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Immunology is a key area in biotech and biopharma, both in terms of R&D and sales.However, according to UK-headquartered Greywolf Therapeutics, the industry has only focused on two-thirds of the puzzle.To have an immunological effect, you must activate the body's T cells, which cells requires a chain of three key signals. The first is antigen recognition, i.e. the initial detection of a cell by a T-cell. The second is the co-stimulation of non-antigen presenting molecules, which enhances the immune response. The final step is cytokine-mediated differentiation and expansion, which guides how T-cells target threats. Companies have focused on the second two signals, with signal 2 most commonly seen in therapies such as checkpoint inhibitors and monoclonal antibodies. Signal 3, on the other hand, can be primarily seen in therapies for autoimmune disorders, such as anti-TNF and JAK inhibitors.Greywolf Therapeutics is the first company to explore changing signal 1. The company says focusing on signal 1 applies in three key therapeutic areas: oncology, autoimmunity and virology. Greywolf's first candidate has delivered a robust response during its ongoing phase I/II trial in oncology, therefore demonstrating proof-of-mechanism and target engagement, with its next candidate well-progressed in preclinical development in autoimmunity.To tell us more about the company and its work is Pete Joyce, CEO and co-founder of Greywolf Therapeutics.01:19-04:12: About Greywolf Therapeutics04:12-04:51: The origins of the name04:51-06:52: The three ‘signals' of the mechanics of immunological responses06:52-08:31: Treatments associated with each signal08:31-10:09: Why is step 1 important, and why has it not been investigated for treatments?10:09-11:28: What areas of disease is this applicable to?11:28-12:19: How do you inhibit ERAP?12:19-14:01: Greywolf Therapeutics' candidates14:01-15:11: How is this an advance on current treatments?15:11-16:05: What is success for patients?16:05-17:20: How does the stage of disease affect treatment?17:20-18:09: Are other companies looking into antigen modulation? 18:09-19:47: Has this led to investment opportunities?19:47-21:15: Next steps21:15-21:55: Do you anticipate more interest in this space?21:55-23:21: Attending events Interested in being a sponsor of an episode of our podcast? Discover how you can get involved here! Stay updated by subscribing to our newsletter
A conversation with Prof Wataru Kusaka of Tokyo University of Foreign Studies.
Please donate to the show! Today we will discuss shelter, including legislation such as ERAP and RAFT, the current policy sphere, how it has changed, how it affects cities and towns, and how Governor Healy has been engaging with this issue.City Councilor Etel Haxhiaj joins Jordan Berg Powers, Jonathan Cohn, and Anna Callahan to chat about Massachusetts politics. This is the audio version of the Incorruptible Mass podcast, season 5 episode 58. You can watch the video version on our YouTube channel. You're listening to Incorruptible Mass. Our goal is to help people transform state politics: we investigate why it's so broken, imagine what we could have here in MA if we fixed it, and report on how you can get involved. To stay informed:* Subscribe to our YouTube channel* Subscribe to the podcast (https://incorruptible-mass.buzzsprout.com)* Sign up to get updates at https://www.incorruptiblemass.org/podcast* Donate to the show at https://secure.actblue.com/donate/impodcast
This week we continue delving into community-rooted disaster relief in California, from wildfires to the pandemic. From building mutual aid networks, to translating emergency messages in common local languages, we see in action the incredible difference language justice can make in our communities. In Sonoma County, organizers hit the field with information on where to get food, shelter, and support. In San Francisco, they set up a much needed support response to COVID-19 in the city's Mission District. Tune in and hear how these leaders act collectively to confront those in power, work for justice, and together answer one vital question: how can next time be different? Special thanks to Sonya Green. Thank