Podcasts about HRT

Welcome to this week's Midlife Minute episode. We're focusing on the importance of having good mental health today. Statistics show that women are experiencing increased anxiety, depression, insomnia, and even suicidal thoughts during midlife, yet the stigma around mental health remains surprisingly strong. Join me as I explore the science behind this, why it's happening, and the importance of empowering yourself to demand better care. IN THIS EPISODE, YOU WILL LEARN: The issues that contribute to the midlife mental health challenges women are experiencing How sleep disruptions in perimenopause increase anxiety, depression, and irritability The metabolic and endocrine factors that can compound mood instability in midlife Why perimenopause is a neurological as well as reproductive transition The evidence-based benefits of HRT for supporting mental health The role of estrogen in brain function and emotional regulation Why HRT is especially important for women experiencing abrupt or early menopause Some practical guidance for using HRT to support mental health Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website. Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. Cynthia's Menopause Gut Book is on presale now! Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line References: Effects of Estradiol Withdrawal on Mood in Women With Past Perimenopausal Depression: A Randomized Clinical Trial (https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2298235)  Efficacy of Estradiol in Perimenopausal Depression: So Much Promise and So Few Answers (https://onlinelibrary.wiley.com/doi/10.1002/da.22391) Effects of Hormone Therapy on Cognition and Mood (https://www.fertstert.org/article/S0015-0282(14)00178-2/fulltext) Does Menopause Hormone Therapy Improve Symptoms of Depression? Findings From a Specialized Menopause Clinic  A Meta-analysis of the Effect of Hormone Replacement Therapy upon Depressed Mood (https://www.sciencedirect.com/science/article/abs/pii/S0306453096000340?via%3Dihub) The Effect of Hormone Replacement Therapy on Cognition and Mood (https://onlinelibrary.wiley.com/doi/10.1111/cen.14856)

FREE SUPPORT & RESOURCES:‣ Book a COMPLEMENTARY CONSULTATION + CALORIE CALCULATION call• how much & what to eat

Reclaim Your Vitality: Science-Backed Detoxification with Dr. Haroldo Magarinos What if your fatigue, inflammation, hormone resistance, brain fog, or "detox reactions" aren't because you need more supplements—but because your body can't clear what it's already carrying? In this episode of The Coach Debbie Potts Show, I'm joined by Dr. Haroldo Magarinos, founder of Reclaim Your Vitality, for a grounded, science-backed conversation on what detoxification actually means—and why so many high performers get it wrong. We unpack the missing physiology behind detox programs, hormone optimization, and "biohacking," especially for driven midlife athletes and professionals who are doing all the right things but still feel stuck. This is not about aggressive cleanses or pushing harder. It's about capacity, flow, and order of operations. In this episode, we explore: • Why detox is a biological process, not a product or protocol • How the nervous system, liver, bile, gut, kidneys, and lymph must work together • Why poor bile flow leads to hormone recirculation, histamine overload, and inflammation • The connection between chronic stress, mitochondrial energy, and impaired detox pathways • Why many people feel worse during detox—and how to prevent that • How to rebuild drainage, resilience, and metabolic harmony before adding HRT, peptides, GLP-1s, or intense training • What "science-backed detox" actually looks like in real life Dr. Magarinos brings clarity to the confusion around detoxification by anchoring the conversation in physiology, systems biology, and clinical experience—cutting through fear-based marketing and outdated models. If you've ever said: "I've tried detoxing, but it didn't work." "I react to everything." "My labs look okay, but I don't feel okay." "Hormones and supplements aren't helping." This episode will help you understand why—and what needs to come first. Because real vitality isn't forced. It's restored—by improving flow from the inside out.

Adele is joined by Dr Salas-Whalen to explore the evolving role of GLP-1 medications in perimenopause and menopause care. Moving far beyond outdated BMI measures and “skinny jab” stereotypes, they unpack body recomposition, metabolic health, strength training and protein intake, and ask whether GLP-1 therapy and HRT could one day work hand in hand to support women's long-term health, cognition and cardiovascular wellbeing. This is a nuanced, empowering discussion designed to help you make informed, evidence-based decisions about your midlife health. Follow Dr Salas-Whalen's Insta: https://www.instagram.com/drsalaswhalen/ Official site for Weightless the Book: https://weightlessthebook.com/ Dr Salas-Whalen's StrengthMD brand:  https://strengthmd.co/   ____________ Check out Adele's FREE symptom assessment here: https://adelejohnstoncoaching.com/free-copy-of-our-symptom-assessment/ 12 Minute Breathwork Method: https://adelejohnstoncoaching.com/breathwork/ The Menopause Cheat Sheet: https://docs.google.com/document/d/1ka-fN6J5DJW2J3IE0Qa80zFCKFXmTs4srlnlXYBf-gA/edit?usp=sharing If you want a chat for your future success, fuel yourself here: https://calendly.com/adelejohnston/successchat Download Adele's Journey Journal here : https://adelejohnstoncoaching.com/my-journey-journal/ Enquire about 121 coaching here : https://docs.google.com/forms/d/e/1FAIpQLSfw6vrmKPE7A1eYDKQJiR9No7ZDdpfq-grBdKYjZSR-vl0Qag/viewform For extra support: Support@adelejohnstoncoaching.com ____________ From your host : Adele Johnston I'm Adele Johnston, a certified nutritionist and positive psychology coach, passionate about helping women improve their menopause health and reclaim who you are without menopause taking over. This is a time in your life where you get to feel vibrant, sexy and reclaim you again! I'm proud to work with women like you and have created a very successful proven Reclaiming You 3 STEP PROCESS to help you take back control of your body during your menopause. For more details : https://adelejohnstoncoaching.com/ To get Adele's FREE 3-step Menopause Weight Loss Guide: https://adelejohnstoncoaching.com/menopause-weight-loss-guide/

Most symptoms we're dealing with as active women and runners aren't random at all, but are instead clues our body is trying to give us.In this episode, Louise, a multi-award-winning women's integrative health practitioner, shares three powerful lessons from her own health journey and client experiences that every woman should know, especially during perimenopause. She explains how hormone shifts can impact everything from medical testing accuracy to inflammation, fat loss resistance, stress sensitivity, and even unexpected symptoms like canker sores. One key insight is the importance of timing medical screenings, such as breast MRIs, with your menstrual cycle to improve accuracy. Another is the complex relationship between estrogen, histamine, and hormone replacement therapy, and how individual genetics can influence reactions.Louise also highlights how stress, calorie restriction, and hormonal fluctuations can trigger symptoms that seem unrelated, and offers practical strategies to manage acute issues while still addressing root causes like gut health and hormone balance.This episode is a reminder that women's health is highly individualized. Understanding your unique physiology, tracking patterns, and using targeted strategies can help you feel more in control, improve performance, and support long-term health through every stage of life.Explore my "All About Gut Health" and other masterclasses here: https://www.breakingthroughwellness.com/store Link to my FullScript where you can see curated best supplement picks and save 20%: https://us.fullscript.com/welcome/breakingthroughwellness/store-start Learn and level up with my free nutrition guide and award-winning Badass Breakthrough Academy to thrive through perimenopause with less stress: https://www.breakingthroughwellness.com/Take advantage of our podcast listener discount and save 20% off all of Kion's science-backed clean products. Code "LOUISE" saves on all future orders: : https://www.getkion.com/pages/maximizing Episode Highlights:(0:00) Intro(3:05) Three important women's health lessons(6:15) Missed eligibility for early breast screening(9:46) Hormones affecting MRI and mammogram accuracy(13:09) Best timing for breast imaging in cycle(15:10) Hormone optimization and HRT considerations(19:01) Estrogen patch reaction case study(21:58) Estrogen, histamine, and mast cell connection(27:14) Managing histamine overload and recovery(35:24) Stress sensitivity during perimenopause explained(40:00) Hormones, stress, and canker sore triggers(42:49) Gut health and autoimmune connections(46:39) L-lysine for acute outbreak management(51:08) Symptom relief vs root cause approach(52:19) Upcoming resources and listener updates(54:15) OutroTune in weekly to "Maximizing Hormones, Physique, and Running Through Perimenopause" for our simple female-specific science-based revolution. Let's unlock our best with less stress!I'd love to connect! Email

In this episode, I sit down with neuroscientist Dr. Louisa Nicola to unpack what women actually need to know about Alzheimer's risk, cognitive decline, and long term brain protection. We break down APOE genetics, advanced blood biomarkers that can now detect amyloid and tau with remarkable accuracy, and why brain health is inseparable from metabolic health. Louisa explains how muscle acts as a metabolic sink for glucose, why resistance training and high intensity intervals stimulate BDNF, and how sleep drives the glymphatic system to clear amyloid from the brain. If you want practical tools to assess your personal risk, understand your labs, and build a proactive prevention plan decades before symptoms appear, this conversation is for you. → Leave Us A Voice Message!  Topics Discussed: → What does APOE4 mean for Alzheimer's risk? → Can exercise prevent cognitive decline? → Do blood tests detect early Alzheimer's? → How does perimenopause affect brain health? → Does hormone therapy reduce dementia risk? Sponsored By:  → Timeline | Support your cells and how you age with Mitopure® Gummies from Timeline. Visit https://timeline.com/KELLY and save up to 39% off your Mitopure® Gummies. → Be Well By Kelly Protein Powder & Essentials | Get $10 off your order with PODCAST10 at https://bewellbykelly.com. → Cozy Earth |  Head to https://cozyearth.com and use code BEWELL for up to 20% off. And if you get a post-purchase survey, make sure you tell them you heard about Cozy Earth right here at the Be Well by Kelly podcast.  → LMNT | Get a free 8-count Sample Pack of LMNT's most popular drink mix flavors with any purchase at https://drinklmnt.com/Kelly. Find your favorite LMNT flavor, or share with a friend. Timestamps:  → 00:00:00 - Introduction → 00:01:27 - Mission to end Alzheimer's  → 00:03:28 - Women's rate of Alzheimer's  → 00:04:11 - Alzheimer's overview  → 00:07:44 - Education level & health  → 00:09:57 - Anatomy  → 00:14:16 - Neuroplasticity & glucose  → 00:19:38 - Amyloid-beta → 00:26:41 - LDL Cholesterol → 00:28:36 - Preparing for menopause  → 00:31:30 - Blood testing recommendations  → 00:34:26 - Lifestyle interventions  → 00:39:05 - Nutrition & the MIND diet  → 00:42:19 - Zone 2 vs zone 5 training  → 00:44:36 - Lactic acid  → 00:47:58 - HRT is protective → 00:50:19 - When to test for HRT → 00:51:56 - Testosterone + brain health  → 00:53:40 - Cognitive reserve  → 00:57:12 - Hot flashes  → 00:58:13 - Quick fixes  → 01:00:01 - Brain surgery  → 01:05:38 - The brain code  Show Links: → Function | Own your health for $365 a year. That's a dollar a day. Learn more and join using my link. Visit https://www.functionhealth.com/bewellbykelly and use gift code BEWELL25 for a $25 credit toward your membership Further Listening: → How to Take Control of Your Health in a Toxic Food Landscape | Max Lugavere  Check Out Louisa:  → Instagram  → The Brain Code Check Out Kelly: → Instagram → Youtube → Facebook

