing as a baby. And as a baby grows and does the various things a baby does using its reflexes, like eventually on its belly, crawling across the floor, and then popping up to hands and knees, and creeping across the floor, and eventually standing and walking, all of those things are invoking a different set of reflexes that tell the brain to grow and heal and organize. So it’s almost like the function creates the structure, and if you run those pathways again and again and again your brain will get the message to basically invoke its own neuroplasticity, and that’s how a baby’s brain grows. And it turns out, any brain of any age, if you put it through those same pathways, it will send a message of neuroplasticity to the brain, and the brain will grow and heal and organize. Dr. Deb 19:16That was going to be my question, is why aren’t we using this for elderly people with dementia, or Alzheimer’s, or stroke, or Parkinson’s, or things like that, to help them regrow their brain? Kristin Reihman 19:28Well, because number one, nobody knows about it. Number two, even when people do know about it, nobody likes to be on the floor like a baby, creepy and crawling. And least of all the stubborn old people with dementia who are, like, who don’t even think they have a problem. I mean, the problem with the brain not working, as I discovered, and it sounds like you discovered, too, is the brain that’s not working doesn’t know it’s not working, or worse, doesn’t care. You know, and so it’s tricky with adults. With kids who, you know, you have some sort of power over, you can often make your kids do things that they don’t want to do, like eat their vegetables, or creep and crawl on the floor for 80, you know, 80 laps before they get to go, you know, do their thing. But adults are a little trickier. Dr. Deb 20:10Is there another way for us to be able to do that same thing without the crawling on the floor? Like, could they do it in a sitting motion, or do they need that whole connection to happen? Kristin Reihman 20:21Well, they need to be moving in a cross pattern, and they need to be moving their arms and their legs in such a way that stimulates the reflexes. But you can do that on your bed, you can do it face down on your bed by getting into a pattern, and switching sides and, you know, moving your legs and your arms in the opposite… in the, you know, an opposite cross pattern, and that will get you some of the benefit. And we, in fact, we have… we work with kids who are paralyzed and who don’t… aren’t able to independently move forward in a crawling pattern, who have people coordinating their movements so that they get the same movement, and the brain registers it, and they do make progress, and some of them eventually. Crawl, and then creep, and then walk. Dr. Deb 20:59Wow, that’s so… and it’s so simple and easy for people to do. Kristin Reihman 21:04Well, it’s simple. I don’t know that it’s easy. I do… I do… having done it myself, I will say it’s probably the hardest thing I’ve ever done, was literally crawl my way out of that brain injury. And I’m so glad that I knew what to do, and I’m so glad I had people push me to remind me that it was important, because… I’ll even… I’ll share another story of my own resistance. So, about 2 or 3 weeks into it, I was up to 300 meters of crawling on my belly. And 600 meters of creeping on hands and knees, which was really killing my knees, which was why I was wearing two knee pads. And, I started to get this feeling that maybe I wasn’t doing enough. Like, even though I was noticing changes, and even though I was feeling more purpose, and I was getting organized in the morning, I could tell it was making a difference. I… I knew, I remembered that usually the kids on our program are doing a lot more than that, including my own… my youngest kids, but I made them creep and crawl, even though they didn’t have serious brain injuries, I just thought, we’re gonna optimize everyone, get on the floor, get on the floor. Lord so I was… I was nervous about not doing enough, so I… I reached out to the member… one of the members of the team, and I said, you know, hey, Maria, what’s… what do you think about my numbers? And here’s a… here’s a video of me creeping and crawling, what do you think? Am I doing it right? And she said, you’re doing it right, but how many, how many meters are you doing? And I said, I’m doing 300 meters of crawling on my belly, and 600 meters of creeping, and she’s like, oh. Yeah, that’s not nearly enough for an adult. She’s like, Matthew probably gave you those numbers because he felt bad for you and thought you were going to be still working. He didn’t know you were going to take off from patients. Now that you’re… since you’re not working, you need to do more. I was like, okay, tell me… tell me how much I’m supposed to do. And she goes, you need 900 meters of crawling on your belly, and 3,600 meters, 3.6 kilometers of basically crawling on my hands and knees. Dr. Deb 22:51Oh my gosh. Kristin Reihman 22:52And I just shut down. Dr. Deb 22:54Yeah. Kristin Reihman 22:55I was like, okay, screw it. I’m not doing it. Dr. Deb 22:58And I spent a day or two just not doing it and feeling petulant, and then I was like, you know what? Kristin Reihman 23:01Forget that, I was noticing some benefit. I’m gonna do my 300-600. So, the next day, I went and did 300 and 600 while my daughter was at physical therapy, and we got back in the car, and I said, hey, I’m so excited, I finished my… all my creepy and crawling, and it’s only 10 a.m. on a Saturday, I’m done for the weekend. And she did this. She’s sitting in the car, she looks at me, she goes. Was that your whole program, or was that a third of your program? Dr. Deb 23:28How old is she? Kristin Reihman 23:01Well, she’s, like, 20 now, but she was 18 at the time, and she… she had my number, and I was like, Tula! How can you say that? I’m working so hard! And she’s like, Mom? You need to stop seeing patients completely, and do what they tell you at the Family Hope Center. Because we’re your family, and this is your brain we’re talking about, and we need you to have all your brain back. And I must have looked terrible, because she goes, too much? Dr. Deb 23:54You raised a good daughter. Kristin Reihman 23:58And I was like, well, let me tell… let me ask you, do you mean that? She goes, yeah, I really mean that. I’m like, then it’s not too much. I needed to hear that. Thank you. And I went home, and I finished another 600 of crawls. I didn’t… I never got up to 3,600 of creeps. It was just too much for my knees. I got to 900 and 900, but that was the end of my resistance, and I just did it. Dr. Deb 24:17I just did it. Yeah, your family needed you, right? I mean, when somebody in your family that you love tells you they need you, that’s a huge motivating factor. Kristin Reihman 24:27Yeah, yeah, I’m so grateful for that. So, I did that for 9 months, and at the end of 9 months, my eye was straight and stayed straight, my balance was back, I was multitasking again, and I could take, you know, days and days off of creeping and crawling and not notice a dip. I was like, I’m done. Dr. Deb 24:45Wow, that’s awesome. Kristin Reihman 24:46Yeah. Dr. Deb 24:47During this process, you also discovered that you’re part of 20% of the people with clotting genetics. Tell us a little bit about that. What’s your understanding in that? Kristin Reihman 24:58Well, so, I’ll back up. So, before I had my stroke, I had already been seeing patients with really complex, you know, patients like yours, really complex stories, lots of different things going on, kind of the perfect storm for if they got a tick bite, they tanked. Dr. Deb 25:12and… Kristin Reihman 25:13And I’m one of those people, and my patients were those people. And about 7 years ago, I had one of these patients who said to me, you know, I’ve never told you this, but when I was in my 20s, I had so many bladder infections, so much, like, you know, kind of interstitial cystitis, they said it was, and they said it wasn’t an infection, but it felt like one. And I’ve been doing a little research, and I’ve learned about this woman whose name’s Ruth Kriz, she’s a nurse practitioner, and she sees Patients, and she has… she works with practitioners, and she basically heals interstitial cystitis. And I want you to work with her, I want you to learn from her. And I was like, I’m game. That sounds really interesting, I have no idea what she’s doing, and you don’t usually hear the words cure and interstitial cystitis in the same sentence, so, like, I’m in. So I reached out to Ruth, and long story short, I’ve been working with her for the last 5 or 7 years basically increasing the number of patients who I’m diagnosing now with these hidden bladder infections that are really often what’s at the root of these interstitial cystitis symptoms, meaning, you know, you go to the doctor, you pee in a cup, they look for something, they say there’s no infection here, so, you know, you’re probably crazy, or, you know, you probably have just a pain syndrome, we can’t help you. And actually, if you look with a much more sensitive test, and if you break down the biofilms where these bugs kind of are living in the bladder, you find them. And then you can treat them, and then people get well. So I knew about this, and I, didn’t have any bladder infections that I knew about, and what I did start to think about after my stroke was, well, maybe, since these people who have these bladder infections often have issues breaking down biofilms, the same genetics that lead you to have trouble breaking down biofilms, which are these places where the bugs are kind of hiding in your body, have trouble breaking down clots. And I just had some strokes. I wonder if I have maybe some of these clotting genetics that I’m looking for in all my bladder people. And so I looked, and surprise, surprise, I had not one, not two, but, like, six of them. Ruth said to me, Ruth said, Darlin, I don’t know how you’re standing up. This is more than I’ve ever seen in any of my patients. And she’s been doing this for, like, 4 years now. I was like, oh boy, that’s not good. But in retrospect, it made a lot of sense to me, because having the clotting genetics I have. puts me at risk for severe, you know, chronic Lyme that’s intractable, which I had. It puts me at risk for trouble with, you know, having surgery and clotting and, you know, low blood pressure and low flow states. It puts me at risk for the cold hands and cold feet that I had my entire life until I started treating the clotting issues by taking an enzyme that breaks down little microclots. I mean, I was the person in med school who’d put my hands on people, be like, I’m so sorry. My hands are ice. Warm heart, cold hands, warm heart. Yeah, not anymore, because I’ve treated it. But yeah, so I was surprised slash not surprised to find that I’m one of the people in my community who is a setup for chronic infections and, strokes and bladder infections. Dr. Deb 28:22So you just had that predisposition that took you down that path. Kristin Reihman 28:28Yeah, I think so. Dr. Deb 28:30What are some of the layers of biofilm and the stealth pathogens, like tick-borne diseases and things like that, hiding inside us that… what are some of the symptoms look like, and how do they look different in people with clotting disorders versus the common tick-borne disease? Kristin Reihman 28:47I would say they’re very similar, so it tends to be poor peripheral circulation, so if you put your hands on your neck, and your hands feel cold to your neck difference in the heat, right? The amount of blood flow in your sort of axial skeleton and area as compared to the periphery. And that can indicate a biofilm kind of predisposition or a clotting disposition. It doesn’t necessarily mean it’s there, but it’s a clue, right? Another clue is a family history of any kind of clotting disorders. So, miscarriages, heart attacks, especially early heart attacks, strokes, especially strokes in young people. These things are… are clues that we should probably look for some kind of clotting issue. And of course, in my population, I’m always thinking about it now, because if you have not been able to get well with the usual things for Lyme disease, for example, or Babesia or Bartonella, all of which, by the way, can form biofilms or, you know, love to live and hide in biofilms, then chances are your body’s having a hard time addressing those biofilms. And it turns out, so the connection between the clotting and the biofilm piece is that the same proteins that our body uses to break down Biofilms are used to break down microclots, blood clots, and soluble fibrin, which are the sort of precursors to those clots. And so, if we have an issue kind of grinding up those just normal flotsam and jetsam in our blood flow, then our blood flow is going to become sticky, and our blood will become sort of stagnant and sludgy, and that’s sort of a setup for not being able to heal from infections. Dr. Deb 30:25Is one of the genetic markers you look at MTHFR? Kristin Reihman 30:28I look at that, but I don’t consider that a clotting issue, unless it leads to high homocysteine. So, homocysteine can be either high or low, they’re both problematic. And MTHFR can create either an over-methylation situation, and sometimes if people have low homocysteine, it’s almost worse, because they’re such poor detoxers that they can’t actually get anything out of their system, and they get sludgy for that reason. But I think in terms of the clotting, the bigger issue is high homocysteine, which, you know, typically the MTHFRs, the 1298 would be more implicated for that. Dr. Deb 31:02Yeah, it kind of sets you up. Dr. Deb 31:04Yeah, yeah. Kristin Reihman 31:05I’m curious what you’re seeing. I know since the pandemic, we see a lot of people with elevated D-dimer levels.Are you seeing some of that in your practice, too? Like, we’re seeing more of it, and now that you’re talking about this, I’m wondering if some of those people are predisposed to some of these genetic makeups, and that’s why we’re seeing such a high rise in that.It… and this is connected, and it’s a piece we’re missing. Kristin Reihman31:29Yes, I do think it’s a piece we’re missing. There was a very interesting study that came out of South Africa. A physician in his office did a clinical study on his patients using 3 blood thinners. So he put people on Plavix, and Eliquis, and aspirin, all at once. It… yeah, you’d be hard-pressed to find a doctor in the States to, like, you know, kind of risk that, because most people don’t even want people on aspirin and Flavix at the same time. Dr. Deb 31:55But Kristin Reihman 31:56They put them on 3 different blood thinners, people with long COVID, and in 6 months, 80% of those people were completely free of symptoms. Dr. Deb 32:04Wow. Kristin Reihman 32:05Yeah, yeah. Now, my question is, what about that 20%? Like, what’s going on with them? And I suspect, they weren’t looking at the other half of the pathway, because when you give a blood thinner, you’re not doing anything to help the body break down clot. You’re simply stopping the body from making more of it. And you rely on the body’s own mechanisms, you know, plasminogen activating inhibitor, for example to kind of grind up those clots and take them out. But when people have a mutation, say, in that protein, they’re not going to be able to grind up the clots, and so my suspicion is the 20% of people who didn’t get well in that study were people who had issues on the other side of the pathway. Dr. Deb 32:44Yeah, they weren’t able to excrete that out and maybe have some fiber and issues and things like that, and that wasn’t being addressed. Kristin Reihman 32:50Yeah Dr. Deb 32:51Yeah Kristin Reihman 32:52Of course, COVID makes its own biofilm. There’s a whole… there’s a whole new, you know, arm of research looking at sort of the different proteins that get folded in the body when COVID spike proteins are in there, kind of creating these almost, like, little amyloid plaque situations in your blood vessels. So, I do think that people who can’t break those down are really at risk for both COVID and the shots. You know, the spike protein comes at you for both of those, right? Dr. Deb 33:17Yeah. Did you use any lumbrokinase or natokinase in your situation? Kristin Reihman 33:22So lumbar kinase is what I use. It’s my main player. I use the Canada RNA one, which is, you know, I think, you know, more studied than any of the other ones, and because of its formulation, it’s about 12 times more potent than anything else out there. So that’s what I’m pretty much on for life. You know, that’s… I consider that kind of my…My… my main game. Dr. Deb 33:44Yeah, I agree, I love Limerocheinase for that, that’s really good. So you recently hosted a retreat around this topic. What were some of your biggest aha moments for the participants as they started unraveling some of these biofilm layers? Kristin Reihman 34:00Yeah, no, it was so fun. My sister and I host retreats together. She came out from