POPULARITY
Categories
Monty Nero the acclaimed creator of Death Sentence (Titan Comics) and Marvel's Hulk & X-Men is back to tear into the megacity shadows with the Kickstarter of Chrome Roses: Cyberpunk Trilogy Book 2! We're returning to The Tract, a rain-slicked dystopian metropolis where detective Kramm and punk vigilante Teo battle viruses, corporate corruption, and tech billionaires who literally own your emotions. Book 1 set the stage… now Book 2 cranks the stakes to a whole new level! In this interview, Monty drops: How Book 2 builds on the chaos and intrigue of Book 1 Secrets of crafting noir cyberpunk worlds that hit hard Art style evolutions and the darker tones of this chapter Kickstarter campaign exclusives for returning and new backers Hints at where the trilogy is heading
One of the most common dilemmas in urologic oncology: what do you do when a patient has T1 disease in both the bladder and the ureter? In the final episode of the 2025 NMIBC Creator Weekend™ series, Dr. Vignesh Packiam, Dr. Mark Tyson and Dr. Sarah Psutka share how they approach complex bladder cancer cases with upper tract involvement. --- This podcast is supported by: Ferring Pharmaceuticalshttps://ad.doubleclick.net/ddm/trackclk/N2165306.5658203BACKTABLE/B33008413.420220578;dc_trk_aid=612466359;dc_trk_cid=234162109;dc_lat=;dc_rdid=;tag_for_child_directed_treatment=;tfua=;gdpr=${GDPR};gdpr_consent=${GDPR_CONSENT_755};gpp=${GPP_STRING_755};gpp_sid=${GPP_SID};ltd=;dc_tdv=1 --- SYNPOSIS The doctors discuss complex bladder cancer cases, sequencing treatments for patients with dual ureteral and bladder T1 disease, the impact of cystectomy on quality of life, and the use of blue light cystoscopy and intravesical therapy. They also delve into the rise of bladder cancer in younger patients, considerations for low-grade intermediate-risk disease, and emerging therapeutic options. --- TIMESTAMPS 00:00 - Introduction05:52 - Upper Tract Positive Cytology Dilemma09:10 - Cystectomy Considerations15:55 - Developing Better Patient-Reported Outcomes20:26 - Challenges with New Therapeutics26:31 - Deescalating Treatment for Low-Grade Cancer33:29 - Closing Remarks --- RESOURCES CISTO Trialhttps://pubmed.ncbi.nlm.nih.gov/37980511/
In episode six of the Courage My Friends' season nine, we welcome impact strategist with Animikii, Indigenous Technology, Jeff Doctor, technology and human rights lawyer with Tekhnos Law and senior fellow with The Citizen Lab, Cynthia Khoo, senior researcher with the Canadian Centre for Policy Alternatives, Hadrian Mertins-Kirkwood. We discuss Canada's accelerated approach to artificial intelligence and the mobilization of civil society groups against it, multiple impacts of largely unregulated AI on people, planet and democracy, Indigenous perspectives on data sovereignty and digital colonialism and the meaning of AI beyond the hype. Reflecting on the government's accelerated AI development, Mertins-Kirkwood says: "There's definitely a distinct moment that's happening right now. A particular hype cycle, a push to adopt this current iteration of 'artificial intelligence', whatever that means … The question is why are we doing it. The way that the federal government in particular talks about AI is frankly very ideological … We need to adopt it for its own sake, independent of what that actually means … We're just kind of rushing without having a clear sense of where we're going." On civil society's objection to the "national sprint" consultation on AI, Khoo says: "...As people who are familiar with this field and topic … we're kind of appalled … AI has spread through so many spheres of society, it's not just a tech issue anymore, it's a whatever issue you care about … This 30-day "sprint" with leading language and incredibly narrow scoping from our government, it's frankly embarrassing. And just shows they're not really taking seriously the … empirically demonstrated … harms of AI and what's really at stake for everyone across the country. '" On the subject of data sovereignty, Doctor says: "Every technology has politics, Every technology is a product of its time … And enter this current moment where this magic bean of AI, this bundle of excuses comes together, that, oh we have to extract more, we have to mine more, we have to use more energy. As an Indigenous person this is nothing new to me … Indigenous territories, lands and peoples as sacrifice zones … for the greater good or for national sovereignty … Who's national sovereignty?" About today's guests: Jeff Doctor is a Cayuga Nation citizen from Six Nations of the Grand River Territory. As an Impact Strategist with Animikii, Jeff works with Indigenous Peoples across Turtle Island to develop web applications that support their self-determination and digital sovereignty. Jeff also volunteers with Protect the Tract: a Haudenosaunee grassroots project that promotes healthy land stewardship of the Haldimand Tract, and is an artist-in-residence at the University of Toronto as a member of the Akni:ho'gwa:s Artist Collective.Jeff has an MA in sociology and a decade of experience supporting Indigenous data sovereignty from the ground up. His focus is improving practical Indigenous data governance through advocacy, counter-mapping, and building appropriate, ethical software that helps Indigenous Peoples get their land, cash, and data back. Cynthia Khoo is a technology and human rights lawyer at Tekhnos Law, and a senior fellow at the Citizen Lab (University of Toronto). Previously, she was a senior associate at Georgetown Law's Center on Privacy & Technology in Washington, DC. Cynthia's legal practice, research, and expertise focuses on how the