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Why do you crave dessert after dinner? Why are you hungry again an hour after eating? And why does weight sometimes seem to accelerate even when you're watching calories? In Episode 3 of this series on ultra-processed and hyper-palatable foods, Dr. Brendan McCarthy breaks down the biology behind cravings, hunger, and weight gain. This episode connects the dots between food engineering, blood sugar spikes, insulin, and the brain's reward system—showing why this isn't a willpower problem, but a biological response to the foods we're eating. Dr. McCarthy, Chief Medical Officer at Protea Medical Center in Tempe, Arizona, explains how modern ultra-processed foods are designed to override normal satiety signals, destabilize blood sugar, and drive continued consumption. Over time, this can create hormonal changes that make weight gain easier and weight loss harder. In this episode you'll learn: • Why ultra-processed foods trigger cravings and repeat eating • How glycemic spikes lead to hunger shortly after meals • The role of insulin as a “routing hormone” for calories • How food processing affects fat storage in the body • Why weight gain can accelerate over time • Why this is not a failure of willpower This series focuses on precision nutrition and endocrinology, helping you understand the real biological mechanisms behind metabolism, hunger, and weight regulation. If you've ever wondered why controlling food intake feels so difficult despite your best efforts, this episode will help you understand what your body is actually responding to. Citations: Episode 3 — Mechanism-Anchored Evidence Summary This episode explores how ultra-processed foods, liver metabolism, adipose tissue, hormones, and brain signaling interact to drive cravings, fat storage, and weight gain. Key mechanisms and supporting references include: Hepatic First-Pass Metabolism: Carbohydrates enter the liver via portal circulation, controlling post-meal fuel distribution (Samuel & Shulman, 2016). Fructose and Lipogenesis: Fructose bypasses key glycolytic regulation, fueling hepatic fat synthesis (Softic et al., 2020). De Novo Lipogenesis: Excess carbs activate SREBP-1c and ChREBP, producing triglycerides in the liver (Donnelly et al., 2005). VLDL Export: Hepatic triglycerides are packaged into VLDL and sent to adipose tissue (Adiels et al., 2008). Adipose Storage: Lipoprotein lipase delivers circulating triglycerides to fat cells (Kersten, 2014). Insulin Resistance: Hepatic lipid accumulation impairs insulin signaling (Samuel et al., 2004). Hyperinsulinemia & Fat Storage: Insulin promotes triglyceride storage and suppresses lipolysis (Czech, 2017). Aromatase & Estrone: Expanded adipose increases aromatase activity, raising estrone levels (Simpson et al., 1999; Key et al., 2002). Inflammation: Enlarged fat cells release cytokines, worsening insulin resistance (Hotamisligil, 2006). Ultra-Processed Foods & Overeating: Highly palatable foods drive excess calorie intake (Hall et al., 2019). Reward Signaling: Dopamine pathways reinforce eating behaviors (Volkow et al., 2013). Satiety Disruption: Low fiber and processed structure bypass satiety hormones like GLP-1 and PYY (Slavin & Green, 2007). Synthesis: Ultra-processed foods → rapid hepatic load → lipogenesis → triglyceride export → adipose expansion → estrone increase → inflammation & insulin resistance → cravings and repeated consumption. This creates a self-reinforcing metabolic cycle linking diet, liver, adipose tissue, hormones, and behavior. Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.
Le praticien Felix Kersten, par ses massages, avait le don de soulager les douleurs d'Himmler. Il en a profité pour sauver bien des vies. Plongez dans l'incroyable histoire de Felix Kersten, médecin hors du commun qui a réussi à sauver des milliers de vies durant la Seconde Guerre mondiale. Alors qu'il est appelé pour soigner Heinrich Himmler, le redoutable chef des SS, Kersten se retrouve dans une position délicate mais décide d'utiliser cette relation de confiance pour intercéder en faveur de ses nombreux amis, juifs, résistants et opposants au régime nazi.Sous la plume passionnante de Franck Ferrand, découvrez comment cet homme a réussi, malgré les dangers, à convaincre Himmler d'épargner des milliers de détenus des camps de concentration, allant jusqu'à négocier secrètement avec un représentant du Congrès juif mondial dans les derniers jours du Troisième Reich.
