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The Menopause Solution with Dr. Lauren Fitzgerald What was the black box warning? Why was it there? Why is it now gone? (2:09) An interesting symptom of perimenopause. (8:12) Progesterone will change your life! (9:52) The importance of monitoring your thyroid levels and the 10 most common low-thyroid symptoms. (14:20) Testosterone for women. (22:57) Her main issue with primary care doctors. (27:14) The role of peptides in her practice. (30:01) The buy-in. (30:47) Ranking the various applications of testosterone. (33:39) The BIG myths surrounding HRT. (36:03) It's not a business, it's a mission. (40:26) GLP-1s: Incredible tools when used appropriately. (41:40) Normal isn't OPTIMAL. (45:27) The missing element for MOST people. (55:51) Related Links/Products Mentioned Visit Pre-Alcohol by ZBiotics for an exclusive offer for Mind Pump listeners! ** Promo code MINDPUMP25 for 15% off first-time purchasers on either one-time purchases (3, 6, 12-packs) or subscriptions (6, 12-pack) ** MAPS 15 FORTY PLUS 50% half from Dec. 14-20th. Code DECEMBER50 at checkout. Mind Pump Store FDA to Remove 'Black Box' Warnings From Menopause Hormone Therapy. Here's Why. The WHI Study: How Misinterpretation of Hormone Therapy Data Hurt Women's Health Welcome to the 'menodivorce'. Why women aren't sweating marriage in a sea of hot flashes Estrogen Matters: Why Taking Hormones in Menopause Can Improve and Lengthen Women's Lives -- Without Raising the Risk of Breast Cancer Mind Pump #2502: Hormone Therapy for Aesthetics With Dr. Lauren Fitzgerald Mind Pump #2597: Before You Take Ozempic, Wegovy, or Mounjaro Listen to This! Muscle Mommy Movement Mind Pump Podcast – YouTube Mind Pump Free Resources Featured Guest/People Mentioned LAUREN FITZ, M.D. (@drlaurenfitz) Instagram Website Dr. William Seeds (@williamseedsmd) Instagram Peter Attia, M.D. (@peterattiamd) Instagram
Have you taken progesterone expecting calm, better sleep, or relief from PMS… only to feel more anxious, wired, or worse overall? You are not a failure—and progesterone is not failing you. Your body is responding exactly as physiology dictates. The issue is how progesterone is being delivered and metabolized. In this episode, Dr. McCarthy explains: What it means to be a progesterone reverse responder How progesterone normally supports mood and brain chemistry through allopregnanolone Why some women experience paradoxical anxiety, insomnia, or agitation The role of the 5-alpha reductase pathway in progesterone metabolism Why oral progesterone can overwhelm the brain in certain women How PCOS, topical testosterone, stress, insulin resistance, and ultra-processed diets can amplify reverse responses Why kinetics and delivery method matter just as much as dosage Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.
In this episode, Dr. Bill Campbell returns to the show to discuss a major pivot in his research from building muscle and optimizing fat loss to understanding menopause and its effects on women's body composition. After watching his wife struggle through a severe perimenopause transition that resisted every traditional fat loss strategy, Campbell uncovered a massive blind spot in the scientific literature: almost no research exists on fit, resistance trained women going through menopause. His public comments sparked hundreds of messages from women describing the same struggles including unexplained weight gain, muscle loss, energy crashes, and sleep disruption highlighting how poorly understood this phase of life truly is. Dr. Campbell breaks down what the best research does show. Menopause accelerates fat gain, shifts fat distribution toward the midsection, and produces measurable declines in muscle and bone mineral density. Many women experience weight loss resistance where standard diet and training approaches no longer produce results. He also digs into the nuance of hormone replacement therapy how progesterone and estrogen can dramatically improve sleep, anxiety, and energy, why estrogen appears anabolic for middle aged women, and why HRT's effect on body fat varies widely. Campbell clarifies the long standing confusion created by the 2002 Women's Health Initiative study, how its flawed interpretation suppressed HRT use for two decades, and why today's evidence supports earlier intervention under an evidence based physician. The conversation closes with clear, practical guidance for women entering perimenopause. Maintain a consistent fitness lifestyle, lift weights to protect muscle and bone, prioritize sleep, get annual bloodwork and DEXA scans, and consider HRT early if medically appropriate. Campbell emphasizes that lifestyle habits do not replace hormone therapy and hormone therapy does not replace lifestyle. Together they help women navigate the most dramatic physiological transition since puberty. Whether you're a coach, practitioner, or someone approaching this stage of life, this episode provides a much needed framework for understanding, preparing for, and managing menopause with strength and agency. Links: Anders Varner on Instagram Doug Larson on Instagram Coach Travis Mash on Instagram
This week on Real Food Stories, Heather breaks down the wild world of midlife nutrition in 2025 — from microdosing GLP-1s, oral semaglutide, and high-protein everything to cottage-cheese coffee, weighted vests, and the fiber frenzy. If nutrition felt chaotic this year, you're not imagining it.We revisit my most downloaded episodes on HRT confusion and upgrading your midlife kitchen, and she shares her own experience navigating hormone therapy around surgery — a perfect example of why women remain overwhelmed by inconsistent guidance.Underneath all the noise, one message stood out: women need clarity, strength, real food, and community.I close the episode with an invitation to join The Well Nourished Woman, her supportive space for women 40+ who want evidence-based guidance without the overwhelm.I would love to hear from you! What did you think of the episode? Share it with me :) Support the showLet's Be FriendsHang out with Heather on IG @greenpalettekitchen or on FB HERE.Let's Talk!Whether you are looking for 1-1 nutrition coaching or kitchen coaching let's have a chat. Click HERE to reach out to Heather.Did You Love This Episode? "I love Heather and the Real Food Stories Podcast!" If this is you, please do not hesitate to leave a five-star review on Apple or wherever you listen to podcasts.
What if the confusion around fasting and hormones isn't because the science is complicated, but because most people are using the wrong tools for the wrong goals? In this episode, I sit down with Dr. Mindy Pelz to get clear about what fasting actually does, when it helps, and when it backfires. This is a conversation about taking ownership of your metabolism instead of chasing trends that don't match your life. We talk about the viral moment from her Stephen Bartlett interview, how misinformation spreads, and what she learned from being at the center of it. Mindy breaks down her six core fasts, why women need a different strategy, and how to adjust your approach if you train hard. We get into cycle-based fasting, fertility, menopause, HRT, toxic load, peptides, creatine, apple cider vinegar, and the rise of GLP-1 drugs. If you've ever wondered how to use fasting without wrecking your energy or performance, this episode will give you a clearer path forward. Dr. Mindy Pelz is a bestselling author, educator, and functional health expert known as the fasting guru. Her books Fast Like a Girl and Age Like a Girl have helped millions of women rethink metabolic health, hormones, and aging, and she has led hundreds of thousands of people through community fasts that focus on real-world results, not quick fixes. What We Discuss: (00:00) How a Misquote Went Viral and Changed Mindy's Career (04:12) What the Internet Got Wrong About Testosterone and Fasting (11:19) The Biggest Fasting Mistakes Most People Still Make (17:05) The Six Core Types of Fasting and When to Use Each (23:28) Fasting for Gut Repair, Weight Loss, and Dopamine Reset (28:54) How Athletes and Active Women Should Adapt Their Fasts (34:04) Cycle-Based Fasting and Hormonal Timing for Women (43:00) Supplement Cycling, Autophagy, and Metabolic Flexibility (55:19) GLP-1 Drugs, Gut Health, and the Real Drivers of Hunger (59:31) The Long-Term Risks of Quick-Fix Weight Loss Trends (01:05:40) Fertility, Progesterone Needs, and Rethinking HRT (01:16:14) Menopause, Brain Rewiring, and Building Cognitive Strength (01:28:48) Peptides, ACV, and Final Insights Before Wrap-Up Thank you to our sponsors: Therasage: Head over to therasage.com and use code Be Bold for 15% off Air Doctor: Go to airdoctorpro.com and use promo code HUSTLE40 for up to $300 off and a 3-year warranty on air purifiers. Magic Mind: Head over to www.magicmind.com/jen and use code Jen at checkout. Momentous: Shop this link and use code Jen for 20% off Manna Vitality: Visit mannavitality.com and use code JENNIFER20 for 20% off your order Prolon: Get 30% off sitewide plus a $40 bonus gift when you subscribe to their 5-Day Program! Just visit https://prolonlife.com/JENNIFERCOHEN and use code JENNIFERCOHEN to claim your discount and your bonus gift. Amp fit is the perfect balance of tech and training, designed for people who do it all and still want to feel strong doing it. Check it out at joinamp.com/jen Find more from Jen: Website: www.jennifercohen.com Instagram: @therealjencohen Books: www.jennifercohen.com/books Speaking: www.jennifercohen.com/speaking-engagement Find more from Dr. Mindy Pelz: Website: www.drmindypelz.com Instagram: @dr.mindypelz TikTok: @drmindypelz YouTube: @drmindypelz
In this lively and unfiltered gathering, Dr. Fiona Lovely is joined by her beloved "Meno Besties," hormone specialist Karen Martel and longevity expert Zora Benhamou. This is a candid conversation between three leading voices who've been in the menopause advocacy space long before it was trending. They tackle the frustrating realities women still face, from doctors dismissing requests for hormone testing to the enduring stigma around the word "menopause" itself. The discussion delves into the critical need for education and self-advocacy, emphasizing that despite increased awareness, a shockingly low percentage of women are actually on hormone therapy. Fiona, Karen, and Zora break down the early, subtle signs of perimenopause that often go unrecognized and explain the rollercoaster of "wonky periods." They also provide crucial insights into the practicalities of hormone therapy, addressing why some women don't feel better initially, the importance of dosage adjustments, and why partnering closely with your prescriber is non-negotiable. The conversation takes a fascinating turn into how past trauma and nervous system health may influence one's response to HRT, highlighting the profound mind-body connection during this transition. This episode is a masterclass in navigating midlife health with clarity, humor, and the supportive solidarity of friends who truly get it. Connect with Karen and Zora: Karen Martel: karenmartel.com | Instagram: @karenmartelhormones Zora Benhamou: hackmyage.com | Instagram: @hackmyage Thank you to our sponsors for this episode:
Big pharma has officially crossed the line: 30-something women are being told they're in 'perimenopause,' and the recommendation (of course) is to start HRT. The truth is that they are tired, stressed, skipping meals, and feeling overwhelmed. In this ultra-sassy episode, Ronda breaks down the manufactured narrative driving this trend, the physiology that proves it wrong, and a real case from her clinic that highlights how widespread the misinformation has become. Younger women don't need hormone therapy - they need blood sugar support, a well-regulated nervous system, and a meal that isn't toddler leftovers. Want more clinical clarity like this? You need to be inside Clinical Academy where you get patient-ready protocols, a library of fully searchable trainings, and real-world resources that save time and make your patient care so much easier.
