Podcasts about Molecule

In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Ankit Gupta, CEO at Tenshi Kaizen. Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with Ankit, covering: His accidental journey into pharma, and then pharma manufacturing How his exposure to the pharma value chain via consulting led to numerous roles in the sector, including a critical one at Strides Pharma Sciences Limited and other group companies held by the founders The honour of being appointed CEO at Tenshi, and building out InstaPill(R) - its proprietary oral drug delivery technology - from incubation to growth Why India is poised for growth now that it's leading the 'D' as well as the 'M' of CDMO The lay of the land in India's biopharma and pharma ecosystem Ankit Gupta is a seasoned finance and strategy leader with close to 15 years of experience in the pharmaceutical and biotechnology sectors. At Tenshi Kaizen, he leads the development and global expansion of innovative pharmaceutical technology platforms, including the flagship InstaPill. He also serves as the Chief Corporate Strategy & Development Officer across all group entities promoted by the founders. Ankit is known for his expertise in corporate strategy, growth acceleration, and business transformation. In his prior role as Vice President – Strategy and Corporate Development at Gland Pharma Limited and Strides Group, he played a pivotal role in long-range planning, financial forecasting, and strategic initiatives that contributed to the Strides Group turnaround in the financial year 2022-2023. He brings deep experience in both organic and inorganic growth, asset optimization, and risk management. A gold medalist in MBA (Finance), Ankit also holds global certifications in corporate finance, private equity, valuations, business leadership, and strategy, bringing a rare blend of financial precision and strategic foresight to the group's leadership. Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space.  We'd also appreciate a positive rating!  Molecule to Market is also sponsored and funded by ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.

How long - and healthy - will we live? Can we slow the aging process? What is NAD and why is there so much buzz around it? Unlock the secrets of longevity science with Dr. Andrew Salzman!  Try Wonderfeel: Use code DRMOTLEY till August 5th to subscribe & save $15 off the one-time price, and bank a $20 credit for your next subscription delivery! Homepage: https://tidd.ly/451qetX Wonderfeel Youngr™ NMN product page: https://tidd.ly/41i4APx   Wonderfeel NMN Capsuls™ product page: https://tidd.ly/3UlVKwB Want more of The Ancient Health Podcast? Subscribe to the YouTube channel. Follow Dr. Motley! Instagram Twitter Facebook Tik-Tok Website ------   Do you have a ton more in-depth questions for Doctor Motley? Are you a health coach looking for more valuable resources and wisdom? Join his membership for courses full of his expertise and clinical wisdom, plus bring all your questions to his weekly lives! Try it FREE for 15 days here: doctormotley.com/15 *  If you're looking for a safe, easy, natural way to improve your heart health, check out zona.com and use code DRMOTLEY for $100 off the Zona Plus device! 

In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Adam Sherlock, CEO at Qinecsa. Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with Adam, covering: How he developed his professional CEO skills over the years to complement is entrepreneurial spirit The combination of micro and macro factors that help determine when the right time is to go to market, and sell The importance of your gut instinct when assessing M&A targets... and painting a picture of why the world is a better place when together Several attempts at failing to retire... and being tempted back into another pharma services CEO role How R&D services will be impacted by AI, and why we all need to be eating our own lunch Adam is a serial entrepreneur and executive leader with nearly 40 years of experience in the international life sciences industry, particularly in bio/pharma, IVD, and medical device sectors. A scientist by training, he has led successful growth and M&A efforts, creating exceptional value in four private equity-backed businesses over the past decade.  Adam is also a sought-after NED, Chair, and independent advisor. Currently, he serves as CEO of Qinecsa, a global provider of pharmacovigilance technology and services. Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating! Molecule to Market is also sponsored by Bora Pharma (boracdmo.com) and Charles River (www.criver.com), and supported by ramarketing.

Why do we always want more, even when we know it won't make us happy? In this episode, I speak with Michael Long, co-author of The Molecule of More and author of Taming the Molecule of More, about the true nature of dopamine, craving, and how to reclaim our power from the constant chase for the next hit—whether it's drugs, sugar, social media, or even achievement. We explore: The surprising truth about what dopamine actually does Why the feeling of “wanting” hijacks the brain—and how it relates to addiction How GLP-1 medications (like semaglutide) may help reduce cravings—and why they're not a magic fix The 6 tools from ACT (Acceptance & Commitment Therapy) that help us create space between craving and choice What Victor Frankl got right about meaning—and how to find your own Why "enoughness" in the present moment is the antidote to always wanting more If you struggle with addiction, compulsive behavior, or the nagging sense that you're never quite satisfied—this episode offers insight, hope, and actionable tools to reclaim peace, purpose, and presence.

In this conversation, Chris Burres discusses the unique benefits of ESS 60, a Nobel Prize-winning molecule known for its potential in extending life and improving health. He explains the science behind its effectiveness, particularly in relation to oxidative stress and mitochondrial health. The discussion also covers practical advice on dosing, timing, and the benefits of different oil carriers for ESS 60. Chris shares anecdotal evidence regarding its effects on sleep, dreams, and overall wellness, while also addressing the importance of being proactive about health and longevity. The conversation concludes with insights into the future of longevity research and common myths surrounding it.Chapters00:00 Introduction to ESS 60 and Longevity02:31 Understanding the Unique Benefits of ESS 6006:42 Comparing Olive Oil and MCT Oil for Health Benefits11:27 Dosing Strategies and Saturation Points16:11 Timing and Circadian Rhythms in Supplementation26:20 Anecdotal Evidence and Cancer Research30:45 Exploring Longevity Practices and Habits31:37 Relaunching the Longevity Summit32:37 The Journey of Interviewing Experts34:27 The Search for Longevity Solutions35:24 Understanding Stem Cells and Longevity39:31 The Future of Longevity Research40:48 Expert Insights on Lifespan46:04 Debunking Longevity Myths51:14 Taking Charge of Your Health

"Wir haben genug Abba gehört" – erzählt Ora the Molecule in einem Interview über ihre Anfänge als DJ. Die scheinbar immer gleichen Playlists auf den Parties in Oslo versucht sie mit ihren eigenen Vorstellungen aufzumischen und beginnt so letztlich selbst Tracks zu bauen. Inspiriert von den Sounds der 70er Jahre und Disco-Größen wie der Italienerin Raffaela Carrá, hat Ora the Molecule nun ihr zweites Album "Dance Therapy" veröffentlicht. Sie ist Norwegens Disco-Queen! Ora the Molecule hat in der Band von Hubbabubbaclub die Synthies gespielt, ihre Tracks mischt Prins Thomas. Jeder kennt sich in der kleinen norwegischen Szene, in der Nora Schjelderup konsequent versucht etwas anders zu machen: die Disco-Vibes wieder auf den Dancefloor zu bringen. Während auf dem Vorgänger unklar war, ob Ora the Molecule eigentlich ein Trio ist, oder die Solo-Vision von Nora Schjelderup, wurde mit der Zeit immer klarer, das es sich um letztere handelt. Im Gegensatz zu ihrem Debüt ("Human Safari") verkörpere "Dance Therapy" also vielmehr ihren eigenen, futuristischen Dance Style. "Es fühlt sich an, als wäre das nun mein Debüt", erklärt Schjelderup, die sich ihr eigenes Studio in einer Hütte außerhalb von Oslo eingerichtet hat und was sie zum Beispiel im Track "Becoming Ora" direkt thematisiert: "I moved into a cabin / Into the woods / Cause I was devouring the world around me / I wanted to be everything at once / I wanted to be everywhere / And I loved everyone."

What if one molecule could help you live longer, think clearer, and recover faster — and it's backed by a Nobel Prize?   In this episode of the Thrive State Podcast, Dr. Kien Vuu (Doctor V) sits down with Chris Burres, research scientist and founder of MyVitalC, to unpack the science behind Carbon 60 (C60) — a molecule so powerful it increased the lifespan of test rats by 90% in a peer-reviewed study.   Chris breaks down the connection between oxidative stress, aging, and how ESS60 (a purified version of C60) could be the key to unlocking greater human performance, mental clarity, and cellular longevity.  

In this special episode of Molecule to Market, recorded at this year's CDMO Live in Rotterdam, industry leaders come together to assess the evolving state of the contract development and manufacturing sector. Raman is the panel moderator, joined by:  Gil Roth - PBOA Dr. Jim Li - BioDuro Sundia Kaan-Fabian Kekec - Simon-Kucher They unpack cautious optimism in the face of lingering market uncertainties and geopolitical tension, you'll hear: How CDMOs are adapting to early-stage funding strain and evolving pricing models The impact of rising interest rates, tariffs, and global trade policy on pharma outsourcing Capacity and talent constraints facing CDMOs in new therapeutic modalities Why integrated models and scenario planning are key to future-proofing operations This episode offers timely insight into the challenges and opportunities shaping the next phase of growth for CDMOs worldwide. Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating! Molecule to Market is also sponsored by Bora Pharma (boracdmo.com) and Charles River (www.criver.com), and supported by ramarketing.

What if the key to reversing high blood pressure, erectile dysfunction, insulin resistance, and even cognitive decline wasn't a drug—but a molecule your body used to make naturally?

Benji explains how Pump Science leverages blockchain and cryptocurrency to revolutionize the search for longevity supplements. By using an automated, standardized process, Pump Science efficiently funds research and collects robust data to accelerate the discovery and validation of effective supplements for extending healthspan

In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Hella Kohlhof, CSO at Immunic. Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with Hella, covering: How the 'waste of two molecules' led to the spin-out creation of Immunic Therapeutics. The perfect blend of a founding team willing to split responsibility, learn and have a go. Ending up as a Nasdaq-listed company via a reverse merger... and all the new challenges that came with it. Immunic's divide-and-conquer global outsourcing strategy, while retaining tight control. Examples of how geopolitical issues have impacted a biotech's growth. Hella leads the Immunic's scientific strategy, including mode of action research, preclinical studies, and biomarker development. Dr. Kohlhof brings deep expertise in immunology, oncology, and drug development, with previous roles at 4SC AG, where she led preclinical and clinical projects. She holds a doctorate in biology from Ludwig Maximilians University of Munich and completed her postdoc at the Helmholtz Centre, focusing on B cell development. She holds several patents, has co-authored numerous publications, and is a regular speaker at scientific and industry events. Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating! Molecule to Market is also sponsored and funded by ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.

All the neurochemicals in the brain have to do with life in the present. Except for one: dopamine. Dopamine is the one neurochemical that looks to the future. It anticipates what may be to come and drives you towards it.That can be a good thing — dopamine is one powerful motivator — but it also has its downsides. Here to help us understand how the most important chemical in the brain works and how to deal with its pitfalls is Michael Long. Michael is a trained physicist turned writer whose latest book is Taming the Molecule of More. Mike and I discuss how dopamine, for better and worse, makes you want what you don't have. He shares what causes low dopamine activity, how to know if you're experiencing it, and what increases dopamine. We then talk about how to deal with the consequences of dopamine in some of the scenarios in which it plays a role — like losing the spark in a relationship and getting stuck in a smartphone scroll habit — and why so much of taming dopamine comes down to living in the here and now. We end our conversation with why The Great Gatsby is really a novel about dopamine and the fundamental answer to not letting the dopamine chase lead you around.Resources Related to the PodcastMike's previous appearance on the AoM podcastAoM Article: How to Do a Dopamine ResetAoM Podcast #745: Do You Need to Take a Dopamine Fast?AoM Article: Your Life Explained Through DopamineConnect With Michael Long  Taming the Molecule website

In this episode of Partnering Leadership, Mahan Tavakoli speaks with Aidan McCullen, the host and founder of The Innovation Show and author of the book Undisruptable: A Mindset of Permanent Reinvention for Individuals, Organisations and Life. Aidan shares examples on how organizations and individuals can embrace reinvention in order to become undisruptable. Some highlights:● Aidan McCullen talks about the reason why most change initiatives fail.● The transformation of a caterpillar into a butterfly and lessons for leaders.● How Amazon reinvented a failed product and transformed it into a killer product.● Aidan McCullen shares how seeing life as cyclical rather than linear helps us with a reinvention mindset. Also mentioned in this episode:● Rita McGrath author of The end of competitive advantage and Seeing around corners● Scott D. Anthony author of The Little Black Book Of Innovation: How it works, How to do it and co-author of Eat, Sleep, Innovate: How to Make Creativity an Everyday Habit Inside Your Organization ● Daniel Z. Lieberman author of The Molecule of More● Robert Sapolsky author of Behave Buy Aidan McCullen's Book:  Undisruptable: A Mindset of Permanent Reinvention for Individuals, Organisations and Life         Connect with Aidan McCullen: Aidan McCullen @ theinnovationshow.ioAidan McCullen LinkedInConnect with Mahan Tavakoli: Mahan Tavakoli Website Mahan Tavakoli on LinkedIn Partnering Leadership Website

The psychic prediction that led to the launch of the UK's first Lactoferrin brand… and why you should add it to your shopping list.What do you do when your husband tells you your business isn't scalable and you know deep down he's right?For entrepreneur Stephanie Drax, hearing those words after pouring five years of her life into a business left her paralysed with fear. Suddenly, every self-doubt surfaced: Do I have any real skills? Have I wasted my time? Am I capable of building something that lasts?But instead of giving up, Stephanie leaned into the tenacity her husband saw in her and created an innovative new business.Why you should tune inIt all started when yet another cold swept through her household. Frustrated, she went searching for a real solution and stumbled upon lactoferrin – a ‘miracle molecule' found in colostrum, scientifically proven to be antiviral, antibacterial, anti-inflammatory, gut-enhancing, and immune-boosting.Today, Stephanie is the founder of Leapfrog Remedies, the first lactoferrin brand in the UK – and what's even wilder? A psychic predicted it all.

Story at-a-glance DMSO is an “umbrella remedy” capable of treating a wide range of challenging ailments due to its combination of therapeutic properties (e.g., reducing inflammation, improving circulation, and reviving dying cells) One of DMSO's unique properties is its ability to enter through the skin and carry anything it dissolves with it as it rapidly travels throughout the body, greatly enhancing the potency and viability of many pharmaceutical drugs Because of this, numerous preparations over the years have combined DMSO with a commonly used medication, and in many cases, demonstrated safety and efficacy of the combination to drug regulators Some of these DMSO combination therapies are able to treat challenging illnesses, such as significant musculoskeletal injuries, antibiotic resistant infections, persistent fungal and viral infections, chemotherapy resistant cancers, and chronic pain More creative DMSO combinations (which can be produced at home) have been frequently used to successfully treat many challenging conditions (e.g., tinnitus, a wide range of eye issues, cancers, and uncomfortable scars)

In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Tim Showalter, Radiation Oncologist, Founder and Chief Medical Officer at ArteraAI. Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with Tim, covering: The attraction of radiation oncology at med school and his fascination with clinical trials His frustration with tools for cervical cancer patients led to the creation of a medical device company How his bootstrapped side project ended in an exit... but why that was inspiring and motivational to move on to the next thing The proud experience of using his own product (BrachyGel) on cancer patients in the clinic, years after coming up with the idea How ArteraAI's technology is positively disrupting the prostate cancer space, as well as its potential to scale and expand into other disease areas   Tim Showalter, MD, MPH, is a radiation oncologist and cancer researcher who serves as Chief Medical Officer at Artera, where he leads research and medical strategy. Artera is working to improve cancer care by developing AI-enabled prognostic and predictive tests. The ArteraAI Prostate Test is the first of its kind to be recommended by national clinical guidelines for routine use. Tim maintains a part-time clinical practice at the University of Virginia, remaining connected to patient care, research and education. He is the founder of Advaray and inventor of BrachyGel, a novel hydrogel-based medical device for cervical cancer radiation therapy, which is manufactured and marketed by CQ Medical. Tim serves on the board of CQ Medical and cohosts a podcast, HealthTech Remedy to explore the intricacies of innovative health technology companies. Tim is a noted speaker and advisor to start-up companies.   Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating!  Molecule to Market is also sponsored and funded by ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.

Can adenosine and a ketogenic diet help treat addiction? New research explores the powerful role of adenosine, dopamine, and metabolic health in addiction, and how dietary strategies could support recovery.In this interview, Dr. Bret Scher speaks with Dr. Susan Masino, a neuroscience and psychology professor at Trinity College, about her groundbreaking work on adenosine and its potential to regulate addiction through metabolic pathways. They dive into:The dopamine-addiction connectionThe role of adenosine in addiction and how it balances dopamine activityThe role of ketogenic diets in boosting adenosineOther mechanisms supporting keto for treating addictionWhy food, sugar, and even phone addiction may share common rootsHow metabolic therapies could support recovery from addiction, depression, and moreDr. Masino also shares insights on how habits, stress, inflammation, and neuroplasticity all intersect with metabolic health—and what that means for mental health and addiction treatment going forward.Expert Featured:Dr. Susan Masinohttps://internet3.trincoll.edu/facprofiles/default.aspx?fid=1117011Resources Mentioned:Ketogenic diet, adenosine, and dopamine in addiction and psychiatryhttps://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2025.1492306/fullFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

We've all heard that regular exercise is good for you. But a major new study published in Cell might have just found a way to bottle its benefits and deliver them to people who can't hit the gym. Over six years, the researchers tracked 13 healthy volunteers as they exercised, from a single 5km run to a 25-day running plan and they collected as much data as they could across the body including genes, proteins, metabolism, gut bacteria, and immune cells. They found that at first, exercise stresses the body out with inflammation and metabolic overload. But over time, the body adapts and rebuilds, emerging stronger and more balanced. Surprisingly they found that your kidneys play a leading role in how your body responds to exercise. Betaine is a natural molecule made by the kidneys, as a powerful 'exercise mimetic' something that can copy many of the health benefits of physical activity, especially when it comes to slowing down aging. The researchers gave betaine supplements to aging mice and found that : Their immune cells looked and acted younger. Inflammation dropped significantly. Physical coordination and memory improved. Even signs of depression faded. All without the mice needing to exercise. Betaine works by blocking a key inflammation switch in the body (called TBK1). This shuts down the chronic 'inflammaging' the slow, inflammation that drives many age-related diseases. This discovery doesn't mean you should stop moving, exercise still offers a whole package of benefits that pills can't fully replicate. But for people who are older, injured, or living with disabilities, this research could lead to real, science-backed alternatives. Betaine is already known to be safe, and the researchers believe it has strong potential as a geroprotective supplement one that could help people stay healthier, longer. Future clinical trials will tell us if these effects hold true in humans at scale. LISTEN ABOVESee omnystudio.com/listener for privacy information.

In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Gemma Budd, General Manager at Nanopharm. Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with Gemma, covering: Why being in an overlay strategic, future-focused role led her to make the tough decision to move on Identifying the joy of solving problems for customers in service-based businesses Why her holistic experience led to the GM role...and the reality in becoming the leader The factors driving growth for inhalation delivery for nasal and pulmonary routes Being a niche player in a global market - why clients don't care where you are when you know what you're doing With a background in biomedical science, Gemma has built her career over the past 15 years by leveraging and expanding that knowledge in the pharmaceutical and medical devices industry. She has worked in companies providing analytical and formulation development services, materials science consultancy and manufacturing of drug delivery systems – primarily in commercial and technical roles.  She is currently the General Manager of Nanopharm, a specialist CRO focusing on developing nasally administered and inhaled drug products for pharmaceutical companies worldwide, through her team of 75 employees in the UK. She is focused on ensuring the business continually delivers, innovates and evolves in their niche space to ensure their clients benefit from their expertise that is not widely available in the industry, developing both exceptional talent and unique technology platforms, and ensuring they combine to deliver high quality services to help get drugs to patients quickly, safely and effectively. Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating!  Molecule to Market is also sponsored and funded by ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.

●     ESS60 - Noble Prize winning Molecule ●       Inflammation and Aging  ●       ESS60 Anti Cancer Properties? ●       Controlling inflammation ●       Remove Wheat, dairy and sugary  ●       HCRP improvement with ESS60  ●       Power of olive oil  ●       And so much more!   Links mentioned in this episode! Show notes page: https://burnitnutrition.com/podcast180/ . . .  LMNT – Get a free sample pack with your first order at https://drinklmnt.com/burn . . BiOptimizers - Get Magnesium Breakthrough and 10% discount with code burnit   - http://bioptimizers.com/burnit . . Learn more about ESS60 and Chris Burres: Website: https://www.myvitalc.com/ . . Podcast Shop Page for Best Deals at https://burnitnutrition.com/shop  . Leave me a rating & review on Apple Podcasts: https://itunes.apple.com/us/podcast/burn-it-nutrition-podcast/id1195955730?mt=2  . Follow Joseph Navarro on Instagram under @BurnitNutrition . Follow Joseph Navarro on Facebook under @BurnitNutrition . Thank You for Listening!! Please share this episode! Be the one who helps spark a transformation in your family! Feedback to share? Send email to info@BurnitNutrition.com Subscribe! Don't miss another episode! Notice of Sponsorship Affiliate Disclosure with BiOptimizers, LMNT,   Fair Use Disclaimer The following podcast episode contains audio clips that are used under the doctrine of fair use as defined by United States copyright law. These clips are used for purposes of commentary, criticism, news reporting, teaching, scholarship, and research. All rights to the original audio content remain with the respective copyright holders. This use is not intended to infringe upon their rights, but to enhance the discussion and understanding of the topic at hand. Please read the full medical disclaimer  burnitnutrition.com/medical-disclaimer/

In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Jeanne Taylor Hecht, Chief Executive Officer and Chairwoman at Lexitas. Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with Jeanne, covering: How Jeanne's various roles have equipped her to become a more rounded CEO and board member. How a stint in Asia led Jeanne to develop her strategy playbook, including the importance of the client's voice. Jeanne's journey, taking on eight different boards and becoming a serial investor and advisor... and how that did not happen by accident. She said that having a strong relationship with a PE firm and missing the hands-on, day-to-day role of being a CEO led her back to the hot seat. Understanding why has being a specialist ophthalmology CRO given Lexitas traction with small to medium biotechs, and what is the future in store for CROS? Jeanne's industry career spanned over twenty-five years as a Board member and Chief Executive Officer of multiple companies, including CEO at Ora and Senior Executive at Median Technologies, IQVIA, Decision Biomarkers, and the UNC Oncology Protocol Office. Jeanne also launched and expanded a Life Sciences consulting practice that supported companies with sales, marketing, and market growth strategies and advisory and board work. She is primarily motivated by helping to bring relief to patients.  Jeanne is an active Advisory Board Member for the University of North Carolina Chapel Hill Kenan-Flagler's Business School and Lecturer at the business school. She contributed to the creation of Wake Forest University's master's in clinical research program and remains an active industry advisor to the school. She holds a Bachelor of Science from the University of Michigan and a Master of Business Administration from the university's Ross School of Business. Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating!  Molecule to Market is also sponsored and funded by ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.

Summer is here, and that means we are one season closer to a new season of college hoops! This week, Bob highlights the key matchups for the ACC/SEC challenge for both the men and the women. Later, he welcomes Kevin Blossom, SVP and GM, Retail of MOLECULE to talk about the Naismith Defensive Player of the Year, presented by Molecule, and the benefits of sports sponsorships.WANT TO SUPPORT A TROPHY LIFE?Leave a rating and review on iTunes, Spotify, or wherever you get your podcasts. Your feedback only helps make the show better, and we appreciate your support! For more information about the Naismith Trophy Award, visit our home on the web.

Efficacy And Safety of AZD0780, An Oral Small Molecule PCSK9 Inhibitor For Treatment Of Hypercholesterolemia: Results From A Ph2b Randomized Placebo-controlled Clinical Trial

Michael Long, author of Taming the Molecule of More and co-author of The Molecule of More,  joins us to discuss the science of dopamine, why we're constantly chasing "more," and how understanding brain chemistry can transform our approach to retirement and finding meaning. Michael Long joins us from the Washington, DC area. _______________________ Do you know what you're retiring to? Registration is now open for the two Fall groups - Design Your New Life in Retirement Very early bird discount available for a limited time | Register now _______________________ Bio Michael Long is a physicist, writer, and co-author of the international bestseller The Molecule of More (translated into 25 languages, 500,000+ copies sold) and the author of Taming the Molecule of More. As a playwright, more than 20 of his shows have been produced, most on New York stages. As a screenwriter, his honors include finalist for the grand prize in screenwriting at the Slamdance Film Festival. As a speechwriter, Mr. Long has written for members of Congress, U.S. cabinet secretaries, governors, diplomats, business executives, and presidential candidates. A popular speaker and educator, Mr. Long has addressed audiences around the world, including in a keynote at Oxford University. He teaches writing at Georgetown University, where he is a former director of writing. Mr. Long pursued undergraduate studies at Murray State University and graduate studies at Vanderbilt University. _______________________ For More on Michael Long Taming the Molecule of More: A Step-by-Step Guide to Make Dopamine Work for You Website: tamingthemolecule.com Books: The Molecule of More and  Contact: Available through website for book club discussions ______________________ Podcast Conversations You May Like Edit Your Life – Elisabeth Sharp McKetta The Stress Paradox – Sharon Bergquist, MD The Science of Longevity – Coleen T. Murphy _______________________ Mentioned in This Podcast Conversation The Molecule of More by Daniel Leiberman and Michael Long _______________________ About The Retirement Wisdom Podcast There are many podcasts on retirement, often hosted by financial advisors with their own financial motives, that cover the money side of the street. This podcast is different. You'll get smarter about the investment decisions you'll make about the most important asset you'll have in retirement: your time. About Retirement Wisdom I help people who are retiring, but aren't quite done yet, discover what's next and build their custom version of their next life. A meaningful retirement doesn't just happen by accident. Schedule a call today to discuss how The Designing Your Life process created by Bill Burnett & Dave Evans can help you make your life in retirement a great one – on your own terms. About Your Podcast Host Joe Casey is an executive coach who also helps people design their next life after their primary career and create their version of The Multipurpose Retirement.™ He created his own next chapter after a twenty-six-year career at Merrill Lynch, where he was Senior Vice President and Head of HR for Global Markets & Investment Banking. Today, in addition to his work with clients, Joe hosts The Retirement Wisdom Podcast, which thanks to his guests and loyal listeners, ranks in the top 1 % globally in popularity by Listen Notes, with over 1.6 million downloads. Business Insider has recognized Joe as one of 23 innovative coaches who are making a difference. He's the author of Win the Retirement Game: How to Outsmart the 9 Forces Trying to Steal Your Joy. _______________________ Wise Quotes On Dopamine as the "Molecule of More" "If you're not familiar with dopamine, you hear it's the molecule of happiness. It's the thing that makes you happy. You get that dopamine buzz. And it turns out he's a psychiatrist, of course. I'm a physicist.

Welcome back to this week's Friday Review where I can't wait to share with you the best of the week!     I'm looking forward to reviewing:     Magic Molecule (product review) Four Thousand Weeks (book review) Autoimmune Disease & Heart Failure (research) Collagen & Joint Support (research)     For all the details tune into this week's Cabral Concept 3416 – Enjoy the show and let me know what you thought!   - - - For Everything Mentioned In Today's Show: StephenCabral.com/3416 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Garren Hillow, Executive Coach and Author. Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with Garren, covering: Why not being a PhD scientist really helped him in selling science How recruiting for glory enabled him to hire the best people on the planet Buying a CRO business and getting comfortable with the risk of bankruptcy Going all in on his business, and sticking true to its core vision, enabled this David to beat the sector's Goliaths From struggling to make payroll, to the perfect storm that led to a $190m sale Garren Hilow is a biotech entrepreneur, advisor, and speaker best known for co-founding Abveris, an antibody discovery company he scaled without venture capital and ultimately sold to Twist Bioscience for $ 190 M. His journey is a masterclass in building a high-value, capital-efficient business in one of the world's toughest industries. At Abveris, Garren focused on resourcefulness, sales mastery, and building a sellable system, not just a company, allowing him to achieve a major exit while staying true to his entrepreneurial ideals. Today, Garren works with founders and CEOs across life sciences and B2B sectors, helping them build scalable, independent businesses without sacrificing control. He's passionate about empowering entrepreneurs to create long-term value through practical skills like sales, leadership, and strategic marketing, always with an eye on sustainable, founder-friendly growth. Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating!  Molecule to Market is also sponsored and funded by  ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.

This week, Bob chats with our 2025 Naismith Defensive Player of the Year, presented by MOLECULE --Creighton's Ryan Kalkbrenner! He's one of the Creighton's and Big East's all-time greats! Plus, our weekly news and notes! WANT TO SUPPORT A TROPHY LIFE?Leave a rating and review on iTunes, Spotify, or wherever you get your podcasts. Your feedback only helps make the show better, and we appreciate your support! For more information about the Naismith Trophy Award, visit our home on the web.

Alberto Vazquez-Salazar, PhD, is a NASA postdoctoral fellow working at UCLA in the lab of Professor Irene Chen. He studies how life may have started on Earth by focusing on a molecule called RNA, or ribonucleic acid, which is a critical molecule that exists in all living things. His work is a part of astrobiology that explores how life began on Earth and how we might find signs of life elsewhere in the universe. In this episode of Further Together, Vazquez-Salazar talks to host Michael Holtz about how science has always seemed to be part of his life. Growing up in Mexico City, his mom, a botanist, kept books and plant specimens everywhere. “Science was just part of everyday life,” he says. “It was as normal as finding cereal in the pantry.” Listen to learn more about Vazquez-Salazar's journey to NASA. To learn more about the NASA Postdoctoral Program and when applications open, visit https://npp.orau.org/index.html

Live Longer & Better: Biohacking Longevity with the ESS60 Miracle Molecule [Chris Burres]What if you could increase your energy, improve your sleep, sharpen your focus, and even extend your lifespan—all with one breakthrough supplement?

Thanks to our sponsor, Venice.AI. Get 20% off a pro plan using our link: venice.ai/coolstuff and code coolstuff. First direct observation of the trapped waves that shook the world in 2023 Are We Ready for Death in Space? Scientists find immune molecule that supercharges plant growth Connect with the show: coolstuffcommute@gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Angelo Gatto, CEO at Chanelle Pharma. Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with Angelo, covering: Why he chose to follow a big pharma divestment into the CDMO industry. The tricky transition from big pharma technical to commercial CDMO BD when he had the view of "I don't like sales people"! How commercial trust is developed through preparation, character and competences Why he couldn't resist the 'made for him' CEO role at Chanelle Pharma Making key strategic decisions to that make the business very attractive to a range of future buyers. The humanisation of animal care driving the pipeline and development of new products for small and large animals Angelo brings over 25 years of international experience in pharmaceuticals, in a career spanning animal health, human health and CDMO. He has held operations, commercial and management roles at Johnson & Johnson, AlfaSigma, Pfizer, Aenova Group, Adragos Pharma.  Since July 2024 is the CEO of Chanelle Pharma, Before joining Chanelle he also created a boutique advisory firm that has helped companies in last years to succeed in M&A deals and value creation, mostly in the CDMO space. Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating! Molecule to Market is also sponsored and funded by ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.  

Is methylene blue really the next “miracle” molecule for brain health, longevity, and energy — or just another case of biohacking gone rogue? In this episode of The Balanced Bodies Blueprint, Vinny and Dr. Eryn Russo break down the real science versus the hype. Methylene blue started as a textile dye in the 1800s, became the first synthetic drug to treat malaria, and is now popping up in medspa clinics and influencer wellness stacks. But here's the catch: while it's a legitimate drug used in hospitals for something like methemoglobinemia, there's little evidence it actually works for boosting mitochondria, cognitive function, or energy in healthy people. Vinny and Eryn walk you through: ✅ What methylene blue is (and what it's really approved for) ✅ The difference between mechanistic theory (cell cultures) and human evidence (spoiler: most studies in healthy humans don't exist!) ✅ Why “mitochondrial dysfunction” is not something you casually diagnose yourself with ✅ The real risks — from serotonin syndrome to neurotoxicity — that influencers never mention ✅ The role of methylene blue in Alzheimer's and neuroprotection research (yes, there's promise — but not for everyone!) ✅ Why taking methylene blue casually is like “playing biochemist with a hospital dye” If you've heard the hype about methylene blue and want to know what's real and what's just another marketing myth, this is your episode. Because in a world of wellness trends, physiology doesn't care about influencer marketing — it only cares about the evidence. Connect with Us: Coach Vinny Email: vinny@balancedbodies.io Instagram: vinnyrusso_balancedbodies Facebook: Vinny Russo Dr. Eryn Email: dr.eryn@balancedbodies.io Instagram: dr.eryn_balancedbodies Facebook: Eryn Stansfield LEGION 20% OFF CODE: Go to https://legionathletics.com/ and use code RUSSO for 20% off your 1st order!

What if one molecule could help you live 90% longer?In this powerful episode, Elanie and Kay are joined by Chris Burres, scientist, author, and co-founder of MyVitalC, to explore one of the most groundbreaking discoveries in longevity science: ESS60—a molecule derived from Nobel Prize-winning research, shown to significantly extend the lifespan of animals (up to 90%!) in peer-reviewed studies.Chris breaks down the science behind ESS60, the “longevity molecule” responsible for the longest lifespan extension result in history, and shares how this discovery could be a game-changer for human health, energy, and aging.Tune in to learn:What ESS60 is and how it works at the cellular levelHow it enhances resilience, mitochondrial health, and energy productionThe myths about aging modern science is finally debunkingHow to add life to your years, not just years to your lifePractical steps you can take today to support a long, vibrant lifeIf you've ever been curious about anti-aging breakthroughs, this is the episode that makes the science simple and the solutions actionable.

In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Christiane Bardroff, COO of Rentschler Biopharma SE. Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with Christiane, covering: The importance of "knowing what you're talking about" to build confidence Being asked to build and commission an automated €800m bioprocessing plant at Teva The draw of a family-owned CDMO business servicing 170 clients worldwide, and what she loves about this ownership model The 'power of we' is doing things together as a team for the greater good of the business The power of listening to people and empowering teams that led to producing 50% more at the same site Why Rentschler Biopharma decided to exit the CGT capabilities and double down on its biologics business Christiane oversees operations across the company's sites in Germany and the US. A results-driven executive with a strong foundation in biotechnology and chemical engineering, she brings deep expertise across biomanufacturing, automation, digitalization, and leadership. Her career includes nearly a decade at Roche, where she implemented the company's first paperless manufacturing process. At Teva Biotech, she led the development of a €800M large-scale facility and was part of the global management team, earning Teva's Mission and Values Award in 2021. Since joining Rentschler in 2022, Christiane has advanced rapidly through senior leadership roles and now leads all operational areas, including manufacturing, quality, engineering, regulatory, and supply chain. Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating! Molecule to Market is also sponsored and funded by ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.

251: Today I'm joined by Dr. Gregory Kelly, VP of Product Development at Qualia Life. We dive into NAD+—why it's crucial for energy, aging, and overall vitality—and how to know if your levels are low. We also talk about detox, fertility, B vitamins, and what sets Qualia's NAD+ apart from the rest. If you're curious about longevity or navigating the supplement world, you won't want to miss this one. I've been using their products for years and trust them more than most on the market.  Qualia | Go to qualialife.com/REALFOODOLOGY for up to 50% off your purchase and use code REALFOODOLOGY for an additional 15%.  Topics Discussed:  What is NAD+ and why is it important for energy and aging? How can I tell if my NAD+ levels are low? What makes Qualia's NAD+ supplement different from others on the market? Can NAD+ supplements support longevity and mitochondrial health? Are supplements from Amazon safe or effective? Timestamps:  00:00:00 – Introduction  00:02:14 – What is NAD+ 00:06:12 – NAD+ and mitochondrial health 00:07:59 – NAD+ for lifespan and vitality 00:13:06 – NAD+ and longevity 00:16:56 – NAD+ for detox and stress 00:20:01 – How to naturally boost NAD+ 00:22:15 – NAD+ and fertility 00:24:23 – NAD+ and whole-body health 00:26:35 – How NAD+ is made in the body 00:27:49 – What makes Qualia NAD+ different 00:31:45 – MTHFR gene and B vitamins 00:35:11 – B vitamins' role in NAD+ 00:36:11 – Why Niagen® is used 00:37:18 – Signs of low NAD+ 00:40:04 – NAD+ research and studies 00:46:15 – Caffeine and NAD+ 00:48:15 – NAD+ dosage and usage tips 00:53:21 – Balancing NAD+ safely 00:55:06 – Fake supplements on Amazon Further Listening:  Stop Aging + Enhance Focus  | Greg Kelly of Qualia  Sponsored By: Qualia | Go to qualialife.com/REALFOODOLOGY for up to 50% off your purchase and use code REALFOODOLOGY for an additional 15%.  Check Out Qualia:  Qualia | Go to qualialife.com/REALFOODOLOGY for up to 50% off your purchase and use code REALFOODOLOGY for an additional 15%.  Instagram Podcast Check Out Courtney:  LEAVE US A VOICE MESSAGE Check Out My new FREE Grocery Guide! @realfoodology www.realfoodology.com My Immune Supplement by 2x4 Air Dr Air Purifier AquaTru Water Filter EWG Tap Water Database Produced By: Drake Peterson

Mike Long, the brilliant physicist-turned-writer and co-author of "The Molecule of More," joins us for a riveting conversation on the Addicted Mind Podcast. Together, we dissect the fascinating world of dopamine and its powerful influence over our behavior and experiences. We take a closer look at how this neurotransmitter's relentless push for future rewards often clouds our present joys, impacting everyday actions from gambling to excessive use of social media. Mike's unique perspective bridges natural patterns with human habits, offering profound insights into the mind's complex workings. In our discussion, we unravel the dual nature of dopamine, painting a vivid picture of its role as both motivator and alert system. Through engaging analogies, like the excitement of Christmas morning, we explore how dopamine shapes our desires and decision-making, propelling us toward imagined futures. Yet, the episode doesn't shy away from recognizing the challenges posed by dopamine's influence, especially in the context of modern technology and its overstimulation. By diving into the science behind neurotransmitters, we underscore the importance of balance in navigating this chemical-driven landscape. In this episode, you will hear: Mike Long's exploration of dopamine's dual nature as both a motivator and an alert system The impact of dopamine on future-focused behaviors and the overshadowing of present joys Practical strategies to balance dopamine's influence and promote mindful living Discussion on GLP-1 drugs' potential in curbing cravings and treating addiction The role of technology in amplifying dopamine-driven habits and solutions for managing screen time Techniques for fostering personal growth and relationships through intentional living Follow and Review: We'd love for you to follow us if you haven't yet. Click that purple '+' in the top right corner of your Apple Podcasts app. We'd love it even more if you could drop a review or 5-star rating over on Apple Podcasts. Simply select “Ratings and Reviews” and “Write a Review” then a quick line with your favorite part of the episode. It only takes a second and it helps spread the word about the podcast. Supporting Resources: NovusMindfulLife.com Episode Credits If you like this podcast and are thinking of creating your own, consider talking to my producer, Emerald City Productions. They helped me grow and produce the podcast you are listening to right now. Find out more at https://emeraldcitypro.com Let them know we sent you. Learn more about your ad choices. Visit megaphone.fm/adchoicesSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Mike Long, the brilliant physicist-turned-writer and co-author of "The Molecule of More," joins us for a riveting conversation on the Addicted Mind Podcast. Together, we dissect the fascinating world of dopamine and its powerful influence over our behavior and experiences. We take a closer look at how this neurotransmitter's relentless push for future rewards often clouds our present joys, impacting everyday actions from gambling to excessive use of social media. Mike's unique perspective bridges natural patterns with human habits, offering profound insights into the mind's complex workings. In our discussion, we unravel the dual nature of dopamine, painting a vivid picture of its role as both motivator and alert system. Through engaging analogies, like the excitement of Christmas morning, we explore how dopamine shapes our desires and decision-making, propelling us toward imagined futures. Yet, the episode doesn't shy away from recognizing the challenges posed by dopamine's influence, especially in the context of modern technology and its overstimulation. By diving into the science behind neurotransmitters, we underscore the importance of balance in navigating this chemical-driven landscape. In this episode, you will hear: Mike Long's exploration of dopamine's dual nature as both a motivator and an alert system The impact of dopamine on future-focused behaviors and the overshadowing of present joys Practical strategies to balance dopamine's influence and promote mindful living Discussion on GLP-1 drugs' potential in curbing cravings and treating addiction The role of technology in amplifying dopamine-driven habits and solutions for managing screen time Techniques for fostering personal growth and relationships through intentional living Follow and Review: We'd love for you to follow us if you haven't yet. Click that purple '+' in the top right corner of your Apple Podcasts app. We'd love it even more if you could drop a review or 5-star rating over on Apple Podcasts. Simply select “Ratings and Reviews” and “Write a Review” then a quick line with your favorite part of the episode. It only takes a second and it helps spread the word about the podcast. Supporting Resources: NovusMindfulLife.com Episode Credits If you like this podcast and are thinking of creating your own, consider talking to my producer, Emerald City Productions. They helped me grow and produce the podcast you are listening to right now. Find out more at https://emeraldcitypro.com Let them know we sent you. Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of the Unhooked podcast, I dive deep into the science of dopamine and addiction with special guest Mike Long, co-author of 'The Molecule of More.' Mike explains how dopamine drives addictive behaviors such as porn addiction and serial dating, and stresses the importance of finding pleasure and meaning in the present moment. Our conversation also covers practical tools and steps grounded in neuroscience to help break free from the cycle of craving and dissatisfaction. Mike shares insights on the difference between pleasure and happiness, the role of dopamine in our evolutionary biology, and the necessity of creating a balanced and meaningful life. If you're struggling with addiction of any kind, this episode offers valuable perspectives and actionable advice.

In this special solo episode, it's just me, Nathalie Niddam—nutritionist, human potential and epigenetic coach—returning to my roots and diving deep into the world of peptides. Today, I'm shining a spotlight on KPV, a fascinating and often overlooked peptide with powerful anti-inflammatory, antimicrobial, and healing properties.   What We Discuss: What are peptides? Clearing up misconceptions ... 00:01:00 KPV explained: structure and origins ... 00:03:00 How KPV works (anti-inflammatory mechanisms) ... 00:05:00 Comparison to Melanotan and tanning ... 00:08:00 KPV benefits: gut, antimicrobial, healing, immune modulation ... 00:09:00 KPV for gut and skin health ... 00:14:00 Neuroprotection and research potential ... 00:18:00 Administration methods: oral, topical, injectable ... 00:19:00 Safety profile and side effects ... 00:22:00 Tracking protocols and the Peptide Pro app ... 00:24:00 Recap and concluding remarks ... 00:30:00   Our Amazing Sponsor: BiOptimizers - MassZymes is the most complete, most potent digestive enzyme with over 102% MORE PROTEASE than the nearest competitor. That's crucial because protein is the most complex macronutrient to break down. Try MassZymes at bioptimizers.com/bionat and enter the coupon code BIONAT to get 10% off your order.   More From Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group  

In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Adriana Herrera, CEO at Pierre Fabre Pharmaceuticals (USA). Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with Adriana, covering: Why Big Pharma is such a great training ground for future pharma leaders, and how a period living and working in Mexico defined her leadership style The reality of being purchased by a big pharma like Gilead, and retaining independence as the acquired company, Kite Pharma The opening of a market opportunity that led Adriana to her first CEO role, and how the role is pushing her outside of her comfort zone Why she is optimistic about the future of manufacturing and commercialising cell therapies - innovation will find a way, but it takes time How the current geopolitical environment is adding more risk and uncertainty to an industry plagued with risk... and how that may impact investments and supply chains Adriana leads the expansion of Pierre Fabre's US presence in precision oncology, cell therapy and rare diseases with an immediate focus on the commercialization of a groundbreaking allogenic cell therapy. Most recently, Adriana served as U.S. General Manager at Kite Pharma where she successfully commercialized the autologous CART-cell therapy portfolio and led the US commercial functions. Prior to that, her experience included a tenure at Eisai as Senior Vice President and commercial head for U.S. Oncology and high-impact leadership roles at Novartis Oncology including Vice President and Global Diseases Lead for Lung and Genitourinary cancers. Adriana commenced her career at Bristol Myers-Squibb. Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating! Molecule to Market is also sponsored and funded by ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.

In this episode of the Epigenetics Podcast, we talked with Ani Deshpande from Sanford Burnham Prebys about his work on epigenetic regulation and developing small molecules through high throughput screens for AML. Throughout our discussion, we delve into Dr. Despande's journey into the field of biology and science, tracing his evolution from a literature enthusiast in Mumbai to a dedicated cancer researcher. He reflects on his formative experiences during his PhD at Ludwig Maximilian University in Munich, where she developed murine models for refractory acute myeloid leukemia (AML). We examine these models' contributions to therapeutic discovery and understanding the intricate mechanisms underscoring AML's complexities. Transitioning to his postdoctoral work at Scott Armstrong's lab in Boston, Dr. Despande shares his insights on the importance of epigenetic regulators, such as DOT1L, in leukemias, and how they can serve as strategic therapeutic targets. His ambitious pursuit of translational research is further highlighted through his efforts in developing a conditional knockout mouse model and his collaborative work utilizing CRISPR technology to refine our understanding of epigenetic regulation in cancer pathogenesis. Moreover, we engage in a conversation about the challenges and opportunities that arise when establishing his lab at Sanford Burnham Prebys. Dr. Despande candidly discusses the delicate balance between pursuing topics of genuine interest versus adhering to grant fundability, underlining the tension researchers face in the current scientific landscape. His emphasis on the critical need for innovation within lab settings serves as a motivational call for emerging scientists to venture beyond the established templates that often inhibit groundbreaking discoveries. We conclude our dialogue with an exploration of his recent projects, which involve targeting specific epigenetic modifiers and how his lab's findings can contribute to greater understanding and potential treatments for not only AML but also other pediatric cancers driven by gene fusions. Dr. Despande's insights into the integration of modern technologies, such as CRISPR libraries, exemplify his commitment to pushing the boundaries of cancer research. In addition to discussing his scientific contributions, we touch upon Dr. Despande's foray into podcasting (The Discovery Dialogues), shedding light on his motivation to bridge the communication gap between scientists and the broader public. He articulates his desire to demystify scientific discoveries and promote awareness about the intricate journey of research that lays the groundwork for medical advancements. This multidimensional discussion not only highlights his scientific achievements but also emphasizes the importance of effective science communication in fostering public understanding and appreciation of research.   References Deshpande AJ, Cusan M, Rawat VP, Reuter H, Krause A, Pott C, Quintanilla-Martinez L, Kakadia P, Kuchenbauer F, Ahmed F, Delabesse E, Hahn M, Lichter P, Kneba M, Hiddemann W, Macintyre E, Mecucci C, Ludwig WD, Humphries RK, Bohlander SK, Feuring-Buske M, Buske C. Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia. Cancer Cell. 2006 Nov;10(5):363-74. doi: 10.1016/j.ccr.2006.08.023. PMID: 17097559. Deshpande AJ, Deshpande A, Sinha AU, Chen L, Chang J, Cihan A, Fazio M, Chen CW, Zhu N, Koche R, Dzhekieva L, Ibáñez G, Dias S, Banka D, Krivtsov A, Luo M, Roeder RG, Bradner JE, Bernt KM, Armstrong SA. AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes. Cancer Cell. 2014 Dec 8;26(6):896-908. doi: 10.1016/j.ccell.2014.10.009. Epub 2014 Nov 20. PMID: 25464900; PMCID: PMC4291116. Sinha S, Barbosa K, Cheng K, Leiserson MDM, Jain P, Deshpande A, Wilson DM 3rd, Ryan BM, Luo J, Ronai ZA, Lee JS, Deshpande AJ, Ruppin E. A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing. Nat Commun. 2021 Nov 11;12(1):6512. doi: 10.1038/s41467-021-26788-6. Erratum in: Nat Commun. 2022 May 16;13(1):2828. doi: 10.1038/s41467-022-30475-5. PMID: 34764240; PMCID: PMC8586238.   Related Episodes Targeting COMPASS to Cure Childhood Leukemia (Ali Shilatifard) The Menin-MLL Complex and Small Molecule Inhibitors (Yadira Soto-Feliciano) MLL Proteins in Mixed-Lineage Leukemia (Yali Dou)   Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com

Is hydrogen water just another overhyped health trend—or is it a legit biohack with real science behind it? In this episode, Dr. Ken Brown dives deep into the bubbling buzz around hydrogen-rich water, sparked by health influencer Gary Brecka's bold claims on Joe Rogan. Skeptical co-host Eric Rieger gets pulled into Ken's science rabbit hole as they explore the actual clinical studies behind hydrogen water—from improving metabolic health and exercise recovery to boosting brain function and telomere length. Along the way, they break down how hydrogen water is made, why tablets might be better than machines, and what this means for aging, inflammation, and gut health. It's science, it's skepticism, it's a couple of bros drinking nanobubbles in the name of longevity. Tune in and decide for yourself: hype or hope?

Dopamine makes it easy to get stuck in a cycle of never being truly satisfied. It promises happiness, but can never deliver. A more fulfilling life begins with training your brain to overcome the dopamine chase. It's easier than you think. • Comment on this episode! • Support the show and get transcripts, book lists, and more

There's a mental move that high performers swear by—but almost no one talks about it. In this episode, discover the hidden skill that could change the way you think, react, and win. Michael E. Long's back again. He's awesome and he knows about this stuff. His new book, Taming the Molecule of More, explores how dopamine drives our behavior and how we can manage its influence for a more fulfilling life.   THIS REVIEW SHOW IS BROUGHT TO YOU BY: Sleep Breakthrough by BIOptimizers - epic sleep supplement! Just go to BIOptimizers.com/tony and use code TONY10 for 10% off. In the UK? Use the same discount code at https://bioptimizers.co.uk/.

Join us in this episode as we sit down once again with Chris Burres to discuss the powerful benefits of ESS60. Commonly known as C60, ESS60 is a form of fullerene carbon molecule that is capable of improving longevity and overall wellness. Researchers have observed its ability to neutralize free radicals – resulting in reduced levels of oxidative stress and inflammation in the body. Other potential health benefits of ESS60 include enhanced cognitive function, improved immune system response, and increased energy levels… Chris is the founder and chief scientist at MyVitalC, a company that brings the transformative power of carbon 60 directly to consumers. He is also the host of the Uncovering the Secrets to Longevity: Live Beyond the Norms Podcast, the author of Live Longer and Better, the Co-Owner of EWR Digital, and the owner of SES Research. Hit play to learn about: What happens when you start reducing the negative impact of stressed mitochondria. How to create your own daily regimen of health-boosting supplements. A brief history of ESS60. Proven health strategies that promote mental clarity and vitality. Want to keep tabs on Chris's latest work? Follow him on Instagram @myvitalc! And to get 15% off your first order with MyVitalC, go to www.myvitalc.com/findinggenius. Episode also available on Apple Podcasts: https://apple.co/30PvU9C