In this episode of Aging Well With VNA, host Kersten Rettig is joined by John W. Burruss, M.D., Psychiatrist and CEO of Metrocare, for a thoughtful and timely conversation on the powerful connection between mental health and aging well.Dr. Burruss and Kersten explore how mental and emotional health influence both chronological age and biological age, shaping how we feel, function, and thrive as we grow older. The discussion takes a closer look at the often‑overlooked mental health challenges faced by caregivers, including stress, burnout, and emotional fatigue, and how these experiences can affect long‑term health.The conversation also addresses the profound impact of grief on mental well‑being—how loss changes the brain, the body, and our sense of self, and why acknowledging and supporting mental health during grief is essential at any age.Listeners will walk away with practical, actionable advice for aging well, including strategies to support brain health, build emotional resilience, and protect mental wellness through life's transitions. This episode offers compassionate insight, medical expertise, and hopeful guidance for individuals, caregivers, and families navigating the journey of aging. Helpful resources:Metrocare: https://www.metrocareservices.org/Center for Brain Health: https://centerforbrainhealth.org/National Alliance for Caregiving: https://www.caregiving.org/
What do you do when the light refuses to cooperate? In this episode of the Camera Shake Podcast, Kersten is joined by concert photographer Steve Brazil to explore how photographers can create powerful, emotional images in the most challenging low-light conditions.Drawing on years of experience shooting live music, Steve shares how working in unpredictable and often terrible lighting environments sharpens creative instincts, forces faster decision-making, and shifts the focus from technical perfection to emotional impact. The conversation covers low light photography, anticipation, motion blur, embracing imperfection, and why bad lighting can actually make you a stronger photographer.Although rooted in concert photography, the lessons apply equally to wedding photography, street photography, documentary work, and any situation where lighting conditions are far from ideal.If you're interested in photography, videography, or building a sustainable photography business, this episode offers real-world insight you won't get from spec sheets or gear reviews.
Drohnen statt Traktoren in der Landwirtschaft - eines der Themen auf der Fruit Logistica in Berlin. Die weltweit größte Messe für den Fruchthandel zieht Kunden aus 145 Ländern an und geht noch bis Freitag. Von Jörn Kersten
Der Stromausfall in Berlin zum Jahresanfang hat die Nachfrage nach privaten Notstromaggregaten in die Höhe schnellen lassen - um im Notfall zumindest einige Geräte am Laufen zu halten. Allerdings ist beim Betrieb laut TÜV Verband Vorsicht geboten. Von Jörn Kersten
Readings for Sunday, February 8, 2026 - Fifth Sunday in Ordinary Time. Year A FIRST READING: Isa 58:7-10 Ps 112:4-5, 6-7, 8-9. "A Light rises in the darkness for the upright." SECOND READING: 1 Cor 2:1-5 GOSPEL ACCLAMATION (John 8:12). Alleluia, alleluia! I am the light of the world, says the Lord. The man who follows me will have the light of life. GOSPEL: Matt 5:13-16 The readings this weekend clearly point us to how we are to live as disciples, to be generous, merciful and just, and to share of oneself, a sharing that hurts and can be a cross to carry. But with God's grace, we can be that disciple. Salt, light, a city. +++++ References: Fr Paul W. Kelly; Kersten, J. (2013). New —St. Joseph Sunday Missal, Canadian Edition. New Jersey: Catholic Book Publishing Corp., p. 215; Link, M. (1992). Vision. Year A. Allen, Tex: Tabor Pub. Image Credit- https://creator.nightcafe.studio/creation/pS38ayOHJjscYiSqOi21?ru=Paul-Evangelion ++++++++ "Faith, Hope and Love - Christian worship and reflection" - Led by Rev Paul Kelly Prayers and chants — Roman Missal, 3rd edition, © 2010, The International Commission on English in the liturgy. (ICEL) Scriptures - New Revised Standard Version: © 1989, and 2009 by the NCC-USA. (National Council of Churches of Christ - USA) "The Psalms" ©1963, 2009, The Grail - Collins publishers. Prayers of the Faithful - " Together we pray" by Robert Borg'. E.J. Dwyer, Publishers, (1993) . (Sydney Australia). Sung "Mass In Honour of St. Ralph Sherwin" - By Jeffrey M. Ostrowski. The Gloria, Copyright © 2011 ccwatershed.org. - "Faith, Hope and Love" theme hymn - in memory of William John Kelly - Inspired by 1 Corinthians 13:1-13. Music by Paul W. Kelly. Arranged and sung, with additional lyrics by Stefan Kelk. 2019. "Quiet Time." Instrumental Reflection music. Written by Paul W Kelly. 