Podcasts about icaac

Drs. Tom Dilworth and Stephanie Shealy May (@stephshealymay) join Dr. Rachel Britt (@RachelBPharmD) in the first episode of Breakpoints Dosing Consults to discuss questions and debates around ceftriaxone dosing. When should we use 1g over 2g? How does critical illness affect what dose to use? Is ceftriaxone the most approachable antibiotic? Tune in for answers to these questions and more!   Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm (https://twitter.com/SIDPharm) Instagram: @SIDPharm (https://www.instagram.com/sidpharm/) Facebook: https://www.facebook.com/sidprx LinkedIn: https://www.linkedin.com/company/sidp/ References Ettestad PJ, Campbell GL, Welbel SF, Genese CA, Spitalny KC, Marchetti CM, Dennis DT. Biliary complications in the treatment of unsubstantiated Lyme disease. J Infect Dis. 1995 Feb;171(2):356-61. doi: 10.1093/infdis/171.2.356. PMID: 7844372. Hasegawa S, Sada R, Yaegashi M, Morimoto K, Mori T; Adult Pneumonia Study Group-Japan. 1g versus 2 g daily intravenous ceftriaxone in the treatment of community onset pneumonia - a propensity score analysis of data from a Japanese multicenter registry. BMC Infect Dis. 2019 Dec 26;19(1):1079. doi: 10.1186/s12879-019-4552-8. PMID: 31878894; PMCID: PMC6933656. Barber KE, Loper JT, Morrison AR, Stover KR, Wagner JL. Impact of Obesity on Ceftriaxone Efficacy. Diseases. 2020 Jul 9;8(3):27. doi: 10.3390/diseases8030027. PMID: 32660113; PMCID: PMC7563366. Herrera-Hidalgo L, de Alarcón A, López-Cortes LE, Luque-Márquez R, López-Cortes LF, Gutiérrez-Valencia A, Gil-Navarro MV. Is Once-Daily High-Dose Ceftriaxone plus Ampicillin an Alternative for Enterococcus faecalis Infective Endocarditis in Outpatient Parenteral Antibiotic Therapy Programs? Antimicrob Agents Chemother. 2020 Dec 16;65(1):e02099-20. doi: 10.1128/AAC.02099-20. Erratum in: Antimicrob Agents Chemother. 2021 May 18;65(6): PMID: 33046488; PMCID: PMC7927845. Herrera-Hidalgo L, Lomas-Cabezas JM, López-Cortés LE, Luque-Márquez R, López-Cortés LF, Martínez-Marcos FJ, de la Torre-Lima J, Plata-Ciézar A, Hidalgo-Tenorio C, García-López MV, Vinuesa D, Gutiérrez-Valencia A, Gil-Navarro MV, De Alarcón A. Ampicillin Plus Ceftriaxone Combined Therapy for Enterococcus faecalis Infective Endocarditis in OPAT. J Clin Med. 2021 Dec 21;11(1):7. doi: 10.3390/jcm11010007. PMID: 35011748; PMCID: PMC8745305. Workowski KA, Bachmann LH, Chan PA, Johnston CM, Muzny CA, Park I, Reno H, Zenilman JM, Bolan GA. Sexually Transmitted Infections Treatment Guidelines, 2021. MMWR Recomm Rep. 2021 Jul 23;70(4):1-187. doi: 10.15585/mmwr.rr7004a1. PMID: 34292926; PMCID: PMC8344968. Whittles LK, White PJ, Paul J, Didelot X. Epidemiological Trends of Antibiotic Resistant Gonorrhoea in the United Kingdom. Antibiotics (Basel). 2018 Jul 13;7(3):60. doi: 10.3390/antibiotics7030060. PMID: 30011825; PMCID: PMC6165062. Ackerman A, Zook NR, Siegrist JF, Brummitt CF, Cook MM, Dilworth TJ. Comparison of Clinical Outcomes among Intensive Care Unit Patients Receiving One or Two Grams of Ceftriaxone Daily. Antimicrob Agents Chemother. 2020 May 21;64(6):e00066-20. doi: 10.1128/AAC.00066-20. PMID: 32205348; PMCID: PMC7269488. Ulldemolins M, Roberts JA, Rello J, Paterson DL, Lipman J. The effects of hypoalbuminaemia on optimizing antibacterial dosing in critically ill patients. Clin Pharmacokinet. 2011 Feb;50(2):99-110. doi: 10.2165/11539220-000000000-00000. PMID: 21142293. Dailly E, Arnould JF, Fraissinet F, Naux E, Letard de la Bouralière MA, Bouquié R, Deslandes G, Jolliet P, Le Floch R. Pharmacokinetics of ertapenem in burns patients. Int J Antimicrob Agents. 2013 Jul;42(1):48-52. doi: 10.1016/j.ijantimicag.2013.02.021. Epub 2013 Apr 8. PMID: 23578794. Pai MP. Treatment of bacterial infections in obese adult patients: how to appropriately manage antimicrobial dosage. Curr Opin Pharmacol. 