Are you dreading menopause? What if the menopause horror stories you've heard aren't the whole truth? Women across five continents have shared surprisingly different experiences with this inevitable life transition, and their insights might completely change how you approach your own future health.Jenn Trepeck hosts returning guest Zora Benhamou on Salad with a Side of Fries for a groundbreaking conversation about menopause around the world. As a gerontologist who's interviewed over 300 women from Vietnam to France, Zora reveals which symptoms appear universal, which treatments different cultures embrace, and why almost no one's mother prepared them for this transition, regardless of where they live.What You Will Learn in This Episode:✅ How socioeconomic status and stress management impact the timing and severity of menopause symptoms across different cultures and communities worldwide.✅ Why menopause experiences with hormone replacement therapy vary dramatically from Spain's hesitation to France's acceptance, and what this reveals about menopause stigma.✅ The surprising universality of hot flashes and mood swings despite geographic differences, plus which Asian countries show remarkable openness about libido changes during the perimenopause transition.✅ How gerontology research connects the mind-body connection to aging gracefully, and why understanding your entire life course health matters for longevity planning.The Salad With a Side of Fries podcast, hosted by Jenn Trepeck, explores real-life wellness and weight-loss topics, debunking myths, misinformation, and flawed science surrounding nutrition and the food industry. Let's dive into wellness and weight loss for real life, including drinking, eating out, and skipping the grocery store.TIMESTAMPS: 00:00 Global menopause perspectives and how cultural menopause experiences shape women's transitions worldwide05:59 Understanding gerontology research and why the mind-body connection matters from birth through post menopause life08:59 Gathering research from over 300 women about menopause, asking five questions16:21 Socioeconomic status impact on perimenopause transition timing and how stress management affects menopause anxiety levels20:54 Hot flashes: universality versus cultural differences in libido changes and mood swings during hormonal transitions23:08 Hormone replacement therapy attitudes and HRT options 27:19 Understanding menopause as a spectrum with diverse experiences and tools to make the perimenopause transition easier29:02 Breaking menopause stigma through conversation and recognizing menopausal depression as life-threatening, and why knowing it's hormones, not you, can save lives30:47 Cultural differences in menopause discussion from the Czech Republic's ageism to varying levels of openness worldwide33:21 How household support and reverence for older women create better menopause outcomes and easier transitions36:18 Understanding perimenopause starts in mid-thirties with progesterone loss, not just something after age 5038:40 The 103 menopause symptoms beyond hot flashes, including joint pain, anxiety, and sleep issues, are often misdiagnosed39:43 Testing, measuring, and assessing perimenopause symptoms through data tracking and biohacking for better healthKEY TAKEAWAYS:

Perimenopause and Menopause Myths Busted! Welcome back to the Menopause Mastery Podcast! In this eye-opening episode, Dr. Betty Murray and guest Kelly Resendez get real about the top myths and truths that surround perimenopause, menopause, and post-menopause—especially when it comes to hormone replacement therapy. From the difference between bioidentical and synthetic hormones to the controversies sparked by past research, they break down the complexities in simple, relatable terms. Dr. Betty Murray shares the latest science on what actually keeps women healthy as they age, including the impact of hormones on long-term health, bone density, brain function, and more. Plus, they tackle the confusion around lab ranges, hormone metabolism, and the power of having individualized care. Whether you're navigating these changes yourself or supporting someone who is, this episode will empower you with the knowledge, the facts, and the hope you need to take control of your hormonal health—without judgment or misinformation. Let's set the record straight and help you thrive during every stage of your menopause journey! Chapters: 00:00 "Bioidentical vs Synthetic Hormones" 03:23 Synthetic vs. Bioidentical Hormones 06:34 Menopause Hormone Therapy Controversy 11:13 "Hormones: The Body's Cleanup Crew" 13:15 Patient Story: Hormone Therapy Oversights 18:45 "Testosterone and Women's Health" 19:46 "Empowering Women Through Hormone Care" 23:47 "Menopause Mastery: Real Solutions"   Quick Takeaways: Start the HRT conversation early—within 10 years of menopause is optimal for the best long-term benefit. Bioidentical HRT is individualized: what works for your best friend isn't automatically right for you. Testing matters: Only using symptoms to judge your treatment might leave you unprotected; get those numbers checked! Don't let someone else's bad experience steer you away—your journey is unique, and doses can be tailored just for you. If you're ready to stop guessing and want a plan that's tailored to you, check out gethormonesnow.com. We're here to guide you through every step. Let's make this your most empowered chapter yet.  

In Part 1, I shared how my own bloodwork forced me to question everything I thought I knew about cholesterol. In this episode, we go deeper — into the markers that actually predict cardiovascular risk and why so many women are being reassured by tests that don't tell the full story. Because a "normal" cholesterol panel doesn't mean your risk is low. It often just means the most important markers were never measured. I walk you through the two advanced markers that can completely change how we understand heart disease risk — especially when genetics are involved — and why these tests are essential if you want a clear, accurate picture of your cardiovascular health. We also have an honest conversation about cholesterol-lowering medications: what they do, when they make sense, and why modern medicine can be protective when used thoughtfully and strategically. This isn't about fear. It's about clarity. It's about having the full picture so you can make informed decisions about your health and your future.   In this episode of The Perimenopause Solution Podcast, you'll learn: • Why a standard cholesterol panel often misses true cardiovascular risk • What Lipoprotein(a) is and why genetics play a major role • Why ApoB is one of the strongest predictors of heart disease • How advanced markers change risk assessment — even when traditional labs look "normal" • The truth about cholesterol-lowering medications and how they work in the body • When lifestyle is enough — and when additional support may be protective • How to advocate for the testing and information you deserve If you've ever been told your cholesterol looks "fine," this episode will help you understand what may still be missing — and why that matters. WATCH ON YOUTUBE ------------------------------------------- HANGOUT WITH TARA ON FEBRUARY 24TH My Perimenopause Hangout is happening on February 24th and there's still time to join HERE. This isn't a fluffy webinar. It's a no-BS sit-down chat where I'll hand you a real-life roadmap for navigating midlife hormones + metabolism, so you finally know what to focus on (and what to stop wasting money on). You'll leave with strategies you can use the very next day. No starving yourself, no supplement graveyard. Show up live and you'll also get my best bonuses that only my clients typically get: Ultimate Midlife Blood Work Guide: The Tests Your Doctor Skips + Ranges That Actually Mean Something, (Not Just "You're Alive") Hormone Decoder Cheat Sheet: How To Talk To Your Doctor About the Right Hormones, Right Doses, Right Delivery, Even If Round 1 Failed Protein Made Simple Cheat Sheet: Help Figuring Out Your Daily Target + Meal Ideas & Easy Ways To Hit Your Protein Goals. The Magnesium Decoder Cheat Sheet: Which Form Does What + Electrolytes I Recommend. ​Save your free spot here!   Mentioned in this episode: HERBATONIN - Save 10% when you shop HERE and use Tara's code: Tara10       EQUIP - Click HERE to grab yours and use Tara's code: TARA to get 15% off When you sign up for a subscription via Tara's link, you'll save 30% on the first month & 15% on any subsequent months!        PIQUE TEA - These are some of Tara's favourite teas! They're crystal form, which makes them super unique and easy to transport in your purse, (they come in single use satchels!) and higher in polyphenols. They're made from high quality ingredients with triple toxin screening, (super important when it comes to your tea). Click HERE to visit the shop.           HRT Made Simple™ - Learn how to confidently speak to your doctor about the benefits of hormone replacement therapy so you can set yourself up for symptom-free, unmedicated years to come without feeling confused, dismissed, or leaving the medical office minus your HRT script. Hair Loss Solutions Made Simple™ – This course will teach you the best natural, highly effective, and safe solutions for your hair loss so you can stop it, reverse it, and regrow healthy hair without turning to medications. The Perimenopause Solution™ – My signature 6-month comprehensive hormonal health program for women in midlife who want to get solid answers to their hormonal health issues once and for all so they can kick the weight gain, moodiness, gut problems, skin issues, period problems, fatigue, overwhelm, insomnia, hair/eyebrow loss, and other symptoms in order to get back to the woman they once were. [FREE] The Ultimate Midlife Perimenopause Handbook - Grab my free guide and RECLAIM your confidence, your mood, your waistline and energy without turning to medications or restrictive diets (or spending a fortune on testing you don't need!).   [BOOK A 30-MINUTE SESSION WITH TARA HERE]  

Send Vanessa a Text MessageSpecial Offer for Listeners: Use code PODCASTDRSARAH for $50 off at Inner BalanceSupport the Intentionally Well PodcastAre hormones really the root driver of so many of the challenges women face, from brain fog and fatigue to anxiety, sleep issues, libido changes, and gut struggles? And is hormone replacement therapy, or HRT, something every woman should consider, or something to fear? In this episode, I sit down with Dr. Sarah Daccarett, MD, founder of Inner Balance and a nationally recognized expert in women's hormone health, longevity, and bioidentical hormone optimization. We dive into why she has seen so many women are chase all the wrong solutions for their health, like gut protocols, weight loss, supplements, etc., when hormones may actually be the main driver. We dive into why many women start HRT later than they might need to, and what earlier support could look like. Along the way, we unpack common misconceptions about HRT and natural aging, and explore how timing, dosage, and delivery systems can make all the difference. We also look at the broader picture of how hormones influence immunity, metabolism, sexual health, and brain function, and why fear and misinformation around HRT continue to persist.I share my own questions, hesitations, and devil's advocate thoughts throughout the conversation, and reflect on how this discussion has somewhat shifted my perspective. This is a nuanced and practical conversation for women of all ages who want to understand their bodies more deeply, make informed choices, and reclaim clarity and agency in their health.Whether you are curious, cautious, or already on your HRT journey, this episode will give you perspective, tools, and insight, with no hype, no fear, and just real information. Connect with Dr. Sarah and Inner Balance:$50 off for listeners:  Inner BalanceInner Balance on Instagram: @innerbalancemdDr. Sarah Daccarett on Instagram: @sarahdaccarettmdConnect with the Podcast:Website: Intentionally Well PodcastPodcast on InstagramVanessa on InstagramPodcast on YouTubePodcast on TikTokPodcast on XEmail: intentionallywellpodcast@gmail.com Support the showThis episode is for informational purposes only. Please consult a trusted health practitioner for individual concerns.

In this final episode of the Progesterone Promise series, Dr. Brendan McCarthy, Chief Medical Officer of Protea Medical Center, breaks down one of the most misunderstood hormones in women's health: progesterone. Progesterone is not “good” or “bad.” It's contextual. In today's world of quick sound bites and social media medicine, hormones are often reduced to oversimplified claims like “progesterone fixes anxiety” or “progesterone causes breast cancer.” The truth? It depends on your body, your stress levels, your liver health, your inflammation, your delivery method, and whether you're using bioidentical progesterone or synthetic progestins.   Citations: 1. Oral Progesterone → First-Pass Metabolism & Allopregnanolone Claim: Oral micronized progesterone undergoes significant hepatic first-pass metabolism, increasing neuroactive metabolites (especially allopregnanolone), which positively modulate GABA-A receptors and produce sedative/anxiolytic effects. Core Evidence: Simon et al., 1993; de Lignières et al., 1995; Freeman et al., 1990 — Oral progesterone produces measurable neuroactive metabolites. Paul & Purdy, 1992; Rupprecht et al., 2001 — Allopregnanolone enhances GABA-A receptor activity. Supports: Sedation variability by route • Neurosteroid generation • GABA-A modulation 2. Sulfation vs 5α-Reduction → Opposing Neurologic Effects Claim: Progesterone metabolites can produce calming (5α-reduced) or excitatory (sulfated) neurologic effects depending on enzyme routing. Core Evidence: Majewska et al., 1990 — Pregnenolone sulfate negatively modulates GABA-A. Wu et al., 1991 — Sulfated neurosteroids enhance NMDA signaling. Schumacher et al., 2007; Reddy, 2010 — Pathway reviews of sulfation vs 5α-reduction. Supports: Reverse responding hypothesis • Divergent neurologic experiences • Enzyme-dependent effects 3. Stress & Enzyme Modulation Claim: Chronic stress alters HPA axis tone and hepatic enzyme expression, influencing steroid metabolism balance. Core Evidence: McEwen, 1998 — Allostatic load model. Charmandari et al., 2005 — Cortisol's systemic regulatory effects. Zanger & Schwab, 2013; Gibson & Skett, 2001 — Stress alters cytochrome P450 expression. Supports: Stress-biased metabolism • Context-dependent hormone response 4. Breast Tissue Signaling & Context Claim: Progesterone influences mammary differentiation and interacts with estrogen signaling in context-dependent ways. Core Evidence: Brisken & O'Malley, 2010 — Progesterone receptor biology in breast tissue. Beleut et al., 2010 — RANKL mediates progesterone-driven proliferation. Hofseth et al., 1999 — PR-ER signaling interaction. Stanczyk & Bhavnani, 2014 — Natural vs synthetic differences in breast effects. Supports: Lobuloalveolar differentiation • RANKL pathway • Context-dependent proliferation 5. Synthetic Progestins vs Bioidentical Progesterone Claim: Synthetic progestins differ structurally and bind off-target receptors, producing distinct tissue effects. Core Evidence: Stanczyk et al., 2013 — Receptor binding differences. Sitruk-Ware, 2004 — Biologic comparisons. Chlebowski et al., 2003 (WHI) — Breast cancer signal with CEE + MPA. Supports: Structural divergence • Receptor-level differences • WHI clarification 6. Route of Delivery Differences Claim: Oral, vaginal, transdermal, and sublingual progesterone produce distinct pharmacokinetic profiles and tissue targeting. Core Evidence: Simon, 1995 — Oral vs vaginal PK comparison. Cicinelli et al., 2000 — “First uterine pass effect.” Wren et al., 2003 — Route-dependent systemic levels. Supports: Uterine targeting • Neurosteroid variability • Sedation differences 7. Progesterone, PMS & Migraine Claim: Neurosteroid fluctuations influence GABAergic tone and may contribute to PMS and migraine susceptibility. Core Evidence: Backstrom et al., 2011 — Allopregnanolone fluctuations in PMS. Reddy & Rogawski, 2002 — Neurosteroids and seizure threshold. Martin & Behbehani, 2001 — Hormonal fluctuations and migraine. Supports: Luteal neurosteroid shifts • GABA instability • Migraine association   Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.  

You're eating well, working out consistently, but the scale keeps climbing. Your body feels different. Your clothes don't fit. And you're wondering—am I doing something wrong, or is this just perimenopause? In this episode, I'm sitting down with Monica McKitterick, Family Nurse Practitioner and founder of Impact Family Wellness, to talk about the real reasons hormonal weight gain happens in midlife—and what you can actually do about it. We're covering HRT (the risks and benefits your doctor might not be telling you), GLP-1 medications for weight loss, thyroid issues that often get missed, and the truth about perimenopause and menopause weight gain. This is an honest, no-fluff conversation about what's happening in your body and the tools available to help. If you're frustrated, confused, or just want straight answers about hormones and weight loss, this episode is for you.   Website: www.impactfamilywellness.com www.dpcformula.com Facebook: https://www.facebook.com/impactfamilywellness/ Instagram: https://www.instagram.com/impactfamilywellness/ YouTube: www.youtube.com/@impactfamilywellnessllc4726 LinkedIn: https://www.linkedin.com/in/monicamckitterick/ https://www.linkedin.com/company/dpc-formula/  

This episode is a masterclass in both men and women's hormonal health. These hormones in effect are the clocks of aging, so much so that biotech labs can now take a few data points, consult with AI and provide you with an almost exact time until major hormonal events like menopause. Which is crucially important because to optimize health and longevity the right type of hormonal support and treatment should be started years before that. This episode is for anyone wanting to understand how hormones are the backbone of overall health, aging slower, maintaining sexual function and looking younger for longer.Dr. Amy Killen, MD received her Bachelor's degree in Biomedical science from Texas A&M University and then her MD from UT Southwestern Medical School. She completed an Emergency Medicine residency at the University of Arizona. She worked for many years in Austin, Texas as a board-certified emergency physician before moving to Portland and becoming the medical director of an anti-aging specialty clinic. Now in Utah, Dr. Killen embraces bio-identical hormone therapy and personalized medicine and offers aesthetics services, including Botox, Fillers, and Microneedling. Dr. Killen is also enthusiastic about cutting-edge rejuvenating medicine techniques, using Platelet Rich Plasma Natural Growth Factor Injections for skin rejuvenation, hair restoration, urinary incontinence, and sexual dysfunction.Contact:Website - https://dramykillen.comInstagram - @dr.amybkillen Join us as we explore:Hormone optimization, TRT and infertility, estrogen dominance in BOTH men and women and hormone enhancing (or not) peptides.Estrogen vs estrone vs estriol vs estradiol.Sexual health, ovarian aging, HRT, perimenopause and the ability of AI to predict your age of menopause onset.Why men would supplement with progesterone.  Why everyone should get a DEXA scan.Sleep optimization, skin optimization, birth control, Bryan Johnson and other biohacking insights.MentionBiotech - TimeLessBiotech, https://timelessbiotech.comBiotech - LifeAhead, https://lifeahead.coSupport the showFollow Steve's socials: Instagram | LinkedIn | YouTube | Facebook | Twitter | TikTokSupport the show on Patreon:As much as we love doing it, there are costs involved and any contribution will allow us to keep going and keep finding the best guests in the world to share their health expertise with you. I'd be grateful and feel so blessed by your support: https://www.patreon.com/MadeToThriveShowSend me a WhatsApp to +27 64 871 0308. Disclaimer: Please see the link for our disclaimer policy for all of our content: https://madetothrive.co.za/terms-and-conditions-and-privacy-policy/

Hormones can feel confusing, especially after 35 when things start to shift. In this Q&A episode, we're answering your most common hormone questions, including DIM for estrogen dominance, ovulation breakouts, and the surprising roles estrogen, progesterone, and histamine play in perimenopause symptoms. Let's make it make sense!Timestamps:[1:41] Welcome[17:18] Does taking dim for estrogen dominance help or hinder?[33:39] Are you on HRT or planning on it?[37:16] Why do I break out around ovulation always, but not around my period?Episode Links:Article: Good Culture sells majority stake Good Culture Instagram Post Episode 556: MCAS, Histamine, and POTS: The Latest Research and Root Causes with Michelle Shapiro, RD. Sponsors:Go to boncharge.com/WELLFED and use coupon code WELLFED to save 15% off any order.Go to getkion.com/wellfed to get 20% off your order. Go to http://mdlogichealth.com/wfcolostrum , and use coupon code WFC15 for 15% off. You can also use code WELLFED for 10% off site wide on all MD Logic Products. Go to wellminerals.us/vitaminc and use code WELLFED to get 10% off your order.

Struggling with weight gain, hormone imbalances, and constipation? These aren't separate issues—they're all connected, and they all start in your gut. In this episode, I'm breaking down the relationship between gut health, hormones, and weight loss that most doctors won't tell you about.You'll learn why constipation causes estrogen to recirculate in your body, how backed-up toxins slow your metabolism, the gut-thyroid connection, and why "eat more fiber" actually makes things worse when you have gut dysbiosis.If you're ready to stop micromanaging your hormones and start addressing the root cause, this episode is for you.What You'll Learn in This EpisodeWhy adding HRT on top of poor gut health is like pouring water into an overflowing bathtubWhy backed-up toxins slow your metabolism and make weight loss nearly impossibleWhat constipation actually is (hint: it's not just going less than once every 3 days)Why adding more fiber makes bloating and constipation worse if you have dysbiosisHow healing your gut naturally balances hormones and supports weight loss—without dietingTracy's story: how she stopped HRT, healed her gut, and lost two pant sizes in 12 weeksKey Takeaways[04:37] Tracy's StoryMy client Tracy came to me frustrated after starting HRT (testosterone pellet) and feeling worse—not sleeping, bloated, gaining weight, and reacting to all foods. Her GI-MAP revealed SIBO, low digestive enzymes, and poor hormone detoxification. Once we healed her gut, she didn't need to go back on HRT. Her energy returned, bloating disappeared, sleep improved, and she lost over two pant sizes without counting calories.[15:15] How the Estrobolome Works[17:42] Constipation = Estrogen Recirculation[19:47] The Gut-Thyroid Connection[22:08] Backed-Up Toxins Slow Metabolism[13:15] What Constipation Actually Is[14:15] Why "Eat More Fiber" Doesn't Work[29:45] What to Do InsteadYou don't need to micromanage hormones, count calories, or obsess over macros. You need to:Test your gut to see what's actually going onCreate a custom protocol based on your specific resultsSupport digestion with the right nutrients and targeted supplementsNourish your body with anti-inflammatory foods and blood sugar stabilityFeatured Offer: Complete Gut Healing ProgramAvailable through February 28, 2025Includes:GI-MAP at-home stool test with prepaid shippingPDF of your lab results (yours to keep)Personalized video interpretation from MelissaCustom 12-week healing protocol21-Day Gut Reset3 follow-up visits to track progress and adjust protocolInvestment: $899 (payment plans available, HSA/FSA accepted)Expected Results in 12 Weeks:Significantly decreased bloatingRegular daily bowel movementsDecreased or zero food sensitivitiesClearer skinEasier, less painful periodsMental clarity and more energyNatural weight loss without dietingHow to Sign Up:Link in show noteLink in Instagram bio: @melissa_eichDM "GUT" on InstagramEmail: melissa@mindfullywell.comResources MentionedPrevious Episode: "Why Your Gut is Ground Zero for Healing in Midlife" Click here to listen: https://podcasts.apple.com/us/podcast/165-gut-health-in-perimenopause-why-healing-your-gut/id1650475536?i=1000749067193GI-MAP Functional Stool TestDUTCH Test (Dried Urine Test for Comprehensive Hormones)Instagram: @melissa_eichEmail: melissa@mindfullywell.com

In this milestone 100th episode of the Science of Skin podcast, Dr. Ted Lain and Dr. Patti Farris reflect on their journey, discussing impactful studies in dermatology, the importance of skincare for menopause, the definition of skin quality, and the integration of Eastern and Western medicine. They also explore the gut-skin connection, the issue of human trafficking in dermatology, and highlight pioneers in the field. The episode concludes with insights into the business of skincare and a heartfelt thank you to their loyal listeners. Takeaways This is episode number 100 for the science of skin podcast.We have a very loyal following.The antioxidant study debunked previous misconceptions.C.E. Ferulic remains foundational in skincare.The sandwich technique affects retinoid efficacy.HRT is crucial for managing menopause symptoms.Skin quality metrics are essential for patient satisfaction.Integrating Eastern medicine can enhance treatment outcomes.The gut-skin connection is scientifically supported.Human trafficking awareness is vital for dermatologists. DISCLAIMER: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment.See omnystudio.com/listener for privacy information.

What if the mood swings, the sleepless nights, the sudden irritation, and the loss of joy aren't signs that something is wrong with you…but signals that your biology is quietly staging a dramatic takeover? Kate Mason sits down with Dr. Joanna Bruce, GP of over 25 years, clinical director of Myma Health, and passionate advocate for women's hormonal wellbeing, to talk openly about perimenopause and menopause. Together they unpack why this decade-long hormonal shift is so often missed, dismissed, or misdiagnosed, and what women (and the people who love them) can actually do about it. From understanding the science of estrogen and progesterone fluctuation to debunking the damaging 2002 WHI study on HRT, this empowering conversation gives parents and partners the insight they need to understand what's really going on… in their bodies, their relationships, and their homes. Listen For2:00 What does the history of menopause research tell us about why women have been so underserved?8:20 How do you distinguish perimenopause symptoms from everyday exhaustion and stress?11:00 What are the early signs of perimenopause that women most commonly overlook?16:55 Is HRT actually safe, and why has the fear around it lasted more than two decades?25:10 What practical steps should women take if they think they are entering perimenopause? Leave a rating/review for this podcastwith one click  Connect with guest: Dr Joanna Bruce, GP & Clinical Director, Myma HealthWebsite | LinkedIn | Instagram Contact Kate:Email | Website | Kate's Book on Amazon | LinkedIn | Facebook | X

2月15日にオーストラリア・バサーストのマウント・パノラマで行われたIGTCインターコンチネンタルGTチャレンジ第1戦『マグアイアーズ・バサースト12時間』レースで、決勝序盤にカンガルーと衝突したHRT（ハウプト・レー […]

From blue light blocking glasses to hydrogen water for your mitochondria, Liz shares the science-backed strategies that protect your circadian rhythm and support healthy ageing.In this episode:Is hydrogen water worth it – and are there budget options? Which supplements should we prioritise in midlife? Do blue light blocking glasses protect your sleep?How to fix hormonal breakouts after coming off the pillCan you start HRT while you're still breastfeeding at 49?How to soothe midlife bloatingLinks mentioned in the episode:Echo hydrogen water flaskHydrogen water tabletsDr Nicholas Perricone episode on collagen and hydrogen waterLiz's favourite gut health boostersDr Uma Naidoo episode on nutrition for better mental healthOcushield blue light blocking glassesOcushield screen protectorBy Sarah Ally Recovery Blemish Facial Oil – use code LIZLOVES for 20% offBalance menopause appGet in touch with a question for Liz:Email: podcast@lizearlewellbeing.comWhatsApp: 07518 471 846More from Liz:Preorder Liz's NEW book – How to AgeA Better Second Half Follow Liz on InstagramFollow Liz Earle Wellbeing on InstagramSome links may be affiliate links, which help support the show at no extra cost to you. Read our Affiliate Policy for more information. Hosted on Acast. See acast.com/privacy for more information.

Feeling overwhelmed by conflicting advice about menopause and HRT? You're not alone, and you're not imagining it.In this eye-opening conversation, journalist and author Fiona Clark (MenoWars: Why Menopause's Moment Has Gone Horribly Wrong) joins me to unpack why the menopause conversation has become so polarizing. What started as a grassroots movement of women advocating for better care has evolved into a confusing battlefield of conflicting claims, FOMO-inducing headlines, and monetized advice that leaves women more overwhelmed than empowered.Fiona brings her unique background, which includes a degree in anatomy and physiology, decades as a journalist, and her own experience navigating menopause to help us understand how we got here. We explore the "menopause wars," from the rise of influential voices making claims that science doesn't always support, to the gatekeeping accusations that emerge when medical professionals push back, to the dangerous erosion of trust in evidence-based medicine.In this episode, we talk about:How the menopause advocacy movement transformed from collegial to combativeWhy testosterone has become the latest battleground (and what happened when Fiona stopped taking it)The FOMO epidemic: dementia, heart disease, and what the research actually showsWhy "gatekeeping" accusations undermine the scientific processThe commercialization of menopause and how confusion gets monetizedWhat HRT can (and can't) do, and why cutting out the noise matters more than anythingWhy women deserve to make informed decisions about their bodies without everyone else's opinionsFiona's message is clear: it's not about being pro- or anti-HRT. It's about cutting through the noise, understanding what science actually supports, and reclaiming your right to make informed decisions about your own body without FOMO, fear, or unsolicited opinions.If you've felt confused, frustrated, or exhausted by the menopause information overload, this conversation will help you find your footing.About Fiona: Fiona is an award winning investigative journalist who spent the first 20 years of her career in the Australian Broadcasting Corporation. She covered the 1991 coup in Soviet Union, the Balkans War and went on to be supervising producer of its current affairs equivalent of the BBC Newsnight. Her degree is in Sports Medicine and some 20 years ago she went into medical publishing. She has written for The Lancet and various other medical publications. For the past 8 years she has been working in the menopause space and is the co-founder  of the Menopause Research and Education Fund and the author of MenoWars - a look at the state of women's health through the lens of the current debates in menopause. Connect with Fiona:Book: MenoWars (available on Amazon and UK bookstores)Charity: Menopause Research and Education FundRelated Episodes You'll Love:Brain Health & Menopause: What Science Really SWhat did you think of this episode? Click here and let me know!

Send a textWe preview the Hormone Harmony Summit, a free multi-day event that blends medical science, practical tools, and whole-person healing for perimenopause and menopause. Get your ticket here:Hormone Harmony SummitWe kick off with the essentials: what shifting estrogen and progesterone actually do, how to read labs like FSH and estradiol in context, and a clear-eyed look at hormone therapy—when it helps, how to personalize it, and who should consider alternatives. From there, we map the gut-hormone connection with insights on microbiome diversity, bile flow, vagal tone, and practical strategies for women who can't or don't want HRT: nutrition that supports estrogen metabolism, targeted probiotics, sleep and stress protocols, and realistic movement goals that change how you feel day to day.Learn more about our Hormone Harmony Speakers here. The summit also takes on the bigger picture. We examine how women's health got here—research gaps, outdated dogma, brushed-off symptoms—and what genuine, respectful care looks like now. Physical therapist-led strength training becomes a non-negotiable tool for lean mass, bone density, insulin sensitivity, and confidence, with simple templates to start safely. Then we make space for what the lab report can't hold: the emotional terrain of grief and identity shifts, the spiritual invitation to align with what matters, and energy practices that help you feel grounded and steady. We even explore career pivots and purpose at midlife with practical steps to evaluate risk and move toward work that fits who you are becoming.Whether you're 35 and wondering “is this normal?,” 55 and seeking clarity on HRT, or 70 and ready to give your past a compassionate frame, you'll leave with tools, language, and choices that respect your whole life. Join us live for Q&A and community, catch replays if your schedule is full, or grab the all-access pass for transcripts and resources. Subscribe, share with a friend who needs this, and leave a review to help more women find informed, compassionate midlife care.Welcome to the Art of Healing Podcast community. This podcast is devoted to helping you find what works on your journey to health and wellness. This podcast is devoted to providing information on many healing modalities. Learn more about:ReikiFunctional MedicineMeditationEnergy Healingand more!Learn more about Dr. Charlyce here. Never miss an episode of Art of Healing Podcast...the podcast devoted to helping you heal your mind, body and spirit.Sign up for my weekly newsletter, and never miss an episode along with other great content:Art of Healing PodcastStay in touch socially here:Healing Arts LinksLearn more about me and my offerings here:Healing Arts Health and Wellness

Trong video này, bạn sẽ học được 2 từ khóa mới. Hãy viết xuống và tiếp tục nghiên cứu thêm nhé.(1) Hormone Replacement Therapy(2) EstradiolHơn 17 triệu phụ nữ Việt Nam đang trong độ tuổi tiền mãn kinh hoặc mãn kinh - và Linh là một trong số đó.

What if your mood swings, anxiety, sleep issues, or loss of motivation aren't just "getting older?" What role does oxytocin really play in midlife, and why has it been overlooked for so long? In this episode, I'm joined by the brilliant hormone scholar Dr. Lindsey Berkson, and we dive into a part of menopause that almost no one is talking about—what's happening in your brain. We explore how hormones act as the body's Wi‑Fi system, and what happens when that signal gets disrupted. Could environmental toxins be hijacking not just estrogen and progesterone, but oxytocin too? And if so, how might that impact connection, libido, blood sugar, digestion, or even depression? This conversation gets bold, nuanced, and deeply eye-opening. Dr. Berkson also challenges mainstream narratives around hormone therapy. Were we misled about estrogen and breast cancer? Why do some women struggle with HRT while others thrive? And could detoxification and nutrient status be the missing link? If you've ever wondered why your body isn't responding the way you expected, you won't want to miss this one! In this episode, we uncover: How oxytocin impacts mood, sleep, libido, and connection in midlife. Why environmental toxins may disrupt your hormonal "Wi‑Fi." What makes some women struggle with hormone replacement therapy. How oxytocin supports blood sugar, digestion, and pain relief. Why estrogen and progesterone are more protective than you've been told. Listen now, and let's start asking better questions about what's really happening in menopause!     Sponsors Join our NEW weight loss peptide program TODAY Join our NEW Midlife RESET HRT Program TODAY Get 15% off Masszymes at bioptimizers.com/hormone  Get 50% off the Energy Reboot Program hackmyage.com use coupon code HORMONES50.     Are you in perimenopause or postmenopause and struggling with symptoms—but not getting the support you deserve? At Midlife Solutions, we specialize in hormone optimization for women in midlife. Our all-female clinical team offers telehealth care across all 50 U.S. states, with the ability to prescribe bioidentical estrogen, progesterone, testosterone, and thyroid medication.   Book your FREE Hormone Discovery Call Find out what's really driving your symptoms and what your next best steps are.   Visit the website: https://karenmartel.com   Shop the Midlife Solutions Store Over-the-counter bioidentical hormone creams and oils — no prescription needed. Including: • Progesterone • Estrogen Face Cream • Vaginal Moisturizer and more!   Take the Hormone Quiz Discover hidden hormone imbalances that could be driving your symptoms. Get personalized results (and yes, they may surprise you).   Women's Peptide Weight Loss Program Clinically guided, hormone-aware weight loss for midlife women.   Midlife RESET HRT Program A complete, supportive approach to hormone replacement therapy in midlife.   Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert   Karen's Facebook Karen's Instagram

