Podcasts about Laboratory

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Facility that provides controlled conditions in which scientific or technological research, experiments, and measurement may be performed.

  • 1,450PODCASTS
  • 2,837EPISODES
  • 41mAVG DURATION
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  • Oct 25, 2021LATEST
Laboratory

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Best podcasts about Laboratory

Show all podcasts related to laboratory

Latest podcast episodes about Laboratory

Answers TV Daily
Answers News: Who Says We Can Make a Universe?

Answers TV Daily

Play Episode Listen Later Oct 25, 2021 36:38


Raven attacks coffee drone; Harvard astronomy chair continues to assert absurdities; Chinese publish giant scorpion fossil Terropterus xiushanensis; Father details how LGBTQIA+ therapists harmed his son . . . and other stories reviewed during this October 25, 2021, broadcast of Answers News. - - - - - - - - - - - The fool says in his heart, “There is no God.” They are corrupt, they do abominable deeds; There is none who does good. - - - - - - - - - - - Psalm 14:1 Articles: Wanna see a raven launch an attack on a drone delivering coffee? (video included) https://notthebee.com/article/wanna-see-a-raven-attack-a-drone-delivering-coffee Was Our Universe Created in a Laboratory? https://www.scientificamerican.com/article/was-our-universe-created-in-a-laboratory/ Terrifying 3-Foot Scorpion Which Skewered Prey With Spines Found in China https://www.newsweek.com/3-foot-scorpion-skewered-prey-spines-found-china-terropterus-xiushanensis-1640232 Father details how his young son was convinced he was a 'transgender lesbian' https://www.christianpost.com/news/father-my-young-son-was-convinced-he-was-a-transgender-lesbian.html Christian parents fight back against trans policies in British primary schools https://www.christianpost.com/news/christian-parents-challenge-trans-policies-in-primary-schools.html Extinct Japanese wolf is the closest wild relative of dogs yet found https://newscientist.com/article/2294090-extinct-japanese-wolf-is-the-closest-wild-relative-of-dogs-yet-found/ T. rex with feathers: China's fossils are rewriting the dinosaur story https://newscientist.com/article/mg25133560-800-t-rex-with-feathers-chinas-fossils-are-rewriting-the-dinosaur-story/ Ohio college student 'angry' and 'scared' after 'cisgender men' installed radiator in dorms: 'Safe space' https://www.foxnews.com/us/oberlin-college-student-angry-cisgender-work-crew-radiators-safe-space - - - - - - - - - - - Image Credit: Agor2012 Getty # 1310155102 --- Send in a voice message: https://anchor.fm/answerstv/message Support this podcast: https://anchor.fm/answerstv/support

Voices from The Bench
187: Behind Every Great Dentist is an Amazing Lab: John & Jed Archibald

Voices from The Bench

Play Episode Listen Later Oct 25, 2021 65:18


They say behind every famous person is the true group that makes them famous. John Archibald has been the in-office dental technician to the famous Dr. Gordon Christensen (https://www.pccdental.com/). This gave John a chance to be on the forefront of a lot of new products and procedures. Seeing an opportunity to teach the lab industry, he started the country's only full time apprenticeship school. Raising his son Jed Archibald (https://www.archibalddigital.com/) in the school, Jed was soon teaching in the school and continuing the name in the industry as a leader with the development to the digital workflow. Clinicians Report (https://www.cliniciansreport.org/) Gro3X (https://www.gro3x.com/) is a dental supply, service and marketing company that was founded by Norbert Ulmer and their goal is to help dental labs, and especially small labs to lower their cost for supplies, provide business opportunities, and generate growth. Attend their upcoming Gro3X Gem Talks on November 5th in Charlotte, NC (https://www.gro3x.com/collections/family/products/gro3x-gem-talks). Gro3X Gem Talks is an all day marketing symposium in Ted-Talk style featuring some 10+ lab speakers as they share their most relevant and practical marketing techniques. We will hear from Sasha der Avanessian from Harvest Dental (https://harvestdental.com/), Anne Kelzer from AMK Dental Lab (https://www.facebook.com/people/AMK-Dental-Lab/100028120884702/), Frankie Acosta from AA Dental Design (https://www.aadentaldesign.com/) and Ricki Braswell from Beyond Coaching (https://www.transitionbeyond.com/) and former Co-Executive Director of the NADL. All of them will talk about real marketing as it is done in their own labs and businesses every day. Register now at gro3x.com to take advantage of their early bird special of only $95. Enter discount code VFTB for Voices from The Bench and receive an extra 10% discount, just because you listen to this Podcast. Whip Mix (https://www.whipmix.com/) offers you the ultimate in ease, material flexibility and unattended production with the Roland DGA DWX-52DCi (https://www.whipmix.com/products/roland-dwx-52dci/) milling machine. The popular mill's automatic disc changer expands your lab production and profit, using a 6-slot Automatic Disc Changer, 15-station Automatic Tool Changer and several other automated features. The DWX-52DCi dental milling machine now comes with performance visualization software and other intelligent updates. The 5-axis mill even knows which tool to automatically swap out when tools have reached their designated lifespan. Just power it on, let it go, and automatically and accurately mill numerous dental restoration jobs with complete unattended confidence. If you're interested in learning more about the Roland DGA DWX-52DCi, visit whipmix.com or call 800-626-5651. Have you seen the high prices of precious metal these days? They are close to record highs on gold and palladium. With those high precious metal prices, you are paying a high cost for your alloys. We know that you are using less Precious metal in your lab these days, but if you send in half of what you sent in 5 years ago ,your scrap return will be higher than it was 5 years ago ,because of the high PM prices . You owe it to yourself to find a trusted, reputable refining company. Look no further! Kulzer refining (https://www.kulzerus.com/en_us/en_us/heraeuspreciousmetalsrefining/scraprefining.aspx) has been tested, trusted and reputable for over 100 years. They burn, melt and assay all under one roof at their state-of-the-art refining facility in Wartburg Tennessee. They have doubled their production capacity to ensure your scrap return within 2 weeks. With all the non-precious material that has become present in today's restorations it is important that we ensure the assay sample is homogenous. At Kulzer (https://www.kulzerus.com/en_us/en_us/home_9/home.aspx), they take the extra step to X-ray the top and bottom after they melt the bar to make sure the precious metal percentages--- are the same. If not, copper is added until they are positive the bar is homogeneous. We know this step is very important to get a precise assay result. Their reimbursement to the customer is after our 10% refining fee. They have zero additional fees. If you need any free shipping containers, which contain a UPS prepaid, full insured label, please visit mydental360.com/refining or call the Director of Precious Metal Refining, Tony Circelli, directly at (914) 906-1843. Special Guests: Jed Archibald and John Archibald.

The Anatomy Nerd Podcast
Plastic and Reconstructive Surgery with Dr. Ross Sayadi

The Anatomy Nerd Podcast

Play Episode Listen Later Oct 25, 2021 50:30


Plastic and reconstructive surgery involves so much more than a little nip here and a little tuck there. In this episode, Dr. Ross Sayadi, a Plastic and Reconstructive Surgery Resident Physician at the University of California Irvine, tells his story of how he got into medical school, the research projects he has been involved in, and the various medical tools and inventions he has developed in the lab and at home that are now being used in practice with patients. We discuss the different kinds of plastic surgery, his research on micro/nanobubbles for tissue oxygenation and wound treatment, the iPhone app he created called OR Stencil, and so much more.You can connect with Dr. Sayadi on Instagram @rosssayadiSupport the show (https://www.patreon.com/theanatomynerdpodcast)

The Hoffman Podcast
S3E23: Linda & Charlie Bloom – Partnership as a Laboratory

The Hoffman Podcast

Play Episode Listen Later Oct 21, 2021 43:25


Linda and Charlie Bloom each did the Hoffman Process thirty years ago. The powerful transformations they experienced at the Process continue to be alive in them today. Charlie tells us how he learned of the freedom and joy in taking responsibility for his own life. Linda shares about grieving the image of 'parents charming,' the perfect parents she didn't get so that she could come to accept and honor the parents she did have. Listen in as Linda and Charlie offer decades of learning, experience, and insight around partnership as a laboratory. In their work, they guide clients to see relationships as a way to learn how to be in and grow into partnership, as well as a path to wellness. The Blooms originally became psychotherapists because they came from difficult families and wanted to understand what functional families look like. With that understanding, they could create a better family for their children. Along the same lines, they started working with couples after going through a rocky time themselves in their marriage.  More about the Blooms Married since 1972, Linda and Charlie Bloom have been working with groups, individuals, couples, and organizations since 1975. Their work is to support clients in enhancing the quality of their relationships and communication skills. Linda and Charlie both have Master's degrees in Clinical Social Work. They've lectured, led seminars, and provided consultation at universities and learning institutes nationally and internationally. The Blooms' organization, Bloomwork, is dedicated to promoting healthy, fulfilling, and successful relationships for individuals, couples, and organizations. Linda and Charlie have served as psychotherapists, marriage counselors, consultants, and seminar leaders since 1975. In addition to their academic and professional training, the Blooms' expertise in the field of relationships stems from experience in the crucible of their own committed partnership of over 52 years. The Blooms have written and published four books: Happily Ever After…and 39 Other Myths about Love: Breaking Through to the Relationship of Your Dreams, 101 Things I Wish I Knew When I Got Married: Simple Lessons to Make Love Last, Secrets of Great Marriages: Real Stories from Real Couples about Lasting Love, and That Which Doesn't Kill Us: How One Couple Became Stronger in the Broken Places.  Linda and Charlie offer many complimentary e-books as well as great content on YouTube. You can find out more about them at Bloomwork, and follow them on Facebook, Twitter, and Tumblr. As mentioned in this episode Enlightened Self-Interest You don't have to choose between your needs and your partner's needs or the relationship's needs. Everything you put into your relationship will come back to you. John Gottman of the Gottman Institute   Discover if the Process is right for you. Subscribe on Apple/iTunes

Father Bill W.
Tom Powers and His Great Experiment: The Man in His Laboratory

Father Bill W.

Play Episode Listen Later Oct 20, 2021 51:42


Tom Powers helped Bill Wilson write 12 Steps and 12 Traditions, AA Comes of Age, and the Second Edition of the Big Book. Bill was his mentor, friend, and sponsor. In his book Invitation to a Great Experiment, Tom takes 12 Step spirituality to greater depths than you're likely to find in any other recovery work as he explores three vital questions: Can God be known? Is there an experiment we can test to answer this question? And how can we know and do God's will? Fr. Bill interviews Matt D. who knew Tom well and is in charge of his All Addicts Anonymous archives. The series will explore the book and the man in depth. Show Notes: Invitation to a Great Experimentis out of print and costly on Amazon. However, it can be purchased affordably though through Matt D. at All Addicts Anonymous: click here: https://alladdictsanonymous.org/store/If finances are a problem, please write to AllAddictsAnonymous@Gmail.com/for a free electronic edition. The classic book Why Do Men Stupefy Themselves written by Leo Tolstoy is available here: https://en.wikisource.org/wiki/Why_Do_Men_Stupefy_Themselves%3F/ To support this podcast and to advance Two Way Prayer please click here: https://www.twowayprayer.org/donate-1/ Interested in joining a workshop? Check out all upcoming events on twowayprayer.org --- Support this podcast: https://anchor.fm/fatherbillw/support

Relaxing White Noise
Halloween White Noise 8 hours | Mad Scientist Laboratory Sounds