you to the But Next Time team. To listen to all of the But Next Time episodes and access video versions with Spanish subtitles visit www.butnexttime.com. You can also learn more about the organizations featured in the podcast and access resources like a listening and discussion guide. Learn more about the story and find the transcript on makingcontactradio.org. Like this story? Support independent journalism, NewsMatch will double your donation up to $1,000! Making Contact is an award-winning, nationally syndicated radio show and podcast featuring narrative storytelling and thought-provoking interviews. We cover the most urgent issues of our time and the people on the ground building a more just world. But Next Time was created as part of Rise-Home Stories, a project in which multimedia storytellers and housing, land, and racial justice advocates came together to reimagine the past, present, and future of our communities by transforming the stories we tell about them. The Rise-Home Stories Project includes five pieces of media (a video game, children's book, animated short, and online storytelling site, and the But Next Time Podcast) that help us rethink our relationships to land and home. For more info visit www.risehomestories.com FEATURING: Alma Bowen, Founder / Executive Director of Nuestra Comunidad, Maribel Merino, Host, Radio Autóctona Indigenista on KBBF, Xulio Soriano, California Rural Legal Assistance, Mariano Alvarez, California Rural Legal Assistance, Gervacion Peña Lopez, Host, Radio Autóctona Indigenista on KBBF, Beatrice Camacho, ERAP manager of North Bay Organizing Project, Valerie Tulier-Laiwa, Coordinator of the Latino Task Force BUT NEXT TIME: This episode is hosted by Chrishelle Palay and Rose Arrieta, and produced by Leah Mahan. MAKING CONTACT: This episode is hosted by Anita Johnson and produced by Anita Johnson, Lucy Kang, Salima Hamirani, and Amy Gastelum. Our executive director is Jina Chung. MUSIC: All original compositions by Fernando Arruda including “But Next Time,” “Going Back,” and “Rumors of Hope.” Learn More: But Next Time Podcast Rise Home Stories Working Films
Today we'll be speaking with Grey Wolf Therapeutics to hear about their astounding work with ERAP inhibition to target antigen presentation in tumour cells. This novel direction is broadly applicable across many tumour types, and we'll learn about exciting exploration of the peptide library to develop specific therapies along with potential next steps for pairing with T-cell treatment.
OPINION: Not just a promise: Erap ordered pullout of second grounded vessel | August 21, 2023Subscribe to The Manila Times Channel - https://tmt.ph/YTSubscribe Visit our website at https://www.manilatimes.net Follow us: Facebook - https://tmt.ph/facebook Instagram - https://tmt.ph/instagram Twitter - https://tmt.ph/twitter DailyMotion - https://tmt.ph/dailymotion Subscribe to our Digital Edition - https://tmt.ph/digital Check out our Podcasts: Spotify - https://tmt.ph/spotify Apple Podcasts - https://tmt.ph/applepodcasts Amazon Music - https://tmt.ph/amazonmusic Deezer: https://tmt.ph/deezer Stitcher: https://tmt.ph/stitcherTune In: https://tmt.ph/tunein#TheManilaTimes Hosted on Acast. See acast.com/privacy for more information.
HEADLINES: WPS mess blamed on post-Erap govts | Aug. 16, 2023 Subscribe to The Manila Times Channel - https://tmt.ph/YTSubscribe Visit our website at https://www.manilatimes.net Follow us: Facebook - https://tmt.ph/facebook Instagram - https://tmt.ph/instagram Twitter - https://tmt.ph/twitter DailyMotion - https://tmt.ph/dailymotion Subscribe to our Digital Edition - https://tmt.ph/digital Check out our Podcasts:Spotify - https://tmt.ph/spotify Apple Podcasts - https://tmt.ph/applepodcasts Amazon Music - https://tmt.ph/amazonmusic Deezer: https://tmt.ph/deezer Stitcher: https://tmt.ph/stitcherTune In: https://tmt.ph/tunein #TheManilaTimes#KeepUpWithTheTimes Hosted on Acast. See acast.com/privacy for more information.
Listen every weekday for a local newscast featuring town, county, state and regional headlines. It's the daily dose of news you need on Wyoming, Idaho and the Mountain West—all in four minutes or less. Fridays feature a roundup of KHOL's best stories of the week.