In this special Fan Mail Friday re-run, originally recorded during our 36th-anniversary trip to Kona, Jay and I dive into your candid questions about marriage—intimacy after babies, navigating NFP, dating on a budget, perimenopause and HRT, staying close in busy seasons, and why Christ at the center changes everything. It's honest, practical, and hope-filled (heads-up: rated “M” for Marriage). If you missed it the first time—or need the encouragement again—this one's for you. Show up for your marriage—you'll be encouraged.Prime Sponsor: No matter where you live, visit the Functional Medical Institute online today to connect with Drs. Mark and Michele Sherwood. Go to ⁠homeschoolhealth.com⁠ to get connected and see some of my favorite items. Use coupon code HEIDI for 20% off!Lifestone Ministries | ⁠Lifestoneministries.com/heidi⁠Show mentions: ⁠heidistjohn.com/mentions⁠Website | ⁠heidistjohn.com⁠Support the show! | ⁠donorbox.org/donation-827⁠Rumble | ⁠rumble.com/user/HeidiStJohn⁠YouTube | ⁠/ @heidistjohnpodcastInstagram | ⁠@heidistjohn⁠Facebook | ⁠Heidi St. John⁠X | ⁠@heidistjohn⁠⁠Faith That Speaks⁠ Online CommunitySubmit your questions for Fan Mail Friday | ⁠heidistjohn.net/fanmailfriday⁠

Are hormones making you gain belly fat? Is menopause really breaking your metabolism, or is something else going on? And does hormone replacement therapy help or hurt body recomp after 40?Body recomp, weight loss, hormone health, and women's fitness all collide in this conversation with Dr. Maria Sophocles, a board-certified OBGYN and nationally recognized menopause expert with 30 years of clinical experience. We break down why women lose muscle, gain abdominal fat, and struggle with metabolism during perimenopause and menopause even when nutrition, macros, and strength training are dialed in.We unpack what estrogen, progesterone, and testosterone actually do for fat distribution, muscle building, insulin sensitivity, and longevity. We also tackle the biggest fear head-on: does HRT cause weight gain?If you care about lifting weights, strength training over 40, and sustainable weight loss, this episode brings clarity instead of confusion.Today, you'll learn all about:0:00 – Menopause and weight fears5:33 – Why belly fat increases9:15 – Hormones vs metabolism myths13:56 – Muscle loss and calorie needs20:18 – Does HRT cause weight gain27:13 – Estrogen and fat distribution28:24 – Progesterone and sleep effects31:24 – Testosterone and muscle building34:16 – Labs and doses38:31 – Health risks and best time to start HRT45:30 – Four HRT takeawaysEpisode resources:Instagram: @mariasophoclesmd Website: mariasophoclesmd.com Book: The Bedroom Gap: Rewrite the Rules and Roles of Sex in MidlifeTED Talk: What happens to sex in midlife? A look at the "bedroom gap"YouTube: @drmariasophocles 

FDA Removes Black Box Warning on Estrogen: HRT Game-Changer for Women's Health After 23 years, the FDA removed the black box warning on estrogen products—a landmark decision transforming hormone replacement therapy (HRT) for women. In this episode of the Mortar and Pestle podcast, hosts Mike De Lisio and Sebastian Dennison discuss this breakthrough with Sara Hover, Senior Director of Clinical Services at PCCA.   What You'll Learn: Why the 2002 Women's Health Initiative study was flawed and created decades of HRT concerns The timing hypothesis: why age matters when starting hormone replacement therapy Synthetic vs. bioidentical hormones and their clinical differences Oral estrogen delivery systems and safety implications Shared decision-making between patients, prescribers, and pharmacists Why compounded HRT solutions matter for patients who don't fit commercial products Hormone testing modalities and why multiple testing methods are essential Vaginal estrogen's role in preventing UTIs and hip fractures How pharmacists can educate providers and patients on HRT safety   Topics Covered: Black box warning removal, hormone replacement therapy, bioidentical hormones, menopause management, compounding pharmacy, women's health, estrogen, patient monitoring, HRT dosing strategies   Perfect for: Compounding pharmacists, healthcare providers, and anyone seeking evidence-based information on hormone replacement therapy.   Links: Why VersaBase Cream Is Your Best Choice for Women's HRT The Vaginal Microbiome, Menopause & HRT A Personalized Approach to HRT for Perimenopausal Women Backed by Science: Anhydrous VersaBase® HRT Optimizing the Patient Experience with the Right HRT Base: Insights from the Webinar

Have you heard about the DUTCH test or urine testing for hormones , but when you saw the price you were shocked? You hear that it's important, but not sure if it's worth the price and are looking for alternatives. Then this episode is for you. Today I'm sitting down with my biohacking buddie Dr Amy Killen, who is a leader in women's health, regenerative medicine and longevity, and just spent six months combing through every study she could find on estrogen metabolites and hormone testing We cover What 22+ studies actually show about estrogen metabolites and breast cancer If DUTCH testing is helpful or unnecessary Labs that truly matter for longevity Which tests can help time HRT or track menopause onset The strongest lifestyle habits for extending our healthspan What's the number one treatment for skin health in menopause The top three longevity habits for women And so much more   Amy B. Killen, M.D., specializes in women's longevity–specifically hormone optimization and regenerative medicine–using research-backed and evidence-based interventions so women can thrive during their Queen Phase™.  She's a board-certified former Emergency Medicine physician who has dedicated the past dozen years to honing her expertise in health optimization, integrating treatments like pioneering stem cell therapies, bioidentical hormones, and peptides with personalized lifestyle strategies and technology-driven decision-making.  As an entrepreneur, she co-founded and now serves as Chief Medical Officer of Humanaut Health, a longevity clinic franchise. She also founded and remains immersed in the Human Optimization Project (HOP), a female-focused supplement company that bridges innovative medical treatments with accessible wellness solutions.  She shares her expertise and reaches audiences through educational content creation on her website and Substack, international speaking engagements, podcasts, and various media outlets. Dr. Killen earned her bachelor's degree in Biomedical Science from Texas A&M University and then her doctor of medicine degree from UT Southwestern Medical School. She became Chief Resident while completing an Emergency Medicine residency at the University of Arizona. She lives in Salt Lake City, Utah, with her family of five. Disclaimer: This is not meant to be medical advice. Dr. Amy is a doctor, but not your doctor.   Supplements: www.hopbox.life , Clinics: www.humanauthealth.com Discount code ZORA Contact Dr. Amy Killen: Social:  @dr.amybkillen,  @humanauthealth @hopboxlife  Substack: The Good, Bad and Ugly of Estrogen Metabolite Testing https://dramybkillen.substack.com/p/the-good-bad-and-ugly-of-estrogen Website: www.dramykillen.com  Healthcare: www.humanauthealth.com  Supplements: www.hopbox.life 10% off code ZORA   Give thanks to our sponsors: Try Vitali skincare. 20% off with code ZORA here - https://vitaliskincare.com Get Primeadine spermidine by Oxford Healthspan. 15% discount with code ZORA ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ - http://oxfordhealthspan.com/discount/ZORA Get Mitopure Urolithin A by Timeline. 20% discount with code ZORA at https://timeline.com/zora Try Suji to improve muscle 10% off with code ZORA at TrySuji.com - https://trysuji.com Try OneSkin skincare with code ZORA for 15% off https://oneskin.pxf.io/c/3974954/2885171/31050   Join the Hack My Age community on: YouTube: https://youtube.com/@hackmyage Facebook Page: ⁠⁠⁠⁠⁠@⁠Hack My Age⁠     Facebook Group: ⁠⁠⁠⁠⁠⁠@⁠Biohacking Menopause⁠⁠⁠⁠⁠⁠ ⁠   Biohacking Menopause Private Women's Only Support Group: https://hackmyage.com/biohacking-menopause-membership/ Instagram: ⁠⁠⁠⁠⁠@⁠HackMyAge⁠    Website: ⁠⁠⁠⁠⁠⁠HackMyAge.com⁠    For partnership inquiries: https://www.category3.ca/  For transparency: Some episodes of Hack My Age are supported by partners whose products or services may be discussed during the show. The host may receive compensation or earn a minor commission if you purchase through affiliate links at no extra cost to you. All opinions shared are those of the host and guests, based on personal experience and research, and do not necessarily represent the views of any sponsor. Sponsorships do not imply medical endorsement or approval by any healthcare provider featured on this podcast.

In this clip from Bathroom Diaries, Dr. Sofia Din and Dr. Rob Frankel break down one of the most common mistakes people make with peptides: thinking one peptide can fix everything. Using a simple and hilarious analogy — "asking for one peptide is like going to a tire shop and buying just one tire" — they explain why peptides work best as a system, not a single quick fix. If you're curious about how peptides actually work, which combinations make sense, and why personalized protocols matter, this highlight is a must-watch.

Send a textFiona and Nik break down the latest evidence on menopause, HRT and cognition so you can feel confident when patients ask, “Should I be worried?”Plus: in our second Pearl in this episode,  practical tips for behaviour change that actually sticks, including how to spot those golden moments and use the STOP IT model to turn advice into action.Tune in for clear answers and real‑world support for primary care.Perfect for anyone in primary care who wants to feel informed, confident and ready for the inevitable “I saw this in the news...” conversation.Useful LinksBritish Menopause Society: Menopause linked to loss of grey matter in the brain, poorer mental health and sleep disturbance We are currently looking for 4 new clinicians to join the Red Whale team to help us create and curate our educational content. For more information, on the Join Us section of our website. https://www.redwhale.co.uk/join-usSend us your feedback podcast@redwhale.co.uk or send a voice message Sign up to receive Pearls here. Pearls are available for 3 months from publish date. After this, you can get access them plus 100s more articles when you buy a one-day online course from Red Whale OR sign up to Red Whale Unlimited. Find out more here. Follow us: Facebook, Instagram, LinkedInDisclaimer: We make every effort to ensure the information in this podcast is accurate and correct at the date of publication, but it is of necessity of a brief and general nature, and this should not replace your own good clinical judgement, or be regarded as a substitute for taking professional advice in appropriate circumstances. In particular, check drug doses, side-effects and interactions with the British National Formulary. Save insofar as any such liability cannot be excluded at law, we do not accept any liability for loss of any type caused by reliance on the information in this podcast.