Relaxing White Noise

Play Episode Listen Later Oct 20, 2021 480:47


Join us in our mad scientist's laboratory, where we brew up some Halloween White Noise. This is Dr. Frankenstein's favorite ambient sound. It's the noise that played in Doc Brown's nursery when he was just a baby mad scientist. And Fringe's Walter Bishop can't sleep without playing this sound, along with someone singing Row, Row, Row Your Boat. Yes, this white noise is the sound for both aspiring and seasoned mad geniuses. Bring out your inner mad scientist with our Halloween White Noise. Check out the 10-Hour version on YouTube Contact Us for Partnership Inquiries Relaxing White Noise is the number one destination on YouTube for white noise and nature sounds to help you sleep, study or soothe a baby. With more than a billion views across YouTube and other platforms, we are excited to now share our popular ambient tracks on the Relaxing White Noise podcast. People use white noise for sleeping, focus, sound masking or relaxation. We couldn't be happier to help folks live better lives. This podcast has the sound for you whether you use white noise for studying, to soothe a colicky baby, to fall asleep or for simply enjoying a peaceful moment. No need to buy a white noise machine when you can listen to these sounds for free. Cheers to living your best life! DISCLAIMER: Remember that loud sounds can potentially damage your hearing. When playing one of our ambiences, if you cannot have a conversation over the sound without raising your voice, the sound may be too loud for your ears. Please do not place speakers right next to a baby's ears. If you have difficulty hearing or hear ringing in your ears, please immediately discontinue listening to the white noise sounds and consult an audiologist or your physician. The sounds provided by Relaxing White Noise are for entertainment purposes only and are not a treatment for sleep disorders or tinnitus. If you have significant difficulty sleeping on a regular basis, experience fitful/restless sleep, or feel tired during the day, please consult your physician. © Relaxing White Noise LLC, 2017. All rights reserved. Any reproduction or republication of all or part of this text/visual/audio is prohibited. --- Support this podcast: https://anchor.fm/relaxingwhitenoise/support

20-Minute Health Talk
Clinical trials and the blood brain barrier

20-Minute Health Talk

Play Episode Listen Later Oct 19, 2021 20:06


The COVID-19 vaccines have put a spotlight on the importance of clinical trials. During the early days of the pandemic in New York, researchers like John Boockvar, MD, had to shut down ongoing trials to contribute to the fight against the novel virus. Since, he has resumed his work investigating novel approaches to treating brain cancers. He has been internationally recognized for his research in brain tumors and stem cell biology throughout his 20-year career. He explains the importance of clinical trials, his connection with the inventor of mRNA technology, and his experience leading investigations into experimental treatments for glioblastomas — the deadliest form of brain cancer.   Meet the expert Dr. Boockvar is a world-renowned brain tumor expert. He is vice chair of neurosurgery and director of the Brain Tumor Center at Lenox Hill; and director of the Laboratory for Brain Tumor Biology and Therapy at the Feinstein Institutes for Medical Research.  Along with his fellow neurosurgeons, he was the subject of the highly-acclaimed Netflix docudrama in 2020, “Lenox Hill.” 

Physician NonClinical Careers
6 Important Assignments of a Hospital CMO

Physician NonClinical Careers

Play Episode Listen Later Oct 19, 2021 24:17


Today I discuss my work as chief medical officer. I spent 14 years as a senior hospital executive. There was a lot to like about that job. More than I can cover in one podcast episode. I presented the positive aspects of a hospital management career in Podcast Episode #20. But today, I'll focus on some of the specific projects I worked on and the directors who I worked with. I think it will give you a better idea of what a CMO does. I hope it will inspire you to consider a hospital management career. For those NOT considering such a career, you should listen anyway, because what I'll describe applies to a senior leadership position in almost any industry – even in your own business. I will start by listing the six assignments I want to describe today. Notice that I call them assignments because they represent a combination of the work with a specific department and its director, PLUS one or more of specific projects that we worked on together. For 2 of the 6, there was no distinct director to mention, for reasons I will explain when I get to those assignments. Here is the list of the 6 assignments… Leading the CME program, supporting the residency program start-up, and working with Lisa Zipsie, Director of Physicians Services. Selecting and implementing the first Quality Management Program, achieving Top 100 Hospital Status, and working with Mary Schore, QI Director. Implementing the hospital's first Lean Process Improvement Initiative and working with Stephanie Mitchell, Director of the Laboratory. Overseeing the implementation of physician order entry and the medication safety program and working with Jim Shafer, Pharmacy Director. Establishing the first hospitalist service. Recruiting physicians, purchasing local physician practices, and leading the medical group during its growth to the dominant multispecialty group in the county. For the details of each assignment, you must listen to the episode or read the transcript included in the show notes. You can find the show notes for today's episode at nonclinicalphysicians.com/assigments-of-a-hospital-cmo If you'd like to join my Nonclinical Mastermind Group, you can learn about it at nonclinicalphysicians.com/mastermind. Get an updated edition of the FREE GUIDE to 10 Nonclinical Careers at nonclinicalphysicians.com/freeguide. Get a list of 70 nontraditional jobs at nonclinicalphysicians.com/70jobs. Check out a FREE WEBINAR called Best Options for an Interesting and Secure Nonclinical Job at nonclinicalphysicians.com/freewebinar1

Voices from The Bench
186: Finding Balance in the Lab with John Wilson

Voices from The Bench

Play Episode Listen Later Oct 18, 2021 70:09


Check out A Very Dental Podcast: Shorts: Everyone Sucks at Their Job (except Elvis) (https://verydentalpodcast.com/episode/shorts-everyone-sucks-at-their-job-except-elvis) This week we welcome John Wilson from Sunrise Dental Laboratory (http://www.sunrisedentallab.com/) out in California to the podcast. He has been at this lab game for a while. Early on he saw the importance of putting his lab on the front line of implant restorations. John comes on the podcast to talk about his early days as a punk kid, mistakes he's made, and more importantly the lessons he has learned. It's just an added bonus that he shares the lessons in hope that he can prevent some others from making the same mistake. Whip Mix (https://whipmix.com/) is now providing its milling customers with Prima Milling Tools (https://whipmix.com/products/prima-milling-tools/), the high performance milling tools engineered specifically for Roland mills. This new tool range outperforms the competition. The results show not only that the tools last 29% longer than most others, their precision creates pin-point accuracy, ensuring a perfect fit for the patient. The uncoated tools save up to 40% per restoration over the market leaders, VISIT WHIPMIX.COM OR CALL (800) 626-5651 to get yours today! Gro3X (https://www.gro3x.com/) is a dental supply, service and marketing company that was founded by Norbert Ulmer and their goal is to help dental labs, and especially small labs to lower their cost for supplies, provide business opportunities, and generate growth. Attend their upcoming Gro3X Gem Talks on November 5th in Charlotte, NC (https://www.gro3x.com/collections/family/products/gro3x-gem-talks). Gro3X Gem Talks is an all day marketing symposium in Ted-Talk style featuring some 10+ lab speakers as they share their most relevant and practical marketing techniques. We will hear from Sasha der Avanessian from Harvest Dental (https://harvestdental.com/), Anne Kelzer from AMK Dental Lab (https://www.facebook.com/people/AMK-Dental-Lab/100028120884702/), Frankie Acosta from AA Dental Design (https://www.aadentaldesign.com/) and Ricki Braswell from Beyond Coaching (https://www.transitionbeyond.com/) and former Co-Executive Director of the NADL. All of them will talk about real marketing as it is done in their own labs and businesses every day. Register now at gro3x.com to take advantage of their early bird special of only $95. Enter discount code VFTB for Voices from The Bench and receive an extra 10% discount, just because you listen to this Podcast. Have you seen the high prices of precious metal these days? They are close to record highs on gold and palladium. With those high precious metal prices, you are paying a high cost for your alloys. We know that you are using less Precious metal in your lab these days, but if you send in half of what you sent in 5 years ago ,your scrap return will be higher than it was 5 years ago ,because of the high PM prices . You owe it to yourself to find a trusted, reputable refining company. Look no further! Kulzer refining (https://www.kulzerus.com/en_us/en_us/heraeuspreciousmetalsrefining/scraprefining.aspx) has been tested, trusted and reputable for over 100 years. They burn, melt and assay all under one roof at their state-of-the-art refining facility in Wartburg Tennessee. They have doubled their production capacity to ensure your scrap return within 2 weeks. With all the non-precious material that has become present in today's restorations it is important that we ensure the assay sample is homogenous. At Kulzer (https://www.kulzerus.com/en_us/en_us/home_9/home.aspx), they take the extra step to X-ray the top and bottom after they melt the bar to make sure the precious metal percentages--- are the same. If not, copper is added until they are positive the bar is homogeneous. We know this step is very important to get a precise assay result. Their reimbursement to the customer is after our 10% refining fee. They have zero additional fees. If you need any free shipping containers, which contain a UPS prepaid, full insured label, please visit mydental360.com/refining or call the Director of Precious Metal Refining, Tony Circelli, directly at (914) 906-1843. Special Guest: John Wilson.

Hopkins Biotech Podcast
My PhD- Joe Varriale

Hopkins Biotech Podcast

Play Episode Listen Later Oct 18, 2021 12:34


Joe is a fourth-year PhD candidate at the Johns Hopkins University School of Medicine in the Laboratory of Dr. J.N. and R.F. Siliciano. If you are a Hopkins Biotech Podcast follower,  you know Joe as the podcast co-director, producer and host. This time we have the pleasure to have him as a guest and to know more about his exciting career.His PhD thesis involves characterizing the reservoir of latently infected cells that render HIV infection a lifelong illness. In line with his Entrepreneurial mind set, Joe is a Fellow of the Commercialization Academy program at Johns Hopkins Technology Ventures (JHTV) and a Pro bono Consultant in the Johns Hopkins Graduate Consulting Club (JHGCC).Hosted by Jenna Glatzer and Gustavo Carrizo.We are looking for PhD students from Hopkins, as well as other Institutions in and outside the US!If you are interested  in being interviewed for My PhD please complete the following form and we will get in touch with you:MyPhD podcast application form: https://docs.google.com/forms/d/e/1FAIpQLScNA8TVvuajm9PeNJT9J0KnOLhOWluCegECALe_XSEWFQBWSQ/viewform?usp=sf_link

The 7investing Podcast
7investing Explains: How are Medical Devices and Genetic Tests Regulated?

The 7investing Podcast

Play Episode Listen Later Oct 14, 2021 26:56


Given the rise of exciting new therapeutic modalities ranging from mRNA to gene editing, investors would be forgiven for overlooking opportunities in medical devices. They might be worth a closer look though. In this episode of the 7investing podcast, the team's health-care trio provide a high-level overview of the regulatory environment for medical devices, describe why and how genetic tests are regulated as medical devices, and provide three examples of companies in the space and how they fit within the regulatory landscape. Medical devices are regulated by the U.S. Food and Drug Administration (FDA) within three categories: Class I devices are the simplest and least likely to pose safety risks. Examples include bedpans or medical gauze. These require regulatory clearance. Class II devices are more complicated and require more data within their regulatory submissions to ensure the safety and effectiveness of the device. Examples include X-ray machines or knee braces. These require regulatory clearance. Class III devices are the most complicated and pose the greatest potential risk to patients, such as life-supporting, life-sustaining, or implantable devices. Examples include liquid biopsies, pacemakers, or implantable contact lenses. These require regulatory approval. Although Class I and Class II medical devices can be submitted through the 510(k) process and only need to show equivalence to a predicate ("existing") device, Class III medical devices must be submitted through the more rigorous premarket approval (PMA) process that often requires a clinical trial. Unlike a drug candidate that requires at least three separate clinical trials (phase 1, phase 2, and phase 3), a Class III medical device often only requires a single clinical trial. It seems odd, but genetic tests and liquid biopsies are also regulated as medical devices. These product candidates are categorized into one of the classes above, which typically impacts how and where they can be used. The three designations of genetic tests include: Research use only (RUO) products cannot be used as diagnostics and don't require a regulatory submission. RUOs can form the basis of a more advanced diagnostic product from the originator or its customers. These serve an important role, but generally have the smallest market opportunity. Laboratory developed tests (LDT) must be designed, manufactured, and processed by a single CLIA-certified laboratory. These tend to be Class II medical devices and require a 510(k) filing. LDTs are often used with centralized business models, where patient samples are shipped to a centralized facility. Examples include genetic screening tests. These have the largest volume potential, but low to moderate pricing and insurance coverage. These have moderate to large market opportunities. In vitro diagnostics (IVD) are more robust tests and can be shipped to the point of care, which means placed in the hands of doctors, oncologists, and medical facilities. Because these are not self-contained within CLIA-certified labs, they're often classified as Class III medical devices and require a PMA filing and clinical trial. IVDs are often used with distributed business models, where patient samples are processed at the point of care. Examples include liquid biopsies. These have both large volume and high price potential, which results in the largest market opportunities by monetary value. Finally, the podcast concludes with three different examples of medical device companies: 7investing Lead Advisor Dana Abramovitz discusses Inviate (NYSE: NVTA). 7investing Lead Advisor Maxx Chatsko discusses Nano-X Imaging (NASDAQ: NNOX). 7investing Lead Advisor Simon Erickson discusses STAAR Surgical (NASDAQ: STAA) --- Send in a voice message: https://anchor.fm/7investing/message Support this podcast: https://anchor.fm/7investing/support