Internet and emerging technologies impact the human rights of historically marginalized groups, in particular their rights to privacy, equality, and freedom of expression. She holds a J.D. from the University of Victoria and LL.M. (Law and Technology) from the University of Ottawa, where she worked as junior counsel at and represented the Samuelson-Glushko Canadian Internet Policy and Public Interest Clinic (CIPPIC) as an intervener in cases before the Supreme Court of Canada. Hadrian Mertins-Kirkwood is a senior researcher with the Canadian Centre for Policy Alternatives, where he focuses on climate, artificial intelligence and economic policy. Read the OPEN LETTER to the Minister of Artificial Intelligence and Digital Innovation from civil society organizations and individuals opposing "National Sprint" consultation on AI strategy Individual and Organizations can sign onto the Open Letter, that has been re-opened for signatures, here. Transcript of this episode can be accessed at georgebrown.ca/TommyDouglasInstitute. Image: Cynthia Khoo, Jeff Doctor, Hadrian Mertins-Kirkwood / Used with permission. Music: Ang Kahora. Lynne, Bjorn. Rights Purchased. Intro Voices: Ashley Booth (Podcast Announcer); Bob Luker (Tommy) Courage My Friends podcast organizing committee: Chandra Budhu, Ashley Booth, Resh Budhu. Produced by: Resh Budhu, Tommy Douglas Institute and Breanne Doyle, rabble.ca. Host: Resh Budhu.
In this podcast we make the case for the importance of traditional aesthetics, art, and music in worship as a witness to God's beauty and transcendence. This is a presing question in an era where churches often embrace a more casual, consumer-oriented style.
1Link to get your sticker for the gospel presentation that Nate explained: https://www.redbubble.com/i/sticker/The-Fall-Gospel-Illustration-Small-by-tgistore/165427460.EJUG5 A youtube on how to use the presentation: https://linktr.ee/thegospelinitiative Why does open-air evangelism get put on the shelves in churches and academic institutions? · Open-air evangelism covers many different types of evangelism: o Open-air preaching o One-on-one conversation o Tract distribution o Bible distribution 2. What evangelism is not: When I say evangelism, I don't mean doing good things like feeding the needy, inviting people to church, and building a wheelchair ramp. (more on this later on in the podcast. ) · These things can be a means to an end. That gets us to a place to do evangelism, but they are not evangelism. · Evangelism is sharing or proclaiming the good news: God is our creator, we are sinful, Jesus came to resolve our issues, and we must repent and believe. 3. Educational institutions are looking for those who have the gift of teaching. 4. Eph 4:11 difference between teacher and evangelist 5. Most who are evangelists do not seek an education this way a. Here is why we should seek an education: I. We have been given the most important message, and we must be able to articulate it on a very high level as best as we can with the intelligence that God has given us. 6. What is the role of the Seminary and the church? 7. Most churches do not prioritize evangelism, and many will never have an open-air preacher or do open-air evangelism because their view of evangelism is not entirely accurate according to the Bible. 8. Finally, how can this time help someone understand evangelism rightly, see the role of academia, and the role of the church? Review: What is evangelism? What is the role of academia? What is the role of the church?
This week, Alexa chats with the brilliant Ian Howell to explore how we really hear the singers we work with. From psychoacoustics and functional listening to timbre, bias and intention, Ian unpacks the hidden processes behind vocal perception—and how understanding them can transform the way we teach. A deep, fascinating conversation for any singing teacher wanting sharper ears and smarter tools. WHAT'S IN THIS PODCAST? 1:53 What is psychoacoustics?5:28 How is sound perceived by us?12:38 What impacts the way we perceive sound?20:46 Separating function from bias25:48 Belt scenario35:36 How do singers hear themselves?40:59 How to listen and observe with skill1:05:27 The relationship between intent and perception1:15:15 Using spectrograms1:19:57 The way Ian teachesAbout the presenter HERERELEVANT MENTIONS & LINKSHearing Singing - A Guide to Functional Listening and Voice Perception by Ian HowellJohan SundbergThe Acoustics of the Singing Voice by Johan SundbergScience of the Singing Voice by Johan SundbergIngo Titze‘Goodbye Yellow Brick Road' by Sarah BareillesJeannie LoVetriFeldenkraisSinging Teachers Talk Podcast - Ep.63 Developing a Singer's Self Awareness and Clarifying Intention with Robert SussumaCornelius ReidVoce VistaAdvice for Young Musicians by Ian HowellStructure of Singing by Richard Miller ABOUT THE GUESTDr. Ian Howell is the Founder and Chief Educator of the Embodied Music Lab, offering professional development and consulting for musicians and teachers. He is the author of Advice for Young Musicians (2023) and Hearing Singing: A Guide to Functional Listening and Voice Perception (2025). From 2013–2023, Ian served on the voice faculty at the New England Conservatory, directing the graduate voice pedagogy program and leading research in the NEC Voice and Sound Analysis Lab, where he and his students presented widely and contributed vital work during the SARS-CoV-2 pandemic.SEE FULL BIO HEREWebsite
PThis Tract provides pastoral and practical guidance for incorporating ancient prayer practices of Morning and Evening Prayer into lives dominated by digital distractions and a fast-paced, always-on culture.