The search for Nancy Guthrie entered its twelfth day with the recovery of the case's first significant physical evidence and the deployment of the FBI's elite tactical unit to Tucson.FBI agents searching desert roadways in the Catalina Foothills recovered a pair of black latex gloves from the area surrounding Nancy's home. The Pima County Sheriff's Department confirmed the discovery. The gloves resemble those worn by the masked individual seen in doorbell camera footage and are being tested for DNA and fingerprints. The forensic question at the center of this evidence — whether the glove interior touched skin directly — will determine if investigators can extract a usable DNA profile.The FBI's Hostage Rescue Team arrived in Tucson Wednesday, a tactical unit deployed when hostage recovery operations may be necessary. The FBI has not commented on HRT's presence, but their deployment twelve days into a case with no confirmed proof of life signals investigators may believe a recovery scenario is possible.Doorbell footage is undergoing advanced analytics including AI-enhanced facial geometry mapping, technology that attempts to identify features through the ski mask fabric. Investigators are also pursuing retail purchase records for the Ozark Trail backpack, ski mask, gloves, and other items visible in the footage, cross-referencing sales across Tucson-area retailers to build a timeline leading to identification.TMZ received a third note Wednesday from someone claiming to know the kidnapper's identity and demanding one bitcoin for the information — a separate individual from the original ransom sender. The original ransom bitcoin wallet also showed its first activity, though the transaction's significance is unknown.The Pima County Sheriff's Department has not held a press briefing in nearly a week. Nancy Guthrie has a pacemaker, requires daily medication the sheriff himself has called potentially fatal to miss, and cannot walk fifty yards on her own. Both ransom deadlines have passed. No proof of life. No confirmed contact with whoever took her. Day twelve and counting.#NancyGuthrie #NancyGuthrieMissing #SavannahGuthrie #FBISearch #TrueCrimeToday #NancyGuthrieKidnapping #PimaCounty #HostageRescueTeam #ChrisNanos #TrueCrimeJoin Our SubStack For AD-FREE ADVANCE EPISODES & EXTRAS!: https://hiddenkillers.substack.com/Want to comment and watch this podcast as a video? Check out our YouTube Channel. https://www.youtube.com/@hiddenkillerspodInstagram https://www.instagram.com/hiddenkillerspod/Facebook https://www.facebook.com/hiddenkillerspod/Tik-Tok https://www.tiktok.com/@hiddenkillerspodX Twitter https://x.com/TrueCrimePodListen Ad-Free On Apple Podcasts Here: https://podcasts.apple.com/us/podcast/true-crime-today-premium-plus-ad-free-advance-episode/id1705422872This publication contains commentary and opinion based on publicly available information. All individuals are presumed innocent until proven guilty in a court of law. Nothing published here should be taken as a statement of fact, health or legal advice.

Twelve days after Nancy Guthrie was allegedly abducted from her Catalina Foothills home, the FBI has recovered its most significant physical evidence yet — a pair of black latex gloves found along a desert roadside less than two miles from her house. The gloves resemble those worn by the masked individual seen in doorbell camera footage released earlier this week and are now being tested for DNA and fingerprints.FBI agents spent Wednesday conducting an extensive ground search along roadways, washes, pulloffs, and culverts surrounding Nancy's neighborhood — terrain defined by thick desert brush, winding roads, and zero streetlights due to Pima County's dark-sky ordinances. The FBI's Hostage Rescue Team has also been deployed to Tucson, a tactical unit reserved for scenarios involving potential hostage recovery operations.The doorbell footage is now undergoing advanced analytics including AI-enhanced facial geometry mapping — technology that attempts to identify facial features through the ski mask fabric. Investigators are also cross-referencing retail purchase records for every identifiable item in the footage across Tucson-area stores, building a purchase timeline that could lead to a name.New developments include a third note received by TMZ — not from the kidnapper but from someone claiming to know the kidnapper's identity and demanding one bitcoin for the information. The original ransom bitcoin wallet also showed its first activity since the case began.Meanwhile, the Pima County Sheriff's Department has not held a press briefing in nearly a week despite recovering physical evidence, deploying HRT, receiving over four thousand tips in twenty-four hours, and running advanced forensic analysis on the footage. Their stated threshold for a briefing — a "significant development" — raises serious questions about what this agency considers significant.Nancy Guthrie has a pacemaker, requires daily medication the sheriff has called potentially fatal to miss, and cannot walk fifty yards unassisted. Day twelve. No proof of life. No confirmed contact with whoever took her. And the lead agency won't step in front of a camera.#NancyGuthrie #SavannahGuthrie #NancyGuthrieMissing #PimaCountySheriff #FBISearch #CatalinaFoothills #TrueCrime #HiddenKillers #NancyGuthrieKidnapping #ChrisNanosJoin Our SubStack For AD-FREE ADVANCE EPISODES & EXTRAS!: https://hiddenkillers.substack.com/Want to comment and watch this podcast as a video? Check out our YouTube Channel. https://www.youtube.com/@hiddenkillerspodInstagram https://www.instagram.com/hiddenkillerspod/Facebook https://www.facebook.com/hiddenkillerspod/Tik-Tok https://www.tiktok.com/@hiddenkillerspodX Twitter https://x.com/TrueCrimePodListen Ad-Free On Apple Podcasts Here: https://podcasts.apple.com/us/podcast/true-crime-today-premium-plus-ad-free-advance-episode/id1705422872This publication contains commentary and opinion based on publicly available information. All individuals are presumed innocent until proven guilty in a court of law. Nothing published here should be taken as a statement of fact, health or legal advice.

In this episode of the progesterone series, Dr. Brendan McCarthy — Chief Medical Officer of Protea Medical Center in Tempe, Arizona — explores the often misunderstood relationship between progesterone, estrogen, and breast health. For decades, women have been taught to fear their breasts and fear hormones. While awareness matters, fear is disempowering — and it has left many women confused about what's actually happening in their bodies. In this episode, we discuss: Why breast tissue is dynamic, not static How estrogen stimulates growth and progesterone restores balance The role of progesterone in breast tissue maturation and architecture Why dense or fibrocystic breasts often reflect unopposed estrogen How restoring ovulation and progesterone can reduce breast pain and density in some women The difference between natural progesterone vs synthetic progestins Where the fear around progesterone and breast cancer really came from Progesterone is not something to fear — it is a hormone of organization, balance, and maturation. Understanding how it works allows women to approach breast health with clarity instead of anxiety.

In part two of our menopause series, we unpack common myths and misinformation about perimenopause, menopause, and hormone replacement therapy. Many women are treated in fragments – this episode brings the conversation back into the exam room with practical, patient-centered guidance. We continue our conversation with Sharon Malone, MD, board-certified OB-GYN and chief medical advisor for Alloy Women’s Health, on how perimenopause is diagnosed clinically (often without definitive lab tests), which symptoms should raise red flags, and why HRT is never a one-size-fits-all yes-or-no decision. Credits Host: Neha Pathak, MD, FACP, DipABLM Producer/Editor: Lauren Summers Show Notes: Lauren Summers Guest: Sharon Malone, MD See omnystudio.com/listener for privacy information.

SummaryIn this episode, Anna Parker-Naples discusses the profound impact of perimenopause on women's health, particularly focusing on the respiratory system and the importance of breathwork. She shares her personal experiences with hormonal changes, mental health challenges, and the journey towards understanding and managing these symptoms through breathwork techniques. The conversation emphasizes empowerment through knowledge and practical tools for women navigating this transitional phase of life.TakeawaysBreathwork can be a powerful tool for healing.Perimenopause symptoms can be challenging to navigate.Understanding hormonal changes is crucial for health.Mental health issues may arise during perimenopause.HRT can help rebalance hormonal levels.The respiratory system is affected by hormonal changes.Breathing techniques can alleviate symptoms.Empowerment comes from knowledge and self-care.Women often lack support during perimenopause.Breathwork can improve overall well-being.Follow Links:Get the Influential Breathwork Syllabus here:⁠https://www.influentialbreathwork.com/syllabus⁠Follow Anna Parker-Naples onInstagram: ⁠https://www.instagram.com/annaparkernaples⁠LinkedIn: ⁠https://www.linkedin.com/in/annaparkernaples⁠

Elizabeth has the church giggles and Andy doesn't know how to lunch! Topics include: goat cheese, tradwife drama, barn coats, HRT, ER visits, and more. Check out our new True Crime podcast: BETH'S DEAD Learn more at: https://www.patreon.com/cw/BethsDead Support NLR Join Patreon for bonus episodes! Buy the Merch! Find us on Instagram Find us on TikTok⁠⁠ Watch us on YouTube Shop our Amazon recommendations Here ▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬ Chapters: 00:00 Intro 04:48 ADHD Journey 08:50 Fancy Cheesesteak 11:13 Lunch Etiquette 19:08 Ad Break 20:48 King Of Kong 21:43 Hormone Therapy 26:07 Clothes Make The Man 27:21 Goat Cheese 29:41 Ballerina Farms 44:34 Bomb In The Butt Learn more about your ad choices. Visit megaphone.fm/adchoices

Welcome to Part 1 of our special bone health mini-series, featuring Dr. Jocelyn Wittstein, Dr. Jessica Shepherd, personal trainer Debra Atkinson, and PhD researcher Dr. Darren Candow. In this episode, we discuss the impact of contraceptive use on bone health, especially in young women, and explore how underfueling and relative energy deficiency can contribute to serious bone health issues early in life. We highlight the strong connection between thyroid health and bone health, and clarify how frequently, how much, and how intensely we should strength train to best support our bones. We examine the potential long-term benefits of vibration plates, address concerns with current osteoporosis screening guidelines, and explain why assessing women's bone health earlier is crucial. Finally, we review the latest research on creatine monohydrate and its promising impact on bone health. I sincerely hope you enjoy Part 1 of this mini-series, which sets the stage for understanding lifelong bone health. IN THIS EPISODE, YOU WILL LEARN: How underfueling, overtraining, and oral contraceptives can limit bone development  The value of strength training and impact-based exercise for preserving bone density, supporting metabolic health, and reducing fracture risk How even a few minutes of impact exercise per day can stimulate bone strength  How vibration plates can complement strength and impact training Why declining estrogen during perimenopause and menopause increases the risk of osteoporosis and fractures as women age The benefits of weight training, resistance exercises, Pilates, and water aerobics for improving bone density and maintaining muscle strength How creatine supplementation combined with resistance training or structured exercise can help preserve bone strength in postmenopausal women How creatine alone, without physical activity, shows no meaningful benefit Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow  Cynthia's Menopause Gut Book is on presale now! Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Connect with Dr. Jocelyn Wittstein On the Duke Health website On Instagram The Complete Bone and Joint Health Plan, co-authored by Jocelyn Wittstein, MD, and Sydney Nitzkorski, MS, RD, is available on Amazon and at Barnes & Noble, and from most bookstores. Connect with Debra Atkinson On her website The Flipping 50 Podcast On Social Media: @flipping50tv Connect with Dr. Jessica Shepherd Sanctum Med and Wellness On Instagram: Jessica Shepherd or Modern Meno Dr. Shepherd's new book, Generation M, is available in-store or online from Barnes and Noble or on Amazon. Connect with Dr. Darren Candow On Instagram On X University of Regina Featured Episodes Ep. 467 Bone & Joint Health Tips for Women 40+ with Jocelyn Wittstein                              Ep. 321 Muscle, Bone & Joint Health in Menopause with Debra Atkinson                    Ep. 424 Menopause 101: Symptoms, HRT, and a Bio-Individual Approach with Dr. Jessica Shepherd Ep. 301 Creatine: The Best Supplement for Better Bones & Brain Health with Dr. Darren Candow

In this episode of the Love Your Life Show, I sit down with Dr. Maria Sophocles to talk about midlife sexuality and why so many women experience changes in desire as they move through perimenopause and menopause. We explore the bedroom gap, sexual burnout in women, and the many reasons women find themselves wondering why they no longer want sex in midlife. From body image and sexual desire to the role hormones and stress play, this conversation sheds light on what is actually happening and why you are not broken. We also talk about topics women are rarely given clear guidance on, including menopause and sex, medications that affect libido, and why it can feel so uncomfortable to talk to doctors and partners about sexual health. Dr. Maria shares practical, doable steps women can take today to feel more connected to their bodies and better informed about women's sexual health after 40. In this episode, we cover: Why libido changes after menopause and during perimenopause What sexual burnout looks like and why it is so common How body image impacts sexual desire in midlife The bedroom gap and mismatched expectations between partners Prescription medications that may be affecting libido How to talk to your doctor about sex and get real support If you have ever felt confused, frustrated, or alone when it comes to sex in midlife, this episode on the bedroom gap with Dr. Maria Sophocles and Susie Pettit will help you understand what is going on and what you can do next. If you liked this show, you'll like the past conversation I had with Dr. Maria!  Rethinking Menopause & HRT on Apple Podcasts https://podcasts.apple.com/us/podcast/rethinking-menopause-hrt-your-best-self-starts-now/id1434429161?i=1000713365898 Rethinking Menopause & HRT on Spotify https://open.spotify.com/episode/5TwRaLgGLrmxBzLlT7vpBu?si=Hl3CyADmTCKrAIkgD2QxPg   If you already listened to that and want more about “duty sex” and midlife sexuality, don't miss this conversation with Dr Sonia Wright: Let's Talk about Sex with Dr. Sonia Wright on Apple Podcasts https://podcasts.apple.com/ph/podcast/130-lets-talk-about-sex-with-dr-sonia-wright/id1434429161?i=1000507532904 Let's Talk about Sex with Dr. Sonia Wright on Spotify https://open.spotify.com/episode/3kPZokWJmNAFnKunNP0SnK?si=bgimi9afQhGSIkxshn2ikQ   Get all the links we mentioned and connect with Dr Maria Sophocles go here

For years, women have been told cholesterol doesn't really matter — or that as long as you're "metabolically healthy," you don't need to worry. In this episode, Tara shares why she no longer believes that… and how her own bloodwork forced her to rethink everything she once taught. Despite being fit, metabolically healthy, and doing "all the right things," Tara discovered she has genetically driven high cholesterol — something lifestyle alone couldn't fix. She explains why common tests like a coronary calcium score can give a false sense of security, and why genetics play a much bigger role in heart disease risk than the wellness industry admits. This episode challenges the oversimplified, feel-good cholesterol messaging online and replaces it with nuance, evidence, and real-life experience.   In Part 1, you'll learn: Why "high cholesterol doesn't matter" is misleading How Tara discovered her cholesterol issue was genetic Why being fit does not guarantee low cardiovascular risk The problem with relying only on standard heart scans The difference between lifestyle-driven and genetically driven cholesterol   WATCH ON YOUTUBE   -------------------------------------------------------------------------- HANGOUT WITH TARA ON FEBRUARY 24TH My Perimenopause Hangout is happening on February 24th and there's still time to join HERE. This isn't a fluffy webinar. It's a no-BS sit-down chat where I'll hand you a real-life roadmap for navigating midlife hormones + metabolism, so you finally know what to focus on (and what to stop wasting money on). You'll leave with strategies you can use the very next day. No starving yourself, no supplement graveyard. Show up live and you'll also get my best bonuses that only my clients typically get: Ultimate Midlife Blood Work Guide: The Tests Your Doctor Skips + Ranges That Actually Mean Something, (Not Just "You're Alive") Hormone Decoder Cheat Sheet: How To Talk To Your Doctor About the Right Hormones, Right Doses, Right Delivery, Even If Round 1 Failed Protein Made Simple Cheat Sheet: Help Figuring Out Your Daily Target + Meal Ideas & Easy Ways To Hit Your Protein Goals. The Magnesium Decoder Cheat Sheet: Which Form Does What + Electrolytes I Recommend. ​Save your free spot here! -----------------------------------------------------------------------------   Mentioned in this episode: MEGASPORE - Click HERE to grab this probiotic and use my practitioner code, which also gets you 10% off: TaraMegaSpore BON CHARGE - Save 15% when you when you shop HERE and use Tara's code: THORNE15 PALEOVALLEY - Get an automatic 15% discount applied when you click here to purchase. HRT Made Simple™ - Learn how to confidently speak to your doctor about the benefits of hormone replacement therapy so you can set yourself up for symptom-free, unmedicated years to come without feeling confused, dismissed, or leaving the medical office minus your HRT script. Hair Loss Solutions Made Simple™ – This course will teach you the best natural, highly effective, and safe solutions for your hair loss so you can stop it, reverse it, and regrow healthy hair without turning to medications. The Perimenopause Solution™ – My signature 6-month comprehensive hormonal health program for women in midlife who want to get solid answers to their hormonal health issues once and for all so they can kick the weight gain, moodiness, gut problems, skin issues, period problems, fatigue, overwhelm, insomnia, hair/eyebrow loss, and other symptoms in order to get back to the woman they once were. [FREE] The Ultimate Midlife Perimenopause Handbook - Grab my free guide and RECLAIM your confidence, your mood, your waistline and energy without turning to medications or restrictive diets (or spending a fortune on testing you don't need!).   [BOOK A 30-MINUTE SESSION WITH TARA HERE]

In this episode, Claudia breaks down why heavy bleeding, fibroids, and ovarian cysts become so common in perimenopause – and what's really driving them beneath the surface. You'll learn how low progesterone, poor estrogen metabolism, mineral imbalances, gut health, and improperly managed HRT can all contribute, and why monitoring matters when symptoms persist. In this episode, we cover: Why low progesterone and unopposed estrogen drive heavy periods and fibroid growth How HRT dosing and endometrial lining impact bleeding and clotting The role of minerals, detox pathways, and daily bowel movements in hormone clearance When cysts are normal and when to investigate further   MENTIONED IN THIS EPISODE:  Episode 95: Low Ferritin After 40: Do You Really Need Iron? What Your Labs Aren't Telling You   

Work With Me: (my fastest path to weight loss transformation for women over 40) Apply for ForeverWell Private Coaching  Turn podcast episodes into weight loss results: Sign up for Stop. Dieting. Forever. Friday weekly newsletter   Here's the thing nobody tells you about perimenopause lab work: your doctor is looking for disease, but you need someone looking for optimal function. Those are two completely different things. And that gap is keeping you stuck with "normal" test results while your body falls apart. I've worked with enough women to see the pattern. They're told their thyroid is fine based on one marker. Their hormones get tested on random days. Nobody checks fasting insulin even though their glucose looks perfect. And they walk out of appointments being told to eat less and move more when the real problem is being completely missed. This episode is about getting the complete picture before you make any decisions about HRT, peptides, or other interventions. Because half my clients didn't need what they thought they needed once we actually looked at what their body was doing.   FEATURED ON THE SHOW / RESOURCES Want to Work With Jennifer? Book a Consult Follow me on Instagram: @JenniferDentBrown Website: JenniferDent.com Oura Ring 

119. Microdosing for Midlife: Brain Science of Change (Week 2)Week 2 of Microdosing for Midlife explores estrogen, menopause, hormone therapy, and cognitive health—plus how psilocybin supports neuroplasticity.Episode SummaryThis episode marks Week 2 of Microdosing for Midlife, a 12-week audio series exploring how psilocybin microdosing for women intersects with hormonal change, emotional regulation, and cognitive resilience during midlife.In this installment, April Pride expands on a central question that surfaced after Week 1: whether being “spared” classic menopausal symptoms—or choosing not to take hormone replacement therapy—puts women at greater risk for cognitive decline. Drawing from current research, April reframes the fear-driven narrative around menopause, estrogen, and dementia, offering a more nuanced and reassuring understanding of what actually shapes long-term brain health.The episode also explores estrogen's role as a neuroprotectant, how the midlife brain becomes more vulnerable to stress-based patterning, and why psychedelics like psilocybin may support neuroplasticity by softening rigid survival scripts. Through personal reflection and lived experience, April illustrates how subtle shifts in perception—not emotional erasure—can change one's relationship to anxiety, grief, and uncertainty.This episode functions as an audio companion to the written Week 2 essay, adding scientific context, integration insights, and real-life application without replacing the original post.

Free Webinar - Wednesday February 11 - https://www.hackmydna.com/sarah Previous episode with Kash on HRT - https://www.youtube.com/watch?v=7Jaa_kjm-K0Blueprint Live Program - Waitlist - https://www.sarahkleinerwellness.com/the-bio-individual-blueprint-waitlistBlueprint OnDemand (get access now & get a custom protocol) - https://www.sarahkleinerwellness.com/offers/2oECuhhC/checkout?coupon_code=ONDEMANDSauna Article - understanding protocols - timing - when binders are OK and when to skip & how to support your detox pathways - https://open.substack.com/pub/sarahkleinerwellness/p/binder-with-your-sauna-not-so-fast?utm_campaign=post-expanded-share&utm_medium=webTanning Bed Article - the lost science of UV light & why all tanning beds and light therapy isn't the same - https://sarahkleinerwellness.substack.com/p/tanning-beds-uv-light-and-the-lostFertility Signals Bundle with Deuterium Protocol - https://www.sarahkleinerwellness.com/offers/NUzm6KoY/checkout?coupon_code=RMDYDeuterium only course - https://www.sarahkleinerwellness.com/offers/Qj8as8ep/checkout21 Day Leptin Reset (click here for my most foundational program) - https://www.sarahkleinerwellness.com/offers/NNFJ5zEi/checkoutLeptin Resistance Quiz (click here to take the free quiz) - https://www.sarahkleinerwellness.com/21dayleptinquestionaire_________Sponsored By:→ VivaRays | This episode is sponsored by VivaRays - VivaRays Blue - code YOGI https://vivarays.com/yogi→ Troscriptions | For an exclusive offer, go to https://www.troscriptions.com/SARAHK for 10% off your first non subscription order._________Timestamps:00:00 Introduction and Podcast Overview01:25 Early Access and Special Offers on Substack03:27 Personal Challenges and Real-Life Struggles05:34 Gene Testing and Mitochondrial Health12:21 Menopause, Hormones, and Light Therapy14:35 Nervous System Support and Stabilization16:56 Sauna Protocols and UVB Light Therapy21:48 Methylene Blue and Supplementation23:26 Blue Blockers and Circadian Rhythm25:12 Understanding Low Leptin and Weight Loss25:28 Repletion Protocol for Low Leptin25:59 Mineral Loading and System Repletion26:36 Addressing Circadian Rhythms and Stress27:01 Balancing Carbs and Blood Sugar27:11 Personalized Protocols and Blueprint Program29:09 Fertility in Your Forties30:35 Deuterium Depletion and Mitochondrial Health36:00 Light Environment and Mitochondrial Function43:09 Histamine Intolerance and Liver Support45:43 Final Thoughts and Resources——— This video is not medical advice & as a supporter to you and your health journey - I encourage you to monitor your labs and work with a professional!________________________________________Get all my free guides and product recommendations to get started on your journey!https://www.sarahkleinerwellness.com/all-free-resourcesCheck out all my courses to understand how to improve your mitochondrial health & experience long lasting health! (Use code PODCAST to save 10%) -  https://www.sarahkleinerwellness.com/coursesMy free product guide with all product recommendations and discount codes:https://www.canva.com/design/DAF7mlgZpJI/xVyE4tiQFEWJmh_Xwx8Kbw/view?utm_content=DAF7mlgZpJIFree Webinar on Light & Health (includes free light bulb guide) - https://www.sarahkleinerwellness.com/mycircadianapp-free-webinarGet Early Access to Podcast Episodes & my Seasonal Food Course + UVB+Red Light Therapy course for free -  https://open.substack.com/pub/sarahkleinerwellness/p/uvbred-light-protocol?r=5eztl9&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true

