The Weekly Bioanalysis - The Official Podcast of KCAS

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"The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 200 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA and Milan, Italy, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

KCAS


    • May 28, 2025 LATEST EPISODE
    • monthly NEW EPISODES
    • 1h 11m AVG DURATION
    • 89 EPISODES


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    Latest episodes from The Weekly Bioanalysis - The Official Podcast of KCAS

    Balancing Growth with Employee Experience, Part 1 - Special Guest, Jeff Goddard

    Play Episode Listen Later May 28, 2025 96:52


    In Episode 89 of The Weekly Bioanalysis, hosts Dominic Warrino and John Perkins engage in a compelling conversation with special guest, Jeff Goddard, Senior Vice President of Corporate Development at KCAS Bio. The three delve into KCAS Bio's strategic growth, including the acquisition of France-based Active Biomarkers, which expanded the company's transatlantic presence. Jeff shares insights into the evolving landscape of bioanalytical services and how KCAS Bio is positioning itself to meet the challenges of modern drug development. The discussion also touches on the importance of collaboration and innovation in accelerating therapeutic discoveries.“The Weekly Bioanalysis” is a podcast dedicated to discussing bioanalytical news, tools and services related to the pharmaceutical, biopharmaceutical and biomarker industries. Every month, KCAS Bio will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the bioanalytical world the past couple of weeks. “The Weekly Bioanalysis” is brought to you by KCAS Bio.KCAS Bio is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the pharmaceutical, biopharmaceutical, animal health and medical device industries.

    Reflections on WRIB 2025 in New Orleans - With ALL the Guests!!

    Play Episode Listen Later Apr 28, 2025 73:07


    In Episode 88 of The Weekly Bioanalysis, hosts Dominic Warrino and John Perkins present a special WRIB 2025 recap featuring several KCAS Bio scientists who share firsthand insights from their presentations at the major bioanalytical conference. Dave Ambrose highlights KCAS Bio's global harmonization of spectral flow cytometry instruments across sites in the U.S., France, and Australia, showcasing the industry's first off-the-shelf spectral flow panel with impressively tight inter-site CVs. Jessica Pham discusses her work on a VAMS-based PK assay for an anti-malarial monoclonal antibody, designed to enable microsampling in remote regions with high temperature stability. Bryan Parmentier presents a novel method for overcoming matrix effects in cisplatin assays by adding exogenous hemoglobin, a breakthrough inspired by clinical anemia observations. The episode concludes with a group discussion about the implications of new biomarker guidance from the FDA and ICH M10, sparking debate on validation standards, regulatory interpretations, and industry alignment.“The Weekly Bioanalysis” is a podcast dedicated to discussing bioanalytical news, tools and services related to the pharmaceutical, biopharmaceutical and biomarker industries. Every month, KCAS Bio will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the bioanalytical world the past couple of weeks. “The Weekly Bioanalysis” is brought to you by KCAS Bio.KCAS Bio is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the pharmaceutical, biopharmaceutical, animal health and medical device industries.

    Evolution of SCIEX's Partnership with Pharma in Drug Discovery & Development

    Play Episode Listen Later Mar 28, 2025 50:26


    In episode 87 of The Weekly Bioanalysis podcast, John Perkins and Dawn Dufield preview the upcoming WRIB conference, where KCAS Bio and Sciex will both have strong representation through scientific presentations, panels, and business development efforts. Special guest, Rahul Baghla of Sciex, discusses the company's collaboration with KCAS Bio and introduces their high-throughput Echo technology, which uses acoustic ejection to improve speed and reduce carryover in early discovery assays. The conversation explores the evolution of mass spectrometry platforms, highlighting the robustness and sensitivity of Sciex's 7500+ system and the increasing role of AI in streamlining data analysis. Dawn and John reflect on the challenges of adopting new technologies in regulated environments, emphasizing the balance between innovation and practical application.“The Weekly Bioanalysis” is a podcast dedicated to discussing bioanalytical news, tools and services related to the pharmaceutical, biopharmaceutical and biomarker industries. Every month, KCAS Bio will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the bioanalytical world the past couple of weeks. “The Weekly Bioanalysis” is brought to you by KCAS Bio.KCAS Bio is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the pharmaceutical, biopharmaceutical, animal health and medical device industries.

    Immunogenicity Discussion w/ Special Guest Cheikh Kane – What is a Lean ADA?

    Play Episode Listen Later Feb 28, 2025 77:16


    During episode 86 of KCAS Bio's "The Weekly Bioanalysis" podcast, our hosts Dom and John are joined by Dr Cheikh Kane, the Vice President of Biopharma Services at KCAS Bio, to discuss immunogenicity. They first define Immunogenicity; what it is and why it is tested, as well as the standard approach for ADA testing before answering the question of "What is a 'Lean' anti-drug antibody (ADA) approach, and when should it be employed?". Dr Kane brings his decades of experience and biopharmaceutical expertise to a very impressive conversation that showcases the many options involved in ADA testing. This is one you won't want to miss!“The Weekly Bioanalysis” is a podcast dedicated to discussing bioanalytical news, tools and services related to the pharmaceutical, biopharmaceutical and biomarker industries. Every month, KCAS Bio will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the bioanalytical world the past couple of weeks. “The Weekly Bioanalysis” is brought to you by KCAS Bio.KCAS Bio is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the pharmaceutical, biopharmaceutical, animal health and medical device industries.

    Patient-Centric Sampling: Beyond the Clinic and What it Means for Bioanalysis

    Play Episode Listen Later Jan 28, 2025 95:35


    Dom and John, the hosts of “The Weekly Bioanalysis”, recently returned from EBF in Barcelona where there was a session on Patient-centric Microsampling, which both of them founnd fascinating. This inspired both of them to decide it was high time to revisit this part of our industry. In spite of a few infamous setbacks caused by the dishonesty of a few bad actors within the industry a years ago, there has been a renewed interest in patient-centric sampling, and our hosts have invited one of the pioneers in this field, Dr Neil Spooner, to join them on episode #85 to discuss the recent advances in the reemerging science around microsampling. They discuss Dried Blood Spot Analysis, device-based sampling vs conventional assays, the devices currently available, and what all of this might mean for the future of bioanalysis.“The Weekly Bioanalysis” is a podcast dedicated to discussing bioanalytical news, tools and services related to the pharmaceutical, biopharmaceutical and biomarker industries. Every month, KCAS Bio will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the bioanalytical world the past couple of weeks. “The Weekly Bioanalysis” is brought to you by KCAS Bio.KCAS Bio is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the pharmaceutical, biopharmaceutical, animal health and medical device industries.

    Small Molecule LC-MS Development and Evolving Approach to ADC Payloads

    Play Episode Listen Later Dec 28, 2024 92:24


    In episode 84 of “The Weekly Bioanalysis”, our special guest, Bryan Parmentier, joins Dom and John to discuss his background and current role at KCAS Bio, offering insights into the field of small molecule method development. He delves into the typical challenges encountered when working with LC-MS analytes, and how the evolving role of LC-MS continues to shape the industry. Parmentier emphasizes the value of pre-validation in ensuring method robustness and shares lessons learned from developing methods for antibody-drug conjugate (ADC) payloads. He also details the revised KCAS Bio approach for method development of ADC payloads and the associated downstream validation experiments. This episode provides valuable insights for professionals involved in bioanalysis, particularly in the context of complex analytes and cutting-edge therapeutics.“The Weekly Bioanalysis” is a podcast dedicated to discussing bioanalytical news, tools and services related to the pharmaceutical, biopharmaceutical and biomarker industries. Every month, KCAS Bio will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the bioanalytical world the past couple of weeks. “The Weekly Bioanalysis” is brought to you by KCAS Bio.KCAS Bio is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the pharmaceutical, biopharmaceutical, animal health and medical device industries.

    Recap of the European Bioanalysis Forum Open Symposium

    Play Episode Listen Later Nov 27, 2024 77:51


    The 2024 tradeshow and conference season is finally coming to a close for the pharmaceutical and biotech industry, and our road-weary traveling hosts, Dom and John have returned from their final event, the 2024 European Bioanalysis Forum (EBF) Open Symposium in Barcelona, Spain. EBF was founded in 2006 at the initiative of 12 pharmaceutical companies. The goal was to create a platform for discussions around science, day-to-day procedures, business tools, technologies and - last but not least - regulatory issues. The theme of the conference this year was “Taking the temperature of bioanalysis”, which is exactly what the guys have come back to discuss here for the 83rd episode of “The Weekly Bioanalysis” podcast!“The Weekly Bioanalysis” is a podcast dedicated to discussing bioanalytical news, tools and services related to the pharmaceutical, biopharmaceutical and biomarker industries. Every month, KCAS Bio will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the bioanalytical world the past couple of weeks. “The Weekly Bioanalysis” is brought to you by KCAS Bio.KCAS Bio is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the pharmaceutical, biopharmaceutical, animal health and medical device industries.

    Conference Season 2024: KCAS Bio's Upcoming Exhibitions & Presentations

    Play Episode Listen Later Oct 28, 2024 92:03


    It's conference season! This is a busy, busy time of the year for the entire industry, when everyone comes together from around the world to share, listen and discuss the changes and advancements taking place in the business and science of the pharma and biotech space. During this episode of “The Weekly Bioanalysis”, our hosts, Dom and John, go over all the places – around the world – where the KCAS Bio team will be taking part in exhibitions, panels and presentations. From Europe to Australia and all over the U.S., KCAS Bio will be attending a number of events, conferences and trade shows, featuring all the great things our organization has been up to over the last year or so. There is so much to go over, and we hope to see you at many of these industry events!“The Weekly Bioanalysis” is a podcast dedicated to discussing bioanalytical news, tools and services related to the pharmaceutical, biopharmaceutical and biomarker industries. Every month, KCAS Bio will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the bioanalytical world the past couple of weeks. “The Weekly Bioanalysis” is brought to you by KCAS Bio.KCAS Bio is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the pharmaceutical, biopharmaceutical, animal health and medical device industries.

    GLP-1 Analogue Bioanalysis: The Value of Complimentary Technologies

    Play Episode Listen Later Sep 28, 2024 69:35


    After such a great response to our recent episode on the topic, our hosts, Dom and John, revisit the topic of GLP-1 Analogue development and the role bioanalysis plays in this relatively new and popular topic. In the words of John, “Everyone else is talking about this; why shouldn't we?” And wow, do they have a lot to say about it on this second pass at the advances being made in this ever-growing and ever-changing field. The guys talk about the latest developments in the GLP-1 Analogue space, KCAS Bio's experience with GLP-1 Analogs, options when choosing the right technology for these studies, some of the challenges associated with the LC-MS Approach, the options available around Ligand Binding Assays for GLP-1 Analogues in tissues, and whether there may even be value in conversation about a Hybrid LC-MS approach!“The Weekly Bioanalysis” is a podcast dedicated to discussing bioanalytical news, tools and services related to the pharmaceutical, biopharmaceutical and biomarker industries. Every month, KCAS Bio will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the bioanalytical world the past couple of weeks. “The Weekly Bioanalysis” is brought to you by KCAS Bio.KCAS Bio is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the pharmaceutical, biopharmaceutical, animal health and medical device industries.

    The Rapid Evolution of PCR Assays with Special Guest, Carrie Vyhlidal

    Play Episode Listen Later Aug 28, 2024 82:46


    Our hosts, Dom and John, are excited to welcome special guest, Carrie Vyhlidal, to discuss the topic of the 80th episode of “The Weekly Bioanalysis” podcast – The Rapid Evolution of PCR Assays. PCR (or Polymerase Chain Reaction) is like a copying machine for DNA. Scientists have found ways to measure the copies being made throughout the reactions, which is where they get their real-time, quantitative PCR (or qPCR). Carrie does a wonderful job of explaining not only why these advancements in the study of PCRs are so amazing – but also why they play (and will continue to play) such an important part in bioanalysis.“The Weekly Bioanalysis” is a podcast dedicated to discussing bioanalytical news, tools and services related to the pharmaceutical, biopharmaceutical and biomarker industries. Every month, KCAS Bio will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the bioanalytical world the past couple of weeks. “The Weekly Bioanalysis” is brought to you by KCAS Bio.KCAS Bio is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the pharmaceutical, biopharmaceutical, animal health and medical device industries.

    One & Done Therapies: The Landscape of Gene Therapy for Conditions

    Play Episode Listen Later Jul 28, 2024 80:09


    The most recent episode of "The Weekly Bioanalysis" podcast is all about genes today! The topic was originally inspired by an article entitled "The Coming of Age of One-and-Done Therapies" which jumped out to both of our hosts, Dom and John, and had been on the back burner for a while for them to discuss. With KCAS Bio housing entire departments specializing in bioanalysis, and given the recent rise of similar topics in the news, this seemed like the right time for the guys to chat about it.“The Weekly Bioanalysis” is a podcast dedicated to discussing bioanalytical news, tools and services related to the pharmaceutical, biopharmaceutical and biomarker industries. Every month, KCAS Bio will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the bioanalytical world the past couple of weeks. “The Weekly Bioanalysis” is brought to you by KCAS Bio.KCAS Bio is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the pharmaceutical, biopharmaceutical, animal health and medical device industries.

    Offering Global Services: Latest News from Lyon and Melbourne

    Play Episode Listen Later Jun 28, 2024 82:04


    Dom has been globe-trotting lately, and he has come back to report in on his adventures with John, as they discuss our global services here at KCAS Bio. They talk about the updates and the latest news from Lyon and the rollout of our collaboration with Crux Laboratories in Melbourne. Most notable was Dom's trip to Lyon and some of the excitement he experienced there (spoiler: it involves tear gas!!). Our two hosts also discuss the strategy and growth of both our Lyon site, and the new things happening with our collaboration site in Australia. Lots to cover – should be a fun and entertaining episode of the podcast!“The Weekly Bioanalysis” is a podcast dedicated to discussing bioanalytical news, tools and services related to the pharmaceutical, biopharmaceutical and biomarker industries. Every month, KCAS Bio will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the bioanalytical world the past couple of weeks. “The Weekly Bioanalysis” is brought to you by KCAS Bio.KCAS Bio is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the pharmaceutical, biopharmaceutical, animal health and medical device industries.

    Non-GLP Studies from Early PK to Readiness for GLP Tox Studies

    Play Episode Listen Later May 28, 2024 90:42


    Dom and John welcome special guests, Habibi Goudarzi and Rochelle Burke to episode #77 of "The Weekly Bioanalysis", where they discuss the progression of bioanalytical needs for non-GLP Studies, from Early PK to readiness for GLP Tox Studies. These specialists from the KCAS Bio team begin with an introduction to all things non-GLP and LC-MS. From there, they discuss the general need for speed and the workflow they have established at KCAS Bio to facilitate rapid turnaround for studies, as well as some of the challenges that can be an obstacle to the speed of studies (issues with tissue analysis, sample size, etc). The four go on to discuss the trends they have seen taking place within LC-MS and the future expectations they have for non-GLP LC-MS/MS.“The Weekly Bioanalysis” is a podcast dedicated to discussing bioanalytical news, tools and services related to the pharmaceutical, biopharmaceutical and biomarker industries. Every month, KCAS Bio will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the bioanalytical world the past couple of weeks. “The Weekly Bioanalysis” is brought to you by KCAS Bio. KCAS Bio is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the pharmaceutical, biopharmaceutical, animal health and medical device industries.

    GLP-1 Analogues: Blockbuster Drugs - Applications & Challenges

    Play Episode Listen Later Apr 28, 2024 85:52


    For episode #76 of "The Weekly Bioanalysis", Dom and John talk about the popular topic of GLP-1 Analogues - these series of recent blockbuster drugs with multiple applications, as well as some of their bioanalytical challenges. First, the guys go over a little bit of the mechanism of action of GLP-1's, then some of the rules around them and their initial diabetic treatments. They talk about the structures, and a little bit about how they are being used in weight loss (which, of course, is how these drugs have become so popular in mainstream culture now). Finally, they will discuss some of the resulting supply chain issues and even some of the bioanalytical challenges and what the future of these GLP-1 Analogues might be. It's a jam packed show - really an interesting, fascinating topic the guys enjoy discussing. “The Weekly Bioanalysis” is a podcast dedicated to discussing bioanalytical news, tools and services related to the pharmaceutical, biopharmaceutical and biomarker industries. Every month, KCAS Bio will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the bioanalytical world the past couple of weeks. “The Weekly Bioanalysis” is brought to you by KCAS Bio. KCAS Bio is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the pharmaceutical, biopharmaceutical, animal health and medical device industries. 

    Rebranding KCAS Bio: Next Steps to an Integrated Future

    Play Episode Listen Later Mar 28, 2024 63:05


    CEO of KCAS Bio, John Bucksath, joins Dom and John for a special 75th episode of “The Weekly Bioanalysis” podcast, and he is absolutely delighted to use the special episode to talk about the recent rebrand of KCAS to KCAS Bio! Mr Bucksath and our hosts discuss the reason the rebrand came about, the process our organization took, and some of the initial reactions our team have experienced from our first few outings with the new look and name. Join us as we introduce the new brand and point to it as the first of many steps into the future of our organization!“The Weekly Bioanalysis” is a podcast dedicated to discussing bioanalytical news, tools and services related to the pharmaceutical, biopharmaceutical and biomarker industries. Every month, KCAS Bio will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the bioanalytical world the past couple of weeks. “The Weekly Bioanalysis” is brought to you by KCAS Bio.KCAS Bio is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the pharmaceutical, biopharmaceutical, animal health and medical device industries.

    Addressing the Needs of Rare Diseases: Challenges & Trends

    Play Episode Listen Later Feb 28, 2024 73:14


    During this episode of “The Weekly Bioanalysis”, Dom and John talk about addressing the needs of rare diseases - some challenges and industry trends they've watched take place, and they are joined by guest, Lindsay Rutherford, who has her own personal experience with rare disease and how it can impact lives. As a bioanalytical provider, KCAS Bio of course has a unique take on this topic as well, as rare disease has its own challenges in terms of small sample loads, rapid turnaround of samples to get results out to pharma companies, lack of matrix, etc.“The Weekly Bioanalysis” is a podcast dedicated to discussing bioanalytical news, tools and services related to the pharmaceutical, biopharmaceutical and biomarker industries. Every month, KCAS Bio will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the bioanalytical world the past couple of weeks. “The Weekly Bioanalysis” is brought to you by KCAS Bio.KCAS Bio is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the pharmaceutical, biopharmaceutical, animal health and medical device industries.

    The Parallel Evolution of the Bioanalytical Industry and KCAS

    Play Episode Listen Later Jan 28, 2024 70:40


    To kick off the first episode of “The Weekly Bioanalysis” in 2024, Dom and John unveil some fun new things happening at KCAS, by talking about the parallel evolution of the bioanalytical industry and KCAS. Our hosts go way back – almost to “square one” (discussing “What is bioanalysis?” and “How has bioanalysis changed over the years?”. They take a nice little dip back into history and then and then tie it all back to where we are now and what it means about we are going for the future. We hope you enjoy our announcement as much as you enjoy listening to how we've evolved as an industry, as well as an organization.“The Weekly Bioanalysis” is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    Introduction to Scientific Advisor Team and Recap of 2023

    Play Episode Listen Later Dec 28, 2023 76:54


    For the final episode of “The Weekly Bioanalysis” in 2023, Dom and John invited KCAS's scientific advisory team to join them, as we thought that as we are coming to the end of the year, it might be a good opportunity to introduce a few members of the scientific advisory team who may be involved in some greater capacity with the podcast going forward, as the organization grows and expands. Then our hosts just have a chat about reviewing how 2023 went and what they see coming up in 2024 within the pharmaceutical and biopharmaceutical industries – so a look back, a look at where we are, and a look forward.“The Weekly Bioanalysis” is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    Drug Development and Where Bioanalytical Fits In

    Play Episode Listen Later Nov 28, 2023 77:50


    Dom and John have been doing this for a long time (for over 70 episodes now, to be exact), but they felt it might be a good idea to jump back to the very beginning and discuss the overarching concept of the Drug Development process and where it is that Bioanalysis fits in. This is somewhat of a response to a recent listener request, but we also feel its important every once in a while to refocus and put all of the things we do at KCAS into perspective against the entire pharmaceutical and biotech industry – from large and small molecule and GLP vs Non-GLP, to all the therapeutic areas with drug development, Dom and John discuss it all on episode #71 of “The Weekly Bioanalysis”"The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    Looking Forward to the 2023 Autumn Conference Season

    Play Episode Listen Later Sep 28, 2023 68:46


    It is that time of year once again... the Fall Conference Season! Every industry has its own set of important trade shows and meetings, but for the Pharma, biotech and bioanalytical industries, these conferences are an opportunity for the planet's leading experts to get together and share the newest ways to heal the world. With October almost upon us, Dom and John discuss the upcoming conferences in our industry, and why it might be worth your time to find yourself at more than one of them - it might even be a chance to meet Dom and John there!"The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    The Evolving World of Antibody-Drug Conjugates and How KCAS Can Help

    Play Episode Listen Later Aug 29, 2023 80:46


    Starting off with a description of Antibody Drug Conjugates (or ADCs, for short), Dom and John dive into this field of the industry and discuss the ways these services have changed over time and even how they've changed recently. They review the role of ADCs in meeting some of the unmet medical needs in oncology and the way they're changing the effectiveness of some of the most modern drugs being developed. The evolution of ADC design for approved medications and indications make it clear that Antibody Drug Conjugates will be a big part of our industry for a long time."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    Molecular Cell & Gene Therapy, with Special Guest Carrie Vyhlidal, PhD

    Play Episode Listen Later Jun 28, 2023 87:32


    Special guest Carrie Vyhlidal, PhD of KCAS joins John and Dom in the 68th episode of "The Weekly Bioanalysis" to discuss the ways molecular cell & gene therapy services has evolved and why their role will likely become more and more important to the world of bioanalytical drug development in the future. They discuss everything from the history of Cell & Gene Therapies and the topic of replicates, to some of the challenges and pitfalls of GLP research for molecular cell & gene therapy specialists."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    Evolution of PK Modalities & the Impact on Regulations

    Play Episode Listen Later Apr 28, 2023 65:42


    In the world of bioanalysis, pharmacokinetics is a key step in the process of measuring and identifying elements of the drug. It is a baseline for sample analysis, and in episode 67 of "The Weekly Bioanalysis", Dom and John discuss the history and evolution drug and pharmacokinetic modalities and the impact on regulations."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, Milan, Italy, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    Recent Advances in Hybrid LC-MS/MS (w/ guests Dawn Dufield and Barry Jones)

    Play Episode Listen Later Mar 24, 2023 108:25


    Special guests Dawn Duffield, PhD of KCAS and Barry Jones, PhD of Crinetics join John and Dom in the 66th episode of "The Weekly Bioanalysis" to discuss the ways Hybrid LC-MS/MS has advanced in recent years and how the technology has gone from "new" and somewhat obscure to much more mainstream as a leading option for program success within the pharmaceutical and biopharmaceutical industries."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, Milan, Italy, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    Early Non-clinical Bioanalysis Plays in Your Project

    Play Episode Listen Later Feb 28, 2023 78:25


    Dom and John discuss the role early non-clinical bio analysis plays in your project, why it is important, how it has changed over the years, and what might be next for this growing part of the industry."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, Milan, Italy, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    A Review of 2022's "Fierce 15" and What it Means for 2023

    Play Episode Listen Later Jan 27, 2023 83:57


    In what is becoming an annual tradition here on “The Weekly Bioanalysis” podcast, Dom and John take a bit of time to take a look back at 2022's Fierce 15 (the annual selected list of impressively performing companies across the biotech world, highlighting a broad range of teams, leaders and science, as selected by the Fierce Biotech group). In addition to this, the guys discuss the list of drugs that received approvals throughout 2022, then they discuss the trends they see emerging from these industry lists… and what it means as we begin 2023."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, Milan, Italy, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    A Look Back at 2022 While Looking Ahead to 2023 at KCAS

    Play Episode Listen Later Dec 29, 2022 86:00


    It has been an extremely transformative year for KCAS in 2022. As we approach the beginning of 2023, Dom and John take a moment during episode #63 to look back at all the changes and evolutionary growth that has transpired around the organization (and around the world, as we now have multiple European footprints as well as US locations). They go into detail about the opportunities these changes have allowed for our customers throughout 2022, as well as what it now means for the pharma and biopharma industry as we move forward into 2023."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA, Milan, Italy, and Lyon, France, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    An Introduction to Active Biomarkers, with Special Guests John Bucksath and Marc Essodaigui

    Play Episode Listen Later Nov 30, 2022 77:40


    Special guests John Bucksath, CEO of KCAS in Olathe, KS and Marc Essodaigui, General Manager of Active Biomarkers in Lyon, France, join Dom and John this week as they introduce our listeners to Active Biomarkers – the most recent acquisition of KCAS in the European space. The gentlemen discuss a brief history of Active Biomarkers, the path to their acquisition by KCAS, and what it now means – for both the organizations as well as their customers and the industry – now that these two CROs have come together to couple their skillsets."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA and Milan, Italy, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    The 2022 Pharma/Biopharma Trade Show & Conference Season

    Play Episode Listen Later Oct 31, 2022 80:23


    Every year, beginning in late August, with the summer over and everyone settling back into a normal routine, the entire industry begins preparing itself for the conference and trade show season. These events serve as a source for new business in some cases, of course, but they also serve as an opportunity for like-minded scientists and industry leaders to discuss their findings and discoveries over the past year and gauge which direction the industry might be going in the year ahead. This episode, Dom and John discuss the 2022 conference season and where you can find KCAS if you want to see them!"The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA and Milan, Italy, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    Clinical Sample Kitting: Personal Touch Drives Success

    Play Episode Listen Later Sep 30, 2022 60:08


    Clinical Sample Kitting and Sample Storage have played vital roles in the pharmaceutical and Biopharmaceutical industry for decades, but KCAS began offering the services in the early 1990s in response to shortcomings observed in the collection techniques in trials where we were providing bioanalytical support. During episode #60 of "The Weekly Bioanalysis" podcast, John Pirro and John Perkins host two guests from the Clinical Sample Kitting team who discuss the role these services play in the bioanalytical process."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA and Milan, Italy, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    Intro to John Pirro, His New SSA Role, and What's Next for the LBA Team

    Play Episode Listen Later Aug 26, 2022 87:42


    For the 59th episode of KCAS's podcast, Dom and John are excited to welcome a special guest to the show! John Pirro has been a team member for years now at KCAS, but he joins “The Weekly Bioanalysis” this episode to showcase the changes involved in his new SSA (Senior Scientific Advisor) role, and the team talks a bit about what this means for KCAS's clients' projects – especially our Ligand Binding Assay. So join us in welcoming John into this new role and learn a bit about the fun things that the KCAS LBA has for the future!"The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA and Milan, Italy, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    The Evolution of Drug Design and Its Impact on Bioanalysis (Part 2)

    Play Episode Listen Later Jul 29, 2022 87:35


    In this 58th episode of "The Weekly Bioanalysis" podcast, Dom and John wrap up their 2-part series on the Evolution of Bioanalysis, as they dive into the history of their bioanalysis careers by reviewing Drug Design and Development, and how that has effected the things CROs like KCAS do today. They discuss where the pharmaceutical and biopharmaceutical industry has been, and work their from 2010 or so to the modern day lab space - and even a bit on what the future may hold in the space."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA and Milan, Italy, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    The Evolution of Drug Design and Its Impact on Bioanalysis (Part 1)

    Play Episode Listen Later Jun 24, 2022 78:02


    During the 57th episode of "The Weekly Bioanalysis" podcast, Dom and John have a chance to dive into their history of their bioanalysis careers by reviewing the evolution of Drug Design and Development, and how that has effected the things CROs like KCAS do today. They discuss where the pharmaceutical and biopharmaceutical industry has been, and work their way through to roughly 2010 or so by the end of this multi-part series (check back soon for the continued episodes as they move their way into the present day)."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA and Milan, Italy, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    Discussing Cell & Gene Therapy Services with Jeff Hester, PhD

    Play Episode Listen Later May 25, 2022 74:31


    For the 56th episode of “The Weekly Bioanalysis” podcast, the Senior Director of Cell & Gene Therapy Services at KCAS, Jeff Hester, PhD, joins Dom and John to discuss the growing field of Cell & Gene Therapy. Cell and gene therapies (CGTs) are types of treatment that use cellular or genetic material with the goal of treating a disease or a disorder. Often it can be a combination of cell and gene therapies, which is the case for chimeric antigen receptor T (CAR T) cells. Jeff explains what KCAS has done in putting together a high-quality team of experts offering these services and what it means for your drug development projects."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA and Milan, Italy, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    Building For the Future: New Investments in KCAS

    Play Episode Listen Later Apr 23, 2022 80:37


    Even while many in the industry have pulled back on growth and expansion efforts after COVID's years-long effect on business and supply lines worldwide, KCAS is in a unique position - as a result of many years of sound decision making and customer relationship building - to expand its operations into an all-new facility full of state-of-the-art equipment and technology throughout. During this month's episode of podcast, Dom and John talk a bit about what everyone can expect as they see KCAS move into these beautiful new facilities during the summer of 2022!"The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 250 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA and Milan, Italy, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    Renold Capocasale (Vice Chair and Founder of FlowMetric) Joins as Our Guest!

    Play Episode Listen Later Feb 28, 2022 94:47


    Earlier this month, KCAS announced the acquisition of FlowMetric, LLC, a leading provider of flow cytometry and cellular assay R&D services to biotech, pharmaceutical and cell/gene therapy industries. With the KCAS family growing, Dom and John took the opportunity to invite Renold Capocasale, the Vice Chair and Founder of FlowMetric, to join the podcast for episode #54 to discuss what the recent union of the organizations means for KCAS now that the combined companies are positioned to continue growing operations in Kansas City, Doylestown, PA and Milan, Italy."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 200 talented and dedicated individuals with growing operations in Kansas City, Doylestown, PA and Milan, Italy, where we are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    What Role Can Bioanalysis Play in Your Drug Development Project?

    Play Episode Listen Later Jan 25, 2022 88:12


    For the first episode of “the Weekly Bioanalysis” in 2022 (also the first episode of our “second season” of the podcast), Dom and John speak to a topic that is near and dear to their hearts: The role Bioanalysis plays in your projects. KCAS offers so many services, but as technologies and discoveries within the industry advance, it is important to understand the ways each type of service can help you in the development of your project. The guys start by defining each phase of development (beginning with discovery/preclinical) and they pinpoint the bioanalytical services available within each phase."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Once per month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 200 talented and dedicated individuals who are committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    News and Q&A About the New COVID Variant: OMICRON

    Play Episode Listen Later Dec 23, 2021 56:25


    As most Americans were wrapping up their Thanksgiving and Black Friday rituals just a few weeks ago, many felt the corner had finally been turned on COVID and we would all be able to start finally getting back to normal… instead, within days, we were all greeted with news about a new mutation of the COVID-19 virus that had been detected by scientists in Johannesburg. With so many concerns lingering as we now go into the holiday season with yet another potentially dangerous variant, Dom and John devote episode #52 of “the Weekly Bioanalysis” to reviewing the brief history of Omicron, the facts we know about Omicron so far, and the rest of the episode is devoted to “feedback from fans” as they answer a number of Omicron-related questions."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Twice every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 150 talented and dedicated individuals committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    Small Molecules: New Agents Coming for COVID Patients

    Play Episode Listen Later Nov 20, 2021 92:04


    Although the world now has a number of vaccines in place and available to serve as a preventative and/or impact-reduction method for COVID, there are a number of reasons that it is also important for the Pharma and Biopharma industries to continue developing other treatment and medicines to for those who become infected - with or without having taken the vaccine. Lucky for all of us, there are a few small molecule agents coming available for COVID patients in 2022, and during episode 51 of "The Weekly Bioanalysis", John and Dom discuss all the small molecule drugs being developed to meet these needs."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Twice every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 150 talented and dedicated individuals committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    Special 50th Episode - LIVE, Together, and "Face-to-Face" for the First Time!!

    Play Episode Listen Later Oct 29, 2021 50:36


    It's an extra special episode of “The Weekly Bioanalysis” as Dom and John celebrate the 50th EPISODE of the official KCAS Podcast by greeting you LIVE in front of the cameras in person for the first time! To watch the video version of the episode, visit this link on KCAS's website: https://kcasbio.com/blog/twb-050As usual, they discuss the news, the industry, and other topics like their recent trip to AAPS in Philadelphia… but for the first time since we began the podcast, they will do it all as they sit right next to one another and talk to YOU “face to face”. Enjoy this special episode – we hope you enjoy watching it as much as we enjoyed producing it together!"The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Twice every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 150 talented and dedicated individuals committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    Sonia Hall, PhD (CEO of BioKansas) Joins as Our Guest for Episode 49!

    Play Episode Listen Later Oct 26, 2021 86:50


    Sonia Hall, PhD, the CEO of BioKansas, joins Dom and John as our guest for the 49th episode of "The Weekly Bioanalysis". Among a litany of topics, Sonia takes the time to tell the guys about all the amazing things BioKansas does and she gives a breakdown of the many upcoming events planned for the next few months. Both Dom and John are big fans of BioKansas and you can just tell in their voices that they're excited for all the things 2022 sounds like it will bring from Sonia and her team!"The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Twice every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks. The Weekly Bioanalysis is brought to you by KCAS.KCAS is a progressive growing contract research organization of well over 150 talented and dedicated individuals committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    Antibody-Drug Conjugates: The Combination of Targeted Delivery + Potent Treatment

    Play Episode Listen Later Oct 26, 2021 96:53


    This episode Don and John thought they would talk about something near and dear to our hearts here at KCAS - Antibody-Drug Conjugates. Increasingly we've all experienced talk about ADCs everywhere being approved and for various conditions - mostly oncology (drugs used in the treatment of cancer). And of course the point of an ADC is to use the ability of the antibody to deliver an otherwise very toxic drug to the area of interest as safely as possible. KCAS has supported multiple ADC studies both in the Pharmaceutical and Biopharmaceutical devisions, so Dom and John were really excited about this one!"The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Twice every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks.The Weekly Bioanalysis is brought to you by KCAS. KCAS is a progressive growing contract research organization of well over 150 talented and dedicated individuals committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    Official Vaccine Approval! How We Got Here and What It Means Next

    Play Episode Listen Later Sep 3, 2021 90:34


    One of the biggest questions on so many people's minds since the beginning of 2020 has been “how long will it take for an official vaccine to be approved by the FDA?”. It seems the answer has arrived in the form of the approval by the FDA for Pfizer's COVID-19 Vaccine. Of course, the same vaccine (as well as a number of others) have already been in use for months now, so what exactly is the difference now, and what does it mean moving forward? Dom and John discuss these items – among others – as we all celebrate another impressive achievement within the scientific world on this long road we've all been on together."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Twice every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks.The Weekly Bioanalysis is brought to you by KCAS. KCAS is a progressive growing contract research organization of well over 150 talented and dedicated individuals committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    All the News From Around the Pharma and Biopharma Industry, end of Summer of 2021

    Play Episode Listen Later Aug 27, 2021 45:19


    Dom and John have had a busy summer, and due to recent pressing issues, episode #46 of “The Weekly Bioanlaysis” is an abbreviated version, focusing only on a review of recent news and resources within the industry. Our next episode #47 will focus on the recent announcement that Pfizer's COVID vaccine has been officially approved by the FDA. Please come back and check that one out – and as always – please continue sending your thoughts, feedback and ideas for podcast episode topics!"The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Twice every month, KCAS will bring you another 60 minutes (or so) of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks.The Weekly Bioanalysis is brought to you by KCAS. KCAS is a progressive growing contract research organization of well over 150 talented and dedicated individuals committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    The Value of a Dedicated Program Management Team at Your CRO