Epigenetics Podcast
The Role of SMCHD1 in Development and Disease (Marnie Blewitt)

Epigenetics Podcast

Play Episode Listen Later Oct 14, 2021 30:46


In this episode of the Epigenetics Podcast, we caught up with Marnie Blewitt from the Walter and Eliza Hall Institute of Medical Research to talk about her work on the role of SMCHD1 in Development and Disease. The Laboratory of Marnie Blewitt focuses finding inhibitors or activators for the epigenetic regulator SMCHD1. Marnie Blewitt identified and characterized this protein during her PhD and the findings were published in 2008 in Nature Genetics. Since then, she and her team were able to investigate the function of this protein further. By doing so, they showed the involvement of SMCHD1 in cancer and several other diseases. Currently the lab is screening for small molecules that can act as inhibitors or activators of SMCHD1 the former as potential treatments for facioscapulohumeral muscular dystrophy, the latter for Prader Willi and Schaaf-Yang syndromes, both of which have no current targeted treatments.   References Blewitt, M. E., Gendrel, A.-V., Pang, Z., Sparrow, D. B., Whitelaw, N., Craig, J. M., Apedaile, A., Hilton, D. J., Dunwoodie, S. L., Brockdorff, N., Kay, G. F., & Whitelaw, E. (2008). SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation. Nature Genetics, 40(5), 663–669. https://doi.org/10.1038/ng.142 Leong, H. S., Chen, K., Hu, Y., Lee, S., Corbin, J., Pakusch, M., Murphy, J. M., Majewski, I. J., Smyth, G. K., Alexander, W. S., Hilton, D. J., & Blewitt, M. E. (2013). Epigenetic Regulator Smchd1 Functions as a Tumor Suppressor. Cancer Research, 73(5), 1591–1599. https://doi.org/10.1158/0008-5472.CAN-12-3019 Gordon, C. T., Xue, S., Yigit, G., Filali, H., Chen, K., Rosin, N., Yoshiura, K., Oufadem, M., Beck, T. J., McGowan, R., Magee, A. C., Altmüller, J., Dion, C., Thiele, H., Gurzau, A. D., Nürnberg, P., Meschede, D., Mühlbauer, W., Okamoto, N., … Reversade, B. (2017). De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal development. Nature Genetics, 49(2), 249–255. https://doi.org/10.1038/ng.3765   Related Episodes Epigenetics and X-Inactivation (Edith Heard) Biophysical Modeling of 3-D Genome Organization (Leonid Mirny) Unraveling Mechanisms of Chromosome Formation (Job Dekker)   Contact Active Motif on Twitter Epigenetics Podcast on Twitter Active Motif on LinkedIn Active Motif on Facebook Email: podcast@activemotif.com

Science in Parallel
Season One, Episode Five -- Alternative Energy

Science in Parallel

Play Episode Listen Later Oct 13, 2021 38:15


Avoiding the changing climate's most extreme impacts will require a technological revolution to power daily life from renewable sources. An entrepreneur, an engineering professor and a DOE-laboratory materials scientist – all DOE CSGF and Massachusetts Institute of Technology alumni – discuss technical challenges from nuclear energy to heat transfer to hydrogen generation and the importance of choosing high-impact research problems. In addition to talking about science, engineering and computation, they highlight the need for a strong social and political movement to drive a complete overhaul of our energy infrastructure. You'll meet: Leslie Dewan is a nuclear engineering entrepreneur and venture capitalist, who is currently the CEO of RadiantNano, a startup focused on radiation detection, identification and imaging. Asegun Henry is an MIT associate professor of mechanical engineering. What he calls his “sun in a box” design could lead to a viable system for storing renewable energy for the electrical grid. Brandon Wood is the associate program lead for Hydrogen and Computational Energy Materials at Lawrence Livermore National Laboratory and deputy director of the Laboratory for Energy Applications for the Future (LEAF).

Kyiv Future
E252 Anastasiia Bovkun: International Management Student @ Karazin University

Kyiv Future

Play Episode Listen Later Oct 12, 2021 44:05


Anastasiia Bovkun has taken parts in various projects such as «Go Camp» by organization GoGlobal, «Laboratory of Superheroes» by organization Ukrainian Leadership Academy, «Teenovation and Democracy HUB» by Klitschko Foundation, «ENGin» program, and «UPSHIFT Ukraine» where her team received financing for their project. Anastasiia also created many social projects such as WoWrecords, Live together, Academy of Superheroes, Happy paw. Currently, she was a student of Boston University for one month thanks to EducationUSA, and she is studying International Management and Communication in Business at V.N. Karazin Kharkiv National University. Born in Bilozerske in Donetsk Region, Anastasiia loves journalism as well as the English language. And she likes self-development, therefore she reads books, engages in sports, and focuses on her mental health. Instagram: @bovkkun

Voices from The Bench
185: "Avery"body Should Listen To David Avery

Voices from The Bench

Play Episode Listen Later Oct 11, 2021 67:53


Conversa à Bancada: a dental laboratory podcast out of Portugal (https://podcasts.apple.com/us/podcast/conversa-%C3%A0-bancada/id1564666913) Join Elvis and Barb at the Whip Mix Digital Forum October 29 & 30 in Louisville, Ky (https://www.whipmix.com/special-events/2021-digital-forum/) When you hear of people consulting in our industry, you would hope that they spent some time in our industry doing what they are "consulting". David Avery has done it all. Classically trained in school, worked in-house for a prosthodontist, owned his own lab, and help grow one of the largest labs on the east coast. David talks about the people who have influenced him along the way, how our profession has changes over the years, and what labs and technicians can do to prepare themselves for success in the coming years. Gro3X (https://www.gro3x.com/) is a dental supply, service and marketing company that was founded by Norbert Ulmer and their goal is to help dental labs, and especially small labs to lower their cost for supplies, provide business opportunities, and generate growth. Attend their upcoming Gro3X Gem Talks on November 5th in Charlotte, NC (https://www.gro3x.com/collections/family/products/gro3x-gem-talks). Gro3X Gem Talks is an all day marketing symposium in Ted-Talk style featuring some 10+ lab speakers as they share their most relevant and practical marketing techniques. We will hear from Sasha der Avanessian from Harvest Dental (https://harvestdental.com/), Anne Kelzer from AMK Dental Lab (https://www.facebook.com/people/AMK-Dental-Lab/100028120884702/), Frankie Acosta from AA Dental Design (https://www.aadentaldesign.com/) and Ricki Braswell from Beyond Coaching (https://www.transitionbeyond.com/) and former Co-Executive Director of the NADL. All of them will talk about real marketing as it is done in their own labs and businesses every day. Register now at gro3x.com to take advantage of their early bird special of only $95. Enter discount code VFTB for Voices from The Bench and receive an extra 10% discount, just because you listen to this Podcast. The Asiga MAX (https://whipmix.com/products/asiga-max/), the world's most advanced lab 3D printer, offers exceptional productivity. Well over 400 labs in the U.S. can attest to its accuracy, speed and precision. With 62 micron Print Precision, the Max is optimized for both dental lab or clinic environments. Its exclusive SPS™ Smart-Positioning-System Technology guarantees every layer is formed accurately, resulting in consistent results in any environment, and its single Point Calibration makes calibration extremely accurate and fast. As an Open Material System, you can print any suitable resin from any material manufacturer. Your choice, no strings. The Max also features the Fastest Material Changeover of any 3D printer. Labs LOVE this! Change completely from one print resin to another in under 30 seconds. All this and the finest, most dependable technical support staff in the dental lab industry. Call Whip Mix today or visit whipmix.com (https://whipmix.com/) to find out more about the Asiga Max! Have you seen the high prices of precious metal these days? They are close to record highs on gold and palladium. With those high precious metal prices, you are paying a high cost for your alloys. We know that you are using less Precious metal in your lab these days, but if you send in half of what you sent in 5 years ago ,your scrap return will be higher than it was 5 years ago ,because of the high PM prices . You owe it to yourself to find a trusted, reputable refining company. Look no further! Kulzer refining (https://www.kulzerus.com/en_us/en_us/heraeuspreciousmetalsrefining/scraprefining.aspx) has been tested, trusted and reputable for over 100 years. They burn, melt and assay all under one roof at their state-of-the-art refining facility in Wartburg Tennessee. They have doubled their production capacity to ensure your scrap return within 2 weeks. With all the non-precious material that has become present in today's restorations it is important that we ensure the assay sample is homogenous. At Kulzer (https://www.kulzerus.com/en_us/en_us/home_9/home.aspx), they take the extra step to X-ray the top and bottom after they melt the bar to make sure the precious metal percentages--- are the same. If not, copper is added until they are positive the bar is homogeneous. We know this step is very important to get a precise assay result. Their reimbursement to the customer is after our 10% refining fee. They have zero additional fees. If you need any free shipping containers, which contain a UPS prepaid, full insured label, please visit mydental360.com/refining or call the Director of Precious Metal Refining, Tony Circelli, directly at (914) 906-1843. Special Guest: David Avery AS, CDT, TE.

The Science Hour
Youngest rock samples from the moon

The Science Hour

Play Episode Listen Later Oct 10, 2021 63:56


n December 2020, China's Chang'e-5 mission returned to earth carrying rock samples collected from the moon – the first lunar samples to be collected since the American Apollo and Luna missions to the moon in the 1970s. Laboratory analysis has revealed that these are the youngest samples of rocks to be collected from the moon. Lunar geologist Katherine Joy explains what this tells us about the moon's volcanic past. Also on the programme, a recent study reveals that the hepatitis B virus has been infecting humans for at least 10,000 years. Denise Kühnert from the Max Planck Institute for the Science of Human History shares what the evolution of the virus tells us about human evolution, as well as the rise and fall of civilisations. In the wake of Cyclone Shaheen, we also speak to Princeton University's Ning Lin about how climate modelling can help us predict tropical storms in the Arabian Sea, and Fredi Otto joins us to discuss the 2021 Nobel Prizes for Science. Snails are a major enemy of gardeners around the world, invading vegetable patches and gobbling prize plants. CrowdScience listener Alexandre reckons he's removed thousands of them from his garden, which got him wondering: apart from eating his garden to the core, what's their wider role in nature? Would anyone or anything miss them if they suddenly disappeared? And for that matter, what about other creatures? We all know how complex biodiversity is, but it seems that some animals are more important than others in maintaining the balance of life on earth. Is there anything that could go extinct without having knock-on effects? CrowdScience heads to the Hawaiian mountains, a snail diversity hotspot, to discover the deep value of snails to native ecosystems there. Researchers and conservationists are working together to protect these highly endangered snails, and their natural habitats, from multiple threats. We hear why all snails – even the ones munching Alexandre's petunias – have their role to play in the natural world, and get to grips with cascading extinctions: how the loss of a single species can trigger unpredictable effects on a whole ecosystem. (Image: Getty Images)

Science in Action
Youngest rock samples from the moon

Science in Action

Play Episode Listen Later Oct 7, 2021 28:45


In December 2020, China's Chang'e-5 mission returned to earth carrying rock samples collected from the moon – the first lunar samples to be collected since the American Apollo and Luna missions to the moon in the 1970s. Laboratory analysis has revealed that these are the youngest samples of rocks to be collected from the moon. Lunar geologist Katherine Joy explains what this tells us about the moon's volcanic past. Also on the programme, a recent study reveals that the hepatitis B virus has been infecting humans for at least 10,000 years. Denise Kühnert from the Max Planck Institute for the Science of Human History shares what the evolution of the virus tells us about human evolution, as well as the rise and fall of civilisations. In the wake of Cyclone Shaheen, we also speak to Princeton University's Ning Lin about how climate modelling can help us predict tropical storms in the Arabian Sea, and Fredi Otto joins us to discuss the 2021 Nobel Prizes for Science. (Image: Getty Images) Presenter: Roland Pease Producer: Samara Linton

Late Fee Cinema
Voice Actor Candi Milo

Late Fee Cinema

Play Episode Listen Later Oct 6, 2021 67:58


Ryan and Carson speak with Voice Actor Candi Milo about her illustrious film/tv career, auditioning for Steven Spielberg, and working with LeBron James on Space Jam: A New Legacy. Candi has worked on projects such as My Life as a Teenage Robot, Dexter's Laboratory, Jimmy Neutron: Boy Genius, Looney Tunes, and more! 

