Podcasts about TB

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Latest podcast episodes about TB

Scotland's Farm Advisory Service Podcast
Stock Talk - Livestock Health: Laying it All Out

Scotland's Farm Advisory Service Podcast

Play Episode Listen Later Jul 25, 2025 46:38


Welcome to Stock Talk hosted by Principal Consultant Kirsten Williams. On today's episode Kirsten is joined by Colin Mason (Veterinary Centre Manager, SRUC). This episode focuses on livestock health and covers BVD eradication, show biosecurity, dairy beef calves, TB, Bluetongue and Schmallenberg virus. Episode Timestamps 00.44 BVD eradication (phase 6) 10.08 Top tips for biosecurity of show animals 16.20 Health of dairy beef calves 18.23 Colostrum management 20.45 Blood tests for calves 25.05 Weight for age and average DLWG 27.29 Lung scanning 28.53 Tuberculosis (TB) 31.42 Bluetongue 35.36 Schmallenberg 40.23 Managing calf groups to reduce disease risk FAS Resources BVD Eradication Scheme Update (YouTube.com)Other Resources BVD Guidance | ScotEID GOV.scot - bovine viral diarrhoea - bvd Dairy beef booklet - SAC Consulting GOV.uk - bluetongue information and guidance for livestock keepers Bluetongue Virus Hub - Ruminant Health & Welfare Schmallenberg virus - GOV.UK ibTB - Mapping bovine TB (bTB) in England and Wales   For more information, visit  www.FAS.scot Facebook: @FASScot National Advice Hub Phone: 0300 323 0161 Email: advice@fas.scot

The Peptide Podcast
VIP for Pain

The Peptide Podcast

Play Episode Listen Later Jul 24, 2025 4:36


Thank you for listening to The Peptide Podcast. If you enjoyed the show and want to support what we do, head over to our Partners Page. You'll find some amazing brands we trust—and by checking them out, you're helping us keep the podcast going. Today, we're focusing on an often-overlooked peptide called VIP, short for Vasoactive Intestinal Peptide. The name might sound technical, but this peptide plays some important roles in the body. It helps regulate inflammation, supports nerve function, improves blood flow by relaxing blood vessels, and may even have benefits for things like chronic pain, including back pain. Let's get into it. What is VIP? We've talked about VIP before on a previous podcast, but it's been awhile and I'd like to start with the basics as a refresher.  VIP is a 28-amino acid neuropeptide that acts like a signaling molecule in both the central and peripheral nervous systems. Think of it like a chemical messenger that can influence a lot of different body systems. VIP belongs to the glucagon/secretin peptide superfamily, and it's found throughout the body, including your brain, intestines, lungs, and immune cells. Now, what does VIP actually do? Well it does quite a bit. VIP works by binding to specific receptors on cells—called VPAC1 and VPAC2—which trigger a chain reaction inside the body through something known as the cyclic AMP pathway. Once activated:  It relaxes smooth muscles, which helps open up blood vessels (vasodilation) and airways (bronchodilation) It stimulates secretion of water and electrolytes in places like the gut and pancreas—so yes, it helps with digestion too It's a major immune modulator, calming inflammation by regulating immune cell behavior  Neuroprotective role, supporting the survival and adaptability of neurons VIP in Medicine – What's the Buzz? VIP has been studied in a variety of conditions. Inflammatory diseases like rheumatoid arthritis and Crohn's Neurodegenerative conditions like Alzheimer's and Parkinson's Autoimmune diseases like osteoarthritis Respiratory conditions like pulmonary arterial hypertension (PAH), asthma, and chronic obstructive pulmonary disease (COPD) or due to mold toxicity But today, we're zooming in on something more tangible for a lot of people—back pain. VIP and Back Pain – What Do We Know? Let's get into the science here. VIP has recently caught attention for its potential role in intervertebral disc degeneration, which is one of the top causes of chronic low back pain. A 2024 study found that VIP receptors were significantly reduced in degenerated human discs—which is kind of a red flag. When VIP was given to mice for four weeks, researchers saw slowed degeneration, better structural proteins like aggrecan, and overall healthier discs on imaging. Promising, right? But here's the catch—this was a preclinical animal study. We still need human trials to confirm it works outside the lab. VIP and Joint Pain And when it comes to VIP and joint pain, there's a bit more research on VIP and osteoarthritis, especially when the spine is involved. In OA models, VIP was shown to lower pro-inflammatory cytokines—those molecules that contribute to pain and make joints hurt. But here's where it gets complicated: some studies report that VIP accumulation in joints might actually worsen pain. So... it's a bit of a paradox. So what's the takeaway? VIP can be helpful—but its role in pain management seems to depend on how much, where, and what kind of pain we're talking about. VIP in Peptide Therapy – Real-World Use? In peptide clinics—especially those using integrative or regenerative medicine approaches—VIP is sometimes part of treatment protocols for nerve-related pain and inflammation. It's often paired with other peptides like BPC-157 and TB-500. You can find some clinics that list VIP as a go-to for chronic pain, including back pain. But here's the reality check, clinical data is limited, success is anecdotal, it's pricey and results can vary from person to person. So while VIP might help reduce inflammation and slow tissue degeneration, it's not a substitute for tried-and-true pain management peptides like BPC-157. Thank you for listening to The Peptide Podcast. If you enjoyed the show and want to support what we do, head over to our Partners Page. You'll find some amazing brands we trust—and by checking them out, you're helping us keep the podcast going.  Until next time, be well, and as always, have a happy, healthy week.

Dear Hank & John
416: The Free Will Episode

Dear Hank & John

Play Episode Listen Later Jul 23, 2025 42:05


Why do fish jump out of the water? What do I talk about in therapy? If the whole world quarantined itself for six weeks, would all viruses die out? If I want to donate to the TB cause, what is the best organization to do that with? Does a place without wind exist? Why does diet Dr. Pepper taste so differently when it is cold versus when it is room temperature? What do I do when it is my circus, but not my monkeys? …Hank and John Green have answers!If you're in need of dubious advice, email us at hankandjohn@gmail.com.Join us for monthly livestreams at patreon.com/dearhankandjohn.Follow us on Twitter! twitter.com/dearhankandjohnSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Hoje no TecMundo Podcast
GPS DO BRASIL VEM AÍ! DELL sofre VAZAMENTO, PIXEL 10 e FOLD 7 surpreendem; IA no Galaxy Watch!

Hoje no TecMundo Podcast

Play Episode Listen Later Jul 22, 2025 12:46


Donald Trump pode 'desligar' o sinal do GPS no Brasil? Tire o GPS da cabeça, nosso colunista alerta! Governo planeja criar 'GPS nacional' para reduzir a dependência de tecnologias estrangeiras, Dell é atacada por ransomware e vazam 1,3 TB de dados; Google mostra o Pixel 10 com nova câmera tripla e design repaginado; Galaxy Z Fold 7: novo celular pode ser dobrado 500 mil vezes sem receber nenhum dano; IA Gemini vai chegar aos modelos mais antigos do Galaxy Watch, saiba como instalar.

Rio Bravo qWeek
Episode 198: Fatigue

Rio Bravo qWeek

Play Episode Listen Later Jul 18, 2025 31:17


Episode 198: Fatigue.  Future doctors Redden and Ibrahim discuss with Dr. Arreaza the different causes of fatigue, including physical and mental illnesses. Dr. Arreaza describes the steps to evaluate fatigue. Some common misconceptions are explained, such as vitamin D deficiency and “chronic Lyme disease”. Written by Michael Ibrahim, MSIV, and Jordan Redden, MSIV, Ross University School of Medicine. Edits and comments by Hector Arreaza, MDYou are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.Dr. Arreaza: Today is a great day to talk about fatigue. It is one of the most common and most complex complaints we see in primary care. It involves physical, mental, and emotional health. So today, we're walking through a case, breaking down causes, red flags, and how to work it up without ordering the entire lab catalog.Michael:Case: This is a 34-year-old female who comes in saying, "I've been feeling drained for the past 3 months." She says she's been sleeping 8 hours a night but still wakes up tired. No recent illnesses, no weight loss, fever, or night sweats. She denies depression or anxiety but does report a lot of work stress and taking care of her two little ones at home. She drinks 2 cups of coffee a day, doesn't drink alcohol, and doesn't use drugs. No medications, just a multivitamin. Regular menstrual cycles—but she's noticed they've been heavier recently.Jordan:Fatigue is a persistent sense of exhaustion that isn't relieved by rest. It's different from sleepiness or muscle weakness.Classification based on timeline:    •   Acute fatigue: less than 1 month    •   Subacute: 1 to 6 months    •   Chronic: more than 6 monthsThis patient's case is subacute—going on 3 months now.Dr. Arreaza:And we can think about fatigue in types:    •   Physical fatigue: like muscle tiredness after activity    •   Mental fatigue: trouble concentrating or thinking clearly (physical + mental when you are a medical student or resident)    •    Pathological fatigue: which isn't proportional to effort and doesn't get better with restAnd of course, there's chronic fatigue syndrome, also called myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), which is a diagnosis of exclusion after 6 months of disabling fatigue with other symptoms.Michael:The differential is massive. So, we can also group it by systems.Jordan:Let's run through the big ones.Endocrine / Metabolic Causes    • Hypothyroidism: A classic cause of fatigue. Often associated with cold intolerance, weight gain, dry skin, and constipation. May be subtle and underdiagnosed, especially in women.    • Diabetes Mellitus: Both hyperglycemia and hypoglycemia can cause fatigue. Look for polyuria, polydipsia, weight loss, or blurry vision in undiagnosed diabetes.    • Adrenal Insufficiency: Think of this when fatigue is paired with hypotension, weight loss, salt craving, or hyperpigmentation. Can be primary (Addison's) or secondary (e.g., due to long-term steroid use).Michael: Hematologic Causes    • Anemia (especially iron deficiency): Very common, especially in menstruating women. Look for fatigue with pallor, shortness of breath on exertion, and sometimes pica (craving non-food items).     • Vitamin B12 or Folate Deficiency: B12 deficiency may present with fatigue plus neurologic symptoms like numbness, tingling, or gait issues. Folate deficiency tends to present with megaloblastic anemia and fatigue.    • Anemia of Chronic Disease: Seen in patients with chronic inflammatory conditions like RA, infections, or CKD. Typically mild, normocytic, and improves when the underlying disease is treated.Michael: Psychiatric Causes    • Depression: A major driver of fatigue, often underreported. May include anhedonia, sleep disturbance, appetite changes, or guilt. Sometimes presents with only somatic complaints.    • Anxiety Disorders: Mental fatigue, poor sleep quality, and hypervigilance can leave patients feeling constantly drained.    • Burnout Syndrome: Especially common in caregivers, healthcare workers, and educators. Emotional exhaustion, depersonalization, and reduced personal accomplishment are key features.Jordan: Infectious Causes    • Epstein-Barr Virus (EBV):Mononucleosis is a well-known cause of fatigue, sometimes lasting weeks. May also have sore throat, lymphadenopathy, and splenomegaly.    • HIV:Consider it in high-risk individuals. Fatigue can be an early sign, along with weight loss, recurrent infections, or night sweats.    • Hepatitis (B or C):Can present with chronic fatigue, especially if liver enzymes are elevated. Screen at-risk individuals.    • Post-viral Syndromes / Long COVID:Fatigue that lingers for weeks or months after viral infection. Often, it includes brain fog, muscle aches, and post-exertional malaise.Important: Chronic Lyme disease is a controversial term without a consistent clinical definition and is often used to describe patients with persistent, nonspecific symptoms not supported by objective evidence of Lyme infection. Leading medical organizations reject the term and instead recognize "post-treatment Lyme disease syndrome" (PTLDS) for persistent symptoms following confirmed, treated Lyme disease, emphasizing that prolonged antibiotic therapy is not effective. Research shows no benefit—and potential harm—from extended antibiotic use, and patients with unexplained chronic symptoms should be thoroughly evaluated for other possible diagnoses.Michael: Cardiopulmonary Causes    •   Congestive Heart Failure (CHF): Fatigue from poor perfusion and low cardiac output. Often comes with dyspnea on exertion, edema, and orthopnea.    •   Chronic Obstructive Pulmonary Disease (COPD): Look for a smoking history, chronic cough, and fatigue from hypoxia or the work of breathing.    •   Obstructive Sleep Apnea (OSA): Daytime fatigue despite adequate hours of sleep. Patients may snore, gasp, or report morning headaches. High suspicion in obese or hypertensive patients.Jordan:Autoimmune / Inflammatory Causes    •   Systemic Lupus Erythematosus (SLE): Fatigue is often an early symptom. May also see rash, arthritis, photosensitivity, or renal involvement.    •   Rheumatoid Arthritis (RA): Fatigue from systemic inflammation. Morning stiffness, joint pain, and elevated inflammatory markers point to RA.    •   Fibromyalgia: A chronic pain syndrome with widespread tenderness, fatigue, nonrestorative sleep, and sometimes cognitive complaints ("fibro fog").Cancer / Malignancy    •   Leukemia, lymphoma, or solid tumors: Fatigue can be the first symptom, often accompanied by weight loss, night sweats, or unexplained fevers. Consider when no other cause is evident.Michael:Medications:Common culprits include:    ◦   Beta-blockers: Can slow heart rate too much.    ◦   Antihistamines: Sedating H1 blockers like diphenhydramine.    ◦   Sedatives or sleep aids: Can cause grogginess and daytime sedation.    •   Substance Withdrawal: Fatigue can be seen in withdrawal from alcohol, opioids, or stimulants. Caffeine withdrawal, though mild, can also contribute.Dr. Arreaza:Whenever we evaluate fatigue, we need to keep an eye out for red flags. These should raise suspicion for something more serious:    •   Unintentional weight loss    •   Night sweats    •   Persistent fever    •   Neurologic symptoms    •   Lymphadenopathy    •   Jaundice    •   Palpitations or chest painThis patient doesn't have these—but that doesn't mean we stop here.Dr. Arreaza:Those are a lot of causes, we can evaluate fatigue following 7 steps:Characterize the fatigue.Look for organic illness.Evaluate medications and substances.Perform psychiatric screening.Ask questions about quantity and quality of sleep.Physical examination.Undertake investigations.So, students, do we send the whole lab panel?Michael:Not necessarily. Labs should be guided by history and physical. But here's a good initial panel:    •   CBC: To check for anemia or infection    • TSH: Screen for hypothyroidism    • CMP: Look at electrolytes, kidney, and liver function    • Ferritin and iron studies    • B12, folate    • ESR/CRP for inflammation (not specific)    • HbA1c if diabetes is on the radarJordan:And if needed, consider:    • HIV, EBV, hepatitis panel    • ANA, RF    • Cortisol or ACTH stimulation testImaging? Now that's rare—unless there are specific signs. Like chest X-ray for possible cancer or TB, or sleep study if you suspect OSA.Dr. Arreaza:Unaddressed fatigue isn't just inconvenient. It can impact on quality of life, affect job performance, lead to mood disorders, delay diagnosis of serious illness, increase risk of accidents—especially driving. So, don't ignore your patients with fatigue!Jordan:And some people—like women, caregivers, or shift workers—are especially at risk.Michael:The cornerstone of treatment is addressing the underlying cause.Jordan:If it's iron-deficiency anemia—treat it. If it's depression—get mental health involved. But there's also: Lifestyle Support: Better sleep hygiene, light physical activity, mindfulness or CBT for stress, balanced nutrition—especially iron and protein, limit caffeine and alcoholDr. Arreaza:Sometimes medications help—but rarely. And for chronic fatigue syndrome, the current best strategies are graded exercise therapy and CBT, along with managing specific symptoms. Beta-alanine has potential to modestly improve muscular endurance and reduce fatigue in older adults, but more high-quality research is needed.SSRI: fluoxetine and sertraline. Iron supplements: Even without anemia, but low ferritin [Anecdote about low ferritin patient]Jordan:This case reminds us to take fatigue seriously. In her case, it may be multifactorial—work stress, caregiving burden, and possibly iron-deficiency anemia. So, how would we wrap up this conversation, Michael?Michael:We don't need to order everything under the sun. A focused history and exam, targeted labs, and being alert to red flags can guide us.Jordan:And don't forget the basics—sleep, stress, and nutrition. These are just as powerful as any prescription.Dr. Arreaza:We hope today's episode on fatigue has given you a clear framework and some practical tips. If you enjoyed this episode, share it and subscribe for more evidence-based medicine!Jordan:Take care—and get some rest~___________________________Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:DynaMed. (2023). Fatigue in adults. EBSCO Information Services. https://www.dynamed.com (Access requires subscription)Jason, L. A., Sunnquist, M., Brown, A., Newton, J. L., Strand, E. B., & Vernon, S. D. (2015). Chronic fatigue syndrome versus systemic exertion intolerance disease. Fatigue: Biomedicine, Health & Behavior, 3(3), 127–141. https://doi.org/10.1080/21641846.2015.1051291Kroenke, K., & Mangelsdorff, A. D. (1989). Common symptoms in ambulatory care: Incidence, evaluation, therapy, and outcome. The American Journal of Medicine, 86(3), 262–266. https://doi.org/10.1016/0002-9343(89)90293-3National Institute for Health and Care Excellence. (2021). Myalgic encephalomyelitis (or encephalopathy)/chronic fatigue syndrome: Diagnosis and management (NICE Guideline No. NG206). https://www.nice.org.uk/guidance/ng206UpToDate. (n.d.). Approach to the adult patient with fatigue. Wolters Kluwer. https://www.uptodate.com (Access requires subscription)Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/.