California and did the yoga, and I did the teaching about biofilms and bladder issues, and it was really fabulous, because a lot of these folks are people already in my community. A few of them were new, and so we had this wonderful Kind of connection, and learning together, and just validation of what it is to live with symptoms that are super inconvenient, you know? Like, one of the… one of the members even, or participants even brought a big bag of, like, pads, and she’s like, listen, ladies. This is what I’m going to use to get through the week. If you want to borrow, I’ll put my little stash over there, and I think they all went by the end of the week. So we… my aha moment was just how powerful it is to be, hosting community and facilitating conversations where people really feel seen and heard, and just how important that is, especially post-COVID, right? When we, you know, so many people just really missed that piece of other humans. And, yeah, I love… I love being able to help people connect around stuff like that. Dr. Deb 35:00That’s awesome. So, for people who are listening that have that mystery, quote-unquote bladder issue, frequent UTIs, interstitial cystitis symptoms, or pelvic pain, or bladder spasms. Where should they start, and what are the first clues that tell you this is biofilm-driven? Kristin Reihman 35:20So, I think it’s always a good idea to… to do a test, you know, to take a microgen test. There’s a couple companies out there, I think Microgen’s the one that I rely on more than any of the others, and it requires, you know, not only doing a very sensitive test like Microgen, but breaking down biofilm before you take it. So, I always encourage people to take a biofilm breaker like lumbrokinase for 5 days leading up to the test, so you’re really grinding into the bladder wall and opening up those biofilms so that when you catch whatever comes out of your bladder, there’s something in there. If you don’t have bladder biofilm, nothing will come out, and you’ll have a negative test, and that’s usually confirmatory. If you’ve done a good provoking with BLUC or, you know, lumbrokinase for 5 days, and nothing comes out then I usually say mischief managed. That’s… that’s a great… that’s great news for you, right? And most people in my community, when they look, they find something, because, you know, not for nothing, but you’re in my community for a reason, right? Dr. Deb 36:17And so… Kristin Reihman 36:18So, yeah, and typically then we need to get into the ring with those bladder biofilms, and it doesn’t… it doesn’t usually take one or two tests, it’s many tests, because the layers are deep. I’m working with children, too, and even in small kids, they… if they have the right genetics, and if they’re living in an environment that is… that kind of can also push them to make more biofilms, like living in mold, for example, is a huge instigator of inflammation and biofilms, and also, you know, microclots and fibrin in the body. then those layers can go deep. And so, we’re peeling the layers one at a time, and we’re treating what comes out, and supporting people along the way. Dr. Deb 36:57With these microgen tests, can you find biofilms in other parts of the body as well, or is it primarily bladder? Kristin Reihman 37:03No, you can find… you can culture… and you can send a microgen PCR for any… any, you know, secretion you want. So they have a semen test, they have a vaginal test, they have a nasal test, you can send sputum, you can culture out what… you can stick a swab in your ear. There’s all sorts of… anything that you can put a swab in, you can… you can send in there. Oh, that’s awesome, that’s amazing. Yeah. Dr. Deb 37:26So, once you identify the drivers, genetics, environment, stealth infections, what does an effective treatment or reversal process look like for people? Kristin Reihman 37:36For the… for the bladder in particular? Well, I wish I could say it was herbs or oxidation, which are my favorite things for Lyme. I haven’t found those to work for the bladder, and so I’m using antibiotics. Which, even though I’m a Western-trained MD, it was not my bag of tricks. You know, when I left, sort of, the matrix medicine model, I really stopped using those things as much as possible, and I’ve had to come back to them, because they really, really work, and they’re really, really needed. So I love it if someone else out there is getting results with something other than antibiotics, please contact me and let me know, because I have plenty of patients who are like, really? Another antibiotic? I’m like, I know. But they work. We also do a really careful job, you know, I work with Ruth Kriz on every case, and we do a very careful job in finding the drug that’s going to be the least broad spectrum, and that’s really only going to tackle the highest percentage bug there. So, MicroGen does this really cool thing. It’s a PCR, next-gen sequencing, they’re looking at genetics, so you don’t have to have it on ice, it can sit on your countertop for a month, and you can still send it in. And they, they, they categorize by percentage, like, what’s there. And they’re not just looking for the 26 or 28 different bacteria that you would get if you were looking at a culture in your doctor’s office. They’re looking for 57,000 different organisms. Fungal and bacterial, yeah? And so, this is why I say, if there’s something there, and you’ve broken down the biofilm, microgen will find it. Dr. Deb 39:06That’s really great. That was going to be my question, is does it pick up fungal biofilms as well? So I’m so glad you mentioned that, because a lot of times with bladder stuff, it’s fungal in that bladder, too, and then we’re throwing an antibiotic at it and just making it worse if it’s fungal in there. Kristin Reihman 39:21Yeah, yeah, that’s… they… and I recently saw one, I had a little Amish girl who came back with 5 different fungal organisms in her bladder. And a whole flurry, a slurry of bacteria, too. Yeah, pretty sick. And that’s usually an indication that you’re living in mold, honestly. Dr. Deb 39:37Now, conventional medicine treats the bladder as a sterile organ, and rarely looks at biofilms. Why do we believe that this has been overlooked for so long, and what are they missing? Kristin Reihman 39:53Dr. Dr. Deb 39:53I’m loaded up. Kristin Reihman 39:54One of the many mysteries of medicine. I have no idea why people are like, la la la, biofilms. I mean, we know, so when I say we know, so when I trained, you know, I trained at Stanford for my medical school, I trained at Lehigh Valley for residency. Great programs, and I learned that, oh yes, biofilms, they exist in catheters of bladders. When people have an indwelling catheter for more than a month and they spike a fever, it’s a biofilm, but it’s only in the catheter. Really? Why does it stop at the catheter? Dr. Deb 40:23Yeah. Kristin Reihman 40:25Or, you know, now chronic sinusitis, people are recognizing this is a bladder… this is not a bladder, this is a biofilm infection in your sinuses. But we’re really reluctant to kind of admit that there’s, you know, that we’re teeming with microorganisms, that they might be setting up shop, and for good, right? Like, it’d be great if they were in biofilms as opposed to our bloodstream. Like, we don’t want them in our bloodstream, so thankfully they wall themselves off. But yeah, I think they’re everywhere. I mean, they found a microbiome in the brain, in the breast, in the, you know, the lung. There’s microbiome, there’s bugs everywhere. And the question is, are they friend or foe? And the bladder really shouldn’t have anybody in it. Because, think about it, you’re flushing it out, you know, 6 times a day. You know, most people who can break down biofilm because their clotting genetics are normal, and because they’re peeing adequately, will never set up an organism shop in their bladder. Even though things are always crawling up, we’re always peeing them out. Dr. Deb 41:23Yeah. Kristin Reihman 41:23And then there’s the 20% of us who… Who aren’t that way. Dr. Deb 41:30Oh, so you run the Interflow program and a number of healing communities. What tools and teachings have been the most transformational for people going through this journey? And tell us a little bit about the Interflow program, too, please. Kristin Reihman 41:44Okay, maybe I’ll start there, because honestly, I have to think about the which tools are most transformational. The Interflow program is my newest offering, and we developed it because my team and I were looking around at the patients we had, and so many folks were needing to go down this… we call it the microgen journey, like, get on the microgen train and just start that process. And there was just a lot of hand-holding and support, and… education that they were requiring. And by the way, their brains aren’t working that great, because when you have these infections, you know, you’re dealing with, like, downloads of ammonia from time to time from the bladder organisms, you’re dealing with a lot of brain fog, overwhelm, you know, there’s just a lot of… you know how our patients are, they… they… they’re struggling, and they really need a lot of hand-holding, and so we were providing that. But we kept thinking, like, gosh, it would be great to get these guys in community, like you know, we can say all we want, like, you know, it’s important to check your pH, it’s important to, like, stay on top of the whatever, but it’d be great to have them hear that from one another, and to have them also hear, sort of, that they’re not alone. So, because we had some experience running communities online, which we started during the pandemic and has been super successful, we said, let’s do this, let’s create a little online community of our inner… of our, you know, call them… informally, we call them our bladder babes. But, like, let’s create a community of people who are looking to really heal and get to this deep, deep root that no one else is doing. And that was really the key for me, that nobody else is really doing this. Very few people are doing it or aware of it. I wish that weren’t the case, but as it stands now, it’s pretty hard to find someone to take this seriously. Most doctors, if you even take a microgen to them, they’ll say, oh, there’s 10 organisms on here, that’s a contamination. That must be contaminated. Well, yeah, buy your biofilms, but they don’t know about biofilms, so they think it just comes from the lab. Dr. Deb 43:31Something. Kristin Reihman 43:32I don’t know. But, yeah, basically it was because I felt called to do this service that no one else is providing, and I wanted to do it in a way that was going to be really optimally supportive for people. So we created a membership, basically. Dr. Deb 43:44Do you see a difference in men and women? Obviously, women have this problem more than men, but do you see a difference in how many men that have these self-infections or live in mold compared to women? Kristin Reihman 43:57I… it’s hard to know, really, what the, sort of, prevalence is out there, I will say, in terms of who calls our office. Dr. Deb 43:03It’s, you know, 95% women call our office. Kristin Reihman 44:08And occasionally, we’ve had someone call our office on behalf of a husband or a son. I just saw a woman whose 2-year-old son is in our Bladder Babes community. But typically, it’s the women who are seeking care around this, and I don’t know if that’s a function of their having more of the issues. I suspect it is, because as you said before, so many more women deal with these complex mystery illnesses than men.But there certainly are men who have them. Dr. Deb 44:33Yeah. So, you’ve lived through Lyme, chronic illness, stroke, and now biofilm-driven bladder issues, and you’ve come out stronger. What mind shifts helped you stay resilient through all of these chapters? Kristin Reihman 44:50I think there have been many. I think the first one I had to really, Really accept and lean into and kind of internalize. Was this idea that, I… I couldn’t… I didn’t have to do the work that I was doing. Dr. Deb 45:09You know? Kristin Reihman 45:09In order to be of value to the world. You know, I’d trained in a certain way, I had, you know, I had this beautiful practice. I was working in the inner city, I was working with my best friend, we were seeing really needy people who had no money, and it felt really, like, you know, I felt very sort of service-driven and connected to a purpose. And I think the hardest thing in the beginning for me was realizing, I can’t do that work anymore. That’s not the work that I’m… needing to do, and to make a leap into the unknown. It felt like, you know, having a baby at 45 and not doing any ultrasounds, or any tests, and just being like, I’m birthing something here. I don’t know what it is, it’s me, but who knows what she’s gonna look like, or… what this doctor is going to be, you know, what, you know, peddling in terms of her tools. That was a big leap of faith, and I think letting go of the kind of control of needing to be… needing to look a certain way and be a certain kind of doctor was a big step for me, my big initial step. Dr. Deb 46:05That’s really hard, because you’re taught and ingrained in who you’re supposed to be as a doctor, and what that person’s supposed to be, what your persona’s supposed to be. And doing a lot of the Klinghart work and some of those things, and I’m sure on the days crawling through the floor, you’re like, this is not what I was trained to do. If my colleagues could only see me now, they’d… they’d… Commit me, right? But like you said, just giving that leap of faith and saying, I’m gonna turn this over to your higher power, and you’re gonna bring me out on the other side, and trusting that, that is a vulnerability for us that is huge. Kristin Reihman 46:43Yeah, and I mean, I’d like to say it’s because I’m some sort of strong person, but truthfully, I feel like there was no other choice. Like, I had to surrender because there was… the alternative was death or something. I didn’t… I don’t know, right? There was no other choice. Dr. Deb 46:56Yeah. Kristin Reihman 46:56I couldn’t move. I was in so much pain. I couldn’t move. Couldn’t get out of bed. Dr. Deb 47:01Thank you so much for sharing all of this and being vulnerable with our audience. Where can people find you? Find your book, your podcast, your programs, if they want to go deeper with you? Kristin Reihman 47:12Yeah, thanks for asking. So, I have a website, it’s my name, kristenRymanMD.com, and all my programs are listed there. I have several, you know, I have a, sort of, a wellness… I have an online membership for well people who want to stay well and pick my brain every week around, sort of, healthy, holistic tools. It’s called The Healing Grove.I have a podcast that people can listen to for free, where I interview people like you, and you’re gonna be on it, right? She’s gonna be on it soon. Dr. Deb 47:38I’d love to. Kristin Reihman 47:39So I can share stories of hope and transformational tools with people. I also have a Life After Lyme coaching program, which is kind of the place where I invite people who are dealing with a mystery illness to come get some support, community, and guidance from someone like me, and also just from the other people in the room. There’s a lot of wisdom in those groups. And that’s… I guess that’s the answer I’ll share for what you asked earlier, like, what’s the main tool they take away? I think they take away an understanding that community really matters, and that they’re not alone. You know, I think it can be very lonely to be stuck in these… to feel stuck in these illnesses, and people need to be reminded that they’re… that they’re human, you know, and that they’re worthy of love and acceptance. I think that’s what people get from my… from my community, is kind of like, that’s the common thread. Dr. Deb 48:23They definitely need that. Kristin Reihman 48:25Man. Dr. Deb 48:26Kirsten, thank you so much for sharing your powerful story. Your work is so needed, and your ability to weave personal experience and advanced clinical insight is exactly what our community craves. And this kind of conversation helps women finally be seen and heard, which is my motto too, and gives them just the real tools to get their life back. And for everyone listening, if you’re struggling with unexplained bladder pain, frequent UTIs, pelvic discomfort, or symptoms that never match your labs, because they never quite do. You are not crazy, you are not alone. You need to find the answers, you need to be with community, and there are solutions, and conversations like this is how we bring them forward. So, thank you all for tuning in to Let’s Talk Wellness Now. I’m your host.And until next time… Kristin Reihman 49:15Thanks, Dr. Dove. Dr. Deb 49:16Thank you. This was awesome. Thank you so much. This was… Kristin Reihman 49:21You’re so welcome, you’re such a great interviewer.The post Episode 251 – Chronic Bladder Symptoms, Biofilms, and the Hidden Genetic Drivers first appeared on Let's Talk Wellness Now.