View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this "Ask Me Anything" (AMA) episode, Peter tackles a wide-ranging set of listener questions spanning lifespan interventions, exercise, cardiovascular risk reduction, time-restricted eating, blood pressure management, hormone therapy, diagnostics, and more. Peter reveals the single most important lever for extending healthspan and lifespan, and explains how he motivates midlife patients using the Centenarian Decathlon framework. He discusses the importance of addressing high apoB and cholesterol even in metabolically healthy individuals with calcium scores of zero, how to manage high blood pressure, and how to accurately evaluate metabolic health beyond HbA1c. Additional topics include time-restricted eating, practical considerations around ultra-processed foods, nuanced approaches to HRT for women and TRT for men, and why early and expanded screening for chronic disease—colonoscopy, PSA, coronary imaging, low-dose CT—can be lifesaving. He also offers insights into treating prediabetes, crafting exercise programs for those short on time, and safely incorporating high-intensity training in older adults. If you're not a subscriber and are listening on a podcast player, you'll only be able to hear a preview of the AMA. If you're a subscriber, you can now listen to this full episode on your private RSS feed or our website at the AMA #78 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here. We discuss: Introducing a wide-ranging AMA: practical perspectives on lifespan interventions, metabolic health, diet, hormones, diagnostics, and more [2:45]; Why exercise is the most powerful single intervention for lifespan and healthspan [4:15]; How Peter motivates midlife patients to prioritize exercise [6:00]; Why lifespan and healthspan should not be treated as competing priorities and how choosing sustainable interventions benefits both [9:30]; Why high apoB deserves treatment even in a metabolically healthy patient with a CAC score of zero [14:00]; Managing hypertension: ideal targets for blood pressure, lifestyle levers, and why early pharmacology matters [18:15]; Assessing metabolic health beyond HbA1c: fasting insulin, triglycerides, lactate, zone 2, and more [23:30]; How to avoid common self-sabotaging patterns by choosing sustainable habits over extreme health interventions [26:00]; Time-restricted eating: minimal effect beyond calorie control, implications for protein intake, and practical considerations for implementing it [28:00]; Ultra-processed foods: definitions, real-world risks, and practical guidelines for smarter consumption [30:30]; How women should prepare for menopause and think about hormone replacement therapy: early planning, symptom awareness, and guidance on HRT [36:45]; Testosterone replacement for aging men: indications, benefits, and safe clinical management [39:45]; Why Peter recommends earlier and more aggressive screening tests than guidelines suggest: colonoscopies, coronary imaging, PSA, Lp(a), and low-dose CT scans, and more [43:30]; Full-body MRI screening: benefits, limitations, potential false positives, and the importance of physician oversight [47:15]; Prediabetes: individualized treatment strategies using tailored combinations of nutrition, sleep, and training interventions [51:00]; Time-efficient training plans for people with only 30 minutes per day to exercise [53:00]; How to safely introduce high-intensity exercise for older adults [55:00]; Timed dead hangs and ripping phone books: a playful look at Peter's early attempts to impress his wife [57:15]; Peter's carve out: The Four Kings documentary about a golden era of boxing [1:01:15]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube
After 20 years of prescribing hormone replacement therapy to tens of thousands of patients, both in her clinic and through her telemedicine company Menrva, I have identified the critical gaps in how HRT is being prescribed, monitored, and optimized across the United States. This isn't about "should you" do hormones. This is about how to do them right. In this episode,I break down the 10 non-negotiables you need to know if you're considering HRT, currently on HRT, or feeling like your current protocol isn't working. From the biochemistry of bioidentical vs. synthetic hormones to why your gut health determines how well your estrogen gets metabolized, this is the master class your doctor should have given you, but didn't. We're talking about natural bioidentical hormones, the truth behind the Women's Health Initiative (spoiler: it was about Premarin and synthetic progestins, NOT bioidentical estrogen), and how to use precision medicine to guide YOUR hormone replacement therapy, not a one-size-fits-all protocol that leaves 50% of women undertreated and 25% overtreated. Discover The 10 Non-negotiables: #1 - Bioidentical Is NOT a Buzzword #2 - Your Symptoms Are Metabolic Signals #3 - The WHI Study Was About Premarin & Provera #4 - Your Gut & Estrogen Are in Constant Conversation #5 - Testosterone Is a Woman's Friend After 40 #6 - HRT Is NOT One-Size-Fits-All #7 - Timing Matters #8 - Delivery Method Makes or Breaks Results #9 - BHRT Works Best When You Address the Big Five #10 - The Goal Isn't to Feel Younger, It's to Feel More Like YOU Midlife isn't the beginning of the end, it's a time of radical transition and ownership. Hormone replacement therapy is one of the biggest levers you have. Use it wisely.
Dr. Drew Pinsky goes scorched earth on what he calls California's “Homelessness Industrial Complex” - He breaks down exactly how California has built a billion-dollar machine designed to profit from bureaucracy... all while keeping addicts sick, untreated, and abandoned on city sidewalks. From corrupt NGO's to dirty politicians and woke ideology - nothing is left unexposed. Then we get into the political brawl between Halle Berry and Gavin Newsom—why the Governor vetoed the ‘Menopause Care Equity Act' twice, and why denying the life-changing benefits of HRT to men and women in mid-life isn't just bad politics... it's a medical travesty.And finally, he tears into the exploding controversy around Kennedy's decision to remove the Hep B vaccine from the CDC's childhood vaccine schedule as well as whispered conversations about a potential ‘Black Box Warning' on COVID shots for our kids and teens.
>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey. https://modernendocrinewellness.com/join-gut-health
For more info on how I can help you, visit my site BetterByDrBrooke.I've long shared my grievances about testosterone pellets, but as always, I want to give you a balanced and fair take on all things women's hormones. In this episode, I cover some advantages to pellets (there are a few!) as well as going into more detail on the downsides, including some irreversible side effects. As mentioned in the episode, if you missed the emails about our annual GRATITUDE sale, with 15% off our supplements, email Jess at admin@betterbydrbrooke.com. Resources mentioned in this episode: Article Pros & Cons of Pellet Therapy For Women Dr Brooke Show #446 What Women Need To Know About Testosterone HRT Dr Brooke Show #444 Should You Be Cycling Your HRT? Grab the Midlife Is More Than HRT guide free right here if, like me, midlife didn't feel quite like you expected. And be sure to listen to episodes #438 and #439, which were all about the mess that midlife can be, and my 3G + 4R process to tackle it! Stuff I Know You Will Love If you are looking for an expert prescriber for HRT during your perimenopause or menopause journey but are at odds with your local provider being a bit behind current best practices or you simply can't find anyone near you to help, it is MIDI to the rescue! I've worked with a number of telehealth services in my search for providers that are up to date on modern menopause medicine, have great customer service, and are licensed in all 50 states and I'm so thrilled to have found my provider with MIDI. If you too need help with getting HRT please use this link bit.ly/drbrookemidi to try MIDI with no membership fees and insurance billing available. Be sure you connect with me in my FREE PRIVATE Facebook group: Hormones & Happiness with Dr. Brooke where other amazing, like-minded women like YOU are already hanging out! Join us! Follow Dr. Brooke on Instagram and get signed up for my awesome emails here. Seriously, I write really great emails, or so 1000s of women tell me and I'd like to send you one too. To work with Dr. Brooke click here and if you loved this episode please leave a review!
In this episode of the Living Well podcast, host Liv Heal and guest Lyndi Mullinax delve into the complexities of hormone replacement therapy (HRT), discussing its benefits, misconceptions, and the importance of proper medical guidance. They explore the cultural shift in attitudes towards HRT, the significance of understanding hormone levels, and the role of nutrition and lifestyle in hormone health. The conversation emphasizes the need for personalized care and informed decision-making when considering HRT. In this conversation, Liv and Lyndi discuss the complexities of hormone replacement therapy (HRT), focusing on testosterone and progesterone for women. They emphasize the importance of understanding hormone levels, advocating for oneself in healthcare, and the need for comprehensive assessments before starting any treatment. The discussion also highlights the significance of lifestyle changes in conjunction with hormone therapy and announces an upcoming summit aimed at empowering women to prioritize their health and well-being.
A lot of research is going into hormone replacement therapies, and it's about time...us 40+ women are THE LARGEST group on the planet, and we are being marketed to like crazy....not all products or offerings are good for us!Here, I break down some of the latest research to help clarify the differences between the apparent 'more natural' bio identicals and it's sister, synthetic HRT. To download this transcript, look in the comments below. Book a complimentary Body Breakthrough strategy call with Karen and move into YOUR Best Body and Life beyond 40! www.warriorwomanfitness.com/apply
As we know, menopause is not a downfall, it's a metamorphosis, and Petra Coveney—former BBC journalist, founder of Menopause Yoga, bestselling author, and unapologetic menopause rebel—joined Sally to tear down every stale narrative about “the change.”And trust us… this conversation goes there.Petra went through perimenopause early, alone, confused, and dismissed by doctors who had nothing to offer her except a pat on the head and a “good luck.”The frustration, shame and rage… she tapped into all of it. And what came out of that fire?Menopause Yoga—the world's first specialist yoga program built to support the physical, emotional, and psychological rollercoaster of perimenopause through second spring.In this episode, Petra breaks down:
‣ Book Your COMPLEMENTARY CONSULATION and CALORIE CALCULATION call:- how much & what to eat
Welcome to Real Food Recovery, a podcast created by two lifelong processed food addicts with over 100 years of addiction (and recovery) between them. Paige Alexander and Jamie Morgan Reno use their Real Food Recovery podcast and social media channels to share their struggles, lessons learned, tools, tips, and resources that freed them from decades of food addiction, obsession, and loss. Join us as we welcome Anja Hall, a chef, wellness entrepreneur, and metabolic health advocate who has built four successful companies centered on cooking, high-quality food, and health. She is the co-founder of The Blood Sugar Method, a program designed to help individuals improve their blood sugar and metabolic health through holistic, long-term practices, particularly in cases involving PCOS, menopause, pregnancy, GLP-1 use, and HRT. A longtime chef for the Golden State Warriors, Cleveland Cavaliers, and other professional athletes, Anja knows firsthand how food fuels performance and longevity. She has also competed—and won twice —on the Food Network, proving that nutritious eating can be both gourmet and delicious. You can find Anja at www.thebloodsugarmethod.com. In every Real Food Recovery episode, Paige and Jamie take time to answer viewer questions about processed food addiction, obsession, and recovery. Be sure to submit yours on their YouTube Channel or Facebook Page. You can also follow Real Food Recovery on Instagram (@realfoodrecovery4u), TikTok (@realfoodrecovery) or at www.realfoodrecovery4u.com.