2015 Oct;24:12-7. doi: 10.1016/j.coph.2015.06.004. Epub 2015 Jun 25. PMID: 26119488. Mahmood I. Theoretical versus empirical allometry: Facts behind theories and application to pharmacokinetics. J Pharm Sci. 2010 Jul;99(7):2927-33. doi: 10.1002/jps.22073. PMID: 20127826. Kang N, Housman ST, Nicolau DP. Assessing the Surrogate Susceptibility of Oxacillin and Cefoxitin for Commonly Utilized Parenteral Agents against Methicillin-Susceptible Staphylococcus aureus: Focus on Ceftriaxone Discordance between Predictive Susceptibility and in Vivo Exposures. Pathogens. 2015 Jul 30;4(3):599-605. doi: 10.3390/pathogens4030599. PMID: 26264030; PMCID: PMC4584275. Gern BH, Greninger AL, Weissman SJ, Stapp JR, Tao Y, Qin X. Continued in vitro cefazolin susceptibility in methicillin-susceptible Staphylococcus aureus. Ann Clin Microbiol Antimicrob. 2018 Feb 20;17(1):5. doi: 10.1186/s12941-018-0257-x. PMID: 29463249; PMCID: PMC5819674. Bremmer DN, Balada-Llasat JM, Goff DA, Bauer KA. Ceftriaxone Etest non-susceptible methicillin susceptible Staphylococcus aureus time-kill responses. Diagn Microbiol Infect Dis. 2017 Jun;88(2):192-194. doi: 10.1016/j.diagmicrobio.2017.02.019. Epub 2017 Mar 2. PMID: 28291629. Kosowska-Shick K, McGhee PL, Appelbaum PC. Affinity of ceftaroline and other beta-lactams for penicillin-binding proteins from Staphylococcus aureus and Streptococcus pneumoniae. Antimicrob Agents Chemother. 2010 May;54(5):1670-7. doi: 10.1128/AAC.00019-10. Epub 2010 Mar 1. PMID: 20194704; PMCID: PMC2863635. Palmer SM, Kang SL, Cappelletty DM, Rybak MJ. Bactericidal killing activities of cefepime, ceftazidime, cefotaxime, and ceftriaxone against Staphylococcus aureus and beta-lactamase-producing strains of Enterobacter aerogenes and Klebsiella pneumoniae in an in vitro infection model. Antimicrob Agents Chemother. 1995 Aug;39(8):1764-71. doi: 10.1128/AAC.39.8.1764. PMID: 7486916; PMCID: PMC162823. Craig WA. Interrelationship between pharmacokinetics and pharmacodynamics in determining dosage regimens for broad-spectrum cephalosporins. Diagn Microbiol Infect Dis. 1995 May-Jun;22(1-2):89-96. doi: 10.1016/0732-8893(95)00053-d. PMID: 7587056. Garot D, Respaud R, Lanotte P, Simon N, Mercier E, Ehrmann S, Perrotin D, Dequin PF, Le Guellec C. Population pharmacokinetics of ceftriaxone in critically ill septic patients: a reappraisal. Br J Clin Pharmacol. 2011 Nov;72(5):758-67. doi: 10.1111/j.1365-2125.2011.04005.x. PMID: 21545483; PMCID: PMC3243010. Joynt GM, Lipman J, Gomersall CD, Young RJ, Wong EL, Gin T. The pharmacokinetics of once-daily dosing of ceftriaxone in critically ill patients. J Antimicrob Chemother. 2001 Apr;47(4):421-9. doi: 10.1093/jac/47.4.421. PMID: 11266414. Van Wart SA et al., ICAAC 2009, poster # A1-010 Housman ST, Sutherland CA, Nicolau DP. Pharmacodynamic profile of commonly utilised parenteral therapies against meticillin-susceptible and meticillin-resistant Staphylococcus aureus collected from US hospitals. Int J Antimicrob Agents. 2014 Sep;44(3):235-41. doi: 10.1016/j.ijantimicag.2014.05.012. Epub 2014 Jun 24. PMID: 25052866. Zelenitsky SA, Beahm NP, Iacovides H, Ariano RE, Zhanel G. Limitations of ceftriaxone compared with cefazolin against MSSA: an integrated pharmacodynamic analysis. J Antimicrob Chemother. 2018 Jul 1;73(7):1888-1894. doi: 10.1093/jac/dky120. PMID: 29635472. Paul M, Zemer-Wassercug N, Talker O, Lishtzinsky Y, Lev B, Samra Z, Leibovici L, Bishara J. Are all beta-lactams similarly effective in the treatment of methicillin-sensitive Staphylococcus aureus bacteraemia? Clin Microbiol Infect. 2011 Oct;17(10):1581-6. doi: 10.1111/j.1469-0691.2010.03425.x. Epub 2010 Dec 14. PMID: 21073629. Carr DR, Stiefel U, Bonomo RA, Burant CJ, Sims SV. A Comparison of Cefazolin Versus Ceftriaxone for the Treatment of Methicillin-Susceptible Staphylococcus aureus Bacteremia in a Tertiary Care VA Medical Center. Open Forum Infect Dis. 2018 May 18;5(5):ofy089. doi: 10.1093/ofid/ofy089. PMID: 30568987; PMCID: PMC5961173. Check out our podcast host, Pinecast. Start your own podcast for free with no credit card required. If you decide to upgrade, use coupon code r-7e7a98 for 40% off for 4 months, and support Breakpoints.