Growth sounds beautiful—until you're knee-deep in failure, self-doubt, and a garden full of dead plants. Amy gets real with Debbie Millman—design legend, branding expert, and accidental gardener—to unpack the not-so-glamorous side of creativity, leadership, and learning to suck at something new. Debbie shares how screwing up (repeatedly) can actually make you better at just about everything and why success can kill your spark, how confidence actually works (spoiler: it's not magic), and what gardening taught her about patience, failure, and asking for help. Her new book Love Letter to a Garden isn't just about flowers—it's about finding hope in the mess and meaning in the mistakes. Oh, and her wife, Roxane Gay, included a killer tomato sauce recipe. If you've ever felt stuck, scared, or unsure where to begin, this is your reminder to grab a shovel and just plant something already. Get all of the show notes at ⁠⁠RadicalCandor.com/podcast⁠⁠. Episode Links: ⁠⁠Transcript⁠⁠ ⁠Debbie Millman  Debbie Millman: Creativity, Leadership And The Courage To Tend | Radical Candor Design Matters Love Letter to a Garden Connect: ⁠⁠Website⁠⁠ ⁠⁠Instagram⁠⁠ ⁠⁠TikTok⁠⁠ ⁠⁠LinkedIn⁠⁠ ⁠⁠YouTube⁠⁠ ⁠Bluesky⁠ Chapters: (00:00:00) Introduction Amy introduces guest Debbie Millman, designer, author, and host of Design Matters. (00:04:05) Starting Design Matters How Debbie started the podcast to reconnect with creative purpose. (00:07:17) From Maker to Manager The tough transition from doing creative work to leading others. (00:09:28) Communicating with Impact Why how you show up matters as much as what you say. (00:12:00) Feedback & Growth Learning to receive criticism and evolve from it. (00:16:48) Confidence Through Repetition Why confidence comes after doing — not before. (00:19:05) A Gardener's Beginning How one creative experiment led to Love Letter to a Garden. (00:24:54) Learning to Ask for Help A turning point in accepting guidance and sharing vulnerability. (00:27:51) Hope Over Shame Choosing to keep going — one molecule of hope at a time. (00:31:20) Processing Emotions The value of feeling your feelings, not rushing past them. (00:34:40) Fulfillment in the Process Why lasting joy is found in the act of creating, not accolades. (00:38:06) Control & Chaos Using design and gardening as ways to find agency. (00:41:11) Harvesting and Sharing Turning garden bounty into nourishment and love. (00:42:55) Something to Plant Debbie's parting wisdom: plant something—and let go. (00:45:54) Conclusion Learn more about your ad choices. Visit megaphone.fm/adchoices

The UK wants to block out the sun (!!!) - it's a fast-moving story and the latest on that today. Also, scientists are microdosing... peanuts! And you really can hack your dopamine. Welcome to the golden age of experimental living! What a line-up of topics today.  Today's guest: Michael E. Long, co-author of Taming the Molecule of More, the book every biohacker secretly wishes they'd written. Follow Michael E. Long on Instagram. Join 30k+ weekly biohackers who receive the latest tech + techniques + reviews + insider biohacking news by signing up for the weekly newsletter here.     THIS SHOW IS BROUGHT TO YOU BY: Sleep Breakthrough by BIOptimizers  Just go to  bioptimizers.com/zestology and use code TONY10 for 10% off. In the UK? Use the same discount code at https://bioptimizers.co.uk/.  

What if you could reverse the age of your heart...without leaving home? In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Anurag Singh, Chief Medical Officer of Timeline, to reveal groundbreaking science that targets cardiovascular aging at the cellular level. You'll discover how mitochondrial decline drives heart failure, why postmenopausal women face skyrocketing cardiac risks, and how one powerful molecule, Urolithin A, can rejuvenate your heart's energy systems. Dr. Singh shares clinical research showing how Urolithin A improves mitochondrial function, boosts endurance, and may even reverse biological aging markers in the heart. You'll also learn how simple lifestyle biohacks, combined with cellular nutrition, can protect your cardiovascular health and extend your healthspan. What You'll Learn in This Episode: • The link between mitochondrial decline and heart failure • Why women's cardiac risk skyrockets after menopause • How Urolithin A stimulates mitophagy and energy renewal • New human clinical data on reversing cardiac aging markers • Biohacking strategies to fortify your cardiovascular health • How to optimize endurance, recovery, and heart resilience THANK YOU TO OUR SPONSORS! -STEMREGEN | Head to https://www.stemregen.co/dave for 20% off your first order. -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. Resources: • Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Timeline Website – https://www.timeline.com/partners/dave-asprey • Timeline Instagram - https://www.instagram.com/timeline_longevity/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey's Website: https://daveasprey.com • Dave Asprey's Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 — Trailer • 02:11 — Supplements that help • 03:05 — Long-term benefits • 04:38 — Stacking with lifestyle • 22:19 — Heart health connection • 29:39 — Mitochondria & brain function • 33:04 — Glymphatic system & Alzheimer's • 33:53 — Bed height & brain health • 34:18 — Why mitochondria matter • 35:43 — Inflammation & dysfunction • 38:12 — Transplants & consciousness • 39:19 — Meditation's effects • 40:33 — The ultimate biohacking stack • 43:06 — Creatine for sleep & focus • 50:00 — Fertility insights • 57:23 — Skin health • 01:00:28 — Final thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of Skin Anarchy, host Ekta is joined by the legendary Dr. Nicholas Perricone to explore the science behind aging, inflammation, and the future of skincare. Known for pioneering the link between inflammation and aging, Dr. Perricone returns to the spotlight with his new book, The Beauty Molecule, which dives into the cutting-edge science of mitochondrial health and acetylcholine's role in reversing cellular damage.Listeners will hear how Dr. Perricone challenged conventional dermatology by developing the first anti-inflammatory skincare and diet regimen—decades ahead of its time. He breaks down how mitochondrial dysfunction contributes to aging and inflammation, and why boosting acetylcholine—the “beauty molecule”—can transform not only skin health, but overall longevity. From daily meditation and exercise to transdermal antioxidants and hydrogen water, Dr. Perricone outlines a practical roadmap for rewiring how we think about beauty and wellness.The episode also explores the therapeutic promise of peptides, hydrogen water as a metabolic therapy, and why the future of skincare may lie in biochemistry over cosmetic quick fixes. Backed by data and decades of research, this conversation will shift your perspective on aging from surface-level solutions to deep, cellular renewal.Whether you're a skincare aficionado, health professional, or wellness seeker, this episode offers an inspiring and scientifically grounded look at the future of beauty. Tune in to hear how Dr. Perricone is redefining aging—one molecule at a time.CHAPTERS:(0:00) – Introduction to Dr. Nicholas Perricone and His New Book(3:07) – The Rejection of New Ideas in Science and Medicine(4:53) – The Link Between Metabolism and Inflammation(7:06) – Developing the Anti-Inflammatory Diet and Its Impact(9:26) – Dr. Perricone's Transdermal Biotechnology and Its Impact(11:02) – Mitochondrial Health and Its Role in Aging(13:00) – Acetylcholine: The Beauty Molecule and Its Anti-Inflammatory Effects(20:53) – Hydrogen Water and Its Role in Reducing Inflammation(27:16) – The Promise of Peptides in Anti-Aging and Cognitive HealthTo learn more about Dr. Perricone, visit his website and social media.Shop The Beauty Molecule book!Don't forget to subscribe to Skin Anarchy on Apple Podcasts, Spotify, or your preferred platform. Reach out to us through email with any questions.Sign up for our newsletter!Shop all our episodes and products mentioned through our ShopMy Shelf! Hosted on Acast. See acast.com/privacy for more information.