The Pulse

If you go by pop culture depictions, menopause seems like no big deal — a few hot flashes, some comical bouts of hormone-fueled rage, and the “big change,” as it was once called, is over. But for many of the 2 million American women who enter menopause each year, the symptoms can be a lot more serious and long-lasting, ranging from vertigo and joint pain to brain fog and heart problems.On this episode, we take a deep dive into perimenopause and menopause – what's going on biologically? What can be done to ease symptoms? And why do so many women struggle to receive help from their doctors?We talk with menopause experts about hormone replacement therapy, and why it was demonized for many years; find out what researchers have discovered about the causes of brain fog; and hear about new efforts to deal with medically induced menopause. In this excerpt from our live event, Reimagining Menopause, host Maiken Scott talks with two certified menopause providers — Robyn Faye, an OB-GYN at Jefferson Health in Philadelphia, and Arina Chesnokova, assistant professor in of Obstetrics and Gynecology at the University of Pennsylvania's Perelman School of Medicine — about the ins and outs of hormone therapy, which symptoms it alleviates, when it's safe and when it's not. Watch the full discussion here. Reporter Alan Yu talks with researchers about what's behind one of the most vexing symptoms of menopause for many women — brain fog. For women who have cancer when they're younger, especially breast or ovarian cancer, chemotherapy and other medications needed to treat the disease can affect hormones - and suddenly plunge them into menopause, years before they might naturally experience it. We explore what their options are, and why so many say they were not prepared for this change.

Capsule wardrobes have become a popular way to streamline and organize your closet — basically, paring it down to a few staple pieces that you can combine in multiple ways, and freshen up with seasonal accessories. Registered Dietitian Jenn Salib Huber says this is how women should think about nutrition during perimenopause and menopause. Rather than obsessing over calorie counts and macronutrients, they should focus on staples like soy and fish that are not only delicious but can also alleviate symptoms like hot flashes or brain fog. Huber joins us to discuss her new cookbook, “Eat to Thrive During Menopause.” She offers advice for getting the most out of your meals, tells us which ingredients are “must-haves” during menopause, and shares some of her favorite recipes.

Think about the last time you were really happy — where were you? What were you doing? Who were you with? And, most importantly, how can you recreate that feeling?Happiness can feel like lightning in a bottle — beautiful in the moment, but hard to find and harder yet to sustain. So what is it that makes for a happy life? And how do we engineer our lives for greater contentment, fulfillment, and joy?On this episode: the science of happiness and how we can experience more of it every day. We talk with psychologist Eric Zillmer about why certain places bring us joy, and how to engineer happiness in our lives. We hear about one reporter's experiment to bring more moments of serendipity in her life. And, writer Daniel Coyle explains why community is at the heart of what it means to flourish.Drexel University psychologist Eric Zillmer created a “happiness map” of Philadelphia with the help of his students. He says it holds greater lessons on why certain places bring us joy, and how we can reverse-engineer happiness into our days. Zillmer directs the happiness lab at Drexel University.Writer Daniel Coyle built his career on exploring what it is that makes people successful — but when both of his parents died a few years ago, Coyle found himself unmoored, questioning what makes for a happy and meaningful life. The resulting journey led to his newest book, “Flourish: The Art of Building Meaning, Joy, and Fulfillment.” We talk with Coyle why he says community is at the heart of flourishing, how to create the right conditions for happiness, and why he says life isn't a treasure hunt — it's the process of treasure creation.

For a lot of us, noise is a constant factor — an inescapable soundtrack playing on loop in the background. Kids screaming, sirens blaring, the roar of traffic, the sounds of music, lawn mowers, construction, and so much more.We ignore it when we can, or wear headphones to block out the racket. But all that noise can actually damage our hearing and, subsequently, our overall health. On this encore episode, we explore what researchers are learning about the connections between noise, hearing loss, and our well-being. We find out whether constant headphone listening could put our hearing at risk, and why live concerts are so loud, along with how to protect your ears. Also, why stigma remains around hearing aids, even though so many people need them.SHOW NOTES:We talk with exposure scientist Rick Neitzel about the long-neglected topic of noise pollution and its effects on our health. He explains the physiological effects of noise, theories on how it causes harm, and some of the most common sources of damaging sound exposure.Meg Wallhagen — a geriatric nurse practitioner and hearing loss researcher — explains age-related hearing loss, and why there still remains a stigma against hearing aids.