Vincent, Elio, and Michael explore the fossilization of archaeal lipids, and highlight the recent ICAAC in Washington, D.C.  

Vincent and Michael recorded this episode at the 53rd ICAAC in Denver, where they spoke with James Gern and James Johnson about rhinoviruses and extra-intestinal pathogenic E. coli. Links for this Episode: Virus/allergen interactions in asthma (Curr Allerg Asth Rep) Features of rhinovirus C (Microbes Infect) Multidrug resistant ExPec in animals and food (Vet Micro) STS131 an emerging pathogen among veterans (Clin Inf Dis) Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss atmicrobeworld.org and tag them with twim.

Vincent and Michael recorded this episode at the 53rd ICAAC in Denver, where they spoke with James Gern and James Johnson about rhinoviruses and extra-intestinal pathogenic E. coli. Links for this Episode: Virus/allergen interactions in asthma (Curr Allerg Asth Rep) Features of rhinovirus C (Microbes Infect) Multidrug resistant ExPec in animals and food (Vet Micro) STS131 an emerging pathogen among veterans (Clin Inf Dis) Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss atmicrobeworld.org and tag them with twim.

Vincent and Michael recorded this episode at the 53rd ICAAC in Denver, where they spoke with James Gern and James Johnson about rhinoviruses and extra-intestinal pathogenic E. coli.

