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Un nouvel épisode du Pharmascope est disponible et on s'attaque cette fois au trouble d'usage d'alcool. Dans cette première partie, Nicolas, Isabelle et une nouvelle invitée discutent du dépistage et de l'évaluation de cette maladie sous diagnostiquée, en plus de réviser la prise en charge du sevrage alcoolique. Les objectifs pour cet épisode sont: Procéder au dépistage du trouble d'usage d'alcool Diagnostiquer un trouble d'usage d'alcool Discuter des bénéfices et des désavantages associés aux principaux traitements pharmacologiques du sevrage alcoolique Ressources pertinentes en lien avec l'épisode Lignes directrices canadiennes récentes en trouble d'usage d'alcool Wood E, Bright J, Hsu K, et coll. Canadian guideline for the clinical management of high-risk drinking and alcohol use disorder. CMAJ. 2023 Oct 16;195(40):E1364-E1379. Repères canadiens sur l'alcool et la santé : rapport final. Centre canadien sur les dépendances et l'usage de substances. 2023 Guide canadien sur les risques associés à l'usage d'alcool Coalition canadienne pour la santé mentale des personnes pagées. Lignes directrices sur le trouble lié à l'utilisation de l'alcool chez les personnes âgées. 2023. Guide de l'INESSS sur la prise en charge du trouble d'utilisation d'alcool INESSS. Sevrage d'alcool et prévention des rechutes. 2021. US Preventive Services Task Force; Curry SJ, Krist AH, Owens DK, et coll. Screening and Behavioral Counseling Interventions to Reduce Unhealthy Alcohol Use in Adolescents and Adults: US Preventive Services Task Force Recommendation Statement. JAMA. 2018 Nov 13;320(18):1899-1909. Mitchell AJ, Bird V, Rizzo M, et coll. Accuracy of one or two simple questions to identify alcohol-use disorder in primary care: a meta-analysis. Br J Gen Pract. 2014 Jul;64(624):e408-18. Bush K, Kivlahan DR, McDonell MB, et coll. The AUDIT alcohol consumption questions (AUDIT-C): an effective brief screening test for problem drinking. Ambulatory Care Quality Improvement Project (ACQUIP). Alcohol Use Disorders Identification Test. Arch Intern Med. 1998 Sep 14;158(16):1789-95. Maldonado JR, Sher Y, Das S, et coll. Prospective Validation Study of the Prediction of Alcohol Withdrawal Severity Scale (PAWSS) in Medically Ill Inpatients: A New Scale for the Prediction of Complicated Alcohol Withdrawal Syndrome. Alcohol Alcohol. 2015 Sep;50(5):509-18. Kaner EF, Beyer FR, Muirhead C, et coll. Effectiveness of brief alcohol interventions in primary care populations. Cochrane Database Syst Rev. 2018 Feb 24;2(2):CD004148. Amato L, Minozzi S, Vecchi S, Davoli M. Benzodiazepines for alcohol withdrawal. Cochrane Database Syst Rev. 2010 Mar 17;(3):CD005063. Daeppen JB, Gache P, Landry U, et coll. Symptom-triggered vs fixed-schedule doses of benzodiazepine for alcohol withdrawal: a randomized treatment trial. Arch Intern Med. 2002 May 27;162(10):1117-21. Elholm B, Larsen K, Hornnes N, Zierau F, Becker U. Alcohol withdrawal syndrome: symptom-triggered versus fixed-schedule treatment in an outpatient setting. Alcohol Alcohol. 2011 May-Jun;46(3):318-23. Minozzi S, Amato L, Vecchi S, Davoli M. Anticonvulsants for alcohol withdrawal. Cochrane Database Syst Rev. 2010 Mar 17;(3):CD005064. Airagnes G, Valter R, Ducoutumany G, Vansteene C, Trabut JB, Gorwood P, Dubertret C, Matta J, Charles-Nelson A, Limosin F. Magnesium in the treatment of alcohol withdrawal syndrome: a multicenter randomized controlled trial. Alcohol Alcohol. 2023 May 9;58(3):329-335.
VFW Magazine May/Jun 2025 Part 2: Command Post by Nick Carswell
VFW Magazine May/Jun 2025 Part 13: Final Salute by Nick Carswell
VFW Magazine May/Jun 2025 Part 8: Storming the Hill by Nick Carswell
VFW Magazine May/Jun 2025 Part 15: VFW Members Distribute Flowers of Rememberance by Nick Carswell
VFW Magazine May/Jun 2025 Part 6: Washington Wire by Nick Carswell
VFW Magazine May/Jun 2025 Part 14: Better Health by Nick Carswell
VFW Magazine May/Jun 2025 Part 4: Now Hear This by Nick Carswell
VFW Magazine May/Jun 2025 Part 3: Mail Call by Nick Carswell
VFW Magazine May/Jun 2025 Part 5: Issues Up Front by Nick Carswell
VFW Magazine May/Jun 2025 Part 7: We do this Daily by Nick Carswell
VFW Magazine May/Jun 2025 Part 9: Illinois VFW Posts Serving Community Needs by Nick Carswell
VFW Magazine May/Jun 2025 Part 10: All About Camaraderie by Nick Carswell
VFW Magazine May/Jun 2025 Part 17: Member Benefits by Nick Carswell
VFW Magazine May/Jun 2025 Part 1: Table of Contents by Nick Carswell
VFW Magazine May/Jun 2025 Part 16: Member Corner by Nick Carswell
VFW Magazine May/Jun 2025 Part 11: VFW Convenes in Arch City by Nick Carswell
VFW Magazine May/Jun 2025 Part 12: Victory in Europe Day by Nick Carswell
Popular during the early years of adhesive dentistry, chemical-cure dentin bonding systems have since become less common with the rise of light-curing, but they still serve a purpose when restoring the pulp chambers of endodontically treated teeth. In this episode Dr. David Alleman discusses the polymerization dynamics of chemical-cure and light-cure adhesives and how that impacts their effectiveness in different aspects of a successful adhesive restoration.Article referenced in this episode:Toshifumi Kuroe, Kana Tachibana, Yukinori Tanino, Noriyuki Satoh, Noboru Ohata, Hidehiko Sano, Nobuo Inoue, Angelo A Caputo, Contraction stress of composite resin build-up procedures for pulpless molars. J Adhes Dent. 2003 Spring;5(1):71-7.S Deliperi, D Alleman, D Rudo. Stress-reduced Direct Composites for the Restoration of Structurally Compromised Teeth: Fiber Design According to the "Wallpapering". Oper Dent. 2017 May/Jun;42(3):233-243. doi: 10.2341/15-289-T. TechniqueAt 12:35 Dr. Alleman creates illustrations to demonstrate air inhibition. To view this video, watch the episode on YouTube https://youtu.be/Y1xHishKlOo or search for Six Lessons Approach Podcast.Send us a textLearn more about Dr. Alleman's work at training programs at allemancenter.com/events. Upcoming training programs April 25-26: SLA In-Person Workshop May 12 Biomimetic Mastership Instagram @david.alleman.dds@davey_alleman_dmd@allemancenter.comYouTube@allemancenter
A new year and a new beginning. Special guest co-host Pedro Mendes joins Dr. Chris Labos to answer a viewer question about menopause. Become a supporter of our show today either on Patreon or through PayPal! Thank you! http://www.patreon.com/thebodyofevidence/ https://www.paypal.com/donate?hosted_button_id=9QZET78JZWCZE Email us your questions at thebodyofevidence@gmail.com. Assistant researcher: Aigul Zaripova, MD Editor: Robyn Flynn Theme music: “Fall of the Ocean Queen“ by Joseph Hackl Rod of Asclepius designed by Kamil J. Przybos Chris' book, Does Coffee Cause Cancer?: https://ecwpress.com/products/does-coffee-cause- cancer Obviously, I'm not your doctor (probably). This podcast is not medical advice for you; it is what we call information. References: Geographic variability of menopausal symptoms 1) Nappi RE et al. Global cross-sectional survey of women with vasomotor symptoms associated with menopause: prevalence and quality of life burden. Menopause. 2021 May 24;28(8):875-882. doi: 10.1097/GME.0000000000001793. 2) Nappi RE, et al. Prevalence and quality-of-life burden of vasomotor symptoms associated with menopause: A European cross-sectional survey. Maturitas. 2023 Jan;167:66-74. doi: 10.1016/j.maturitas.2022.09.006. What's the normal duration of symptoms 3) Avis NE, et al. Study of Women's Health Across the Nation. Duration of menopausal vasomotor symptoms over the menopause transition. JAMA Intern Med. 2015 Apr;175(4):531-9. doi: 10.1001/jamainternmed.2014.8063. The Women's Health Initiative (WHI) studies Rossouw JE et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA. 2002 Jul 17;288(3):321-33. doi: 10.1001/jama.288.3.321. Anderson GL et al. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA. 2004 Apr 14;291(14):1701-12. doi: 10.1001/jama.291.14.1701. Decline in HRT after WHI studies Sprague BL, Trentham-Dietz A, Cronin KA. A sustained decline in postmenopausal hormone use: results from the National Health and Nutrition Examination Survey, 1999-2010. Obstet Gynecol. 2012 Sep;120(3):595-603. doi: 10.1097/AOG.0b013e318265df42. Danish Osteoporosis Prevention Study Schierbeck LL metal. Effect of hormone replacement therapy on cardiovascular events in recently postmenopausal women: randomised trial. BMJ. 2012 Oct 9;345:e6409. doi: 10.1136/bmj.e6409. Kronos Early Estrogen Prevention Study (KEEPS) Harman SM, et al. Arterial imaging outcomes and cardiovascular risk factors in recently menopausal women: a randomized trial. Ann Intern Med. 2014 Aug 19;161(4):249-60. doi: 10.7326/M14-0353. Kronos Early Estrogen Prevention Study (KEEPS) Hodis HN et al. Vascular Effects of Early versus Late Postmenopausal Treatment with Estradiol. N Engl J Med. 2016 Mar 31;374(13):1221-31. doi: 10.1056/NEJMoa1505241. Stopping hormonal therapy Berman RS et al. Risk factors associated with women's compliance with estrogen replacement therapy. J Womens Health. 1997 Apr;6(2):219-26. doi: 10.1089/jwh.1997.6.219. Grady D, Sawaya GF. Discontinuation of postmenopausal hormone therapy. Am J Med. 2005 Dec 19;118 Suppl 12B:163-5. doi: 10.1016/j.amjmed.2005.09.051. Tapering vs. abrupt stop or hormonal therapy Haimov-Kochman R et al. Gradual discontinuation of hormone therapy does not prevent the reappearance of climacteric symptoms: a randomized prospective study. Menopause. 2006 May-Jun;13(3):370-6. doi: 10.1097/01.gme.0000186663.36211.c0. PMID: 16735933.
Dr. Trina Augustin, assistant professor of both anesthesiology and perioperative medicine as well as emergency medicine takes us on a deep dive into the care of persons with aortic stenosis. In this chapter, Alex and Venk learn about how to use ultrasound to diagnose AS, the keys to resuscitation, the pathophysiology of this condition, as well as the value of consultative services and the potential interventions that they may unlock for these patients. Kickoff season 4 with this in depth reminder that sometimes the heart has many hidden perils beyond ACS. CONTACTS X - @AlwaysOnEM; @VenkBellamkonda YouTube - @AlwaysOnEM; @VenkBellamkonda Instagram – @AlwaysOnEM; @Venk_like_vancomycin; @ASFinch; @KatrinaJoyAugustin Email - AlwaysOnEM@gmail.com REFERENCES & LINKS Lichtenstein DA, Meziere GA. Relevance of Lung Ultrasound in the Diagnosis of Acute Respiratory Failure. Chest 2008; 134:117-125 Walsh MH, Smyth LM, Desy JR, Fischer EA, Goffi A, Li N, Lee M, St-Pierre J, Ma IWY. Lung Ultrasound: A Comparison of image interpretation accuracy between curvillinear and phased array transducers. Australia J Ultrasound Med, 26:150-156 Alzahrani H, Woo MY, Johnson C, Pageau P, Millington S, Thiruganasambandamoorthy V. Can severe aortic stenosis be identified by emergency physicians when interpreting a simplified two-view echocardiogram obtained by trained echocardiographers? Crit Ultrasound J. 2015 Apr 18;7:5. doi: 10.1186/s13089-015-0022-8. PMID: 25932319; PMCID: PMC4409610. Furukawa A, Abe Y, Morizane A, Miyaji T, Hosogi S, Ito H. Simple echocardiographic scoring in screening aortic stenosis with focused cardiac ultrasonography in the emergency department. J Cardiol. 2021 Jun;77(6):613-619. doi: 10.1016/j.jjcc.2020.12.006. Epub 2020 Dec 29. PMID: 33386216. Lin J, Drapkin J, Likourezos A, Giakoumatos E, Schachter M, Sarkis JP, Moskovits M, Haines L, Dickman E. Emergency physician bedside echocardiographic identification of left ventricular diastolic dysfunction. American Journal of Emergency medicine Ehrman RR, Russell FM, Ansari AH, Margeta B, Clary JM, Christian E, Cosby KS, Bailitz J. Can emergency physicians diagnose and correctly classify diastolic dysfunction using bedside echocardiography? Am J Emerg Med. 2015 Sep;33(9):1178-83. doi: 10.1016/j.ajem.2015.05.013. Epub 2015 May 21. PMID: 26058890.2021;44:20-25 Del Rios M, Colla J, Kotini-Shah P, Briller J, Gerber B, Prendergast H. Emergency physician use of tissue Doppler bedside echocardiography in detecting diastolic dysfunction: an exploratory study. Crit Ultrasound J. 2018 Jan 25;10(1):4. doi: 10.1186/s13089-018-0084-5. PMID: 29372430; PMCID: PMC5785451. Thiele H, Zeymer U, Neumann FJ, Ferenc M, Olbrich HG, Hausleiter J, de Waha A, Richardt G, Hennersdorf M, Empen K, Fuernau G, Desch S, Eitel I, Hambrecht R, Lauer B, Böhm M, Ebelt H, Schneider S, Werdan K, Schuler G; Intraaortic Balloon Pump in cardiogenic shock II (IABP-SHOCK II) trial investigators. Intra-aortic balloon counterpulsation in acute myocardial infarction complicated by cardiogenic shock (IABP-SHOCK II): final 12 month results of a randomised, open-label trial. Lancet. 2013 Nov 16;382(9905):1638-45. doi: 10.1016/S0140-6736(13)61783-3. Epub 2013 Sep 3. PMID: 24011548. Aksoy O, Yousefzai R, Singh D, Agarwal S, O'Brien B, Griffin BP, Kapadia SR, Tuzcu ME, Penn MS, Nissen SE, Menon V. Cardiogenic shock in the setting of severe aortic stenosis: role of intra-aortic balloon pump support. Heart. 2011 May;97(10):838-43. doi: 10.1136/hrt.2010.206367. Epub 2010 Oct 20. PMID: 20962337. Karatolios K, Chatzis G, Luesebrink U, Markus B, Ahrens H, Tousoulis D, Schieffer B. Impella support following emergency percutaneous balloon aortic valvuloplasty in patients with severe aortic valve stenosis and cardiogenic shock. Hellenic J Cardiol. 2019 May-Jun;60(3):178-181. doi: 10.1016/j.hjc.2018.02.008. Epub 2018 Mar 21. PMID: 29571667. Gottlieb M, Long B, Koyfman A. Evaluation and Management of Aortic Stenosis for the Emergency Clinician: An Evidence-Based Review of the Literature. J Emerg Med. 2018 Jul;55(1):34-41. doi: 10.1016/j.jemermed.2018.01.026. Epub 2018 Mar 7. PMID: 29525246.
Ever wondered if a plant could be both a herbal remedy and a controversial subject in addiction medicine? Join us as we uncover the multifaceted nature of Kratom with Dr. Sonia Del Tredici and Dr. John Keenan from the Addiction Medicine Journal Club podcast for a journal club style episode on Kratom. Together, we explore Kratom's historical uses for pain relief and fatigue management and its growing popularity as an aid in opioid withdrawal. This episode promises to give you a thorough understanding of its pharmacological effects, including interactions with opioid receptors and anti-inflammatory benefits.Our conversation shifts to the intriguing trends in Kratom usage across the United States. We dissect three recent studies on Kratom, highlighting Kratom's allure as a perceived safer option for managing anxiety, depression, and pain. Despite its benefits, we don't shy away from discussing its potential for addiction and the demographic reach of its users. This episode challenges listeners to consider whether the overlap between Kratom users and those with other substance use disorders is surprising or expected, urging healthcare providers to adopt open-ended dialogues to address patient needs effectively.In a deep dive into Kratom Use Disorder, our discussion includes a fascinating case series study examining the use of buprenorphine for treatment. We highlight the study's findings on withdrawal management and Kratom metabolite reduction, exploring the effectiveness of buprenorphine in stabilizing patients. With a significant portion of patients remaining in follow-up care, we ponder the subjective effects of using Kratom alongside buprenorphine. Tune in to grasp the complexities of Kratom use and the importance of education and ongoing research, as we prepare for an upcoming interview with an industry professional to continue this enlightening series.Our episode reviews three studies on Kratom to facilitate our discussion. Here are those studies:Smith KE, Dunn KE, Rogers JM, Grundmann O, McCurdy CR, Garcia-Romeu A, Schriefer D, Swogger MT, Epstein DH. Kratom use as more than a "self-treatment". Am J Drug Alcohol Abuse. 2022 Nov 2;48(6):684-694. Hill K, Grundmann O, Smith KE, Stanciu CN. Prevalence of Kratom Use Disorder Among Kratom Consumers. J Addict Med. 2024 May-Jun 01;18(3):306-312. Broyan, V. R., Brar, J. K., Allgaier, Student, T., & Allgaier, J. T. (2022). Long-term buprenorphine treatment for kratom use disorder: A case series. Substance Abuse, 43(1), 763–766. To contact Dr. Grover: ammadeeasy@fastmail.com
In episode 50 we discuss 3 articles about kratom. We are again joined by our friend Dr. Casey Grover from the Addiction Medicine Made Easy Podcast. Smith KE, Dunn KE, Rogers JM, Grundmann O, McCurdy CR, Garcia-Romeu A, Schriefer D, Swogger MT, Epstein DH. Kratom use as more than a "self-treatment". Am J Drug Alcohol Abuse. 2022 Nov 2;48(6):684-694. Hill K, Grundmann O, Smith KE, Stanciu CN. Prevalence of Kratom Use Disorder Among Kratom Consumers. J Addict Med. 2024 May-Jun 01;18(3):306-312. Broyan, V. R., Brar, J. K., Allgaier, Student, T., & Allgaier, J. T. (2022). Long-term buprenorphine treatment for kratom use disorder: A case series. Substance Abuse, 43(1), 763–766. --- This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make your account, take a brief quiz, and claim your credit. To learn more about opportunities in addiction medicine, visit MI CARES. CME: https://micaresed.org/courses/podcast-addiction-medicine-journal-club/ --- Original theme music: composed and performed by Benjamin Kennedy Audio editing: Michael Bonanno Executive producer: Dr. Patrick Beeman A podcast from Ars Longa Media --- This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice. The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group. Email: addictionmedicinejournalclub@gmail.com Facebook: @AddictionMedJC Facebook Group: Addiction Medicine Journal Club Instagram: @AddictionMedJC Threads: @AddictionMedJC YouTube: addictionmedicinejournalclub Twitter/X: @AddictionMedJC Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities.
In this Complex Care Journal Club podcast episode, Dr. Renee Turchi discusses an intervention study to improve emergency preparedness for families with children and youth with special health care needs. She describes the multiple community partners involved in intervention development, key insights gained while conducting the study, and next steps from this work. SPEAKER Renee M. Turchi, MD, MPH, FAAP Professor and Chair of Pediatrics, Pediatrician in Chief St. Christopher's Hospital for Children HOST Emily Goodwin, MD Clinical Associate Professor of Pediatrics, University of Missouri Kansas City School of Medicine Pediatrician, General Academic Pediatrics Beacon Program, Children's Mercy Kansas City DATE Initial publication date: October 7, 2024. JOURNAL ARTICLE Griffin JS, Hipper TJ, Chernak E, Berhane Z, Davis RK, Popek L, Kurapati P, Kim J, Turchi RM. A Virtual Home Preparedness Intervention Centered on Children and Youth With Special Health Care Needs. Acad Pediatr. 2024 Jun 10:S1876-2859(24)00167-0. doi: 10.1016/j.acap.2024.06.002. Epub ahead of print. PMID: 38866363. https://www.academicpedsjnl.net/article/S1876-2859(24)00167-0/fulltext OTHER REFERENCES Hipper TJ, Davis R, Massey PM, Turchi RM, Lubell KM, Pechta LE, Rose DA, Wolkin A, Briseño L, Franks JL, Chernak E. The Disaster Information Needs of Families of Children with Special Healthcare Needs: A Scoping Review. Health Secur. 2018 May/Jun;16(3):178-192. doi: 10.1089/hs.2018.0007. Epub 2018 Jun 8. PMID: 29883200; PMCID: PMC11015856. https://pubmed.ncbi.nlm.nih.gov/29883200/ TRANSCRIPT https://op-docebo-images.s3.amazonaws.com/Transcripts/Preparing+for+Emergencies+Planning+and+Partnerships+with+Families_Turchi_100824.pdf Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user.For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Turchi RM, Goodwin EJ. Preparing for Emergencies: Planning and Partnerships with Families. 10/2024. OPENPediatrics. Online Podcast. https://soundcloud.com/openpediatrics/preparing-for-emergencies-planning-and-partnerships-with-families.
Pour accéder à l'intégralité de ce podcast et écouter chaque semaine un nouvel épisode du Quart d'Heure Véto, c'est très simple, il vous suffit de vous abonner en cliquant sur ce lien : https://m.audiomeans.fr/s/S-yUNSBZSR Notes et références Article : Craven A, Todd-Donato A, Stokol T, Liepman R, Glasberg I, Wilkins P, Luethy D, Wong D, Schoster A, van den Brom-Spierenburg AJ, Tomlinson JE. Clinical findings and outcome predictors for multinodular pulmonary fibrosis in horses: 46 cases (2009-2019). J Vet Intern Med. 2024 May-Jun;38(3):1842-1857. doi: 10.1111/jvim.17084. Epub 2024 Apr 15. PMID: 38619130; PMCID: PMC11099712. Retrouvez toute la synthèse sur la fiche podcast juste ici : https://audmns.com/iPQLQWQ Pour nous suivre : 1. Abonnez-vous à notre chaine pour profiter de l'intégralité des épisodes : Le Quart d'Heure Véto : décrypte et résume en moins de 15 min un article de biblio véto - Sur abonnement uniquement Le Véto du Mois : Partagez le temps d'une interview l'expérience de vétérinaires emblématiques de notre milieu, des rencontres conviviales, comme si nous étions dans votre salon au coin du feu. Podcasts bonus au fil des inspirations... 2. Le Scope Nous partageons avec vous nos dernières découvertes, inspirations, pistes de réflexion, nouveautés… À découvrir et utiliser dès maintenant, TOUT DE SUITE, dans votre quotidien de vétérinaire, de manager, de vie personnelle, de chef d'entreprise… Et tout cela en moins de 5 minutes top chrono un à 2 mardis par mois ! Je souhaite recevoir mon Scope : https://vetmasterclass.com/lescope/ 3. Contactez-nous, suivez-nous et donnez nous votre avis ! Des sujets que vous souhaiteriez approfondir, des références à partager, ou nous faire part de vos feed-backs : Abonnez-vous à notre chaine, donnez nous des étoiles, un commentaire et partagez autour de vous ! Sur notre site : https://vetmasterclass.com/ Sur Facebook : https://www.facebook.com/VmHorse Sur Instagram : https://www.instagram.com/vetmasterclass/ Sur YouTube : https://www.youtube.com/channel/UC18ovcWk9e-mFiTL34OQ03g Sur Linkedin : https://www.linkedin.com/company/vetmasterclass-horse/about/ Belle journée à tous, Et continuez à vivre votre métier avec Passion !
Un nouvel épisode du Pharmascope est disponible et on s'attaque cette fois au trouble d'usage d'alcool. Dans cette première partie, Nicolas, Isabelle et une nouvelle invitée discutent du dépistage et de l'évaluation de cette maladie sous diagnostiquée, en plus de réviser la prise en charge du sevrage alcoolique. Les objectifs pour cet épisode sont: Procéder au dépistage du trouble d'usage d'alcool Diagnostiquer un trouble d'usage d'alcool Discuter des bénéfices et des désavantages associés aux principaux traitements pharmacologiques du sevrage alcoolique Ressources pertinentes en lien avec l'épisode Lignes directrices canadiennes récentes en trouble d'usage d'alcoolWood E, Bright J, Hsu K, et coll. Canadian guideline for the clinical management of high-risk drinking and alcohol use disorder. CMAJ. 2023 Oct 16;195(40):E1364-E1379. Repères canadiens sur l'alcool et la santé : rapport final. Centre canadien sur les dépendances et l'usage de substances. 2023 Guide canadien sur les risques associés à l'usage d'alcoolCoalition canadienne pour la santé mentale des personnes pagées. Lignes directrices sur le trouble lié à l'utilisation de l'alcool chez les personnes âgées. 2023. Guide de l'INESSS sur la prise en charge du trouble d'utilisation d'alcoolINESSS. Sevrage d'alcool et prévention des rechutes. 2021. US Preventive Services Task Force; Curry SJ, Krist AH, Owens DK, et coll. Screening and Behavioral Counseling Interventions to Reduce Unhealthy Alcohol Use in Adolescents and Adults: US Preventive Services Task Force Recommendation Statement. JAMA. 2018 Nov 13;320(18):1899-1909. Mitchell AJ, Bird V, Rizzo M, et coll. Accuracy of one or two simple questions to identify alcohol-use disorder in primary care: a meta-analysis. Br J Gen Pract. 2014 Jul;64(624):e408-18. Bush K, Kivlahan DR, McDonell MB, et coll. The AUDIT alcohol consumption questions (AUDIT-C): an effective brief screening test for problem drinking. Ambulatory Care Quality Improvement Project (ACQUIP). Alcohol Use Disorders Identification Test. Arch Intern Med. 1998 Sep 14;158(16):1789-95. Maldonado JR, Sher Y, Das S, et coll. Prospective Validation Study of the Prediction of Alcohol Withdrawal Severity Scale (PAWSS) in Medically Ill Inpatients: A New Scale for the Prediction of Complicated Alcohol Withdrawal Syndrome. Alcohol Alcohol. 2015 Sep;50(5):509-18. Kaner EF, Beyer FR, Muirhead C, et coll. Effectiveness of brief alcohol interventions in primary care populations. Cochrane Database Syst Rev. 2018 Feb 24;2(2):CD004148. Amato L, Minozzi S, Vecchi S, Davoli M. Benzodiazepines for alcohol withdrawal. Cochrane Database Syst Rev. 2010 Mar 17;(3):CD005063. Daeppen JB, Gache P, Landry U, et coll. Symptom-triggered vs fixed-schedule doses of benzodiazepine for alcohol withdrawal: a randomized treatment trial. Arch Intern Med. 2002 May 27;162(10):1117-21. Elholm B, Larsen K, Hornnes N, Zierau F, Becker U. Alcohol withdrawal syndrome: symptom-triggered versus fixed-schedule treatment in an outpatient setting. Alcohol Alcohol. 2011 May-Jun;46(3):318-23. Minozzi S, Amato L, Vecchi S, Davoli M. Anticonvulsants for alcohol withdrawal. Cochrane Database Syst Rev. 2010 Mar 17;(3):CD005064. Airagnes G, Valter R, Ducoutumany G, Vansteene C, Trabut JB, Gorwood P, Dubertret C, Matta J, Charles-Nelson A, Limosin F. Magnesium in the treatment of alcohol withdrawal syndrome: a multicenter randomized controlled trial. Alcohol Alcohol. 2023 May 9;58(3):329-335.
There continues to be great confusion regarding the impact of hormone therapy on the breast. And despite the known benefits of hormone therapy, and reassuring data regarding the impact of hormone therapy on breast cancer, most clinicians are still reluctant to prescribe it, and most women are reluctant to take it. Even more so if a woman is high risk for breast cancer or has a breast cancer diagnosis. In this episode, I am joined by Dr. Corinne Menn, a board-certified Ob GYN and menopause expert who herself had a breast cancer diagnosis when she was in her 20s. We will be reviewing the latest research on the impact of estrogen on the breast in several different scenarios. PREGNANCY post breast cancer Women who have a BREAST CANCER diagnosis Women with a FAMILY HISTORY of breast cancer Women with a BRCA MUTATION after prophylactic ovary removal The approach to therapy for women with a NEW BREAST CANCER DIAGNOSIS The use of local vaginal estrogen in women with a breast cancer diagnosis that are taking TAMOXIFEN or using an AROMOTASE INHIBITOR If a LOCAL VAGINAL ESTROGEN needs to be used at the lowest dose What to do if your DOCTOR NOT WILLING to prescribe local or systemic estrogen (list of articles to share is below) If a woman with a breast cancer diagnosis can use TESTOSTERONE for libido and other possible benefits Dr. Corrine Menn https://drmenn.com/ @drmennobgyn For more information: Episode 124 All Hormones Are Not Created Equal with Dr. James Simon Episode 65- The Dilemma of Menopause and Breast Cancer Episode 31 The TRUTH About Hormone Therapy: Does it CAUSE or Does it PREVENT Breast Cancer? Episode 28: The BEST approach for BREAST Cancer Screening and Risk Reduction with Dr. Lisa Larkin Dr. Streicher's Inside Information podcast is not intended to replace medical advice and should be used to supplement, not replace, care by your personal health care clinician. Dr. Streicher disclaims liability for any medical outcomes that may occur because of applying methods suggested or discussed in this podcast. Scientific Articles Hormone Therapy and Risk of Breast Cancer Bluming AZ, Hodis HN, Langer RD. 'Tis but a scratch: a critical review of the Women's Health Initiative evidence associating menopausal hormone therapy with the risk of breast cancer. Menopause. 2023 Dec 1;30(12):1241-1245. Bluming AZ. Introduction: Estrogen Reconsidered: Exploring the Evidence for Estrogen's Benefits and Risks. Cancer J. 2022 May-Jun 01;28(3):157-162. Hodis HN, Sarrel PM. Menopausal hormone therapy and breast cancer: what is the evidence from randomized trials? Climacteric 2018;21:521–8. Levy B, Simon JA. A Contemporary View of Menopausal Hormone Therapy. Obstet Gynecol. 2024 Mar 14. Chlebowski RT, Aragaki AK, Pan K, Mortimer JE, Johnson KC, Wactawski-Wende J, LeBoff MS, Lavasani S, Lane D, Nelson RA, Manson JE. Randomized trials of estrogen-alone and breast cancer incidence: a meta-analysis. Breast Cancer Res Treat. 2024 Apr 23. doi: 10.1007/s10549-024-07307-9. Pan K, Lavasani S, Aragaki AK, Chlebowski RT. Estrogen therapy and breast cancer in randomized clinical trials: a narrative review. Menopause. 2022 Sep 1;29(9):1086-1092. Use of Hormone Therapy in Women with a Breast Cancer Diagnosis Bluming A. Hormone replacement therapy after breast cancer: it is time. Cancer J 2022;28:183–90. Bluming AZ. Safety of systemic hormone replacement therapy in breast cancer survivors. Breast Cancer Res Treat. 2022 Feb;191(3):685-686. doi: 10.1007/s10549-021-06479-y. Fahlén M, Fornander T, Johansson H, Johansson U, Rutqvist LE, Wilking N, von Schoultz E. Hormone replacement therapy after breast cancer: 10 year follow up of the Stockholm randomised trial. Eur J Cancer. 2013 Jan;49(1):52-9. Mikkola TS, Savolainen-Peltonen H, Tuomikoski P, Hoti F, Vattulainen P, Gissler M, et al. Reduced risk of breast cancer mortality in women using postmenopausal hormone therapy: a Finnish nationwide comparative study. Menopause 2016;23:1199–203 Hormone Therapy in Women with BRCA Mutation Kotsopoulos J, Gronwald J, Karlan BY, Huzarski T, Tung N, Moller P, Armel S, Lynch HT, Senter L, Eisen A, Singer CF, Foulkes WD, Jacobson MR, Sun P, Lubinski J, Narod SA; Hereditary Breast Cancer Clinical Study Group. Hormone Replacement Therapy After Oophorectomy and Breast Cancer Risk Among BRCA1 Mutation Carriers. JAMA Oncol. 2018 Aug 1;4(8):1059-1065.. Lauren Streicher, MD is a clinical professor of obstetrics and gynecology at Northwestern University's Feinberg School of Medicine, and the founding medical director of the Northwestern Medicine Center for Sexual Medicine and Menopause. She is a certified menopause practitioner of the North American Menopause Society. Sign up to receive DR. STREICHER'S FREE NEWSLETTER Dr. Streicher is the medical correspondent for Chicago's top-rated news program, the WGN Morning News, and has been seen on The Today Show, Good Morning America, The Oprah Winfrey Show, CNN, NPR, Dr. Radio, Nightline, Fox and Friends, The Steve Harvey Show, CBS This Morning, ABC News Now, NBCNightlyNews,20/20, and World News Tonight. She is an expert source for many magazines and serves on the medical advisory board of The Kinsey Institute, Self Magazine, and Prevention Magazine. She writes a regular column for The Ethel by AARP and Prevention Magazine. Subscribe and Follow Dr. Streicher on DrStreicher.com Instagram @DrStreich Facebook @DrStreicher YouTube DrStreicherTV Books by Lauren Streicher, MD Slip Sliding Away: Turning Back the Clock on Your Vagina-A gynecologist's guide to eliminating post-menopause dryness and pain Hot Flash Hell: A Gynecologist's Guide to Turning Down the Heat Sex Rx- Hormones, Health, and Your Best Sex Ever The Essential Guide to Hysterectomy
"Nanogod" was first published in Issue 003 of Dark Matter Magazine, May-Jun 2021. To purchase Issue 003 visit www.darkmattermagazine.shop. CREDITS Written by Larry Hodges Performed by Nick Robertson Sound Design by Alli Nova Produced by Phil McLaughlin We have three titles now available in our audiobook catalogue! Dark Matter Presents Haunted Reels: Stories from the Minds of Professional Filmmakers curated by David Lawson Jr., Rootwork by Tracy Cross, and Linghun by Ai Jiang are just the beginning of our growing Audible library of carefully edited and lightly sound designed audiobooks. Join us for the best and darkest of sci-fi and horror, and we'll see you in two weeks!
Mamileiros e mamiletes, o que inspira o Mamilos Cultura de hoje é o livro A Tirania do Mérito, de Michael J. Sandel. As democracias liberais estão em risco. E, de acordo com o filósofo Michael J. Sandel, o princípio do mérito, um de seus pilares básicos, é o responsável por esse cenário. A tirania do mérito propõe que para existir uma ética diferente e dignificadora, o sucesso deve ser compreendido em prol da coletividade. Indica que uma alternativa de pensamento guiado pela humildade, pela compreensão do papel do acaso na vida humana e pela criação real da oportunidade poderá ser, então, a melhor bússola para a democracia, para o bem comum. O livro foi publicado no Brasil pela editora Civilização Brasileira em 2020. Pra conversar sobre as reflexões inspiradas pelo livro, Ju Wallauer recebe o advogado e professor Thiago Amparo. Dá o play e vem com a gente! _____ NOVALGINA Se você estiver sentindo aquela dor forte intensa ou febre, não precisa ficar sofrendo esperando passar. Para esses momentos, vale ter Novalgina 1 grama em casa. Ela combate a dor intensa e a febre em minutos. Novalgina é um medicamento à base de dipirona de dupla ação, é analgésico e antitérmico. Além de ser uma marca de confiança, que há mais de 100 anos ajuda a cuidar das famílias brasileiras, é também a mais recomendada pelos médicos. É uma escolha certeira: vale o que custa, vale cada comprimido Acesse novalgina.com.br pra saber mais NOVALGINA® (dipirona monoidratada). Indicação: analgésico e antitérmico. M.S.: 1.8326.0351. O USO DO MEDICAMENTO PODE TRAZER ALGUNS RISCOS. Leia atentamente a bula. SE PERSISTIREM OS SINTOMAS, O MÉDICO DEVERÁ SER CONSULTADO. Junho/2023. MAT-BR-2303214. “combate a dor intensa e a febre em minutos”: 1- Bula Novalgina - profissional de saúde. *Início de ação de 30 a 60 minutos. 2- Ajgaonkar VS, Marathe SN, Virani AR. Dipyrone versus paracetamol: a double-blind study in typhoid fever. J Int Med Res. 1988 May-Jun;16(3):225-30. 3- Tulunay FC et al. The efficacy and safety of dipyrone (Novalgin) tablets in the treatment of acute migraine attacks: a double-blind, cross-over, randomized, placebo-controlled, multi-center study. Funct Neurol. 2004 Jul-Sep;19(3):197-202. “É também a mais recomendada pelos médicos: 4- IQVIA GPS FY'22 – Valores RX – Mercado de Analgésicos OTC _____ FALE CONOSCO . Email: mamilos@b9.com.br _____ CONTRIBUA COM O MAMILOS Quem apoia o Mamilos ajuda a manter o podcast no ar e ainda participa do nosso grupo especial no Telegram. É só R$9,90 por mês! Quem assina não abre mão. https://www.catarse.me/mamilos _____ Equipe Mamilos Mamilos é uma produção do B9 A apresentação é de Cris Bartis e Ju Wallauer. Pra ouvir todos episódios, assine nosso feed ou acesse mamilos.b9.com.br Quem coordenou essa produção foi Beatriz Souza. Com a estrutura de pauta e roteiro escrito por Cris Bartis e Ju Wallauer. A edição foi de Mariana Leão e as trilhas sonoras, de Angie Lopez. A coordenação digital é feita por Agê Barros. O B9 tem direção executiva de Cris Bartis, Ju Wallauer e Carlos Merigo. O atendimento e negócios é feito por Telma Zenaro.
Mamileiros e mamiletes, o que inspira o Mamilos Cultura de hoje é o documentário Alma Imoral, disponível no Canal Curta, no YouTube. O documentário “Alma Imoral”, dirigido pelo cineasta Silvio Tendler, reflete sobre os conceitos de corpo e alma, tradição e transcendência, obediência e ruptura, através do livro “A Alma Imoral”, publicado pelo rabino Nilton Bonder. O filme questiona o que acontece quando o “corpo moral” - normalmente apontado como instrumento importante para a preservação da espécie humana - se torna estreito e passa a ser um obstáculo ao futuro da humanidade. Como se dá esse processo imoral de transcendência, de transgressão, para que fronteiras sejam ampliadas? O documentário busca estabelecer pontes entre histórias de personagens da Bíblia que romperam com as tradições em busca de uma nova ordem - como Eva, Abraão, Moisés - e transgressores do nosso tempo em vários campos, como comportamento, ciência e política. Ali podemos ver israelenses que lutam pela paz ao lado de palestinos, rabinos gays, cientistas que defendem teorias controversas, entre outras histórias que expandem as fronteiras da nossa consciência e produzem a possibilidade de evolução. Dá o play e vem com a gente! _____ NOVALGINA Se você estiver sentindo aquela dor forte intensa ou febre, não precisa ficar sofrendo esperando passar. Para esses momentos, vale ter Novalgina 1 grama em casa. Ela combate a dor intensa e a febre em minutos. Novalgina é um medicamento à base de dipirona de dupla ação, é analgésico e antitérmico. Além de ser uma marca de confiança, que há mais de 100 anos ajuda a cuidar das famílias brasileiras, é também a mais recomendada pelos médicos. É uma escolha certeira: vale o que custa, vale cada comprimido Acesse novalgina.com.br pra saber mais NOVALGINA® (dipirona monoidratada). Indicação: analgésico e antitérmico. M.S.: 1.8326.0351. O USO DO MEDICAMENTO PODE TRAZER ALGUNS RISCOS. Leia atentamente a bula. SE PERSISTIREM OS SINTOMAS, O MÉDICO DEVERÁ SER CONSULTADO. Junho/2023. MAT-BR-2303214. “combate a dor intensa e a febre em minutos”: 1- Bula Novalgina - profissional de saúde. *Início de ação de 30 a 60 minutos. 2- Ajgaonkar VS, Marathe SN, Virani AR. Dipyrone versus paracetamol: a double-blind study in typhoid fever. J Int Med Res. 1988 May-Jun;16(3):225-30. 3- Tulunay FC et al. The efficacy and safety of dipyrone (Novalgin) tablets in the treatment of acute migraine attacks: a double-blind, cross-over, randomized, placebo-controlled, multi-center study. Funct Neurol. 2004 Jul-Sep;19(3):197-202. “É também a mais recomendada pelos médicos: 4- IQVIA GPS FY'22 – Valores RX – Mercado de Analgésicos OTC _____ FALE CONOSCO . Email: mamilos@b9.com.br _____ CONTRIBUA COM O MAMILOS Quem apoia o Mamilos ajuda a manter o podcast no ar e ainda participa do nosso grupo especial no Telegram. É só R$9,90 por mês! Quem assina não abre mão. https://www.catarse.me/mamilos _____ Equipe Mamilos Mamilos é uma produção do B9 A apresentação é de Cris Bartis e Ju Wallauer. Pra ouvir todos episódios, assine nosso feed ou acesse mamilos.b9.com.br Quem coordenou essa produção foi Beatriz Souza. Com a estrutura de pauta e roteiro escrito por Cris Bartis e Ju Wallauer. A edição foi de Mariana Leão e as trilhas sonoras, de Angie Lopez. A coordenação digital é feita por Agê Barros. O B9 tem direção executiva de Cris Bartis, Ju Wallauer e Carlos Merigo. O atendimento e negócios é feito por Telma Zenaro.
Mamileiros e mamiletes, o que inspira o Mamilos Cultura de hoje é a série “Xuxa, o documentário”, disponível no Globoplay. A série documental percorre a trajetória de Xuxa, com acervo exclusivo, entrevistas inéditas e reencontros significativos. Com todos os seus episódios já disponíveis, a série sobre Xuxa Meneghel conquistou um recorde de público para a Globo e se transformou no documentário mais visto no Globoplay. Dá o play e vem com a gente! _____ NOVALGINA Se você estiver sentindo aquela dor forte intensa ou febre, não precisa ficar sofrendo esperando passar. Para esses momentos, vale ter Novalgina 1 grama em casa. Ela combate a dor intensa e a febre em minutos. Novalgina é um medicamento à base de dipirona de dupla ação, é analgésico e antitérmico. Além de ser uma marca de confiança, que há mais de 100 anos ajuda a cuidar das famílias brasileiras, é também a mais recomendada pelos médicos. É uma escolha certeira: vale o que custa, vale cada comprimido. Acesse novalgina.com.br pra saber mais NOVALGINA® (dipirona monoidratada). Indicação: analgésico e antitérmico. M.S.: 1.8326.0351. O USO DO MEDICAMENTO PODE TRAZER ALGUNS RISCOS. Leia atentamente a bula. SE PERSISTIREM OS SINTOMAS, O MÉDICO DEVERÁ SER CONSULTADO. Junho/2023. MAT-BR-2303214. “combate a dor intensa e a febre em minutos”: 1- Bula Novalgina - profissional de saúde. *Início de ação de 30 a 60 minutos. 2- Ajgaonkar VS, Marathe SN, Virani AR. Dipyrone versus paracetamol: a double-blind study in typhoid fever. J Int Med Res. 1988 May-Jun;16(3):225-30. 3- Tulunay FC et al. The efficacy and safety of dipyrone (Novalgin) tablets in the treatment of acute migraine attacks: a double-blind, cross-over, randomized, placebo-controlled, multi-center study. Funct Neurol. 2004 Jul-Sep;19(3):197-202. “É também a mais recomendada pelos médicos: 4- IQVIA GPS FY'22 – Valores RX – Mercado de Analgésicos OTC _____ FALE CONOSCO . Email: mamilos@b9.com.br _____ CONTRIBUA COM O MAMILOS Quem apoia o Mamilos ajuda a manter o podcast no ar e ainda participa do nosso grupo especial no Telegram. É só R$9,90 por mês! Quem assina não abre mão. https://www.catarse.me/mamilos _____ Equipe Mamilos Mamilos é uma produção do B9 A apresentação é de Cris Bartis e Ju Wallauer. Pra ouvir todos episódios, assine nosso feed ou acesse mamilos.b9.com.br Quem coordenou essa produção foi Beatriz Souza. Com a estrutura de pauta e roteiro escrito por Cris Bartis e Ju Wallauer. A edição foi de Mariana Leão e as trilhas sonoras, de Angie Lopez. A coordenação digital é feita por Agê Barros. O B9 tem direção executiva de Cris Bartis, Ju Wallauer e Carlos Merigo. O atendimento e negócios é feito por Telma Zenaro.
Mamileiros e mamiletes, o que inspira o Mamilos Cultura é o filme Oppenheimer, dirigido por Christopher Nolan e baseado no livro biográfico vencedor do Prêmio Pulitzer, Prometeu Americano: O Triunfo e a Tragédia de J. Robert Oppenheimer, escrito por Kai Bird e Martin J. Sherwin. Ambientado na Segunda Guerra Mundial, o longa acompanha a vida de J. Robert Oppenheimer (Cillian Murphy), físico teórico da Universidade da Califórnia e diretor do Laboratório de Los Alamos durante o Projeto Manhattan - que tinha a missão de projetar e construir as primeiras bombas atômicas. Pra conversar sobre as reflexões que o filme inspira, Ju Wallauer recebe Bianca Dias, psicanalista, escritora, ensaísta e crítica de arte. Aperta o play e vamos juntos! _____ NOVALGINA Se você estiver sentindo aquela dor forte intensa ou febre, não precisa ficar sofrendo esperando passar. Para esses momentos, vale ter Novalgina 1 grama em casa. Ela combate a dor intensa e a febre em minutos. Novalgina é um medicamento à base de dipirona de dupla ação, é analgésico e antitérmico. Além de ser uma marca de confiança, que há mais de 100 anos ajuda a cuidar das famílias brasileiras, é também a mais recomendada pelos médicos. É uma escolha certeira: vale o que custa, vale cada comprimido Acesse novalgina.com.br pra saber mais NOVALGINA® (dipirona monoidratada). Indicação: analgésico e antitérmico. M.S.: 1.8326.0351. O USO DO MEDICAMENTO PODE TRAZER ALGUNS RISCOS. Leia atentamente a bula. SE PERSISTIREM OS SINTOMAS, O MÉDICO DEVERÁ SER CONSULTADO. Junho/2023. MAT-BR-2303214. “combate a dor intensa e a febre em minutos”: 1- Bula Novalgina - profissional de saúde. *Início de ação de 30 a 60 minutos. 2- Ajgaonkar VS, Marathe SN, Virani AR. Dipyrone versus paracetamol: a double-blind study in typhoid fever. J Int Med Res. 1988 May-Jun;16(3):225-30. 3- Tulunay FC et al. The efficacy and safety of dipyrone (Novalgin) tablets in the treatment of acute migraine attacks: a double-blind, cross-over, randomized, placebo-controlled, multi-center study. Funct Neurol. 2004 Jul-Sep;19(3):197-202. “É também a mais recomendada pelos médicos: 4- IQVIA GPS FY'22 – Valores RX – Mercado de Analgésicos OTC _____ FALE CONOSCO . Email: mamilos@b9.com.br _____ CONTRIBUA COM O MAMILOS Quem apoia o Mamilos ajuda a manter o podcast no ar e ainda participa do nosso grupo especial no Telegram. É só R$9,90 por mês! Quem assina não abre mão. https://www.catarse.me/mamilos _____ Equipe Mamilos Mamilos é uma produção do B9 A apresentação é de Cris Bartis e Ju Wallauer. Pra ouvir todos episódios, assine nosso feed ou acesse mamilos.b9.com.br Quem coordenou essa produção foi Beatriz Souza. Com a estrutura de pauta e roteiro escrito por Cris Bartis e Ju Wallauer. A edição foi de Mariana Leão e as trilhas sonoras, de Angie Lopez. A coordenação digital é feita por Agê Barros. O B9 tem direção executiva de Cris Bartis, Ju Wallauer e Carlos Merigo. O atendimento e negócios é feito por Telma Zenaro.
"Hounds of Thule" was first published in Issue 003 of Dark Matter Magazine, May-Jun 2021. To purchase Issue 003, visit www.darkmattermagazine.shop. CREDITS Written by Christine Lucas Performed by Erika Sanderson Sound Design by Alli Nesbit Produced by Phil McLaughlin
When you think of foundational clinical vestibular research, there is no doubt you think of one if not both of these individuals. Separately, they have contributed significantly to the profession and together, their collaborations have been transformative to the future of vestibular. Watch to hear us talk to Gary and Devin about where they started, how to promote successful research collaborations, and where they see the future of vestibular going. Here are some research articles Dr. Jacobson and Dr. McCaslin wanted to share with you: Development of the Tinnitus Handicap Inventory. Newman CW, Jacobson GP, Spitzer JB.Arch Otolaryngol Head Neck Surg. 1996 Feb;122(2):143-8. doi: 10.1001/archotol.1996.01890140029007.PMID: 8630207 Test-Retest Reliability of the Dizziness Symptom Profile. Landon-Lane RL, Piker EG, Jacobson GP, Hatton K, Roberts RA.Ear Hear. 2021 Jan/Feb;42(1):206-213. doi: 10.1097/AUD.0000000000000918.PMID: 32701727 Development and Preliminary Findings of the Dizziness Symptom Profile. Jacobson GP, Piker EG, Hatton K, Watford KE, Trone T, McCaslin DL, Bennett ML, Rivas A, Haynes DS, Roberts RA.Ear Hear. 2019 May/Jun;40(3):568-576. doi: 10.1097/AUD.0000000000000628.PMID: 29979254 Effects of age on the tuning of the cVEMP and oVEMP. Piker EG, Jacobson GP, Burkard RF, McCaslin DL, Hood LJ.Ear Hear. 2013 Nov-Dec;34(6):e65-73. doi: 10.1097/AUD.0b013e31828fc9f2.PMID: 23673615 Free PMC article. Intraoperative evoked potential monitoring. Jacobson GP, Tew JM Jr.J Clin Neurophysiol. 1987 Apr;4(2):145-76. doi: 10.1097/00004691-198704000-00004.PMID: 3305572 Review. A Comparison of Dizziness Handicap Inventory Scores by Categories of Vestibular Diagnoses Graham, M. K., Staab, J. P., Lohse, C. M., & McCaslin, D. L. (2021). A Comparison of Dizziness Handicap Inventory Scores by Categories of Vestibular Diagnoses. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 42(1), 129–136. https://doi.org/10.1097/MAO.000000000... The Component Structure of the Dizziness Handicap Inventory (DHI): A Reappraisal Van De Wyngaerde, K. M., Lee, M. K., Jacobson, G. P., Pasupathy, K., Romero-Brufau, S., & McCaslin, D. L. (2019). The Component Structure of the Dizziness Handicap Inventory (DHI): A Reappraisal. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 40(9), 1217–1223. https://doi.org/10.1097/MAO.000000000... The dissociation of video head impulse test (vHIT) and bithermal caloric test results provide topological localization of vestibular system impairment in patients with "definite" Ménière's disease McCaslin, D. L., Rivas, A., Jacobson, G. P., & Bennett, M. L. (2015). The dissociation of video head impulse test (vHIT) and bithermal caloric test results provide topological localization of vestibular system impairment in patients with "definite" Ménière's disease. American journal of audiology, 24(1), 1–10. https://doi.org/10.1044/2014_AJA-14-0040
INCOME REPORT - If you're not measuring what you're doing each month, it makes it difficult to make insightful decisions in the business, know what to change or know what to focus on the next month. Each month I go over my business revenue for Design and Coaching, expenses in the business, KPI's and some wins/loses in hopes to help you in your business.
"Drop Shipment Standard Procedure" was first published in Issue 003 of Dark Matter Magazine, May-Jun 2021. To purchase Issue 003, visit www.darkmattermagazine.shop. Keep your eyes on Fantasia International Film Festival, we'll be debuting our anthology Haunted Reels! CREDITS Written by Marie Croke Performed by Shaina Summerville Sound Design by Alli Nesbit Produced by Phil McLaughlin
There is nothing more stressful than seeing EMS peri-arrest progress to pulseless. CARES data suggest that cardiac arrest during transport is not an uncommon event. Additionally, there is new evidence that these patients may not be as difficult to recognize as we might've thought. Join the podcast crew as we introduce the MCHD "MOVES" algorithm for a proactive approach to providing a safety net before transporting our critical patients. REFERENCES 1. Clemency BM, Murk W, Moore A, Brown LH. The EMS Modified Early Warning Score (EMEWS): A Simple Count of Vital Signs as a Predictor of Out-of-Hospital Cardiac Arrests. Prehosp Emerg Care. 2022 May-Jun;26(3):391-399. 2. Burnett SJ, Innes JC, Varughese R, Frazer E, Clemency BM. A Qualitative Analysis of the Experiences of EMS Clinicians in Recognizing and Treating Witnessed Cardiac Arrests. Prehosp Emerg Care. 2022 Sep 28:1-9.
After returning to the US in late April 2022, The War On Drugs took a short break berore heading back out on an intense 7-week tour that took the band to Mexico, across the US, and back to Europe. After a massive show with The Strokes in Mexico City, the band returned to the US for a tour that concluded at Bonnaroo in June. They made a quick turnaround, and headed back to Europe for a show opening for The Rolling Stones in London, as well as run of mostly festival dates across Europe. Despite a Covid outbreak that took down 3 members of the tour party simultaneously, the band and crew rallied to support each other once more, and by the time they returned to the States in early July, they'd successfully crushed another 28 shows.Host: Dominic EastGuests: Adam Granduciel, Dave Hartley, Robbie Bennett, Charlie Hall, Anthony LaMarca, Jon Natchez, Eliza Hardy-Jones, Craig McQuiston
"Check, Please." was first published in Issue 003 of Dark Matter Magazine, May-Jun 2021. To purchase Issue 003, visit www.darkmattermagazine.shop. Keep your eyes on Fantasia International Film Festival, we'll be debuting our anthology Haunted Reels! CREDITS Written by Sophie Jaff Performed by Alli Nesbit Sound Design by Alli Nesbit Produced by Phil McLaughlin
"The House of Shapes" was first published in Issue 003 of Dark Matter Magazine, May-Jun 2021. To purchase Issue 003, visit www.darkmattermagazine.shop. "Linghun" by Ai Jiang is a tale of haunting specters and the grief sick town that perpetuates them. "Linghun" is our first Dark Matter INK audiobook: now available now in our shop! CREDITS Written by Hailey Piper Performed by Piper Reese Sound Design and Editing by Alli Nesbit Produced by Phil McLaughlin
You Are More Than Just Your Breast Cancer - Hormones and Breast Cancer Dr. Corinne Menn is a board certified OBGYN and North American Menopause Society Certified Menopause Practitioner. She has a special interest in areas often neglected in women's health: Perimenopause and menopause, the unique needs of female cancer survivors and those at high risk for breast cancer. Dr. Menn tells us her story of breast cancer dx at age 28, going through menopause three times and is now a pro-hormone educator. Dr. Menn discusses taking systemic hormones and her journey and how it has changed her life. Why are doctors and patients so afraid of hormones? Doctors are so risk adverse – but let's talk about the risks of not treating menopause. The myth that estrogen causes cancer. How Tamoxifen works. Breast cancer nomenclature – estrogen positive – this doesn't mean estrogen caused the cancer – we clarify. The nuance of being overweight and risk of breast cancer. The number one killer of women with history of breast cancer is heart disease. Safety of systemic hormone replacement therapy in breast cancer survivors Article in Breast Cancer Research and Treatment · January 2022 – Dr Bluming - "Twenty-five studies of HRT after a breast cancer diagnosis, published between 1980 and 2013, are discussed, as are the 20 reviews of those studies published between 1994 and 2021. Only 1 of the 25 studies, the HABITS trial, demonstrated an increased risk of recurrence, which was limited to local or contralateral, and not distant, recurrence. None of the studies, including HABITS, reported increased breast cancer mortality associated with HRT. Even in the HABITS trial, the absolute increase in the number of women who had a recurrence (localized only) associated with HRT administration was 22. It is on the basis of these 22 patients that HRT, with its demonstrated benefits for so many aspects of women's health, is being denied to millions of breast cancer survivors around the world." The problem with the HABITS trial. Why are we scaring women so much about breast cancer? Who is the right breast cancer survivor to start hormones? A good candidate? Are we overtreating with aromatase inhibitors? Podcast partnership today: Always Discreet https://www.instagram.com/alwaysdiscreet/ Bluming AZ. Hormone Replacement Therapy After Breast Cancer: It Is Time. Cancer J. 2022 May-Jun 01;28(3):183-190. Young Survival Coalition https://youngsurvival.org/ Vaginal Estrogen for people with a history of breast cancer: https://www.acog.org/clinical/clinical-guidance/clinical-consensus/articles/2021/12/treatment-of-urogenital-symptoms-in-individuals-with-a-history-of-estrogen-dependent-breast-cancer Dr. Menn is an Alloy Health Medical Advisor and Prescriber www.myalloy.com http://www.drmenn.com/ https://www.instagram.com/drmennobgyn https://www.tiktok.com/@drmennobgyn https://www.facebook.com/drmenn
Morton's Neuroma Diagnosis Treatment and Regenerative Medicine Options Claim CME for listening The CE experience for this Podcast is powered by CMEfy - click here to reflect and earn credits: https://earnc.me/7Oo1wq Dr Rosenblum discusses Morton's Neuroma and describes typical presentation, diagnosis, treatments such as corticosteroid injection, nerve ablation, regenerative medicine and more! Morton's neuroma is a painful condition that affects the foot, specifically the ball of the foot. It occurs when the tissue surrounding the nerves leading to the toes thickens, causing intense pain, numbness, or a burning sensation. Course Calendar Practice Management Webinar: The End of the Public Health Emergency. What's Changed and what Opportunities Remain! Regenerative Pain Medicine Course NYC- May 13 Pain Management Board Review/Refresher Course/ Ultrasound Training NYC- June 9-11, 2023 Ultrasound Guided Regional Anesthesia and Pain Medicine NYC- July 19, 2023 Ultrasound Guided Regional Anesthesia and Pain Medicine NYC- August 19th, 2023 Ultrasound Guided Regional Anesthesia and Pain Medicine- Sept 15, 2023, San Juan, PR For up to date Calendar, Click Here! References Platelet-rich-plasma Injection Therapy For Morton's Neuroma - Page #4. https://www.amssm.org/plateletrichplasma_injecti-csa-268.html?StartPos=130&Part=4a Bhatia M, Thomson L. Morton's neuroma - Current concepts review. J Clin Orthop Trauma. 2020 May-Jun;11(3):406-409. doi: 10.1016/j.jcot.2020.03.024. Epub 2020 Apr 10. PMID: 32405199; PMCID: PMC7211826. Barbara De Angelis, Lucilla Lucarini, Fabrizio Orlandi, Annarita Agovino, Alessia Migner, Valerio Cervelli, Valentina Izzo, Cristiano Curcio. Regenerative surgery of the complications with Morton's neuroma surgery: use of platelet rich plasma and hyaluronic acidVolume10, Issue4 August 2013 Pages 372-376
"Death in the Afternoon" was first published in Issue 003 of Dark Matter Magazine, May-Jun 2021. To purchase Issue 003, visit www.darkmattermagazine.shop. "Linghun" by Ai Jiang is a tale of haunting specters and the grief sick town that perpetuates them. "Linghun" is our first Dark Matter INK audiobook: now available now in our shop! CREDITS Written by John G. Wimer Performed by Aaron Sinn Sound Design by Alli Nesbit Produced by Phil McLaughlin
Please join Drs. Graham Skelhorne-Gross, Jordan Nantais and Ashlie Nadler from our Emergency General Surgery Team for a discussion on cirrhotic patients. Child-Pugh Score (https://www.mdcalc.com/calc/340/child-pugh-score-cirrhosis-mortality) · Bilirubin, albumin, INR, ascites, encephalopathy · Used to predict operative mortality based on cirrhosis severity · Mortality in EGS: - Child-Pugh A: 10% electively and 22% emergently - Child-Pugh B: 30% electively and 38% emergently - Child-Pugh C: 80% electively and up to 100% emergently Model for End Stage Liver Disease (MELD) (https://www.mdcalc.com/calc/10437/model-end-stage-liver-disease-meld?utm_source=site&utm_medium=link&utm_campaign=meld_12_and_older) · creatinine, bilirubin, INR, and sodium · MELD < 20 – 1% increase in mortality with each point increase · MELD > 20 – 2% increase in mortality with each point increase Pre-operative Planning · Identification of cirrhosis with physical examination, bloodwork and imaging · Involvement of other medical services (internal medicine, hepatology, ICU) as needed · Cirrhosis optimization, if possible · Abdominal wall mapping Unexpected Intraoperative Finding Communicate unexpected findings to the operative team and think of additional adjuncts you may need such as additional ports, topical hemostatic agents or energy devices. Think about why you are in the OR. If its an elective situation and can wait, consider bailing. If its emergent, you may have to do something more definitive. Exposure may be a challenge, you may have to alter your typical approach including where the assistant grabs and retracts. Extra hands are helpful. Bleeding can be a big deal. If possible, map out the abdominal wall ahead of time with cross-sectional imaging. Stay away from varices around the umbilicus or porta Ventral Hernia + Cirrhosis · Ideally, control ascites pre-operatively, if you can't consider leaving drains · Small (< 2cm) hernias close primarily · Larger (>2cm) hernias repair with mesh unless infected filed (controversial) · Minimally invasive repairs can be performed Benign Biliary Disease + Cirrhosis · Incidence of gallstones is 4-5 times higher in cirrhotic patients · Prophylactic laparoscopic cholecystectomy (LC) generally not done · LC generally considered acceptable in CP A or B but not C (exceptions: HD instability, gangrenous cholecystitis, hemorrhagic cholecystitis) · Cholecystostomy and ERCP are safe References: Bleszynski, M. et. Al. Acute care and emergency general surgery in patients with chronic liver disease: how can be optimize perioperative care? A review of the literature. 2018. World Journal of Emergency Surgery; 13:32 Mansour A, Watson W, Shayani V, et al. Abdominal operations in patients with cirrhosis: still a major surgical challenge. Surgery. 1997;122:730–5. Yeom SK, Lee CH, Cha SH, Park CM. Prediction of liver cirrhosis, using diagnostic imaging tools. World J Hepatol. 2015 Aug 18;7(17):2069-79. doi: 10.4254/wjh.v7.i17.2069. PMID: 26301049; PMCID: PMC4539400. Jain D, Mahmood E, V-Bandres M, Feyssa E. Preoperative elective transjugular intrahepatic portosystemic shunt for cirrhotic patients undergoing abdominal surgery. Ann Gastroenterol. 2018 May-Jun;31(3):330-337. doi: 10.20524/aog.2018.0249. Epub 2018 Mar 15. PMID: 29720858; PMCID: PMC5924855. **Fellowship application link: https://forms.gle/PiKM2MMQpE5jSAeW7 Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more. If you liked this episode, check out other Emergency General Surgery episode here: https://behindtheknife.org/podcast-category/emergency-general-surgery/
Essentially all women eventually enter menopause, and while most end up not taking hormones to treat their symptoms, they at least have the option to do so. Women with a breast cancer diagnosis, on the other hand, generally don't have the same choices at their disposal and are told, or assume, they are not candidates for estrogen therapy. Millions of women are expected to just put up with hot flashes, brain fog, insomnia, and bone loss, not to mention all the changes below the belly button. In this episode, I am joined by Dr. Corinne Menn, a board-certified gynecologist, with expertise in menopause and sexual medicine who was diagnosed with estrogen-positive breast cancer in her 20s. We will have a radical discussion about options, INCLUDING ESTROGEN to manage hot flashes and insomnia. In this episode, we discuss: The impact of PREGNANCY on women with breast cancer Non-estrogen prescription options to treat HOT FLASHES SSRI, SNRI Gabapentin Oxybutynin Fezolinetant ESTROGEN THERAPY as an option for women with breast cancer The lack of studies that show estrogen increases the risk of breast cancer recurrence or mortality The 25 scientific studies that support the safety of taking menopausal estrogen therapy in women with breast cancer Why physicians continue to tell women to avoid estrogen If it is worth taking herbal or other over-the-counter hot flash remedies Article Dr. Menn references: Bluming AZ. Introduction: Estrogen Reconsidered: Exploring the Evidence for Estrogen's Benefits and Risks. Cancer J. 2022 May-Jun 01;28(3):157-162. MORE INFORMATION Episode 2:Think Your Hot Flashes Can't Kill You? Think Again! Episode 3: What's Up Down There? Genital Dryness & Misbehaving Bladders Episode 11: Vaginal Estrogen is Not Poison Episode 31 The TRUTH About Hormone Therapy: Does it CAUSE or Does it PREVENT Breast Cancer? Slip Sliding Away: Turning Back the Clock on Your Vagina-A gynecologist's guide to eliminating post-menopause dryness and pain Hot Flash Hell: A Gynecologist's Guide to Turning Down the Heat Lauren Streicher, MD is a clinical professor of obstetrics and gynecology at Northwestern University's Feinberg School of Medicine, and the founding medical director of the Northwestern Medicine Center for Sexual Medicine and Menopause. She is a certified menopause practitioner of the North American Menopause Society. Sign up to receive DR. STREICHER'S FREE NEWSLETTER Dr. Streicher is the medical correspondent for Chicago's top-rated news program, the WGN Morning News, and has been seen on The Today Show, Good Morning America, The Oprah Winfrey Show, CNN, NPR, Dr. Radio, Nightline, Fox and Friends, The Steve Harvey Show, CBS This Morning, ABC News Now, NBCNightlyNews,20/20, and World News Tonight. She is an expert source for many magazines and serves on the medical advisory board of The Kinsey Institute, Self Magazine, and Prevention Magazine. She writes a regular column for The Ethel by AARP and Prevention Magazine. Subscribe and Follow Dr. Streicher on DrStreicher.com Instagram @DrStreich Twitter @DrStreicher Facebook @DrStreicher YouTube DrStreicherTV Books by Lauren Streicher, MD Slip Sliding Away: Turning Back the Clock on Your Vagina-A gynecologist's guide to eliminating post-menopause dryness and pain Hot Flash Hell: A Gynecologist's Guide to Turning Down the Heat Sex Rx- Hormones, Health, and Your Best Sex Ever The Essential Guide to Hysterectomy
In this special annual episode we look back at 2022 and ask the I Ching what our learning should have been in the powerful year just past. And then we look to 2023 and explore through the I Ching where our focus should be to really maximise the goodness of the year ahead. Listen to this episode for more insight into how to work with this flow this week. I Ching Resources, Links and Giveaways: https://linktr.ee/ichingcafe Timestamps 0:00 Intro 5:50 2022 Learning - Hexagram 53 Development 7:04 2022 Learning - Hexagram 53 Development, Changing Line 1 7:42 2022 Learning - Hexagram 37 The Family 9:46 2023 Focus - Hexagram 63 After Completion 12:46 2023 Focus - Hexagram 38 Opposition 16:09 2023 Focus - Hexagram 63 After Completion, Changing Line 2, Jan-Feb 2023 17:53 2023 Focus - Hexagram 63 After Completion, Changing Line 3, Mar-Apr 2023 19:22 2023 Focus - Hexagram 63 After Completion, Changing Line 4, May-Jun 2023 20:22 2023 Focus - Hexagram 63 After Completion, Changing Line 5, Jul-Aug 2023 21:21 2023 Focus - Hexagram 63 After Completion, Changing Line 6, Sep-Oct 2023 Tech Specs 2022 Learning Main or Present Hexagram - Hexagram 53 Development Changing Lines - 1st Position Outcome Hexagram - Hexagram 37 The Family 2023 Focus Main or Present Hexagram - Hexagram 63 After Completion Changing Lines - 2nd, 3rd, 4th, 5th and 6th Positions Outcome Hexagram - Hexagram 38 Opposition
Dr. Kimberly Blumenthal (@KimberlyBlumen1), Dr. Meghan Jeffres (@PharmerMeg), and Dr. Eric Macy (@EricMacyMD) join Dr. Julie Ann Justo (@julie_justo) to summarize the history of cephalosporin avoidance in penicillin allergies, evidence-based pros and cons of giving cephalosporins in penicillin allergy, how to leverage technology to improve treatment of patients with penicillin allergies, and much more! Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm (https://twitter.com/SIDPharm) Instagram: @SIDPharm (https://www.instagram.com/sidpharm/) Facebook: https://www.facebook.com/sidprx LinkedIn: https://www.linkedin.com/company/sidp/ References Macy E. Why Was There Ever a Warning Not to Use Cephalosporins in the Setting of a Penicillin "Allergy"? J Allergy Clin Immunol Pract. 2021 Nov;9(11):3929-3933. doi: 10.1016/j.jaip.2021.06.059. PMID: 34303019. Liang EH, et al. Adverse Reactions Associated with Penicillins, Carbapenems, Monobactams, and Clindamycin: A Retrospective Population-based Study. J Allergy Clin Immunol Pract. 2020 Apr;8(4):1302-1313.e2. doi: 10.1016/j.jaip.2019.11.035. PMID: 31821919. Macy E, Contreras R. Adverse reactions associated with oral and parenteral use of cephalosporins: A retrospective population-based analysis. J Allergy Clin Immunol. 2015 Mar;135(3):745-52.e5. doi: 10.1016/j.jaci.2014.07.062. PMID: 25262461. Macy E, et al. Population-Based Incidence of New Ampicillin, Cephalexin, Cefaclor, and Sulfonamide Antibiotic "Allergies" in Exposed Individuals with and without Preexisting Ampicillin, Cephalexin, or Cefaclor "Allergies". J Allergy Clin Immunol Pract. 2022 Feb;10(2):550-555. doi: 10.1016/j.jaip.2021.10.043. PMID: 34757066. Picard M, et al. Cross-Reactivity to Cephalosporins and Carbapenems in Penicillin-Allergic Patients: Two Systematic Reviews and Meta-Analyses. J Allergy Clin Immunol Pract. 2019 Nov-Dec;7(8):2722-2738.e5. doi: 10.1016/j.jaip.2019.05.038. PMID: 31170539. Romano A, et al. Cross-reactivity and tolerability of aztreonam and cephalosporins in subjects with a T cell-mediated hypersensitivity to penicillins. J Allergy Clin Immunol. 2016 Jul;138(1):179-186. doi: 10.1016/j.jaci.2016.01.025. PMID: 27016799. Romano A, et al. Cross-Reactivity and Tolerability of Cephalosporins in Patients with IgE-Mediated Hypersensitivity to Penicillins. J Allergy Clin Immunol Pract. 2018 Sep-Oct;6(5):1662-1672. doi: 10.1016/j.jaip.2018.01.020. PMID: 29408440. Blumenthal KG, et al. The Impact of a Reported Penicillin Allergy on Surgical Site Infection Risk. Clin Infect Dis. 2018 Jan 18;66(3):329-336. doi: 10.1093/cid/cix794. PMID: 29361015. Blumenthal KG, et al. Risk of meticillin resistant Staphylococcus aureus and Clostridium difficile in patients with a documented penicillin allergy: population based matched cohort study. BMJ. 2018 Jun 27;361:k2400. doi: 10.1136/bmj.k2400. PMID: 29950489. Blumenthal KG, et al. Recorded Penicillin Allergy and Risk of Mortality: a Population-Based Matched Cohort Study. J Gen Intern Med. 2019 Sep;34(9):1685-1687. doi: 10.1007/s11606-019-04991-y. PMID: 31011962. Macy E, Contreras R. Health care use and serious infection prevalence associated with penicillin "allergy" in hospitalized patients: A cohort study. J Allergy Clin Immunol. 2014 Mar;133(3):790-6. doi: 10.1016/j.jaci.2013.09.021. PMID: 24188976. AAAI. Choosing Wisely. 2014 Mar 3. https://www.choosingwisely.org/clinician-lists/american-academy-allergy-asthma-immunlogy-non-beta-lactam-antibiotics-penicillin-allergy/ Jeffres MN, et al. Systematic review of professional liability when prescribing β-lactams for patients with a known penicillin allergy. Ann Allergy Asthma Immunol. 2018 Nov;121(5):530-536. doi: 10.1016/j.anai.2018.03.010. PMID: 29551402. Macy E, et al. Association Between Removal of a Warning Against Cephalosporin Use in Patients With Penicillin Allergy and Antibiotic Prescribing. JAMA Netw Open. 2021 Apr 1;4(4):e218367. doi: 10.1001/jamanetworkopen.2021.8367. PMID: 33914051. Blumenthal KG, et al. Addressing Inpatient Beta-Lactam Allergies: A Multihospital Implementation. J Allergy Clin Immunol Pract. 2017 May-Jun;5(3):616-625.e7. doi: 10.1016/j.jaip.2017.02.019. PMID: 28483315. Jeffres M. Penicillin and/or Beta-Lactam Allergy Tip Sheet & Cross-reactivity Table. https://drive.google.com/file/d/1cokYXnSDlO3vk8ke1LaalPz4iavuNSV8/view?usp=share_link Khan DA, et al. Drug allergy: A 2022 practice parameter update. J Allergy Clin Immunol. 2022 Sep 17:S0091-6749(22)01186-1. doi: 10.1016/j.jaci.2022.08.028. Epub ahead of print. PMID: 36122788. Guyer AC, et al. Allergy Electronic Health Record Documentation: A 2022 Work Group Report of the AAAAI Adverse Reactions to Drugs, Biologicals, and Latex Committee. J Allergy Clin Immunol Pract. 2022 Nov;10(11):2854-2867. doi: 10.1016/j.jaip.2022.08.020. PMID: 36151034. Iammatteo M, et al. Safety and Outcomes of Oral Graded Challenges to Amoxicillin without Prior Skin Testing. J Allergy Clin Immunol Pract. 2019 Jan;7(1):236-243. doi: 10.1016/j.jaip.2018.05.008. PMID: 29802906. Bavbek S, et al. Determinants of nocebo effect during oral drug provocation tests. Allergol Immunopathol (Madr). 2015 Jul-Aug;43(4):339-45. doi: 10.1016/j.aller.2014.04.008. PMID: 25088674. DePestel DD, et al. Cephalosporin use in treatment of patients with penicillin allergies. J Am Pharm Assoc (2003). 2008 Jul-Aug;48(4):530-40. doi: 10.1331/JAPhA.2008.07006. PMID: 18653431. Check out our podcast host, Pinecast. Start your own podcast for free with no credit card required. If you decide to upgrade, use coupon code r-7e7a98 for 40% off for 4 months, and support Breakpoints. Check out our podcast host, Pinecast. Start your own podcast for free with no credit card required. If you decide to upgrade, use coupon code r-7e7a98 for 40% off for 4 months, and support Breakpoints.
This episode we discuss some of the big events happening in the world during May/Jun 2022, well... the ones that piqued our interests such as the Depp vs Heard trial, reboots coming our way, the Marvel Cineverse and much more! I think... #2ndbottlenojudgement
Drs. Tom Dilworth and Stephanie Shealy May (@stephshealymay) join Dr. Rachel Britt (@RachelBPharmD) in the first episode of Breakpoints Dosing Consults to discuss questions and debates around ceftriaxone dosing. When should we use 1g over 2g? How does critical illness affect what dose to use? Is ceftriaxone the most approachable antibiotic? Tune in for answers to these questions and more! Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm (https://twitter.com/SIDPharm) Instagram: @SIDPharm (https://www.instagram.com/sidpharm/) Facebook: https://www.facebook.com/sidprx LinkedIn: https://www.linkedin.com/company/sidp/ References Ettestad PJ, Campbell GL, Welbel SF, Genese CA, Spitalny KC, Marchetti CM, Dennis DT. Biliary complications in the treatment of unsubstantiated Lyme disease. J Infect Dis. 1995 Feb;171(2):356-61. doi: 10.1093/infdis/171.2.356. PMID: 7844372. Hasegawa S, Sada R, Yaegashi M, Morimoto K, Mori T; Adult Pneumonia Study Group-Japan. 1g versus 2 g daily intravenous ceftriaxone in the treatment of community onset pneumonia - a propensity score analysis of data from a Japanese multicenter registry. BMC Infect Dis. 2019 Dec 26;19(1):1079. doi: 10.1186/s12879-019-4552-8. PMID: 31878894; PMCID: PMC6933656. Barber KE, Loper JT, Morrison AR, Stover KR, Wagner JL. Impact of Obesity on Ceftriaxone Efficacy. Diseases. 2020 Jul 9;8(3):27. doi: 10.3390/diseases8030027. PMID: 32660113; PMCID: PMC7563366. Herrera-Hidalgo L, de Alarcón A, López-Cortes LE, Luque-Márquez R, López-Cortes LF, Gutiérrez-Valencia A, Gil-Navarro MV. Is Once-Daily High-Dose Ceftriaxone plus Ampicillin an Alternative for Enterococcus faecalis Infective Endocarditis in Outpatient Parenteral Antibiotic Therapy Programs? Antimicrob Agents Chemother. 2020 Dec 16;65(1):e02099-20. doi: 10.1128/AAC.02099-20. Erratum in: Antimicrob Agents Chemother. 2021 May 18;65(6): PMID: 33046488; PMCID: PMC7927845. Herrera-Hidalgo L, Lomas-Cabezas JM, López-Cortés LE, Luque-Márquez R, López-Cortés LF, Martínez-Marcos FJ, de la Torre-Lima J, Plata-Ciézar A, Hidalgo-Tenorio C, García-López MV, Vinuesa D, Gutiérrez-Valencia A, Gil-Navarro MV, De Alarcón A. Ampicillin Plus Ceftriaxone Combined Therapy for Enterococcus faecalis Infective Endocarditis in OPAT. J Clin Med. 2021 Dec 21;11(1):7. doi: 10.3390/jcm11010007. PMID: 35011748; PMCID: PMC8745305. Workowski KA, Bachmann LH, Chan PA, Johnston CM, Muzny CA, Park I, Reno H, Zenilman JM, Bolan GA. Sexually Transmitted Infections Treatment Guidelines, 2021. MMWR Recomm Rep. 2021 Jul 23;70(4):1-187. doi: 10.15585/mmwr.rr7004a1. PMID: 34292926; PMCID: PMC8344968. Whittles LK, White PJ, Paul J, Didelot X. Epidemiological Trends of Antibiotic Resistant Gonorrhoea in the United Kingdom. Antibiotics (Basel). 2018 Jul 13;7(3):60. doi: 10.3390/antibiotics7030060. PMID: 30011825; PMCID: PMC6165062. Ackerman A, Zook NR, Siegrist JF, Brummitt CF, Cook MM, Dilworth TJ. Comparison of Clinical Outcomes among Intensive Care Unit Patients Receiving One or Two Grams of Ceftriaxone Daily. Antimicrob Agents Chemother. 2020 May 21;64(6):e00066-20. doi: 10.1128/AAC.00066-20. PMID: 32205348; PMCID: PMC7269488. Ulldemolins M, Roberts JA, Rello J, Paterson DL, Lipman J. The effects of hypoalbuminaemia on optimizing antibacterial dosing in critically ill patients. Clin Pharmacokinet. 2011 Feb;50(2):99-110. doi: 10.2165/11539220-000000000-00000. PMID: 21142293. Dailly E, Arnould JF, Fraissinet F, Naux E, Letard de la Bouralière MA, Bouquié R, Deslandes G, Jolliet P, Le Floch R. Pharmacokinetics of ertapenem in burns patients. Int J Antimicrob Agents. 2013 Jul;42(1):48-52. doi: 10.1016/j.ijantimicag.2013.02.021. Epub 2013 Apr 8. PMID: 23578794. Pai MP. Treatment of bacterial infections in obese adult patients: how to appropriately manage antimicrobial dosage. Curr Opin Pharmacol. 2015 Oct;24:12-7. doi: 10.1016/j.coph.2015.06.004. Epub 2015 Jun 25. PMID: 26119488. Mahmood I. Theoretical versus empirical allometry: Facts behind theories and application to pharmacokinetics. J Pharm Sci. 2010 Jul;99(7):2927-33. doi: 10.1002/jps.22073. PMID: 20127826. Kang N, Housman ST, Nicolau DP. Assessing the Surrogate Susceptibility of Oxacillin and Cefoxitin for Commonly Utilized Parenteral Agents against Methicillin-Susceptible Staphylococcus aureus: Focus on Ceftriaxone Discordance between Predictive Susceptibility and in Vivo Exposures. Pathogens. 2015 Jul 30;4(3):599-605. doi: 10.3390/pathogens4030599. PMID: 26264030; PMCID: PMC4584275. Gern BH, Greninger AL, Weissman SJ, Stapp JR, Tao Y, Qin X. Continued in vitro cefazolin susceptibility in methicillin-susceptible Staphylococcus aureus. Ann Clin Microbiol Antimicrob. 2018 Feb 20;17(1):5. doi: 10.1186/s12941-018-0257-x. PMID: 29463249; PMCID: PMC5819674. Bremmer DN, Balada-Llasat JM, Goff DA, Bauer KA. Ceftriaxone Etest non-susceptible methicillin susceptible Staphylococcus aureus time-kill responses. Diagn Microbiol Infect Dis. 2017 Jun;88(2):192-194. doi: 10.1016/j.diagmicrobio.2017.02.019. Epub 2017 Mar 2. PMID: 28291629. Kosowska-Shick K, McGhee PL, Appelbaum PC. Affinity of ceftaroline and other beta-lactams for penicillin-binding proteins from Staphylococcus aureus and Streptococcus pneumoniae. Antimicrob Agents Chemother. 2010 May;54(5):1670-7. doi: 10.1128/AAC.00019-10. Epub 2010 Mar 1. PMID: 20194704; PMCID: PMC2863635. Palmer SM, Kang SL, Cappelletty DM, Rybak MJ. Bactericidal killing activities of cefepime, ceftazidime, cefotaxime, and ceftriaxone against Staphylococcus aureus and beta-lactamase-producing strains of Enterobacter aerogenes and Klebsiella pneumoniae in an in vitro infection model. Antimicrob Agents Chemother. 1995 Aug;39(8):1764-71. doi: 10.1128/AAC.39.8.1764. PMID: 7486916; PMCID: PMC162823. Craig WA. Interrelationship between pharmacokinetics and pharmacodynamics in determining dosage regimens for broad-spectrum cephalosporins. Diagn Microbiol Infect Dis. 1995 May-Jun;22(1-2):89-96. doi: 10.1016/0732-8893(95)00053-d. PMID: 7587056. Garot D, Respaud R, Lanotte P, Simon N, Mercier E, Ehrmann S, Perrotin D, Dequin PF, Le Guellec C. Population pharmacokinetics of ceftriaxone in critically ill septic patients: a reappraisal. Br J Clin Pharmacol. 2011 Nov;72(5):758-67. doi: 10.1111/j.1365-2125.2011.04005.x. PMID: 21545483; PMCID: PMC3243010. Joynt GM, Lipman J, Gomersall CD, Young RJ, Wong EL, Gin T. The pharmacokinetics of once-daily dosing of ceftriaxone in critically ill patients. J Antimicrob Chemother. 2001 Apr;47(4):421-9. doi: 10.1093/jac/47.4.421. PMID: 11266414. Van Wart SA et al., ICAAC 2009, poster # A1-010 Housman ST, Sutherland CA, Nicolau DP. Pharmacodynamic profile of commonly utilised parenteral therapies against meticillin-susceptible and meticillin-resistant Staphylococcus aureus collected from US hospitals. Int J Antimicrob Agents. 2014 Sep;44(3):235-41. doi: 10.1016/j.ijantimicag.2014.05.012. Epub 2014 Jun 24. PMID: 25052866. Zelenitsky SA, Beahm NP, Iacovides H, Ariano RE, Zhanel G. Limitations of ceftriaxone compared with cefazolin against MSSA: an integrated pharmacodynamic analysis. J Antimicrob Chemother. 2018 Jul 1;73(7):1888-1894. doi: 10.1093/jac/dky120. PMID: 29635472. Paul M, Zemer-Wassercug N, Talker O, Lishtzinsky Y, Lev B, Samra Z, Leibovici L, Bishara J. Are all beta-lactams similarly effective in the treatment of methicillin-sensitive Staphylococcus aureus bacteraemia? Clin Microbiol Infect. 2011 Oct;17(10):1581-6. doi: 10.1111/j.1469-0691.2010.03425.x. Epub 2010 Dec 14. PMID: 21073629. Carr DR, Stiefel U, Bonomo RA, Burant CJ, Sims SV. A Comparison of Cefazolin Versus Ceftriaxone for the Treatment of Methicillin-Susceptible Staphylococcus aureus Bacteremia in a Tertiary Care VA Medical Center. Open Forum Infect Dis. 2018 May 18;5(5):ofy089. doi: 10.1093/ofid/ofy089. PMID: 30568987; PMCID: PMC5961173. Check out our podcast host, Pinecast. Start your own podcast for free with no credit card required. If you decide to upgrade, use coupon code r-7e7a98 for 40% off for 4 months, and support Breakpoints.
Beth underwent gender transition from natal female to trans male and has since de-transitioned. In her early teens, Beth felt she was not like other women and began to question her gender. She saw people who were nonconforming, but although she adopted a non-binary identity in college, people still saw her as a woman. Beth became drawn to a masculine identity and associated transitioning gender with empowerment: she would be free from the perceived social constraints and physical vulnerabilities of womanhood. Beth's parents, the therapist she saw a few times, and the surgeon all affirmed her desire to transition. Beth underwent testosterone therapy and top surgery to remove her breasts, sacrifices in service of liberation. In time, however, Beth discovered that physical changes did not transform her inner world, and her post-surgical chest remains numb. Beth says, “de-transitioning brought me down to earth” and into adulthood. She feels some of her urges to transition were healthy, and some were self-annihilating—and wishes she had had more help in differentiating her inner world from her gender expression. Beth hopes to be a voice for the complexity of gender transitioning. Here's Beth's dream: “I met a woman in a lush forest. The forest was filled with strange relics—an abandoned child's playground, a little home, and abandoned campsites. I knew she was a detransitioner, but unlike me, she was proud, unabashed, and free. She told me I could be free like her once no one knew where to find me. Then she ran off into the jungle. There was an exhilarating feeling of freedom and hope.” BEYOND THE BREAKING POINT Music and lyrics by Wells Hanley ©2021You were my lost loverI tried for so longjust to find you here beside meI was so wrongI wandered darkened highwaysI turned every stonefar beyond the point of breakingbut I was never aloneSo afraid I would die waitingHow I hoped you would be thereand that you'd find meout beyond the breaking point So I swam in shark filled watersI swam in despairMy flesh was eaten, bruised, and beatenMy blood was spilled everywhereAnd as I sank down to the bottomand my life began to fade,you opened up your eyesout beyond the breaking point And as we gaze into the heavenswhere we dwell among the trees,you're always with me here beyond the breaking point _____________ Music and lyrics by Wells Hanley ©2021 Singers: Laura Ann Singh at www.lauraannsingh.com and Rei Alvarez at www.reialvarez.com https://www.iwrotethissongforyou.com/ https://www.patreon.com/iwrotethissongforyou NOTES: Currently, there is limited research on the factors that correlate with detransition and the percentage of individuals who chose to detransition. Of the available studies, methods and definitions vary, suggesting a need to establish standardized criteria in the future. Five studies are mentioned below. One concludes, of 17,151 who identify as transgender and gender diverse people, 13.1% reported a history of detransition or going back to living as their sex assigned at birth. Another concludes that only 0.2-0.3% of patients expressed post-operative regret and requested reversal surgery. In another study, 6.9% of patients detransitioned. Additional research is necessary to understand these phenomena more fully. Boyd, I.; Hackett, T.; Bewley, S. Care of Transgender Patients: A General Practice Quality Improvement Approach. Healthcare 2022, 10, 121. https://doi.org/10.3390/healthcare100 10121 Hall, R., Mitchell, L., & Sachdeva, J. (2021). Access to care and frequency of detransition among a cohort discharged by a UK national adult gender identity clinic: Retrospective case-note review. BJPsych Open, 7(6), E184. doi:10.1192/bjo.2021.1022 Littman L. Individuals Treated for Gender Dysphoria with Medical and/or Surgical Transition Who Subsequently Detransitioned: A Survey of 100 Detransitioners. Arch Sex Behav. 2021 Nov;50(8):3353-3369. doi: 10.1007/s10508-021-02163-w. Epub 2021 Oct 19. PMID: 34665380; PMCID: PMC8604821. Narayan SK, Hontscharuk R, Danker S, Guerriero J, Carter A, Blasdel G, Bluebond-Langner R, Ettner R, Radix A, Schechter L, Berli JU. Guiding the conversation - types of regret after gender-affirming surgery and their associated etiologies. Ann Transl Med 2021;9(7):605. doi: 10.21037/atm-20-6204. Turban JL, Loo SS, Almazan AN, Keuroghlian AS. Factors Leading to “Detransition” Among Transgender and Gender Diverse People in the United States: A Mixed-Methods Analysis. LGBT Health. 2021 May-Jun;8(4):273-280. doi: 10.1089/lgbt.2020.0437. Epub 2021 Mar 31. PMID: 33794108; PMCID: PMC8213007. GIVE US A HAND! Become our patron: https://www.patreon.com/ThisJungianLife RESOURCES: Learn to Analyze your own Dreams: https://thisjungianlife.com/enroll/
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