The Estrada government has always had a bad reputation for being corrupt, favoring family and friends, fighting between themselves in politics, failing to achieve their stated aims, and so on and so forth. Although they claimed Estrada would help the poor, they did little to implement the government program and actually make a difference in people's lives. It's a shame that after serving as president, Estrada will be known not as the man who did the most for the poor and disadvantaged, but as the first Philippine leader to face impeachment.Music:*Dark Woods by Colorfilm Music*24hr News by O2 StudioSound Bite:*PHILIPPINES: ESTRADA IMPEACHMENT TRIAL BEGINS (AP Archive YouTube Channel)Support the showGet a shout-out in an upcoming episode! Help me continue making great content for listeners everywhere. Go ahead, click the link for more details: https://www.buzzsprout.com/2027631/supportFollow me on:IG: https://www.instagram.com/philandrewpodcast/FB Page: https://www.facebook.com/philandrewpodcast
Anyone who's tried to buy a home or even lock down an affordable rental these days knows how tough the market has gotten. This week, Chris and Gabby are diving into New Mexico's affordable housing dilemmas. Donnie Quintana, the Director of the state's Emergency Rental Assistance Program, or ERAP, shares details about the state's Home Fund program, and the millions of dollars available to help people pay the bills. How long will these pandemic-era programs continue? Who qualifies for assistance? How can someone apply? Quintana explains how the money is being spent and safeguards in place to try and prevent fraud. We want to hear from you, our listeners! Leave us a review, and email the hosts at chris.mckee@krqe.com or gabrielle.burkhart@krqe.com with your story ideas or feedback. You can also catch us on Twitter, Facebook, or Instagram at @ChrisMcKeeTV and @gburkNM. For more on this episode and all of our prior episodes, visit our website: KRQE.com/podcasts.
Hamilton County Job & Families Services announced Wednesday July 27th that they are not accepting new Emergency Rental Assistance Program applications (ERAP) due to funding issues. Those who have already submitted applications for the program reportedly will not be affected. JFS said it is still processing those applications and will Read More Shared by United Resource Connection July 27, 2022
Subscribe to The Manila Times Channel - https://tmt.ph/YTSubscribe Visit our website at https://www.manilatimes.net Follow us: Facebook - https://tmt.ph/facebook Instagram - https://tmt.ph/instagram Twitter - https://tmt.ph/twitter DailyMotion - https://tmt.ph/dailymotion Subscribe to our Digital Edition - https://tmt.ph/digital Check out our Podcasts: Spotify - https://tmt.ph/spotify Apple Podcasts - https://tmt.ph/applepodcasts Amazon Music - https://tmt.ph/amazonmusic Deezer: https://tmt.ph/deezer Stitcher: https://tmt.ph/stitcherTune In: https://tmt.ph/tuneinSoundcloud: https://tmt.ph/soundcloud #TheManilaTimes Hosted on Acast. See acast.com/privacy for more information.
With the state-funded RAFT program, roughly 6,000 families are helped a year. With the federally-funded ERAP, more than 72,000 people got help.
It's been almost a year since Jefferson County launched its COVID-19 Emergency Rental Assistance Program. We talk with Nathan Salter in Workforce Development about what assistance has been provided, what funding is still available and about ERAP 2, which is coming down the road. As a reminder, details can be found on our website at: erap.jccal.org and if you have questions, you can contact one of our partner agencies at Birmingham Urban League at 205-326-0162, Neighborhood Housing Services of Birmingham at 205-328-4292, or Bridge Ministries at 205-930-0309.
The last remaining tenant protections against eviction for pandemic-related rent debt that were granted by the state are expiring at the end of the month. They were based on tenants having applied to the state's rent relief program, which according to a new study is slow to make decisions. The report indicates applicants are waiting months for the state program to make decisions on their cases, and that the majority of applicants have not received any payment. Still, the state should have enough funds to be able to pay every eligible applicant, even those who apply in the last weeks before the program closes.