At the 2025 San Antonio Breast Cancer Symposium (SABCS), Dr. Tara Sanft, associate professor of medicine at the Yale School of Medicine and director of the Yale Survivorship Clinic, moderated a session called “Balancing Act: Hormone Replacement Therapy in Breast Cancer Care.” Listen to the episode to hear Dr. Sanft explain: the difference between systemic and local HRT why HRT decisions need to be nuanced and individualized for anyone with a history of breast cancer – there is no one-size-fits-all her advice to people with a history of breast cancer who are considering HRT
After 20 years of prescribing hormone replacement therapy to tens of thousands of patients, both in her clinic and through her telemedicine company Menrva, I have identified the critical gaps in how HRT is being prescribed, monitored, and optimized across the United States. This isn't about "should you" do hormones. This is about how to do them right. In this episode,I break down the 10 non-negotiables you need to know if you're considering HRT, currently on HRT, or feeling like your current protocol isn't working. From the biochemistry of bioidentical vs. synthetic hormones to why your gut health determines how well your estrogen gets metabolized, this is the master class your doctor should have given you, but didn't. We're talking about natural bioidentical hormones, the truth behind the Women's Health Initiative (spoiler: it was about Premarin and synthetic progestins, NOT bioidentical estrogen), and how to use precision medicine to guide YOUR hormone replacement therapy, not a one-size-fits-all protocol that leaves 50% of women undertreated and 25% overtreated. Discover The 10 Non-negotiables: #1 - Bioidentical Is NOT a Buzzword #2 - Your Symptoms Are Metabolic Signals #3 - The WHI Study Was About Premarin & Provera #4 - Your Gut & Estrogen Are in Constant Conversation #5 - Testosterone Is a Woman's Friend After 40 #6 - HRT Is NOT One-Size-Fits-All #7 - Timing Matters #8 - Delivery Method Makes or Breaks Results #9 - BHRT Works Best When You Address the Big Five #10 - The Goal Isn't to Feel Younger, It's to Feel More Like YOU Midlife isn't the beginning of the end, it's a time of radical transition and ownership. Hormone replacement therapy is one of the biggest levers you have. Use it wisely.
In Episode 2 of this deep-dive hormone series, Dr. Brendan McCarthy—Chief Medical Officer of Protea Medical Center in Tempe, AZ—breaks down the part of progesterone almost no one talks about: its powerful role as a brain hormone. Most women are only taught that progesterone is about fertility and uterine lining. But the truth? Progesterone is a neurosteroid that influences your amygdala, hippocampus, and prefrontal cortex—three key brain regions that shape your stress response, emotional stability, sleep, memory, and self-trust. This episode covers: ✔️ Why perimenopause makes your brain feel “out of control” ✔️ The link between progesterone decline and anxiety, irritability, depression, night sweats, and brain fog ✔️ How progesterone converts to allopregnanolone (your brain's natural calming signal) ✔️ Why women under chronic stress or in their late 30s–40s feel symptoms more intensely ✔️ How hormonal imbalance impacts memory, decision-making, and emotional regulation ✔️ Why you're not broken—and what real validation and proper care looks like Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.
In today's episode, I'm opening up about something I've never fully shared before — my own thyroid journey. Even as a practitioner, I'm not immune to the hormonal shifts, viral triggers, and autoimmune quirks that so many midlife women face. My goal with this episode is to pull back the curtain, remove the shame, and give you a deeper understanding of what can really drive thyroid issues in perimenopause and menopause. I walk you through the symptoms I experienced, what my lab work revealed, how my antibodies suddenly spiked, and the surprising reason why (hint: it wasn't gluten or leaky gut). I also share how I'm supporting my thyroid now, including why I chose Low Dose Naltrexone (LDN) and how modern medicine + holistic strategies can work beautifully together. Whether you've been diagnosed with Hashimoto's, you suspect thyroid changes, or you've simply "never felt the same" since getting sick — this episode will give you clarity, validation, and a roadmap for next steps. In This Episode, We Cover: 1. Practitioners Aren't Superhuman (and Why I'm Sharing My Story) 2. My Personal Symptoms 3. The Rollercoaster of Thyroid Health 4. What Actually Triggered My Antibodies 5. How I'm Addressing Thyroid Autoimmunity 6. Hashimoto's vs. Hypothyroidism – Clearing Up the Confusion 7. Genetics, Gut Health & The Importance of Testing 8. When & Why To Check Your Thyroid Mentioned in this episode: EQUIP PRIME PROTEIN – Click HERE to grab yours and use my code: TARA to get 15% off. When you sign up for a subscription via my link, you'll save 30% on the first month & 15% on any subsequent months! HERBATONIN - Click HERE to visit the shop. Save 10% when you use Tara's code: Tara10 PIQUE TEA – These are some of Tara's favourite teas! They're crystal form, which makes them super unique and easy to transport in your purse, (they come in single use satchels!) and higher in polyphenols. They're made from high quality ingredients with triple toxin screening, (super important when it comes to your tea). Click HERE to visit the shop. HRT Made Simple™ - Learn how to confidently speak to your doctor about the benefits of hormone replacement therapy so you can set yourself up for symptom-free, unmedicated years to come without feeling confused, dismissed, or leaving the medical office minus your HRT script. Hair Loss Solutions Made Simple™ – This course will teach you the best natural, highly effective, and safe solutions for your hair loss so you can stop it, reverse it, and regrow healthy hair without turning to medications. The Perimenopause Solution™ – My signature 6-month comprehensive hormonal health program for women in midlife who want to get solid answers to their hormonal health issues once and for all so they can kick the weight gain, moodiness, gut problems, skin issues, period problems, fatigue, overwhelm, insomnia, hair/eyebrow loss, and other symptoms in order to get back to the woman they once were. [FREE] The Ultimate Midlife Perimenopause Handbook - Grab my free guide and RECLAIM your confidence, your mood, your waistline and energy without turning to medications or restrictive diets (or spending a fortune on testing you don't need!). [BOOK A 30-MINUTE SESSION WITH TARA HERE]
Learn how natural, whole-person approaches can transform menopause without HRT in this info-packed discussion. From phytoestrogens and omega-3s to mindfulness and exercise, discover practical steps to manage symptoms naturally and thrive during this life transition.For more on this topic, visit https://bettyjohansen.com/2024/04/18/stepping-into-your-best-years-a-guide-to-dancing-through-menopause/ Wordsmith World City: Big Spring Address: Texas Website: https://bettyjohansen.com/
Beth Zupec-Kania is a leading global expert in ketogenic therapy, known for her decades of clinical experience and clear, compassionate guidance. A registered and certified dietitian-nutritionist, she has spent more than 30 years helping clinicians, patients, and families use therapeutic ketosis safely and effectively for neurological, psychiatric, metabolic, and even select cancer-related conditions. In this episode, Dr. Tro, Dr. Brian, and Beth talk about… (00:00) Intro (02:23) What The Charlie Foundation is and how Beth first became involved (05:09) The frustrations Beth faced as a nutritionist promoting an, at the time, very taboo diet in the ketogenic diet (09:37) How Beth initially came to see the power of keto as a therapy for people with epilepsy (12:16) The evolution of the keto diet over the decades (18:40) How the keto diet can be life changing for children with epilepsy (27:28) Epilepsy patients weaning off of the keto diet (30:22) Why a supplemental or drug cannot replace the keto diet for epilepsy patients (32:44) How sugar and the microbiome play into epilepsy and seizure disorders (41:28) Beth's personal experience with the ketogenic diet (47:38) HRT, women's health, and the keto diet (51:54) Addiction and denial (56:55) Fatty liver disease and the keto diet (01:00:02) The new dietary guidelines (01:04:04) Eating REAL fats (01:05:52) For more information, please see the links below. Thank you for listening! Links: Please consider supporting us on Patreon: https://www.lowcarbmd.com/ Beth Zupec-Kania: The Charlie Foundation: https://charliefoundation.org/ Website: https://www.bethzupeckania.com/ Keto Mastery: https://www.ketomastery.pro/ Dr. Brian Lenzkes: Website: https://arizonametabolichealth.com/ Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author Dr. Tro Kalayjian: Website: https://www.doctortro.com/ Twitter: https://twitter.com/DoctorTro IG: https://www.instagram.com/doctortro/ Toward Health App Join a growing community of individuals who are improving their metabolic health; together. Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more. Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888 Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US Learn more: https://doctortro.com/community/
Today, I'm giving you a full roadmap of non-hormonal symptom relief, built from research and real-world experience. We'll cover why some women can't or don't take HRT, why some still struggle even when they do, and what tools you can use whether you're hormone-free, hormone-curious, or hormonally supplemented but still not completely supported. Then we'll go symptom by symptom including hot flashes, sleep, anxiety, metabolism, joint pain, GSM and map out what actually works. We Cover: • Why some women avoid HRT and why others still need more support. • The foundations every woman needs, with or without hormones. • Non-hormonal solutions for hot flashes, night sweats, anxiety, irritability, sleep, mood, metabolism, muscle loss, cognitive decline, weight gain, fatigue and GSM. • What to know about supplement safety and phytoestrogens. RESOURCES Recommended Items + Discounts: Karen Martel: https://podcasts.apple.com/us/podcast/non-hormonal-solutions-to-peri-and-post-menopausal/id1438772276?i=1000682224707 Herbal Medicine in Menopause: Myths, Mistakes, & Must-Haves with Sara Chana Silverstein Master Herbalist: https://podcasts.apple.com/us/podcast/herbal-medicine-in-menopause-myths-mistakes-must-haves/id1531105768?i=1000727879524 Discount Codes PDF: Osteoarthritis episode: https://youtu.be/b7aTb7cHn7o?si=WDVXmO3HwHruhXmm PRP episode: https://podcasts.apple.com/us/podcast/stop-arthritis-prevent-degeneration-in-joints-alternatives/id1531105768?i=1000523184934 https://drive.google.com/file/d/110eG0zBhHwpWS6_BVgj1RtL-JmKgqgmL/view?usp=sharing Urolithin A: https://youtu.be/OsaWrkM3Fxs?si=SeZ-nTuf46H2o4QO Methylene Blue: https://youtu.be/XHhMN3oC69M?si=B5pCINSXA19rNcQs BFR guide: https://drive.google.com/file/d/1dSwrG6u737O5o7_TOd3PkRfeGsz8ESX5/view?usp=drive_link Hot Flash Program: https://hackmyage.com/hot-flash-masterclass/ Energy Reboot Program: https://hackmyage.com/energy-reboot-self-guided/ Give thanks to our sponsors: Try Vitali skincare. 20% off with code ZORA here - https://vitaliskincare.com Get Primeadine spermidine by Oxford Healthspan. 15% discount with code ZORA here - http://oxfordhealthspan.com/discount/ZORA Get Mitopure Urolithin A by Timeline. 20% discount with code ZORA at https://timeline.com/zora Try Suji to improve muscle 10% off with code ZORA at TrySuji.com - https://trysuji.com Try OneSkin skincare with code ZORA for 15% off https://oneskin.pxf.io/c/3974954/2885171/31050 Join the Hack My Age community on: YouTube: https://youtube.com/@hackmyage Facebook Page: @Hack My Age Facebook Group: @Biohacking Menopause Biohacking Menopause Private Women's Only Support Group: https://hackmyage.com/biohacking-menopause-membership/ Instagram: @HackMyAge Website: HackMyAge.com For partnership inquiries: https://www.category3.ca/ Some episodes of Hack My Age are supported by partners whose products or services may be discussed during the show. The host may receive compensation or earn a minor commission if you purchase through affiliate links at no extra cost to you. All opinions shared are those of the host and guests, based on personal experience and research, and do not necessarily represent the views of any sponsor. Sponsorships do not imply medical endorsement or approval by any healthcare provider featured on this podcast.
Coach and educator Carla Wainwright joins Dr. Gillian in episode 238 to reframe midlife (about 40–65) as a gateway rather than a decline. Drawing on science and somatic wisdom, Carla explains how shifting sex hormones affect metabolism, sleep, stress tolerance, and body composition—and why nervous‑system regulation, metabolic basics, and pleasure practices are foundational for healthspan. You'll learn simple micro‑resets (breath, grounding, nature time), how to stack small rituals, and why cultivating daily moments of joy/connection boosts oxytocin and nitric oxide—two chemistry cues that counter cortisol, support repair, and enhance mitochondrial and brain function. The conversation also touches on individualized choices around HRT, sleep strategies, and the power of community, movement, and mindful communication at any age. Practical, compassionate, and doable. Carla has an MSc in Conservation Biology, a four‑year diploma in Heilkunst/homeopathy, certifications in sex, love & relationship coaching, and >25 years as a senior yoga instructor/trainer. TimeLine: 00:00 — Welcome; why embodiment matters for aging youthfully 02:15 — Carla's path; reframing midlife as a gateway 07:16 — "Heilkunst": Hahnemann's broader system beyond homeopathy 08:21 — Perimenopause/menopause biology: hormones, metabolism & stress 11:14 — Sleep & HRT discussion; lifestyle + hormones, not either/or 13:18 — Healthy aging basics: sleep, movement, food, community, presence 14:15 — Nervous‑system regulation: breath, grounding, nature micro‑resets 18:02 — Daily titration of safety; hugs, pets, connection, barefoot forest time 22:24 — Pleasure as longevity lever; oxytocin & nitric oxide explained 25:00 — Five pleasure moments/day; reflective recap to reinforce benefits 30:00 — Three powerful daily choices for fog/fatigue/disconnection 33:09 — Dance, joy & community; one mindset shift for the week 33:49 — Close & calls to action Learn about Carla Wainwright: Free Gift - Your Vibrancy Guide: https://vibrancyguide.com/ Instagram: https://www.instagram.com/carlawainwright/ Facebook: https://www.facebook.com/CarlaWainwrightCreatrix/ Connect with Dr. Gillian Lockitch Download your Gift: Ten Tips for Building A Better body: Better Bones, Muscles and Joints Guide to Nature's Colourful Antioxidants. Book a one-on-one call with Dr. Gillian Lockitch Join the Growing Older Living Younger Community
This interview took place on a historic day: the FDA removed the black box warning for HRT (hormone replacement therapy) after 20 years. My guest, Dr. Mariza Snyder, author of The Perimenopause Revolution, explains why this matters and why women have been suffering needlessly for decades while doctors dismissed their symptoms as "just aging" or "just stress." Perimenopause is the 4 to 10-year transition where hormones wildly fluctuate before menopause, and Dr. Snyder calls it "the window of vulnerability." She uses a powerful metaphor: imagine estrogen as your brain's master CEO who shows up like clockwork from 9 AM to 6 PM for 30 years. Then, suddenly, without warning, it shows up at 2 PM one day and leaves at 11 PM, then shows up at 6 AM the next day and leaves at 11 AM. Your brain scrambles trying to regulate energy, neurotransmitters, sleep, mood, and cravings. The most compelling insight of our conversation is a Mayo Clinic study that found 84% of menopausal women don't seek care. Why? Because they feel judged in the doctor's office. Dr. Snyder wrote her book as the roadmap she desperately needed when she started her own perimenopause journey, connecting symptoms to future health outcomes and providing practical solutions beyond just "you're getting older."
November News You Can Use Federal Rules and Hot Flashes (Loans, Hormones, Measles) Topics include: New federal rule absurdly declassifies advanced nursing and therapy degrees as “professional,” worsening medical education costs Meanwhile capping physician loans below actual med-school debt which risks ensuring future physicians disproportionately come from wealthy families The long-misleading black-box warning on HRT has finally been removed, restoring access to a beneficial therapy The hype around new non-hormonal alternatives for Menopause likely not going to bring an impact Measles is resurging as vaccination rates drop CMS releases new labyrinthine OPPS/ASC rules—including phasing out the Inpatient-Only rule by 2028 Healthcare tech continues to flag patient risks without offering meaningful action, proving that data without direction is worthless. To stream our Station live 24/7 visit www.HealthcareNOWRadio.com or ask your Smart Device to “….Play Healthcare NOW Radio”. Find all of our network podcasts on your favorite podcast platforms and be sure to subscribe and like us. Learn more at www.healthcarenowradio.com/listen
Hormones start shifting way earlier than anyone tells us, and for most women over 35 that sneaky change can make you feel like you are aging in fast-forward. This episode breaks down the hormone symptoms most doctors overlook and explains what is actually happening with estrogen, progesterone, and testosterone when you suddenly have brain fog, mood swings, stubborn weight gain, low libido, or sleep that goes off a cliff. Chalene also clears up the outdated fears around hormone therapy and shares the updated science every woman needs, plus simple natural hormone support options if HRT is not your thing. And if you have ever felt dismissed or confused by conflicting advice, you will hear exactly how to find a clinician who actually understands women's hormone health so you can age powerfully instead of feeling unlike yourself. Watch this episode on YouTube this Sunday!!
In this episode of The SavvyCast, I'm joined by my dear friend and fellow midlife influencer Deanna Pizitz of Well and Worthy Life for a candid, girl-talk Q&A. I asked my Instagram community to submit their burning questions, and today we're diving into all of them—from marriage and midlife transitions to plastic surgery, hormones, adult children, and more. This is truly a fun, honest, and real-life conversation between two midlife women who have lived a lot, learned a lot, and love sharing what's worked (and what hasn't). EPISODE HIGHLIGHTS: Deanna's journey through two past marriages and how she navigated divorce Insights into her current marriage and what she's learned along the way How to navigate the transition of children growing up, getting married, and having babies Tips for dividing time with adult children and in-laws during the holidays Meaningful and practical gift ideas for in-laws An open conversation about plastic surgery: Jamie's endoscopic facelift, CO2 laser, and mommy makeover with breast reduction Deanna's breast augmentation, mini tummy tuck, and deep plane facelift Daxify vs. Botox: how they differ and what to know Hormone replacement therapy (HRT) and why both Jamie and Deanna stopped testosterone pellets WHO IS DEANNA PIZITZ OF WELL & WORTHY LIFE? Deanna is a Certified Integrative Nutrition Health Coach and Life Coach who specializes in supporting midlife women. She is also a blogger and podcaster, and the founder of Well and Worthy Life, a Southern-based style and wellness company in Birmingham dedicated to inspiring women through empowering lifestyle and wellness content. Her mission is to reach women, whether in Birmingham or beyond, who are looking for meaningful, practical guidance on living a happier, more fulfilled midlife. Deanna brings a relatable, real-life perspective to her work, continually pursuing her own personal growth and encouraging her audience to do the same. LINKS & RESOURCES MENTIONED: Follow along with Deanna on Instagram @wellandworthylife Well & Worthy Life Website Well & Worthy Life Podcast: Overcoming the Shame of Divorce Listen on Apple Podcasts and Spotify WHERE TO LISTEN The SavvyCast is available on all podcasting platforms and YouTube. One of the best ways to support the show is by leaving a rating and review—I so appreciate you sharing your thoughts, my friends!
Roxy's Ride & Inspire RAWcast - Mountain Bike & Mindset Podcast
We dive into what's actually happening in peri- and postmenopause (hormonally, neurologically, and physically) and how those changes show up on the bike. From fear on technical trails, to fatigue, difficulties concentrating, to the “hit by a truck” recovery days… none of this is random. This episode is science-based and NOT only for women
▶︎▶︎Preorder my new book ‘The Connection Code': https://beehive.drmelissasonners.com/the-connection-code If you're in your 40s and have been feeling “off” lately: low energy, anxious for no clear reason, gaining weight around your middle, waking up at 3AM, or wondering why your sex drive suddenly disappeared — there's a powerful explanation hiding in your hormones. These symptoms are some of the most common early perimenopause signs, even in women who still have regular periods.In this episode, I sit down with women's hormone & menopause expert Dr. Mariza Snyder to break down the ONE midlife hormone shift that can silently disrupt your mood, metabolism, sleep, libido, stress tolerance, and sense of self. This neuroendocrine transition often starts in your late 30s or 40s, and understanding it is the key to feeling like yourself again.We talk about the hidden hormone changes most women don't realize they're experiencing, why so many women in midlife describe feeling “lost,” and what's actually driving symptoms like anxiety, brain fog, irritability, weight changes, low motivation, and emotional overwhelm.This season of life is an incredible opportunity to rebirth your energy, clarity, and purpose.What You'll Learn:The midlife hormone imbalance that affects mood, sleep, weight, and libidoEarly perimenopause symptoms women often missWhy so many women in their 40s feel disconnected or “not like themselves”The brain chemistry changes behind anxiety, irritability, and overwhelmThe identity “upgrade” that happens during hormonal shiftsExercise snacks for blood sugar, metabolism, and emotional regulationPleasure stacking & nervous system tools for daily stressLow libido in perimenopause — what's hormonal vs emotionalThe newest HRT research + FDA vaginal estrogen updateHow to rebuild community and connection during life transitionsResources:Dr. Mariza Snyder: https://drmariza.com/ Get her book ‘The Perimenopause Revolution: Reclaim Your Hormones, Metabolism & Energy': https://amzn.to/3FwSAlK Melissa's Red Light faves, with special codes and discounts: https://www.drmelissasonners.com/red-light-guide Be Inspired Mama Journal: https://amzn.to/4afbs3s Want a free and meaningful way to support the show? Give us a ⭐️⭐️⭐️⭐️⭐️ rating on Spotify or Apple Podcasts (you can even leave a review on Apple too!). And if you're tuning in on YouTube, don't forget to like, comment, and subscribe. Your support helps more mamas discover this space and we're so grateful you're here.
In today's episode, I'm opening the first chapter of what I believe is the most important series I've ever created — a deep dive into progesterone and why it became the heart of my medical practice. For more than 20 years, I've watched this “simple, humble hormone” transform women's lives in ways most conventional medicine overlooks. What started in two small treatment rooms has grown into a 25,000 sq ft facility, and the core of our success comes down to understanding progesterone's impact on the female brain, stress response, and emotional resilience. In this episode, I break down: Why progesterone is far more than a reproductive hormone How it regulates the female stress response (amygdala, hippocampus, prefrontal cortex) Why anxiety, insomnia, irritability, and emotional overwhelm often map directly to progesterone decline Why so many women feel “unraveled” in their 40s — and why it's not their fault The science behind oral vs. sublingual progesterone (and why I use troches) How conventional medicine often misses the root cause The importance of physicians showing their work, their data, and their citations The lived stories and clinical outcomes that changed how I practice medicine If you've ever felt dismissed, unseen, or told that your anxiety or mood changes are “just stress,” this episode is for you. This is the beginning of a 7-part series where I break down the neurobiology, endocrinology, testing, dosing, delivery methods, breast health, perimenopause, and more. Citations: Brinton, Roberta Diaz, et al. “Neurosteroids and Brain Function.” Steroids, vol. 81, 2014, pp. 61–78. Epperson, C. Neill, et al. “New Insights into Perimenopausal Depression: A Neuroendocrine Vulnerability Framework.” The Lancet Psychiatry, vol. 9, no. 2, 2022, pp. 110–118. Frye, Cheryl A. “Neurosteroids—Endogenous Modulators of GABA_A Receptors.” Pharmacology & Therapeutics, vol. 116, no. 1, 2007, pp. 58–76. Genazzani, Andrea R., et al. “Progesterone, Stress, and the Brain.” Human Reproduction Update, vol. 16, no. 6, 2010, pp. 641–655. Meeker, John D., et al. “Environmental Endocrine Disruptors: Their Effects on Human Reproduction and Development.” Reproductive Toxicology, vol. 25, 2008, pp. 1–7. Mellon, Stanley H. “Neurosteroid Regulation of Central Nervous System Development.” Pharmacology & Therapeutics, vol. 116, 2007, pp. 107–124. Mizrahi, Romy, et al. “The Role of Allopregnanolone in Stress, Mood, and Trauma.” Neurobiology of Stress, vol. 11, 2019, 100198. Paul, Steven M., and Graziano Pinna. “Allopregnanolone: From Molecular Pathways to Therapeutic Applications.” Current Opinion in Neurobiology, vol. 48, 2018, pp. 90–96. Pluchino, Nicoletta, et al. “Progesterone and Allopregnanolone: Effects on the Central Nervous System in the Luteal Phase and in Perimenopause.” Gynecological Endocrinology, vol. 36, no. 6, 2020, pp. 441–445. Rasgon, Natalie L., et al. “Perimenopausal Changes in the Brain and Mood: A Review.” Journal of Clinical Endocrinology and Metabolism, vol. 107, no. 4, 2022, pp. 1120–1134. Reddy, Doodipala Samba. “The Neurosteroid Allopregnanolone and GABA-A Receptor Modulation in Epilepsy and Mood Disorders.” Frontiers in Neuroscience, vol. 12, 2018, 933. Schiller, Crystal E., et al. “The Neuroendocrinology of Perimenopausal Depression.” Trends in Neurosciences, vol. 44, no. 2, 2021, pp. 119–135. Schumacher, Michael, et al. “Neuroprotective Effects of Progesterone and Its Metabolites.” Frontiers in Neuroendocrinology, vol. 33, 2012, pp. 415–439. Selye, Hans. “The General Adaptation Syndrome and the Diseases of Adaptation.” Journal of Clinical Endocrinology, vol. 6, no. 2, 1946, pp. 117–230. Sheng, Jun, and György Buzsáki. “Neuronal Firing and Theta Oscillations in the Amygdala During Fear Conditioning.” Neuron, vol. 53, 2007, pp. 653–667. Smith, Sheryl S. “Progesterone Withdrawal Increases Neuronal Excitability in the Hippocampus: A GABA_A Mechanism.” Journal of Neuroscience, vol. 28, 2008, pp. 10171–10179. Snyder, Jonathan S., et al. “Adult Hippocampal Neurogenesis and Stress Regulation.” Nature Reviews Neuroscience, vol. 12, 2011, pp. 1–9. Stanczyk, Frank Z., and Jerilynn C. Prior. “Progesterone and Progestins: A Review of Pharmacology, PK, and Clinical Use.” Steroids, vol. 82, 2014, pp. 1–8. Tu, Ming-Je, et al. “Oral, Vaginal, and Transdermal Progesterone: PK, Metabolism, and Tissue Distribution.” Drug Metabolism Reviews, vol. 52, no. 2, 2020, pp. 1–28. Wang, Jun, et al. “Stress, Amygdala Plasticity, and the Neuroendocrine Interface.” Nature Neuroscience, vol. 10, 2007, pp. 1093–1100. Weinstock, Marta. “The Hippocampus and Chronic Stress.” Neurochemical Research, vol. 42, 2017, pp. 1–12. World Health Organization. Progesterone and Reproductive Function: Clinical Perspectives. WHO, 2019. Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.
At my monthly Ask Me Anything Webinars, I always get questions about hormone therapy- when to start, when to stop, if the dose should be changed as women get older, and what to do if someone continues to have symptoms or continues to bleed… In this episode, Dr. Risa Kagan and I answer submitted questions. We start by briefly running through the established indications for starting menopausal hormone therapy (MHT), and then Dr. Kagan and I discuss the “what ifs” of hormone therapy. Do you have to wait for 12 months without a period before starting MHT? If someone is taking birth control pills for control of perimenopause symptoms, at what point should they go off? And can they immediately transition to MHT or do they need to take a break and make sure they are no longer making estrogen? A woman with severe hot flashes is having all day, all night hot flashes- how long is it going to take to get some relief? Does it matter if it is oral or transdermal as far as the onset of action? What are the chances of getting 100% relief? If someone has started MHT but is still having flashes, how long should they wait before adjusting it? What is the best starting dose if someone has severe flashes? High or low? A woman wrote in that she has been using a 0.75 patch, but continues to have severe flashes. She got a serum level, and it is 10. Her doctor is reluctant to increase her dose. What would you tell her? A woman has tried four different protocols and has nuisance bleeding with all. She had an ultrasound and biopsy, and it was all normal. She wants to continue MHT, but is tired of the bleeding. She wants to know which protocol is the least likely to cause bleeding An internist told a woman that after 5 years, it is time to go off her MHT. What about if she is primarily taking it for hot flashes- how likely is it that her hot flashes will return? What about if she is primarily on it for bone health (known osteopenia) and joint pain-? What about if she is primarily taking it for sexual benefits? (Libido, lubrication, orgasm) ? What about if she is primarily taking it because she is worried about dementia A woman decided to go off HT since she was only taking it for hot flashes and is now 10 years out. Her manicurist told her that she should taper; otherwise, her flashes will come back. Her gyne says, stop. What does Dr. Kagan say? A 60 year old woman started estrogen when she had a hysterectomy and ovary removal. She was told by her internist that there is no way she will still be having hot flashes in her 60s, and therefore no reason to continue her estrogen. Is that correct? What is the likelihood that she will still be having hot flashes in her 60s or 70s? The next question is from a woman who increased her oral estradiol to 2 mg to get rid of her flashes, but is still taking her original Prometrium dose 100 mg. Is that enough to protect the lining of her uterus? When do you increase it? A question from a Substack reader- “I used estradiol gel for 8 years at the start of menopause. I decided to stop it and did so for 3 years; however, my hot flashes (sleep, mood, etc) were relentless and violent. I decided to start again after a 3-years hiatus and at the age of 65. I feel so much better. Is this a problem having stopped and then started again a few years later?” How can you tell the effectiveness of the HRT you're taking (other than no more hot flashes?) I still feel lack of motivation, low libido, joint aches and I'm so much slower running (1 min+/mile). (What this really comes down to, is what are realistic expectations for what HT will do?) How long can a postmenopausal woman stay on testosterone, estrogen and Progesterone? Let's say a woman has been using a .05 estradiol patch but her skin is really irritated and has decided to try the spray instead. What is the equivalent dose? A woman with a hysterectomy who is taking estrogen alone has been taking a 1 mg estradiol pill. She has decided to switch to conjugated equine estrogen since she would like breast protection. Is that correct thinking? If she is going to make the switch, what is the equivalent dose? A 51 year old is no longer having hot flashes but wants to continue her transdermal estrogen since she has low bone mass and is worried about progression to osteoporosis. What is the minimum dose of estradiol to ensure that she is getting maximum bone protection? Many questions came in about initiating hormone therapy after age 65... Dr. Risa Kagan is a Clinical Professor in the Department of Obstetrics, Gynecology, and Reproductive Sciences at the University of California, San Francisco, and a consulting gynecologist with Sutter Health. Other episodes with Dr. Kagan Episode 114- Is Duovee the Ideal Hormone Therapy? Episode 175 Your Bones On and Off Estrogen When an IUD is Your Post Menopause Plan
In this week's episode Sophie and I discuss this week's events, including chaotic weekends with sick children, health updates on my cats, HRT update, bunions and Sophie nicking my shoes growing up. As well as preparations for Christmas. I also share all the inside gossip from my recent photo shoot, and how much I LOVES IT! They flew KIM KARDASHIN... make-up artist just for your truly. We chat about the current headlines, especially a supposed feud between me and a journalist. We also answer listener questions which I love, so keep sending them in guys. And reflecting on our family dynamics and personal growth as well as updates on mum. ENJOY! Learn more about your ad choices. Visit megaphone.fm/adchoices