Lab Culture
How two New Jersey lab scientists launched an unprecedented prenatal lead and mercury screening program

Lab Culture

Play Episode Listen Later Oct 5, 2021 72:19


Eric Bind and Andrew Steffens, scientists at the New Jersey Public Health and Environmental Laboratories, knew their lab was capable of screening expectant mothers and newborn babies for lead and mercury. But creating a program that also included important clinical interventions was unprecedented. On this episode of Lab Culture, they share how they pioneered this valuable program and established a precedent for others. Links: NJ Biomonitoring Website  Lead and Mercury Educational Materials (English) Prenatal Screening Mercury Questionnaire  NJDEP Fish Advisory  Boston Birth Cohort Study: Lead Paper Boston Birth Cohort Study: Mercury Paper CDC: Heavy Metals during Pregnancy CDC: Pregnancy Information Pediatric Environmental Health Specialty Units (PEHSUs) Lead and Mercury Educational Materials (Spanish) Lead and Mercury Educational Materials (French Creole) Lead and Mercury Educational Materials (Polish) Lead and Mercury Educational Materials (Portuguese) “New Jersey Laboratory Pioneers Prenatal Lead and Mercury Screening” (Lab Matters magazine)  

Voices from The Bench
184: Connecting Technicians and Labs with Andy Foster

Voices from The Bench

Play Episode Listen Later Oct 4, 2021 58:55


Every lab is looking for technicians. We all know about the lack of talent in the employee pool. What can we do about it? One man outside of London is attempting to help technicians and labs "hook up". Andy Foster comes on the podcast to talk about running his one person lab while at the same time running his website recruit4technicians.com (https://recruit4technicians.com/). This site is dedicated to our industry. If you are a technician looking for a career or are a lab looking for your next employee, this is an ideal place to post. Andy also talks about some interesting things he has noticed in our industry, some great ideas for labs when looking, and also some great ideas for technicians when looking for their next "home away from home". Great stuff for everyone in our industry. Check out Andy's Blog for more great resources for both the lab and the technicians. (https://recruit4technicians.com/blog/) Whip Mix (https://whipmix.com/) is pleased to add VeriCast OS (https://whipmix.com/products/vericast-generative-resin/), a burnout pattern print resin, to Whip Mix's growing Veri Brand Resin offering. VeriCast OS works with LCD and DLP printers in both 385 and 405 nanometer wavelengths. It prints accurate and detailed crowns, bridges, substructures, and RPD frameworks, is durable, and leaves no ash or residue. Since it burns out cleanly, VeriCast OS is ideal for investment casting and ceramic pressing. For optimal results, we recommend Whip Mix ResinVest (https://whipmix.com/products/resinvest-investment/), which is a phosphate investment made specifically for burning out printed or milled resin patterns. Visit whipmix.com to learn more about VeriCast OS or any of Whip Mix's other 3D Print Resins. Gro3X (https://www.gro3x.com/) is a dental supply, service and marketing company that was founded by Norbert Ulmer and their goal is to help dental labs, and especially small labs to lower their cost for supplies, provide business opportunities, and generate growth. Attend their upcoming Gro3X Gem Talks on November 5th in Charlotte, NC (https://www.gro3x.com/collections/family/products/gro3x-gem-talks). Gro3X Gem Talks is an all day marketing symposium in Ted-Talk style featuring some 10+ lab speakers as they share their most relevant and practical marketing techniques. We will hear from Sasha der Avanessian from Harvest Dental (https://harvestdental.com/), Anne Kelzer from AMK Dental Lab (https://www.facebook.com/people/AMK-Dental-Lab/100028120884702/), Frankie Acosta from AA Dental Design (https://www.aadentaldesign.com/) and Ricki Braswell from Beyond Coaching (https://www.transitionbeyond.com/) and former Co-Executive Director of the NADL. All of them will talk about real marketing as it is done in their own labs and businesses every day. Register now at gro3x.com to take advantage of their early bird special of only $95. Enter discount code VFTB for Voices from The Bench and receive an extra 10% discount, just because you listen to this Podcast. Have you seen the high prices of precious metal these days? They are close to record highs on gold and palladium. With those high precious metal prices, you are paying a high cost for your alloys. We know that you are using less Precious metal in your lab these days, but if you send in half of what you sent in 5 years ago ,your scrap return will be higher than it was 5 years ago ,because of the high PM prices . You owe it to yourself to find a trusted, reputable refining company. Look no further! Kulzer refining (https://www.kulzerus.com/en_us/en_us/heraeuspreciousmetalsrefining/scraprefining.aspx) has been tested, trusted and reputable for over 100 years. They burn, melt and assay all under one roof at their state-of-the-art refining facility in Wartburg Tennessee. They have doubled their production capacity to ensure your scrap return within 2 weeks. With all the non-precious material that has become present in today's restorations it is important that we ensure the assay sample is homogenous. At Kulzer (https://www.kulzerus.com/en_us/en_us/home_9/home.aspx), they take the extra step to X-ray the top and bottom after they melt the bar to make sure the precious metal percentages--- are the same. If not, copper is added until they are positive the bar is homogeneous. We know this step is very important to get a precise assay result. Their reimbursement to the customer is after our 10% refining fee. They have zero additional fees. If you need any free shipping containers, which contain a UPS prepaid, full insured label, please visit mydental360.com/refining or call the Director of Precious Metal Refining, Tony Circelli, directly at (914) 906-1843. Special Guest: Andy Foster.

Social Sport
#79 - Risa Isard on the limits of Title IX and an intersectional approach to equity in sports

Social Sport

Play Episode Listen Later Oct 4, 2021 53:09


Risa Isard is a sports industry veteran and policy expert. She specializes in advancing equity with and for girls and women, LGBTQ+ people, people of color, and others in and through sport. Her career in the sports industry spans professional and college sports, sports policy, and nonprofit thought leadership. She has developed partnerships with professional ninja athletes, hosted Billie Jean King in an on-stage conversation, directed the premier national event for increasing access to youth sports, co-authored and edited foundational research reports, established community-based partnerships to support sport leaders across the country, launched a first-of-its-kind online portal for community leaders, founded a farmer's market at professional baseball games, run a baseball league for people with special needs, hosted a celebrity soccer challenge, authored fortune cookies, and more. She is the former associate director of thought leadership for national nonprofit KABOOM!, former project director for the Aspen Institute Sports & Society Program, and former community relations coordinator for a minor league baseball team. She's also been on staff at Brandi Chastain's nonprofit organization, Duke University women's basketball, and the Phoenix Mercury. Risa has presented at South by Southwest (SXSW), Spotlight: Health at the Aspen Ideas Festival, the Surgeon General's Innovation Summit, the University of Pennsylvania's Law School Sports Symposium, the North American Society for Sport Management, and elsewhere. She has written for Sports Business Journal, AdWeek, Global Sport Matters, Quartz, espnW and elsewhere. Risa graduated cum laude from Duke with a specialized degree in “Social Change at the Intersection of Culture, Gender, and Sports,” simultaneously receiving honors for her original research thesis on the pre-history and early years of Title IX (1969-1975). A long-time advocate of using sports for social change, Risa is a Research Fellow in the Laboratory for Inclusion and Diversity in Sport at UMass, where she is currently pursuing a Ph.D. in Sport Management from the Isenberg School of Management. Quotes: --“This is definitely not sport-specific. Racial bias has long been documented in men's sports. There is less documentation, but no less convincing evidence, that it happens in women's sports as well. It can manifests in a number of different ways. It can be about the attention athletes get, it can be about the kind of attention they get, and it can be about the language we use when we talk about athletes...Absolutely, racial bias is pervasive in and across sports, and in women's sports." --“Title IX has fixed things unequally when it comes to girls. Title IX has been excellent for white, middle-upper class girls like me. It has been a lot less effective at creating equity for Black girls, Latinx girls, girls of color broadly, and girls from low income communities. The gender gaps that exist in some communities are still quite pervasive…Title IX, at its best, ought to create a more equitable society for all girls, and it hasn't done that yet.” Follow Risa on Twitter: @RisaLovesSports Follow Social Sport: Website, Instagram, Facebook, Twitter, Newsletter --- Support this podcast: https://anchor.fm/socialsport/support

20 Minute Leaders
Ep589: Noa Asher | CEO, NTT Innovation Laboratory Israel

20 Minute Leaders

Play Episode Listen Later Oct 4, 2021 22:55


Noa Asher was appointed as CEO of NTT Innovation Laboratory Israel on July first. NTT Israel serves as the focal point for NTT Group companies in Israel and their mission is to bring value to NTT by collaborating with Israeli companies and academia in various fields. NTT is one of the major players in the Japanese communication market and is considered a Fortune 100 company, with over $ 100 billion annual sales, more than 300,000 employees worldwide, operating in 80+ countries.From 2014-2020 Noa served as the Economic Minister at the Israeli Embassy in Tokyo where she was in charge of promoting trade and investments between Israel and Japan, supporting the revolution that happened during this time in the business relations between Israel and Japan. Noa joined the ministry of Economy in 2002 and held several positions at the foreign trade administration and the innovation authority including the commercial attaché in Chicago. Previously she was a legal advisor in a group of start-up companies.

AAOMPT Podcast
Ep. 77 Karanasios Interview

AAOMPT Podcast

Play Episode Listen Later Sep 30, 2021 34:35


Stefanos Karanasios (e-mail, ResearchGate, Google Scholar, Twitter) of the University of West Attica (Greece) and the Laboratory of Advanced Physiotherapy (L.Ad.Phys.) is interviewed by Dhinu Jayaseelan regarding a publication from the Journal of Hand Therapy titled, “Diagnostic accuracy of examination tests for lateral elbow tendinopathy (LET) – A systematic review.” This episode contains information that will be interesting for practitioners who want to understand what the scientific literature states about the controversial and ever evolving territory of examination maneuvers for lateral elbow tendinopathy.Find out more about the American Academy of Orthopaedic Manual Physical Therapists at the following links:Academy website: www.aaompt.orgTwitter: @AAOMPTFacebook: https://www.facebook.com/aaompt/Instagram: https://www.instagram.com/officialaaompt/?hl=enPodcast e-mail: aaomptpodcast@gmail.comPodcast website: https://aaomptpodcast.simplecast.fm

Polite Disagreements Podcast
Our Favorite Cartoon Shows

Polite Disagreements Podcast

Play Episode Listen Later Sep 30, 2021 95:33


Former Nickelodeon addicts, eat your hearts out! We revisit the cartoons we enjoyed most as kids (and a few we enjoy as adults) and wonder how the hell people came up with some of these things. Like CatDog...seriously, who thought that was a good idea? Join us in Dexter's Laboratory as we talk about our favorite toons.This month we are supporting National Suicide Prevention Lifeline in their effort to raise awareness of suicide prevention and save lives. Donate now to help support!https://suicidepreventionlifeline.org/donate/(Episode contains explicit material)Beach NeedZ Get all of the things you need for the beach through Beach NeedZ! Everything is Organic & Reef Safe!