BDGE Fantasy Football
Under the Radar Breakout Fantasy Stars in 2025

BDGE Fantasy Football

Play Episode Listen Later Jul 17, 2025 25:58


Deposit $10+ with code “BDGE” and play on our partner website to get the 2025 BDGE Fantasy Football Draft Guide for free! https://tinyurl.com/3add4t6zIf you live in a state where they aren't live, you can pre-order the draft guide for a discounted price straight from our website through August 1st: https://bdge.co/draft_guides/20250:00 - its rude to skip introductions1:50 - emeka egbuka - TB, WR7:40 - kaleb johnson - PIT, RBget the draft guide here: https://tinyurl.com/3add4t6z11:45 - cedric tillman - CLV, WR13:30 - j.j. mccarthy - MIN, QB15:38 - cam skattebo - NYG, RB17:38 - kyle williams - NE, WR20:08 - jayden higgins - HOU, WR21:22 - honorable mentionssubscribe to the bdge dynasty channel: https://ytube.io/3pZklisten to the bdge dynasty podcast: https://bityl.co/NzJ1bdge nfl trivia youtube channel: https://ytube.io/3jmJjoin the BDGE discord: https://discord.gg/77BxrqCF6Fsubscribe to the BDGE podcast | https://linktr.ee/bdgefollow me on the socials | https://linktr.ee/nickercolanoContact▪️ advertising/business | business@bdge.co (don't send fantasy questions here)▪️ i do answer fantasy Q's on our discord | https://discord.gg/AvpY3QJTAythis video is about (bdge,nick ercolano,fantasypros,fantasy flock,fantasy footballers,bdge fantasy football,2025 fantasy football,mock draft 2025 fantasy football,2025 fantasy football rankings,fantasy football breakouts,kaleb johnson fantasy,emeka egbuka fantasy,fantasy football sleepers,fantasy football 2025 rankings,fantasy football rankings,2025 fantasy football draft,fantasy football breakout players,top fantasy sleepers)Support this podcast at — https://redcircle.com/bdge-fantasy-football/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Commonwealth Club of California Podcast
Dr. Monica Gandhi: The Impact on American Science and Medicine of the Current Administration

Commonwealth Club of California Podcast

Play Episode Listen Later Jul 17, 2025 53:38


Research funded by the federal government has been crucial in many of the defining technologies of our time: the internet, A.I., crispr, Ozempic, and the mRNA vaccines first used widely in the COVID pandemic. Between 2010 and 2019, more than 350 drugs were approved in the United States, and virtually all of them could trace their roots to the National Institutes of Health (NIH). Now this administration is endangering our health by cutting funds to academic medical centers. Moreover, there are threats to Medicaid, as well as ongoing cuts to the Centers for Disease Control (CDC). Many universities have paused hiring due to the uncertainty at the NIH and are curtailing graduate programs. Biotech investors are warning of a contraction in medical innovation. NIH grants have been terminated on ideological grounds, which have resulted in clinical trials shutting down. Global health programs worldwide have been cut. A discussion on these destructive policies on medicine in our country is needed. About the Speaker Monica Gandhi M.D., M.P.H., is a professor of medicine and associate chief in the Division of HIV, Infectious Diseases, and Global Medicine at the University of California, San Francisco (UCSF). She is also the director of the UCSF Center for AIDS Research (CFAR) and the medical director of the HIV Clinic ("Ward 86") at San Francisco General Hospital. She serves as the associate program director of the ID fellowship at UCSF. Her research focuses on HIV treatment and prevention optimization, HIV and women, adherence measurement in HIV and TB, adherence interventions, and on optimizing the use of long-acting antiretroviral therapy (ART). She is a long-standing NIH-funded researcher. Commonwealth Club World Affairs of California is a nonprofit public forum; we welcome donations made during registration to support the production of our programming. A Health & Medicine Member-led Forum program. Forums and Chapters at the Club are organized and run by volunteer programmers who are members of The Commonwealth Club, and they cover a diverse range of topics. Learn more about our Forums. Commonwealth Club World Affairs is a public forum. Any views expressed in our programs are those of the speakers and not of Commonwealth Club World Affairs. OrganizerMichael Baker  Learn more about your ad choices. Visit megaphone.fm/adchoices

The Lancet Respiratory Medicine
Carole Mitnick & Lorenzo Guglielmetti on the ENDTB-Q trial

The Lancet Respiratory Medicine

Play Episode Listen Later Jul 16, 2025 18:45


Carole Mitnick & Lorenzo Guglielmetti join Ari Colosio, deputy editor of The Lancet Respiratory Medicine, to discuss the ENDTB-Q trial to evaluate the efficacy and safety of a drug regiment to treat TB in individuals with pre-extensively drug-resistant tuberculosis.Read the full article:https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00194-8/fulltext?dgcid=buzzsprout_icw_podcast_July_25_lanresContinue this conversation on social!Follow us today at...https://thelancet.bsky.social/https://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

trial tb mitnick lancet respiratory medicine
The Jefferson Exchange
Why do thousands of jail and prison sentences become death sentences?

The Jefferson Exchange

Play Episode Listen Later Jul 14, 2025 30:16


Jails and prisons are often hotspots for the spread of communicable diseases such as TB and COVID-19.

KTOO News Update
Newscast – Thursday, July 10, 2025

KTOO News Update

Play Episode Listen Later Jul 11, 2025


In this newscast: The Juneau Assembly is moving forward with a plan to ask voters this fall whether to implement a new seasonal sales tax system next year; Like much of Alaska, Juneau has its share of disasters and emergencies. Part of living here is planning ahead for scenarios that may require evacuating your home. Juneau Animal Rescue wants to inform residents about how best to prepare to evacuate their pets too; An immigration detainee originally from Peru and recently held in Alaska was later hospitalized in Washington state with tuberculosis, according to his attorney. State corrections officials deny claims he contracted TB at the Anchorage jail; Multiple research vessels are out in the Bering Sea and Gulf of Alaska this summer conducting surveys that inform stock assessments for fisheries managers. One of those surveys only happens every two years and comes during a challenging time for the National Oceanic and Atmospheric Administration; A fire burned through the public safety building and city jail in the Western Alaska coastal community of Chevak early Tuesday morning. City officials say the building is a total loss.

RTÉ - Barrscéalta
Béibhinn Nic Giolla Chearra, Lily Mae Ní Ghallachóir & Marie Uí Chearnaigh.

RTÉ - Barrscéalta

Play Episode Listen Later Jul 11, 2025 11:38


Tá Béibhinn agus Lilly Mae ar mire glan faoi imreoir Dhún na nGall Dáire Ó Baoill agus tá na girseachaí linn sa stiúideo agus rap speisialta cumtha acu don deireadh seachtaine i bPáirc an Chrócaigh.

bp tb dh chr lily mae baoill
Ozarks at Large
Together Arkansas mitigates opioid addiction — Birds' food impacts health

Ozarks at Large

Play Episode Listen Later Jul 11, 2025 54:59


On today's show, we learn more about a new website that prioritizes opioid recovery tools in the workplace. Also, how a bird's diet can affect its ability to tolerate infection. Plus, our weekly roundup with TB&P's Michael Tilley about the latest headlines from the River Valley.

Tecnocast
O ChatGPT está te deixando mais preguiçoso?

Tecnocast

Play Episode Listen Later Jul 9, 2025 77:35


Você já parou pra pensar em como o ChatGPT afeta o seu cérebro? Segundo um estudo recente do MIT, a ferramenta pode ter um impacto negativo em áreas como criatividade e pensamento crítico.A IA torna possível algo até então impensável: a terceirização do processo cognitivo. Assim, tarefas que antes exigiriam raciocínio são entregues a chatbots, que fazem o trabalho por nós. A tecnologia estaria, portanto, nos deixando mais preguiçosos.Mas quais serão as consequências disso a longo prazo? Como lidar com esse fenômeno em ambientes como escolas e universidades, onde o esforço mental é decisivo para o aprendizado? E como resistir à tentação de entregar até mesmo tarefas simples nas mãos da IA? É o que discutimos no episódio de hoje. Dá o play e vem com a gente! ParticipantesThiago MobilonJosué de Oliveira Ana MarquesLaura Canal Mande seu recadoGrupos da Caixa Postal do Tecnocast: Telegram: t.me/caixapostaltecnocast WhatsApp: tbnet.me/caixapostaltecnocast Você pode mandar comentários (inclusive em áudio, vai que você aparece no Tecnocast?), dúvidas, críticas e sugestões. Participe!Se preferir, você pode se comunicar conosco pela Comunidade e através do e-mail tecnocast@tecnoblog.net.Entre também nos Canais do TB no WhatsApp Canal do Tecnoblog Canal do Achados do TB CréditosProdução: Josué de OliveiraEdição e sonorização: Ariel LiborioArte da capa: Vitor Pádua

The Current
Why John Green is obsessed with tuberculosis

The Current

Play Episode Listen Later Jul 9, 2025 24:11


Tuberculosis is entirely curable and yet also the deadliest infectious disease in the world. That paradox has fascinated John Green, the popular YouTuber and author of The Fault in Our Stars, ever since he met a boy called Henry at a TB hospital in Sierra Leone. Green's new book, Everything is Tuberculosis, tells Henry's story and asks why this disease still kills more people every year than homicide, war, and malaria combined.

Mark Bell's Power Project
Peptides, Bioregulators, Hormones and the Future of Human Optimization

Mark Bell's Power Project

Play Episode Listen Later Jul 8, 2025 129:31


Discover how to master GLP-1 peptides for fat loss and muscle gain simultaneously in this power-packed episode of Mark Bell's Power Project!