Vincent and Michael recorded this episode at the 53rd ICAAC in Denver, where they spoke with James Gern and James Johnson about rhinoviruses and extra-intestinal pathogenic E. coli. Links for this Episode: Virus/allergen interactions in asthma (Curr Allerg Asth Rep) Features of rhinovirus C (Microbes Infect) Multidrug resistant ExPec in animals and food (Vet Micro) STS131 an emerging pathogen among veterans (Clin Inf Dis) Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss atmicrobeworld.org and tag them with twim.

Hosts: Vincent Racaniello and Robert Garcea Vincent and Robert recorded this episode at the 53rd ICAAC in Denver, where they talked about polyomaviruses. Links for this episode: A cornucopia of human polyomaviruses (Nat Rev Micro)Polyoma assembly factories in nucleus (PLoS Path)Overprinting gene in Merkel cell polyomavirus (PNAS)Human JCV as population marker (PLoS One)Letters read on TWiV 250Weekly Science Picks Robert - The Panic Virus by Seth MnookinVincent - Aliens chestburster behind the scenes Listener Pick of the Week Adam - Virology Fact of the DayChristophe - dr Karl Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello and Robert Garcea Vincent and Robert recorded this episode at the 53rd ICAAC in Denver, where they talked about polyomaviruses. Links for this episode: A cornucopia of human polyomaviruses (Nat Rev Micro)Polyoma assembly factories in nucleus (PLoS Path)Overprinting gene in Merkel cell polyomavirus (PNAS)Human JCV as population marker (PLoS One)Letters read on TWiV 250Weekly Science Picks Robert - The Panic Virus by Seth MnookinVincent - Aliens chestburster behind the scenes Listener Pick of the Week Adam - Virology Fact of the DayChristophe - dr Karl Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello and Robert Garcea Vincent and Robert recorded this episode at the 53rd ICAAC in Denver, where they talked about polyomaviruses. Links for this episode: A cornucopia of human polyomaviruses (Nat Rev Micro) Polyoma assembly factories in nucleus (PLoS Path) Overprinting gene in Merkel cell polyomavirus (PNAS) Human JCV as population marker (PLoS One) Letters read on TWiV 250 Video of this episode (YouTube) Weekly Science Picks Robert - The Panic Virus by Seth MnookinVincent - Aliens chestburster behind the scenes Listener Pick of the Week Adam - Virology Fact of the DayChristophe - dr Karl Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello and Robert Garcea Vincent and Robert recorded this episode at the 53rd ICAAC in Denver, where they talked about polyomaviruses. Links for this episode: A cornucopia of human polyomaviruses (Nat Rev Micro)Polyoma assembly factories in nucleus (PLoS Path)Overprinting gene in Merkel cell polyomavirus (PNAS)Human JCV as population marker (PLoS One)Letters read on TWiV 250Weekly Science Picks Robert - The Panic Virus by Seth MnookinVincent - Aliens chestburster behind the scenes Listener Pick of the Week Adam - Virology Fact of the DayChristophe - dr Karl Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Vincent, Michael, Elio, and Joe review highlights of the 15th International Symposium on Staphylococci and Staphylococcal Infections (ISSSI) in Lyon, France.

Vincent and Michael travel to San Francisco for the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), where they meet with Bill, John, and Victor to discuss tuberculosis, monitoring infectious disease outbreaks with online data, and outside-the-box approaches to antibacterial therapy.

Episode 53 of MicrobeWorld Video, filmed at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy on September 17, 2011, features a live recorded video episode of This Week in Virology (TWiV), a podcast about viruses. Host Vincent and co-host Rich, along with guests Mark and Trine, discuss science and medicine in journalism and the eradication of poliovirus at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC).

Episode 54 of MicrobeWorld Video, filmed at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy on September 17, 2011, features a live recorded video episode of This Week in Microbiology (TWiM), a podcast about life on Earth. Host Vincent and co-host Michael, along with guests Arturo, Stuart, and David converse about antimicrobial resistance and why most fungi do not cause disease.