Epigenetics Podcast
Single-Molecule Imaging of the Epigenome (Efrat Shema)

Epigenetics Podcast

Play Episode Listen Later Sep 30, 2021 39:47


In this episode of the Epigenetics Podcast, we caught up with Efrat Shema from the Weizmann Institute of Science to talk about her work on Single Molecule Imaging of chromatin, and the analysis of nucleosomes circulating in plasma. In ChIP-Seq experiments the peak you get as a read out represents an average over, most often, millions of cells. Furthermore, one often does not know if that peak represents one or more than one nucleosome. If you then want to study multiple marks at the same time, the question remains: do those modifications occur at the same time, in the same cell? The Laboratory of Efrat Shema works on answering those questions by developing methods to study the modification patterns on single nucleosomes with single molecule imaging. With that it is possible to study single nucleosomes in a high throughout manner to identify the modifications they are decorated with. A subsequent sequencing step makes it possible to identify the genomic location of that nucleosome.   References Shema, E., Bernstein, B. E., & Buenrostro, J. D. (2019). Single-cell and single-molecule epigenomics to uncover genome regulation at unprecedented resolution. Nature Genetics, 51(1), 19–25. https://doi.org/10.1038/s41588-018-0290-x Shema, E., Jones, D., Shoresh, N., Donohue, L., Ram, O., & Bernstein, B. E. (2016). Single-molecule decoding of combinatorially modified nucleosomes. Science, 352(6286), 717–721. https://doi.org/10.1126/science.aad7701 Shema, E., Kim, J., Roeder, R. G., & Oren, M. (2011). RNF20 Inhibits TFIIS-Facilitated Transcriptional Elongation to Suppress Pro-oncogenic Gene Expression. Molecular Cell, 42(4), 477–488. https://doi.org/10.1016/j.molcel.2011.03.011 Shema, E., Tirosh, I., Aylon, Y., Huang, J., Ye, C., Moskovits, N., Raver-Shapira, N., Minsky, N., Pirngruber, J., Tarcic, G., Hublarova, P., Moyal, L., Gana-Weisz, M., Shiloh, Y., Yarden, Y., Johnsen, S. A., Vojtesek, B., Berger, S. L., & Oren, M. (2008). The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression. Genes & Development, 22(19), 2664–2676. https://doi.org/10.1101/gad.1703008   Related Episodes ATAC-Seq, scATAC-Seq and Chromatin Dynamics in Single-Cells (Jason Buenrostro) Investigating the Dynamics of Epigenetic Plasticity in Cancer with Single Cell Technologies (Céline Vallot) The Past, Present, and Future of Epigenetics (Joe Fernandez, founder of Active Motif)   Contact Active Motif on Twitter Epigenetics Podcast on Twitter Active Motif on LinkedIn Active Motif on Facebook Email: podcast@activemotif.com

The Pakistan Experience
Is Pakistan safe for Journalism? - Raza Rumi - New Media and Naya Daur - TPE # 131

The Pakistan Experience

Play Episode Listen Later Sep 28, 2021 92:05


Raza Rumi joins us on this deep dive podcast to discuss why he had to leave Pakistan, the shrinking space for Journalism in the country, how digital journalism is changing the landscape, the philosophy behind Naya Daur, new media and nation building. What do we need to do to build a Pakistani state? Should journalists be scared of the new laws? What is the role of journalism? Find out this, and more on this week's episode of The Pakistan Experience. The Pakistan Experience is an independently run podcast. Please consider supporting us on Patreon: https://www.patreon.com/thepakistanexperience And Please stay in touch: https://twitter.com/ThePakistanExp1 https://www.facebook.com/thepakistanexperience https://instagram.com/thepakistanexpeperience The podcast is hosted by comedian and writer, Shehzad Ghias Shaikh. Shehzad is a Fulbright scholar with a Masters in Theatre from Brooklyn College. He is also one of the foremost Stand-up comedians in Pakistan and frequently writes for numerous publications. He can be found on Facebook, Instagram, Twitter and Tinder. https://www.facebook.com/Shehzadghias/ https://twitter.com/shehzad89 Raza Ahmad Rumi is a Pakistani writer and a public policy specialist currently based in Ithaca, USA. He is the Director, Park Center for Independent Media, Ithaca College and has been teaching in Journalism department since 2015. He is also visiting faculty at Cornell Institute for Public Affairs and teaches courses in international development and public policy. Earlier, Raza was a global faculty fellow at the Gallatin School, New York University (Spring 2016). Raza was a fellow at New America Foundation (2014); United States Institute of Peace (Sept 2014-March 2015), a fellow at National Endowment for Democracy (summer 2016); and currently a member of Think Tank at Laboratory for Global Performance and Politics, Georgetown University. He is also a senior fellow at the Jinnah Institute in Islamabad. In recent years, Raza founded a digital media platform NayaDaur Media in collaboration with Pakistani diaspora in the United States. It is a bilingual multimedia portal with a Youtube channel. From 2017-2019, Raza was also the editor of Pakistan's national newspaper Daily Times. From 2005-2017, he was affiliated with weekly The Friday Times in various editorial positions. Raza was also a commentator and a current affairs talk show host in Pakistan and was affiliated with the Express TV, Pakistan before he left Pakistan in 2014. He contributes regularly to Foreign Policy, Huffington Post, New York Times, The Diplomat, Fair Observer, CNN and Al Jazeera, Daily O, Scroll India, The Hindu and Indian Express. His columns for the Express Tribune can be accessed here. Prior to his foray in journalism, Raza worked as a governance and capacity development specialist for the Asian Development Bank, the Government of Pakistan, a number of Pakistani nongovernmental organizations, and the United Nations Mission in Kosovo. He has also been an academic adviser to the Network of Asia Pacific Schools and Institutes of Public Administration and Governance (NAPSIPAG); a public policy adviser to LEAD Pakistan, a nonprofit focused on sustainable development; and was an advisory board member of both the ASR Resource Centre and the South Asian Institute of Women's Studies in Lahore. As a freelance policy professional/consultant he continues to advise international development organizations, governments and NGOs. Books: He is also the author of Delhi by Heart: Impressions of a Pakistani Traveler (Harper Collins, 2013); The Fractious Path: Pakistan's Democratic Transition (2016); Identity, Faith and Conflict: Essays on Pakistan & Beyond (2017); and Being Pakistani–Essays on Arts, Culture & Society (2018).

PFAS Pulse Podcast
September 28, 2021 - EPA's First Validated Laboratory Method, EPA's Preliminary Effluent Guidelines Program Plan

PFAS Pulse Podcast

Play Episode Listen Later Sep 28, 2021 16:14


On the PFAS Pulse Podcast Episode 1, Tom and Shaun discuss the EPA's announcement of the first validated laboratory testing method, what that means, and how it changes the future of PFAS. The guys then also touch upon the EPA's Preliminary Effluent Guidelines Program Plan, and dive into what that means. To close out the episode Shaun goes over some PFAS news at the local level.As always, to get the latest and greatest, make sure you're subscribed to the Pulse! hrpassociates.com/pfas

Earth Wise
Harnessing The Smell Of Fear | Earth Wise

Earth Wise

Play Episode Listen Later Sep 28, 2021 2:00


Plant-eating insects present a major problem for farmers and home gardeners.  Aphids, for example, are a highly destructive pest to many crops.  Their large numbers and ability to transmit plant pathogens make them a persistent problem for growers. Pesticides are chemical substances that are commonly used to prevent, destroy, repel or mitigate pests.  They include […]

Voices from The Bench
183: The Emerick's Go To The Forum: Michael, Austin & Alex Emerick with Bernie Jaroslow

Voices from The Bench

Play Episode Listen Later Sep 27, 2021 61:04


After a year of many dental meetings being canceled, Whip Mix (https://www.whipmix.com/) has come back bigger and better with the Digital Forum (https://www.whipmix.com/special-events/2021-digital-forum/). This year in Louisville, Ky October 29 & 30, is sure to be the best forum yet. Bernie Jaroslow comes on the podcast to talk about all the amazing speakers they have lined up along with some fun evening events that you will not want to miss. Also joining the episode is a father and two sons that have been to ALL 9 digital forums. Michael Emerick opened Emerick Crown and Bridge Lab (https://emerickdentallab.com/) in Cincinnati, Oh. After raising two sons in the lab, Austin and Alex are now full integrated in the digital workflow bringing a new and welcome passion to their family business. Gro3X (https://www.gro3x.com/) is a dental supply, service and marketing company that was founded by Norbert Ulmer and their goal is to help dental labs, and especially small labs to lower their cost for supplies, provide business opportunities, and generate growth. Attend their upcoming Gro3X Gem Talks on November 5th in Charlotte, NC (https://www.gro3x.com/collections/family/products/gro3x-gem-talks). Gro3X Gem Talks is an all day marketing symposium in Ted-Talk style featuring some 10+ lab speakers as they share their most relevant and practical marketing techniques. We will hear from Sasha der Avanessian from Harvest Dental (https://harvestdental.com/), Anne Kelzer from AMK Dental Lab (https://www.facebook.com/people/AMK-Dental-Lab/100028120884702/), Frankie Acosta from AA Dental Design (https://www.aadentaldesign.com/) and Ricki Braswell from Beyond Coaching (https://www.transitionbeyond.com/) and former Co-Executive Director of the NADL. All of them will talk about real marketing as it is done in their own labs and businesses every day. Register now at gro3x.com to take advantage of their early bird special of only $95. Enter discount code VFTB for Voices from The Bench and receive an extra 10% discount, just because you listen to this Podcast. Using 3D printed Dentca Temporary Resin is the easy, fast, clean and accurate way of creating natural-looking temporary restorations using Dentca Temporary C&B 3D Print Resin (https://whipmix.com/products/dentca-temporary-crown-bridge-resin/) from Whip Mix (https://whipmix.com/). The new temporary material is FDA cleared, biocompatible, photocurable, and can be printed fast. That patient can be temporized with the highest quality temporary crowns that last a minimum of one full year in the mouth. Dentca C&B Temporary features excellent life-like esthetics and shade-matching capability with Vita shades A1, A2, A3, A3.5, B1, B2, and BL (Bleach). Dentca Temporary C&B resin is validated for use with the Asiga Max (https://whipmix.com/products/asiga-max/), Asiga Pro 2, Asiga Pro 4K (https://whipmix.com/products/asiga-pro-4k/), and the Whip Mix Veribuild printers (https://whipmix.com/products/veribuild-lcd/), and with the following curing units: Uvitron (SunRay 400 (https://whipmix.com/products/uvitron-uv-sunray-400-curing-unit/) and IntelliRay 600 (https://whipmix.com/products/uvitron-uv-curing-unit/)), and the CUREbox Plus (https://whipmix.com/products/curebox-plus/). For more information, visit www.whipmix.com. Special Guests: Alex Emerick, Austin Emerick, Bernie Jaroslow CDT, and Michael Emerick.