Dr. Jockers Functional Nutrition
The Anti-Inflammatory Power of Peptides BPC-157 and TB-4 Frag with Dr. Rob Bello

Dr. Jockers Functional Nutrition

Play Episode Listen Later Jul 8, 2025 52:49


In this episode, Dr. Jockers and Dr. Rob Bello dive into the science behind BPC-157 and why it's different from conventional anti-inflammatories like NSAIDs. You'll hear how this peptide works with your body—not against it—to speed healing and reduce chronic inflammation without halting the recovery process.   You'll also discover the power of stacking BPC-157 with TB-4 Frag, a synergistic combo known as the “Wolverine Stack.” Learn how this potent pair supports tissue repair, collagen production, angiogenesis, and even hormone receptor sensitivity for faster recovery and better performance.   Curious about dosing, delivery methods, or long-term safety? Dr. Bello shares insider insights on oral bioavailability, clinical outcomes, and what makes their formulations uniquely effective—especially for athletes, autoimmune patients, and anyone dealing with chronic pain.   In This Episode: 00:00 Introduction to Inflammation and BPC 03:23 Dr. Jocker's Personal Experience with BPC 157 04:33 Interview with Dr. Rob Bello: Peptides and BPC 157 04:55 The Origin and Benefits of BPC 157 09:48 BPC 157: Mechanisms and Healing Properties 20:14 BPC 157: Dosage and Administration 28:00 Understanding Lip Polysaccharides and Inflammation 28:23 Why Most New Year's Resolutions Fail 30:24 The Role of Endotoxin Labs in Autoimmune Treatment 31:30 Exploring TB 500 and Its Benefits 37:21 The Wolverine Stack: Enhancing Healing and Recovery 46:41 Ensuring Quality and Efficacy in Supplements 51:29 Conclusion and Final Thoughts     Support your heart, brain, and immune system with Paleo Valley's Wild Caught Fish Roe, a whole food source rich in Omega-3s like EPA and DHA. It's more bioavailable and stable than traditional fish oil, offering benefits for cardiovascular health, mood, and brain function. Go to paleovalley.com/jockers for 15% off your order!   Looking to boost your digestion, immunity, and energy? Just Thrive Probiotic is the answer! Unlike most probiotics that get destroyed by stomach acid, Just Thrive is clinically proven to reach your gut 100% alive. This means better digestion, improved immunity, enhanced energy, and easier weight management. Plus, with their industry-leading 100% money-back guarantee, you've got nothing to lose. Start feeling your best today, go to justthrivehealth.com and use code JOCKERS to save 20%.   Turn on your body's ability to heal with Vibrant Blue Oils, particularly their parasympathetic blend. These natural essential oils activate your nervous system, reduce inflammation, enhance digestion, detoxification, and improve brain function. Visit vibrantblueoils.com/jockers to grab a $15 full-size bottle of their Parasympathetic Blend today!"       "BPC-157 doesn't block inflammation. It empowers the healing process by regulating inflammation where it's needed." ~ Dr. Jockers     Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean  TuneIn Radio     Resources: Get 15% off Paleovalley Fish Roe: paleovalley.com/jockers – Use code JOCKERS Save 20% on Just Thrive: justthrivehealth.com – Use code JOCKERS Visit vibrantblueoils.com/jockers and save $15 on a full-size bottle today!       Connect with Dr. Rob Bello: Website: https://bellofamilychiropractic.com/   Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/

West Wellness & Longevity
Peptides: The Ultimate Summer Skin Stack!

West Wellness & Longevity

Play Episode Listen Later Jul 8, 2025 16:16 Transcription Available


Episode Links!The Peptique is LIVE! Go to https://thepeptique.com/ to get all your research peptides .As a loyal listener use the discount code POD15 at checkout to get 15% off!Get Melanotan 1 for 40% use the discount code MELANO40, this is only good for a one time purchase and cannot be combined with any other discount codes.Have questions? Feel free to reach out to me: tarawest@thepeptique.comFollow me on instagram @westwellnessatx, @thepeptiqueThe Peptique is officially live, and I just want to take a moment to say thank you. Launching this brand has been a huge milestone—and honestly, it came with all the emotions: excitement, nerves, and a lot of behind-the-scenes hustle. But the feedback and support so far have been incredible, and I'm so grateful for this community that's continuing to grow around it.In this episode, I'm diving into one of my favorite topics for summer: skin health. Specifically, how the Glow Stack and Melanotan 1 work together as the ultimate skin optimization duo.The Glow Stack—made up of GHK-Cu, BPC-157, and TB-500—was built to support collagen production, cellular repair, and overall skin rejuvenation from the inside out. And when you pair it with Melanotan 1, a peptide that stimulates your body's natural melanin production, you're not just getting a glow—you're getting real skin protection and long-term benefits without baking in the sun.I'll break down how these peptides work, how they stack together, and why this combo is one of the most effective (and safest) ways to support skin health and that bronzed summer look—without relying on harmful UV exposure.If summer skin is on your radar, you're going to love this one.Takeaways: The Peptique was officially launched, marking a significant milestone for us today. Melanitan one is a synthetic analog that enhances melanin production for natural tanning. The Glow Stack promotes collagen production and improves skin health from cellular levels. Combining Melanitan one with the Glow Stack addresses both skin pigmentation and quality effectively.

Boston Confidential Beantown's True Crime Podcast
Karen Read Case Finally-Where do we go from here?

Boston Confidential Beantown's True Crime Podcast

Play Episode Listen Later Jul 7, 2025 35:26


Send us a textWhat a ride it's been! The most corrupt trial in American history is over. Judge Bev openly put her thumb on the scale of justice, that is simply a fact. Will she be reprimanded? counseled? questioned? No, simply no. Will there be a blue ribbon commission of Massachusetts State Police? No they've stated they'll remedy the planting of evidence, through a citizens police academy? Did you just chuckle? This IS happening. Massachusetts corruption continues unabated. That is the toughest part of the trial, NOTHING will change. Please share-yea right now!TB interviews Allan Jackson-https://bit.ly/405jZSZBrother Counsel interviews KR's civil attorneyhttps://bit.ly/4eC1kUNX-bcpbeantown Email-barry@bostonconfidential.net

VietChristian Podcast
Chúa Chỉ Như Ngài Tự Bày Tỏ (Mục Sư Trịnh Văn Khánh)

VietChristian Podcast

Play Episode Listen Later Jul 6, 2025


Tựa Đề: Chúa Chỉ Như Ngài Tự Bày Tỏ; Kinh Thánh: Xuất Ê-díp-tô Ký 32:1-10; Công-vụ các Sứ-đồ 2:1-21; Tác Giả: Mục Sư Trịnh Văn Khánh; Loạt Bài: Hội Thánh Tin Lành Trưởng Nhiệm Ân Điển

The Infectious Science Podcast
Beyond the Sequence: People, Pathogens, and Power Dynamics

The Infectious Science Podcast

Play Episode Listen Later Jul 4, 2025 73:02 Transcription Available


Send us a textThe cutting edge of infectious disease control isn't just about vaccines or treatments—it's increasingly about data. Dr. Stephen Molldrem, Assistant Professor at the Institute for Bioethics and Health Humanities, takes us deep into the world of pathogen genomics and the remarkable ethical questions that emerge when we sequence disease-causing microorganisms.What happens when genetic analysis can potentially reveal who infected whom with HIV? Why do some communities welcome these technologies while others resist them? From the controversies surrounding HIV surveillance in America to the enthusiastic adoption of TB genomics in Botswana, Dr. Molldrem reveals how the same scientific tools can take on dramatically different meanings depending on context, trust, and community involvement.The COVID-19 pandemic accelerated the global adoption of pathogen sequencing, bringing terms like "variants" and "mutations" into everyday conversation. But this technological revolution has also revealed deep inequities—when South African scientists identified the Omicron variant and transparently shared this information, their reward was travel bans rather than support. This pattern reveals how scientific advancement doesn't happen in a vacuum but within complex social and political realities.At the heart of Dr. Molldrem's work is a fundamental reminder: behind every genetic sequence is a person, a community, and a set of lived experiences. As one HIV advocacy slogan puts it, "We are people, not clusters." The challenge for public health isn't just implementing new technologies but doing so in ways that respect human dignity and build rather than undermine trust.Whether you're fascinated by the science of disease tracking, concerned about health privacy, or interested in how new technologies reshape our understanding of outbreaks, this episode offers a thought-provoking journey through the socio-technical landscape of modern infectious disease control. Join us as we explore what happens when cutting-edge science meets complex human realities.Thanks for listening to the Infectious Science Podcast. Be sure to visit infectiousscience.org to join the conversation, access the show notes, and don't forget to sign up for our newsletter to receive our free materials. We hope you enjoyed this new episode of Infectious Science, and if you did, please leave us a review on Apple Podcasts and Spotify. Please share this episode with others who may be interested in this topic! Also, please don't hesitate to ask questions or tell us which topics you want us to cover in future episodes. To get in touch, drop us a line in the comment section or send us a message on social media. Instagram @InfectscipodFacebook Infectious Science PodcastSee you next time for a new episode!

Afternoons with Pippa Hudson
Health: Stellenbosch University uses AI to help detect TB

Afternoons with Pippa Hudson

Play Episode Listen Later Jul 4, 2025 11:24 Transcription Available


Sara-Jayne Makwala King, in for Pippa Hudson speaks to Grant Theron, a professor in Clinical Mycobacteriology and Epidemiology at SU and coordinator of a project which will trial an AI-assisted device to help detect TB. Lunch with Pippa Hudson is CapeTalk’s mid-afternoon show. This 2-hour respite from hard news encourages the audience to take the time to explore, taste, read and reflect. The show - presented by former journalist, baker and water sports enthusiast Pippa Hudson - is unashamedly lifestyle driven. Popular features include a daily profile interview #OnTheCouch at 1:10pm. Consumer issues are in the spotlight every Wednesday while the team also unpacks all things related to health, wealth & the environment. Thank you for listening to a podcast from Lunch with Pippa Hudson Listen live on Primedia+ weekdays between 13:00 and 15:00 (SA Time) to Lunch with Pippa Hudson broadcast on CapeTalk https://buff.ly/NnFM3Nk For more from the show go to https://buff.ly/MdSlWEs or find all the catch-up podcasts here https://buff.ly/fDJWe69 Subscribe to the CapeTalk Daily and Weekly Newsletters https://buff.ly/sbvVZD5 Follow us on social media: CapeTalk on Facebook: https://www.facebook.com/CapeTalk CapeTalk on TikTok: https://www.tiktok.com/@capetalk CapeTalk on Instagram: https://www.instagram.com/ CapeTalk on X: https://x.com/CapeTalk CapeTalk on YouTube: https://www.youtube.com/@CapeTalk567See omnystudio.com/listener for privacy information.

WagerTalk Podcast
Total Bases | Beat the Books! Your Daily MLB Betting Fix - Predictions and Best Bets for July 3

WagerTalk Podcast

Play Episode Listen Later Jul 3, 2025 64:07


Looking for the best MLB picks, predictions, and betting tips for Thursday, July 3, 2025? Tune in to Total Bases with expert handicappers Adam Trigger, Bryan Leonard and Tokyo Brandon as they break down today's MLB matchups with sharp insights and actionable advice.0:00:00 Introduction0:02:11 TB's tirade0:05:45 New York Mets vs. Milwaukee Brewers0:14:40 Houston Astros vs. Colorado Rockies0:23:48 Minnesota Twins vs. Miami Marlins0:32:15 Los Angeles Angels vs. Atlanta Braves0:44:14 Detroit Tigers vs. Washington Nationals0:55:34 New York Yankees vs. Toronto Blue Jays1:01:29 Parlay of the Day

Core EM Podcast
Episode 211: Granulomatosis with Polyangiitis

Core EM Podcast

Play Episode Listen Later Jul 1, 2025


Granulomatosis with Polyangiitis (GPA) – Recognition and Management in the ED Hosts: Phoebe Draper, MD Brian Gilberti, MD https://media.blubrry.com/coreem/content.blubrry.com/coreem/GPA.mp3 Download Leave a Comment Tags: Rheumatology Show Notes Background A vasculitis affecting small blood vessels causing inflammation and necrosis Affects upper respiratory tract (sinusitis, otitis media, saddle nose deformity), lungs (nodules, alveolar hemorrhage), and kidneys (rapidly progressive glomerulonephritis) Can lead to multi-organ failure, pulmonary hemorrhage, renal failure Red Flag Symptoms: Chronic sinus symptoms Hemoptysis (especially bright red blood) New pulmonary complaints Renal dysfunction Constitutional symptoms (fatigue, weight loss, fever) Workup in the ED: CBC, CMP for anemia and AKI Urinalysis with microscopy (hematuria, RBC casts) Chest imaging (CXR or CT for nodules, cavitary lesions) ANCA testing (not immediately available but important diagnostically) Management: Stable patients: Outpatient workup, urgent rheumatology consult, prednisone 1 mg/kg/day Unstable patients: High-dose IV steroids (methylprednisolone 1 g daily x3 days), consider plasma exchange, cyclophosphamide or rituximab initiation, ICU admission Conditions that Mimic GPA: Goodpasture syndrome (anti-GBM antibodies) TB, fungal infections Lung malignancy Other vasculitides (EGPA, MPA, lupus)

Two Worlds Podcast
Ep: 269 ShooterCast

Two Worlds Podcast

Play Episode Listen Later Jul 1, 2025 60:07


7:09 News 24:22 Comic reviews25:41 Absolute Wonder Woman #927:51 Witcher B&TB #228:39 Ultramega #930:48 Uncanny X-Men #1631:43 Pale Knight #233:25 The Thing #235:06 Sonic the Hedgehog #7936:30 DC x Sonic #439:26 Green Lantern #2440:45 New History of the DCU #142:57 Minor Arcana #845:14 Incredible Hulk #2647:44 JLU #851:55 Superman #2754:34 What we are excited for55:53 Fantastic Four