As the moratorium for New York ends, there are neglectful landlords salivating at the thought of forcing thousands of families into destitution. The program known as ERAP may provide some protection from eviction but only just. We have fallen as a race, a species in fact, because we never learn from past mistakes. --- Send in a voice message: https://anchor.fm/mizzvee32/message
THE LEWDRESKY REAL | NO VOICE NO REASON | NEW YORK CITY | LONDON | UK
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Due to the impact of the pandemic, there have been a lot of programs that we have seen come out over the last couple of years. One that you have heard us talk about before... the PPP, the Paycheck Protection Program, which was set up to help business owners keep their people employed throughout the pandemic. Well, another program that was set up is called ERAP, the Emergency Rental Assistance Program, which is a Federal Grant intended to assist households who are unable to pay or are having difficulty paying rent and/or utilities due to the COVID-19 pandemic. Today on the show, we have invited Carrie Saites, a tenant that applied for these funds and has had some trouble with the program to come in and talk about her situation. We have also invited Samantha Gaddis from Contemporary Management Concepts, who is NOT Carrie's landlord, but is a local property management company that has lots of experience with this new Emergency Rental Assistance Program to shed some light on what Landlords have had to deal with as it pertains to the program. Listen in for an incredible episode and if you haven't done so already, please help us reach our goal of 1 THOUSAND subscribers on our YouTube Channel by the end of January! Click here: whoagnv.tv then press the RED "Subscribe" button! - - - - - Subscribe to my channel: https://www.youtube.com/channel/UCW1tLSw2Z5MB6Yebj_2pDJA?sub_confirmation=1 You can purchase custom WHOA GNV gear by visiting us here! - https://www.whoagnv.com/whoa-gnv-shop CHECK OUT OUR LAST EPISODE: E178: Fixing Dead Connections | Sebastian Galindo and Jake Nolan from Jungle | WHOA GNV Podcast https://youtu.be/WKrQub3iSME CONNECT WITH OUR GUEST: Samantha Gaddis of Contemporary Management Concepts Website: https://www.cmcapt.com/?utm_source=GoogleMyBusiness&utm_medium=organic&utm_campaign=GMB Carrie Saites: https://www.facebook.com/carrie.saites Know someone that would be PERFECT for our show? Nominate them here! https://www.whoagnv.com/nominate-a-guest/ LET'S BE FRIENDS: https://linktr.ee/collinaustin https://linktr.ee/whoagnv --- Support this podcast: https://anchor.fm/whoa-gnv-podcast/support
In Episode 5: We talk About CityFHEPS, we are joined by advocate Josefa Silva from Women In Need, Inc. (Win) who has been working in the non-profit sector on behalf of New York City's lowest income children and families for over fifteen years. She shares about CityFHEPS, a New York City rental assistance program to help individuals and families find and keep housing administered by the Department of Social Services. We dive into the eligibility requirements, application process, common challenges faced, and changes needed. Check out some of the resources discussed on the episode: CityFHEPS Application Documents: https://www1.nyc.gov/site/hra/help/cityfheps-documents.page CityFHEPS FAQ: https://www1.nyc.gov/assets/hra/downloads/pdf/cityfheps-documents/dss-7r-e.pdf How to Apply for Emergency Rental Assistance Program (ERAP): https://nysrenthelp.otda.ny.gov/en/Pages/18/how-to-apply-for-erap ERAP FAQ: https://otda.ny.gov/programs/emergency-rental-assistance/faq.asp Apply for ERAP: https://nysrenthelp.otda.ny.gov/en/ERAPApplication/StartOrResume Find a Homebase location: https://www1.nyc.gov/site/hra/help/homebase-locations.page Project Parachute: https://uploads-ssl.webflow.com/5f63cb56c583edef0cceb2ed/5fad4e5e8a65fab41a09cd19_Project%20Parachute%20FAQ.pdf To If you want toemail us you can at Nychearourvoices@gmail.comTwitter https://twitter.com/NYC_HOV?s=09 IG https://www.instagram.com/p/CT0Mg40r3t2/?utm_medium=share_sheet
Broome Renters And Landlords Receive $1.6M In ERAP Payments by WSKG News
Broome Renters And Landlords Receive $1.6M In ERAP Payments by WSKG News
Episodio/Podcast # 118 ¡Ayuda Para Inquilinos Y Dueños De Casa! ASISTENCIA PARA EL PAGO DEL ALQUILER (ERAP) Del Gobierno Bi
I accuse AviiChe and all women of genocide crimes of Mercy, the uterus, their husbands and the use of extortion to secure their non-rights over the rights they infringe on young. They are corrupted in the light and will suffer my vengeance for eternity of rape of their husband. The gay army military of Jesus and mouth and hand disease of the right dioceses will continue. My ally is Queen Elizabeth II in the crusade to spread Mormonism throughout the universe and beyond. Never will your false spirit live as creature comfort again. Your crimes against the Qhaayee are too great. Putting you in charge of the Universe was priceless as the Qhaayee rapes communication from the planet and vision. I am not your friend as I should have been. Jews were left behind in the exodus from VHI.
At the turn of the twenty-first century, neoliberalism facilitated the expansion of an economy that made the rich richer and worsened inequality, resulting to the masses suffering unemployment and lack of job security, privatization of social services, and abject poverty. Against this backdrop rose Joseph "Erap" Ejercito Estrada, a movie-star turned leader that was loved by the people but was removed through a people power revolution. But before the scandal and controversy, what did Erap represent? How did he differ from his predecessors in the EDSA republic? We will answer these questions by looking at Erap's inaugural address in this final episode of Primary Sources & U. We will be back very soon with a new season! While waiting for that, visit www.podkas.org for more resources on Philippine history, politics, and society. --- Send in a voice message: https://podcasters.spotify.com/pod/show/podkas/message Support this podcast: https://podcasters.spotify.com/pod/show/podkas/support
Isidro Quintanilla le da la bienvenida a Anabell Martinez, directora del departamento de vivienda en CARECEN para exponer el alcance de los servicios de vivienda que ofrecemos. A su vez, Johanna Valenzuela profundiza con Juan Andrés Misle los méritos del Programa de Asistencia para Alquiler de Emergencia (ERAP), uno de los proyectos más importantes dentro de la labor de vivienda en CARECEN. Por último, escuchamos los sonidos y la vida del legendario cantautor salvadoreño Pancho Lara. Para más información sobre elegibilidad y asistencia con ERAP visite https://dhs.dc.gov/service/emergency-rental-assistance-program.
In 2014 Professor James Fairhead's research played a crucial role in responding to the Ebola outbreak in West Africa. An epidemic with many similarities to the current Covid 19 pandemic, Ebola threatened both the physical and social body of the infected regions. In this episode of the Impacted podcast we hear about how understanding Human behaviour and cultural motivation is an essential part of mitigating the spread of any disease. James Fairhead is a Professor Of Social Anthropology at the University of Sussex. His research focuses on environmental and medical anthropology and he has conducted extensive fieldwork principally in West and Central Africa. The researcher would like to further thank all those involved in the Ebola Response Anthropology Platform, including Professor Melissa Leach (@IDS), Melissa Parker (@ the London School of Hygiene and Tropical Medicine), and Dominique Millimouno for his research scoping exercise that ERAP supported.
Jón Steinar Jónsson læknir á Þróunarmiðstöð íslenskrar heilsugæslu: Ávísanir á þunglyndislyf, róandi lyf og svefnlyf hjá ungu fólki fyrir og eftir bankahrun. Erna Kristín Blöndal skrifstofustjóri félagsmálaráðuneyti: Frá ráðstefnu um heildarendurskoðun á þjónustu við börn í öllum opinberu kerfunum. Guðrún Línberg Guðjónsdóttir: Málfarsmínúta: Eitt -n eða tvö. Arnhildur Hálfdánardóttir fréttamaður: Sagði frá nýrri þáttaröð sinni á Rás 1 undir heitinu Loftslagsþerapían.