New Books in History
Chris Bleakley, "Poems That Solve Puzzles: The History and Science of Algorithms" (Oxford UP, 2020)

New Books in History

Play Episode Listen Later Sep 27, 2021 81:13


As algorithms become ever more significant to and embedded in our everyday lives, ever more accessible introductions to them are needed. While several excellent technical and critical treatments have emerged in recent years, i had not come across a book for the general public that would provide a deep sense for the intuitions and motivations behind their development. Chris Bleakley's new book offers this and more: conceptual rigor woven into historical vignettes in a style that i believe general readers will find truly enjoyable to read. Poems that Solve Puzzles: The History and Science of Algorithms (Oxford UP, 2020) is itself a quite poetic book, in which echoes of ideas and variations on themes can be heard throughout. Its stories encompass the early hypothetical and mechanical computers, the charactered rise of weather forecasting, the origins (and lulls) of machine learning, and the sensational competitions between master game players and artificial intelligence. The book traverses a long historical arc, but each episode is a quick read, remarkable in their ability to convey depth and rigor in crisp, plain language. It was a delight to talk with Chris about these and other aspects of his book. Suggested companion works: --Simon Singh, The Code Book --George Dyson, Turing's Cathedral: The Origins of the Digital Universe --Greg Kohs (director), "AlphaGo" Chris Bleakley is Head of the School of Computer Science at University College Dublin. He graduated with a BSc (Hons) degree in Computer Science from Queen's University, Belfast, and a PhD degree in Electronic Engineering from Dublin City University. After college, he was employed as a software consultant by Accenture and, later, as a senior telecommunications researcher at Broadcom Eireann Research. Cory Brunson is an Assistant Professor at the Laboratory for Systems Medicine at the University of Florida. His research focuses on geometric and topological approaches to the analysis of medical and healthcare data. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/history

New Books in Intellectual History
Chris Bleakley, "Poems That Solve Puzzles: The History and Science of Algorithms" (Oxford UP, 2020)

New Books in Intellectual History

Play Episode Listen Later Sep 27, 2021 81:13


As algorithms become ever more significant to and embedded in our everyday lives, ever more accessible introductions to them are needed. While several excellent technical and critical treatments have emerged in recent years, i had not come across a book for the general public that would provide a deep sense for the intuitions and motivations behind their development. Chris Bleakley's new book offers this and more: conceptual rigor woven into historical vignettes in a style that i believe general readers will find truly enjoyable to read. Poems that Solve Puzzles: The History and Science of Algorithms (Oxford UP, 2020) is itself a quite poetic book, in which echoes of ideas and variations on themes can be heard throughout. Its stories encompass the early hypothetical and mechanical computers, the charactered rise of weather forecasting, the origins (and lulls) of machine learning, and the sensational competitions between master game players and artificial intelligence. The book traverses a long historical arc, but each episode is a quick read, remarkable in their ability to convey depth and rigor in crisp, plain language. It was a delight to talk with Chris about these and other aspects of his book. Suggested companion works: --Simon Singh, The Code Book --George Dyson, Turing's Cathedral: The Origins of the Digital Universe --Greg Kohs (director), "AlphaGo" Chris Bleakley is Head of the School of Computer Science at University College Dublin. He graduated with a BSc (Hons) degree in Computer Science from Queen's University, Belfast, and a PhD degree in Electronic Engineering from Dublin City University. After college, he was employed as a software consultant by Accenture and, later, as a senior telecommunications researcher at Broadcom Eireann Research. Cory Brunson is an Assistant Professor at the Laboratory for Systems Medicine at the University of Florida. His research focuses on geometric and topological approaches to the analysis of medical and healthcare data. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/intellectual-history

Nerd Rage! The Great Debates
It's a Mad (Scientist) World

Nerd Rage! The Great Debates

Play Episode Listen Later Sep 27, 2021 37:11


Get them bunsen beakers burning and cue up the lightning in the background, as on this episode, we're talking our favorite mad scientists in all of fiction! From Dr. Strangelove to Dexter from "Dexter's Laboratory," and Dr. Light from the Megaman games to... Dr. Pepper. Yeah, that one. Whether you're blinded by science or personal insults, always be ready to RAGE!And check out this game, as mentioned by Chandru!Hosted By: Marc AbrigoSpecial Guests: Dane Fox McGraw, Kristee Ono, Stephen Ku, Tittymari Jothi, and Chandru VittalProduced by Komedio ComedyFind more episodes of Nerd Rage! The Great Debates at NerdRagePodcast.comTo stay informed on Komedio live shows and podcasts visit http://Komed.io✉️ e-Mail us at KomedioComedy@gmail.com (put “Nerd Rage” in the subject line)Find us on Twitter at https://twitter.com/nerdragetgd or follow us on Facebook at https://www.facebook.com/nerdrageTGD for more updates.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

New Books Network
Chris Bleakley, "Poems That Solve Puzzles: The History and Science of Algorithms" (Oxford UP, 2020)

New Books Network

Play Episode Listen Later Sep 27, 2021 81:13


As algorithms become ever more significant to and embedded in our everyday lives, ever more accessible introductions to them are needed. While several excellent technical and critical treatments have emerged in recent years, i had not come across a book for the general public that would provide a deep sense for the intuitions and motivations behind their development. Chris Bleakley's new book offers this and more: conceptual rigor woven into historical vignettes in a style that i believe general readers will find truly enjoyable to read. Poems that Solve Puzzles: The History and Science of Algorithms (Oxford UP, 2020) is itself a quite poetic book, in which echoes of ideas and variations on themes can be heard throughout. Its stories encompass the early hypothetical and mechanical computers, the charactered rise of weather forecasting, the origins (and lulls) of machine learning, and the sensational competitions between master game players and artificial intelligence. The book traverses a long historical arc, but each episode is a quick read, remarkable in their ability to convey depth and rigor in crisp, plain language. It was a delight to talk with Chris about these and other aspects of his book. Suggested companion works: --Simon Singh, The Code Book --George Dyson, Turing's Cathedral: The Origins of the Digital Universe --Greg Kohs (director), "AlphaGo" Chris Bleakley is Head of the School of Computer Science at University College Dublin. He graduated with a BSc (Hons) degree in Computer Science from Queen's University, Belfast, and a PhD degree in Electronic Engineering from Dublin City University. After college, he was employed as a software consultant by Accenture and, later, as a senior telecommunications researcher at Broadcom Eireann Research. Cory Brunson is an Assistant Professor at the Laboratory for Systems Medicine at the University of Florida. His research focuses on geometric and topological approaches to the analysis of medical and healthcare data. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

Simblified
Solving Genetic Diseases Ft. Berty Ashley

Simblified

Play Episode Listen Later Sep 27, 2021 74:18


One of the smartest people we know joins us on the show! Berty Ashley is a good friend and a quizzer, music nerd and... Molecular biologist who by day works with a private organization called DART, helping to solve rare diseases, putting all us PPT-makers in our place! Jokes apart, the work Berty and his team does is fascinating and this is a conversation we've been thinking of having for months now. He is also inspirational and hilarious, leading to a fun conversation. Also touching upon the meaningfulness of the work that he does and lots more.You can say hello to Berty at

Podcasts from the Cochrane Library
Are laboratory-made, COVID-19-specific monoclonal antibodies an effective treatment for COVID-19?

Podcasts from the Cochrane Library

Play Episode Listen Later Sep 22, 2021 4:49


Cochrane is producing a series of reviews to help decision makers respond to the COVID-19 pandemic. In September 2021, we published the first version of a Living Systematic Review on the effects of monoclonal antibodies for treating COVID-19 and in this podcast we speak to Nina Kreuzberger one of the lead authors, about the review, which was initiated in the Germany-wide joint projects "COVIM" and "CEOsys" and funded by the Federal Ministry of Education and Research of Germany.

Podcasts from the Cochrane Library
Are laboratory-made, COVID-19-specific monoclonal antibodies an effective treatment for COVID-19?

Podcasts from the Cochrane Library

Play Episode Listen Later Sep 22, 2021 4:49


Cochrane is producing a series of reviews to help decision makers respond to the COVID-19 pandemic. In September 2021, we published the first version of a Living Systematic Review on the effects of monoclonal antibodies for treating COVID-19 and in this podcast we speak to Nina Kreuzberger one of the lead authors, about the review, which was initiated in the Germany-wide joint projects "COVIM" and "CEOsys" and funded by the Federal Ministry of Education and Research of Germany.

Learning Bayesian Statistics
#47 Bayes in Physics & Astrophysics, with JJ Ruby

Learning Bayesian Statistics

Play Episode Listen Later Sep 21, 2021 75:47


The field of physics has brought tremendous advances to modern Bayesian statistics, especially inspiring the current algorithms enabling all of us to enjoy the Bayesian power on our own laptops. I did receive some physicians already on the show, like Michael Betancourt in episode 6, but in my legendary ungratefulness I hadn't dedicated a whole episode to talk about physics yet. Well that's now taken care of, thanks to JJ Ruby. Apart from having really good tastes (he's indeed a fan of this very podcast), JJ is currently a postdoctoral fellow for the Center for Matter at Atomic Pressures at the University of Rochester, and will soon be starting as a Postdoctoral Scholar at Lawrence Livermore National Laboratory, a U.S. Department of Energy National Laboratory. JJ did his undergraduate work in Astrophysics and Planetary Science at Villanova University, outside of Philadelphia, and completed his master's degree and PhD in Physics at the University of Rochester, in New York. JJ studies high energy density physics and focuses on using Bayesian techniques to extract information from large scale physics experiments with highly integrated measurements. In his freetime, he enjoys playing sports including baseball, basketball, and golf. Our theme music is « Good Bayesian », by Baba Brinkman (feat MC Lars and Mega Ran). Check out his awesome work at https://bababrinkman.com/ (https://bababrinkman.com/) ! Thank you to my Patrons for making this episode possible! Yusuke Saito, Avi Bryant, Ero Carrera, Brian Huey, Giuliano Cruz, Tim Gasser, James Wade, Tradd Salvo, Adam Bartonicek, William Benton, Alan O'Donnell, Mark Ormsby, Demetri Pananos, James Ahloy, Jon Berezowski, Robin Taylor, Thomas Wiecki, Chad Scherrer, Nathaniel Neitzke, Zwelithini Tunyiswa, Elea McDonnell Feit, Bertrand Wilden, James Thompson, Stephen Oates, Gian Luca Di Tanna, Jack Wells, Matthew Maldonado, Ian Costley, Ally Salim, Larry Gill, Joshua Duncan, Ian Moran, Paul Oreto, Colin Caprani, George Ho, Colin Carroll, Nathaniel Burbank, Michael Osthege, Rémi Louf, Clive Edelsten, Henri Wallen, Hugo Botha, Vinh Nguyen, Raul Maldonado, Marcin Elantkowski, Tim Radtke, Adam C. Smith, Will Kurt, Andrew Moskowitz, Hector Munoz, Marco Gorelli, Simon Kessell, Bradley Rode, Patrick Kelley, Rick Anderson, Casper de Bruin, Philippe Labonde, Matthew McAnear, Michael Hankin and Cameron Smith. Visit https://www.patreon.com/learnbayesstats (https://www.patreon.com/learnbayesstats) to unlock exclusive Bayesian swag ;) Links from the show: Center for Matter at Atomic Pressures: https://www.rochester.edu/cmap/ (https://www.rochester.edu/cmap/) Laboratory for Laser Energetics: https://www.lle.rochester.edu/index.php/about-the-laboratory-for-laser-energetics/ (https://www.lle.rochester.edu/index.php/about-the-laboratory-for-laser-energetics/) Lawrence Livermore National Laboratory: https://www.llnl.gov/ (https://www.llnl.gov/) JJ's thesis -- Bayesian Inference of Fundamental Physics at Extreme Conditions: https://www.lle.rochester.edu/media/publications/documents/theses/Ruby.pdf (https://www.lle.rochester.edu/media/publications/documents/theses/Ruby.pdf) Recent Fusion Breakthrough: https://www.llnl.gov/news/national-ignition-facility-experiment-puts-researchers-threshold-fusion-ignition (https://www.llnl.gov/news/national-ignition-facility-experiment-puts-researchers-threshold-fusion-ignition) LBS #6, A principled Bayesian workflow, with Michael Betancourt: https://www.learnbayesstats.com/episode/6-a-principled-bayesian-workflow-with-michael-betancourt (https://www.learnbayesstats.com/episode/6-a-principled-bayesian-workflow-with-michael-betancourt) 20 Best Statistics Podcasts of 2021: https://welpmagazine.com/20-best-statistics-podcasts-of-2021/ (https://welpmagazine.com/20-best-statistics-podcasts-of-2021/) E.T. Jaynes, Probability Theory -- The Logic of Science: https://www.goodreads.com/book/show/151848.Probability_Theory... Support this podcast