In this powerful and refreshingly honest conversation, Wendy sits down with Dr. Maria Sophocles, menopause expert and author of The Bedroom Gap, to talk about what's really happening to our bodies, hormones, and intimate relationships in midlife.   From hormone replacement therapy and surgical menopause to desire, pleasure, and closing the “bedroom gap,” this episode busts outdated myths, delivers science-backed truth, and offers real hope for feeling better—physically, emotionally, and relationally—at this stage of life.   What You'll Learn: Why hormone replacement therapy (HRT) is about more than symptom relief—it's about long-term health The truth about menopause, bone health, brain health, and longevity What the “bedroom gap” is and why it widens in midlife relationships How intimacy, connection, and pleasure can evolve (and improve) after 40 Simple, empowering ways to reclaim confidence and connection in this chapter of life  

If you're over 40 and suddenly dealing with bloating, constipation or diarrhea, weight gain, brain fog, skin issues, or painful periods, this episode explains why your gut—not your willpower—is the real place to start.In this episode, Melissa Eich breaks down why gut health is the most overlooked foundation of healing in perimenopause, why food sensitivity testing often causes more harm than clarity, and how functional testing like the GI Map reveals root causes that conventional GI care frequently misses.If you've been told to “eat more fiber,” “manage stress,” or given another prescription without real answers, this conversation will help you understand why your body feels off—and what actually works.Ready to Heal Your Gut? Enroll here: https://l.bttr.to/doi1xIn This Episode, You'll Learn:Why gut health is ground zero for healing in midlifeHow gut dysfunction drives hormone imbalance, fatigue, and stubborn weight gainThe gut–estrogen connection and why detoxification mattersHow leaky gut contributes to bloating, food reactions, brain fog, and skin issuesWhy food sensitivity tests are misleading (and often harmful)What the GI Map test reveals that colonoscopies and standard labs don'tHow gut inflammation worsens perimenopause symptoms like mood swings, hot flashes, and heavy periodsWhat a personalized, holistic gut health program actually looks likeWhy nervous system regulation is essential for lasting gut healingWhy Gut Health Matters More After 40During perimenopause, your body becomes far less tolerant of stress, inflammation, under-fueling, and chronic gut dysfunction. Your gut plays a key role in nutrient absorption, immune health, neurotransmitter production, and estrogen detoxification.When the gut is inflamed or imbalanced, estrogen recirculates instead of being eliminated—leading to worsening hormone symptoms, persistent weight gain, and feeling “off” no matter what you try. This is why gut healing must come before focusing on hormones, HRT, or weight loss.What the GI Map Test RevealsThe GI Map stool test provides insight into:Beneficial and pathogenic bacteriaDysbiosis and overgrowthGut inflammation and permeabilityImmune activityEstrogen detox pathwaysThis allows for a targeted, personalized healing plan instead of guesswork.A Holistic Gut Health Program for PerimenopauseMelissa shares a limited-time comprehensive gut healing package that includes:At-home GI Map testingPersonalized lab interpretationA 12-week custom gut healing protocolTargeted supplements only if neededA 21-day gut reset focused on nourishment, not restrictionNervous system regulation toolsThree follow-up sessions for real support and progressThis approach focuses on restoring digestion, supporting hormone balance, and helping you feel clear, steady, and at home in your body again.Explore the program here: https://l.bttr.to/doi1xWho This Episode Is ForThis episode is for you if:You're bloated or constipated despite “doing everything right”Weight loss no longer works the way it used toYou've tried elimination diets, probiotics, or food sensitivity testingYou're dealing with gut and hormone symptoms at the same timeYou want root-cause healing—not another quick fixKey SEO Topics: Perimenopause gut health, GI Map testing, holistic gut health, gut health program perimenopause, dysbiosis, leaky gut, estrogen detoxification, hormone imbalance after 40, brain fog and gut health

In Part 1 of this conversation, Jamie sits down with nurse practitioner Jaclyn Taylor to pull wellness out of the “buzzword” category and into real life. They talk about why so many people feel stuck—fatigued, anxious, gaining weight, losing motivation—and why the first step isn't a perfect plan…it's being listened to. Jaclyn breaks down what the Your Health Wellness Program offers, how bioidentical hormone replacement therapy works, and why “normal labs” don't always mean you're actually okay. This episode is for anyone who's been powering through, silently struggling, or wondering if feeling better is still possible. www.YourHealth.Org

Shawn & Janet Needham, R.Ph., talk with Lori Krajewski about how women can find the HRT that works for them. Lori Krajewski Facebook | http://www.facebook.com/RootLoriKaye Instagram | https://www.instagram.com/lori.krajewski/ TikTok | https://www.tiktok.com/@openly.gray.lorikaye Website | http://www.therootbrands.com/freedomnurse Health Solutions Instagram | https://www.instagram.com/health_solutions_shawn_needham/ TikTok | https://www.tiktok.xcom/@healthsolutionspodcast Facebook | https://www.facebook.com/HealthSolutionsPodcast Moses Lake Professional Pharmacy Website | http://mlrx.com.com/ Facebook | https://www.facebook.com/MosesLakeProfessionalPharmacy/ Shawn Needham X| https://x.com/ShawnNeedham2 Shawn's Book | http://mybook.to/Sickened_The_Book Additional Links https://linktr.ee/mlrx

Hot flashes, hormones, mood swings… oh my.

BE WARNED: It's LuAnna, and this podcast contains honest, upfront opinions, rants, bants and general explicit content. But you know you love it.On this week's LuAnna: the girls tackle dry winter bodies, reveal summer holiday plans, Anna becomes the new poster girl for HRT, a listener faces some red flags around money and power in her relationship and the most memorable Valentine's story involving roleplay and a BB gun.Plus, Roblox does something right for child safety, an sad update, we crown another truly unhinged Weirdo of the Week and Apple subscriptions get it in the ear from Lu.GRAB YOUR TICKETS FOR THE BIG PARTY AT EVERYTHINGLUANNA.COMRemember, if you want to get in touch you can: Email us at luanna@everythingluanna.com OR drop us a WhatsApp on our brand new number 075 215 64640Please review Global's Privacy Policy: https://global.com/legal/privacy-policy/

"They look magical on Instagram, but they're not magic. Micronutrients have to be in place, your hormones have to be in place," explains Elizabeth Yurth, M.D., Elizabeth Yurth, M.D., a double board-certified physician in Physical Medicine & Rehabilitation and Anti-Aging/Regenerative Medicine, joins us on the podcast to discuss why peptides are much more than an Instagram trend, what forms of peptides might be most beneficial, and how to be mindful of safety and quality if you're trying to incorporate them into your own protocol. Show Notes (00:00) Introduction to peptides (02:31 ) Endogenous vs. exogenous peptides (03:15) Growth hormone (05:25) Peptides for muscle & immune health (07:19) The peptide explosion & safety concerns (08:11) BPC 157: A remarkable peptide? (10:38) Quality & sourcing of peptides (16:54) Anti-aging & HRT (20:54) Peptides for cognitive health (24:27) COVID-19 & neuroinflammation (27:12) Addressing chronic inflammation & resilience (39:12) The importance of nutrition & lifestyle Referenced in this episode: Follow Dr. Yurth on Instagram (@dryurth) Find out more about her work (https://boulderlongevity.com/about/dr-elizabeth-yurth) We hope you enjoy this episode, and feel free to watch the full video on YouTube! Whether it's an article or podcast, we want to know what we can do to help here at mindbodygreen. Let us know at: podcast@mindbodygreen.com.Referenced in the episode: Learn more about your ad choices. Visit megaphone.fm/adchoices

Listening to the wisdom of the body and healing thyself is the ultimate flex. Not your peptide and supplement stack.In an era of every biohacker selling their supplements and peptide stack, every integrative and regular physician flogging their HRT and TRT, I'm not even remotely interested in their offerings.What's always fascinated me, is the idea that I can source this healing power from within.Taking a pill or a drug?Not a flex, in my world.It's the opposite—dependency and a cop-out.The sales pitch that you need a medication, supplement or machine in order to feel good, forever and ever—and you can't ever be without it?This is the ultimate snake oil.I'm inspired by the notion that we have the power to heal ourselves.Everyone can.THIS is the true flex in my world and in Anami Land: Connecting with our own bodies and highest wisdom as the oracle. As allies. Rather than an enemy and something to be subjugated.Today's episode is a replay of the Insta Live I did last week, with an additional introduction from me. We talk: A body glossary of reproductive issues and their symbolic meaningsExiting the “age of apology” and normalizing greatness. Not me though, muthafukkas, I never apologized. Unless you count this, the greatest non-apology EVAH! Winning, not whining Vaginal electrocution and lube forever OR being hot as fuck and rocking bikinis and surfing big waves at age 55. You choose.Body-positivity vaginas and cocks or superior, cosmically enlightened onesThe slow tiptoe and MLM scheme of outsourcing reproductive power, starting with Pap Smears and “abnormal cells” and ending in C-sections The root cause of ailments like incontinence, IVF, PCOS, difficult periods and menopause Why didn't her Oura ring stop her from having a C-section? It knows everything, right? Abortion-rabid “feminists” as the most self-oppressed women in society Flute-playing, articulate vaginas that make a man ejaculate or stop him from ejaculating—the ultimate “flex” Shooting ping pong balls is the normal, healthy baseline and minimum skill for all vaginas To receive access to my FREE masterclass: We Are the Elite! We Are Kung Fu Vaginas, click here.