David Jernigan 0:15Hello! Dr. Deb 0:16Hi there, sorry for all the confusion. David Jernigan 0:19Oh, no worries, you gotta love it, right? Dr. Deb 0:21Oh, I can’t hear you. David Jernigan 0:23No way, let’s see, my mic must be turned off? Dr. Deb 0:27Hang on, I think it’s me. Let’s see…Okay, let’s try now. David Jernigan 0:40Okay, can you hear me? Dr. Deb 0:42Yep, I can hear you now. David Jernigan 0:43Excellent, excellent. And, how are you today? Dr. Deb 0:48I am good, thank you. How about yourself? David Jernigan 0:50I’m good. Well, it’s good to finally meet you and get this thing rolling. Dr. Deb 0:56Yes, yes, I’m so sorry about that. David Jernigan 0:58That’s alright, that’s alright.So… Dr. Deb 1:01Yeah, go ahead. David Jernigan 1:03So, tell me about yourself before we get going. Dr. Deb 1:06Yeah, so I am a nurse practitioner. I’m also a naturopath. I have a practice here in Wisconsin. I’ve been treating Lyme for about 20 years, so I’m really excited to have this conversation and learn what you’re doing, because it’s so exciting and new. David Jernigan 1:21Well, thank you. Dr. Deb 1:22Yeah, so we treat a lot of chronic illness patients, do some anti-aging regenerative things as well, so… David Jernigan 1:30Yeah, I went to your website and saw you guys are killing it, looks like. Dr. Deb 1:35Yeah. David Jernigan 1:35Got a lot of good staff, it looks like. Dr. Deb 1:37Yeah, we’ve got great staff, great patients, busy practice. We have 5 practitioners, so we have about 15,000 patients in our practice right now. David Jernigan 1:46Well, excellent. Yeah. Excellent. Yeah, yeah.So, I’m excited for this discussion. Dr. Deb 1:53Good, me too. So I pre-recorded our intro, so we can just kind of dive right in, and I’ll just ask you to kind of introduce yourself a little bit, tell us a little bit about yourself, and, and then we can just dive right into it. David Jernigan 2:08All right. I’m Dr. David Jernigan, and I own the Biologic Center for Optimum Health in… Franklin, Tennessee, and I’ve been in practice for over 30 years. I shook Willie Bergdurfer’s hand, if anybody knows who that is. It’s kind of infamous now with some of the revelations that have happened about Lyme being a bioweapon and weaponized. But, you know, I’ve been doing this, probably longer than almost anybody that’s still in the business in the natural realm. It chose me. I did not choose Lyme. Matter of fact, there were many times in my career that I was like. You know, cancer’s easier because of the fact that everybody agrees, you know, what we’re dealing with. And in the 90s, it was a whole different reality, where nobody actually understood that you could have Lyme disease and not be coming from New England.You know, so I had actually the first documented case of a Lyme disease, CDC positive.Patient that had never left the state of Kansas before. So they couldn’t say that it wasn’t in Kansas, and so she had actually been, pregnant with… twin boys, and they were born CDC-positive as well, and so it is transmitted across the placenta we know.So, I, you know, the history of how I did all this was, in the 90s, probably 1996, probably, somewhere in there, 97. With this woman, you know, I… if you go into Robin’s pathology books from back then. Which we all used, medical doctors and everybody else studying. you know, there was basically a paragraph about Lyme disease, and on the national board tests, as you recall, it was probably like, what causes, or what is, bullseye rash associated with? And you’d had to guess Lyme disease, of course. Dr. Deb 4:07Female. David Jernigan 4:08But that was, you know, considered to be more a New England illness, and you would never see it anywhere else. But here was this woman. I knew… nothing about Lyme beyond what we had gotten taught in college, which was, like I say, next to nothing. And she would not let me stop feeding me information. I mean, you gotta remember, the internet wasn’t even hardly in existence in those years. I mean, it was brand new. It was supposed to be this information highway, and So I started purchasing, like a lot of doctors do even now, they start purchasing every kind of new supplement that’s supposed to work for bacteria. There was no product in those days that actually was Lyme-specific. I mean, nobody was really dealing with it naturally. It was always a pharmaceutical situation. Dr. Deb 5:04And a very short course at that. David Jernigan 5:06Yeah, 2 weeks of doxy and you’re cured, whether your symptoms are gone or not, which… she’d had the 2 weeks of doxy, and her symptoms and her son’s symptoms were not gone. And so, I absolutely just purchased everything I could find. Nothing would work. I mean, I could name names of products, and you would recognize them, because they’re still out there today. Dr. Deb 5:28Which is. David Jernigan 5:30Kind of a… A sad thing that natural medicine is still riding on these things that have the most marketing. Dr. Deb 5:37As opposed to sometimes the things that actually have the documented research. David Jernigan 5:42Behind it, and I am a doctor of chiropractic medicine, and I specialized all these years in chronic, incurable illnesses of all types. That may sound odd to a lot of people, but doctors of chiropractic medicine are trained just like a GP typically would be. The medical schools, as I understand it, got together, decades ago and said, wow, if all we did was… Crank out general practitioners for the next 10 years, we wouldn’t have still enough general practitioners to supply the demand. Dr. Deb 6:17Right. Everybody in medicine, in medical schools, wanted to be a specialist, because that’s where the money was, and it was… David Jernigan 6:24Easier, kind of, also, to… you know, just focus on one part of the body, and specialize in that. Dr. Deb 6:31Expert in that one area. David Jernigan 6:32So we all now have the same training. We all go through pre-med. We got a bachelor’s degree, I got my bachelor’s degree in nutrition, and through, Park University in Parkville, Missouri. And so, you know, when I ran out of options to purchase, I just used a technology that I developed, which was an advancement upon other technologies, but I called it bioresonance scanning. And I coined the term back in the 90s. It was a way to kind ofKind of like a sensitive test, you know, like you might. Dr. Deb 7:09I wouldn’t. David Jernigan 7:09Of applied kinesiology, then clinical kinesiology, then chiro plus kinesiology, then, you know, you can just keep going with all the advancements that were made. Well, this was an advancement upon those things, so… I developed… I was the first in… in… my known world of doctors to develop a way to detect adjunctively, obviously we can’t say it’s a primary diagnosis. Adjunctively detect the presence of a given specimen. So we could say, thus saith my test. It’s highly likely you have Borrelia burgdurferi. And, but I had to have the specimen on hand to be able to match what I call frequency matching to the specimen. Brand new concept in those days. And so I was able to detect whether or not my treatments were successful or not. This is something even now that’s really difficult for doctors, because antibody tests, even the most advanced ones, it’s still an antibody test. It’s still an immune response to an infection.And accurately, you know, some doctors will slam those tests, saying, well. That doesn’t mean you actually have the infection, that just means your body has seen it before, which is a correct statement, kind of. So being able to detect the presence, and even where in the body these infections are was a way huge advancement in the 90s, for sure it’s kind of funny, I think about a conference I went to, and cuz… I’m kind of jumping ahead. Because I ended up developing my own formula, just for this woman and her children, and it worked. And I was like, wow! Their symptoms were gone, all the blood tests came back negative. In those days, we were using the iGenX. Western blot, eventually. And the, what was called a Lyme urine antigen test. I don’t know if you remember that, because it… Only decades later did I meet, the owner of iGenX, Nick Harris. Dr. Deb 9:17Person. And I was like, whatever happened to the Luwat test? Because I took it off the market after a while. He said, honestly, we lost the antigen and couldn’t find it again. Oh, no. David Jernigan 9:27And so… but that was a brilliant test. It was the actual gold standard in those days. Again, the world… it can’t be understated how different the world was in the 90s. Dr. Deb 9:40Yeah. David Jernigan 9:41Towards natural medicine, even. Dr. Deb 9:44Oh, yeah. We think… we think it’s bad now, but, like, when I started, too, I started in the early 2000s, like, we were all hiding under the radar, like, you didn’t market, we would have never been on social media, we didn’t run ads, we didn’t do any. David Jernigan 10:00Right. Dr. Deb 10:01Because the medical boards were coming for us. David Jernigan 10:04Came after me. Dr. Deb 10:05Because I had the word Lime on my page, my website. David Jernigan 10:10You know, not saying that I treat Lyme. Dr. Deb 10:13Hmm? David Jernigan 10:13Yes Dr. Deb 10:15Just talking about mind. David Jernigan 10:16And it’s funny, because, once I had this formula, it was something… and I trained in Germany, in anthroposophical medicine, and they’ve been trained in herbal… making herbal extracts, making homeopathic remedies in the anthroposophical methodology, and I trained with the Hahnemann versions of homeopathy, which is just slightly different. Yeah. And, so I was well-versed with making some of my own formulas by that time. And so, it was really something that I wrote on the bottle, you know, and I had to call it something, so I called it Borreligin, which is still in existence, and it’s still a phenomenal herbal remedy right now. And to my knowledge, it’s the only frequency-matched herbal formula. Maybe still out there. Because unless you knew how to do my testing, the bioresonent scanning, there was no way to actually do frequency matching. Matter of fact, as a really famous herbalist attacked me online, saying, oh, none of these herbs will kill anything. And I’m like, that wasn’t what I was saying. I was saying, back in those days, I was saying, well, if… what would the body need to address these infections?You know, not, like, what’s gonna kill the infections for the body. Dr. Deb 11:38Right. David Jernigan 11:39Right? So it was a phenomenal way, but the LUAT test was amazing because what you’d do is you would give your treatment, like an MD would give an antibiotic for a week, ahead of time. Trying to increase the number of dead spirochetes showing up in your urine one day out of 3 days urine catch. So you’d wake up in the morning, you’d collect your urine 3 days in a row, and any one of those being positive is a positive. But it was a brilliant test because it wasn’t an antibody test. They were literally counting the number of dead pieces of Lyme bacteria in your urine. I mean, it was pretty irrefutable. So I had a grand slam on the… the Western blot on patients, and I’d also have a grand slam on the LUAT, and their medical doctors would say, oh, that doctor in the lab are probably in cahoots change some lab. Dr. Deb 12:38Of course. David Jernigan 12:39That come in. And I still see that today. You know, it’s like, oh my gosh, the better the tests are getting. There’s still a bias if you do your own research. Well, if you happen to be a doctor who loves research. And you’re a clinician, so you actually treat patients who’s gonna write the research study? Well, of course, the doctor who did the study, well, he’s biased, and I’m like, I still can’t influence lab tests. Well, lab tests aren’t everything. People scream over the internet at me. It’s like, well, a negative lab test doesn’t mean anything. I was like… I get that with the old Western blot testing. Dr. Deb 13:16Right. David Jernigan 13:16The more sensitive tests, which are very close to 100%, Sensitivity, and 100% specificity. So, meaning, like, they can… if you have the infection, they’re gonna find it. Dr. Deb 13:30They’ll find it, yeah. David Jernigan 13:31And if they… if you have the infection, they’re going to be able to tell you exactly 100% correctly what kind of infection it is. Back in those days, you couldn’t, you could just count the dead pieces, which was… Dr. Deb 13:43Yeah. David Jernigan 13:43Significant, but It’s funny, because when medicine does that, you know, mainstream medicine that’s backed by all the nice foundations who donate millions of dollars towards the research. Their negative tests are significant, but if you fund your own, Yours isn’t that significant. Dr. Deb 14:04Right, or what if we call something a seronegative autoimmune disease, like lupus or rheumatoid arthritis, because none of the tests are positive, but you have all the symptoms. Here, let me give you this $100,000 a year drug. David Jernigan 14:19Yeah. Dr. Deb 14:19And instead of looking for what might actually be causing the symptoms. That’s all okay, but what we do is not okay. David Jernigan 14:27Right. Yeah, it’s a double standard, and it’s getting better. I want to do… tell the world it is getting better. Some of the dinosaurs are retiring. Dr. Deb 14:36No. David Jernigan 14:37Way for people who are… Are more open-minded to new ideas. But, getting back to that woman, she… that formula that I made just for her and her son, I… She went online. Dr. Deb 14:54Which, I had never been on a news group. David Jernigan 14:58Not even sure I knew what one was, you know? Imagine, I’m kind of that dinosaur that… Cell phones were, like, these really big things with a big antenna sticking out of it, and… Dr. Deb 15:09Nope. David Jernigan 15:10So I thought I was pretty hot stuff, just that I actually had a computer software program that was running my front desk. And even then, it was an Apple IIe computer. Dr. Deb 15:21Right. David Jernigan 15:22Probably be pretty valuable right now if I’d kept it, but… Dr. Deb 15:25Mmm… David Jernigan 15:26It being an antique. But, suddenly people were calling my clinic, because the lady with the twin boys that was well was telling people on these research, I mean, these Lyme disease forums and boards online. And, I started going, oh my gosh, you know, as a doctor, it’s one thing to treat a person in your clinic, it’s a different thing to have your clinic name on the label. Like, we all do, Even now, and you’re supposed to write everything that’s on the label, and… all these guidelines, and I’m like, wow, I need to split this off. I mean, I def… I definitely want to help people, and this is… I was pretty excited about the results we were getting. Pre-treat… Pre-treatment and post-treatment. And, so… that’s where I developed, my nutraceutical business in the 90s called Journey Good Nutraceuticals. My advice to anybody thinking about doing the same thing, don’t put your last name on it. Dr. Deb 16:25– David Jernigan 