Ground Truths
Adam Kucharski: The Uncertain Science of Certainty

Ground Truths

Play Episode Listen Later Jun 29, 2025 45:10


“To navigate proof, we must reach into a thicket of errors and biases. We must confront monsters and embrace uncertainty, balancing — and rebalancing —our beliefs. We must seek out every useful fragment of data, gather every relevant tool, searching wider and climbing further. Finding the good foundations among the bad. Dodging dogma and falsehoods. Questioning. Measuring. Triangulating. Convincing. Then perhaps, just perhaps, we'll reach the truth in time.”—Adam KucharskiMy conversation with Professor Kucharski on what constitutes certainty and proof in science (and other domains), with emphasis on many of the learnings from Covid. Given the politicization of science and A.I.'s deepfakes and power for blurring of truth, it's hard to think of a topic more important right now.Audio file (Ground Truths can also be downloaded on Apple Podcasts and Spotify)Eric Topol (00:06):Hello, it's Eric Topol from Ground Truths and I am really delighted to welcome Adam Kucharski, who is the author of a new book, Proof: The Art and Science of Certainty. He's a distinguished mathematician, by the way, the first mathematician we've had on Ground Truths and a person who I had the real privilege of getting to know a bit through the Covid pandemic. So welcome, Adam.Adam Kucharski (00:28):Thanks for having me.Eric Topol (00:30):Yeah, I mean, I think just to let everybody know, you're a Professor at London School of Hygiene and Tropical Medicine and also noteworthy you won the Adams Prize, which is one of the most impressive recognitions in the field of mathematics. This is the book, it's a winner, Proof and there's so much to talk about. So Adam, maybe what I'd start off is the quote in the book that captivates in the beginning, “life is full of situations that can reveal remarkably large gaps in our understanding of what is true and why it's true. This is a book about those gaps.” So what was the motivation when you undertook this very big endeavor?Adam Kucharski (01:17):I think a lot of it comes to the work I do at my day job where we have to deal with a lot of evidence under pressure, particularly if you work in outbreaks or emerging health concerns. And often it really pushes the limits, our methodology and how we converge on what's true subject to potential revision in the future. I think particularly having a background in math's, I think you kind of grow up with this idea that you can get to these concrete, almost immovable truths and then even just looking through the history, realizing that often isn't the case, that there's these kind of very human dynamics that play out around them. And it's something I think that everyone in science can reflect on that sometimes what convinces us doesn't convince other people, and particularly when you have that kind of urgency of time pressure, working out how to navigate that.Eric Topol (02:05):Yeah. Well, I mean I think these times of course have really gotten us to appreciate, particularly during Covid, the importance of understanding uncertainty. And I think one of the ways that we can dispel what people assume they know is the famous Monty Hall, which you get into a bit in the book. So I think everybody here is familiar with that show, Let's Make a Deal and maybe you can just take us through what happens with one of the doors are unveiled and how that changes the mathematics.Adam Kucharski (02:50):Yeah, sure. So I think it is a problem that's been around for a while and it's based on this game show. So you've got three doors that are closed. Behind two of the doors there is a goat and behind one of the doors is a luxury car. So obviously, you want to win the car. The host asks you to pick a door, so you point to one, maybe door number two, then the host who knows what's behind the doors opens another door to reveal a goat and then ask you, do you want to change your mind? Do you want to switch doors? And a lot of the, I think intuition people have, and certainly when I first came across this problem many years ago is well, you've got two doors left, right? You've picked one, there's another one, it's 50-50. And even some quite well-respected mathematicians.Adam Kucharski (03:27):People like Paul Erdős who was really published more papers than almost anyone else, that was their initial gut reaction. But if you work through all of the combinations, if you pick this door and then the host does this, and you switch or not switch and work through all of those options. You actually double your chances if you switch versus sticking with the door. So something that's counterintuitive, but I think one of the things that really struck me and even over the years trying to explain it is convincing myself of the answer, which was when I first came across it as a teenager, I did quite quickly is very different to convincing someone else. And even actually Paul Erdős, one of his colleagues showed him what I call proof by exhaustion. So go through every combination and that didn't really convince him. So then he started to simulate and said, well, let's do a computer simulation of the game a hundred thousand times. And again, switching was this optimal strategy, but Erdős wasn't really convinced because I accept that this is the case, but I'm not really satisfied with it. And I think that encapsulates for a lot of people, their experience of proof and evidence. It's a fact and you have to take it as given, but there's actually quite a big bridge often to really understanding why it's true and feeling convinced by it.Eric Topol (04:41):Yeah, I think it's a fabulous example because I think everyone would naturally assume it's 50-50 and it isn't. And I think that gets us to the topic at hand. What I love, there's many things I love about this book. One is that you don't just get into science and medicine, but you cut across all the domains, law, mathematics, AI. So it's a very comprehensive sweep of everything about proof and truth, and it couldn't come at a better time as we'll get into. Maybe just starting off with math, the term I love mathematical monsters. Can you tell us a little bit more about that?Adam Kucharski (05:25):Yeah, this was a fascinating situation that emerged in the late 19th century where a lot of math's, certainly in Europe had been derived from geometry because a lot of the ancient Greek influence on how we shaped things and then Newton and his work on rates of change and calculus, it was really the natural world that provided a lot of inspiration, these kind of tangible objects, tangible movements. And as mathematicians started to build out the theory around rates of change and how we tackle these kinds of situations, they sometimes took that intuition a bit too seriously. And there was some theorems that they said were intuitively obvious, some of these French mathematicians. And so, one for example is this idea of you how things change smoothly over time and how you do those calculations. But what happened was some mathematicians came along and showed that when you have things that can be infinitely small, that intuition didn't necessarily hold in the same way.Adam Kucharski (06:26):And they came up with these examples that broke a lot of these theorems and a lot of the establishments at the time called these things monsters. They called them these aberrations against common sense and this idea that if Newton had known about them, he never would've done all of his discovery because they're just nuisances and we just need to get rid of them. And there's this real tension at the core of mathematics in the late 1800s where some people just wanted to disregard this and say, look, it works for most of the time, that's good enough. And then others really weren't happy with this quite vague logic. They wanted to put it on much sturdier ground. And what was remarkable actually is if you trace this then into the 20th century, a lot of these monsters and these particularly in some cases functions which could almost move constantly, this constant motion rather than our intuitive concept of movement as something that's smooth, if you drop an apple, it accelerates at a very smooth rate, would become foundational in our understanding of things like probability, Einstein's work on atomic theory. A lot of these concepts where geometry breaks down would be really important in relativity. So actually, these things that we thought were monsters actually were all around us all the time, and science couldn't advance without them. So I think it's just this remarkable example of this tension within a field that supposedly concrete and the things that were going to be shunned actually turn out to be quite important.Eric Topol (07:53):It's great how you convey how nature isn't so neat and tidy and things like Brownian motion, understanding that, I mean, just so many things that I think fit into that general category. In the legal, we won't get into too much because that's not so much the audience of Ground Truths, but the classic things about innocent and until proven guilty and proof beyond reasonable doubt, I mean these are obviously really important parts of that overall sense of proof and truth. We're going to get into one thing I'm fascinated about related to that subsequently and then in science. So before we get into the different types of proof, obviously the pandemic is still fresh in our minds and we're an endemic with Covid now, and there are so many things we got wrong along the way of uncertainty and didn't convey that science isn't always evolving search for what is the truth. There's plenty no shortage of uncertainty at any moment. So can you recap some of the, you did so much work during the pandemic and obviously some of it's in the book. What were some of the major things that you took out of proof and truth from the pandemic?Adam Kucharski (09:14):I think it was almost this story of two hearts because on the one hand, science was the thing that got us where we are today. The reason that so much normality could resume and so much risk was reduced was development of vaccines and the understanding of treatments and the understanding of variants as they came to their characteristics. So it was kind of this amazing opportunity to see this happen faster than it ever happened in history. And I think ever in science, it certainly shifted a lot of my thinking about what's possible and even how we should think about these kinds of problems. But also on the other hand, I think where people might have been more familiar with seeing science progress a bit more slowly and reach consensus around some of these health issues, having that emerge very rapidly can present challenges even we found with some of the work we did on Alpha and then the Delta variants, and it was the early quantification of these.Adam Kucharski (10:08):So really the big question is, is this thing more transmissible? Because at the time countries were thinking about control measures, thinking about relaxing things, and you've got this just enormous social economic health decision-making based around essentially is it a lot more spreadable or is it not? And you only had these fragments of evidence. So I think for me, that was really an illustration of the sharp end. And I think what we ended up doing with some of those was rather than arguing over a precise number, something like Delta, instead we kind of looked at, well, what's the range that matters? So in the sense of arguing over whether it's 40% or 50% or 30% more transmissible is perhaps less important than being, it's substantially more transmissible and it's going to start going up. Is it going to go up extremely fast or just very fast?Adam Kucharski (10:59):That's still a very useful conclusion. I think what often created some of the more challenges, I think the things that on reflection people looking back pick up on are where there was probably overstated certainty. We saw that around some of the airborne spread, for example, stated as a fact by in some cases some organizations, I think in some situations as well, governments had a constraint and presented it as scientific. So the UK, for example, would say testing isn't useful. And what was happening at the time was there wasn't enough tests. So it was more a case of they can't test at that volume. But I think blowing between what the science was saying and what the decision-making, and I think also one thing we found in the UK was we made a lot of the epidemiological evidence available. I think that was really, I think something that was important.Adam Kucharski (11:51):I found it a lot easier to communicate if talking to the media to be able to say, look, this is the paper that's out, this is what it means, this is the evidence. I always found it quite uncomfortable having to communicate things where you knew there were reports behind the scenes, but you couldn't actually articulate. But I think what that did is it created this impression that particularly epidemiology was driving the decision-making a lot more than it perhaps was in reality because so much of that was being made public and a lot more of the evidence around education or economics was being done behind the scenes. I think that created this kind of asymmetry in public perception about how that was feeding in. And so, I think there was always that, and it happens, it is really hard as well as a scientist when you've got journalists asking you how to run the country to work out those steps of am I describing the evidence behind what we're seeing? Am I describing the evidence about different interventions or am I proposing to some extent my value system on what we do? And I think all of that in very intense times can be very easy to get blurred together in public communication. I think we saw a few examples of that where things were being the follow the science on policy type angle where actually once you get into what you're prioritizing within a society, quite rightly, you've got other things beyond just the epidemiology driving that.Eric Topol (13:09):Yeah, I mean that term that you just use follow the science is such an important term because it tells us about the dynamic aspect. It isn't just a snapshot, it's constantly being revised. But during the pandemic we had things like the six-foot rule that was never supported by data, but yet still today, if I walk around my hospital and there's still the footprints of the six-foot rule and not paying attention to the fact that this was airborne and took years before some of these things were accepted. The flatten the curve stuff with lockdowns, which I never was supportive of that, but perhaps at the worst point, the idea that hospitals would get overrun was an issue, but it got carried away with school shutdowns for prolonged periods and in some parts of the world, especially very stringent lockdowns. But anyway, we learned a lot.Eric Topol (14:10):But perhaps one of the greatest lessons is that people's expectations about science is that it's absolute and somehow you have this truth that's not there. I mean, it's getting revised. It's kind of on the job training, it's on this case on the pandemic revision. But very interesting. And that gets us to, I think the next topic, which I think is a fundamental part of the book distributed throughout the book, which is the different types of proof in biomedicine and of course across all these domains. And so, you take us through things like randomized trials, p-values, 95 percent confidence intervals, counterfactuals, causation and correlation, peer review, the works, which is great because a lot of people have misconceptions of these things. So for example, randomized trials, which is the temple of the randomized trials, they're not as great as a lot of people think, yes, they can help us establish cause and effect, but they're skewed because of the people who come into the trial. So they may not at all be a representative sample. What are your thoughts about over deference to randomized trials?Adam Kucharski (15:31):Yeah, I think that the story of how we rank evidence in medicines a fascinating one. I mean even just how long it took for people to think about these elements of randomization. Fundamentally, what we're trying to do when we have evidence here in medicine or science is prevent ourselves from confusing randomness for a signal. I mean, that's fundamentally, we don't want to mistake something, we think it's going on and it's not. And the challenge, particularly with any intervention is you only get to see one version of reality. You can't give someone a drug, follow them, rewind history, not give them the drug and then follow them again. So one of the things that essentially randomization allows us to do is, if you have two groups, one that's been randomized, one that hasn't on average, the difference in outcomes between those groups is going to be down to the treatment effect.Adam Kucharski (16:20):So it doesn't necessarily mean in reality that'd be the case, but on average that's the expectation that you'd have. And it's kind of interesting actually that the first modern randomized control trial (RCT) in medicine in 1947, this is for TB and streptomycin. The randomization element actually, it wasn't so much statistical as behavioral, that if you have people coming to hospital, you could to some extent just say, we'll just alternate. We're not going to randomize. We're just going to first patient we'll say is a control, second patient a treatment. But what they found in a lot of previous studies was doctors have bias. Maybe that patient looks a little bit ill or that one maybe is on borderline for eligibility. And often you got these quite striking imbalances when you allowed it for human judgment. So it was really about shielding against those behavioral elements. But I think there's a few situations, it's a really powerful tool for a lot of these questions, but as you mentioned, one is this issue of you have the population you study on and then perhaps in reality how that translates elsewhere.Adam Kucharski (17:17):And we see, I mean things like flu vaccines are a good example, which are very dependent on immunity and evolution and what goes on in different populations. Sometimes you've had a result on a vaccine in one place and then the effectiveness doesn't translate in the same way to somewhere else. I think the other really important thing to bear in mind is, as I said, it's the averaging that you're getting an average effect between two different groups. And I think we see certainly a lot of development around things like personalized medicine where actually you're much more interested in the outcome for the individual. And so, what a trial can give you evidence is on average across a group, this is the effect that I can expect this intervention to have. But we've now seen more of the emergence things like N=1 studies where you can actually over the same individual, particularly for chronic conditions, look at those kind of interventions.Adam Kucharski (18:05):And also there's just these extreme examples where you're ethically not going to run a trial, there's never been a trial of whether it's a good idea to have intensive care units in hospitals or there's a lot of these kind of historical treatments which are just so overwhelmingly effective that we're not going to run trial. So almost this hierarchy over time, you can see it getting shifted because actually you do have these situations where other forms of evidence can get you either closer to what you need or just more feasibly an answer where it's just not ethical or practical to do an RCT.Eric Topol (18:37):And that brings us to the natural experiments I just wrote about recently, the one with shingles, which there's two big natural experiments to suggest that shingles vaccine might reduce the risk of Alzheimer's, an added benefit beyond the shingles that was not anticipated. Your thoughts about natural experiments, because here you're getting a much different type of population assessment, again, not at the individual level, but not necessarily restricted by some potentially skewed enrollment criteria.Adam Kucharski (19:14):I think this is as emerged as a really valuable tool. It's kind of interesting, in the book you're talking to economists like Josh Angrist, that a lot of these ideas emerge in epidemiology, but I think were really then taken up by economists, particularly as they wanted to add more credibility to a lot of these policy questions. And ultimately, it comes down to this issue that for a lot of problems, we can't necessarily intervene and randomize, but there might be a situation that's done it to some extent for us, so the classic example is the Vietnam draft where it was kind of random birthdays with drawn out of lottery. And so, there's been a lot of studies subsequently about the effect of serving in the military on different subsequent lifetime outcomes because broadly those people have been randomized. It was for a different reason. But you've got that element of randomization driving that.Adam Kucharski (20:02):And so again, with some of the recent shingles data and other studies, you might have a situation for example, where there's been an intervention that's somewhat arbitrary in terms of time. It's a cutoff on a birth date, for example. And under certain assumptions you could think, well, actually there's no real reason for the person on this day and this day to be fundamentally different. I mean, perhaps there might be effects of cohorts if it's school years or this sort of thing. But generally, this isn't the same as having people who are very, very different ages and very different characteristics. It's just nature, or in this case, just a policy intervention for a different reason has given you that randomization, which allows you or pseudo randomization, which allows you to then look at something about the effect of an intervention that you wouldn't as reliably if you were just digging into the data of yes, no who's received a vaccine.Eric Topol (20:52):Yeah, no, I think it's really valuable. And now I think increasingly given priority, if you can find these natural experiments and they're not always so abundant to use to extrapolate from, but when they are, they're phenomenal. The causation correlation is so big. The issue there, I mean Judea Pearl's, the Book of Why, and you give so many great examples throughout the book in Proof. I wonder if you could comment that on that a bit more because this is where associations are confused somehow or other with a direct effect. And we unfortunately make these jumps all too frequently. Perhaps it's the most common problem that's occurring in the way we interpret medical research data.Adam Kucharski (21:52):Yeah, I think it's an issue that I think a lot of people get drilled into in their training just because a correlation between things doesn't mean that that thing causes this thing. But it really struck me as I talked to people, researching the book, in practice in research, there's actually a bit more to it in how it's played out. So first of all, if there's a correlation between things, it doesn't tell you