Twenty-five years ago, President Bill Clinton stood before a podium in the East Room of the White House, and, in front of an all-star lineup of researchers and dignitaries, made a historic announcement: After years of painstaking work, scientists had created “the most important, most wondrous map ever produced by humankind” — the first-ever survey of the human genome.In his remarks, Clinton compared the achievement to the maps created by Lewis and Clark's expedition into the American West — but maybe a comparison to the space race would have been more accurate. Because, behind the scenes, the journey leading up to that day's announcement had been defined by nerve-wracking, cut-throat competition — a competition where every minute counted, and the future of scientific inquiry was at stake.On this encore episode, we look back at how what started as a scientific collaboration fractured into a bitter race to finish decoding the human genome. On one side was the federally funded Human Genome Project; on the other, a private start-up called Celera; and, in between, a raucous mashup of conflicting personalities, values, and ideas that would eventually help to transform science and medicine.

As patients, we often wonder what our role should be when it comes to getting better. Should we research options, get second opinions, and ask lots of questions? Or should we sit back, and let the health care professionals take charge? When does it make sense to push, and when is it best to do less?On this episode, we examine our role as patients, the choices we make, and charting our path toward better health. A reporter gets a wake-up call while looking into diabetes rates among Latinos in Oklahoma, we hear about one woman's choice to forgo cancer treatment — and how her family and doctors responded, and we explore a controversial proposed diagnosis for severe, long-term anorexia. SHOW NOTES: First Juliet Wayne's brother died from cancer — then her long-term partner broke up with her. That was followed by a deep depression; and then, the nightmares started. We talk with Wayne about how these nightmares affected her life, why doctors said she couldn't take a drug designed to stop them, and how a chance encounter finally led her to relief. Historian Joy Lisi Rankin talks about her mother's choice not to pursue treatment for breast cancer — and how Rankin's own experience years later with breast cancer treatment changed how she felt about her mother's choices. You can read Rankin's essay about her mother at Stat News. Anorexia has one of, if not the, highest mortality rates of any mental illness, with a relatively low recovery rate. Patients and their families suffer deeply from this illness, which can last for decades. In 2022, a paper proposed a new and controversial diagnosis: terminal anorexia. Reporter Elizabeth Zwerling tells the story of how this diagnosis came to be proposed, and the difficult conversations it kicked off in the world of eating disorder treatment.

In 1973, Stanford psychologist David Rosenhan published a bombshell paper called “On Being Sane in Insane Places.” In the paper, Rosenhan described faking symptoms to be admitted to a psychiatric hospital, and recruiting several other pseudo patients to do the same. Could staff tell they were faking? What was it like to be a patient in an institution? The “Rosenhan experiment,” as it came to be known, created a major stir, sparking public debates over the validity of psychiatric diagnoses and contributing to a shift away from institutionalization. Decades later, when journalist Susannah Cahalan began looking into the experiment, she made a startling discovery about Rosenhan's famous research; he had made up most of it.On this episode, we explore what happens when long-held narratives are upended. For the first time, we hear the voices of the pseudo patients who participated in the famous study, and find out why Cahalan was so passionate about finding them. We'll also hear a story about one woman's decades-long search to investigate the Oklahoma City bombing that killed her two grandsons.SHOW NOTES: The reason Susannah Cahalan was so interested in the Rosenhan experiment was personal — she had her own brush with the mental health system. Check out this week's edition of KQED's Snap Judgment, where she tells that story. It starts with Cahalan waking up in a hospital room, and having no idea why she's there.  Kathy Sanders' grandsons, Chase, 3, and Colton, 2, were killed in the Oklahoma City bombing on April 19, 1995. Sanders felt numb with grief and sadness — but soon, another emotion crept in: doubt. She felt that the federal investigation was dropping leads, and not pursuing important clues. Reporter Grant Hill talks with Sanders about what she found in her own investigation, and why, 30 years later, she's still looking for the truth. 