16:25You know, because anytime negative anything comes out, there goes the Jernigan name, you know, the herbal, you know, there’s just all these, and especially nowadays, with all the bots that are just designed to slam natural medicine. Dr. Deb 16:38Yeah. David Jernigan 16:39And that is out there in a… and just ugly people. Dr. Deb 16:42Or should we just say, people with a different opinion? How’s that? David Jernigan 16:46Yeah. That are being less than supportive. Dr. Deb 16:49But. David Jernigan 16:51It was amazing, because by 1999, I presented my research, my first research, I’d never done research. This is what I would… I would say to a lot of people who go, my doctor did… I don’t know, my doctor doesn’t know what you’re doing, my doctor… I was like going, you know, most doctors don’t do research. They don’t publish anything. Their opinion is their opinion, but they don’t back it up in peer review, right? And so that’s what I always tried to do, was back it up in peer review and publish. And so, in 1999, I presented at the International Tick-Borne Diseases Conference in New York City. I’m telling you, it was like the country boy going to the city, you know, I got my… I got my suit on, and I looked all right, and my booth was wonderful, and all these different things, and it was just a big wake-up call.Because what we had demonstrated… let’s get back to the… and this was what I demonstrated with that first study. was that… A positive LUAC test, that Lyme urine antigen test for my Gen X, was a score of 32. Meaning, one of those 3 mornings urine had 32 pieces in the amount of urine they checked of deadline bacteria spirochetes. Okay? Okay. With antibiotic challenges, a highly positive was a score of 45. Dr. Deb 18:19Wow when I would give one dropper 3 times a day for a week. David Jernigan 18:24Ahead of time, and then do the person’s LUAT test, We were getting scores 100, 200… And at that point, we only had a couple, but we had a couple that were greater than 400. Yeah, dead pieces, where the lab just quits counting. They just said, somewhere over 400, right? Dr. Deb 18:45Yeah. David Jernigan 18:46Which, when the medical system at the conference, you know, I was the only natural doctor in the world that was… had any kind of proof of anything naturally that could outperform antibiotics. Can you imagine? Dr. Deb 18:59Yeah. And… David Jernigan 19:01They were just, oh my gosh, incredulous. They’re like, I’ve given the most… one guy came up to me, and to my face, and he goes, I’ve given the most aggressive antibiotic protocols And I’ve only seen one patient over 100. I was like, that makes this pretty significant, doesn’t it? But, it didn’t just, like, make us take off, because guess what? In Lyme world, if a pharmaceutical antibiotic made you feel horrible. That meant it was working. Dr. Deb 19:28That’s right. We used to, back in the day, if you didn’t herx. And had that horrible die-off reaction, for those of you who don’t know what a herx is, but if we didn’t make you herx, we weren’t doing our job right. David Jernigan 19:40You’re looking for your patients to feel horrible, and sometimes to the level of committing suicide. Dr. Deb 19:46Yes. David Jernigan 19:47So bad. Dr. Deb 19:48Yes. David Jernigan 19:49And I was the first doctor, I think, in the world to start screaming and hollering and saying, stop using the worsening of your patient’s symptoms as a guide to good treatment, because they’re… I wasn’t seeing it with my formulas. Because I was doing a comprehensive program of care. I think I was also one of the first doctors to say, we need to detoxify these people as we’re doing this. And you would sit there and say, well, sure you were. I was like, well, remember, there wasn’t a lot of communication. There wasn’t anybody on the internet saying, do this, do that. And, It was, it was interesting in those days. It was, how do you… How do you help the world heal from these things? That they don’t know they have. So later, I actually had a beautiful booth at a health… a big health expo in Texas, I remember, and I was like, you know, you spend a lot of money on the booth, and… Dr. Deb 20:43Yup. David Jernigan 20:43And you’re thinking about it because you’re funding the whole thing, you say, wow, if I only sell one case, I’ll at least cover my cost. Dr. Deb 20:51Yep. Yeah, you’re great. David Jernigan 20:52And I had this beautiful banner of, like, a blown-up tick’s mouth under microscope. You know those beautiful pictures of, like, all the barbs sticking out, and how they anchor themselves in your skin, and… And, thousand people walking by my booth, and they’re just like, keep walking, because they didn’t know they had Lyme. There was, like, and they had MS, maybe, but they don’t have Lyme, and so they just would keep walking. Nobody even knew. Why would I go to a conference in Texas? And I’m trying to say, no, guys, it’s everywhere. Dr. Deb 21:24Yeah. David Jernigan 21:24And… and everybody, you know, yes, you probably have this, you know, kind of thing. If you’re… if you… are chronically ill, almost, of any kind of way. You know, kind of trying to tell people this was… Again, in Robin’s pathology textbooks, one of the few things that it did tell you about Lyme was that it was called the Great… the New Great Imitator. Because it would imitate up to 200 or more different illnesses. So, it’s been an interesting journey, of… educating people, writing articles, but it was interesting, the lady who I first fixed, Laboratory verified, everything like that, symptoms went away, all that kind of fun stuff. Her children were fine, they’ve been fine for years now. When she went on the newsboards in the Lyme disease support groups, It created a war. Oh my goodness, it was like, how dare you? And, say that something natural might actually help, right? Dr. Deb 22:30Right, exactly. David Jernigan 22:32And, I even had… A… one of those first calls to… with a marketing company at one point, way a long time ago. And the lady got on the phone, the owner of the marketing company goes, I would have blood on my hands if I actually took your clinic on. Yeah, you can’t treat Lyme disease, and… Even the big, big associations that are out there are still largely that way. I mean, they’re getting better, but it’s just like… you know, a lot of the times, it’s herbs are good. Herbs will help. Good, you know, but they’re safe. So, it’s still a challenge to… to… present in mainstream Lyme communities, even. Because there’s this… Fear of doing anything outside of antibiotics. Dr. Deb 23:32Yeah, so let me ask you this. From your perspective. Why do you think so many chronic infections exist these days, like Lyme and the co-infections, Babesia, Bartonella, mold illness? And we talked a little bit about herbs and why they, antibiotics and things like that fail, but let’s talk a little bit about that. David Jernigan 23:53So, it’s fascinating. When I trained in Germany, they said that we, as humanity, has moved away from what they called the inflammatory diseases. You know, in the old days, it was. Lots of high fevers, purulent, pus-generating bacterial infections. And I said, as a society, we have… Dr. Deb 24:14Have shifted from those to what they call cold sclerotic diseases, which are your… David Jernigan 24:21Cancers, your diabetes, your atherosclerosis, your… and they said, we’re starting to see what used to only be geriatric diseases in our children. That’s how bad it’s gotten. We have suppressed fevers, we don’t… we don’t respect the wisdom of the human body. So, you know, the doctors say, step aside, body, I will fix this infection for you with this antibiotic. And so, what we’ve done with the, overuse of antibiotics, and this isn’t me just talking from a natural perspective, this is… Right, it’s everybody around the world is acknowledging. I’ll show you… I could show you a, a presentation, if we can do a screen-sharing situation. Yeah. About the antibiotic situation in the world, because it’s really concerning. But what I would say, and kind of like an advancement forward, is we are seeing mutated bacteria. You know, they talked about… do you remember when they found the Iceman, you know, the… You know, the prehistoric guy that’s… In the eyes, and he had Lyme bacteria. I was like, he had spirochetes, maybe. Dr. Deb 25:33Yeah. David Jernigan 25:33That isn’t a modified, mutated version. That’s just maybe the… Lyme… you know, Borrelia… call it Borrelia something, you know, it’s a spirochete, but what we’re dealing with today. Even under strep or staph, as you know, you know, Pseudomonas aeruginosa, you name it, whatever kind of infection a person has is not the same bacteria that your grandparents dealt with. Dr. Deb 26:01That’s right. David Jernigan 26:32It’s a much mutated, stronger, more resistant to treatment type of thing. So, I think that’s one reason. I think the, It’s great that we’re seeing, you know, Secretary Robert F. Kennedy Jr. bringing awareness to things that Like it or not, yeah, seed oils do create inflammation, and everyone in the natural realm, as you know. Has been trying to say this for probably how long? Dr. Deb 26:35Yeah, 25, 30 years. 20 years each. David Jernigan 26:48Yes. You know, thank goodness for people like Sally Fallon and her beautiful book, Nourishing Traditions, that started you know, Dr. Bernard Jensen’s books way back in the day, Dr. Christopher’s books way back in the day. Dr. Deb 26:48Damn. David Jernigan 26:49You know, all of them were way ahead of their time, saying, by the way, your margarine is only missing one ingredient from being axle grease. Dr. Deb 26:58Yeah. David Jernigan 26:58I think that was Dr. Jensen saying that at one point, probably 50, 60 years ago, I don’t know. Dr. Deb 27:03Yep. David Jernigan 27:04So, we’ve created this monster. We, we live in a very controlled environment, you know, of 72, 74 degrees at all times, we don’t sweat, we don’t have to work that hard, typically. You know, most of us aren’t out there like our ancestors were, so that’s making us more and more… Move towards the cold sclerotic diseases, of which even Lyme disease is, you know, which… Yes, it has inflammation, yes, but as a presentation, it’s very often associated with some of these Cold sclerotic diseases of mankind that we see now. Dr. Deb 27:46You have it. David Jernigan 27:47Yeah. Dr. Deb 27:48So, tell me, what is phage therapy? David Jernigan 27:52Well, may I show you a cool video? Dr. Deb 27:55Yeah, I’d love that. David Jernigan 27:56I did not make this video, this is just one of my favorites, because it’s from the National Institute of Health. Let’s see if I can just… Click the share screen thing. And get that to pop up. That’s not what I’m looking for, but it’s gonna be soon. Let’s go here… Alright, can you see that? Dr. Deb 28:18Yeah. David Jernigan 28:19Okay. Modern medicine faces a serious problem. Thanks in part to overuse and misuse of antibiotics, many bacteria are gaining resistance to our most common cures. Researchers are probing possible alternatives to antibiotics, including phages. So, bacteriophages, or we like to call them phages for short, are naturally occurring viruses that infect and kill bacteria. The basic structure consists of a head, a sheath, and tail fibers. The tail fibers are what mediate attachment to the bacterial cell. The DNA stored in the head will then travel down the sheath and be injected inside the cell. Once inside the cell, the phage will hijack the cellular machinery to make many copies of itself. Lastly, the newly assembled phages burst forth from the bacterium, which resets their phage life cycle and kills the bacterium in the process. Someday, healthcare providers may be able to treat MRSA and other stubborn bacterial infections using a mixture of phages, or a phage cocktail process would be first to identify what the pathogen is that’s causing the infection. So the bacterium is isolated and is characterized. And then there’s a need to select a phage in a process known as screening of phage that are either present in a repository or in a so-called phage library. That allows for many of the phages to be evaluated for effectiveness against that isolated I don’t know, bacterium. Phages were first discovered over 100 years ago by a French-Canadian named Felice Derrell. They initially gained popularity in Eastern Europe, however, Western countries largely abandoned phages in favor of antibiotics, which were better understood and easier to produce in large quantities. Now, with bacteria like these gaining resistance to antibiotics, phage research is gaining momentum in the United States once again. NIAID recently partnered with other government agencies to host a phage workshop, where researchers from NIH, FTA, the commercial sector, and academia gathered to discuss recent progress. NIH… So… That is… That is what phage therapy in… is. in what I call conventional phage. Let’s see, how do I get out of the share screen? Hope you already don’t see it. Dr. Deb 30:58Yep, at the top, there should just be a button. David Jernigan 31:00I don’t. Dr. Deb 31:00Stop sharing, yeah. David Jernigan 31:01So… Conventional phage therapy, as you just saw, is a lot like what it is that we’re doing, only the difference is they’re taking wild phages from the environment. They’re finding phages anywhere there’s, like, a lot of bacteria. And then they isolate those phages, and like he said, the gentleman at the very end said we put them in a library, and so there are banks of phages that they can actually now use, and One of the largest banks that I know of has about 700 different bacteriophages, or phages. In their bank that they can pull from. Dr. Deb 31:43Wow. Do you want to take a guess? David Jernigan 31:46How many bacteriophages they’ve identified are in the human gut, on average? Dr. Deb 31:52Oh my god, there’s gotta be more… David Jernigan 31:53Kinds, different kinds of phages, how many? Dr. Deb 31:56There’s gotta be millions. David Jernigan 31:57Well… In population, there’s… humongous numbers, numbers probably well beyond the trillions, okay? Hundreds of trillions, quadrillions, maybe, even. But in the gut, a recent peer-reviewed journal article said that there were 32,242 different types of bacteriophages that live naturally in your intestines, your gut. Dr. Deb 32:25Boom. David Jernigan 32:2632,000. Okay, so… If you read any article on phage therapy that’s in peer review, almost every single one in the very first paragraph, they use the same sentence. They go, Phages are ubiquitous in nature. They’re ubiquitous in nature. So my brain, when I find… when all this finally clicked together, and when we clicked together 5 years into my research, I could not get it to work for 5 years. I just kept going. But that sentence really got me going. I was, like, going, you know. If you look at what ubiquitous means, it says if Phages were the size of grains of sand. Like sand on the beach. They would completely cover the earth and be 50 miles deep. How crazy is that? Dr. Deb 33:24Wow. David Jernigan 33:25That’s how many phages are on the planet. There’s so many… they outnumber every species collectively on the planet. So, it’s an impossibility in my mind. I went, huh, it’s an impossibility that… You catching a, a sterile Bacteria, it’s almost an impossibility. Since the beginning of time, phages have been needing to use a reproductive host. And it’s very specific, so every kind of bacteria has its own kind of phage it uses as a reproductive host. Because phages are… and this is a clarification I want to make for people. just like in the old days, we were talking about the 90s, I talked to a veterinarian that had gotten in trouble with the veterinary board in her state. Dr. Deb 34:14Back in the old days. David Jernigan 34:16Because she gave dogs probiotics. And the board thought she was giving the dogs an infection so that she could treat them and make money off of the subsequent infection. Dr. Deb 34:28Oh my god. David Jernigan 34:29Nobody actually had heard of good, friendly bacteria in the veterinary world, I guess she said she had gotten in trouble, and she had to defend herself, that, no, I’m giving friendly, benevolent, beneficial bacteria. Okay, to these animals, and getting good results.So, phages… Are friendly, benevolent, beneficial viruses. That live in your body, but they only will infect a certain type of bacteria. So… What that means is if you have staff.Aureus, you know, Staphylococcus aureus bacteria. That bacteria has its own kind of phage that infects it called a staph aureus phage. E. coli has an E. coli phage. Each type of E. coli has its own phage, so Borrelia burgdurferi has its own Borrelia burgdurferi type of phage, whereas Borrelia miyamotoi alright? Or any of the other Borrelia species, or the Bartonella species, or the… you just keep going, and Moses has its own type of phage that only will infect that type of bacteria. So that’s… You know, when you realize, wow, why are we going to the environment Was my thought. Dr. Deb 35:54Yeah. David Jernigan 34:55Trying to find wild phages and put them into your body, and hopefully they go and do what you want them to do. What if we could trigger the phages themselves that live in your body to, instead of just farming that bacteria that it uses as a host, because what I mean by farming is the phages will only kill 40% of that population of bacteria a day. Dr. Deb 36:20Wow. David Jernigan 36:20And then they send out a signal to all the other phages saying, stop killing! Dr. Deb 36:24It’s like. David Jernigan 36:2560% of the bacteria population left to be breeding stock. It’s kind of like the farmer, the rancher, who… he doesn’t send his whole herd to the butcher. Dr. Deb 36:35Right. David Jernigan 36:36Just to, you know, he keeps his breeding stock. He sends the rest, right? So, the phages will kill 40% of the population every day, just in their reproduction process. Because once there’s so many, as you saw in the video, once the phage lands on top of the bacteria, injects its genetic material into the bacteria, that bacteria genetic engine starts cranking out up to 5,200 phages per bacteria. Dr. Deb 37:06I don’t know who counted all those… David Jernigan 37:08Inside of a bacteria, but some scientists peer-reviewed it and put it out there. that ruptures, and it literally looks like a grenade goes off inside of the bacteria. I wish I’d remembered to bring that video of a phage killing a bacteria, but it just goes, oof. And it’s just a cloud of dust. So, you’re breaking apart a lot of those different toxins and things. So… That’s… That was the impetus to me creating what I did. That and the fact that I looked it up, and I found out that phages will sometimes go… Crazy. I don’t know how to say it. Wiping out 100% of their host. And it could be a trigger, like change in the body’s pH levels, it could be electromagnetically done, you know, like, there’s been documentation of… I think it was, 50 Hz, electricity. Triggering one kind of phage to go… Crazy and annihilate its host population. There’s other ways, but I was, like, going, none of those fit me, you know? It’s not like I’m gonna shock somebody with a… Jumper cable or something to try to get phages to… to do that kind of thing. But the fact that it could be done, they can be triggered, they can switch and suddenly go crazy against their population. But what happens when they kill 100% of their host? The phages themselves die within 4 days. Dr. Deb 38:45Hmm. Because they can’t keep reproducing. David Jernigan 38:47There’s nothing to reproduce them, yeah. Dr. Deb 38:49Yeah. Especially… unless they’re a polyvalent phage, that means a phage that can segue and use. David Jernigan 38:54One or two other kinds of bacteria. To, as a reproductive host. But a lot of phages, if not the majority, are monovalent, which means they have one host that they like to use. And so… Borrelia, so… my study that I ended up doing, and I published the results in 2021, And it’s a small study, but it’s right in there at the high end, believe it or not, of phage research. Most phage research is less than 30 people. In the study. But, we did 26 people.And after one month of doing the phage induction that I invented, which only… Appears to only, induce or stimulate the types of phages that will do the job in your body. I don’t care what kind of phage it is. I don’t care if it’s a Borrelia phage, it may be a polyvalent phage that normally doesn’t use the Borrelia burgdurferi as its number one. Host, but it can. To go and kill that infection. And the fascinating thing is, there was a brand new test that came out at the same time I came out with the idea, literally the same weekend they presented. Dr. Deb 40:1511. David Jernigan 40:15ILADS conference in Boston in 2019. It was called the Felix Borrelia phage Test. So the Felix Borrelia phage test. Because Borrelia are often intracellular, right, they’re buried down in the tissue, they’re not often in the blood that much. And therefore, doing a blood test isn’t really that accurate. But you remember how there’s, like, potentially as many as 5,200 phages of that type erupt from each bacteria when it breaks apart. It’s way easier to detect those phages, because they’re now circulating, those 52, as you saw in the video. 5,200 different phages are now seeking out another Borrelia that they can infect. And so, while they’re out in circulation, that’s easy to find in the bloodstream. So, 77% of the people, so 20 out of 26, were tested after a 2-week period. After only a 4-day round of treatment. Because according to my testing, remember, I can actually test adjunctively to see if I can find any signatures for those kinds of bacteria. And I couldn’t after 4 days, so we discontinued treatment and waited Beyond the 4 days that would allow the phages themselves to die, so we waited about a week and a half.And redid the test. And 77%, so that 20 out of 26 of the people, were completely negative. Dr. Deb 41:50Wow. David Jernigan 41:52Which, you go, well, it’s just a blood test. Well, no, we actually had people that were getting better, like, they’d never gotten better before. We had one woman who was wheelchair-bound, and in two weeks was able to walk, and even ultimately wanted to work for my clinic. I’m just, like, going… Dr. Deb 42:07I didn’t want to write about all that. I wanted to write about the phages. I was like… David Jernigan 42:12article, I probably should have put some of those stories, because, Critics would say, well, you got rid of the infection, maybe, but… Did you fix the Lyme disease? Well, that’s… there’s two factors here that every doctor needs to understand. There’s the infection in chronic illness, there’s the infection, and then there’s the damage that’s been done. Because sometimes I have these people that would come in and say, well, Dr. Jernigan, it didn’t work for me, I’m still in the wheelchair. And I’m like, no, it worked. Repeat lab test over months says it’s gone, it’s gone, it’s gone. It’s like, we would follow, and 88% of the people we followed long-term were still negative, which is amazing to me. Dr. Deb 42:56And then they have to repair the damage. David Jernigan 42:59It’s the damages why you still have your symptoms. And that’s where the doctor has to get busy, right? Dr. Deb 43:06Right David Jernigan 43:06They were told erroneously by their doctor that originally treated them that they’d be well, they’d get out of the wheelchair, if he could actually kill all these infections. Dr. Deb 43:15It’s not true. David Jernigan 43:16Unless it’s caught early. So I love the analogy, and I’ve said it a thousand times.that Lyme disease and chronic infections are much like having termites in the wood of your house. If you find the termites early, then yeah, killing the infection, life goes back to normal, the storm comes and your house doesn’t fall down. But if it’s 20 years later. Killing the termites is still a grand idea. Right. But you have the damage in the wood that needs to be repaired as well. All the systems… when I talk about damage to the wood, I mean, like. All the bioregulatory aspects of the body, how it regulates itself, all the biochemical pathways, the metabolic pathways we all know about, getting the toxins that have been lodged in there for many years, stopping the inflammatory things that have been running crazy. Dealing with all those cytokines that are just running rampant through the body, creating this whole MCAS situation. Which are largely… Dr. Deb 44:21Coming from your body’s own immune cells called macrophages, which are not even… David Jernigan 44:26It’s not… a virus at all, it’s part of the immune system, it’s like a Pac-Man, and research shows that especially in spirochetes. There is no toxin. Now, I wrote 4 books. I think I wrote the very first book on the natural treatment of people with Lyme disease back in the 90s. Why did I write that? Not because I wanted to be famous, it’s a tiny book, actually, the first one was.I was just trying to help people get out of this idea that you will be well when you kill all the bugs. I was saying, it’s… you need to be doing this. If you can’t come to my clinic, at least do this. Try to find somebody that will do this for you. And that ultimately led to a bigger book.as I kept learning more, and I was like, going, well, okay, now at least do this amount of stuff. And you need to make sure your doctor is handling this, this, this, and this. And so, the third book was, like, 500 and something pages long. And then the fourth book was 500 and something pages long, and now they’re all obsolete with the whole phage thing, because this just rewrites everything. Dr. Deb 45:34Yeah. David Jernigan 45:34It’s pretty fascinating. Dr. Deb 45:37Do you think the war on bugs, mentality created more chronic illness than it solved? David Jernigan 45:44Because of the tools that doctors had to use, yes. We’re a minority, we’re still a minority, you and I. Dr. Deb 45:54Yep. Our doctoring… David Jernigan 45:56Methods I never had, and you’d never… maybe you did, but I’d never had the ability to grab a prescription pad and write out a prescription. I had to figure out, how do I get… and this was… and still my guiding thing, is like, how do I identify, number one, everything that can be found that’s gone wrong in the human body. And what do I need to provide that body? Like, the body is the carpenter. That has to do the repair, has to regenerate, has to do everything, has to get… everything fixed right? We can’t fix anything. If you have a paper cut, there isn’t a doctor on the planet that can make that go away. Dr. Deb 46:38Right. David Jernigan 46:39Of their own power, much less chronic illnesses. So, all the treatments are like the screws, saws, hammers, you know the carpenter must be able to use. So a lot of the time, doctors are just throwing an entire Home Depot on top of the carpenter. In the form of, like, bags of supplements, you know, hundreds of supplements, I’ve seen patients walk in my door with two suitcasefuls. And they were taking 70 bottles, 65 to 70 bottles of supplements, and I’d be just like, wow, your carpenter who’s been working for 24 hours a day, 7 days a week. He’s exhausted. There’s chaos everywhere, you don’t know where to. Dr. Deb 47:22Starting. David Jernigan 47:22He goes, you want me to do what with all this stuff? Dr. Deb 47:25Yep, I’ve seen the same thing. People… thousands, you know, several thousand dollars a month on supplements, and not any better. But they’re afraid to give up their supplements, too, because they don’t want to go backwards, either, and… there’s got to be a better way on both sides, the conventional side and the alternative side, although you and I don’t say it’s alternative, that’s the way medicine should be, but… David Jernigan 47:48Right. Dr. Deb 47:49We have to have a good balance on both sides. David Jernigan 47:52And I will say, too, in defense of doctors using a lot of supplements, I do use a lot of supplements. Dr. Deb 47:57Yeah, I do too. David Jernigan 47:58but I want to synergize what I’m giving the patient so that the carpenter isn’t overwhelmed and can actually get the job done. Like, everything has to work harmoniously together, so it’s not that… It’s not the number of supplements, and why would you need a lot of supplements? Well, because every system in your body is Messed up. My kind of clientele for 30 years. Our clientele, yours and mine. Dr. Deb 48:25Yeah. David Jernigan 48:26They have been sick, For decades, many of them. Dr. Deb 48:31Yeah. David Jernigan 48:31And if they went into a hospital, they honestly need every department. They need endocrinology, they need their kidney doctor, they need their… They’re a cardiologists, they need a neurologist, they need a rheumatologist. I mean, because none of those doctors are gonna deal with everything. They’re just gonna deal with one piece of the puzzle. And if they did get the benefit of all the different departments they need, yeah, they’d go out with a garbage bag full of stuff, too. Dr. Deb 48:57Hey, wood. David Jernigan 48:58Only, they’re not synergized. They don’t work together. You’re creating this chemistry set of who knows how much poison. And I want to tell your listeners, and I mean, you probably say this to your patients as well. There is a law of pharmacy that I learned eons ago, and it applies to natural medicine, too. Dr. Deb 49:21Yep. David Jernigan 49:22But the law says every drug’s primary side effect Is its primary action. So, if you listen to TV, you can see this on commercials. I love… I love listening to these commercials, because I’m like, wow. let’s… let’s… I don’t want to say I’ve named Brandon. I don’t know if that’s…Inappropriate to name a name brand, but let’s just say you have a pharmaceutical that is for sleep. After they show you this beautiful scene of the person restfully sleeping and everything like that, they tell you the