Episode 54 of MicrobeWorld Video, filmed at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy on September 17, 2011, features a live recorded video episode of This Week in Microbiology (TWiM), a podcast about life on Earth. Host Vincent and co-host Michael, along with guests Arturo, Stuart, and David converse about antimicrobial resistance and why most fungi do not cause disease.

Episode 54 of MicrobeWorld Video, filmed at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy on September 17, 2011, features a live recorded video episode of This Week in Microbiology (TWiM), a podcast about life on Earth. Host Vincent and co-host Michael, along with guests Arturo, Stuart, and David converse about antimicrobial resistance and why most fungi do not cause disease.

On episode #16 of the podcast This Week in Microbiology, Vincent, Michael, Arturo, Stuart, and David converse about antimicrobial resistance and why most fungi do not cause disease at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC).

Episode 53 of MicrobeWorld Video, filmed at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy on September 17, 2011, features a live recorded video episode of This Week in Virology (TWiV), a podcast about viruses. Special guests include:  Trine Tsouderos, Health/Medical Writer, Chicago Tribune Mark Pallansch, Ph.D., Chief of the Enterovirus Section in the National Center for Infectious Diseases at the U.S. Centers for Disease Control Started in September 2008 by Vincent Racaniello and Dick Despommier, two science Professors at Columbia University Medical Center, the goal of the show is to have an accessible discussion about viruses that anyone can understand and enjoy. At ICAAC in Chicago, Racaniello, co-host Rich Condit and guests will be highlighting and commenting on some of the most exciting virology at the conference.

Episode 53 of MicrobeWorld Video, filmed at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy on September 17, 2011, features a live recorded video episode of This Week in Virology (TWiV), a podcast about viruses. Special guests include:  Trine Tsouderos, Health/Medical Writer, Chicago Tribune Mark Pallansch, Ph.D., Chief of the Enterovirus Section in the National Center for Infectious Diseases at the U.S. Centers for Disease Control Started in September 2008 by Vincent Racaniello and Dick Despommier, two science Professors at Columbia University Medical Center, the goal of the show is to have an accessible discussion about viruses that anyone can understand and enjoy. At ICAAC in Chicago, Racaniello, co-host Rich Condit and guests will be highlighting and commenting on some of the most exciting virology at the conference.

Vincent, Rich, Mark, and Trine discuss science and medicine in journalism and the eradication of poliovirus at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC).

MicrobeWorld Video and This Week in Virology team up to bring you a tour of the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in Boston. In this episode the host of TWiV, Vincent Racaniello, speaks with exhibitors and visitors, including Professors Derek Smith, Michael Schmidt, Frederick Hayden, and Myra McClure. Host links Vincent Racaniello Links for this episode: 50th ICAAC ICAAC daily press conference videos (including Prof. Myra McClure) Antigenic cartography Antimicrobial properties of copper

MicrobeWorld Video and This Week in Virology team up to bring you a tour of the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in Boston. In this episode the host of TWiV, Vincent Racaniello, speaks with exhibitors and visitors, including Professors Derek Smith, Michael Schmidt, Frederick Hayden, and Myra McClure. Host links Vincent Racaniello Links for this episode: 50th ICAAC ICAAC daily press conference videos (including Prof. Myra McClure) Antigenic cartography Antimicrobial properties of copper

MicrobeWorld Video and This Week in Virology team up to bring you a tour of the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in Boston. In this episode the host of TWiV, Vincent Racaniello, speaks with exhibitors and visitors, including Professors Derek Smith, Michael Schmidt, Frederick Hayden, and Myra McClure. Host links Vincent Racaniello Links for this episode: 50th ICAAC ICAAC daily press conference videos (including Prof. Myra McClure) Antigenic cartography Antimicrobial properties of copper

On episode #99 of the podcast This Week in Virology, Vincent tours the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), speaking with exhibitors and visitors, including Professors Derek Smith, Michael Schmidt, Frederick Hayden, and Myra McClure. Host links Vincent Racaniello Links for this episode: 50th ICAAC ICAAC daily press conference videos (including Prof. Myra McClure) Antigenic cartography Antimicrobial properties of copper

Dr. Anthony Fauci is the director of NIAID – the National Institutes for Allergy and Infectious Disease – where he is also Chief of the Laboratory of Immunoregulation. Dr. Fauci’s research interests lie primarily in the molecular mechanisms of HIV and AIDS, and he has published extensively on the interactions of HIV with the immune system. He’ll be speaking at the opening session of ICAAC – the Interscience Conference on Antimicrobial Agents and Chemotherapy – on October 25 in Washington DC, where he’ll describe some of the remaining challenges in the fight against HIV, tuberculosis, and antibiotic resistant microbes. Dr. Fauci is not only a researcher, he is also an important player in science policy in the U.S. He was a primary architect of PEPFAR, the President’s Emergency Plan for AIDS Relief, a program that received reauthorization and has a budget of $48 billion for HIV/AIDS, tuberculosis, and malaria around the world. In honor of his efforts to improve our understanding and treatment of HIV and AIDS, Dr. Fauci was recently awarded the Presidential Medal of Freedom, the nation’s highest civil award. In this interview, I talked with Dr. Fauci about progress in managing infectious disease on a global scale, why it’s the “devil you don’t know” that is still the scariest infectious disease of all, and about the roles of abstinence education and condom awareness in PEPFAR.

Audio Journal of Medicine, September 21st, 2007 Reporting from: 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, 2007 BORIS: A. baumanni Highly Resistant β-Lactamase and Varying Susceptibility Patterns JANE HATA, bioMéríeux Inc, Durham REFERENCE: Slide Session C2-1360/ICAAC Congress 2007 Chicago 16-20 September Reports from the BORIS study call for ongoing surveillance of multi-drug resistant Acinetobacter Baumanii. Investigators found varying susceptibility and resistance patterns across the United States that highlight the organisms ability to adapt. Nicola Solomon spoke with Jane Hata of bioMéríeux.

Audio Journal of Medicine, September 21st, 2007 Reporting from: 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, 2007 Broad Approach, Including Computer System, to Improve Hospital Hygiene YEHUDA CARMELI, Tel-Aviv Medical Center REFERENCE: Abstract K-1373/ICAAC Congress 2007 Chicago 16-20 September Hospitals can prevent significant numbers of infections by taking up a multi-faceted approach, including the use of a computer program to guide the isolation of patients. Derek Thorne spoke to Yehuda Carmeli of the Tel-Aviv Medical Center about his hospital’s experience.

Audio Journal of Medicine, September 21st, 2007 Reporting from: 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, 2007 Which HIV Treatment is Best for Patients with HIV and Hepatitis C? JUAN BERENGUER, Hospital Gregorio Marañón, Madrid REFERENCE: Abstract V-1385/ICAAC Congress 2007 Chicago 16-20 September A retrospective study has thrown doubt on the theory that protease inhibitors (PIs) are a preferable antiretroviral treatment for patients co-infected with HIV and Hepatitis C virus. Previous research had suggested that PIs had a more beneficial effect on liver fibrosis than NNRTIs, but a study based at the Hospital Gregorio Marañón in Madrid has found the opposite. Derek Thorne discussed the data with Juan Berenguer.

Audio Journal of Medicine, September 21st, 2007 Reporting from: 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, 2007 Colistin Use Linked to Outbreak of Rare Hospital Infection RAMON GUEVARA, Los Angeles County Department of Public Health REFERENCE: Abstract K-1942/ICAAC Congress 2007 Chicago 16-20 September A report on a hospital outbreak involving a rare pathogen, which was presented at ICAAC, may have an important message for the whole field of infection control. Elizabethkingia Meningoseptica was found in a Los Angles hospital outbreak in 2006 and its emergence was linked to the use of colistin. So was this antibiotic selecting for the pathogen? Derek Thorne spoke with Ramon Guevara of Los Angeles County Department of Public Health.