Over the course of 20 years, writer Neil Shea explored the awe-inspiring landscape of the Arctic. He saw narwhals poking their tusks above the water, herds of caribou moving across the tundra, and majestic white wolves raising their young. He documents this fragile beauty in his new book, “Frostlines.” We talk to Shea about his adventures, and how climate change is transforming the region.

So often, our relationships take a backseat to everything else on our to-do lists — but new research shows that nurturing personal connections plays a central role in our health and well-being. On this episode, we explore the science of connection, from why it's important, to how we can make it a priority in our lives.

Ahead of Thanksgiving, we do a deep dive into what we actually know about diet, and what we should and shouldn't be eating. We talk with a nutrition and metabolism scientist about recent diet trends and how they affect our health, hear from several chefs about how they balance nutrition and taste, and find out how the avian flu outbreak could be affecting this year's turkeys.

How do our dreams connect to health, and how could “dream engineering” help people get over nightmares? Researcher Michelle Carr writes about that in her new book “Nightmare Obscura: A Dream Engineer's Guide Through the Sleeping Mind.” We talk with Carr about why we dream, the benefits of lucid dreaming, and what she's learning about our ability to “engineer” our dreams.

Chatbots don't have feelings of their own, but they've been stirring plenty of emotions in us humans. On this episode, we explore how AI is making us feel, and what those feelings say about us. We hear about using ChatGPT for DIY therapy, what kinds of personalities we prefer in our chatbots, and how both the market and online culture is responding to the spike in AI-generated content.

On this Veterans Day episode, we explore the invisible wounds of war — and the different paths veterans take to heal them. We talk with a Marine Corps vet about how ceramics helped him reconnect with civilian life, a retired Navy SEAL about his experience with psychedelic-assisted therapy, and a Vietnam vet who, decades after the war, found peace in an unexpected place.

Cybercrime has been around for as long as computers have — but over the past 20 years, it's exploded into a global threat, with staggering financial, political, and even personal consequences. On this encore episode, we hear about the virus that ushered in the age of social engineering attacks, the history of cybercrime, and what led one man to become a hacker.

Coca-Cola is launching a cane sugar version of its classic soda in the U.S. after President Donald Trump urged a switch from high fructose corn syrup. The effort supports the administration's “Make America Healthy Again” initiative — but many experts argue that it won't make a difference.  On this episode, journalist Murray Carpenter discusses his new book, Sweet and Deadly: How Coca-Cola Spreads Disinformation and Makes Us Sick.

Ghosts seem far out of the realm of science. But small groups of investigators remain committed to proving — or disproving — the existence of paranormal phenomena. On this episode, we find out what motivates these investigators, and we'll hear about a lab on the UCLA campus that studied paranormal activities.

If it feels like urgent care centers are everywhere these days — that's because they are. Over the past decade, they've exploded in popularity, offering a quick and convenient alternative to long waits at the ER, and even longer waits to see your primary care provider. On this episode, we explore the rise of urgent care, from the role of private equity to its impact on patient care.

What if treatments or even cures for devastating rare diseases already existed — and were just waiting to be discovered? On this podcast extra, we dive into the extraordinary journey of physician and researcher David Fajgenbaum, cofounder of Every Cure. After facing death five times due to a rare illness called Castleman Disease, Fajgenbaum not only discovered his own treatment, but also launched an ambitious project using AI to unlock existing drugs for countless other conditions. He has a new TED Talk and was recently featured in Time Magazine's list of “The World's Most Influential Rising Stars.” Fajgenbaum's life is also the subject of an upcoming movie based on his memoir “Chasing My Cure.” Listen to his incredible story of resilience, the profound lessons he's learned from living in "overtime," and how his work is already saving lives by repurposing treatments hiding in plain sight.

We often think of digital distractions, from TikTok to newsfeeds, as a way of giving our brains a break. But in reality, they could be doing the opposite. We talk with psychologist Marc Berman about a better way of restoring our focus — spending time in nature. We also try a dopamine fast, to see if it can really improve our attention spans.

Many adventurers and researchers feel the call of the wild — a force tugging them to explore, climb distant mountains, venture into faraway forests, and discover or rediscover something: a creature, a place, some new clue. On this episode: Adventures in the Wild, featuring the mythical golden toad, raging elephants, and poisonous snakes.