truth. It’s like, this may cause sleepiness… I mean, sleeplessness. Dr. Deb 50:04Yeah. David Jernigan 50:04Found insomnia. Dr. Deb 50:06And headaches, and diarrhea. David Jernigan 50:08All the other things, and if it’s an antidepressant, what does the commercial do after it finishes showing you little bunny foo-foo, jumping through a green, happy people? They tell you, this may create depression, severe depression, and suicidal tendencies, which is the ultimate depression. So, I want everyone to understand you need to figure out what your doctor’s tools are that they’re asking you to take, and they’re wanting you to take it forever, generally in mainstream medicine, right? In the hospitals and everything. They don’t say, hey, your heart has this condition, take this medicine for 3 months, after which time you can get off. Dr. Deb 50:48Yep. David Jernigan 50:49not fixing it, right? So… That, on a timeline, there is a point, if it was truly even fixing anything. That you… it’s done what it should do, and you should get off, even if it’s a natural product. It’s just like. Dr. Deb 51:03Right David Jernigan 51:03It’s done what it should do, and you should get off, but instead. you go through the tree… the correction and out the other side, and that’s where it starts manifesting a lot of the same problems that it had. So, anti-inflammatories, painkillers, imagine the number one side effects are pain inflammation. So, the doctor says, well. If you say, hey, I’m having more pain, what does he do? He ups the dosage. And if he… if that doesn’t work, if you’re still in a lot of pain, which he would be, he changes it to a more powerful thing, right? But it starts the cycle all over again. So when you ask me, it’s like, why are we having so much chronic illness? It’s because of the whole philosophy. is the treatment philosophy of mainstream medicine that despises what you and I do. Because we’re… our philosophy from the start is the biggest thing. It’s like… We’re striving for cure. That dirty four-letter word, cure, we’re not even supposed to use it. And yet, if you look it up in Stedman’s Medical Dictionary, it just means a restoration of health. Remission. Everyone’s like, oh, I’m in remission. I’m like, remission is a drug term. It’s a medical term. Again, look it up in a medical dictionary. It is a pharmaceutical term for a temporary pause Or a reduction of your symptom, but because it’s just… symptom suppression, it will come back. It’s… remission is great, I suppose, in… At the end of, like, where you’ve exhausted everything, because I can’t fix everything, I don’t know about you. Dr. Deb 52:41No, I can’t either, yeah. David Jernigan 52:43you know, on my phone consults, I try to always remind people, as much as I get excited about my technologies gosh, I see so much opportunity to fix you. I always try to go, please understand, I’m gonna tell you what most doctors may not tell you on a phone consultation. I can’t fix everything. Dr. Deb 53:03Yeah. David Jernigan 53:03For all of my tricks, I can’t fix everything. Not tricks, but you know, all my technologies, and all my inventions. Phages, too. They are a tool. You know, antibiotics. I think I wrote a blog one time, it should be on my website somewhere, that says, Antibiotics do not… fix… neurological disease, or… I don’t know, something like that. You know, you’re using the wrong tool. I mean, it does what it does. Dr. Deb 53:32Yeah, you’re using a hammer to do what a screwdriver needs to. David Jernigan 53:35Yeah, you know, it’s like it’s… And yet, you can probably tell her… that you’ve had patients, too, that they go, Dr. Jernigan. My throat was so sore, and as soon as I swallowed that antibiotic. I felt better, and I’m, like, going… How long did it take? Oh, it was immediate! I was like, dude, the gel cap didn’t even have time to dissolve, I mean… Dr. Deb 53:58SIBO. David Jernigan 54:00But, it’s not going to repair the tissues that were all raw. kind of stuff. So, I mean, that ulceration of your throat that’s happening, the inflammation, there’s no anti-inflammatory effect of these things. So, I digress a little bit, but phages, too… I wrote an article that’s on the website, that’s setting healthy expectations for phages, because they want… we can see some amazing things happen, things that in my 30 years, I wish I had all my career to do over again, now having this tool. It’s just that much fun. I… when doctors around the country now are starting to use our inducent formulas, there’s, 13 of them now, formulas. For different broad-spectrum illness presentations. I tell them all the same thing, I was like, you are gonna have so much fun. Dr. Deb 54:53That’s exciting. Women. David Jernigan 54:54Winning is fun, you know? I was like. You know, mainstream medicine may never accept this, I don’t know. I feel a real huge burden, though, to do my best to follow a, very scientific methodology. I’ve published as much as I can publish at this time by myself. I never took money from the… the sources that are out there, because what do they do? They always come… money comes with strings. Dr. Deb 55:22Yes, it does. David Jernigan 55:23I don’t trust… I don’t trust… I mean, if you listen to the, roundtable that Our Secretary Robert F. Kennedy Jr. Dr. Deb 55:35Yeah. David Jernigan 55:36On Lyme disease last week the first couple of speakers were, like, pretty legit. I mean, all of them were legit, but I mean, they were, like, senators and congressmen or something like that, I think. And then you have… RFK Jr. himself, who’s legit. Yeah they were fessing up to the fact that, yes, they were suppressing anything to do with Lyme. Dr. Deb 56:00Yeah. David Jernigan 56:00Our… our highest levels of, marbled halls and pillars and… of medicine were doing everything the way I thought they were. They were suppressing me. I was like, how can you ignore the best formulas ever, and still, I think Borreligen, and now, induced native phage therapy are still, I believe, I don’t… I’ve never seen it, I could be wrong. The only natural things that have been documented in a medical methodology. Dr. Deb 56:34Hmm in the natural realm. I mean, all the herbs that we talk about. David Jernigan 56:39You know, there’s one that was really famous for a while, and it said, we gave… so many patients. This product, and other nutritional supplements. And at the end, X number of them were… dramatically better. That’s not research. Dr. Deb 56:57Right. That’s observation. David Jernigan 56:59The trick there was we gave this one thing, and then we gave high-dose proteolytic enzymes, we gave high dose this, we gave high dose that, but at the end of the study, we’re going to point back at the thing we’re trying to sell you as being what did it. Dr. Deb 57:12Which is what we do in all research, pretty much. David Jernigan 57:15Well… Dr. Deb 57:16tried to… David Jernigan 57:17Good guys, I hope. Dr. Deb 57:18Do the way we want, right? In… in conventional… David Jernigan 57:22Yeah. Dr. Deb 57:22Fantastic David Jernigan 57:23Very often, yeah, in conventional medicine, definitely. Yeah. And, it’s kind of scary, isn’t it, how many pharmaceuticals are slamming us with, because they’re… Dr. Deb 57:33Okay. David Jernigan 57:34There’s a new one on TV every day, and there’s. Dr. Deb 57:36Every day, yes. David Jernigan 57:37It’s like, who comes up with these names? They’re just horrible. Dr. Deb 57:40Yeah, you can’t pronounce them. David Jernigan 57:41I want to be a marketing company and come up with some Zimbabwehika, or something that actually they go with, and I’m like, I just made a million bucks coming up with it. I’ll be glad when that’s not on the TV anymore, which… Oh, me too. Me too. Dr. Deb 57:54Dr. Jaredgen, this was really wonderful. What do you want to leave our listeners with? David Jernigan 58:00Well, you know, everyone’s calling for a new treatment. Dr. Deb 58:05Yeah. You bet. David Jernigan 58:08I have done everything I can do to get it out there, scientifically, in peer review, so that if you want to look up my name. Dr. Deb 58:16I published an open access journal so that you didn’t have to buy the articles. Like, PubMed, you have to be a member. If you want to look at a lot of the research, you have to buy the articles. David Jernigan 58:26I’ve done everything open access so that people had access to the information. I honestly created induced native phage therapy to fix my own wife. I mean, I… I was… I used to think I could actually fix almost anything. Gave me enough time. And, I could not fix her. You know, the first 10 years, she was bedridden. Dr. Deb 58:49Wow. David Jernigan 58:50People go, oh, it’s easy for you, Dr. Jernigan, you’re a doctor. Dr. Deb 58:54Oh yeah, right? Yeah. David Jernigan 58:56Oh my gosh, how many tears have been shed, and how much heartache, and how much of this and that. I mean, 90% of our marriage, she was in, bed, just missing Christmas. All the horror stories you hear in the Lime world, that was her, and I could not get her completely well. And, she’s a very discerning woman. I say that in all my podcasts, because it’s. Dr. Deb 59:19Just… David Jernigan 59:16Amazing. It’s like, every husband, I think, should want a wife that’s… Always, right? Not that you surrender your own opinion, but it’s like, it’s… it was literally, I don’t know what, 6 months before the ILADS conference in Boston in 2029… in 2019 that She said, are you going to the ILADS conference this year? And I’m like, I’ve been going for, like, 15, 20 years, however long it’s been going on, and I was like, I’m not gonna go to this one. And, 3 days before the conference, she says, I think you should go. And I go, okay. Like I say, she’s generally right. And that… I bought a Scientific American magazine at the newsstand in the Nashville airport. Started reading a story about phages in that that copped that edition of the Scientific American, and It was a good article, but it wasn’t super meaty, you know. very deep on those, but I just was stimulated. Something about being at elevation. Dr. Deb 1:00:02Yeah. Your own mountains, I don’t know, I get all inspired. David Jernigan 1:00:25And I wrote in the margins and highlighted this and that until it was, like, ultimately, I spent the entire conference hammering this out. And it worked. And it’s been working, it’s just amazing. It’s… We’re over 200 different infections that we’ve… we’ve clinically or laboratory-wise documented. There’s a new test for my GenX called the CEPCR Lyme Panel. like, culture. 64 different types of infections, and I believe right now the latest count is something like 10 for 10 were completely negative. Dr. Deb 1:01:03Wow. David Jernigan 1:01:03These chronically infected people. And so, that hadn’t been published anywhere. So, in my published article, remember I was talking about that 20 out of the 26 were tested as negative for the infection? That doesn’t mean they’re cured, okay? Remember, they’re chronically damaged. That’s how we need to look at it. Dr. Deb 1:01:23funny David Jernigan 1:01:24damaged. You’re not just chronically infected. And, but with 30-day treatment.24 out of the 26 were tested as negative. Dr. Deb Muth 1:01:34That’s amazing. David Jernigan 1:01:35So 92% of the people were negative.Okay? The chances of that happening, when you run it through statistical analysis.The chances… when you compare the results to the sensitivity percentages, you know, the 100% specificity and 92% sensitivity of the…Of the lab testIt’s a 4.5 nonillion to 1 chance that it was a fluke. Isn’t that amazing? Now, nearly… I’m not even sure how many zeros that is, but it’s a lot. Dr. Deb Muth 1:02:08That’s is awesome. David Jernigan 1:02:09Like, if I just said, well, it’s a one in a million chance it was a fluke.Okay.So, lab tests don’t lie. You’re not done, necessarily, just because you got rid of the infections. Now that formula for Lyme has grown to be 90-plusmicrobes targeted in the one formula. So, we figured out we can actually target individually, but collectively, almost like an antibiotic that’s laser-guided to only go after the bad guys that we targeted.So, all the Borrelia types are targeted, all the Babesias, for,the Bartonellas, the anaplasmosis, you name it, mycoplasma types are all targeted in that one formula, because I said.Took my collective 30 years of experience and 15,000 patients.that I would typically see as co-infections and put them into that one formula, so…When we get these tests coming back that are testing for 64, it’s because of that.So, there’s a lot of coolnesses that I could actually keep going and going. Dr. Deb Muth 1:03:15That’s exciting. David Jernigan 1:03:15I love this topic, but I thank you for letting me come on. Dr. Deb Muth 1:03:18Thank you for joining us. How can people find you? David Jernigan 1:03:22Two ways. There’s the Phagen Corp company that is now manufacturing my formulas.That is P-H-A-G-E-N-C-O-R-P dot com. Practitioners can go there, and there’s a practitioner side of the website that’s very beefy with science, and… and all the formulas that were used, what’s inside of all the formulas, meaning what microbes are targeted by each one. Like, there’s a GI formula, there’s a UTI formula, there’s a SIRS formula, there’s a Lyme formula, there’s a central nervous system type infection formula, there’s… And we can keep going, you know, SIBO, SIFO formula, mold formula… I mean, we’ve discovered so many things that I could just keep going for hours, and… Dr. Deb Muth 1:04:05Yeah. David Jernigan 1:04:06About the discoveries, from where it started in its humble beginnings, To now, so… There’s another way, if you wanted to see our clinic website, is Biologics, with an X, so B-I-O-L-O-G-I-X, Center, C-E-N-T-E-R dot com. And, if somebody thinks they want to be a patient and experience this at our clinic, typically we don’t take just Easy stuff. All we see is chronic.Chronic cases from all over the world. Something like 96% of our patients come from other states and countries. And typically, I’ve been close to 90% for my whole career.About 30-something percent come from other countries in that, so… we’ve gotten really good and learned a lot in having to deal with what nobody else knows what to do with. But if you do want to do that, you can contact us. And, if you… If you don’t get the answers from my patient care staff, then I do free consultations. With the people that are thinking about, whether we can help them or not. Dr. Deb Muth 1:05:13Well, that’s excellent. For those of you who are driving or don’t have any way of writing things down, don’t worry about it, we’ve got you. We will have all of his contact information in our show notes, so you will be able to reach out to him. Thank you again for joining me. This has been an amazing conversation. David Jernigan 1:05:30Thank you, I appreciate you having me on. It was a lot of fun. The post Episode 252 – Induced Native Phage Therapy (INPT) & advanced natural therapies first appeared on Let's Talk Wellness Now.

Overview This special episode of the Tick Boot Camp Podcast was recorded live at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and PCOM Symposium in collaboration with Pathobiome Perspectives. Hosted by Ali Moresco in partnership with Nikki Schultek, Executive Director of AlzPI, this series expands the Tick Boot Camp mission of exploring infection-associated chronic illness (IACI)—including Lyme and other tick-borne infections—to the global Alzheimer's and neuroimmunology research community. Tick Boot Camp co-founders Matt Sabatello and Rich Johannesen partnered with Ali and Nikki to showcase scientists exploring the microbial and immune mechanisms behind neurodegeneration. This episode features Dr. Janice Bush, a PhD candidate at North Carolina State University's College of Veterinary Medicine, whose research under world-renowned Bartonella expert Dr. Edward Breitschwerdt investigates how Bartonella bacteria alter gene expression in the brain's immune cells. Guest Janice Bush, DVM, PhD Candidate College of Veterinary Medicine, North Carolina State University (NCSU) Dr. Janice Bush began her career in veterinary medicine, where she observed a striking overlap between illnesses in pets and their human owners—particularly those linked to vector-borne infections like Bartonella. Now completing her PhD under Dr. Edward Breitschwerdt, she focuses on Bartonella henselae, the bacterium behind Cat Scratch Disease, and its ability to infect human microglial cells—the brain's resident immune defenders. Her presentation, “Bartonella-Infected Human Microglial Cells: Transcriptional Changes Associated with Chronic Neurologic Disorders,” revealed how this stealth pathogen triggers widespread gene dysregulation linked to Alzheimer's disease, psychiatric symptoms, and neurodegenerative processes. Key Discussion Points Dr. Bush explains how Bartonella infection reprograms human microglia, the brain's innate immune cells, leading to hundreds of genes being upregulated or suppressed—affecting energy metabolism, mitochondrial function, cell signaling, and immune communication. These cellular changes mirror those observed in chronic neurological and psychiatric disorders, providing a potential mechanistic link between infection and long-term neurodegeneration. She describes Bartonella's sophisticated immune evasion strategy, including its ability to hijack cellular machinery and increase production of interleukin-10 (IL-10)—an anti-inflammatory cytokine that suppresses immune response, allowing the bacteria to persist undetected. This mechanism may explain why patients experience cyclic flares and remissions, and why Bartonella can linger silently for years. Dr. Bush's findings suggest that even short-term infections can produce measurable transcriptional changes in brain immune cells within 48 hours. If such infections persist for months or years, they may set the stage for neurodegenerative disease, particularly when combined with other pathogens or environmental factors. “If one intracellular pathogen can cause this many changes in two days, imagine what happens over months or years. Bartonella may be the spark that primes the brain for neurodegeneration.” — Dr. Janice Bush Why It Matters Dr. Bush's research offers a groundbreaking look at how a common, underrecognized infection may drive neuroinflammation and neurodegeneration. Her work bridges veterinary medicine, infectious disease, and neurology—revealing how pathogens once dismissed as minor or self-limiting may alter the brain's immune landscape. By demonstrating that Bartonella can infect and manipulate microglial cells, she provides critical biological evidence linking vector-borne disease and cognitive decline, paving the way for future diagnostic and therapeutic innovation. About the Event This interview was recorded at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and Philadelphia College of Osteopathic Medicine (PCOM) Symposium, held October 3, 2025, at Ohio University in Dublin, Ohio. The event gathered more than 20 leading researchers exploring how microbes, the microbiome, and immune dysregulation contribute to Alzheimer's, dementia, and infection-associated chronic illness (IACI). The Tick Boot Camp Podcast, in partnership with Ali Moresco and Nikki Schultek, documented these conversations to connect the chronic Lyme, infectious disease, and Alzheimer's research communities. This episode is part of Tick Boot Camp's AlzPI collaboration series. Learn More Learn more about the Alzheimer's Pathobiome Initiative (AlzPI) Listen to Tick Boot Camp Podcast episodes, including Episode 406: Pathobiome – An Interview with Nikki Schultek and Episode 101: The Young Gun – An Interview with Alex (Ali) Moresco discussed in this interview.

View the Show Notes For This Episode Dr. Neil Nathan discusses Mold Toxicity, Lyme Disease, and Environmental Toxins with Dr. Ben Weitz.   [If you enjoy this podcast, please give us a rating and review on Apple Podcasts, so more people will find The Rational Wellness Podcast. Also check out the video version on my WeitzChiro YouTube page.]  Podcast Highlights Understanding and Treating Complex Chronic Illnesses with Dr. Neil Nathan   In this episode of the Rational Wellness Podcast, host Dr. Ben Weitz interviews Dr. Neil Nathan, an expert in treating complex chronic illnesses such as mold toxicity, Lyme disease, mast cell activation syndrome, and multiple chemical sensitivities. Dr. Nathan shares insights from his 50-year career, including how to identify these conditions through specific symptoms and the importance of environment assessment. They discuss effective testing methods, treatment approaches, and managing coexisting conditions. The conversation also covers the role of mold in these chronic illnesses and underlines the necessity of personalized treatment plans. Dr. Nathan also touches on the significance of limbic and vagal nerve treatments and shares his experience with various diagnostic and therapeutic tools.   00:00 Introduction to the Rational Wellness Podcast 00:29 Meet Dr. Neil Nathan: Pioneer in Treating Complex Chronic Illnesses 02:02 Understanding Mold Toxicity and Lyme Disease 05:58 Testing for Mold and Lyme: Effective Methods and Challenges 18:26 Mast Cell Activation Syndrome: Symptoms and Diagnosis 21:31 Approach to Treating Complex Patients 28:16 Mold Treatment Protocols and Environmental Considerations 31:25 Understanding Mycotoxin Binders 32:00 Antifungal Treatments for Mold Colonization 32:22 Detoxification Strategies and Patient Sensitivity 35:00 Combination Binders and Patient Sensitivity 39:45 Probiotics and Antibiotics for Lyme and Bartonella 45:42 Mast Cell Activation Syndrome and Limbic System Reboot 51:50 Common Mistakes in Treating Chronic Illness 58:01 Final Thoughts and Resources     Dr. Neil Nathan is a Medical Doctor who is a pioneer in the treatment of complex chronic illnesses including mold toxicity, Lyme disease, mast cell activation syndrome, multiple chemical sensitivities, and other environmental illnesses. Dr. Nathan has spent 50 years treating some of the most sensitive and complex patients recover their health and studying and learning and teaching how to treat such patients. He has written a number of books, including On Hope and Healing, Healing is Possible, Mold and Mycotoxins: Current Evaluation and Treatment 2016 (just updated, as an e-book, Mold and Mycotoxins 2022), Toxic 2nd edition: Heal Your Body from Mold Toxicity, Lyme Disease, Multiple Chemical Sensitivities and Chronic Environmental Illness, Energetic Diagnosis, and The Sensitive Patient's Healing Guide.  His website is NeilNathanMD.com. Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure.  Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.  

Overview This special episode of the Tick Boot Camp Podcast was recorded live at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and PCOM Symposium in collaboration with Pathobiome Perspectives. Hosted by Ali Moresco in partnership with Nikki Schultek (Executive Director, AlzPI), the conversation advances the Tick Boot Camp mission of exploring infection-associated chronic illness (IACI)—including Lyme disease and other tick-borne infections—within the global Alzheimer's and neuroimmunology community. Tick Boot Camp co-founders Matt Sabatello and Rich Johannesen partnered with Ali and Nikki to amplify voices connecting tick-borne illness, microbes, and cognitive decline. This episode features Nicole Bell—author, entrepreneur, and CEO of Galaxy Diagnostics—whose memoir What Lurks in the Woods documents her late husband Russ's misdiagnosed tick-borne illness and their search for answers. Guest Nicole Bell Author of What Lurks in the Woods CEO, Galaxy Diagnostics Advocate for tick-borne and neurodegenerative disease BS/MS, Materials Science & Engineering (MIT) MS, Biomedical Engineering (Duke University) At the Symposium, Nicole presented “When the brain pathobiome becomes personal,” sharing her family's journey and new findings from Russ's donated brain: laboratory evidence of Borrelia burgdorferi, Chlamydia pneumoniae, and Babesia otocoli (a species long thought to be deer-restricted) in brain tissue—data now being prepared for publication. Researchers also noted elevated heavy metals (lead, mercury), underscoring how polymicrobial infection plus toxic exposures may converge to drive neuroinflammation and Alzheimer's-like decline. Key Discussion Points Nicole details how repeated “normal” neurology workups masked a complex pathobiome process. She explains why standard two-tier Lyme serology can miss true infection, how direct detection can change care, and why patients should consider Bartonella and Babesia alongside Lyme. She outlines hallmark Bartonella clues—including striæ that resemble stretch marks (often more visible after hot showers), neuropsychiatric manifestations (irritability, anxiety, OCD, tics), ocular and joint involvement—and highlights non-tick vectors (notably fleas and household cats) that expand risk beyond forest exposure. Nicole advocates for building a diagnostic toolkit that combines serology with sensitive direct tests to clarify which pathogens are active—critical because Borrelia, Bartonella, and Babesia require different treatment paradigms. Looking forward, she envisions comprehensive screening panels for midlife cognitive changes that integrate pathogen load, host immune signatures, and toxin status, enabling earlier, targeted interventions. “Everyone wants a simple A→B. But the toughest chronic conditions are subtle and multifactorial. Accurate data, direct detection, and a clinician who will go on the journey with you can change everything.” — Nicole Bell Why It Matters Nicole's story humanizes the science: polymicrobial infection + toxins + host factors can look “psychiatric” or “idiopathic” until modern testing reveals the underlying pathobiome. Her advocacy pushes medicine toward precision diagnostics, earlier detection, and pathogen-informed care that may prevent years of decline. About the Event Recorded at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and Philadelphia College of Osteopathic Medicine (PCOM) Symposium on October 3, 2025, at Ohio University (Dublin, Ohio). The meeting convened global experts investigating how microbes, the microbiome, and immune responses contribute to Alzheimer's, dementia, PANS/PANDAS, and other infection-associated chronic illnesses (IACI). This episode is part of a Tick Boot Camp series connecting chronic Lyme research with cutting-edge brain-immune science. Learn More Learn more about the Alzheimer's Pathobiome Initiative (AlzPI) Listen to Tick Boot Camp Podcast episodes, including Episode 406: Pathobiome – An Interview with Nikki Schultek, Episode 101: The Young Gun – An Interview with Alex (Ali) Moresco, and Episode 216: What Lurks in the Woods – an interview with Nicole Bell discussed in this interview.

In this episode of Integrative Lyme Solutions with Dr. Karlfeldt, Dr. Michael Karlfeldt is joined by Dr. Steven Harris, an expert in Lyme disease. They discuss the complexities of diagnosing and treating Lyme disease, co-infections, and the significance of understanding the immune response. Dr. Harris shares insights into advanced diagnostic testing, including immuno blot, PCR, and T-cell testing. He also explains the importance of clinical diagnosis in Lyme disease and the roles of various co-infections such as Babesia, Bartonella, and Anaplasma. The episode provides an in-depth look at how modern technology and methodologies are improving the accuracy and effectiveness of Lyme disease treatment. 04:15 Current State of Lyme Testing 10:47 Advanced Testing Techniques 18:03 Strategies for Accurate Diagnosis 25:40 Frustrations and Rewards in Lyme Treatment 35:50 T-Cell Testing and Its Benefits 43:16 Co-Infections and Their Symptoms 47:57 Conclusion and Final Thoughts --------------- The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email info@TheKarlfeldtCenter.com Check out Dr. K's Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lyme You can purchase it for $24.99 or use the code LYMEPODCAST for a 100% off discount! _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email info@TheKarlfeldtCenter.comCheck out Dr. K's Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

In this episode of Integrative Lyme Solutions with Dr. Michael Karlfeldt, law enforcement veteran Janice Niederhofer shares her harrowing journey battling Bartonella and Lyme disease. From her initial symptoms to years of misdiagnosis, Janice discusses the mental and physical toll these invisible illnesses took on her life and career. She emphasizes the importance of finding expert care, being compliant with treatments, and maintaining a positive outlook. This inspiring conversation sheds light on the challenges faced by Lyme disease sufferers and offers hope through persistence and support. 05:36 The Turning Point: A Flea Bite and Mysterious Symptoms 08:38 Struggles with Misdiagnosis and Financial Hardships 16:04 Isolation and Finding a Reason to Live 18:56 A Ray of Hope: Meeting the Right Doctor 26:39 Personal Journey and Overcoming Challenges 37:55 Finding New Identity and Purpose ------------ The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email info@TheKarlfeldtCenter.com Check out Dr. K's Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeYou can purchase it for $24.99 or use the code LYMEPODCAST for a 100% off discount! _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email info@TheKarlfeldtCenter.comCheck out Dr. K's Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

Overview This special episode of the Tick Boot Camp Podcast was recorded live at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and PCOM Symposium in collaboration with Pathobiome Perspectives. Hosted by Ali Moresco in partnership with Nikki Schultek, Executive Director of AlzPI, the conversation brings the Tick Boot Camp mission of exploring infection-associated chronic illness (IACI), like Lyme disease and other tick-borne diseases, to the global Alzheimer's and neuroimmunology research community. Tick Boot Camp co-founders Matt Sabatello and Rich Johannesen partnered with Ali and Nikki to highlight scientists whose work connects tick-borne illness, microbes, and cognitive decline. This episode features Dr. Brian J. Balin, an internationally recognized neuroscientist whose research has redefined the role of infection in contributing to Alzheimer's disease. Guest Brian J. Balin, PhD Professor of Neuroscience and Neuropathology Director, Center for Chronic Disorders of Aging Philadelphia College of Osteopathic Medicine (PCOM) Dr. Balin directs the Center for Chronic Disorders of Aging and the Adolph and Rose Levis Foundation Laboratory for Alzheimer's Disease Research at PCOM. With a PhD from the University of Maryland School of Medicine and postdoctoral training at the University of Pennsylvania, he has devoted nearly three decades to understanding how chronic infection and inflammation trigger neurodegeneration. His pioneering discovery that the respiratory bacterium Chlamydia pneumoniae infects brain tissue helped establish the Pathogen Hypothesis of Alzheimer's disease. His continuing work explores how tick-borne microbes — including Borrelia burgdorferi (Lyme disease), Bartonella, and Babesia — interact with other pathogens to drive neuroinflammation and cognitive decline. Key Discussion Points How infections such as Chlamydia pneumoniae, Borrelia burgdorferi, Bartonella, and Babesia were detected in Alzheimer's brain tissue. Evidence that microbes can enter the brain via the olfactory pathway or blood-brain barrier, initiating chronic inflammation, amyloid plaque formation, and tau tangle pathology. Findings from Dr. Balin's collaboration with Galaxy Diagnostics and advocate Nicole Bell, revealing polymicrobial infection and even Babesia otocoli — a strain previously believed to infect only deer — in human brain tissue. The use of animal models and 3D human brain organoids to study infection-driven neurodegeneration. Why identifying infection as part of the exposome (environmental insults over a lifetime) is key to developing precision diagnostics and treatments. Future directions: immune-modulating drugs, antimicrobials, and emerging phage therapy. “Infection is part of the exposome — an environmental insult that shapes our health over a lifetime. Recognizing that is key to truly understanding and preventing Alzheimer's disease.” — Dr. Brian J. Balin Why It Matters Dr. Balin's research bridges the worlds of neurology and infectious disease, offering a framework that could revolutionize how Alzheimer's and other neurodegenerative conditions are diagnosed and treated. By recognizing that microbes — including those transmitted by ticks — can initiate neuroinflammation and cognitive decline, his work provides hope for millions living with infection-associated chronic illness. About the Event The interview took place at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and Philadelphia College of Osteopathic Medicine (PCOM) Symposium, October 3, 2025, Ohio University in Dublin, Ohio. The Symposium brought together more than 20 experts exploring how microbes, the microbiome, and the host immune response contribute to neurological and psychiatric diseases such as Alzheimer's, dementia, and PANS/PANDAS. Tick Boot Camp partnered with Ali Moresco and Nikki Schultek to document and share the voices of scientists advancing research on infection-associated chronic illness (IACI). This episode is part of a special series showcasing how pathobiome and microbiome science is changing our understanding of chronic Lyme and neurodegenerative disease. Learn More Learn about the Alzheimer's Pathobiome Initiative (AlzPI) at AlzPI.org. For Dr. Balin's publications and ongoing research, visit the Philadelphia College of Osteopathic Medicine (PCOM) website. Learn more about the Alzheimer's Pathobiome Initiative (AlzPI) Listen to Tick Boot Camp Podcast episodes, including Episode 406: Pathobiome – An Interview with Nikki Schultek and Episode 101: The Young Gun – An Interview with Alex (Ali) Moresco discussed in this interview.

In this powerful episode of the Tick Boot Camp Podcast, international DJ and artist duo Z3LLA — Julia “Juj” Seeley and Kiana Tebyani — share how chronic illness, creativity, and friendship became the foundation of their success. After years of unexplained symptoms, Juj was diagnosed with Lyme disease, Bartonella, Babesia, mold toxicity, POTS, SIBO, celiac disease, and later catamenial epilepsy. Despite life-altering health challenges, she and her best friend Kiana have built Z3LLA into one of the most exciting names in house music — with their single “Why Should I?” reaching #1 on the US Dance Radio Charts and performances alongside Disco Lines, Galantis, and Bijou. Together, Juj and Kiana discuss performing through flare-ups, collapsing backstage, navigating the medical system, and the emotional toll of chasing dreams while managing invisible illness. From ER visits and red-light therapy to steroid crashes and spiritual breakthroughs, this episode is a masterclass in resilience, vulnerability, and using art as advocacy.

Recorded in person in Central Park, NYC just before Project Lab Coat at New York Fashion Week (NYFW), this Tick Boot Camp Podcast features Dr. Bill Rawls on what helps chronic Lyme patients move from overwhelm to progress. We talk immune-first strategy, why antibiotics often fall short in chronic cases, how to protect the gut, and a stepwise plan that reduces flare risk and builds confidence. Episode snapshot Dr. Rawls explains why stealth microbes like Borrelia, Bartonella, and Babesia grow slowly and hide in tissues, which is why a quick-fix antibiotic approach often disappoints in chronic illness. We discuss a four-phase healing framework — prehabilitation, assist the immune system, rehabilitation, and maintenance (PARM) — and how a gradual, system-calming on-ramp helps patients tolerate protocols without crashing. We also dig into gut protection, community support, and how AI can speed education and research. What you will learn Why “assist the immune system” beats “kill at all costs” for chronic Lyme Stealth microbe biology and why slow growth changes the treatment playbook Antibiotic overuse risks including microbiome injury and antibiotic resistance Gut and detox support as foundations for energy, sleep, and resilience A stepwise entry to treatment that reduces flares and anxiety Key herbs with evidence for tick-borne infections and immune modulation Community and education as levers for consistency and long-term success How AI tools can accelerate research, writing, and practical guidance Key topics and takeaways Four phases of recovery: prehab, assist, rehab, maintenance Antibiotics in chronic Lyme: may disrupt the gut before meaningfully impacting slow-growing pathogens Herbal strategy: sustained pressure over time with immune support Gradual on-ramp: calm the nervous system first, then gut and detox, then stronger antimicrobials Team sport: combine self-care, educated use of providers, and moderated community support Herbs and supports mentioned Antimicrobial herbs: Japanese knotweed, Chinese skullcap, Cryptolepis, cat's claw, garlic Immune-modulating adaptogens: reishi, cordyceps Supportive nutrients: B vitamins, minerals, NAC, glutathione Formats: capsules and tinctures were discussed, including products like Advanced Biotic and Biome Boost within larger protocols Patient-friendly pacing Months 1–2: calm sympathetic overdrive, improve sleep, stabilize Months 3–4: protect gut, support detox, keep gentle antimicrobial pressure Months 5–6: advance to stronger combinations when the body is ready Ongoing: measure progress, maintain gain, prevent backsliding Notable quotes “The immune system always wins the game. Your job is to assist it.” “Stealth microbes grow slowly and hide in tissues. The strategy has to match the biology.” “Education and a supportive community reduce fear and make consistency possible.” Resources and links Watch the video version of this podcast interview on YouTube Read our NYFW Recap: Tick Boot Camp models at Project Labcoat and Why it Matters for Lyme Awareness, Research, and Funding

Why You Should Listen:  In this episode, you will learn about the latest approaches to healing your body from mold toxicity, Lyme disease, and other complex, chronic health conditions. About My Guest: My guest for this episode is Dr. Neil Nathan.  Neil Nathan, MD has been practicing medicine for over 50 years and has been Board Certified in Family Practice and Pain Management and is a Founding Diplomate of the American Board of Integrative Holistic Medicine and a Founding Diplomate of ISEAI. He has written several books, including "Healing is Possible: New Hope for Chronic Fatigue, Fibromyalgia, Persistent Pain, and Other Chronic Illnesses" and "On Hope and Healing: For Those Who Have Fallen Through the Medical Cracks."  He has been working to bring an awareness that mold toxicity is a major contributing factor for patients with chronic illness and lectures internationally on this subject which led to the publication of his eBook, "Mold and Mycotoxins: Current Evaluation and Treatment, 2016" (now updated to 2022), and then to his best-selling book "Toxic: Heal Your Body from Mold Toxicity, Lyme Disease, Multiple Chemical Sensitivities and Chronic Environmental Illness."  2021 saw the publication of "Energetic Diagnosis," a discussion of the value of intuition and energetic devices as an aid to both diagnosis and treatment of medical illness.  In 2024, his book "The Sensitive Patient's Healing Guide" was released with a focus on how to approach the treatment of sensitive patients.  And most recently, in late 2025, the second edition of his book "Toxic" was released with several years of new information and insights on healing from complex chronic conditions.  Dr. Nathan has been treating chronic complex medical illnesses for 30 years now, and Lyme disease for the past 20 years.  As his practice has evolved, he finds himself increasingly treating the patients who have become so sensitive and toxic that they can no longer tolerate their usual treatments, and his major current interest is in finding unique ways of helping them to recover. Key Takeaways: Is Long COVID the Great Unmasker? Is POTS an underlying cause or is it a symptom? How might the Radiance Long Hauler testing be helpful? What supplements or botanicals may be helpful for those in a Cell Danger Response? Are hormones generally well-tolerated when one is in a Cell Danger Response? When might be the right time to introduce PC?  VIP? What are the more common sensitizers of a sensitive patient? What are the more common drivers of MCAS? What are some strategies for modulating the inflammatory response? Is MCS the same as MCAS? Should limbic retraining be more active? How often are mycotoxins seen in patients with Alzheimer's? Does HLA-DR impact a patient's recovery potential? How do you handle a suspected mold illness patient when their urine mycotoxin testing is negative? What is the best binder for mycophenolic acid?  Chaetoglobosin? Do the benefits of bentonite clay outweigh the potential risks? What is the source of gliotoxin in the body? How is the treatment of fungal colonization approached? What role have Actinobacteria and endotoxins played in treating patients? Can Bartonella be treated with natural antimicrobials alone? Does treating mold and Lyme improve EDS? Can secondary porphyria be an indication that the antimicrobial is working? What is the role of EMFs in chronic illness? How large of a factor are parasites? Do mold and Lyme contribute to ME/CFS, Fibromyalgia, autism, and PANS/PANDAS? What is the role of nitric oxide in recovering health? Connect With My Guest:  NeilNathanMD.com Related Resources: Toxic 2nd Edition: Heal Your Body from Mold Toxicity, Lyme Disease, Multiple Chemical Sensitivities, and Chronic Environmental Illness Interview Date: September 29, 2025 Transcript: To review a transcript of this show, visit https://BetterHealthGuy.com/Episode223. Support the Show: To support the show and Buy Me a Coffee, visit https://betterhealthguy.link/BuyMeACoffee. Additional Information: To learn more, visit https://BetterHealthGuy.com. Follow Me on Social Media: Facebook - https://facebook.com/betterhealthguy Instagram - https://instagram.com/betterhealthguy X - https://twitter.com/betterhealthguy TikTok - https://tiktok.com/@betterhealthguy Disclaimer:  The content of this show is for informational purposes only and is not intended to diagnose, treat, or cure any illness or medical condition. Nothing in today's discussion is meant to serve as medical advice or as information to facilitate self-treatment. As always, please discuss any potential health-related decisions with your own personal medical authority. 

Millions of people are living with unexplained symptoms like allergies, brain fog, anxiety, and chronic fatigue without realizing the hidden cause: mast cells gone rogue. In this episode of The Human Upgrade, Host Dave Asprey sits down with leading functional medicine physician Dr. Tania Dempsey to uncover how Mast Cell Activation Syndrome (MCAS) drives inflammation, disrupts mitochondria, and sabotages metabolism—and what you can do to switch it off. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Dr. Dempsey is internationally recognized for her work in functional medicine, biohacking, and chronic illness. She co-founded the AIM Center for Personalized Medicine, has published groundbreaking research on MCAS with Dr. Lawrence Afrin, and treats some of the most complex cases of immune dysregulation, autoimmune disease, and environmental illness. Her expertise helps you understand why mast cells are the missing link in allergies, long COVID, Lyme, mold toxicity, and even hormone disruption—and how to reclaim control of your biology. Dave and Dr. Dempsey break down how mast cells interact with mitochondria, hormones, and the nervous system, showing how chronic inflammation accelerates aging and blocks human performance. You'll discover why biohacking tools like fasting, ketosis, supplements, red light, cold therapy, sleep optimization, and smarter not harder lifestyle strategies all influence mast cell stability. They also explore why brain optimization, neuroplasticity, and nootropics are essential for calming inflammatory cascades, and how functional medicine provides practical solutions beyond conventional treatment. You'll Learn: • Why mast cells are the hidden switch behind allergies, chronic inflammation, and brain fog • How mitochondria and mast cells work together to drive human performance—or disease • The connection between toxic mold, Lyme, long COVID, hormone imbalance, and MCAS • How supplements, fasting, ketosis, and cold therapy stabilize mast cells and boost longevity • Why functional medicine and biohacking are essential for complex chronic illness • How mast cells impact metabolism, sleep optimization, and neuroplasticity • The surprising link between mast cells, anxiety, and mental health symptoms This episode is essential for anyone serious about hacking inflammation, protecting longevity, upgrading metabolism, and achieving high performance with resilience and clarity. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: mast cell activation syndrome, MCAS, chronic inflammation, mitochondria dysfunction, histamine intolerance, functional medicine, biohacking, allergies, brain fog, long covid, mold toxicity, Bartonella, Lyme co-infections, oxalates, salicylates, mast cell stabilizers, immune dysregulation, neuroinflammation, chronic fatigue syndrome, autoimmune triggers, personalized medicine, longevity supplements Thank you to our sponsors!Leela Quantum Tech | Head to https://leelaq.com/DAVE for 10% off.LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/DAVE.Resources: • Tania's Website: https://drtaniadempsey.com/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 — Trailer 01:10 — Introduction 03:27 — Why So Sick Today? 05:57 — MCAS Explained 08:33 — Mold & Environment 11:36 — Spotting MCAS 13:43 — Personal Stories 15:15 — Research & Biohacking 16:35 — Managing Triggers 20:15 — Gut & Stomach Acid 22:42 — Reaction Timing 25:30 — Hormones & MCAS 28:39 — Thyroid & Mitochondria 32:28 — Chronic Illness Navigation 40:06 — Insurance Battles 44:44 — Cholesterol & Ethics 49:11 — Personalized Care 53:24 — Circadian & Stress 58:24 — Testing Approaches 01:01:35 — Collagen & Joints 01:04:34 — MMPs & Aging 01:09:12 — Access & Experimentation 01:13:14 — MCAS & Mental Health 01:17:46 — Benzos & Stigma 01:20:23 — Vaccines & Spike Protein 01:25:18 — Research & Treatments 01:26:12 — Nicotine & Focus 01:29:24 — Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.