Lab Out Loud
A Greater Call to Connect with Scientists

Lab Out Loud

Play Episode Listen Later Sep 20, 2021 36:58


As schools transitioned to online learning in 2020 during the COVID-19 pandemic, Skype a Scientist saw a increased demand for their service. Boasting a database of thousands of scientists, SKYPE a Scientist uses readily available video chat tools to connect scientists to teachers, students and other groups around the world. Founder and Executive Director Sarah McAnulty joins the Lab Out Loud podcast to talk about Skype a Scientist and its increased programming, how the resource grew during the pandemic, and it fills a growing need to connect students and teachers with scientific experts. About The Guest Sarah McAnulty is an American squid biologist who earned her bachelor's degree in marine science at Boston University in 2011 and got her PhD from the department of Molecular and Cell Biology at the University of Connecticut, graduating in 2019. She is the founder and executive director of Skype a Scientist, a non-profit organization that connects scientists and teachers around the world. Show notes at: https://laboutloud.com/2021/09/episode-251-skype-a-scientist/

Voices from The Bench
182: Collaboration, Communication, and Caring with Eric Kukucka DD

Voices from The Bench

Play Episode Listen Later Sep 20, 2021 65:21


When you think of world-famous Denturist, who comes to mind? Because of the lack of legal states in America, the list is short. But there is one gentleman out of Windsor, Canada who has been promoting the profession for years online. Eric Kukucka, from the Denture Center (https://thedenturecenter.ca/), comes on the podcast to talk about finding out that he wanted to be a denturist at a young age, getting in to school, partnering with Ivoclar (https://www.ivoclarvivadent.com/en_US) and 3shape (https://www.3shape.com/en-us), opening a few practices, and helping develop the complete digital workflow when it comes to removables. Whip Mix (https://www.whipmix.com/)'s new Veriwash (https://www.whipmix.com/products/veriwash/) resin cleaning station is the ideal piece of equipment to use in the 3D printed resin post process. It's oscillating, multi-speed stirrer produces a tornado-like vortex every 30-seconds, and guarantees efficient, effective and powerful cleaning whether the units are individual or still attached to the build plate. The two alcohol baths make an effective step-wash system. It cleans more efficiently and there is less alcohol needed, since it is re-used for both a fresh bath and a dirty bath. The VeriWash's intelligent design offers features such as Mode, Time, and Start/Stop button display which gives the operator full and automatic control of the cleaning process. A mesh basket used in the wash container makes it easy to keep track of small printed parts when cleaning. The affordable unit's one-year warranty ensures peace-of-mind for the owner. Visit whipmix.com (https://www.whipmix.com/) or call (800) 626-5651 for more information about this great new product. Gro3X (https://www.gro3x.com/) is a dental supply, service and marketing company that was founded by Norbert Ulmer and their goal is to help dental labs, and especially small labs to lower their cost for supplies, provide business opportunities, and generate growth. Attend their upcoming Gro3X Gem Talks on November 5th in Charlotte, NC (https://www.gro3x.com/collections/family/products/gro3x-gem-talks). Gro3X Gem Talks is an all day marketing symposium in Ted-Talk style featuring some 10+ lab speakers as they share their most relevant and practical marketing techniques. We will hear from Sasha der Avanessian from Harvest Dental (https://harvestdental.com/), Anne Kelzer from AMK Dental Lab (https://www.facebook.com/people/AMK-Dental-Lab/100028120884702/), Frankie Acosta from AA Dental Design (https://www.aadentaldesign.com/) and Ricki Braswell from Beyond Coaching (https://www.transitionbeyond.com/) and former Co-Executive Director of the NADL. All of them will talk about real marketing as it is done in their own labs and businesses every day. Register now at gro3x.com to take advantage of their early bird special of only $95. Enter discount code VFTB for Voices from The Bench and receive an extra 10% discount, just because you listen to this Podcast. Special Guest: Eric Kukucka DD.

What A Crime to Be Alive
Episode 35 - Las Cruces Bowling Alley Massacre

What A Crime to Be Alive

Play Episode Listen Later Sep 16, 2021 39:45


Thanks for listening! Please subscribe, share, rate and review! The Las Cruces Bowling Alley Massacre involved the robbery of Las Cruces Bowl and the shooting of seven people that left four victims dead in Las Cruces, NM in 1990. The case remains unsolved and was still being actively investigated as of 2015. FB: https://www.facebook.com/WhatACrimePod Twitter: https://twitter.com/whatacrimepod Instagram: https://www.instagram.com/whatacrimepod Email: whatacrimepod@gmail.com Sources: https://en.wikipedia.org/wiki/Las_Cruces_bowling_alley_massacre https://www.lcsun-news.com/story/news/2021/02/10/las-cruces-bowling-alley-massacre-teran-family-speaks-unsolved-shooting/4452287001/ https://unsolvedmysteries.fandom.com/wiki/Las_Cruces_Bowling_Alley_Massacre https://www.amazon.com/Nightmare-Las-Cruces-Charlie-Minn/dp/B0051V0I0K https://www.lascrucesbulletin.com/stories/brother-can-never-get-over-it,5742 https://www.upi.com/Archives/1990/02/12/Laboratory-experts-search-for-clues-in-bowling-alley/7337634798800/ https://www.lcsun-news.com/story/news/local/2020/02/09/las-cruces-bowling-alley-massacre-unsolved-30-years-later/4700803002/ https://www.cnn.com/2015/02/05/us/bowling-alley-massacre-anniversary/index.html https://soundcloud.com/crucessunnews/las-cruces-bowling-alley-massacre-911-call-full-audio https://www.nbcnews.com/news/us-news/south-carolina-man-charged-assisted-suicide-shooting-alex-murdaugh-n1279208?utm_source=facebook&utm_medium=news_tab&utm_content=curated

Epigenetics Podcast
Heterochromatin Protein 1 and its Influence on the Structure of Chromatin (Serena Sanulli)

Epigenetics Podcast

Play Episode Listen Later Sep 16, 2021 31:23


In this episode of the Epigenetics Podcast, we caught up with Serena Sanulli from Stanford University to talk about her work on Heterochromatin Protein 1 (HP1), the structure of chromatin on the atomic-scale and the meso-scale, and phase separation. The Laboratory of Serena Sanulli is interested in finding connections between changes that happen on the nucleosomal level and the resulting impact on chromatin conformation on the meso-scale. They combine methods like NMR and Hydrogen-Deuterium Exchange-MS with Cell Biology and Genetics. This enables them to dissect how cells use the diverse biophysical properties of chromatin to regulate gene expression across length and time scales. A second focus of the lab is HP1, which interacts with the nucleosome and changes its conformation, enabling the compaction of the genome into heterochromatin, effectively silencing genes in that region. A high concentration of HP1 leads to the phenomenon of phase separation in the nucleus, which the Sanulli lab is now investigating.   References Sanulli, S., Justin, N., Teissandier, A., Ancelin, K., Portoso, M., Caron, M., Michaud, A., Lombard, B., da Rocha, S. T., Offer, J., Loew, D., Servant, N., Wassef, M., Burlina, F., Gamblin, S. J., Heard, E., & Margueron, R. (2015). Jarid2 Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation. Molecular Cell, 57(5), 769–783. https://doi.org/10.1016/j.molcel.2014.12.020 Sanulli, S., Trnka, M. J., Dharmarajan, V., Tibble, R. W., Pascal, B. D., Burlingame, A. L., Griffin, P. R., Gross, J. D., & Narlikar, G. J. (2019). HP1 reshapes nucleosome core to promote phase separation of heterochromatin. Nature, 575(7782), 390–394. https://doi.org/10.1038/s41586-019-1669-2 Sanulli, S., & Narlikar, G. J. (2021). Generation and Biochemical Characterization of Phase‐Separated Droplets Formed by Nucleic Acid Binding Proteins: Using HP1 as a Model System. Current Protocols, 1(5). https://doi.org/10.1002/cpz1.109   Related Episodes Transcription and Polycomb in Inheritance and Disease (Danny Reinberg) Heterochromatin and Phase Separation (Gary Karpen)   Contact Active Motif on Twitter Epigenetics Podcast on Twitter Active Motif on LinkedIn Active Motif on Facebook Email: podcast@activemotif.com

WQA Radio
WQA Radio #232 - WQA Grand Opening

WQA Radio

Play Episode Listen Later Sep 15, 2021 10:36


Welcome to WQA Radio. In this episode, we'll hear from the speakers at the grand opening of the new WQA International Headquarters and Laboratory in Lisle, Illinois.

Outspoken with Shana Cosgrove
I'm Speaking: Jennifer Banwart, U.S. Senate Candidate for NC.

Outspoken with Shana Cosgrove

Play Episode Listen Later Sep 14, 2021 78:18


Changing the World, Authenticity, and It's PossibleIn this episode of The Outspoken Podcast, host Shana Cosgrove talks to Jennifer Banwart, U.S. Senate Candidate for North Carolina. Jennifer talks about what it's like running for Senate and what all compelled her to get into politics. She also touches on her college experience and the bold personal decision she made to build herself a valuable foundation. Additionally, we get to hear about Jennifer's experience with the NSA, her decision to leave the government, and how she went from living a private life to being up front in the public eye. QUOTES “Intelligence is messy. People have to be comfortable with that if they're going to thrive in it.” - Jennifer Banwart [46:53]  “You can see that if you start to do things in a certain way, other people will start to do things a certain way and eventually you're changing the world. And you have to believe that that is true. It's possible.” - Jennifer Banwart [67:34]  “I've always tried to be kind, as much as I could. And sometimes my kindness has been mistaken for weakness and I'm not afraid to come out and show it when I need to. But I've always tried to come from a place of remembering my manners, respecting other people, being humble and believing that there's something bigger than me, but be firm. Be pragmatic, but be firm.”– Jennifer Banwart [71:45] TIMESTAMPS  [00:04] Intro [03:09] Shana and Jennifer [06:25] Working for and Leaving the Government [08:36] Family Meetings and Listening [11:03] Growing Up and Family [16:54] Early Interest in Politics [18:34] Deciding on College [21:25] American University [24:17] Nyla Technology Solutions [24:50] Energy and Bob Dole's Campaign [27:57] Transferring to Whitman [32:04] Work After College [35:16] Student Debt [35:54] Meeting Recruiters and Deciding [37:24] Marriage and Having Children [38:17] Interviewing at NSA and CIA [39:10] Jennifer's Career at NSA [44:40] National Counterterrorism Center [46:59] Jennifer's Christmas Card [48:01] Running for Senate [52:13] Moderate Republican [54:27] It's Possible [59:40] Overview of Jennifer's Campaign [67:47] Private Life to Public Eye [70:48] Wrap Up Questions [77:57] Outro RESOURCES https://www.defense.gov/ (U.S. Department of Defense) https://military.wikia.org/wiki/Secretary_of_Defense_Medal_for_Valor (Secretary of Defense Medal for Valor) https://ncsu-las.org/ (Laboratory for Analytic Sciences) https://www.ncsu.edu/ (NC State University) https://www.casio.com/products (Casio) https://www.imdb.com/title/tt0083413/ (Family Ties) https://www.sesamestreet.org/ (Sesame Street) https://www.imdb.com/title/tt0066651/ (The Electric Company) https://www.whitehouse.gov/about-the-white-house/presidents/ronald-reagan/ (Ronald Reagan) https://joffrey.org/ (Joffrey Ballet) https://www.nyu.edu/ (NYU) https://www.american.edu/ (American University) https://history.house.gov/People/Detail/13850 (Newt Gingrich) https://www.bobdole.org/ (Bob Dole) https://www.urbanoutfitters.com/?ref=logo (Urban Outfitters) https://washington.org/dc-insider-newsletter (DC Insider) https://www.whitman.edu/ (Whitman College) https://www.python.org/ (Python) http://www.sqlcourse.com/intro.html (SQL) https://www.olivegarden.com/home (Olive Garden) https://www.cia.gov/ (CIA) https://www.nsa.gov/ (NSA) https://www.dni.gov/index.php/nctc-home (National Counterterrorism Center) https://www.linkedin.com/in/michaelleiter/ (Michael Leiter) https://www.burr.senate.gov/ (Senator Burr) https://www.fec.gov/ (Federal Election Commission) https://www.nelsonmandela.org/ (Nelson Mandela) https://tim.blog/about/ (Tim Ferriss) https://www.cruz.senate.gov/ (Ted Cruz) https://digitalarchive.wilsoncenter.org/resource/cold-war-history/vaclav-havel (Václav Havel) RELEVANT LINKS https://www.linkedin.com/in/jenbanwartjen4sennc/ (Jennifer Banwart) on LinkedIn https://twitter.com/jen4sennc?lang=en (Jennifer Banwart) on...