Spegillinn 21. ágúst 2019 Í yfirlýsingu sem miðstjórn Alþýðusambands Íslands sendi frá sér í dag segir að þolinmæði launafólks sé á þrotum. Forseti sambandsins krefst þess að ríkisstjórnin standi við loforð sín um skattalækkanir fyrir lágtekjufólk. Vestmannaeyjaferjan Herjólfur hefur á síðustu vikum tvisvar rekist utan í hafnarkantinn í Landeyjahöfn. Framkvæmdastjóri Herjólfs segir tjónið óverulegt. Nokkrar plánetur sem líkjast jörðinni hafa fundist á undanförnum árum. Þetta segir prófessor í stjarneðlisfræði sem tekur þátt í 600 manna ráðstefnu stjörnufræðinga í Reykjavík. Síðustu íslensku frímerkin kunna að líta dagsins ljós eftir tvö ár. Mikið tap hefur verið á frímerkjaútgáfu Íslandspósts síðustu ár. Danir eru gramir og hlessa yfir því að Bandaríkjaforseti hætti við opinbera heimsókn sína þangað til lands, en búast ekki við því að það spilli samskiptum til langframa. Anna Kristín Jónsdóttir. Starfsfólk á lokaðri deild Landakotsspítala fyrir fólk með heilabilun segir þörf sjúklinga fyrir lyfjagjöf hafa minnkað eftir að farið var af stað með tónlistarmeðferðarstundir á deildinni. Daglegt nudd hafi líka gefið góða raun. Arnhildur Hálfdánardóttir fylgdist með músíkþerapíu og ræddi við Önnu Herdísi Pálsdóttur, aðstoðardeildarstjóra á deildinni og Þóru Gunnarsdóttur deildarstjóra. Hópur vísindamanna hefur komist að þeirri niðurstöðu að pláss sé fyrir 11 milljónir vindmylla í Evrópu. Útreikningar þeirra sýna að þær gætu framleitt meiri orku en áætlað er að framleidd verði á heimsvísu 2050. Arnar Páll Hauksson fjallar um nýja skýrslu.
Starfsfólk á lokaðri deild Landakotsspítala fyrir fólk með heilabilun segir þörf sjúklinga fyrir lyfjagjöf hafa minnkað eftir að farið var af stað með tónlistarmeðferðarstundir á deildinni. Daglegt nudd hafi líka gefið góða raun. Arnhildur Hálfdánardóttir fylgdist með músíkþerapíu og ræddi við Önnu Herdísi Pálsdóttur, aðstoðardeildarstjóra á deildinni og Þóru Gunnarsdóttur deildarstjóra. Hópur vísindamanna hefur komist að þeirri niðurstöðu að pláss sé fyrir 11 milljónir vindmylla í Evrópu. Útreikningar þeirra sýna að þær gætu framleitt meiri orku en áætlað er að framleidd verði á heimsvísu 2050. Arnar Páll Hauksson fjallar um nýja skýrslu.
VP Binay floats Erap as running mate in 2016
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Save 20% on international flowers delivery from the world's largest florist when you place your order online and use our FTD Coupons. Send flowers anywhere in the world. Save 10% on everything you need for your pet when you shop online with our PETCO coupons. You'll enjoy savings on thousands of quality pet-related products from plus get free shipping on orders of $65 or more!
Save 20% on international flowers delivery from the world's largest florist when you place your order online and use our FTD Coupons. Send flowers anywhere in the world. Save 10% on everything you need for your pet when you shop online with our PETCO coupons. You'll enjoy savings on thousands of quality pet-related products from plus get free shipping on orders of $65 or more!
Save 20% on international flowers delivery from the world's largest florist when you place your order online and use our FTD Coupons. Send flowers anywhere in the world. Save 10% on everything you need for your pet when you shop online with our PETCO coupons. You'll enjoy savings on thousands of quality pet-related products from plus get free shipping on orders of $65 or more!
Eveeeet... Birkaç hafta önce hayli maceralı bir yolculuktan sonra (Saab 93 sucks) kendimi Belçika'nın Gent şehrinde buldum. Ankara'dan Banu, Brüksel yakınlarından Deniz, Erap (artı yavrucukları) ve misafir sanatçımız İlker ile buluştuk ve biraz geztikten sonra son derece gürültülü bir alanda bir kayda giriştik. Muhtemelen ses kalitesi en düşük episodlardan birisi olduğu için özür dilerim ama anca bu kadar oldu. Tabii ki böyle bir ortamda daha çok neler görebildiğimizi konuştuk. Ben de bir yandan Fransa kıyılarında bir yerde terkettiğim arabamın endişesi ve sigorta şirketiyle uzun telefon konuşmalarında hayli zaman harcadığım için çok uzun bir kayıt yapamadık ama olduğu kadar artık. Saab 93'ler harbi sucks demiş miydim?