much generally that's useful for intervention. If two things are correlated, it doesn't mean that changing that thing's going to have an effect on that thing. There might be something that's influencing both of them. If you have more ice cream sales, it will lead to more heat stroke cases. It doesn't mean that changing ice cream sales is going to have that effect, but it does allow you to make predictions potentially because if you can identify consistent patterns, you can say, okay, if this thing going up, I'm going to make a prediction that this thing's going up.Adam Kucharski (22:37):So one thing I found quite striking, actually talking to research in different fields is how many fields choose to focus on prediction because it kind of avoids having to deal with this cause and effect problem. And even in fields like psychology, it was kind of interesting that there's a lot of focus on predicting things like relationship outcomes, but actually for people, you don't want a prediction about your relationship. You want to know, well, how can I do something about it? You don't just want someone to sell you your relationship's going to go downhill. So there's almost part of the challenge is people just got stuck on prediction because it's an easier field of work, whereas actually some of those problems will involve intervention. I think the other thing that really stood out for me is in epidemiology and a lot of other fields, rightly, people are very cautious to not get that mixed up.Adam Kucharski (23:24):They don't want to mix up correlations or associations with causation, but you've kind of got this weird situation where a lot of papers go out of their way to not use causal language and say it's an association, it's just an association. It's just an association. You can't say anything about causality. And then the end of the paper, they'll say, well, we should think about introducing more of this thing or restricting this thing. So really the whole paper and its purpose is framed around a causal intervention, but it's extremely careful throughout the paper to not frame it as a causal claim. So I think we almost by skirting that too much, we actually avoid the problems that people sometimes care about. And I think a lot of the nice work that's been going on in causal inference is trying to get people to confront this more head on rather than say, okay, you can just stay in this prediction world and that's fine. And then just later maybe make a policy suggestion off the back of it.Eric Topol (24:20):Yeah, I think this is cause and effect is a very alluring concept to support proof as you so nicely go through in the book. But of course, one of the things that we use to help us is the biological mechanism. So here you have, let's say for example, you're trying to get a new drug approved by the Food and Drug Administration (FDA), and the request is, well, we want two trials, randomized trials, independent. We want to have p-values that are significant, and we want to know the biological mechanism ideally with the dose response of the drug. But there are many drugs as you review that have no biological mechanism established. And even when the tobacco problems were mounting, the actual mechanism of how tobacco use caused cancer wasn't known. So how important is the biological mechanism, especially now that we're well into the AI world where explainability is demanded. And so, we don't know the mechanism, but we also don't know the mechanism and lots of things in medicine too, like anesthetics and even things as simple as aspirin, how it works and many others. So how do we deal with this quest for the biological mechanism?Adam Kucharski (25:42):I think that's a really good point. It shows almost a lot of the transition I think we're going through currently. I think particularly for things like smoking cancer where it's very hard to run a trial. You can't make people randomly take up smoking. Having those additional pieces of evidence, whether it's an analogy with a similar carcinogen, whether it's a biological mechanism, can help almost give you more supports for that argument that there's a cause and effect going on. But I think what I found quite striking, and I realized actually that it's something that had kind of bothered me a bit and I'd be interested to hear whether it bothers you, but with the emergence of AI, it's almost a bit of the loss of scientific satisfaction. I think you grow up with learning about how the world works and why this is doing what it's doing.Adam Kucharski (26:26):And I talked for example of some of the people involved with AlphaFold and some of the subsequent work in installing those predictions about structures. And they'd almost made peace with it, which I found interesting because I think they started off being a bit uncomfortable with like, yeah, you've got these remarkable AI models making these predictions, but we don't understand still biologically what's happening here. But I think they're just settled in saying, well, biology is really complex on some of these problems, and if we can have a tool that can give us this extremely valuable information, maybe that's okay. And it was just interesting that they'd really kind of gone through that kind process, which I think a lot of people are still grappling with and that almost that discomfort of using AI and what's going to convince you that that's a useful reliable prediction whether it's something like predicting protein folding or getting in a self-driving car. What's the evidence you need to convince you that's reliable?Eric Topol (27:26):Yeah, no, I'm so glad you brought that up because when Demis Hassabis and John Jumper won the Nobel Prize, the point I made was maybe there should be an asterisk with AI because they don't know how it works. I mean, they had all the rich data from the protein data bank, and they got the transformer model to do it for 200 million protein structure prediction, but they still to this day don't fully understand how the model really was working. So it reinforces what you're just saying. And of course, it cuts across so many types of AI. It's just that we tend to hold different standards in medicine not realizing that there's lots of lack of explainability for routine medical treatments today. Now one of the things that I found fascinating in your book, because there's different levels of proof, different types of proof, but solid logical systems.Eric Topol (28:26):And on page 60 of the book, especially pertinent to the US right now, there is a bit about Kurt Gödel and what he did there was he basically, there was a question about dictatorship in the US could it ever occur? And Gödel says, “oh, yes, I can prove it.” And he's using the constitution itself to prove it, which I found fascinating because of course we're seeing that emerge right now. Can you give us a little bit more about this, because this is fascinating about the Fifth Amendment, and I mean I never thought that the Constitution would allow for a dictatorship to emerge.Adam Kucharski (29:23):And this was a fascinating story, Kurt Gödel who is one of the greatest logical minds of the 20th century and did a lot of work, particularly in the early 20th century around system of rules, particularly things like mathematics and whether they can ever be really fully satisfying. So particularly in mathematics, he showed that there were this problem that is very hard to have a set of rules for something like arithmetic that was both complete and covered every situation, but also had no contradictions. And I think a lot of countries, if you go back, things like Napoleonic code and these attempts to almost write down every possible legal situation that could be imaginable, always just ascended into either they needed amendments or they had contradictions. I think Gödel's work really summed it up, and there's a story, this is in the late forties when he had his citizenship interview and Einstein and Oskar Morgenstern went along as witnesses for him.Adam Kucharski (30:17):And it's always told as kind of a lighthearted story as this logical mind, this academic just saying something silly in front of the judge. And actually, to my own admission, I've in the past given talks and mentioned it in this slightly kind of lighthearted way, but for the book I got talking to a few people who'd taken it more seriously. I realized actually he's this extremely logically focused mind at the time, and maybe there should have been something more to it. And people who have kind of dug more into possibilities was saying, well, what could he have spotted that bothered him? And a lot of his work that he did about consistency in mass was around particularly self-referential statements. So if I say this sentence is false, it's self-referential and if it is false, then it's true, but if it's true, then it's false and you get this kind of weird self-referential contradictions.Adam Kucharski (31:13):And so, one of the theories about Gödel was that in the Constitution, it wasn't that there was a kind of rule for someone can become a dictator, but rather people can use the mechanisms within the Constitution to make it easier to make further amendments. And he kind of downward cycle of amendment that he had seen happening in Europe and the run up to the war, and again, because this is never fully documented exactly what he thought, but it's one of the theories that it wouldn't just be outright that it would just be this cycle process of weakening and weakening and weakening and making it easier to add. And actually, when I wrote that, it was all the earlier bits of the book that I drafted, I did sort of debate whether including it I thought, is this actually just a bit in the weeds of American history? And here we are. Yeah, it's remarkable.Eric Topol (32:00):Yeah, yeah. No, I mean I found, it struck me when I was reading this because here back in 1947, there was somebody predicting that this could happen based on some, if you want to call it loopholes if you will, or the ability to change things, even though you would've thought otherwise that there wasn't any possible capability for that to happen. Now, one of the things I thought was a bit contradictory is two parts here. One is from Angus Deaton, he wrote, “Gold standard thinking is magical thinking.” And then the other is what you basically are concluding in many respects. “To navigate proof, we must reach into a thicket of errors and biases. We must confront monsters and embrace uncertainty, balancing — and rebalancing —our beliefs. We must seek out every useful fragment of data, gather every relevant tool, searching wider and climbing further. Finding the good foundations among the bad. Dodging dogma and falsehoods. Questioning. Measuring. Triangulating. Convincing. Then perhaps, just perhaps, we'll reach the truth in time.” So here you have on the one hand your search for the truth, proof, which I think that little paragraph says it all. In many respects, it sums up somewhat to the work that you review here and on the other you have this Nobel laureate saying, you don't have to go to extremes here. The enemy of good is perfect, perhaps. I mean, how do you reconcile this sense that you shouldn't go so far? Don't search for absolute perfection of proof.Adam Kucharski (33:58):Yeah, I think that encapsulates a lot of what the book is about, is that search for certainty and how far do you have to go. I think one of the things, there's a lot of interesting discussion, some fascinating papers around at what point do you use these studies? What are their flaws? But I think one of the things that does stand out is across fields, across science, medicine, even if you going to cover law, AI, having these kind of cookie cutter, this is the definitive way of doing it. And if you just follow this simple rule, if you do your p-value, you'll get there and you'll be fine. And I think that's where a lot of the danger is. And I think that's what we've seen over time. Certain science people chasing certain targets and all the behaviors that come around that or in certain situations disregarding valuable evidence because you've got this kind of gold standard and nothing else will do.Adam Kucharski (34:56):And I think particularly in a crisis, it's very dangerous to have that because you might have a low level of evidence that demands a certain action and you almost bias yourself towards inaction if you have these kind of very simple thresholds. So I think for me, across all of these stories and across the whole book, I mean William Gosset who did a lot of pioneering work on statistical experiments at Guinness in the early 20th century, he had this nice question he sort of framed is, how much do we lose? And if we're thinking about the problems, there's always more studies we can do, there's always more confidence we can have, but whether it's a patient we want to treat or crisis we need to deal with, we need to work out actually getting that level of proof that's really appropriate for where we are currently.Eric Topol (35:49):I think exceptionally important that there's this kind of spectrum or continuum in following science and search for truth and that distinction, I think really nails it. Now, one of the things that's unique in the book is you don't just go through all the different types of how you would get to proof, but you also talk about how the evidence is acted on. And for example, you quote, “they spent a lot of time misinforming themselves.” This is the whole idea of taking data and torturing it or using it, dredging it however way you want to support either conspiracy theories or alternative facts. Basically, manipulating sometimes even emasculating what evidence and data we have. And one of the sentences, or I guess this is from Sir Francis Bacon, “truth is a daughter of time”, but the added part is not authority. So here we have our president here that repeats things that are wrong, fabricated or wrong, and he keeps repeating to the point that people believe it's true. But on the other hand, you could say truth is a daughter of time because you like to not accept any truth immediately. You like to see it get replicated and further supported, backed up. So in that one sentence, truth is a daughter of time not authority, there's the whole ball of wax here. Can you take us through that? Because I just think that people don't understand that truth being tested over time, but also manipulated by its repetition. This is a part of the big problem that we live in right now.Adam Kucharski (37:51):And I think it's something that writing the book and actually just reflecting on it subsequently has made me think about a lot in just how people approach these kinds of problems. I think that there's an idea that conspiracy theorists are just lazy and have maybe just fallen for a random thing, but talking to people, you really think about these things a lot more in the field. And actually, the more I've ended up engaging with people who believe things that are just outright unevidenced around vaccines, around health issues, they often have this mountain of papers and data to hand and a lot of it, often they will be peer reviewed papers. It won't necessarily be supporting the point that they think it's supports.Adam Kucharski (38:35):But it's not something that you can just say everything you're saying is false, that there's actually often a lot of things that have been put together and it's just that leap to that conclusion. I think you also see a lot of scientific language borrowed. So I gave a talker early this year and it got posted on YouTube. It had conspiracy theories it, and there was a lot of conspiracy theory supporters who piled in the comments and one of the points they made is skepticism is good. It's the kind of law society, take no one's word for it, you need this. We are the ones that are kind of doing science and people who just assume that science is settled are in the wrong. And again, you also mentioned that repetition. There's this phenomenon, it's the illusory truth problem that if you repeatedly tell someone someone's something's false, it'll increase their belief in it even if it's something quite outrageous.Adam Kucharski (39:27):And that mimics that scientific repetition because people kind of say, okay, well if I've heard it again and again, it's almost like if you tweak these as mini experiments, I'm just accumulating evidence that this thing is true. So it made me think a lot about how you've got essentially a lot of mimicry of the scientific method, amount of data and how you present it and this kind of skepticism being good, but I think a lot of it comes down to as well as just looking at theological flaws, but also ability to be wrong in not actually seeking out things that confirm. I think all of us, it's something that I've certainly tried to do a lot working on emergencies, and one of the scientific advisory groups that I worked on almost it became a catchphrase whenever someone presented something, they finished by saying, tell me why I'm wrong.Adam Kucharski (40:14):And if you've got a variant that's more transmissible, I don't want to be right about that really. And it is something that is quite hard to do and I found it is particularly for something that's quite high pressure, trying to get a policymaker or someone to write even just non-publicly by themselves, write down what you think's going to happen or write down what would convince you that you are wrong about something. I think particularly on contentious issues where someone's got perhaps a lot of public persona wrapped up in something that's really hard to do, but I think it's those kind of elements that distinguish between getting sucked into a conspiracy theory and really seeking out evidence that supports it and trying to just get your theory stronger and stronger and actually seeking out things that might overturn your belief about the world. And it's often those things that we don't want overturned. I think those are the views that we all have politically or in other ways, and that's often where the problems lie.Eric Topol (41:11):Yeah, I think this is perhaps one of, if not the most essential part here is that to try to deal with the different views. We have biases as you emphasized throughout, but if you can use these different types of proof to have a sound discussion, conversation, refutation whereby you don't summarily dismiss another view which may be skewed and maybe spurious or just absolutely wrong, maybe fabricated whatever, but did you can engage and say, here's why these are my proof points, or this is why there's some extent of certainty you can have regarding this view of the data. I think this is so fundamental because unfortunately as we saw during the pandemic, the strident minority, which were the anti-science, anti-vaxxers, they were summarily dismissed as being kooks and adopting conspiracy theories without the right engagement and the right debates. And I think this might've helped along the way, no less the fact that a lot of scientists didn't really want to engage in the first place and adopt this methodical proof that you've advocated in the book so many different ways to support a hypothesis or an assertion. Now, we've covered a lot here, Adam. Have I missed some central parts of the book and the effort because it's really quite extraordinary. I know it's your third book, but it's certainly a standout and it certainly it's a standout not just for your books, but books on this topic.Adam Kucharski (43:13):Thanks. And it's much appreciated. It was not an easy book to write. I think at times, I kind of wondered if I should have taken on the topic and I think a core thing, your last point speaks to that. I think a core thing is that gap often between what convinces us and what convinces someone else. I think it's often very tempting as a scientist to say the evidence is clear or the science has proved this. But even on something like the vaccines, you do get the loud minority who perhaps think they're putting microchips in people and outlandish views, but you actually get a lot more people who might just have some skepticism of pharmaceutical companies or they might have, my wife was pregnant actually at the time during Covid and we waited up because there wasn't much data on pregnancy and the vaccine. And I think it's just finding what is convincing. Is it having more studies from other countries? Is it understanding more about the biology? Is it understanding how you evaluate some of those safety signals? And I think that's just really important to not just think what convinces us and it's going to be obvious to other people, but actually think where are they coming from? Because ultimately having proof isn't that good unless it leads to the action that can make lives better.Eric Topol (44:24):Yeah. Well, look, you've inculcated my mind with this book, Adam, called Proof. Anytime I think of the word proof, I'm going to be thinking about you. So thank you. Thanks for taking the time to have a conversation about your book, your work, and I know we're going to count on you for the astute mathematics and analysis of outbreaks in the future, which we will see unfortunately. We are seeing now, in fact already in this country with measles and whatnot. So thank you and we'll continue to follow your great work.**************************************Thanks for listening, watching or reading this Ground Truths podcast/post.If you found this interesting please share it!That makes the work involved in putting these together especially worthwhile.I'm also appreciative for your subscribing to Ground Truths. All content —its newsletters, analyses, and podcasts—is free, open-access. I'm fortunate to get help from my producer Jessica Nguyen and Sinjun Balabanoff for audio/video tech support to pull these podcasts together for Scripps Research.Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don't hesitate to post comments and give me feedback. Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years.A bit of an update on SUPER AGERSMy book has been selected as a Next Big Idea Club winner for Season 26 by Adam Grant, Malcolm Gladwell, Susan Cain, and Daniel Pink. This club has spotlighted the most groundbreaking nonfiction books for over a decade. As a winning title, my book will be shipped to thousands of thoughtful readers like you, featured alongside a reading guide, a "Book Bite," Next Big Idea Podcast episode as well as a live virtual Q&A with me in the club's vibrant online community. If you're interested in joining the club, here's a promo code SEASON26 for 20% off at the website. SUPER AGERS reached #3 for all books on Amazon this week. This was in part related to the segment on the book on the TODAY SHOW which you can see here. Also at Amazon there is a remarkable sale on the hardcover book for $10.l0 at the moment for up to 4 copies. Not sure how long it will last or what prompted it.The journalist Paul von Zielbauer has a Substack “Aging With Strength” and did an extensive interview with me on the biology of aging and how we can prevent the major age-related diseases. Here's the link. Get full access to Ground Truths at erictopol.substack.com/subscribe