Morning Prayer (rejoicing in the Lord, salvation, digestive tract issues) #prayer #morningprayer #pray #jesus #god #holyspirit #aimingforjesus #healing #peace #love #bible #joy #rejoice #strength #digestivehealth#salvationThank you for listening, our heart's prayer is for you and I to walk daily with Jesus, our joy and peace aimingforjesus.com YouTube Channel https://www.youtube.com/@aimingforjesus5346 Instagram https://www.instagram.com/aiming_for_jesus/ Threads https://www.threads.com/@aiming_for_jesus X https://x.com/AimingForJesus Tik Tok https://www.tiktok.com/@aiming.for.jesus
Invité : - Olivier Rey, philosophe, pour Défécondité chez Gallimard, dans la collection Tract Hébergé par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.
Who owns the Holy Land? Israel? Palestine? God says that He gave from the Euphrates River to the Mediterranean Sea to Israel.
Are you ready for the evolving treatment paradigm in HER2-positive gastroesophageal adenocarcinoma (GEA) and biliary tract cancer (BTC)? Credit available for this activity expires: 10/24/27 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/her2-positive-gastroesophageal-adenocarcinoma-and-biliary-2025a1000sr3?&ecd=bdc_podcast_libsyn_mscpedu
A true life story tract called, "Living Life In The Fast Lane!" Is that how you are living? Speed, alcohol, and fast motorcycles do not produce happiness, but harm. This young man found that out, but he also found the One who could brake his bondage and give him a true abundant life. Have you found this One?
The true life story of Ken Miller. He fell through the ice when ice fishing. His intoxicated relative fell out of the boat while fishing, and could not swim. His barn was stuck by lightning, and was on fire. God was trying to get his attention, and God is trying to get your attention, too!
Micah McCurry is an evangelist & director of Bible Tracts, Inc., a ministry with a faith-driven commitment to share the Gospel far and wide with excellence. He's host of the radio program, Bible Tract Echoes. This broadcast explores why sharing our faith seems so difficult, yet on the other hand, why you should be excited to do it. For example, there are various things you can incorporate that can help along the way beginning with your personal testimony—your story! Remember, no one can tell your story quite like you can. You'll also learn how you can respectfully take conversation from the natural to the supernatural. Then there's the issue of sharing Bible tracts. Does that seem rather old-fashioned? Micah understands that sentiment. However, as he noted, like seeds, tracts need to be planted and Bible Tracts, Inc., can help you do that by supplying various types of tracts, even some for law enforcement and EMS personnel. So supercharge your personal evangelism efforts by listening to this edition of Crosstalk and learn more, including details about an exciting project: an autobiography of Bible Tracts, Inc., founder, Paul Levin.
Micah McCurry is an evangelist & director of Bible Tracts, Inc., a ministry with a faith-driven commitment to share the Gospel far and wide with excellence. He's host of the radio program, Bible Tract Echoes. This broadcast explores why sharing our faith seems so difficult, yet on the other hand, why you should be excited to do it. For example, there are various things you can incorporate that can help along the way beginning with your personal testimony—your story! Remember, no one can tell your story quite like you can. You'll also learn how you can respectfully take conversation from the natural to the supernatural. Then there's the issue of sharing Bible tracts. Does that seem rather old-fashioned? Micah understands that sentiment. However, as he noted, like seeds, tracts need to be planted and Bible Tracts, Inc., can help you do that by supplying various types of tracts, even some for law enforcement and EMS personnel. So supercharge your personal evangelism efforts by listening to this edition of Crosstalk and learn more, including details about an exciting project: an autobiography of Bible Tracts, Inc., founder, Paul Levin.
In this podcast episode, Amit Mahipal, MD, MPH, and Shubham Pant, MD, discuss new and emerging therapies for the personalized care of patients with HER2-positive gastroesophageal adenocarcinoma (GEA) and biliary tract cancer (BTC), including:Brief overview of BTC and GEAApproved HER2-directed therapies for BTC and GEA and their mechanisms of actionEfficacy and toxicities of the approved agents and optimal management strategiesKey ongoing trials of HER2-directed therapies in BTC and GEAChallenges faced by healthcare professionals in the management of patients with BTC and/or GEA PresentersAmit Mahipal, MD, MPHDirector, Gastrointestinal Medical Oncology ProgramRuth and Donald Goodman Endowed Chair in GI OncologyProfessor of Medicine, Senior Attending PhysicianUniversity Hospitals Siedman Cancer CenterCase Comprehensive Cancer CenterCase Western Reserve UniversityCleveland, OhioShubham Pant, MDProfessorDepartment of Gastrointestinal (GI) Medical OncologyDepartment of Investigational Cancer TherapeuticsDirector of Clinical ResearchAssociate Director for Early Phase Drug DevelopmentSheikh Ahmed Bin Zayed Al Nahyan CenterMD Anderson Cancer CenterHouston, TexasLink to full program:https://bit.ly/3KL2ank Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
In this episode, James talks with Nat Sahlstrom, Chief Energy Officer at Tract, a data center developer enabling the next generation of digital infrastructure. Nat shares his unconventional journey from Seattle's punk rock scene to leading energy strategy at Amazon and now Tract. With over two decades in energy, he brings deep insight into the intersection of data center growth, power planning, and sustainable infrastructure.They explore the critical challenges and opportunities facing the energy system in the age of hyperscale AI. Nat discusses his experience building one of the world's largest corporate renewable portfolios at Amazon and how Tract is addressing the power, land, and social license hurdles confronting data center developers today. He advocates for master-planned campuses as the key to responsible, scalable digital infrastructure and unpacks why the U.S. needs a World War II-level mobilization to meet future load demand.How hyperscaler energy needs are reshaping utility planning and permitting.The shift from back-office energy functions to front-page headlines.Why social license and stakeholder alignment are critical to infrastructure success.The case for horizontal and vertical integration in data center development.This episode is a must-listen for anyone thinking about where power, policy, and AI converge.Paces helps developers find and evaluate the sites most suitable for renewable development. Interested in a call with James, CEO @ Paces?
What is causing all of these children to shoot, stab, and beat up other people - even the elderly?
Located in the heart of Clear Brook, Virginia, Russell Ridge Farm Market is more than just a new addition to the region's agritourism scene—it's a testament to family legacy, community spirit, and the power of reinvention. In this episode of “The Valley Today,” host Janet Michael, joined by Winchester-Frederick County Tourism's Justin Kerns, sits down with Travis Russell to uncover the remarkable journey behind this burgeoning family farm market. A Family Affair Born of Adversity The story of Russell Ridge Farm Market is rooted in resilience. As Travis recounts, the Russell family has been farming in Clear Brook for three generations, primarily focusing on row crops like corn, soybeans, and wheat. But when a severe drought struck just after the family acquired a new property in 2023, the Russells faced a pivotal moment. “We were in the garage one evening, wondering what we were going to do,” Travis recalls. The answer? Embrace agritourism and open their land to the community. What began as a last-minute idea—cutting a corn maze into a field that wouldn't yield a profitable crop—quickly blossomed into a local sensation. The community rallied, and the Russells realized they had tapped into a growing desire for authentic, family-friendly farm experiences. Building a Community Hub Now entering its second season, Russell Ridge Farm Market has expanded both its offerings and its ambitions. The new barn, a labor of love still under construction, will soon house not only the market's homemade goods and crafts but also a dedicated event space for birthday parties, showers, and corporate gatherings. The market's focus remains on creating a welcoming environment for families, with attractions like a meticulously planned corn maze, hayrides, a pedal tractor track, and an ever-evolving playground. Travis emphasizes the importance of providing children with the kind of outdoor, hands-on experiences he cherished growing up—something increasingly rare in today's world. “It's so exciting to watch kids have the time of their life running around on a playground and through the corn maze,” he says. Events like the annual corn maze race, pumpkin painting, and the wildly popular “Tract or Treat” (a farm-themed twist on trunk-or-treat) have become community favorites. Collaboration Over Competition One of the most striking themes of the conversation is the spirit of collaboration among local farmers. Rather than competing, area farm markets support each other—sharing advice, produce, and even event ideas. “You'd think it would be really competitive, but it's not,” Justin notes. “The more you have, the more people come.” This camaraderie extends to sourcing local goods, with the Russells selling apples and pumpkins from neighboring farms and offering a range of homemade treats, crafts, and family recipes. Preserving Farmland, Preserving Heritage Beyond the fun and festivities, Russell Ridge Farm Market represents a deeper mission: preserving farmland in the face of development. As Travis and Justin discuss, once farmland is lost to housing, it rarely returns. By diversifying into agritourism, the Russells are not only sustaining their own family's legacy but also contributing to the broader effort to keep rural spaces alive for future generations. A Place Where Everyone Belongs The conversation is peppered with personal anecdotes—Janet's family ties to the Russells, memories of chocolate pies at holiday dinners, and the small-town quirks of sharing a last name with half the county. These stories underscore the market's role as a gathering place, where neighbors become friends and traditions are both honored and created anew. Plan Your Visit Russell Ridge Farm Market is open Saturdays and Sundays through the end of October, with special Friday night events like the Moonlit Hay Ride and Flashlight Corn Maze. Admission is $10 (kids two and under are free), covering unlimited access to all attractions. The market accepts both cash and credit, and there's plenty of parking for visitors. For more information, follow Russell Ridge Farm Market on Facebook and Instagram. Russell Ridge Farm Market is more than a response to a tough year—it's a celebration of family, community, and the enduring value of local agriculture. As Travis puts it, “My goal is to keep something on the farm for generations to come.” Thanks to the Russells' vision and the community's support, that future looks bright indeed. Visit the Winchester-Frederick County tourism website for a full calendar of local farm markets and events.
In an age defined by radical individualism, democratic consensus, and widespread institutional distrust, the concept of apostolic succession presents a profound challenge to modern sensibilities. Bishop Kevin considers new models for a new time
Due to a glitch inthe system the closing prayer for the Pod Tract is found in this post
In this episode of the Hunting Gear Podcast, host Dan Johnson speaks with John LaCorte from Tract Optics about preparing for the hunting season, overcoming personal challenges in archery, and the evolution of Track Optics as a direct-to-consumer brand. They discuss the importance of product quality, customer feedback, and the expansion of their product lines, including spotting scopes and the Impact Ballistics Program. The conversation emphasizes the brand's commitment to providing high-quality optics at competitive prices while maintaining strong customer engagement.takeaways John LaCorte is excited for the upcoming hunting season after overcoming a serious injury. The psychological impact of not being able to bow hunt can be significant. Track Optics focuses on providing value by cutting out the middleman. The company has not raised prices despite industry challenges like tariffs. Customer feedback directly influences product development at Track Optics. The demand for higher magnification scopes is increasing among older hunters. Track Optics offers a lifetime warranty on all products. The Impact Ballistics Program helps users understand their reticle and bullet drop. Quality control is a priority, with attention to detail in every product. Direct communication with customers is a key aspect of Track Optics' business model. Learn more about your ad choices. Visit megaphone.fm/adchoices
In this episode of the Hunting Gear Podcast, host Dan Johnson speaks with John LaCorte from Tract Optics about preparing for the hunting season, overcoming personal challenges in archery, and the evolution of Track Optics as a direct-to-consumer brand. They discuss the importance of product quality, customer feedback, and the expansion of their product lines, including spotting scopes and the Impact Ballistics Program. The conversation emphasizes the brand's commitment to providing high-quality optics at competitive prices while maintaining strong customer engagement.takeawaysJohn LaCorte is excited for the upcoming hunting season after overcoming a serious injury.The psychological impact of not being able to bow hunt can be significant.Track Optics focuses on providing value by cutting out the middleman.The company has not raised prices despite industry challenges like tariffs.Customer feedback directly influences product development at Track Optics.The demand for higher magnification scopes is increasing among older hunters.Track Optics offers a lifetime warranty on all products.The Impact Ballistics Program helps users understand their reticle and bullet drop.Quality control is a priority, with attention to detail in every product.Direct communication with customers is a key aspect of Track Optics' business model.
In this episode of the Hunting Gear Podcast, host Dan Johnson speaks with John LaCorte from Tract Optics about preparing for the hunting season, overcoming personal challenges in archery, and the evolution of Track Optics as a direct-to-consumer brand. They discuss the importance of product quality, customer feedback, and the expansion of their product lines, including spotting scopes and the Impact Ballistics Program. The conversation emphasizes the brand's commitment to providing high-quality optics at competitive prices while maintaining strong customer engagement.takeaways John LaCorte is excited for the upcoming hunting season after overcoming a serious injury. The psychological impact of not being able to bow hunt can be significant. Track Optics focuses on providing value by cutting out the middleman. The company has not raised prices despite industry challenges like tariffs. Customer feedback directly influences product development at Track Optics. The demand for higher magnification scopes is increasing among older hunters. Track Optics offers a lifetime warranty on all products. The Impact Ballistics Program helps users understand their reticle and bullet drop. Quality control is a priority, with attention to detail in every product. Direct communication with customers is a key aspect of Track Optics' business model. Learn more about your ad choices. Visit megaphone.fm/adchoices
Jeff Smith and Carson Odegard sit down with waterfowl historian Yancey Forest-Knowles to unpack the Sacramento–San Joaquin Delta—its island clubs, levees and tides, and the public access that still lets you chase mallards and specks on big water today.What you'll hearHow the Delta was built — from early private island claims and hand-built levees to today's twin pressures of saltwater intrusion and export pumping.Club lore & big names — Twitchell Island's first club (1880), Venice and Mandeville's eras, and the “Mallard Hole” stories tied to Barron Hilton and Hollywood guests.Flood risk is real — why peat islands subside and how Jones Tract's 2004 failure floated a clubhouse away.Public opportunity — boat-in spots and state-permitted floating blinds at Frank's Tract (plus Big Break, Stone Lakes, Decker & more), and the on-water etiquette that keeps it working.Access rules that matter — anchor next to levees to hunt, but don't set foot on them.Today's mix of ag & restoration — CWA ownership on Quimby and habitat work across Medford, Sherman, and sister islands.From 19th-century market hunts to modern floating blinds, this one maps the Delta's history and gives practical pointers for anyone looking to do it right on big water.
Featuring perspectives from Dr Haley Ellis and Dr James J Harding, including the following topics: Introduction: Is Biliary Tract Cancer (BTC) the New Non-Small Cell Lung Cancer? … Why? (0:00) Case: A woman in her mid 70s with metastatic cholangiocarcinoma receives first-line gemcitabine/cisplatin with durvalumab — Warren S Brenner, MD (8:42) Case: A man in his late 70s with metastatic biliary cancer (HER2 IHC 2+) discontinues first-line chemotherapy/immunotherapy because of exacerbation of Crohn's disease — Neil Morganstein, MD (17:48) Case: A man in his early 70s with metastatic cholangiocarcinoma (FGFR2 rearrangement) receives gemcitabine/oxaliplatin with durvalumab and experiences a rapid clinical decline — Kimberly Ku, MD (27:14) Case: A woman in her late 40s with Stage IV recurrent cholangiocarcinoma (FGFR2 rearrangement) receives pemigatinib — Justin Peter Favaro, MD, PhD (40:15) Case: A woman in her early 60s with HER2-positive cholangiocarcinoma develops metastatic disease during adjuvant capecitabine therapy — Dr Morganstein (46:09) CME information and select publications
Dr Haley Ellis and Dr James J Harding review actual patient cases and summarize clinical trial findings regarding the treatment of biliary tract cancers. CME information and select publications here.
Dr Haley Ellis and Dr James J Harding review actual patient cases and summarize clinical trial findings regarding the treatment of biliary tract cancers. CME information and select publications here.
Dr Haley Ellis and Dr James J Harding review actual patient cases and summarize clinical trial findings regarding the treatment of biliary tract cancers. CME information and select publications here.
Lorenza Rimassa, MD - Shifting the Paradigm in Biliary Tract Cancers: Contemporary Data and Decision-Making
Lorenza Rimassa, MD - Shifting the Paradigm in Biliary Tract Cancers: Contemporary Data and Decision-Making
Lorenza Rimassa, MD - Shifting the Paradigm in Biliary Tract Cancers: Contemporary Data and Decision-Making
Lorenza Rimassa, MD - Shifting the Paradigm in Biliary Tract Cancers: Contemporary Data and Decision-Making
Energetic Health Institute Radio with Angela Bulaga CHN – Brain fog, fatigue, GI issues (gas, bloating, nausea, vomiting, constipation, diarrhea). Oral thrush (white patches in the mouth and throat, soreness, and in the corners of the mouth), vaginal yeast infections (itching, burning, and discharge), jock itch, and anal itching. Athletes' foot, skin rashes (Eczema; Red, moist, or scaly rash, sometimes in...
Energetic Health Institute Radio with Angela Bulaga CHN – Brain fog, fatigue, GI issues (gas, bloating, nausea, vomiting, constipation, diarrhea). Oral thrush (white patches in the mouth and throat, soreness, and in the corners of the mouth), vaginal yeast infections (itching, burning, and discharge), jock itch, and anal itching. Athletes' foot, skin rashes (Eczema; Red, moist, or scaly rash, sometimes in...
In today's episode, we had the opportunity to speak with Arndt Vogel, MD, about the European Commission's (EC's) July 2025 marketing authorization of zanidatamab-hrii (Ziihera) for the treatment of adult patients with previously treated, unresectable, locally advanced or metastatic HER2-positive biliary tract cancer. Dr Vogel is a faculty member at the University of Toronto Institute of Medical Science, a scientist at the Toronto General Hospital Research Institute, and a medical oncologist at the UHN–Princess Margaret Cancer Centre in Canada. In our exclusive interview, Dr Vogel highlighted the clinical importance of this decision, emphasizing that it represents a significant advancement for a molecularly defined subgroup of patients with limited treatment options and historically poor outcomes. He explained that biliary tract cancers, including cholangiocarcinoma, are associated with high recurrence rates and poor survival, even in patients who undergo curative-intent surgery. For patients in the advanced setting, second-line chemotherapy offers modest clinical benefit, with objective response rates of approximately 6%, a median progression-free survival of approximately 3 months, and a median overall survival of approximately 12 months. Vogel discussed the data supporting the EC's approval, which was based on findings from the phase 2b HERIZON-BTC-01 trial (NCT04466891)—the largest study conducted to date evaluating HER2-directed therapy in this patient population. In the trial, at a median follow-up of 21.9 months, patients with centrally confirmed HER2-positive tumors (n = 80) who received zanidatamab achieved a confirmed objective response rate (cORR) of 41.3% (95% CI, 30.4-52.8). The median duration of response was 14.9 months (95% CI, 7.4-not reached), and the median overall survival reached 15.5 months (95% CI, 10.4-18.5).
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/AAPA information, and to apply for credit, please visit us at PeerView.com/VZA865. CME/MOC/AAPA credit will be available until June 29, 2026.Refining Treatment Models For Biliary Tract Cancer Aligning Practice With Rapidly Evolving Evidence on Immunotherapy & Targeted Platforms In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and Cholangiocarcinoma Foundation. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent medical education grants from Incyte Corporation, Jazz Pharmaceuticals, Inc., Servier Pharmaceuticals LLC, and Taiho Oncology, Inc.Disclosure information is available at the beginning of the video presentation.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/AAPA information, and to apply for credit, please visit us at PeerView.com/VZA865. CME/MOC/AAPA credit will be available until June 29, 2026.Refining Treatment Models For Biliary Tract Cancer Aligning Practice With Rapidly Evolving Evidence on Immunotherapy & Targeted Platforms In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and Cholangiocarcinoma Foundation. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent medical education grants from Incyte Corporation, Jazz Pharmaceuticals, Inc., Servier Pharmaceuticals LLC, and Taiho Oncology, Inc.Disclosure information is available at the beginning of the video presentation.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/AAPA information, and to apply for credit, please visit us at PeerView.com/VZA865. CME/MOC/AAPA credit will be available until June 29, 2026.Refining Treatment Models For Biliary Tract Cancer Aligning Practice With Rapidly Evolving Evidence on Immunotherapy & Targeted Platforms In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and Cholangiocarcinoma Foundation. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent medical education grants from Incyte Corporation, Jazz Pharmaceuticals, Inc., Servier Pharmaceuticals LLC, and Taiho Oncology, Inc.Disclosure information is available at the beginning of the video presentation.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/AAPA information, and to apply for credit, please visit us at PeerView.com/VZA865. CME/MOC/AAPA credit will be available until June 29, 2026.Refining Treatment Models For Biliary Tract Cancer Aligning Practice With Rapidly Evolving Evidence on Immunotherapy & Targeted Platforms In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and Cholangiocarcinoma Foundation. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent medical education grants from Incyte Corporation, Jazz Pharmaceuticals, Inc., Servier Pharmaceuticals LLC, and Taiho Oncology, Inc.Disclosure information is available at the beginning of the video presentation.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/AAPA information, and to apply for credit, please visit us at PeerView.com/VZA865. CME/MOC/AAPA credit will be available until June 29, 2026.Refining Treatment Models For Biliary Tract Cancer Aligning Practice With Rapidly Evolving Evidence on Immunotherapy & Targeted Platforms In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and Cholangiocarcinoma Foundation. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by independent medical education grants from Incyte Corporation, Jazz Pharmaceuticals, Inc., Servier Pharmaceuticals LLC, and Taiho Oncology, Inc.Disclosure information is available at the beginning of the video presentation.
Biliary tract cancer (BTC) presents a complex puzzle for the interprofessional healthcare team. With its diverse subtypes and unique molecular features, diagnosis and treatment require a personalized approach. Stay ahead of the curve with insights from leading experts, Dr. Anjana Pillai and Dr. Rachna Shroff, as they explore the latest genomic research, targeted therapies, and emerging treatment strategies in this dynamic podcast. Listen now to hear the Multidisciplinary Task Force perspective and strategies to optimize patient care in this rapidly evolving landscape. Click here to claim your credit for this podcast:
With so many treatment modalities for upper tract urothelial carcinoma, how does new evidence inform optimal care? In this episode of BackTable Tumor Board, urologic oncologist Dr. Nirmish Singla (Johns Hopkins), medical oncologist Dr. Jeannie Hoffman-Censits (Johns Hopkins), and urologic oncologist Dr. Bogdana Schmidt discuss treatment and diagnosis of upper tract urothelial carcinoma (UTUC). --- This podcast is supported by: Ferring Pharmaceuticalshttps://ad.doubleclick.net/ddm/trackclk/N2165306.5658203BACKTABLE/B33008413.420220578;dc_trk_aid=612466359;dc_trk_cid=234162109;dc_lat=;dc_rdid=;tag_for_child_directed_treatment=;tfua=;gdpr=${GDPR};gdpr_consent=${GDPR_CONSENT_755};gpp=${GPP_STRING_755};gpp_sid=${GPP_SID};ltd=;dc_tdv=1 --- SYNPOSIS The discussion covers real-world UTUC cases, highlighting diagnostic challenges, treatment options, and evidence-based management strategies. They address scenarios ranging from localized to advanced UTUC, the role of systemic therapies, perioperative treatments, and the potential for novel approaches with immune checkpoint inhibitors. The episode underscores the evolving landscape of UTUC treatment and the importance of clinical trials and emerging biomarkers in improving patient outcomes. --- TIMESTAMPS 00:00 - Introduction 02:49 - Case Study 1: 66-Year-Old Male with UTUC11:19 - Case Study 2: 73-Year-Old Male with High-Grade Urothelial Carcinoma28:11 - Intravesical Chemotherapy Protocols30:44 - Case Study 3: 57-Year-Old Male with Recurrent Urothelial Cancer41:25 Clinical Trials and Emerging Treatments45:40 Case Study: 55-Year-Old Female with Bulky Lymphadenopathy 56:45 Concluding Remarks and Future Directions --- RESOURCES Society of Urologic Oncologyhttps://suonet.org/home.aspx
In this episode, we review the high-yield topic of Gastrointestinal Tract Histology from the Gastrointestinal section.Follow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets
Welcome to the emDOCs.net podcast! Join us as we review our high-yield posts from our website emDOCs.net.Today on the emDOCs cast with Rachel Bridwell, MD, and Brit Long, MD (@long_brit), we cover left ventricular outflow tract obstruction, or LVOTO. To continue to make this a worthwhile podcast for you to listen to, we appreciate any feedback and comments you may have for us. Please let us know!Subscribe to the podcast on one of the many platforms below:Apple iTunesSpotifyGoogle Play
TAKEAWAYSAre you an active follower of Christ or just a Sunday morning believer? Your children are watchingYou get to choose what your kids are going to be exposed toYou can't completely isolate your children from culture; you have to prepare them to serve in it somehowNo matter how old or how young you are, God hears your prayersChildren can absolutely lead people to Christ just as well as adults can
Welcome to another episode of the Oncology Brothers podcast! In this episode, Drs. Rohit and Rahul Gosain, both practicing community medical oncologists, continue their discussion on HER2-positive biliary tract cancer. They are joined by Dr. Shubham Pant from MD Anderson, who shares his expertise on this rapidly evolving field. In this episode, we cover: • The importance of HER2 testing in biliary tract cancers, including intrahepatic and extrahepatic cholangiocarcinomas and gallbladder cancers. • Who should be tested for HER2 positivity and how to classify HER2-positive disease. • The role of next-generation sequencing (NGS) and immunohistochemistry (IHC) in determining HER2 status. • Current treatment options for HER2-positive biliary tract cancer, including the latest clinical trials and approved therapies like trastuzumab deruxtecan and zanidatamab. • The significance of patient-centered decision-making and managing side effects associated with these treatments. • Insights into the potential for brain metastases in biliary tract cancer and the importance of ongoing surveillance. Join us as we delve into the latest data and strategies for managing HER2-positive biliary tract cancer, and stay tuned for our next episode where we will discuss side effects and management of these therapies. Accreditation/Credit Designation Physicians' Education Resource®, LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Physicians' Education Resource®, LLC designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Acknowledgment of Commercial Support This activity is supported by an educational grant from Jazz Pharmaceuticals, Inc. Link to gain CME credits from this activity: https://www.gotoper.com/courses/from-bench-to-bedside-paradigm-shifts-in-her2-metastatic-btc-treatment Follow us on social media: • X/Twitter: https://twitter.com/oncbrothers • Instagram: https://www.instagram.com/oncbrothers • Website: https://oncbrothers.com/ Don't forget to like, subscribe, and hit the notification bell for more updates from the Oncology Brothers!
Featuring perspectives from Dr Mitesh J Borad and Dr Amit Mahipal, including the following topics: Introduction (0:00) Targeted Therapeutic Approaches for Patients with Biliary Tract Cancers (BTCs) — Dr Mahipal (4:59) Integration of Immune Checkpoint Inhibitors into Current BTC Management — Dr Borad (32:16) CME information and select publications
Welcome to the Oncology Brothers podcast! In this episode, Drs. Rohit and Rahul Gosain are joined by Dr. Ghassan Abou-Alfa, a medical oncologist specializing in the hepatobiliary space at Memorial Sloan Kettering. Together, they explored the current treatment landscape of biliary tract cancer, focusing on the advancements in HER2-driven therapies. Key topics discussed included: • The evolution of treatment options for biliary tract cancer, including chemotherapy and immunotherapy. • The significance of genetic testing, including IDH1 mutations, FGFR alterations, and HER2 status. • The role of multidisciplinary collaboration in managing hepatobiliary cancers. • Insights into the latest clinical trials and emerging therapies for HER2-positive biliary tract cancer. Join us as we delve into the complexities of biliary tract cancer and the promising developments in HER2-targeted treatments. Don't forget to check out our next episode, where we will take a deeper dive into the data surrounding HER2 therapies and discuss management strategies for common side effects. YouTube: https://youtu.be/pGiU7JJGNOc Follow us on social media: • X/Twitter: https://twitter.com/oncbrothers • Instagram: https://www.instagram.com/oncbrothers • Website: https://oncbrothers.com/ Subscribe to stay updated on the latest in oncology! #OncologyBrothers #BiliaryTractCancer #HER2 #CancerTreatment #MedicalOncology #CME #Podcast
Perhaps it's no coincidence that an infusion of spinach leaves has evidently been used since ancient times to treat respiratory symptoms.