In its heyday, “The Biggest Loser” was one of the biggest shows on TV. But now, nine years after it went off the air, a  Netflix docuseries and new book by leading obesity researcher Kevin Hall, are prompting a re-examination of the show's tactics, and some of the surprising discoveries it led to surrounding metabolism and weight loss.

Different Patients, Different Outcomes

Most of us take our muscles for granted, but they play a bigger role in our physical and mental health than most people realize. On this encore episode, we explore their cultural and scientific significance. We hear about the history of weight-lifting, along with how it went from niche hobby to medical treatment, and learn about the intricate biology and beauty of our muscles.

When we see surprising couples, like Liam Neeson and Pamela Anderson, we can't help but wonder what brought them together. In this podcast extra, we explore the mysteries of attraction and love. We talk with researcher Paul Eastwick about the idiosyncratic factors that go into attraction, and behavioral scientist Logan Ury coaches us on the science of optimizing online dating.

We think of Martians as belonging to the realm of sci-fi — but in the early 1900s, a radical idea swept the nation, scientists included: that Martians weren't only real, they were intelligent beings with their own sophisticated civilization. On this episode, we hear about the astronomer who pushed “Mars Mania,” and a cautionary tale of what happens when belief trumps science.

It seems like we're all constantly striving to be more productive — to find the right hacks or systems or habits that will allow us to squeeze more from our days. But is maximum  productivity really desirable, or are we missing the bigger picture while running on that treadmill? On this episode, we look at productivity — what works, what doesn't, and how we can redefine it in a changing world.

It's back-to-school time, which, for millions of families across the country, means a return to bedtimes, shopping for school supplies, and frantic efforts by kids to finish their summer reading. On this episode, we explore how our fast-changing world is transforming learning and life inside the classroom, from the lingering effects of the pandemic, to the impact of generative AI tools, to the pressures of “Ivy League fever.”Interviews with host Maiken Scott:When COVID-19 hit the U.S. in March 2020, schools across the country closed down — and stayed closed — as part of an effort to stem the pandemic's spread. At the time, it seemed like the right move for public health — but according to investigative reporter David Zweig, the basis for those closures was a lot shakier than the public knew, the benefits less clear, and the impact on kids more profound than we imagined. He joins us to discuss his new book, “An Abundance of Caution: American Schools, the Virus and a Story of Bad Decisions.”We talk with education reporter Holly Korbey about how the adoption of new technologies — from Smartboards, to laptops, to ChatGPT — are transforming the classroom, and what science has to say about whether those changes are good or bad for learning. Korbey writes The Bell Ringer, a newsletter on the science of learning.

In the summer of 1976, when 2,000 people came to Philadelphia for a national convention of the American Legion, a strange illness gripped hundreds of attendees, and more than 30 people died. Symptoms included cough, shortness of breath, and fever. Was it a virus, bacteria, some sort of toxin? A major investigation was launched by the CDC — and the gathering in Philadelphia became forever tied to one of the greatest medical mysteries of our time.   Almost 50 years later, reports of Legionnaires' Disease are in the news again. Reporter Elana Gordon tells the story of how scientists — with some serious shoe-leather detective work and a scientific breakthrough — tracked down the origin of this mysterious airborne illness. On this episode, we listen back to her reporting from 2016: Audio Time Capsule: The discovery of Legionnaires' disease.

Farming is a tough gig — physically, and mentally.  And it's only gotten harder in recent years, with the impact of climate change and a shifting political and economic landscape. On this episode, we explore the connection between farming and health, and how these new challenges are affecting the well-being of the people who produce our food.

We live in a noisy world — from the din of busy restaurants, to the roar of traffic, to the clamor of partying neighbors. We'll explore what researchers are learning about the connections between noise, hearing loss and our well-being.

On this episode, we explore the stories of people who survived extraordinary trials, from life-threatening illnesses to assault, and ask what came after survival. We'll hear what it's like to survive — and come back from — locked-in syndrome, explore the emotional roller coaster of being a young cancer survivor, and find out how one writer created guide to intimacy after sexual assault.

