This Probably Doesn't Matter

Brian, Katie, and I sit down with Vince Fuoco, a pharmacist from the greater Seattle area. We discuss a wide range of medication-related issues, including Coronavirus, dieting and nutrition, the placebo effect, the opioid crisis, and mental health. We also delve into a few less-scientific topics, drink fantastic beer from Geaux Brewing in Auburn, and much more! Recorded March 7th, 2020 at the TPDM studio in Wenatchee, Washington. Check out Vince Fuoco's podcast: Pick A Topic https://anchor.fm/vincent-fuoco/ Geaux Brewing -- Auburn, WA http://www.geauxbrewing.com/   EPISODE NOTES: Peramivir — an antiviral injection for treating influenza https://www.fda.gov/drugs/information-drug-class/rapivab-peramivir-information The Game Changers (documentary) https://en.wikipedia.org/wiki/The_Game_Changers The Complete Guide to Fasting: Heal Your Body Through Intermittent, Alternate-Day, and Extended Fasting (book by Jason Fung and Jimmy Moore) https://www.amazon.com/Complete-Guide-Fasting-Intermittent-Alternate-Day/dp/1628600012 https://www.dietdoctor.com/intermittent-fasting/guides Angus Barbieri's record-breaking fast https://en.wikipedia.org/wiki/Angus_Barbieri%27s_fast The Placebo Effect https://www.webmd.com/pain-management/what-is-the-placebo-effect Eddy Merckx — Belgian cycling legend https://en.wikipedia.org/wiki/Eddy_Merckx Magic Bullet Effect (medicine) http://broughttolife.sciencemuseum.org.uk/broughttolife/techniques/magicbullet Cure for Hepatitis C https://www.mayoclinic.org/medical-professionals/digestive-diseases/news/most-patients-with-hcv-cured-with-new-drugs-but-at-what-price/mac-20430491 Avandia (rosiglitizone) https://en.wikipedia.org/wiki/Rosiglitazone https://blogs.scientificamerican.com/observations/avandia-restricted-in-u-s-banned-in-europe/ Heroin marketed for children in the early 1900's https://www.narconon.org/drug-information/heroin-history-1900s.html The Pharmacist (documentary) https://www.netflix.com/title/81002576 Cigarette advertisements featuring physicians https://www.healio.com/hematology-oncology/news/print/hemonc-today/%7B241d62a7-fe6e-4c5b-9fed-a33cc6e4bd7c%7D/cigarettes-were-once-physician-tested-approved Washington State prescriptive authority for Narcan https://www.wsparx.org/page/NaloxoneOpioid https://stopoverdose.org/naloxone-law-in-washington/ Supervised consumption services in Switzerland JRE #1250 — Johann Hari https://www.youtube.com/watch?v=CDpjvFn4wgM&t=1722s Medical Heroin program in Norway https://www.theguardian.com/world/2018/aug/10/norway-trials-free-heroin-prescriptions-for-most-serious-addicts Ibogaine Therapy for drug addiction https://maps.org/research/ibogaine-therapy Ibogaine for treatment of alcoholism — clinical trial in Brazil https://www.clinicaltrials.gov/ct2/show/NCT03380728 Jay Greenberg — prolific composer and cello prodigy twice featured on 60 minutes https://en.wikipedia.org/wiki/Jay_Greenberg_(composer) Daniel Tammet — British man who memorized over 22,000 digits of Pi (π) https://www.sciencemag.org/news/2005/04/man-who-memorized-pi Medical Cannabinoids for Cancer Cachexia https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360413/ Marinol — brand name for dronabinol, a specific type of THC used for chemotherapy-induced nausea/vomitting https://en.wikipedia.org/wiki/Dronabinol https://medlineplus.gov/druginfo/meds/a607054.html Notes from Brian: Lisinopril is not a duretic. It's an angiotensin-converting enzyme (ACE) inhibitor. Furosemide is an example of a duretic which would have a fluid-reducing effect. The New England Patriots started four different quarterbacks in 1992. Hugh Millen, who played for the University of Washington in 1985, led the '92 Patriots in passing yards. Drew Bledsoe played high school football for the Walla Walla Blue Devils, not the Prosser Mustangs. https://www.thisprobablydoesntmatter.com/

Katie and I sit down with local comedian Michael Lee Miller to discuss her novel I Should Have Worn Panties and take a simultaneously hilarious and riveting look at her truly unique past and present — from an unbelievable childhood to her blossoming comedy career and adventures as the mother of three beautiful children. We've got endless laughs, wild stories, and much more!   If you missed her performance as part of a sold-out Cold Winter Nights on February 14th at the Numerica Performing Arts Center in Wenatchee, be sure to catch any and all of her upcoming performances. Michael also hosts the region's best trivia night, so if you're ever at the East Wenatchee Buzz Inn on a Tuesday, prepare to experience a thoroughly enjoyable and innovative test of your cerebral cortex! Grab your copy of the book at: https://www.amazon.com/I-Should-Have-Worn-Panties/dp/1731199929       

Ando Peart and Matt Smith of Snatchee Records sit down with Katie and I to discuss the revival of Wenatchee's music scene, detail what it takes to run a local record label, share stories from Wally's House of Booze and much more!   Facebook: https://www.facebook.com/SnatcheeRecords509/ Bandcamp: https://snatcheerecords.bandcamp.com/

Daniel Benoit joins Katie and I to talk music and skateboarding, daydream of sail-boating, and discuss food poisoning as a necessary risk to enjoying Taco Bell. We dive deep into the history of horror films, reminisce about recurrent dreams, reveal a new segment of the podcast, revel in the return on the lightning round, and much, much more.  

Jake St. John, Tiffany Shafer, and David Betancourt of Wenatchee-based goth-rock/post-punk band Datura sit down with Katie and I to discuss their musical histories, creative processes, and preview some upcoming shows. We talk about how the Wenatchee music scene has evolved over the years, I reveal my all-time favorite teacher, Katie explains why she's not a virtuoso pianist, and much more! Check out their November 1st show with Children In Heat and The Crushers at Wally's House of Booze in Wenatchee. Make sure to visit Datura's bandcamp page, where you'll find their debut Orphans EP. https://daturapnw.bandcamp.com/releases

Brian, Geoff and I survive a dangerous motor-vehicle accident thanks to my million-dollar maneuvers, while Judy Knapp's calm under pressure helps us make it to Joe Rogan and Dave Chappelle's sold-out comedy show at the Tacoma Dome. Recorded in the wee hours of August 3rd, 2019 at the exquisitely trashy Travelodge in Tacoma. Post-wreck analysis, post-show antics, and much more!

Brian, Geoff and I bring TPDM to the Hitching Post Tavern in Cashmere for a Greater Heights presentation: The Blender 004. This monthly event's installment features live music by acoustic singer/songwriter Indigo Rose, instrumental prog rock trio Himiko Cloud, party doom duo Ghost Power!!! and electronic bass master Mob Dole. Recorded on July 27th, our evening-long journey also includes artist interviews, plenty of shenanigans, incredibly fun times, and much more!   0:00:00 -- Introduction 0:01:05 -- pre-show with Ghost Power!!! and Greater Heights 0:17:08 -- Indigo Rose 1:17:07 -- 'you're about to get soaked in it' 1:19:37 -- Himiko Cloud 2:03:14 -- interview with Indigo Rose 2:12:18 -- 'would you rather?' 2:15:58 -- Ghost Power!!! 2:57:07 -- 'hey Geoff, check this microphone' 3:00:59 -- interview with Himiko Cloud 3:09:50 -- Mob Dole 3:35:32 -- Closing Thoughts

Shai, Kelsey, Katie and I sit down and talk about comedy production in Central Washington, the culture shock in moving from Los Angeles to the shores of Lake Chelan, finding true love through technology, and much much more! Shai Newaz and Kelsey Guy are the brilliant minds behind and owners of Rotten Apple, a premier entertainment company bringing nationally-acclaimed comedians to Central Washington since 2018.   https://rottenapplepresents.com/ https://www.facebook.com/rottenapplecrew https://thisprobablydoesntmatter.com/  

Katie, Allie, Cory and I sit down and talk about the cannabis industry. Cory and Allie are co-owners of The Happy Crop Shoppe and are sponsoring the upcoming comedy show on June 28th at the RadarStation in Wenatchee. Be sure to get your tickets now!   http://thisprobablydoesntmatter.com

Katie, Matthew and I sit down and talk about the theater, losing weight, Matthew's time in New York, how we all met our spouses, and much much more. http://thisprobablydoesntmatter.com

Katie and I sit down and Talk with Russian pop group Bosaya! We talk about: Troy's travels in Russia, Bosaya's experience in the U.S, Galina's performances at  2008, and 2014 Olympic games, and much much more. 

Bandits of The Animal Kingdom join Katie and I in Studio! Danny and Amanda sit and talk with us about their travels around the United States (and beyond), Playing in a band as a couple, the local music scene, and much much more.    https://www.facebook.com/banditsoftheanimalkingdom/ https://thisprobablydoesntmatter.com

Brian DeShazo, Katie and I sit down and talk about mushrooms, pharmacy, dropping out of college, the Kentucky Derby and much more.  Don't forget to hop on the mailing list to keep up to date on upcoming event!  thisprobablydoesntmatter.com

Devils Gulch and the Missionaries are in Studio! Katie and I sit down and talk with the band about music, interpersonal relationships, preforming live, musical goals, who's turn it is, and much much more. Don't miss this one, chaos ensues.  https://www.facebook.com/DevilsGulchandTheMissionaries/  https://www.thisprobablydoesntmatter.com

Andrew Houck and Mitch Wixom of Ghost Power!!! sit down with Katie and I to discuss: their band, music, crazy moments on stage, various performance related injuries, drinking and much much more! Check out the band at: https://www.facebook.com/Ghostpowermusic/ https://thisprobablydoesntmatter.com

Alex Haley, Katie and I sit down and talk about: Comedy, influences and inspiration,  booking shows, writing styles, drinking and much more.  check out thisprobablydoesntmatter.com And LAPH: https://www.facebook.com/LiveLaphLove/  

Connor Dahlin, Katie and I sit down and talk about: Connor's move to the northwest, poetry & writing, and the nuts and bolts of his writing process and much more!  

Laine Heikel, Katie, and I sit down and talk about me bombing on stage recently, how Laine got into comedy and our comedy influences, whether or not there is such a thing as  a 'white lie' and lots more!   

Ethan Starkey, Katie, and I sit down and discuss: wild cats, music & songwriting, speech patterns, and a narcissistic ex girlfriend. Ethan also breaks out the guitar and plays some original music!  https://soundcloud.com/ethanstarkey thisprobablydoesntmatter.com   

Loren, Katie and I sit down and talk about comedy, his time as a youth pastor, the y2k scare, being punched in the face and more!   thisprobablydoesntmatter.com

Jason, Katie and I sit down and talk about Jason's time in the army, local comedy, magic, news and lots more! thisprobablydoesntmatter.com for tickets to the show march 22!

Brian DeShazo and I sit down and discuss objects falling from the sky, bigfoot and aliens, animals in captivity, sports (in 90 seconds), the news from Angola and much more.  Remember to check out our website thisprobablydoesntmatter.com  

TPDM: David and I sit down and discuss: Valentine's Day, current news, local burgers and much more.