1988, 2007. & This arrangement: Stefan Kelk, 2020. - "Today I Arise" - For Trisha J Kelly. Original words and music by Paul W. Kelly. Inspired by St Patrick's Prayer. Arranged and sung, with additional lyrics by Stefan Kelk. 2019. Sound Engineering and editing - P.W. Kelly. Microphones: - Shure MV5 Digital Condenser (USB) Editing equipment: NCH software - MixPad Multitrack Studio Recording Software NCH – WavePad Audio Editing Software. Masters Edition v 12.44 Sound Processing: iZotope RX 6 Audio Editor [Production - KER - 2026] May God bless and keep you.+++++++++++++++++++++++++++++
In Berlin sollen zwei Standorte eines Arzneimittelproduzenten schließen. Dabei wollte die Politik eigentlich die Herstellung von Medikamenten hierzulande stärken. Der Branchenverband kritisiert fehlende Unterstützung. Von Jörn Kersten und Anna Corves
Terugblik op de wedstrijd MHV 81 tegen SEW met Pien Kersten
Bram van Polen, Gertjan Verbeek, Melvin Platje en Sam Kersten zijn te gast in een speciale uitzending van De Voetbalkantine waarin geloot wordt voor de kwartfinales van de Eurojackpot KNVB Beker. De gastheren zijn Wouter Bouwman & Yordi Yamali. Heerenveen-verdediger Kersten verricht de loting. Ook bellen we met bekerheld Jari De Busser van Go Ahead Eagles en spreken we Jorrit Hendrix over zijn nominatie voor doelpunt van het jaar in Duitsland. Learn more about your ad choices. Visit podcastchoices.com/adchoices
Bram van Polen, Gertjan Verbeek, Melvin Platje en Sam Kersten zijn te gast in een speciale uitzending van De Voetbalkantine waarin geloot wordt voor de kwartfinales van de Eurojackpot KNVB Beker. De gastheren zijn Wouter Bouwman & Yordi Yamali. Heerenveen-verdediger Kersten verricht de loting. Ook bellen we met bekerheld Jari De Busser van Go Ahead Eagles en spreken we Jorrit Hendrix over zijn nominatie voor doelpunt van het jaar in Duitsland. Learn more about your ad choices. Visit podcastchoices.com/adchoices
Geisel, Sieglinde www.deutschlandfunkkultur.de, Lesart
Geisel, Sieglinde www.deutschlandfunkkultur.de, Lesart
In this episode of the Camera Shake Podcast, Kersten chats with Carl van den Boom, CEO and co-founder of Vallerret Photography Gloves, to uncover how a cold-weather frustration turned into one of the most trusted brands in outdoor photography. Carl shares the early days of sketching and prototyping, the design challenges behind making gloves specifically for photographers, and the process of growing a niche product into a global business.This conversation blends photography, creativity, and entrepreneurship—perfect for anyone looking to build a photography business, refine their craft, or simply get inspired by a founder who carved out his own lane in the industry. From business lessons to creative focus, Carl gives a refreshingly honest look at what it takes to turn an idea into a company photographers rely on.
Kersten, Paula www.deutschlandfunk.de, Das war der Tag
Neuropathic pain affects nearly 10% of the global population, yet effective treatments remain elusive. In this episode of Spark Time, we sit down with oncologists-turned-biotech-founders Christian Kersten and Marte Cameron of Akigai to hear the remarkable story of how a serendipitous clinical observation led to a new approach for treating chronic pain.From the first wheelchair-bound patient who walked again after EGFR inhibitor therapy, to the 100+ patients who have since experienced life-changing relief, Christian and Marte share the science and the vision behind Akigai's mission: to bring effective, non-opioid solutions to millions living with neuropathic pain. This is a story of discovery, persistence, and hope for one of medicine's most stubborn challenges.