Pitcher List Baseball Podcasts
OTW 220 - Waiver Wire Adds for Sunday June 29; FAAB #15

Pitcher List Baseball Podcasts

Play Episode Listen Later Jun 28, 2025 81:54


On The Wire Adam Howe and Kevin Hasting analyze the FAAB-related news of the week and discuss some players to pick up during Sunday's FAAB run.Chandler Simpson recalled by TB, Kameron Misner optioned to Triple-ALuisangel Acuña, Francisco Alvarez, and Jared Young optioned to Triple-A by the Mets. Mark Vientos returned Friday (DH hitting 6th)Jeimer Candelario designated for assignment by the RedsChase Burns makes MLB debut for CINJake Fraley to IL, Austin Hays activatedTyler Fitzgerald optioned to Triple-A by the GiantsCorbin Carroll to IL, Jake McCarthy recalledDiamondbacks place Ildemaro Vargas on the IL and call up Blaze AlexanderJordan Lawler injured his hamstring, will be shut down for another month in AAABen Brown optioned to Triple-AGriffin Canning left Thursday's game early with ankle injury. Opening for Mets' rotation?Wyatt Langford to IL for TEX, backdated. Expected back in a weekBryce Harper is expected back during next week's homestand. Who will lose out with his return?Power (HR, RBI)Wenceel Perez (33% OC); Andrew Benintendi (98%, 29%); Gary Sanchez (97%, 51%) Speed (R, SB)Zach McKinstry (93%, 48%); Isaac Collins (67%, 6%)Opportunity (AB, AVG)Mike Tauchman (40%, 4%); Lenyn Sosa (25%, 0%); Jake Meyers (98%, 88%)Pitching Volume (Wins, K's)Trevor Rogers (53%, 7%); Charlie Morton (62% OC); Tomoyuki Sugano (93%, 77%); Richard Fitts (37%, 3%); Eric Lauer (49%, 7%); Slade Cecconi (90%, 37%); David Festa (63%, 33%); Simeon Woods-Richardson (16%, 1%); Tyler Anderson (63%, 14%); Emerson Hancock (42%, 4%); Patrick Corbin (72%, 12%); Bryce Elder (58%, 22%); Chase Burns (0%); Andrew Heaney (95%, 50%); Erick Fedde (98%, 59%); Andre Pallante (67%, 3%); Ryne Nelson (97%, 64%); Randy Vasquez (19%, 3%), Stephen Kolek (56%, 15%), Yu Darvish (84%, 15%)Ratios (ERA, WHIP)Yariel Rodriguez; Braydon FisherSavesGrant TaylorWild CardAndrew Painter  Join Our Discord & Support The Show: PL+ | PL Pro - Get 15% off Yearly with code PODCASTProud member of the Pitcher List Fantasy Baseball Podcast Network

IT Privacy and Security Weekly update.
EP 248.5 Deep Dive. No Telly. The IT Privacy and Security Weekly Update for the Week Ending June 24th., 2025

IT Privacy and Security Weekly update.

Play Episode Listen Later Jun 28, 2025 14:51


What are the latest trends in large-scale cyberattacks, and how can individuals help prevent them?Large-scale cyberattacks, especially Distributed Denial of Service (DDoS), are growing in both scale and sophistication. One recent attack hit 7.3 Tbps, unleashing 37.4 TB of junk traffic in 45 seconds. These attacks often harness botnets made up of compromised Internet of Things (IoT) devices—like home routers or cameras—that have default credentials or unpatched software.How to help prevent this:Change default passwords on IoT devicesRegularly update firmwareDisable unused services (e.g., Telnet)Use firewalls and segment your networkHow do smart TVs and other smart devices compromise privacy, and what's being done?Smart devices like TVs and speakers often use Automatic Content Recognition (ACR) to monitor what you're watching and send this data to manufacturers or advertisers—often without clear consent. This data fuels detailed user profiling and cross-device tracking.In response, the UK's Information Commissioner's Office (ICO) now requires manufacturers to ensure transparency, secure data handling, and routine data deletion—or face enforcement. Consumers can protect themselves by disabling ACR (e.g., SyncPlus on Samsung, Live Plus on LG) and reviewing privacy settings.What are the current limitations of LLM-based AI in enterprise settings?A Salesforce-led study found that large language model (LLM) AI agents succeed at only 58% of basic CRM tasks and just 35% of multi-step ones. More concerning, they exhibit poor confidentiality awareness. Prompting helps slightly but often hurts task accuracy. Current benchmarks fail to assess sensitivity to confidential data, raising red flags for enterprise use without rigorous testing.What are the geopolitical implications of AI and cyber operations?AI and cyber tools are shaping geopolitical strategies. The U.S. accuses Chinese AI firm DeepSeek of aiding military intelligence and bypassing export controls. Chinese law further mandates data sharing with its government, raising global privacy concerns. Meanwhile, cyberattacks are weaponized to disrupt infrastructure and spread disinformation—as seen in Iran's state TV hijacking and a $90M crypto exchange hack.How do data brokers threaten personal safety, and what can you do?Data brokers compile and sell personal data—including home addresses—without vetting buyers. This can lead to stalking or worse, as shown in the murder of Rep. Melissa Hortman, allegedly found via a “people search” site.The U.S. lacks federal regulation, but California's "Delete Act" is a step forward. Until broader laws are in place, individuals must manually opt out of data broker sites or hire services to assist in removing their information.How are ransomware groups evolving?Groups like Qilin are getting more professional. Their “Call a Lawyer” service gives affiliates legal guidance to classify stolen data, assess damages, and negotiate ransoms more effectively—maximizing economic pressure on victims. It's a troubling move toward organized, businesslike cybercrime.Why is ACR in smart TVs a privacy issue?ACR continuously scans all video content viewed on your TV—even from HDMI devices—and sends data to third parties. It enables:Tracking without consentData monetization for targeted adsCross-device profilingPotential security risks from unmaintained TV firmwareWhy should you secure IoT devices?Unpatched IoT devices can be infected and used in global botnet attacks. By securing your devices, you're not only protecting yourself but also helping reduce the scale of global cyber threats.

The Good Sight Podcast
Fighting TB With Nutrition

The Good Sight Podcast

Play Episode Listen Later Jun 27, 2025 18:40


Can food heal? When it comes to tuberculosis, the answer is yes.We often think of food as comfort, culture, or even celebration—but what if it could also be medicine? In this episode, we explore the critical yet often overlooked link between nutrition and TB—how what's on the plate can impact recovery, immunity, and even survival.Joining us is Prachi Shukla, Country Director at World Health Partners, who brings her on-ground experience and expertise to this powerful conversation.We cover:• How poor nutrition increases vulnerability to TB• Why food plays a key role in recovery and treatment success• What local, affordable foods support healing• The intersection of poverty, illness, and access to nutrition• How families and frontline workers can take small but meaningful actionsAbout Nutrition Every Day: It is a special podcast series by The Good Sight and Rise Against Hunger India, bringing sharp, grounded insights on health and nutrition. For feedback or to participate, write to us at ⁠contact@thegoodsight.org⁠CreditsHost: Shreya MResearch: Alisha CShow Artwork: Rajnikant SProduced by: The Good SightConcept: The Good Sight & Rise Against Hunger India#NutritionEveryDay #FoodAsMedicine #Tuberculosis #PublicHealth #TheGoodSight #RiseAgainstHungerIndia #HealthForAll

NeuroEdge with Hunter Williams
How I'd Recover from Mold Toxicity with Peptides (Complete Guide)

NeuroEdge with Hunter Williams

Play Episode Listen Later Jun 27, 2025 45:52


Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/

Tecnocast
O crime tem antena própria

Tecnocast

Play Episode Listen Later Jun 25, 2025 39:42


Uma nova ferramenta usada para dar golpes vem aparecendo com mais frequência no Brasil: as estações rádio base falsas. Em resumo, as ERBs bloqueiam o sinal das operadoras e usam a rede 2G para disparar SMSs com phishing.No episódio de hoje a explica melhor como funcionam esses golpes e o que é possível fazer para se proteger. Dá o play e vem com a gente!Mande seu recadoGrupos da Caixa Postal do Tecnocast: Telegram: t.me/caixapostaltecnocast WhatsApp: tbnet.me/caixapostaltecnocast Você pode mandar comentários (inclusive em áudio, vai que você aparece no Tecnocast?), dúvidas, críticas e sugestões. Participe!Se preferir, você pode se comunicar conosco pela Comunidade e através do e-mail tecnocast@tecnoblog.net.Entre também nos Canais do TB no WhatsApp Canal do Tecnoblog Canal do Achados do TB CréditosProdução: Josué de OliveiraEdição e sonorização: Ariel LiborioArte da capa: Vitor Pádua

Going Bracket Racing
Ep 197 - Doug Foley Jr. - 250k talk and NEW IHRA info!

Going Bracket Racing

Play Episode Listen Later Jun 25, 2025 78:16


This week we sat down with Doug Foley Jr. to talk about his recent success at the TB 250k. We then got deep into the newest IHRA news. How are the races going to work? What's the run order? What are Doug's personal thoughts on the series? All this and more in Episode 197 of the Going Bracket Racing Podcast!Email us at GoingBracketRacing@gmail.com to learn how you can support the show!