    Play Episode Listen Later Aug 4, 2021 84:23


    Dom and John often like to feature each of the groups within our industry that contribute to the success of the team, and recently, one of those groups that they were asked about was Program Management. Both of them see first hand the benefit of having a dedicated program management team at a CRO like KCAS, and while we have often showcased others within our organization, it felt like it was time to shine a light on a too often unsung hero of customer relationships. For this episode, Dom and John invite Chris Young, the director of KCAS's Program Management team, to join them as we discuss the role his team plays and why it is so important."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Twice every month, KCAS will bring you another 45-60 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and discuss what they've learned about the Bioanalytical world the past couple of weeks.The Weekly Bioanalysis is brought to you by KCAS. KCAS is a progressive growing contract research organization of well over 150 talented and dedicated individuals committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    Evolving Challenges of COVID with the Emergence of the Delta Variant

    Play Episode Listen Later Jul 27, 2021 68:37


    A number of COVID variants have popped up throughout the life of our podcast, but we're all hearing more and more stories coming out about the struggles and new challenges surrounding the Delta variant. Despite the encouraging rise in the number of vaccinated, a number of countries have seen an alarming spread of the Delta variant, leading to concern around the globe. For episode #44 of “The Weekly Bioanalysis”, Dom and John thought they would discuss basic virus mutation, how we measure transmissibility, the way variants progress (and why), and what we all should continue to expect in a world of new COVID variants."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Twice every month, KCAS will bring you another 45-60 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the past week.The Weekly Bioanalysis is brought to you by KCAS. KCAS is a progressive growing contract research organization of well over 150 talented and dedicated individuals committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    Mainly News Episode: The Latest on Coronavirus and Everything Else Bioanalytical

    Play Episode Listen Later Jul 26, 2021 44:42


    Apologies from the Producer for the shorter length of this episode. We had planned to air a recorded podcast episode on a topic we already knew had the potential to become somewhat controversial, but as the news on this topic progressed between the time of recording and publishing of this episode, we all felt the nature of the material was best left shelved – at least for the moment. Perhaps someday we will publish the “full” episode #43 of “The Weekly Bioanalysis”, but for now it will remain a “News and Updates” episode from Dom and John."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 45-60 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the past week.The Weekly Bioanalysis is brought to you by KCAS. KCAS is a progressive growing contract research organization of well over 100 talented and dedicated individuals committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    The State of Play with Vaccines: The Upcoming and the Next Generations

    Play Episode Listen Later Jun 28, 2021 80:46


    As more and more of America (and the world) become fully vaccinated, there are still many questions from everyone, regardless of whether they have been vaccinated. For the 42nd episode of “The Weekly Bioanalysis” podcast, Dom and John discuss many of these questions by giving a sort of “State of Play” with COVID vaccines, as well as looking ahead at what's next for Vaccines – and even what the “next generation” of vaccines might look like with so many around the globe forming a different perception about them."The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 45-60 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the past week.The Weekly Bioanalysis is brought to you by KCAS. KCAS is a progressive growing contract research organization of well over 100 talented and dedicated individuals committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

    The Need for Regulation and Oversight in the Pharma and Biopharma Industries

    Play Episode Listen Later Jun 26, 2021 75:51


    During episode #41 of “The Weekly Bioanalysis”, Dom and John discuss the often sensitive topic of the need for regulation and oversight within the pharma and biopharma industries during testing, manufacturing and clinical trials. The evidence for these things has been made clear many times over the years, but even within the past few weeks, there have been news stories that continue to showcase the importance of having systems in place that ensure all parties involved are following proper and safe procedures that can be monitored and verified.

    Trends in the Pharma Industry (post-COVID) and What It Means for KCAS

    Play Episode Listen Later Jun 26, 2021 73:03


    2020 had an impact on nearly every industry around the world in 2021, with effects that will likely continue to ripple well into 2022 and possibly the years beyond. Arguably one of the industries that saw the largest shifts related directly to the events of 2020 were the Pharma and Biopharma sectors. From public perception to investor interest, the unprecedented events had a number of impacts on our industries. To celebrate the 40th episode of "The Weekly Bioanalysis", Dom and John are joined by the CEO of KCAS, John Bucksath, to discuss these impacts and specifically the changes we've experienced here at KCAS within the last year or so, and what it means for the years to come!

    Explaining the Role of Bioanalysis: Questions from a "Beginner"

    Play Episode Listen Later Apr 28, 2021 87:13


    During episode 39 of "The Weekly Bioanalysis", Dom and John are joined by one of our KCAS colleagues, Mallory Jolly. Mallory is our newest Business Development Representatives, and while she has an extensive background within the industry, she found it occasionally difficult to describe the nuances and particulars that set Bioanalysis apart from the rest of the Pharma and Biopharma industry. As she occasionally brought this up in conversations, she found that even some industry veterans and CEOs would admit they felt the same about the role Bioanalysis plays in drug development. Learning this, Mallory approached John and Dom about discussing these things on the Podcast - so that's exactly what they do here!"The Weekly Bioanalysis" is a podcast dedicated to discussing Bioanalytical news, tools and services related to the Pharmaceutical, Biopharmaceutical and Biomarker industries. Every week, KCAS will bring you another 45-60 minutes of friendly banter between our two finest Senior Scientific Advisors as they chat over coffee and brief themselves on what they've learned about the Bioanalytical world the past week.The Weekly Bioanalysis is brought to you by KCAS. KCAS is a progressive growing contract research organization of well over 100 talented and dedicated individuals committed to serving our clients and improving health worldwide. Our experienced scientists provide stand-alone bioanalytical services to the Pharmaceutical, Biopharmaceutical, Animal Health and Medical Device industries.

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