There is so much misinformation when it comes to health and beauty advice aimed at women over 40. Today, Jennifer Hanway and I talk about what truly helps during perimenopause and menopause, the traps of misinformation on social media, and the foundations for your skin, energy, and longevity. Jennifer shares lab-first steps, when HRT and peptides belong in your plan, and how to get the most from expensive medical aesthetic treatments like Sculptra. Tune in, take notes, and get ready to swap hype for habit. Check out our Sponsors: Shopify - Start your $1/month trial at Shopify.com/happy SKIMS - The SKIMS Holiday Shop is now open at SKIMS.com. Let them know we sent you by choosing Earn Your Happy podcast in the dropdown after you purchase. Brevo - Head to brevo.com/earn and use the code EARN to get 50% off Starter and Business Plans for the first 3 months of an annual subscription. Aura Frames - save on the perfect gift at AuraFrames.com - get $35 off Aura's best-selling Carver Mat frames with promo code EARN at checkout. Northwest Registered Agent - Build your complete business identity in just 10 clicks and 10 minutes. Visit www.northwestregisteredagent.com/paidearn Blinds dot com - The Black Friday deals at Blinds.com are going strong all month long! Save $50 off when you spend $500 or more - use code EARN at checkout. HIGHLIGHTS 00:00 Why we're so informed and yet massively misinformed. 06:15 What makes misinformation so convincing on social platforms. 10:00 When is hormone replacement therapy appropriate? 13:00 What our moms never got told about menopause. 17:30 How affluent women can stop chasing trends. 25:00 The danger of copying someone else's diet when it wasn't built for your biology. 30:45 Is high protein bad for you? 35:30 What dermatologists won't tell you about topical skincare and internal skincare. 41:45 How nutrition and gut health amplify your aesthetic procedures. 45:00 The diet and supplements that make fillers last longer. 51:45 What's the longevity formula for younger skin from the inside out? 56:15 The habits that help or harm your skin microbiome. RESOURCES Learn more about Jennifer Hanway HERE Join the Audacity Challenge HERE! Join the most supportive mastermind on the internet HERE! Check out our FREE 90-Day Business Blueprint HERE! Listen to my free SECRET PODCASTS SERIES - Operation: Rekindle This B*tch Get glōci HERE Use code: HAPPY at checkout for 25% off! FOLLOW Follow me: @loriharder Follow glōci: @getgloci Follow Jennifer: @jenniferhanway
In this episode, Claudia sits down with Tonya Romano, Nutritional Therapy Practitioner and co-coach inside The Perimenopause Method, to talk about her personal journey into menopause - a few years earlier than expected. From losing her period in her 40s to discovering the power of functional testing, nutrition, weight training, and hormone therapy, Tonya's story will resonate with any woman wondering if what she's feeling is "normal." We covered: The early signs Tonya experienced that hinted something was off What it was like going through menopause in her 40s How her doctor didn't give any solution other than hormonal birth control How a functional approach to health helped improve her symptoms The mindset shifts and lifestyle changes that helped her feel like herself again How she navigated HRT and finding the right provider What she wishes more women did to prepare for menopause How her experience shapes her work with clients inside The Perimenopause Method CONNECT WITH TONYA: Website Instagram [ WATCH ON YOUTUBE ] BLACK FRIDAY SALE EXTENDED! Save $100 on a Perimenopause Clarity Session with me - a focused, personalized way to help you understand what's really going on in your body. Limited time only, limited spots, sale ends 12/15. Here's what's included: ✔ A personalized review of your health, one lab, and your symptoms ✔ Clear, customized next steps to start feeling better ASAP ✔ Opportunity to get your questions answered — without the overwhelm And because I know many women want answers now but plan to commit more deeply in the New Year, I'm adding a special bonus:
Being diagnosed with cancer is life-changing. But being told you have to stop HRT too? It's a double whammy that can leave you feeling lost, frightened, and unsure where to turn.In this episode, I speak with Sarah and Laura - two women who've lived through that moment. Laura is six months on, and Sarah is a year into life without HRT. They share their feelings on what it feels like, how they've coped, and what they've learned along the way.This conversation isn't about what's right or wrong - it is my hope that you will be able to reflect a little on what has happed to you, or learn how a loved one or patient may experience this double whammy of a situation.HRT can be transformative, even life-saving. So when it's suddenly taken away, the grief and worry are real. With over 2.3 million women diagnosed with breast cancer worldwide every year, thousands will face this same painful dilemma. And currently, there is ZERO support!I am so proud, that at Menopause and Cancer, we are the only organisation dedicated solely to supporting people through the menopause after cancer. Our mission is to make sure no one is left without options, guidance, or hope. Unsure where to start?Tune into podcast episode 178 - Stopping HRT: The Side Effect I Wasn't Ready For - with Dr TalaulikarAnd buy a copy of Dani's book Navigating Menopause After Cancer: https://amzn.eu/d/6Bw8zmTEpisode Highlights:00:00 Intro08:54 HRT Discussions After Breast Cancer17:39 Navigating HRT and Cancer Diagnosis25:19 Struggles with Cancer Treatment Decisions32:26 "Cancer, Menopause, and Recovery"42:11 "HRT Journey and Adjustments"47:42 "Ongoing Management of Menopause"54:10 Navigating Life Without HRT01:00:53 Support After Cancer JourneyConnect with us:For more information and resources visit our website: www.menopauseandcancer.org Or follow us on Instagram @menopause_and_cancerJoin our Facebook group: www.facebook.com/groups/menopauseandcancerchathub
The case for testosterone with Dr Kelly Casperson // joined again by the testosterone GOAT, Dr. Casperson breaks down how we think about testosterone and the differences between prescribing testosterone to men and women. Order My New Book: The Perimenopause Survival Guide: https://amzn.to/3SYALzehttps://amzn.to/3SYALzeJoin The Collaborative Medical Practice: https://thecollaborative.kit.com/11e9825fb5Enroll in my course on HRT management: https://heatherhirschmd.myflodesk.com/prescribehrtEnroll in the Practice Accelerator Course: https://the-menopause-course.teachable.com/p/acceleratorjuly2025
Fatigue in midlife isn't just about needing more sleep — it's often a sign that something deeper is out of balance. In this episode, Tara shares her clinical approach to fatigue, including how hormones, minerals, iron status, thyroid function, inflammation, gut health, and stress all impact your energy. She explains why basic labs don't always tell the full story and what to look for when fatigue doesn't improve with rest or supplements alone. You'll walk away with a clearer understanding of why you feel tired and what steps actually move the needle — plus how personalized testing and guidance can help you get your energy back for good. Here's what you'll discover in this episode: 1. Why "just getting older" isn't a reason to accept low energy Tara Thorne shares her refreshing perspective on why we shouldn't expect our bodies to bounce back like they did in our twenties, and how you can actually regain your spark at any age. 2. The importance of digging into your blood work Learn what labs to ask for (and why most doctors miss critical markers)—including a full-thyroid panel, specific immune markers, iron panels, and even markers for viral and bacterial infections. 3. How mineral imbalances could be sabotaging your energy Tara Thorne walks through the magic of HTMA tests and why simply popping magnesium or iron might not help (and could even make things worse!). 4. The gut-fatigue connection Surprise! You might not have GI symptoms and still have serious gut-driven exhaustion. Tara Thorne unpacks how gut health, inflammation, and "leaky gut" can zap your vitality. 5. The critical (but often overlooked) role of hormones and stress From optimizing your hormones with bioidentical HRT to managing stress and dialing in quality sleep, you'll get actionable advice to support your energy on every level. Other episodes of interest: EPS 114: Thyroid health in midlife: post-illness autoimmunity/hypothyroidism, why TSH will rise with iodine & this is OK, progesterone & thyroid health & more! EPS 129: Hypothyroidism goes undiagnosed all the time in midlife. This episode: everything you need to know to ensure this doesn't happen to you. EPS 123: Caution should be taken when supplementing vitamin D, iron & selenium. Do not DIY these supplements! EPS 130: Do not take oral / IV iron until you've listened to this. EPS 5: Copper Toxicity: How it may be driving your PMS, estrogen issues, OCD, anxiety & more. EPS 121: All-things-cortisol in perimenopause. Are levels usually high or low? Should we test cortisol? If so, how? Everything you need to know! Mentioned in this episode: HERBATONIN – Click HERE to visit the shop. Save 10% when you use Tara's code: Tara10 HRT Made Simple™ - Learn how to confidently speak to your doctor about the benefits of hormone replacement therapy so you can set yourself up for symptom-free, unmedicated years to come without feeling confused, dismissed, or leaving the medical office minus your HRT script. Hair Loss Solutions Made Simple™ – This course will teach you the best natural, highly effective, and safe solutions for your hair loss so you can stop it, reverse it, and regrow healthy hair without turning to medications. The Perimenopause Solution™ – My signature 6-month comprehensive hormonal health program for women in midlife who want to get solid answers to their hormonal health issues once and for all so they can kick the weight gain, moodiness, gut problems, skin issues, period problems, fatigue, overwhelm, insomnia, hair/eyebrow loss, and other symptoms in order to get back to the woman they once were. [FREE] The Ultimate Midlife Perimenopause Handbook - Grab my free guide and RECLAIM your confidence, your mood, your waistline and energy without turning to medications or restrictive diets (or spending a fortune on testing you don't need!). [BOOK A 30-MINUTE SESSION WITH TARA HERE]
Today's episode is a powerful, honest conversation with three incredible women who are taking their health into their own hands. Joined again by the brilliant Kimberly Cunningham, NP, we're talking about what it really looks like to reclaim your body, your confidence, and your joy after 40.Elizabeth, Andrea, and Orion share their deeply personal journeys with hormone replacement therapy and GLP-1/GIP weight-loss medications, what led them to seek help, what changed, what surprised them, and how their lives have transformed physically, mentally, and emotionally.This roundtable is honest, tender, eye-opening, and full of information that women are rarely given. If you've ever struggled with weight, mood swings, fatigue, food noise, or that feeling of “I don't recognize myself anymore,” this episode will feel like a breath of fresh air.Kimberly also breaks down the science behind GLP-1/GIP medications, HRT, PCOS, perimenopause, metabolic health, insurance barriers, and the stigma so many women carry, when the truth is, this is biology, not moral failure.This is the conversation I wish I had decades ago. And I hope it helps you feel seen, validated, and supported on your own path.Go to michellefox.com/podcast for full show notes. Hosted on Acast. See acast.com/privacy for more information.
This is a free preview of a paid episode. To hear more, visit sciencefictionspod.substack.comDoes the evidence support the use of hormone replacement therapy (HRT)? Depends on when you asked the question. At one point the consensus was “yes”; more recently it reversed. But should it have?It also depends on what symptoms you're talking about. Is HRT just all about hot flushes, or can it also treat mood and cognitive problems too? In this paid-only episode, we look at the evidence.To listen to the full episode and read the show notes, please become a paid subscriber to the Science Fictions podcast.
View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Carole Hooven is a human evolutionary biologist whose research centers on testosterone, sex differences, and behavior. In this episode, she explores how prenatal testosterone orchestrates male development in the body and brain, how early hormonal surges shape lifelong behavioral tendencies, and what rare natural experiments—such as 5-alpha-reductase deficiency—reveal about the biology of sex differentiation. She discusses distinct male and female aggression styles through an evolutionary lens, how modern environments interact with ancient competitive drives, and the implications of attempting to suppress them. The conversation also covers testosterone across the lifespan, the role of hormone therapy in both men and women, and Carole's own experience after surgical menopause, culminating in a broader discussion of masculinity, cultural narratives, and the consequences of denying biological sex differences. We discuss: How Carole became interested in exploring the biological and evolutionary roots of sex differences and the role of testosterone [2:30]; How testosterone and other hormones influence sex differences in aggression and behavior across species [9:45]; How chromosomes, the SRY gene, and early hormones direct embryonic sexual differentiation [12:15]; A stark contrast of male social bonding compared to females, and evolutionary parallels in chimpanzees [19:30]; How hormones like DHT shape sexual differentiation, and how 5⍺-reductase deficiency reveals the distinct roles of these hormones [22:45]; How sex chromosomes and prenatal testosterone shape early brain development and explain sex differences in childhood behavior [31:30]; How gamete differences shape reproductive strategies, energetic costs, and sex-specific behavior [42:30]; How evolutionary biology shapes sex differences in play, aggression, and conflict resolution (and how modern environments and cultural messaging can disrupt those patterns) [49:00]; Why males commit disproportionately more violent crime, and how cultural and environmental forces shape aggression [1:01:00]; Why females evolved different behavioral strategies: nurturing, risk aversion, and the cultural norms that override biology [1:04:00]; Whether male aggression is still necessary in modern society, why the underlying biological drives persist, and how modern society redirects these drives [1:06:30]; How testosterone levels naturally shift to support fatherhood and caregiving [1:13:30]; How testosterone shapes male mating strategies, and why long-term pair-bonding persists even when reproduction is no longer at stake [1:18:30]; The distinct roles of estrogen in male development, mood, libido, and muscle [1:25:00]; How evolution, health, lifestyle, and androgen receptor biology shape modern testosterone replacement therapy (TRT) [1:34:15]; Carole's experience with hormone replacement therapy (HRT), and the risks associated with TRT in younger men [1:45:15]; How Carole rebuilt after controversy: leaving academia and recommitting to scientific honesty [1:51:30,]; Carole's next book: examining masculinity, cultural narratives, and the cost of denying biological sex differences [1:57:30]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube
Dr Stacy Sims, expert in female physiology and training, collaborates with fx Ambassador Lisa Costa-Bir to discuss the intricate relationship between hormones and physical performance. Together they explore how the female hormonal cycle introduces unique challenges and opportunities. The follicular phase is the time when women typically excel physically, while the ovulatory phase can bring variations in how one feels during exercise. The mid-luteal phase can be challenging for high-intensity training, and the days leading up to menstruation require tailored adjustments due to mood, heart rate, and performance changes. Tailored exercise strategies are discussed, with tips for conditions like endometriosis and PCOS. Maintaining muscle mass during peri/menopause through specific exercise approaches is emphasised. Hormone Replacement Therapy (HRT) is clarified as not reversing aging but preserving lean muscle mass through exercise. The podcast also covers injury prevention, nutrition, and hydration strategies, offering women and clinicians an holistic guide to optimise their fitness journey throughout life. COVERED IN THIS EPISODE (00:27) Welcoming Dr. Stacy Sims (01:57) Phases of the menstrual cycle impacting energy and exercise (08:15) How anovulatory cycles are affected in training (09:41) Endometriosis and cold water immersion (11:28) Heat exposure for adaptive stress in autoimmune and inflammatory diseases (13:14) Training during Menopause and Perimenopause (18:56) HRT (21:37) Prevalence of injury in Perimenopause (24:15) Cycling exercise throughout the menstrual cycle (27:25) Protein in hormonal production (31:16) Fasting in Perimenopause (33:35) Carbohydrates for training (36:23) True hydration (38:45) Nutritional supplements for training performance (43:51) Adaptogenic herbs for training performance (45:45) Thanking Stacy and closing remarks Find today's transcript and show notes here: https://www.bioceuticals.com.au/education/podcasts/exercise-training-the-influence-of-female-sex-hormones-with-lisa-costa-bir-dr-stacy-sims Sign up for our monthly newsletter for the latest exclusive clinical tools, articles, and infographics: www.bioceuticals.com.au/signup/ DISCLAIMER: The information provided on fx Medicine by BioCeuticals is for educational and informational purposes only. The information provided is not, nor is it intended to be, a substitute for professional advice or care. Please seek the advice of a qualified health care professional in the event something you learn here raises questions or concerns regarding your health.
Layla and Kathy discuss horny women in their forties, HRT, slow fucking, dry humping and more. Tune in to hear all the details including how women in their forties are hornier than ever and why, how and why pellets are a game changer when it comes to sex drive, how peri-menopause is a woman's ovaries hurrah and how that plays into why women are so horny during that time, how and why you don't need to lose your sex drive after menopause, HRT and sex drive after menopause, how to get your sex drive back without hormones, the O Shot and what it does to your orgasms, slow fucks and why they're so good, the halfway in game and why you should try it one day, Kathy's experience of pellets, hormones during perimenopause and injections and which one she prefers, losing muscle tone and what to do to get it back plus a whole lot more. You can find Layla here: https://www.thecuriousgirldiaries.com To see HOT pics of my female guests + hear anonymous confessions + get all the episodes early and AD FREE, join my Patreon! It's only $7 a month and you can cancel at any time. You can sign up here: https://www.patreon.com/StrictlyAnonymousPodcast and when you join, I'll throw in a complimentary link to my private Discord! MY BOOK IS NOW OUT FOR PRE-ORDER!!!! Strictly Anonymous Confessions: Secret Sex Lives of Total Strangers. A bunch of short, super sexy, TRUE stories. GET YOUR COPY NOW: https://amzn.to/4i7hBCd To join SDC and get a FREE Trial! click here: https://www.sdc.com/?ref=37712 or go to SDC.com and use my code 37712 Want to be on the show? Email me at strictlyanonymouspodcast@gmail.com or go to http://www.strictlyanonymouspodcast.com and click on "Be on the Show." Want to confess while remaining anonymous? Call the CONFESSIONS hotline at 347-420-3579. All voices are changed. Sponsors: https://motorbunny.com/strictly — Black Friday Sale PLUS $50 off! https://butterwellness.com/ — Use the code STRICTLY at checkout for 30% OFF your entire order https://vb.health — To get 10% off LOAD Boost by VB Health use code: STRICTLY https://www.quince.com/strictlyanon — For premium quality Quince clothing plus FREE shipping and 365 day returns! https://bluechew.com — Get your first month of the new Bluechew Max FREE! Use code: STRICTLYANON https://brooklynbedding.com — Use my promo code STRICTLY at checkout to get 30% off sitewide https://beducate.me/pd2536-anonymous — Use code ANONYMOUS69 to get 50% off your yearly pass plus a 14-day money-back guarantee https://uberlube.com/discount/Strictly — Use code STRICTLY for 10% off Uberlube aka the BEST Lube EVER Follow me! Instagram https://www.instagram.com/strictanonymous/ X https://twitter.com/strictanonymous?lang=en Website http://www.strictlyanonymouspodcast.com/ Everything else: https://linktr.ee/Strictlyanonymouspodcast Learn more about your ad choices. Visit megaphone.fm/adchoices
Ready to go beyond standard cholesterol panels and track what actually matters? Get your comprehensive performance bloodwork analysis at witsandweights.com/bloodwork (code VITALITY20 for 20% off)—What if your blood work is missing the markers that truly predict long-term cardiovascular health? Can you build muscle, lose fat, and stay strong after 40 without risking your heart? And which biomarkers, hormones, and peptides actually move the needle for longevity and performance?I bring on Integrative Medicine & Cardiology Physician Dr. Abid Husain into the conversation, and we get into the evidence behind cardiovascular health for lifters, especially if you're focused on body recomp, strength training, weight loss, nutrition, and fitness. We cover the labs most people never get, how inflammation and metabolism shape heart health, and why tracking APOB, CRP, and oxidized LDL matters far more than total cholesterol. We also break down hormone health, HRT safety, muscle building over 40, and the peptides that actually support recovery and longevity.If you care about lifting weights, performance, and living longer with evidence-based fitness, this one gives you a clear roadmap. Tune in to learn more.Today, you'll learn all about:0:00 – Defining cardiovascular health3:40 – Mechanical vs biochemical heart health7:42 – Obesity, genetics, and heart disease12:10 – Key biomarkers to track18:55 – Inflammation patterns and risk23:20 – Cholesterol, genetics, and LDL nuance28:40 – Hormone health and HRT safety35:20 – Peptides for recovery and performance49:55 – Calcium scoring vs CCTA imaging*Episode resources:*Website: boulderlongevity.com Dr. Abid Husain's Instagram: @dr_abidhusain Boulder Longevity Institute's Instagram: @boulderlongevityinstitute LinkedIn: linkedin.com/in/abid-husain-md-facc-abaarm-00874419 YouTube: @boulderlongevityinstitute Facebook: @BoulderLongevityInstitute Support the show
Send us a textWhat if your body isn't underperforming… it's protecting you? We sit down with Renee McGregor, renowned sports and clinical dietitian, to unpack Relative Energy Deficiency in sport and why so many runners and active people feel flat, injured, or anxious despite training harder than ever. Renee explains how the body prioritizes movement when fuel is low and quietly turns down hormones, bone health, digestion, and immunity to keep you going—until it can't. We walk through real-world signs to watch for, why weight often doesn't change, and how stress from life and training compounds when recovery and nutrition timing fall short.Together we trace the messy intersection of REDs, overtraining, and personality traits like perfectionism and control. Renee shares how assessment actually works—history, labs, behaviors—and why recovery takes time: often 18 months for the body and longer for the brain to fully recalibrate. We also address a frequent blind spot for women in their 40s and beyond: perimenopause symptoms can mimic REDs. When to consider HRT, when fueling and rest are the missing pieces, and how both can coexist. The goal is clarity, not fear, and a practical path back to stable energy, resilient bones, and consistent performance.We challenge popular fasting trends with emerging research linking narrow eating windows to higher cardiovascular risk and explain how chronic cortisol undermines adaptation. You'll leave with simple, athlete-proven strategies: eat before and after hard work, fuel long sessions, protect sleep, and replace rigid control with flexible choices. Share this with a training partner who needs to hear it. If the conversation helped, subscribe, leave a review, and tell us: what's the first change you'll make this week?@r_mcgregor - Instagramreneemcrgregor.comBooks by Renee McGregor:Fuel for ThoughtMore Fuel YouTraining FoodOrthorexiaFast Fuel -Food for Triathlon Success coaching highlights You can reach out to us at:https://coffeycrewcoaching.comemail: Carla@coffeycrewcoaching.com FB @ Over the Next Hill Fitness GroupIG @coffeycrewcoaching.comand Buy Me a Coffeehttps://www.buymeacoffee.com/Carlauhttps://hydra-patch.com/discount/OTNH20 https://hydra-patch.com/discount/OTNHBOGO?redirect=%2Fproducts%2Fhydrapatch%C2%AE https://rnwy.life code: OTNH15 https://jambar.com code: CARLA20