Audio Journal of Medicine, September 18th, 2007 Reporting from: 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, 2007 Monoclonal Antibody to Help Treat HIV? JEFFREY JACOBSON, Drexel University College of Medicine, Philadelphia REFERENCE: Interscience Conference on Antimicrobial Agents and Chemotherapy, 17 – 20 September 2007, Chicago Could a monoclonal antibody have a role to play in HIV treatment? Early data on the PRO 140 antibody, presented at ICAAC, show that it does give responses. Derek Thorne discussed this news approach with Jeffrey Jacobson of Drexel University College of Medicine, Philadelphia.

Audio Journal of Medicine, September 18th, 2007 Reporting from: 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, 2007 Maraviroc for HIV: Responses at 48 Weeks JACOB LALEZARI, Quest Clinical Research, San Francisco REFERENCE: Interscience Conference on Antimicrobial Agents and Chemotherapy, 17 – 20 September 2007, Chicago Maraviroc could be a useful new drug for the treatment of some HIV infections, according to Jacob Lalezari of Quest Clinical Research in San Francisco. He presented 48 week results from the MOTIVATE 1 study and Derek Thorne spoke to him at ICAAC in Chicago

Audio Journal of Medicine, September 18th, 2007 Reporting from: 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, 2007 Starting Antiretroviral Therapy Can Trigger Leprosy DIANA LOCKWOOD, London School of Hygiene and Tropical Medicine REFERENCE: Interscience Conference on Antimicrobial Agents and Chemotherapy, 17 – 20 September 2007, Chicago ICAAC delegates heard that ‘hidden’ leprosy can be triggered in some patients who are receiving HIV antiretroviral therapy. So what might this mean for the countries that are rolling out this therapy to large numbers of people? Derek Thorne discussed the issue with Diana Lockwood of the London School of Hygiene and Tropical Medicine.

Audio Journal of Medicine, September 18th, 2007 Reporting from: 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, 2007 Bortezomib for Multiple Myeloma Can Cause Reactivation of Viruses GEORG HÄRTER, University Hospital, Ulm REFERENCE: Interscience Conference on Antimicrobial Agents and Chemotherapy, 17 – 20 September 2007, Chicago For patients with multiple myeloma being treated with the proteasome inhibitor bortezomib, doctor’s should be wary of viral reactivation – and they should give antiviral prophylaxis in all cases. This finding was unveiled at ICAAC by Georg Härter from the University Hospital in Ulm, and he shared his data with Derek Thorne.

Audio Journal of Medicine, September 18th, 2007 Reporting from: 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, 2007 Nosocomial Clostridrium Difficile: Reduce by Cleaning with Household Bleach DONNA HACEK, Evanston Hospital, Evanston IL REFERENCE: Slide Session 42 K-608 Thorough, all surface bleach cleaning helps to achieve a significant and sustained reduction in nosocomial C. difficile infections according to a study from Evanston Hospital. Nicola Solomon discussed the results of this simple technique with Donna Hacek.

Audio Journal of Global Health Issues, September 19th, 2007 Reporting from: 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, 2007 Vancomycin: New Guidelines May Induce Kidney Damage MEGAN NGUYEN, Western University of Health Sciences, Pomona REFERENCE: Poster Session 104 K-1096/ICAAC Congress 2007 Chicago 16-20 September New vancomycin guidelines that recommend using higher doses may cause kidney damage according to a study presented at the 2007 ICAAC meeting. Nicola Solomon discussed this new finding with Megan Nguyen of Western University of Health Sciences.

Audio Journal of Medicine, September 18th, 2007 Reporting from: 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, 2007 MRSA: Fight Superbug Using Hydrogen Peroxide Vapour JON OTTER, Bioquell Ltd, Andover UK REFERENCE: Poster Session 033 K-464, ICAAC 2007 Chicago 17-20 September An investigation looking at hydrogen peroxide vapour for sterilisation in hospital areas at risk of an outbreak of MRSA revealed that it can significantly reduce environmental contamination. Nicola Solomon discussed this new technique with Jon Otter of Bioquell Ltd.