Pull Hitter Fantasy Baseball
EP 315: Orion Kerkering, Michael Toglia, Giancarlo Stanton- Main Event Week 14 FAAB Recap w/ Dom

Pull Hitter Fantasy Baseball

Play Episode Listen Later Jun 24, 2025 82:08


The boys are back recapping the player movement from the NFBC Main Event Week 14 FAAB. Plus we look at the possible first round of 2026 draftsExcuse the last audio post. Was a problem with the audio. I deleted itClosersKerkering, Halvorsen, Grant TaylorPower Bats - Toglia - did we just pay for his best week?Stanton - only 81% added?House - .304, 13 HR, 42 run, 41 RBI at AAA.Moniak - 4 HR, 9 RBI last week, but lots of LHP upcomingSanchez - Adley on IL, ton of catcher injuries this weekSPs - Sheehan - back to AAA, but for how long?Jacob Lopez - @ DET this week, 2-step @ TB, vs. SF next week.  Is this for real?Catchers - Adley, Moreno, Herrera, Alvarez owners were all looking for catchers this weekPedro PagesJoey BartLuis TorrensVictor CaratiniLesser added catchers - Austin Wynns, Edgar Quero, Liam Hicks, Patrick BaileyStarting Pitchers - finally a good week to stream 2-start SPs, but are you playing with fire?Janson JunkDidier FuentesEric Lauer - 2-stepTrevor Rogers - 8 shutout tonight wtf? 2-stepJ. Wrobleski - 2-stepGustoKolek 2-stepFitts Parker 2- stepBatsIsaac CollinsDavid HamiltonYazJoey OrtizCanzoneCasey Schmitt⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠PullHitter merch is here! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Welcome to the PullHitter Podcast, your destination for actionable resources and tools to grind your way to ultimate fantasy baseball success.Support my work and join the Pull Hitter Patreon:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠-Access to lively Discord with highly active members sharing player evaluations, draft boards and strategies..get a leg up on your league mates!-Player Breakdowns series in audio and video form-Draft recaps from me-additional Launch Angle episodes-additional Guest episodes-ad free listening-Much more!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://patreon.com/user?u=32383693&utm_medium=clipboard_copy&utm_source=copyLink&utm_campaign=creatorshare_creator&utm_content=join_link⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow on twitter: @pullhitterpod ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twitter.com/PullHitterPod⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ @deadpullhitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twitter.com/deadpullhitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Email : pullhitterpodcast@gmail.com Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠pullhitter.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠My link tree with all of my links in one spot:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://linktr.ee/pullhitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Also check out me cohosting the Launch Angle Podcast with Jeff Zimmerman and Rob Silver!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://anchor.fm/robe

Sneaks & Stats
2025 NBA Finals Recap & A Look Ahead

Sneaks & Stats

Play Episode Listen Later Jun 24, 2025 85:19


In this week's episode, the guys recap the NBA Finals, take a look at some big off-season moves that have already taken place, and the sale of the Los Angeles Lakers.Check us out on Instagram: https://www.instagram.com/sneaksandstats/We're also on YouTube: https://www.youtube.com/channel/UChfjqV40wCrqVFIqlfbnt_ABuy a pair for yourself:Nike x Patta Air Max 90 Waves "Cyber" - https://stockx.com/nike-air-max-90-sp-patta-waves-cyberConverse 1908 Naut-1 x Le Fleur - https://www.converse.com/shop/p/converse-1908-naut-1-unisex-low-top-shoe/A16308C.html?dwvar_A16308C_color=cannoli%20cream%2Fstone%20green&dwvar_A16308C_width=standard&styleNo=A16308C&cgid=Converse 1908 Jogger x Le Fleur - https://www.converse.com/shop/p/converse-1908-jogger-unisex-low-top-shoe/A16192MP.html?dwvar_A16192MP_color=quiet%20tide%2Fstarlight%20blue&dwvar_A16192C_width=standardNike KD 18 "New Timeline" - https://www.nike.com/t/kd18-new-timeline-basketball-shoes-sBxXXKpD/HV1993-301Adidas Harden Vol. 9 "Pinky and the Brain" - https://stockx.com/adidas-harden-vol-9-jalen-williams-white-lucid-lime-pinkNike Ja 1 TB - https://www.dickssportinggoods.com/p/nike-ja-1-basketball-shoes-24nikaj1tbblwhtxxmnk/24nikaj1tbblwhtxxmnk?sku=25421997&srsltid=AfmBOoo4DZ9E2jGpGaa-4ieopKCd6fzO7wgp51v4xXn8IFmuZk_82Lq3AEo&gQT=2

RNZ: Our Changing World
New insights from an old vaccine

RNZ: Our Changing World

Play Episode Listen Later Jun 23, 2025 26:34


Since the 1800s, tuberculosis (TB) has been responsible for an estimated 1 billion deaths. In New Zealand today, we don't get many cases of TB, but worldwide it is the leading infectious disease killer. In the early 1900s a TB vaccine was developed. Called the BCG vaccine, it's still used today. While it is the best TB vaccine we have, it's not actually great at preventing TB infection, only providing some protection for the youngest of patients. However, scientists have discovered that the BCG vaccine can boost people's immune systems in other ways. Now researchers at the Malaghan Institute in Wellington are investigating these findings further. Sign up to the Our Changing World monthly newsletter for episode backstories, science analysis and more.Guests:Dr Kerry Hilligan, Malaghan InstituteRebecca Palmer, Malaghan InstituteLearn more:In 2017, Alison Ballance reported on the looming antimicrobial resistance crisis, with drug-resistant TB part of the problem.Other Our Changing World episodes about research at the Malaghan Institute include this 2024 episode on a new way to target rising stomach cancer rates, and this 2022 episode on next-generation cancer therapies.In 2021, Claire Concannon covered mRNA vaccine technology.The What if...? Genomics in Aotearoa series explores the different ways genomics is transforming different sectors, including infectious disease medicine.Go to this episode on rnz.co.nz for more details

Tick Boot Camp
Episode 527: Lyme Disease, SOT Therapy, and Faith: How Austin Shubert Took Back His Life

Tick Boot Camp

Play Episode Listen Later Jun 21, 2025 98:24


In this powerful episode of the Tick Boot Camp Podcast, we welcome Austin Shubert, a 27-year-old outdoorsman, hunter, and field technician from Zebulon, Georgia. He shares his deeply personal and emotional journey from vibrant health to chronic illness and back toward recovery. Raised in the woods, surrounded by ticks since childhood, Austin never imagined that a single tick bite could change his life.

Health Shotzz by Ryan Fernando
The INSANE Transformation of Sunaina Roshan |S3 E8

Health Shotzz by Ryan Fernando

Play Episode Listen Later Jun 21, 2025 77:33


She once woke up to alcohol and ended her day the same way. From battling jaundice, brain TB, and cancer to enduring bariatric surgery, Sunaina Roshan has lived through what most wouldn't survive.But everything changed after one bold decision: healing her gut.In this episode, she reveals how a structured gut reset transformed her energy, immunity, mood—and mindset. It's a raw, no-fluff conversation about reclaiming health, finding hope, and rebuilding your life when all seems lost.If you're stuck in a health rut or looking for a wake-up call, this is your sign.Full episodeImportant links:⁠⁠⁠⁠⁠⁠⁠⁠⁠Ryan Fernando App⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Diet plan ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Blood test⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Cancer screening⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Studies of the podcast⁠⁠⁠⁠⁠Socials:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Link tree⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Website⁠⁠⁠⁠⁠⁠⁠⁠⁠Products to purchase:-⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Collagen ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠1CHAZE 1500g⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠1CHAZE 750g ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Books ⁠⁠⁠⁠⁠Find Sunaina here: Instagram Facebook X LinkedIn Time stamps:00:00 Trailer1:42 – Introduction3:10 – The Power of Mindset4:14 – Mantra for a Strong Mindset5:55 – Sunaina's Inspiration6:30 – Understanding Gut Microbiome Testing12:21 – First Sign of Change14:06 – Why You Crave Junk Food14:30 – The Secret to Newfound Stamina21:16 – Message to Women Battling Cancer22:49 – Advice to a Young Sunaina23:44 – Diet Before Cancer26:07 – The Importance of Fitness30:39 – Liver Health & Wellness33:30 – Wake-Up Call Moment38:01 – Foods That Help the Liver Regenerate39:54 – The Importance of Cell Turnover41:57 – The Food-Mood Connection42:24 – Chamomile Tea & Better Sleep48:18 – Reversing Fatty Liver47:50 – The Role of Discipline52:29 – Sunaina's Daily Routine58:06 – Advice for Women Struggling with Health1:01:55 – Rapid Fire Round1:11:40 – Overcoming Brain TB1:14:50 – Outro

The Naked Scientists Podcast
Titans of Science: Sharon Peacock

The Naked Scientists Podcast

Play Episode Listen Later Jun 17, 2025 30:56


In the final installment of this season of Titans of Science, Chris Smith speaks with Sharon Peacock, one of the UK's leading voices in infectious disease research. She is best known for her work on whole genome sequencing of pathogens such as MRSA and SARS CoV-2, and studies of antimicrobial resistance... Like this podcast? Please help us by supporting the Naked Scientists

Mayo Clinic Talks
Class 5 Tuberculosis Cases

Mayo Clinic Talks

Play Episode Listen Later Jun 17, 2025 31:59


Host: Darryl S. Chutka, M.D. Guest: John W. Wilson, M.D. Tuberculosis remains a significant health concern. Globally, in 2023, an estimated 10 million individuals developed active tuberculosis and over one million died of the disease. In the U.S., just under 10, 000 individuals in the U.S. were diagnosed with TB, representing an increase over 2022. While tuberculosis remains a treatable disease, it's important to suspect and recognize those who may have it. A class 5 tuberculosis case is part of a TB classification system and refers to a suspected tuberculosis infection that requires further investigation. Symptoms may or may not be present and these patients may have an active TB case that could be contagious. This podcast is about class 5 tuberculosis cases, and my guest is infectious disease specialist, John W. Wilson, M.D., from the Mayo Clinic. Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts

BS3 Sports & Music #XSquad
Vince Marrow Bounces

BS3 Sports & Music #XSquad

Play Episode Listen Later Jun 12, 2025 75:59


TB is back. His daughter did her think for Atherton track in year one. Vince Marrow is heading to Louisville. The upcoming football season has us all like, Yikes. NBA Finals and more!Become a supporter of this podcast: https://www.spreaker.com/podcast/cats-talk-wednesday--4693915/support.

Tecnocast
Liquid Glass

Tecnocast

Play Episode Listen Later Jun 12, 2025 84:39


A Apple apresentou o novo design de todos os seus sistemas operacionais na WWDC 2025. Ele foi chamado Liquid Glass e lembra bastante algumas coisas que a gente já viu ali pelos anos 2000.Além disso tivemos novidades grandes no iPadOS, no que diz respeito à multitarefa. Mas fora isso, o evento parece que deixou um pouquinho a desejar.Mande seu recadoGrupos da Caixa Postal do Tecnocast: Telegram: t.me/caixapostaltecnocast WhatsApp: tbnet.me/caixapostaltecnocast Você pode mandar comentários (inclusive em áudio, vai que você aparece no Tecnocast?), dúvidas, críticas e sugestões. Participe!Se preferir, você pode se comunicar conosco pela Comunidade e através do e-mail tecnocast@tecnoblog.net.Entre também nos Canais do TB no WhatsApp Canal do Tecnoblog Canal do Achados do TB CréditosProdução: Josué de OliveiraEdição e sonorização: Ariel LiborioArte da capa: Vitor Pádua

Windows Weekly (MP3)
WW 936: Liquid Aero - Microsoft Build ditches Seattle, Washington

Windows Weekly (MP3)

Play Episode Listen Later Jun 11, 2025 146:45


Get to know Microsoft's latest Patch Tuesday updates and new features in Windows 11, such as improvements to the Start menu, File Explorer, and Copilot integration. They also cover new AI features coming to the Photos app for Copilot+ PCs and updates to the Microsoft Store. The discussion then shifts to developer conferences like Google I/O and Apple's WWDC, with a focus on their respective AI advancements and product strategies. Plus, the controversy surrounding Microsoft's decision to no longer host its Build conference in Seattle. Don't miss the discussion on the evolving role of the iPad as a potential threat to Surface devices due to recent software enhancements! Windows 11 June Patch Tuesday is here! Big changes for Windows 11 versions 22H2, 23H2, and 24H2 New Start menu finally debuts in Dev and Beta - synchronized again for some reason Copilot+ PCs get Relight feature and natural language search in the Photos app The Microsoft Store gets a major update in the Beta channel And Canary is still a thing, no one knows why Developer conference season draws to a close Build: Protests, problems, and more problems Microsoft pulls out of Seattle permanently Google I/O: Stunning array of AI announcements. But Android 16 is on a weird slow boil after a truncated development cycle Apple WWDC: Apple Intelligence? Look, Liquid Glass! Also, some actual advances across its newly unified platforms Look out Surface: The iPad is a real computer now - And it only took 15 years Microsoft, Google, and Apple all played to their strengths Between Windows 11 2xH2, Android 16, and iOS whatever - do the platform makers even know how to ship software anymore? Xbox Microsoft unveils the first Xbox-branded third-party gaming handheld as part of its Xbox Games Showcase 2025 event - a few interesting things there as well - COD: BO7, Gears remake, Gears v.next delayed to 2026 This heavily modified/optimized version of Windows 11 is coming to more gaming handhelds Looking to the future: What if this is literally the model for future Xbox console hardware? What if the next Xbox was a NUC? More Game Pass titles across platforms for the second half of June You can add 4 TB of storage to your Xbox, but it will cost you dearly Apple loses again in Epic v. Apple, Fortnite can stay in the App Store and developers can stop getting robbed by Apple The Nintendo Switch 2 launched this past week and is apparently the best-selling console of all time at launch PS5 controllers to support multiple Bluetooth connections Tips and Picks Tip of the week: Share Feature, image crunching App pick of the week: Dia Browser RunAs Radio this week: The Case for Telemetry with Liz Fong-Jones Brown liquor pick of the week: Glenlossie 26 Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit Sponsors: uscloud.com 1password.com/windowsweekly

All TWiT.tv Shows (MP3)
Windows Weekly 936: Liquid Aero

All TWiT.tv Shows (MP3)

Play Episode Listen Later Jun 11, 2025 146:45 Transcription Available


Get to know Microsoft's latest Patch Tuesday updates and new features in Windows 11, such as improvements to the Start menu, File Explorer, and Copilot integration. They also cover new AI features coming to the Photos app for Copilot+ PCs and updates to the Microsoft Store. The discussion then shifts to developer conferences like Google I/O and Apple's WWDC, with a focus on their respective AI advancements and product strategies. Plus, the controversy surrounding Microsoft's decision to no longer host its Build conference in Seattle. Don't miss the discussion on the evolving role of the iPad as a potential threat to Surface devices due to recent software enhancements! Windows 11 June Patch Tuesday is here! Big changes for Windows 11 versions 22H2, 23H2, and 24H2 New Start menu finally debuts in Dev and Beta - synchronized again for some reason Copilot+ PCs get Relight feature and natural language search in the Photos app The Microsoft Store gets a major update in the Beta channel And Canary is still a thing, no one knows why Developer conference season draws to a close Build: Protests, problems, and more problems Microsoft pulls out of Seattle permanently Google I/O: Stunning array of AI announcements. But Android 16 is on a weird slow boil after a truncated development cycle Apple WWDC: Apple Intelligence? Look, Liquid Glass! Also, some actual advances across its newly unified platforms Look out Surface: The iPad is a real computer now - And it only took 15 years Microsoft, Google, and Apple all played to their strengths Between Windows 11 2xH2, Android 16, and iOS whatever - do the platform makers even know how to ship software anymore? Xbox Microsoft unveils the first Xbox-branded third-party gaming handheld as part of its Xbox Games Showcase 2025 event - a few interesting things there as well - COD: BO7, Gears remake, Gears v.next delayed to 2026 This heavily modified/optimized version of Windows 11 is coming to more gaming handhelds Looking to the future: What if this is literally the model for future Xbox console hardware? What if the next Xbox was a NUC? More Game Pass titles across platforms for the second half of June You can add 4 TB of storage to your Xbox, but it will cost you dearly Apple loses again in Epic v. Apple, Fortnite can stay in the App Store and developers can stop getting robbed by Apple The Nintendo Switch 2 launched this past week and is apparently the best-selling console of all time at launch PS5 controllers to support multiple Bluetooth connections Tips and Picks Tip of the week: Share Feature, image crunching App pick of the week: Dia Browser RunAs Radio this week: The Case for Telemetry with Liz Fong-Jones Brown liquor pick of the week: Glenlossie 26 Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit Sponsors: uscloud.com 1password.com/windowsweekly

Radio Leo (Audio)
Windows Weekly 936: Liquid Aero

Radio Leo (Audio)

Play Episode Listen Later Jun 11, 2025 146:45 Transcription Available


Get to know Microsoft's latest Patch Tuesday updates and new features in Windows 11, such as improvements to the Start menu, File Explorer, and Copilot integration. They also cover new AI features coming to the Photos app for Copilot+ PCs and updates to the Microsoft Store. The discussion then shifts to developer conferences like Google I/O and Apple's WWDC, with a focus on their respective AI advancements and product strategies. Plus, the controversy surrounding Microsoft's decision to no longer host its Build conference in Seattle. Don't miss the discussion on the evolving role of the iPad as a potential threat to Surface devices due to recent software enhancements! Windows 11 June Patch Tuesday is here! Big changes for Windows 11 versions 22H2, 23H2, and 24H2 New Start menu finally debuts in Dev and Beta - synchronized again for some reason Copilot+ PCs get Relight feature and natural language search in the Photos app The Microsoft Store gets a major update in the Beta channel And Canary is still a thing, no one knows why Developer conference season draws to a close Build: Protests, problems, and more problems Microsoft pulls out of Seattle permanently Google I/O: Stunning array of AI announcements. But Android 16 is on a weird slow boil after a truncated development cycle Apple WWDC: Apple Intelligence? Look, Liquid Glass! Also, some actual advances across its newly unified platforms Look out Surface: The iPad is a real computer now - And it only took 15 years Microsoft, Google, and Apple all played to their strengths Between Windows 11 2xH2, Android 16, and iOS whatever - do the platform makers even know how to ship software anymore? Xbox Microsoft unveils the first Xbox-branded third-party gaming handheld as part of its Xbox Games Showcase 2025 event - a few interesting things there as well - COD: BO7, Gears remake, Gears v.next delayed to 2026 This heavily modified/optimized version of Windows 11 is coming to more gaming handhelds Looking to the future: What if this is literally the model for future Xbox console hardware? What if the next Xbox was a NUC? More Game Pass titles across platforms for the second half of June You can add 4 TB of storage to your Xbox, but it will cost you dearly Apple loses again in Epic v. Apple, Fortnite can stay in the App Store and developers can stop getting robbed by Apple The Nintendo Switch 2 launched this past week and is apparently the best-selling console of all time at launch PS5 controllers to support multiple Bluetooth connections Tips and Picks Tip of the week: Share Feature, image crunching App pick of the week: Dia Browser RunAs Radio this week: The Case for Telemetry with Liz Fong-Jones Brown liquor pick of the week: Glenlossie 26 Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit Sponsors: uscloud.com 1password.com/windowsweekly

Windows Weekly (Video HI)
WW 936: Liquid Aero - Microsoft Build ditches Seattle, Washington

Windows Weekly (Video HI)

Play Episode Listen Later Jun 11, 2025 146:44


Get to know Microsoft's latest Patch Tuesday updates and new features in Windows 11, such as improvements to the Start menu, File Explorer, and Copilot integration. They also cover new AI features coming to the Photos app for Copilot+ PCs and updates to the Microsoft Store. The discussion then shifts to developer conferences like Google I/O and Apple's WWDC, with a focus on their respective AI advancements and product strategies. Plus, the controversy surrounding Microsoft's decision to no longer host its Build conference in Seattle. Don't miss the discussion on the evolving role of the iPad as a potential threat to Surface devices due to recent software enhancements! Windows 11 June Patch Tuesday is here! Big changes for Windows 11 versions 22H2, 23H2, and 24H2 New Start menu finally debuts in Dev and Beta - synchronized again for some reason Copilot+ PCs get Relight feature and natural language search in the Photos app The Microsoft Store gets a major update in the Beta channel And Canary is still a thing, no one knows why Developer conference season draws to a close Build: Protests, problems, and more problems Microsoft pulls out of Seattle permanently Google I/O: Stunning array of AI announcements. But Android 16 is on a weird slow boil after a truncated development cycle Apple WWDC: Apple Intelligence? Look, Liquid Glass! Also, some actual advances across its newly unified platforms Look out Surface: The iPad is a real computer now - And it only took 15 years Microsoft, Google, and Apple all played to their strengths Between Windows 11 2xH2, Android 16, and iOS whatever - do the platform makers even know how to ship software anymore? Xbox Microsoft unveils the first Xbox-branded third-party gaming handheld as part of its Xbox Games Showcase 2025 event - a few interesting things there as well - COD: BO7, Gears remake, Gears v.next delayed to 2026 This heavily modified/optimized version of Windows 11 is coming to more gaming handhelds Looking to the future: What if this is literally the model for future Xbox console hardware? What if the next Xbox was a NUC? More Game Pass titles across platforms for the second half of June You can add 4 TB of storage to your Xbox, but it will cost you dearly Apple loses again in Epic v. Apple, Fortnite can stay in the App Store and developers can stop getting robbed by Apple The Nintendo Switch 2 launched this past week and is apparently the best-selling console of all time at launch PS5 controllers to support multiple Bluetooth connections Tips and Picks Tip of the week: Share Feature, image crunching App pick of the week: Dia Browser RunAs Radio this week: The Case for Telemetry with Liz Fong-Jones Brown liquor pick of the week: Glenlossie 26 Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free shows, a members-only Discord, and behind-the-scenes access. Join today: https://twit.tv/clubtwit Sponsors: uscloud.com 1password.com/windowsweekly

Oh Fork It
Transparencias Contraproducentes

Oh Fork It

Play Episode Listen Later Jun 11, 2025 103:11


Episodio 322.En el Emoji Motel hay un problema espacial giroscópico que es apenas el doble de lo que yo tenía en un momento muy desafortunado, porque era un poquito esquizofrénico y era de 1m, en vez de 2m por culpa de un relojón gigantesco que se ve horroroso ¿Fue Shakira o no fue Shakira?

The Real News Podcast
Nora Loreto's news headlines for Tuesday, June 10, 2025

The Real News Podcast

Play Episode Listen Later Jun 10, 2025 6:03


Canadian journalist Nora Loreto reads the latest headlines for Tuesday, June 10, 2025.TRNN has partnered with Loreto to syndicate and share her daily news digest with our audience. Tune in every morning to the TRNN podcast feed to hear the latest important news stories from Canada and worldwide.Find more headlines from Nora at Sandy & Nora Talk Politics podcast feed.Help us continue producing radically independent news and in-depth analysis by following us and becoming a monthly sustainer.Sign up for our newsletterLike us on FacebookFollow us on TwitterDonate to support this podcast

The Grave Talks | Haunted, Paranormal & Supernatural
The Haunts of George Pearis Cemetery, Part One | Grave Talks CLASSIC

The Grave Talks | Haunted, Paranormal & Supernatural

Play Episode Listen Later May 31, 2025 32:32


This is a Grave Talks CLASSIC EPISODE! As the memories of the living fade from one generation to the next, unfortunately, so too do the resting places for their bodies. The George Pearis Cemetery in Virginia seems to be one of those places. Once a prominent resting place for a captain of the Revolutionary War, it now sits overgrown with weeds, trees, and natural elements, slowly taking over a plot of land lined with moss-covered gravestones that time and much of the living world have forgotten. Today, it seems that there may be more activity from the dead inside the stone gates of this cemetery than anyone alive, including TB patients, war fatalities, the ghost of a little boy whose life tragically ended in a hunting rifle accident, and many others. Today, we learn about the ghosts of The George Pearis Cemetery with paranormal investigator Jake Fife. If you enjoy our interviews and conversations about "The Dead," why not listen ad-free? Become a Premium Supporter of The Grave Talks Through Apple Podcasts or Patreon (http://www.patreon.com/thegravetalks) There, you will get: Access to every episode of our show, AD-FREE! Access to every episode of our show before everyone else! Other EXCLUSIVE supporter perks and more!

The Grave Talks | Haunted, Paranormal & Supernatural
The Haunts of George Pearis Cemetery, Part Two | Grave Talks CLASSIC

The Grave Talks | Haunted, Paranormal & Supernatural

Play Episode Listen Later May 31, 2025 14:25


This is a Grave Talks CLASSIC EPISODE! As the memories of the living fade from one generation to the next, unfortunately, so too do the resting places for their bodies. The George Pearis Cemetery in Virginia seems to be one of those places. Once a prominent resting place for a captain of the Revolutionary War, it now sits overgrown with weeds, trees, and natural elements, slowly taking over a plot of land lined with moss-covered gravestones that time and much of the living world have forgotten. Today, it seems that there may be more activity from the dead inside the stone gates of this cemetery than anyone alive, including TB patients, war fatalities, the ghost of a little boy whose life tragically ended in a hunting rifle accident, and many others. Today, we learn about the ghosts of The George Pearis Cemetery with paranormal investigator Jake Fife. This is Part Two of our conversation. If you enjoy our interviews and conversations about "The Dead," why not listen ad-free? Become a Premium Supporter of The Grave Talks Through Apple Podcasts or Patreon (http://www.patreon.com/thegravetalks) There, you will get: Access to every episode of our show, AD-FREE! Access to every episode of our show before everyone else! Other EXCLUSIVE supporter perks and more!

Pitcher List Fantasy Baseball Podcast
OTW 216 - What's News With You?; FAAB #11

Pitcher List Fantasy Baseball Podcast

Play Episode Listen Later May 31, 2025 82:02


On The WireAdam Howe and Kevin Hasting break down all the FAAB related news from the week and shine a spotlight on who may be available to pick up in your weekly FAAB bids. Michael King to IL with scapula injury, slept awkwardly Lane Thomas to IL with right foot fasciitis Jake Mangum returns to TB from the IL and Chandler Simpson gets the boot to AAA to make room; Kyle Gibson signs with TBPIT welcomes back Endy Rodriguez at the expense of Joey Bart hitting the 7-day concussion ILDL Hall reinstated by MIL, Logan Henderson sent downCamilo Doval officially named SF closerCorey Seager returns to TEX; Alejandro Osuna called Wenceel Perez back for DET, while Matt Vierling is gone as quickly as he returned, hitting the IL with shoulder inflammationJordan Lawler got his chance…. And then sent right back down to AAA. CIN option Luis Mey AND trade Alexis Diaz to LAD for minor league pitcher Mike Villani (drafted just last year). Miguel Castro is out for the season with a right knee injury. Who's playing 1B now for CWS? (They just sent down their two other 1B's last week)Mike Trout returns to LAA lineup on Friday, optioning OF Matthew Lugo. LAA also signs Chris Taylor and sends down early-season phenom Kyren ParisMatt Mervis and Ronny Simon expected to be DFA'd by MIA, call up Heriberto Hernandez (OF)  and Jack Winkler (Infield). Xavier Edwards is playing 2B during his rehab assignment.Anthony Santander returns to IL with a left shoulder injury; Bo Bichette held from friday's gameAJ Smith Shawver had torn UCLJackson Jobe to IL with a flexor strainRockies get Thairo Estrada back from IL, call up Sam Hilliard. DFA Nick Martini, send Adael Amador to AAA. They also sign Orlando ArciaMountcastle left Friday's game with right hamstring discomfort, Mayo coming upBetts missing Friday waiting for Xray results on toe; stubbed it on Wednesday Join Our Discord & Support The Show: PL+ | PL Pro - Get 15% off Yearly with code PODCASTProud member of the Pitcher List Fantasy Baseball Podcast Network

Inside the Birds: A Philadelphia Eagles Podcast
The DiCecco Daily: Previewing Eagles OTAs This Week

Inside the Birds: A Philadelphia Eagles Podcast

Play Episode Listen Later May 26, 2025 15:39


TB's Eagles beat reporter Andrew DiCecco gives his insights and observations from covering the Eagles on a daily basis. #philadelphiaeagles #flyeaglesfly #eagles #jalyxhunt #jalenhurts #willshipley #ainiassmithIn this episode, he gives his pre-OTAs forecast for the Eagles going into the offseason camps.