Voices from The Bench
181: Giving Back with the Dental Lifeline Network and Hollie Stevenson

Voices from The Bench

Play Episode Listen Later Sep 13, 2021 57:31


Every day. Every day we improve people's lives. From single tooth to full mouth, we get to make a difference in the oral health and wellbeing of patients. But imagine if you could do more with very little extra work. Now you can! Hollie Stevenson from the Dental Lifeline Network (Donated Dental Services) (https://dentallifeline.org/) comes on the podcast to talk about how labs, along with dentist and specialist, can take less fortunate patients and turn their lives around. Hollie talks about how the program works, how labs can get involved, and shares a few stories from patients who have benefited from the generosity of those to participate. SIGN UP YOUR LAB TODAY! (https://dentallifeline.org/our-volunteers/volunteer-now/) COME SEE RECORD WITH US: At the Preat (https://preat.com/) booth during the Eastern Conference of Dental Laboratories = September 24 & 25, 2021 in Winston-Salem, NC (http://www.eastern-conference.com/index.html) Again at the Preat (https://preat.com/) booth during the Whip Mix Digital Forum = October 29 & 30, 2021 in Louisville, KY (https://www.whipmix.com/special-events/2021-digital-forum/) Gro3X (https://www.gro3x.com/) is a dental supply, service and marketing company that was founded by Norbert Ulmer and their goal is to help dental labs, and especially small labs to lower their cost for supplies, provide business opportunities, and generate growth. Attend their upcoming Gro3X Gem Talks on November 5th in Charlotte, NC (https://www.gro3x.com/collections/family/products/gro3x-gem-talks). Gro3X Gem Talks is an all day marketing symposium in Ted-Talk style featuring some 10+ lab speakers as they share their most relevant and practical marketing techniques. We will hear from Sasha der Avanessian from Harvest Dental (https://harvestdental.com/), Anne Kelzer from AMK Dental Lab (https://www.facebook.com/people/AMK-Dental-Lab/100028120884702/), Frankie Acosta from AA Dental Design (https://www.aadentaldesign.com/) and Ricki Braswell from Beyond Coaching (https://www.transitionbeyond.com/) and former Co-Executive Director of the NADL. All of them will talk about real marketing as it is done in their own labs and businesses every day. Register now at gro3x.com to take advantage of their early bird special of only $95. Enter discount code VFTB for Voices from The Bench and receive an extra 10% discount, just because you listen to this Podcast. Whip Mix (https://whipmix.com/) is very excited to announce the new PRO 4K large format 3D printer from Asiga. It's ideal for printing any kind of model, dentures, splints, surgical guides, impression trays and more. The Asiga Pro 4K DLP printer (https://whipmix.com/products/asiga-pro-4k/) is priced at under $25,000, has a large build plate and is available in both 65µm and resolution versions. For information about the Asiga Pro 4K, visit www.whipmix.com or call Chris Frye at (513) 680-1512. Special Guest: Hollie Stevenson.

Trick or Treat Radio
TorTR #476 - The Pancake Man Made Me Do It

Trick or Treat Radio

Play Episode Listen Later Sep 10, 2021 173:00


On the trail of a missing opinion, an old friend comes across a secretive group attempting to summon a terrifying supernatural entity that will help his friend discover his true feelings about a film. On Episode 476 of Trick or Treat Radio we are joined by our old friend Ghetto Tim to talk about the Fantasia Film Fest and to also discuss the film The Empty Man from first time feature director David Prior! We also discuss the most depraved zombie movie of all time, the final film 20th Century Fox produced, and films to keep an eye on over the next year. So grab your favorite syrup, wade through the thick miasma, and strap on for the world's most dangerous podcast!Stuff we talk about: RIP Art Metrano, Taxidermia, MZ's Coffin Corner, Judge William B Keene, Police Academy, Jim Varney in drag, The Three Stooges, hashpipe alley, History of the World Part I, Macho Man Randy Salvage, Gilbert Gottfried's Amazing Colossal Podcast, Mario Cantone, RIP Michael K. Williams, Hap and Leonard, RIP Daffney, Steampipe Alley, Towering Inferno, Irwin Allen, Krypton, Genndy Tartakovsky, Andrei Tarkovsky, Dexter's Laboratory, Peter Lorre, Ken Burns Cartoon Documentaries, Jodorowsky's Hungry Hungry Hippos, Fahrenheit 451, Soylent Green, See Hear Podcast, Woodstock ‘99, Fantastic Fest, ICP and Gwar documentaries, Songwriter, Rock & Rule, Fantasia Film Fest, great international films, Joe Bob Briggs' The Last Drive-In, The Sadness, Suicide Squad, Charlotte Film Fest, Woodlands Dark and Days Bewitched, Kier-La Janisse, Severin, Mad God, Phil Tippet, Alien on Stage, Christopher Guest, The Infinite Two Minutes, Tenet, The Spine of Night, Junkhead, Cat 3, Philosophy of Knife, Taiwanese Horror, Raven Banner, Uzumaki, The Boxer's Omen, Shaw Brothers, Montreal Canada, Hellbenders, Glass House, Field Sobriety Test, white eye patches, Hollywood Salvage, David Prior, David Fincher, The Empty Man, bowl of chili analogy, Cullen Bunn, Boom! Studios, Kill List, Carpenter, Raimi, the meaning of miasma, Kubrick, the last 20th Century Fox Film, Cronenberg, Lovecraft, cosmic horror, long opening sequences, Lustmord, Nomads, Beyond the Black Rainbow, Panos Cosmatos, In the Mouth of Madness, Angel Heart, Hereditary, The Ring, Nietzsche, Monique and Unique, Emmanuel Lewis, 2001: A Space Odyssey, Raw Force, creepypasta, Savageland, the Tubi Pimp, Weng's Chop, An Exemption to Life, and The Pancake Verdict.Support us on Patreon: https://www.patreon.com/trickortreatradioJoin our Discord Community: https://discord.gg/ETE79ZkSend Email/Voicemail: mailto:podcast@trickortreatradio.comVisit our website: http://trickortreatradio.comStart your own podcast: https://www.buzzsprout.com/?referrer_id=386Use our Amazon link: http://amzn.to/2CTdZzKFB Group: http://www.facebook.com/groups/trickortreatradioTwitter: http://twitter.com/TrickTreatRadioFacebook: http://facebook.com/TrickOrTreatRadioYouTube: http://youtube.com/TrickOrTreatRadioInstagram: http://instagram.com/TrickorTreatRadioSupport the show (https://www.patreon.com/trickortreatradio)

99% Invisible
457- Model Organism

99% Invisible

Play Episode Listen Later Sep 7, 2021 31:53


Axolotls are nature's great regenerators. They are able to grow back not just their tails, but also legs, arms, even parts of vital organs, including their hearts. This remarkable ability is one of several traits that turned the axolotl into a scientific superstar. The axolotl is one of the most abundant laboratory animals in biology. They can be found swimming in tanks at universities all around the world. But in the wild they've only ever been found in one place: Mexico City.Model Organism

You Might Be Wondering How We Got Here
NOAH Vol. II: Issue 4: Enter The Mad Scientist‘s Laboratory

You Might Be Wondering How We Got Here

Play Episode Listen Later Sep 7, 2021 100:35


Check out our Patreon! https://www.patreon.com/YMBWPodcast Our heroes have successfully infiltrated the evil Dr. Eclipse's Monstorous Laboratory. What terrors will our heroes encounter there? Will the Eclipse sister Luna betray our heroes? Will the Chipster perish? Will Brooke Free get any good photos? Find out in this issue of NOAH! You Might Be Wondering How We Got Here is part of the Frolic Podcast Network. You can find more outstanding podcasts to subscribe to at Frolic.media/podcasts! Check us out on our social media! https://twitter.com/ymbwpodcast https://www.instagram.com/ymbwpodcast/ Check out all of our other stuff! https://linktr.ee/ymbwpodcast

Wow in the World
Back to School WeWow Day 2

Wow in the World

Play Episode Listen Later Aug 24, 2021 9:46


It's Day 2 of our special Back to School Edition of WeWow! Bring your critical thinking skills to the Laboratory of Bad Ideas, because today we're identifying problems and solutions for recess! Then, check back tomorrow for even more projects you can tinker with like a real scientist.

The Devin Nunes Podcast
California: Socialism's Laboratory

The Devin Nunes Podcast

Play Episode Listen Later Aug 20, 2021 25:56


GET REAL with Peniel, BM, and Ashley Choi
Ep. #4 | Eating Kimchi (~metaphorically~) with CORBYN from 28 LABORATORY

GET REAL with Peniel, BM, and Ashley Choi

Play Episode Listen Later Aug 19, 2021 62:53


Good friend of the podcast, CORBYN from 28 LABORATORY, is back to chat about his new single "Dante's Valley" and how being raised in two cultures impacted his upbringing. Real deep stuff. Eat your kimchi, kids. Thank you BetterHelp for sponsoring this episode! Get 10% off your first month by visiting betterhelp.com/getreal10 If you enjoyed this episode, make sure to subscribe to @thedivestudios (IT'S FREE) and leave a comment, rating and/or review on Spotify, Apple Podcasts, Soundcloud, and YouTube. To find out more about MINDSET by DIVE Studios, visit here: https://www.getmindset.com/ Download the MINDSET by DIVE Studios app at https://bit.ly/3xjGFin Episodes are presented by @thedivestudios Connect with us on all social media platforms and at http://www.divestudios.io/! SUPPORT & JOIN DIVE Studios' Patreon: https://www.patreon.com/divestudios JOIN DIVE Studios' Discord Channel: https://discord.gg/nnYX2E4 Connect with Ashley: https://www.instagram.com/ashleybchoi/ Connect with Peniel: https://www.instagram.com/btobpeniel/ Connect with JUNNY: https://www.instagram.com/jnkmsc/ Special thanks to Corbyn! https://www.instagram.com/corbyn28lab/ https://twitter.com/corbyn_28lab/ #GETREAL #DIVEStudios #Kpop #AshleyChoi #애슐리 #PenielShin #프니엘 #BTOB #JUNNY #주니 #Corbyn #28LABORATORY Learn more about your ad choices. Visit megaphone.fm/adchoices