In midlife, I see TONS of women who are “doing all the right things”—eating clean, exercising harder, even restricting more—yet still are seeing the scale creep up. That's why I've invited Sarah Kennedy on the podcast, who's the founder and CEO of Calocurb– a natural, non-prescription hunger control treatment option. We're unpacking why hunger can feel louder and more relentless than ever for women in midlife. Sarah breaks down how shifting hormones, chronic stress, poor sleep, and dwindling bandwidth all fuel food noise, cravings, and that constant tug-of-war with your appetite. You'll learn why willpower is not the problem—and why your biology deserves more compassion… not more restriction. Most importantly, Sarah shares practical, science-backed ways to calm midlife cravings and support your changing metabolism with more ease. Tune in here and finally make a change that shows you results! Sarah Kennedy Sarah Kennedy is the founder and CEO of Calocurb, a revolutionary weight-management product based in New Zealand. Calocurb now sells in five international markets and continues to grow rapidly. Sarah, formerly with Fonterra, held senior roles including Vice President International Farming in China and Managing Director of Dairy Nutrition and RD1 retail stores. Prior to joining Fonterra, she spent over 20 years in dietary and animal nutrition. A veterinarian by training, Sarah completed the Sloan Fellowship in Global Leadership and Innovation at MIT. IN THIS EPISODE How Calocurb can help curb your hunger, especially in midlife The physiology behind midlife hunger changes How Calocurb works and why it's different than synthetic GLP-1s The benefits of taking Calocurb in midlife Taking Calocurb safely alongside HRT and other supplements Dose timing and the best way to take Calocurb for results Fitting Calocurb into a broader wellness routine for women Get started with Calocurb with a 10% discount! QUOTES “When you reduce your calories by 25%, your hunger actually doubles over four months. So the brain is telling you to go out and look for food, and your body thinks you are going into a famine. So it's upping and upping and upping… this is why 99% of diets fail.” “I've been on it 6-7 years now. I don't take it twice a day, only take it once. But I can honestly say to you, I'm at peace with food… I think many, many people will find that.” “This has been revolutionary in the fact that we now understand what is happening in our body and what is driving this hunger and craving.” RESOURCES MENTIONED Calocurb: USE CODE DRMARIZA for 10% off your purchase! https://www.calocurb.com/drmarizasnyder Order my new book: The Perimenopause Revolution https://peri-revolution.com/ Use code ENERGIZED and get 10% off on your MitoQ order https://www.anrdoezrs.net/click-101585564-17091761 Calcurb on Facebook Calocurb on Instagram RELATED EPISODES #621: The Truth About Metabolic Health, Hormones and GLP-1s with Tyna Moore #558: The Science Behind Ozempic and Important Facts About GLP-1 Agonists + Hormone Replacement For Women 40+ with Dr. Tyna Moore #613: Effective Tools for Curbing Your Appetite in Midlife and Optimizing Your Blood Sugar with Nagina Sethi Abdullah #601: The Food You Eat Will Impact Your Menopause Journey + Foods to Ease Menopause and Promote Longevity with Dr. Federica Amati 696: Why Diets Stop Working in Midlife—and What Actually Helps Instead with Lara Frendjian
This episod is brought to you by Cured Nutrition, Caldera Lab and Joi & Blokes. Dr. Jessica Shepherd—OB/GYN, clinical advisor for P-Volv, and author of Generation M—breaks down everything women need to know about perimenopause, menopause, and longevity. She explains why mindset is the foundation of midlife health, how declining estrogen affects every organ system, why only 8% of symptomatic women ever receive a diagnosis, and how common comorbidities rise 45% or more between ages 40–59. Dr. Shepherd shares science-backed strategies for navigating symptoms, improving metabolic and mitochondrial health, understanding the truth about hormone therapy after the flawed WHI study (which led to an 82% decline in prescriptions), and using exercise, protein, and muscle-building to protect cognition, heart health, and overall vitality. Whether you're a woman entering midlife—or a partner wanting to better support her—this conversation is a masterclass in women's health, empowerment, and aging well. Follow Jessica @jessicashepherdmd Follow Chase @chase_chewning ----- 00:01 - Intro & shocking stats: women live longer but spend more years in poor health; HRT prescriptions dropped 82% after 2002 00:28 - Muscle as the organ of longevity; women lose 3–5% per decade, accelerated after menopause 01:18 - Why estrogen decline shifts the whole body; Dr. Shepherd introduces herself and her mission in women's health 02:15 - Redefining women's health & longevity; why women aren't thinking about longevity soon enough 04:23 – Mindset, habits, and community as the foundation of midlife health 07:13 - Barriers to staying well: socioeconomic factors, upbringing, access, and misconceptions about wellness 09:33 - Women's current wellness landscape; societal expectations, caregiving burden, and systemic gaps 12:46 – Major healthcare gaps: lack of research, exclusion of women from clinical studies until the '70s, and only 3% of VC health funding going to women 17:30 – Pharma eliminating women's health divisions; downstream effects on innovation and access 19:10 – Perimenopause 101: defining terms, symptoms vs. cycles, 34+ possible symptoms, and why diagnosis is trick 24:45 – The cardiovascular danger of estrogen decline; heart disease as the #1 killer of women 27:02 – Stress vs. perimenopause symptoms; mood disorders peak between 45–55 29:48 – How HRT has evolved in the last 10–20 years; symptom relief and longevity benefits 32:32 – Why only 5% of women are on hormone therapy today; misconceptions and new guidelines 34:20 – WHI study deep dive: media panic, misinterpretation, lack of statistical significance, and lasting fear 39:06 – Risk vs. benefit: how to think about HRT decisions with your provider 41:51 – Chase shares his TRT story; quality of life, fertility considerations, and hormone literacy 45:16 – Dr. Shepherd's personal hormone story: cognition issues, testosterone, and starting estrogen at 46 48:12 – Supplements Dr. Shepherd uses: Vitamin D, creatine, CoQ10, Urolithin A 50:10 – Muscle, mitochondrial health, sarcopenia & glucose control: why resistance training is non-negotiable 52:25 – Movement, neuroplasticity, balance & cognition: why staying active protects the aging brain 55:12 – How partners can best support women in perimenopause: emotional support & shared routines 57:52 – The science of emotional support: social connection decreases pain, inflammation, and improves outcomes 59:22 – Menopause explained: average age, symptom timeline, and the hidden cellular changes 01:02:39 – Nutrition, glucose control, protein needs, alcohol & sugar intake, and metabolic health 01:07:07 – Protein requirements (1.0–1.2g/kg), resistance training, and why women must build muscle 01:09:37 – U.S. data: 55%+ of women report symptoms; only 8% diagnosed; why doctors miss it 01:12:34 – Which providers are best for menopause care & what certifications to look for 01:15:31 – Comorbidities rise 45% between 40–59: hypertension, thyroid, arthritis, sleep disorders & estrogen's role 01:18:25 – Is biohacking menopause possible? Current limits + ovarian longevity research 01:22:24 – Exercise as the ultimate biohack; sustainable movement for aging wel 01:23:19 – Final Q: How Dr. Shepherd lives Ever Forward — flexibility, pause, and growth ----- Episode resources: 20% off DREAM gummies with code EVERFORWARD at CuredNutrition.com/everforward 50% off any product or diagnostic labs with code CHASE at JoiAndBlokes.com/chase 20% off any men's skincare product with code EVERFORWARD at CalderaLab.com Watch and subscribe on YouTube
Dr. Laura Buchanan joins Dr. Tro to discuss health strategies and lifestyle optimization to help women understand their hormonal journey through perimenopause, menopause, and postmenopause. In this episode, Drs. Tro and Laura talk about… (00:00) Intro (04:22) How Dr. Laura helps her female patients address their hormonal issues (09:52) Systemic medical gaslighting (13:05) Symptoms of menopausal transition (18:08) The history of hormone treatment and how Dr. Laura treats women struggling with hormonal issues (28:38) Hormone replacement therapy (31:58) Testosterone replacement (37:20) How Toward Health helps their patients achieve hormonal health (44:05) HRT success stories (46:56) Using hormone replacement therapy responsibly (53:35) Breast cancer risk from HRT (56:17) HHS admitting being wrong HRT (01:01:31) Outro For more information, please see the links below. Thank you for listening! Links: Please consider supporting us on Patreon: https://www.lowcarbmd.com/ Resources Mentioned in this Episode: Women's Health and Hormones Course: https://toward.health/womens-health-and-hormones/ Dr. Laura Buchanan: Twitter: https://twitter.com/LauraBuchananMD The Society of Metabolic Health Practitioners: https://thesmhp.org/ Website: https://www.iheartvitae.com/ Instagram: https://www.instagram.com/iheartvitae/?hl=en Dr. Brian Lenzkes: Website: https://arizonametabolichealth.com/ Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author Dr. Tro Kalayjian: Website: https://www.doctortro.com/ Twitter: https://twitter.com/DoctorTro IG: https://www.instagram.com/doctortro/ Toward Health App Join a growing community of individuals who are improving their metabolic health; together. Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more. Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888 Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US Learn more: https://doctortro.com/community/
For more info on how I can help you, visit my site BetterByDrBrooke. The holidays are here, and it's time for the 10th annual Thanksgiving episode! Can you believe it? Gratitude is a powerful and it is tricky. I'll share some new research on the science of gratitude and how it can be an important tool for resilience due to how it triggers a potent feel-good hormone cocktail in our nervous system. I'll also cover a few places where it's easy to get gratitude quite wrong. AND the annual 15% off sale is on at BetterByDrBrooke.com! Use code GRATITUDE15 to save on all of the Better By Dr Brooke supplements. If you have any other product you don't see online but need, email Jess at admin@betterbydrbrooke.com. Resources mentioned in this episode: Finding Your Inner Compass FREE download. This is my core value exercise and it's one of my fav tools for actually shifting your experience of stress. Dr Brooke's Happy Holidays Gluten/Dairy Free Menu Grab the Midlife Is More Than HRT guide free right here if, like me, midlife didn't feel quite like you expected. And be sure to listen to episodes #438 and #439, which were all about the mess that midlife can be, and my 3G+4R process to tackle it! Stuff I Know You Will Love If you are looking for an expert prescriber for HRT during your perimenopause or menopause journey but are at odds with your local provider being a bit behind current best practices or you simply can't find anyone near you to help, it is MIDI to the rescue! I've worked with a number of telehealth services in my search for providers that are up to date on modern menopause medicine, have great customer service, and are licensed in all 50 states and I'm so thrilled to have found my provider with MIDI. If you too need help with getting HRT please use this link bit.ly/drbrookemidi to try MIDI with no membership fees and insurance billing available. Be sure you connect with me in my FREE PRIVATE Facebook group: Hormones & Happiness with Dr. Brooke where other amazing, like-minded women like YOU are already hanging out! Join us! Follow Dr. Brooke on Instagram and get signed up for my awesome emails here. Seriously, I write really great emails, or so 1000s of women tell me and I'd like to send you one too. To work with Dr. Brooke click here and if you loved this episode please leave a review!