More than a hundred thousand people in the U.S. are on the national transplant list waiting for a life-saving organ. Hospitals across the country transplant more than 45,000 organs each year and there are rules and protocols about how it is supposed to go. But what happens when the process fails?The New York Times investigative reporter Brian Rosenthal joins us to discuss some recent cases where doctors discovered that patients were still alive and conscious when the donation process was underway. He talks with host Maiken Scott about a relatively new method of procuring organs, called circulatory death donation, and new pressures on procurement organizations that could be jeopardizing safety.Rosenthal and his colleague Julie Tate recently published an investigation in The New York Times called, “A Push for More Organ Transplants Is Putting Donors at Risk.”

Shame has a way of making us feel alone — like we're the only ones in the world struggling with something. It can make us withdraw or feel depressed, out of control, and helpless. In the worst cases, it can destroy our self-esteem and even lead to self harm. But shame can also be a force for positive change, from enforcing social norms, to pushing us to improve our behaviors and circumstances. On this episode, we untangle why we feel it, where shame comes from, and how it affects our behavior and health. Lots of us have hangups about what we look like in swimsuits — but wait until you hear about what “kind of attire” used to be acceptable at pools. We'll explore the evolutionary roots of shame, how one woman discovered what was behind her monthly meltdowns, and how shame figures into treatment approaches in the opioid epidemic.

What comes to mind when you think of the ocean? Maybe a day at the beach — swimming in the waves, snorkeling through coral reefs, fishing, surfing, and sunsets that kiss the blue horizon. But Earth's oceans are more than that; they're our planet's defining feature, its largest ecosystem, and the original source of all life. On this encore episode, we explore the engine that powers our planet.

We often think of sleep as the gas that keeps us running. We refuel at night — or whenever we can — run around all day until our tanks are empty, and then do it all over again the next day. But some sleep scientists would like us to think about sleep less as fuel, and more as a biological rhythm — one that's as essential to our overall health as our heartbeat. On this episode, we'll explore how finding your body's unique sleep rhythm can help you get better rest.

We've only been able to harness the cold for our benefit for a little over 100 years, but innovations like refrigeration and air conditioning have completely transformed the way we live and eat. But it all comes at a cost — and not just financially. On this encore episode, how advances in cold technology have shaped our lives and changed the world. 

Twenty-five years ago, President Bill Clinton announced a historic achievement: The completion of the first-ever survey of the human genome. The ceremony focused on the power of unity and collaboration — but, behind the scenes, the journey to this generational discovery had been marked by a bitter, cut-throat competition. We  look back at the race to decode the human genome — and who really won.

Friends make us laugh, they have our back, we share memories and stories. Beyond that, scientists are learning that friendships are key in keeping us healthy and thriving. On this episode, we explore why researchers say our brains are wired for connection, and why making our friendships a priority is one of the key pillars of longevity. We'll get some research-backed advice on making new friends as adults and hear from two friends who love spending time with each other, though they usually can't remember their adventures.

When someone wrongs us, getting revenge can feel like the only right move — the only way for us to balance the scales, to set the world right again. But the consequences can be disastrous, especially when payback becomes an all-consuming obsession. On this episode, we talk with lawyer-turned-researcher James Kimmel about his new book, "The Science of Revenge: Understanding the World's Deadliest Addiction — and How to Overcome It." We discuss the evolutionary roots of revenge, the neuroscience behind why it feels so good, and how Kimmel eventually traded vengeance for forgiveness. We also find out what caused a murder of crows to target an unsuspecting woman, and what was behind their years-long grudge.

Creativity plays a role in every facet of our lives, from childhood education, to everyday problem-solving, to the artistic works we enjoy and the innovations shaping our future. We explore what human creativity is, how it works, and some of the unexpected ways it's remaking our world.

Before dinosaurs, before trees — even before Saturn had its rings – there were sharks. The fierce predators have been swimming in our oceans for hundreds of millions of years, standing the test of time as they survived all five of Earth's mass extinction events.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

We all want the truth — but how exactly do we know when something's true? Often, the answer relates to evidence or proof, something capable of convincing us and easing our doubts. But whether or not different kinds of proof are accepted can vary widely by person and situation. On this episode, we explore proof and evidence, and how it affects our perception of what is true.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy