Podcasts about Molecule

251: Today I'm joined by Dr. Gregory Kelly, VP of Product Development at Qualia Life. We dive into NAD+—why it's crucial for energy, aging, and overall vitality—and how to know if your levels are low. We also talk about detox, fertility, B vitamins, and what sets Qualia's NAD+ apart from the rest. If you're curious about longevity or navigating the supplement world, you won't want to miss this one. I've been using their products for years and trust them more than most on the market.  Qualia | Go to qualialife.com/REALFOODOLOGY for up to 50% off your purchase and use code REALFOODOLOGY for an additional 15%.  Topics Discussed:  What is NAD+ and why is it important for energy and aging? How can I tell if my NAD+ levels are low? What makes Qualia's NAD+ supplement different from others on the market? Can NAD+ supplements support longevity and mitochondrial health? Are supplements from Amazon safe or effective? Timestamps:  00:00:00 – Introduction  00:02:14 – What is NAD+ 00:06:12 – NAD+ and mitochondrial health 00:07:59 – NAD+ for lifespan and vitality 00:13:06 – NAD+ and longevity 00:16:56 – NAD+ for detox and stress 00:20:01 – How to naturally boost NAD+ 00:22:15 – NAD+ and fertility 00:24:23 – NAD+ and whole-body health 00:26:35 – How NAD+ is made in the body 00:27:49 – What makes Qualia NAD+ different 00:31:45 – MTHFR gene and B vitamins 00:35:11 – B vitamins' role in NAD+ 00:36:11 – Why Niagen® is used 00:37:18 – Signs of low NAD+ 00:40:04 – NAD+ research and studies 00:46:15 – Caffeine and NAD+ 00:48:15 – NAD+ dosage and usage tips 00:53:21 – Balancing NAD+ safely 00:55:06 – Fake supplements on Amazon Further Listening:  Stop Aging + Enhance Focus  | Greg Kelly of Qualia  Sponsored By: Qualia | Go to qualialife.com/REALFOODOLOGY for up to 50% off your purchase and use code REALFOODOLOGY for an additional 15%.  Check Out Qualia:  Qualia | Go to qualialife.com/REALFOODOLOGY for up to 50% off your purchase and use code REALFOODOLOGY for an additional 15%.  Instagram Podcast Check Out Courtney:  LEAVE US A VOICE MESSAGE Check Out My new FREE Grocery Guide! @realfoodology www.realfoodology.com My Immune Supplement by 2x4 Air Dr Air Purifier AquaTru Water Filter EWG Tap Water Database Produced By: Drake Peterson

Mike Long, the brilliant physicist-turned-writer and co-author of "The Molecule of More," joins us for a riveting conversation on the Addicted Mind Podcast. Together, we dissect the fascinating world of dopamine and its powerful influence over our behavior and experiences. We take a closer look at how this neurotransmitter's relentless push for future rewards often clouds our present joys, impacting everyday actions from gambling to excessive use of social media. Mike's unique perspective bridges natural patterns with human habits, offering profound insights into the mind's complex workings. In our discussion, we unravel the dual nature of dopamine, painting a vivid picture of its role as both motivator and alert system. Through engaging analogies, like the excitement of Christmas morning, we explore how dopamine shapes our desires and decision-making, propelling us toward imagined futures. Yet, the episode doesn't shy away from recognizing the challenges posed by dopamine's influence, especially in the context of modern technology and its overstimulation. By diving into the science behind neurotransmitters, we underscore the importance of balance in navigating this chemical-driven landscape. In this episode, you will hear: Mike Long's exploration of dopamine's dual nature as both a motivator and an alert system The impact of dopamine on future-focused behaviors and the overshadowing of present joys Practical strategies to balance dopamine's influence and promote mindful living Discussion on GLP-1 drugs' potential in curbing cravings and treating addiction The role of technology in amplifying dopamine-driven habits and solutions for managing screen time Techniques for fostering personal growth and relationships through intentional living Follow and Review: We'd love for you to follow us if you haven't yet. Click that purple '+' in the top right corner of your Apple Podcasts app. We'd love it even more if you could drop a review or 5-star rating over on Apple Podcasts. Simply select “Ratings and Reviews” and “Write a Review” then a quick line with your favorite part of the episode. It only takes a second and it helps spread the word about the podcast. Supporting Resources: NovusMindfulLife.com Episode Credits If you like this podcast and are thinking of creating your own, consider talking to my producer, Emerald City Productions. They helped me grow and produce the podcast you are listening to right now. Find out more at https://emeraldcitypro.com Let them know we sent you. Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of the Unhooked podcast, I dive deep into the science of dopamine and addiction with special guest Mike Long, co-author of 'The Molecule of More.' Mike explains how dopamine drives addictive behaviors such as porn addiction and serial dating, and stresses the importance of finding pleasure and meaning in the present moment. Our conversation also covers practical tools and steps grounded in neuroscience to help break free from the cycle of craving and dissatisfaction. Mike shares insights on the difference between pleasure and happiness, the role of dopamine in our evolutionary biology, and the necessity of creating a balanced and meaningful life. If you're struggling with addiction of any kind, this episode offers valuable perspectives and actionable advice.

In this special solo episode, it's just me, Nathalie Niddam—nutritionist, human potential and epigenetic coach—returning to my roots and diving deep into the world of peptides. Today, I'm shining a spotlight on KPV, a fascinating and often overlooked peptide with powerful anti-inflammatory, antimicrobial, and healing properties.   What We Discuss: What are peptides? Clearing up misconceptions ... 00:01:00 KPV explained: structure and origins ... 00:03:00 How KPV works (anti-inflammatory mechanisms) ... 00:05:00 Comparison to Melanotan and tanning ... 00:08:00 KPV benefits: gut, antimicrobial, healing, immune modulation ... 00:09:00 KPV for gut and skin health ... 00:14:00 Neuroprotection and research potential ... 00:18:00 Administration methods: oral, topical, injectable ... 00:19:00 Safety profile and side effects ... 00:22:00 Tracking protocols and the Peptide Pro app ... 00:24:00 Recap and concluding remarks ... 00:30:00   Our Amazing Sponsor: BiOptimizers - MassZymes is the most complete, most potent digestive enzyme with over 102% MORE PROTEASE than the nearest competitor. That's crucial because protein is the most complex macronutrient to break down. Try MassZymes at bioptimizers.com/bionat and enter the coupon code BIONAT to get 10% off your order.   More From Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group  

In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Adriana Herrera, CEO at Pierre Fabre Pharmaceuticals (USA). Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with Adriana, covering: Why Big Pharma is such a great training ground for future pharma leaders, and how a period living and working in Mexico defined her leadership style The reality of being purchased by a big pharma like Gilead, and retaining independence as the acquired company, Kite Pharma The opening of a market opportunity that led Adriana to her first CEO role, and how the role is pushing her outside of her comfort zone Why she is optimistic about the future of manufacturing and commercialising cell therapies - innovation will find a way, but it takes time How the current geopolitical environment is adding more risk and uncertainty to an industry plagued with risk... and how that may impact investments and supply chains Adriana leads the expansion of Pierre Fabre's US presence in precision oncology, cell therapy and rare diseases with an immediate focus on the commercialization of a groundbreaking allogenic cell therapy. Most recently, Adriana served as U.S. General Manager at Kite Pharma where she successfully commercialized the autologous CART-cell therapy portfolio and led the US commercial functions. Prior to that, her experience included a tenure at Eisai as Senior Vice President and commercial head for U.S. Oncology and high-impact leadership roles at Novartis Oncology including Vice President and Global Diseases Lead for Lung and Genitourinary cancers. Adriana commenced her career at Bristol Myers-Squibb. Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating! Molecule to Market is also sponsored and funded by ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.

In this episode of the Epigenetics Podcast, we talked with Ani Deshpande from Sanford Burnham Prebys about his work on epigenetic regulation and developing small molecules through high throughput screens for AML. Throughout our discussion, we delve into Dr. Despande's journey into the field of biology and science, tracing his evolution from a literature enthusiast in Mumbai to a dedicated cancer researcher. He reflects on his formative experiences during his PhD at Ludwig Maximilian University in Munich, where she developed murine models for refractory acute myeloid leukemia (AML). We examine these models' contributions to therapeutic discovery and understanding the intricate mechanisms underscoring AML's complexities. Transitioning to his postdoctoral work at Scott Armstrong's lab in Boston, Dr. Despande shares his insights on the importance of epigenetic regulators, such as DOT1L, in leukemias, and how they can serve as strategic therapeutic targets. His ambitious pursuit of translational research is further highlighted through his efforts in developing a conditional knockout mouse model and his collaborative work utilizing CRISPR technology to refine our understanding of epigenetic regulation in cancer pathogenesis. Moreover, we engage in a conversation about the challenges and opportunities that arise when establishing his lab at Sanford Burnham Prebys. Dr. Despande candidly discusses the delicate balance between pursuing topics of genuine interest versus adhering to grant fundability, underlining the tension researchers face in the current scientific landscape. His emphasis on the critical need for innovation within lab settings serves as a motivational call for emerging scientists to venture beyond the established templates that often inhibit groundbreaking discoveries. We conclude our dialogue with an exploration of his recent projects, which involve targeting specific epigenetic modifiers and how his lab's findings can contribute to greater understanding and potential treatments for not only AML but also other pediatric cancers driven by gene fusions. Dr. Despande's insights into the integration of modern technologies, such as CRISPR libraries, exemplify his commitment to pushing the boundaries of cancer research. In addition to discussing his scientific contributions, we touch upon Dr. Despande's foray into podcasting (The Discovery Dialogues), shedding light on his motivation to bridge the communication gap between scientists and the broader public. He articulates his desire to demystify scientific discoveries and promote awareness about the intricate journey of research that lays the groundwork for medical advancements. This multidimensional discussion not only highlights his scientific achievements but also emphasizes the importance of effective science communication in fostering public understanding and appreciation of research.   References Deshpande AJ, Cusan M, Rawat VP, Reuter H, Krause A, Pott C, Quintanilla-Martinez L, Kakadia P, Kuchenbauer F, Ahmed F, Delabesse E, Hahn M, Lichter P, Kneba M, Hiddemann W, Macintyre E, Mecucci C, Ludwig WD, Humphries RK, Bohlander SK, Feuring-Buske M, Buske C. Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia. Cancer Cell. 2006 Nov;10(5):363-74. doi: 10.1016/j.ccr.2006.08.023. PMID: 17097559. Deshpande AJ, Deshpande A, Sinha AU, Chen L, Chang J, Cihan A, Fazio M, Chen CW, Zhu N, Koche R, Dzhekieva L, Ibáñez G, Dias S, Banka D, Krivtsov A, Luo M, Roeder RG, Bradner JE, Bernt KM, Armstrong SA. AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes. Cancer Cell. 2014 Dec 8;26(6):896-908. doi: 10.1016/j.ccell.2014.10.009. Epub 2014 Nov 20. PMID: 25464900; PMCID: PMC4291116. Sinha S, Barbosa K, Cheng K, Leiserson MDM, Jain P, Deshpande A, Wilson DM 3rd, Ryan BM, Luo J, Ronai ZA, Lee JS, Deshpande AJ, Ruppin E. A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing. Nat Commun. 2021 Nov 11;12(1):6512. doi: 10.1038/s41467-021-26788-6. Erratum in: Nat Commun. 2022 May 16;13(1):2828. doi: 10.1038/s41467-022-30475-5. PMID: 34764240; PMCID: PMC8586238.   Related Episodes Targeting COMPASS to Cure Childhood Leukemia (Ali Shilatifard) The Menin-MLL Complex and Small Molecule Inhibitors (Yadira Soto-Feliciano) MLL Proteins in Mixed-Lineage Leukemia (Yali Dou)   Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com

Is hydrogen water just another overhyped health trend—or is it a legit biohack with real science behind it? In this episode, Dr. Ken Brown dives deep into the bubbling buzz around hydrogen-rich water, sparked by health influencer Gary Brecka's bold claims on Joe Rogan. Skeptical co-host Eric Rieger gets pulled into Ken's science rabbit hole as they explore the actual clinical studies behind hydrogen water—from improving metabolic health and exercise recovery to boosting brain function and telomere length. Along the way, they break down how hydrogen water is made, why tablets might be better than machines, and what this means for aging, inflammation, and gut health. It's science, it's skepticism, it's a couple of bros drinking nanobubbles in the name of longevity. Tune in and decide for yourself: hype or hope?

In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Victor Diaz, Co-Founder of Solitek. Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with Victor, covering: Falling in love with medicinal chemistry and ending up experiencing the culture shock of North East England! Why Victor fell in love with working on a variety of projects at CROs/CDMOs The benefits of solid state chemistry and its value in pre-clinical formulation development The starting story of Solitek and the decision not to take the easier path to becoming consultants His views on the market outlook and how the application of AI will impact the development pathway Victor obtained his Ph.D. in Organic Chemistry from the University of Seville in 1998 before moving to the UK, where he built most of his professional career. Originally trained as a synthetic and medicinal chemist, he began his career at High Force Research and Medivir. He later transitioned from drug discovery to early development, marking the start of his journey in solid-state science at Pharmorphix. There, he progressed to Projects Director and later Site Manager, playing a key role in the company's acquisition by Johnson Matthey from Sigma-Aldrich. Victor then spent five years as Head of Physical Sciences at Almac, leading one of the largest solid-state teams in Europe and providing pharmaceutical companies with expert support in crystallisation, polymorphism, and material characterisation. After more than 20 years in the UK, Victor returned to Spain to co-found Solitek, continuing his mission to deliver solid-state and preclinical development services to the pharmaceutical and biotech industries. He currently serves as Operations Director, driving the company's growth and innovation in the field. Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating! Molecule to Market is also sponsored and funded by ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.  

Chris Burres is a scientist, entrepreneur, and co-founder of MyVitalC, best known for bringing ESS60—a purified form of Carbon 60—to the health and wellness world. In this episode, Chris shares how this NASA-researched and Nobel Prize-winning longevity molecule is making waves in the worlds of biohacking, recovery, and cellular health.We dive into the science behind ESS60, how it supports your cells in managing oxidative stress, and what it means for energy, sleep, inflammation, and healthy aging. Chris also opens up about his surprising path to entrepreneurship, the value gleaned from improv comedy, and why optimizing your health is as much about consistency as innovation.This episode is a must-listen if you're interested in cutting-edge wellness, performance, and the truth about supplements.What You'll Learn in This Episode:What ESS60 is and how it differs from regular C60Why NASA and scientists were originally interested in this moleculeHow it works at the mitochondrial level to buffer oxidative stressReal-world benefits users report, from sleep to energy to inflammation supportChris's entrepreneurial journey and improv backgroundThe critical importance of protein as you age— Episode Chapter Big Ideas (timing may not be exact) —00:00 – Introduction00:53 – How Chris Burres got into improv and what it taught him about life & communication07:08 – What is ESS60 and how did Chris discover it?14:00 – The difference between C60 and ESS60 (and the supplement industry's quality problem)20:36 – Antioxidant mechanism explained: The BOSS Theory28:24 – Can ESS60 help with inflammation and oxidative stress?34:45 – The FDA, claims, and why language matters in supplements37:49 – Alcohol, hangovers, and “party recovery”39:27 – What it was like writing a book with a 2x NYT #1 bestselling author43:16 – Chris's current biohacking experiments: peptides, HCL, MOTC49:20 – Ultra-endurance athletes using MyVitalC to recover55:02 – Chris's views on diet, protein, and aging58:42 – Longevity, muscle retention, and avoiding the “standard American diet”1:02:57 – What success really means to Chris1:10:25 – Where to find Chris Burres and his special offer— Key Quotes from Chris Burres — "Success is boring. It's doing the same small things over and over until they add up to something great.”"I never thought a molecule used in batteries and tires would end up helping people sleep better and live longer.”"Your only job in improv—and in life—is to make the other person look brilliant."— Connect With Chris Burres —Website (and Get $15 off): https://www.myvitalc.com/ehl/Live Longer and Better book: https://www.amazon.com/Live-Longer-Better-Journey-Achievable/dp/B0CFCPVVH3Live Longer and Better (signed book copy & part of proceeds go to Operation Underground Railroad): http://www.livelongerandbetterbook.com/ Podcast (Live Beyond The Norms): http://www.livebeyondthenorms.com/ Instagram: http://instagram.com/myvitalc YouTube: https://www.youtube.com/@MyVitalC/videos — Connect with Julian and Executive Health —LinkedIn — https://www.linkedin.com/in/julianhayesii/Ready to take your health, leadership, and performance to the next level? Book a complimentary private executive health diagnostic call with Julian Hayes II. Link below. https://calendly.com/julian-exechealth/chemistryWebsite — https://www.executivehealth.io/***DISCLAIMER: The information shared is not meant to treat or diagnose any condition. This is for educational, informational, and entertainment purposes. The content here is not intended to replace your relationship with your doctor and/or medical practitioner.

There's a mental move that high performers swear by—but almost no one talks about it. In this episode, discover the hidden skill that could change the way you think, react, and win. Michael E. Long's back again. He's awesome and he knows about this stuff. His new book, Taming the Molecule of More, explores how dopamine drives our behavior and how we can manage its influence for a more fulfilling life.   THIS REVIEW SHOW IS BROUGHT TO YOU BY: Sleep Breakthrough by BIOptimizers - epic sleep supplement! Just go to BIOptimizers.com/tony and use code TONY10 for 10% off. In the UK? Use the same discount code at https://bioptimizers.co.uk/.

Join us in this episode as we sit down once again with Chris Burres to discuss the powerful benefits of ESS60. Commonly known as C60, ESS60 is a form of fullerene carbon molecule that is capable of improving longevity and overall wellness. Researchers have observed its ability to neutralize free radicals – resulting in reduced levels of oxidative stress and inflammation in the body. Other potential health benefits of ESS60 include enhanced cognitive function, improved immune system response, and increased energy levels… Chris is the founder and chief scientist at MyVitalC, a company that brings the transformative power of carbon 60 directly to consumers. He is also the host of the Uncovering the Secrets to Longevity: Live Beyond the Norms Podcast, the author of Live Longer and Better, the Co-Owner of EWR Digital, and the owner of SES Research. Hit play to learn about: What happens when you start reducing the negative impact of stressed mitochondria. How to create your own daily regimen of health-boosting supplements. A brief history of ESS60. Proven health strategies that promote mental clarity and vitality. Want to keep tabs on Chris's latest work? Follow him on Instagram @myvitalc! And to get 15% off your first order with MyVitalC, go to www.myvitalc.com/findinggenius. Episode also available on Apple Podcasts: https://apple.co/30PvU9C

Growth sounds beautiful—until you're knee-deep in failure, self-doubt, and a garden full of dead plants. Amy gets real with Debbie Millman—design legend, branding expert, and accidental gardener—to unpack the not-so-glamorous side of creativity, leadership, and learning to suck at something new. Debbie shares how screwing up (repeatedly) can actually make you better at just about everything and why success can kill your spark, how confidence actually works (spoiler: it's not magic), and what gardening taught her about patience, failure, and asking for help. Her new book Love Letter to a Garden isn't just about flowers—it's about finding hope in the mess and meaning in the mistakes. Oh, and her wife, Roxane Gay, included a killer tomato sauce recipe. If you've ever felt stuck, scared, or unsure where to begin, this is your reminder to grab a shovel and just plant something already. Get all of the show notes at ⁠⁠RadicalCandor.com/podcast⁠⁠. Episode Links: ⁠⁠Transcript⁠⁠ ⁠Debbie Millman  Debbie Millman: Creativity, Leadership And The Courage To Tend | Radical Candor Design Matters Love Letter to a Garden Connect: ⁠⁠Website⁠⁠ ⁠⁠Instagram⁠⁠ ⁠⁠TikTok⁠⁠ ⁠⁠LinkedIn⁠⁠ ⁠⁠YouTube⁠⁠ ⁠Bluesky⁠ Chapters: (00:00:00) Introduction Amy introduces guest Debbie Millman, designer, author, and host of Design Matters. (00:04:05) Starting Design Matters How Debbie started the podcast to reconnect with creative purpose. (00:07:17) From Maker to Manager The tough transition from doing creative work to leading others. (00:09:28) Communicating with Impact Why how you show up matters as much as what you say. (00:12:00) Feedback & Growth Learning to receive criticism and evolve from it. (00:16:48) Confidence Through Repetition Why confidence comes after doing — not before. (00:19:05) A Gardener's Beginning How one creative experiment led to Love Letter to a Garden. (00:24:54) Learning to Ask for Help A turning point in accepting guidance and sharing vulnerability. (00:27:51) Hope Over Shame Choosing to keep going — one molecule of hope at a time. (00:31:20) Processing Emotions The value of feeling your feelings, not rushing past them. (00:34:40) Fulfillment in the Process Why lasting joy is found in the act of creating, not accolades. (00:38:06) Control & Chaos Using design and gardening as ways to find agency. (00:41:11) Harvesting and Sharing Turning garden bounty into nourishment and love. (00:42:55) Something to Plant Debbie's parting wisdom: plant something—and let go. (00:45:54) Conclusion Learn more about your ad choices. Visit megaphone.fm/adchoices

The UK wants to block out the sun (!!!) - it's a fast-moving story and the latest on that today. Also, scientists are microdosing... peanuts! And you really can hack your dopamine. Welcome to the golden age of experimental living! What a line-up of topics today.  Today's guest: Michael E. Long, co-author of Taming the Molecule of More, the book every biohacker secretly wishes they'd written. Follow Michael E. Long on Instagram. Join 30k+ weekly biohackers who receive the latest tech + techniques + reviews + insider biohacking news by signing up for the weekly newsletter here.     THIS SHOW IS BROUGHT TO YOU BY: Sleep Breakthrough by BIOptimizers  Just go to  bioptimizers.com/zestology and use code TONY10 for 10% off. In the UK? Use the same discount code at https://bioptimizers.co.uk/.  

In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Jeremie Trochu, CEO at Ardena. Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with Jeremie, covering: The value of hitting the road and getting in front of clients, helping build several career-critical skills The big decision to leave med-tech giant GE and move to an ambitious, growing CDMO called...Catalent How the stars aligned to move back to Europe and join Ardena as CEO...and the secret sauce behind its suite of integrated development capabilities A transformational acquisition of Catalent's Somerset, NJ facility to help take Ardena to the next level as a global CDMO The importance of remembering that we are part of a cyclical industry and must ride out the lows, but we must remain adaptive and bullish about the market's growth Why VUCA (volatility, uncertainty, complexity, ambiguity) is inevitable Jeremie joined Ardena as Chief Executive Officer in June 2024. He brings an extensive knowledge of the life sciences and CDMO industry and a proven track record of success in the biopharma sector. He has 20 years of experience building and growing businesses globally, expanding into new markets, and leading large-scale transformations in publicly traded and privately held companies.  Jeremie was previously part of the team that helped transform Catalent from a private equity spinoff into a publicly traded global CDMO. During his tenure there, he led multiple companies' successful acquisitions and integrations. He holds a master's degree in Business Administration from EMLyon, France. Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating! Molecule to Market is also sponsored and funded by ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.

Addictive behaviors are becoming endemic in modern society, driven by excessive activation of the brain's dopamine system. Is it possible to tame our neurobiology? On this episode, Michael Long discussed his book, Taming the Molecule of More.

What if you could reverse the age of your heart...without leaving home? In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Anurag Singh, Chief Medical Officer of Timeline, to reveal groundbreaking science that targets cardiovascular aging at the cellular level. You'll discover how mitochondrial decline drives heart failure, why postmenopausal women face skyrocketing cardiac risks, and how one powerful molecule, Urolithin A, can rejuvenate your heart's energy systems. Dr. Singh shares clinical research showing how Urolithin A improves mitochondrial function, boosts endurance, and may even reverse biological aging markers in the heart. You'll also learn how simple lifestyle biohacks, combined with cellular nutrition, can protect your cardiovascular health and extend your healthspan. What You'll Learn in This Episode: • The link between mitochondrial decline and heart failure • Why women's cardiac risk skyrockets after menopause • How Urolithin A stimulates mitophagy and energy renewal • New human clinical data on reversing cardiac aging markers • Biohacking strategies to fortify your cardiovascular health • How to optimize endurance, recovery, and heart resilience THANK YOU TO OUR SPONSORS! -STEMREGEN | Head to https://www.stemregen.co/dave for 20% off your first order. -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. Resources: • Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Timeline Website – https://www.timeline.com/partners/dave-asprey • Timeline Instagram - https://www.instagram.com/timeline_longevity/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey's Website: https://daveasprey.com • Dave Asprey's Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 — Trailer • 02:11 — Supplements that help • 03:05 — Long-term benefits • 04:38 — Stacking with lifestyle • 22:19 — Heart health connection • 29:39 — Mitochondria & brain function • 33:04 — Glymphatic system & Alzheimer's • 33:53 — Bed height & brain health • 34:18 — Why mitochondria matter • 35:43 — Inflammation & dysfunction • 38:12 — Transplants & consciousness • 39:19 — Meditation's effects • 40:33 — The ultimate biohacking stack • 43:06 — Creatine for sleep & focus • 50:00 — Fertility insights • 57:23 — Skin health • 01:00:28 — Final thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today's Song of the Day is “Intergalactic Dance” from Ora the Molecule's album Dance Therapy, out now.

Today we're heading across the Atlantic to speak to Dr. James Field, CEO of London-based LabGenius Therapeutics.LabGenius has a really exciting mission. James and his team of 60 scientists and engineers believe in the powerful combination of human and artificial intelligence, and are pioneering an ML-driven protein engineering platform - EVA - that can design and execute experiments for the development of next-gen antibodies, including complex multispecifics.LabGenius has already raised over $75m in venture capital and built R&D deals with some major pharma and biotech players. After founding the company in 2012, James was named in Forbes' ‘30 Under 30' list for science and healthcare, and even won Innovator of the Year award from the UK's Biotech & Biological Sciences Research Council. Qualio website:https://www.qualio.com/ Previous episodes:https://www.qualio.com/from-lab-to-launch-podcast Apply to be on the show:https://forms.gle/uUH2YtCFxJHrVGeL8 Music by keldez

Not green peas! It is naturally synthesized in the body and can be found in some foods... Listen to find out what it is! And don't miss the following topics that Terry will also discuss on this show: Herb of the Day: Rosemary A Closer Look at: Triglycerides Two Studies on Multiple Sclerosis Why Bone Density Matters Effects of Ultraprocessed Foods on Your Brain

In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Rob Wood, pharma portfolio investor and Founder. Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with Rob, covering: Identifying a niche in the pharma services space that led to working with top 50 Big Pharma Growing STEM into an international powerhouse before eventually selling to UDG Healthcare Life as a pharma portfolio advisor and investor of seven pharma services companies Creating an academy that will introduce entrepreneurship to hundreds of thousands of kids How AI will impact the commercialization of new and existing drugs Rob Wood is an experienced entrepreneur in the pharma services industry. He founded, scaled, and sold STEM for €120 million, expanding into 51 countries and working with all of the top 50 pharmaceutical companies. STEM grew to over 1,000 staff globally and received the Queen's Award for International Trade. After selling STEM, Rob joined UDG plc as CEO & President of Advisory and Head of Group Business Development, leading multiple healthcare consultancies and re-modelling business development across 28 companies. Today, Rob serves as Chairman or Non-Executive Director for several healthcare service companies, focusing on growth, leadership, and investment opportunities. He holds an MBA from Newcastle University. He recently founded the Rob Wood Enterprising Futures Academy in conjunction with Newcastle University. Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating! Molecule to Market is also sponsored and funded by ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.

We meet artist Chris Levine, a British contemporary artist renowned for his pioneering work with light and lasers. His innovative approach transcends traditional mediums, integrating technology and spirituality to create immersive art installations that challenge and expand human perception. Levine's multidisciplinary practice encompasses installation, photography, performance, fashion, music, and design. He employs lasers and sound frequencies to craft environments that engage viewers on both sensory and contemplative levels. This synthesis of technology and art positions Levine's work within a broader historical context, aligning with movements that seek to transcend the physical and delve into the metaphysical.A seminal piece in Levine's portfolio is "Lightness of Being" (2004), a holographic portrait of Queen Elizabeth II. This work has been lauded for its spiritual depth and technical mastery, with the National Portrait Gallery describing it as "the most evocative image of a royal by any artist." The portrait captures the ethereal quality of light and presence, reflecting Levine's ability to merge artistic expression with technological innovation. Beyond portraiture, Levine has engaged in numerous projects that bridge various artistic disciplines. In 2012, the artist partnered with Anohni and the Johnsons for their "Swanlight" performance at Radio City Music Hall, commissioned by the MoMA, New York, integrating laser with musical performance and creating a multisensory experience. Levine's site-specific large scale installations have pushed the boundaries of light art, taking diverse settings from the historic Durham Cathedral to the contemporary landscape of Hobart, Tasmania. Aligned with the traditions of public art inspiring communities, Levine's works make immersive art accessible to broader audiences. In 2021, Levine's exhibition at Houghton Hall, 528 Hz Love Frequency, featured "Molecule of Light," a monumental 25-meter-high sculpture that transformed the landscape and cemented his innovative approach to light art. This installation not only showcased the artist's technical prowess but also his ability to harmonize art with architectural space, creating a dialogue between the artwork and its environment. Through his multidisciplinary practice, Levine continues to explore the infinite possibilities of light in art, contributing to the ongoing dialogue on the intersection of technology, spirituality, and visual expression. His work stands as a testament to the transformative power of art, inviting viewers to experience the world through a lens of heightened awareness.Follow @ChrisLevine on InstagramVisit: https://chrislevine.com/ Hosted on Acast. See acast.com/privacy for more information.

This week, we conclude our review of our Naismith Trophy awards program from San Antonio! Our MC Fran Fraschilla announces our 2025 Werner Ladder Naismith Men's Coach of the Year and our 2025 Naismith Men's Defensive Player of the Year Presented by MOLECULE.WANT TO SUPPORT A TROPHY LIFE?Leave a rating and review on iTunes, Spotify, or wherever you get your podcasts. Your feedback only helps make the show better, and we appreciate your support! For more information about the Naismith Trophy Award, visit our home on the web.

Episode # 263: This week on Balance Your Life podcast I am joined by Chris Burres. Chris is the founder and chief scientist at MyVitalC, where he manufactured a Nobel Prize-winning molecule responsible for the single longest longevity experimental result in history–a full 90% extension of life. He is also a published author, host of the Uncovering the Secrets to Longevity Health Summit, a podcast host, patent holder and master of comedy improv. He is the intersection where science meets laughter and his life's mission is to help people live longer, healthier, happier, pain-free lives with science.   On this episode we talk about MyVitalC; what it is andhow it can help us live a longer and healthier life. We talk about how he even discovered a Nobel prize winning molecule, potential side effects of consuming this molecule, how we can take it to support living longer, and so much more! Use code balancebymeghan at checkout to receive $15 offyour order of MyVitalC Spread the love by sharing this podcast with your friends and family! Don't forget to subscribe to the channel so you never miss an episode, and I would love if you took a moment to rate and review the show!Support the show by making a donation to Balance by Meghan and Balance Your Life Podcast. Show Supporthere. -------------------------------------Connect with Meghan: Instagram | TikTok | YouTube | WebsiteTo Email the Show: info@balancebymeghan.comConnect with Chris:  Instagram | TikTok | Website ------------------------------------------Join me by practicing yoga and fitness in the comfort of your home! Click here for my YouTube channel.------------------------------------------                               Access the Yoga Mama Journey: Journey to a Happy and Healthy Pregnancy and Baby Program and Guide here.--------------------------------------------Shop My Favourites: Where I share and link my favourite products, brands, skincare, beauty and wellness products (with discount codes!)------------------------------------------Use code BALANCEBYMEGHAN15 at checkout using thislink to receive 15% off your order at the Detox Market Cananda.  -------------------------------------------------Download my FREE 12 Holistic Heath Tips & Biohacks to Becoming the Healthiest Version of Yourself. This guide will help you to get fit, sleep better, uplevel your nutrition, & optimize your health. Download the guide here

In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Jon Alberdi, CEO at VIVEbiotech. Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with Jon, covering: Falling in love with the world of management and its role in influencing people and society Why, after 12 years in the B2B automotive sector, did he decide to jump into the life science space? His first impressions of the sector and the viral vector space, and why he saw nothing but potential to industrialize The before and after of a PE deal with Ampersand - speed, challenge, and intensity Riding the growth of CAR-T products, and which therapy areas are driving demand Graduating in Economics from the University of the Basque Country - Sarriko, Bilbao, he received complementary education in management and leadership. His professional career is closely tied to the Financial Function of several companies operating in diverse sectors, including investment banking, sports service management, and the automotive and aftermarket industries. In 2008, he joined the global industrial public company GKN, where he held several financial controlling roles, including the R&D department at the worldwide product development centre. He later moved to Germany to take on the responsibility of Financial Direction for a global business unit of GKN, where he stayed for five years until he joined VIVEbiotech, gaining a solid background in management within an international environment. Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating! Molecule to Market is also sponsored and funded by ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.  

On the latest episode of In Your Head Radio, I sat down with Mike Long, co-author of the international bestseller The Molecule of More and sole author of the powerful sequel Taming the Molecule of More. We dove into the science and psychology of dopamine—that feel-good neurotransmitter tied to the brain's reward circuit and pleasure center. But as Mike explains, dopamine isn't just about experiencing pleasure—it's also about chasing it. There are two ways we encounter dopamine: The pleasure of the moment and the anticipation of what might happen. When it comes to decision-making, this dual nature can cloud our judgment. Are we making choices based on present satisfaction—or are we hooked on future possibilities that may never come? Mike also raised a powerful point: when we're always chasing dopamine, we risk overlooking meaning and purpose in our lives. This conversation is a must-listen for anyone curious about how brain chemistry shapes motivation, behavior, and fulfillment. This episode and more are available on Audible, Amazon Music, Amazon Podcasts, Spotify, iHeartRadio, Apple Podcasts, iTunes, Stitcher, Player FM, and Podcast Addict.

Can one molecule preserve muscle, protect kidneys, and supercharge metabolism? In this episode of Healthy Choices, Dr. Jim LaValle joins Ray Solano to dive into OSO1—a next-gen therapeutic with wide-ranging benefits. From boosting AMPK to supporting mitochondria, OSO1 shows promise for everything from athletic recovery to age-related decline. Whether you're dealing with muscle loss or chasing peak performance, this episode is a game-changer. ---- In this episode of Healthy Choices, I sit down with Dr. Jim LaValle to talk about a breakthrough small molecule compound called OSO1. This isn't your typical supplement—it's a targeted therapeutic that supports your body's natural repair systems without relying on stimulants. We dive into how OSO1 helps preserve lean muscle, improve mitochondrial function, support glucose transport, and reduce inflammation—especially important for those on GLP-1 medications or dealing with age-related muscle loss. Dr. LaValle even shares how he uses OSO1 personally and why he sees it as a smarter, safer alternative to drugs like rapamycin. ---- Jim LaValle is a leading integrative and metabolic health expert with over 35 years of experience. He's treated thousands of patients—from elite athletes to those with chronic conditions—through his Metabolic Model for Health and founded the Metabolic Code platform to personalize care using lab data and lifestyle insights. He's been a consultant for top health brands, directed programs for the NFL Hall of Fame, and educated military special forces. A clinical instructor at George Washington University and award-winning educator, LaValle has authored 20+ books, made 1,000+ media appearances, and is recognized as one of the “50 Most Influential Pharmacists. ---- Website: https://www.jimlavalle.com Linkedin: https://www.linkedin.com/in/james-lavalle-1a6b8858/ Instagram: https://www.instagram.com/therealjimlavalle/?hl=en Facebook: https://www.facebook.com/p/Jim-LaValle-100062990514032/ ---- https://www.linkedin.com/in/ray-solano-76960463 https://www.instagram.com/pdlabs/ https://open.spotify.com/show/78tLVSbC28VnDbpw2SqiEg https://podcasts.apple.com/us/podcast/healthy-choices/id1203354304 https://www.iheart.com/podcast/256-healthy-choices-31040306/ ---- PODCAST Thank you for listening. Please subscribe and share. This podcast is produced by DrTalks.com drtalks.com/podcast-service/

In this episode, I'm diving deep with my friend and health innovator Jessica McNaughton, CEO and co-founder of C60 Power, to crack open the magic of carbon 60—a Nobel Prize-winning molecule you've probably never heard enough about. We're talking about cellular health at its core: how C60 crushes oxidative stress, eliminates free radicals (the culprits behind aging, inflammation, and maybe even cancer!), and acts as a super powered antioxidant that works in perfect harmony with your supplements and hormone therapy. If you've been spinning your wheels with fatigue, hair loss, brain fog, or stubborn weight, trust me—you'll want to hear how this molecule might just become your new not-so-secret weapon. Jessica doesn't just give you the science; she gets practical about how C60 can help balance hormones, support thyroid health, boost mood, energy, and even reduce those pesky histamine and allergy symptoms that can spike in perimenopause and menopause. Plus, you'll hear real stories—from longer, glossier hair to pain-free PMS to game-changing energy shifts in both humans and pets (yes, my dog is a fan too). If you're serious about upping your health span, slashing inflammation, and becoming that unstoppable badass I know you are, listen now. Research on C60: whatisc60.org shopc60.com/research Shop C60 products: shopc60.com Use code: DRAMIE for 10% off WHAT DO MY LABS MEAN?! Try the ultimate tool to Decode Your Labs: Understand your thyroid, hormones, and blood sugar numbers to transform your health https://dramie.com/labs/ We prescribe to all 50 states!  When you're ready to FINALLY get the help you deserve… Book a free application call: https://dramie.com/book-a-call/ Shop ALL of Dr. Amie's Fixxr® Supplements: https://betterlifedoctor.com/ EARN CE Credits: "Nurses, hold-on  – here comes the exciting part: you can earn nursing CE credits by listening to our podcasts! That's right—RNegade has teamed up with podcast hosts like me who are delivering amazing content that doesn't limit you to “thinking outside-the box,” it challenges you to BLOW-UP the box by learning from innovators, pioneers, and RENEGADES in the field of health and medicine WHILE EARNING YOUR CEs!” https://rnegade.thinkific.com/?ref=4d98d0 RATE, REVIEW AND FOLLOW ON APPLE PODCASTS If you made it this far I'm impressed! That means you really love the show and I love you for that!  So I'm going to ask you for a favor. Would you please leave a quick review or even 5⭐️. I DO read them and can't tell you how much I appreciate it! Thank you in advance!❤️  Just click here it's quick and easy : https://podcasts.apple.com/us/podcast/the-thyroid-fixer/id1529800263,  Ok ONE MORE favor…would you please subscribe and follow the show? This is a win-win! It tells the podcast powers that be that you like The Thyroid Fixer Podcast AND it lets you catch all the new episodes that come out every week. Follow with this link: https://podcasts.apple.com/us/podcast/the-thyroid-fixer/id1529800263 and never miss out on a moment of the journey! CONNECT WITH ME ON SOCIAL MEDIA: Want to get your labs reviewed and your questions answered LIVE by me? Join my exclusive Facebook group, Just Fix Your Thyroid – a supportive and empowering community designed to give you the tools, guidance, and HOPE you need on your thyroid and hormone journey.

In this episode of Skin Anarchy, host Ekta is joined by the legendary Dr. Nicholas Perricone to explore the science behind aging, inflammation, and the future of skincare. Known for pioneering the link between inflammation and aging, Dr. Perricone returns to the spotlight with his new book, The Beauty Molecule, which dives into the cutting-edge science of mitochondrial health and acetylcholine's role in reversing cellular damage.Listeners will hear how Dr. Perricone challenged conventional dermatology by developing the first anti-inflammatory skincare and diet regimen—decades ahead of its time. He breaks down how mitochondrial dysfunction contributes to aging and inflammation, and why boosting acetylcholine—the “beauty molecule”—can transform not only skin health, but overall longevity. From daily meditation and exercise to transdermal antioxidants and hydrogen water, Dr. Perricone outlines a practical roadmap for rewiring how we think about beauty and wellness.The episode also explores the therapeutic promise of peptides, hydrogen water as a metabolic therapy, and why the future of skincare may lie in biochemistry over cosmetic quick fixes. Backed by data and decades of research, this conversation will shift your perspective on aging from surface-level solutions to deep, cellular renewal.Whether you're a skincare aficionado, health professional, or wellness seeker, this episode offers an inspiring and scientifically grounded look at the future of beauty. Tune in to hear how Dr. Perricone is redefining aging—one molecule at a time.CHAPTERS:(0:00) – Introduction to Dr. Nicholas Perricone and His New Book(3:07) – The Rejection of New Ideas in Science and Medicine(4:53) – The Link Between Metabolism and Inflammation(7:06) – Developing the Anti-Inflammatory Diet and Its Impact(9:26) – Dr. Perricone's Transdermal Biotechnology and Its Impact(11:02) – Mitochondrial Health and Its Role in Aging(13:00) – Acetylcholine: The Beauty Molecule and Its Anti-Inflammatory Effects(20:53) – Hydrogen Water and Its Role in Reducing Inflammation(27:16) – The Promise of Peptides in Anti-Aging and Cognitive HealthTo learn more about Dr. Perricone, visit his website and social media.Shop The Beauty Molecule book!Don't forget to subscribe to Skin Anarchy on Apple Podcasts, Spotify, or your preferred platform. Reach out to us through email with any questions.Sign up for our newsletter!Shop all our episodes and products mentioned through our ShopMy Shelf! Hosted on Acast. See acast.com/privacy for more information.

In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Philip Lee, CEO at GeneFab. Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with Philip, covering: The role of luck in the development of his entrepreneurial journey of multiple biopharma start-ups Bootstrapping a biological tech company and then selling to Millipore, along with lessons learnt from a more prominent global organization Building a new company from the back of a napkin to an IPO on the NASDAQ Creating a technology platform and operational capability with real therapeutic application that led to the spin-out of Genefab Bridging the gap for early-stage cell therapy companies with aligned incentives and a non-transactional model Philip Lee is a bioengineer, biotechnology entrepreneur, and executive who has spent the last 20 years building companies and commercializing products, including cell and gene therapies, synthetic biology platforms, scientific instrumentation, cell culture systems, and advanced manufacturing services. He has been the “first employee” at multiple ventures with leadership experience across diverse growth trajectories, including bootstrapping, VC and PE funding rounds, IPO, acquisition, and internal innovation within a large enterprise. Philip holds degrees from the Massachusetts Institute of Technology and the UC Berkeley/UCSF Joint Graduate Program in Bioengineering. Philip is currently the founding CEO of GeneFab, a contract research, development, and manufacturing organization focused on supporting its clients in bringing innovative genetic medicines to needy patients.  Before GeneFab, Philip was the Co-Founder and CTO of Senti Biosciences, a cell and gene therapy company applying gene circuit technology to improve the efficacy and safety of cancer cell therapies. Philip was also the co-founder and CEO of Cellasic Corp, a microfluidics instrumentation company that MilliporeSigma had acquired. Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating! Molecule to Market is also sponsored and funded by ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.

In this episode of The Deep Life Podcast, hosts Dan and Elise delve into the concept of living deeply with a special focus on health and wellness through molecular hydrogen. Joining them is Greg, the Hydrogen Man, who shares his personal journey of overcoming severe health issues through hydrogen therapy. Greg explains the significance of molecular hydrogen as the 'life molecule,' its benefits for health and spirituality, and the best methods for obtaining and using hydrogen, including clean water protocols and machine recommendations. The discussion also covers the science behind hydrogen's potential to protect and heal the body, improve nutrient absorption, and even enhance the body's ability to absorb sunlight. Greg shares insights on the importance of clean water, daily protocols, and the fascinating overlap between hydrogen and spirituality. Tune in for an eye-opening conversation that blends science, health, and deep living.00:00 Introduction to the Deep Life Podcast01:00 Understanding and Loving Your Body02:33 Special Offer: Body and Soul Course02:52 Introduction to Molecular Hydrogen04:47 The Science and Spirituality of Hydrogen06:28 Hydrogen's Role in Health and Healing09:33 The Japanese Mastery of Water and Hydrogen18:01 Greg's Personal Health Journey27:22 Hydrogen's Impact on Various Health Conditions32:05 Hydrogen in Medical Emergencies39:56 Self-Experimentation and Blood Work Surprises41:36 The Quest for Clean Water46:32 The Importance of Fiber and Nutritional Deficiencies56:15 Hydrogen Protocols and Their Benefits58:37 The Impact of Contaminants in Water01:08:19 Daily Protocols for Optimal Health01:18:01 Final Thoughts and Future DirectionsYou can find Greg here:YouTube& access hydrogen water herehttps://holyhydrogen.com/Sign up for ‘Your  Body is the Portal to Your Soul' course from Iris Angellys here: https://www.irisangellys.com/members-programReceive 22% off this course by entering the discount code:   DEEPLIFE If you'd like to connect with Dan & EliseYou can find The DEEP Life on social mediaInstagram: https://bit.ly/3TTuUfWYouTube: https://bit.ly/3ScoOWSTikTok: https://bit.ly/3TOX0sUIf you'd like to connect with Dan:You can find him at MomentumStrengthWellness.comwhere he provides virtual fitness & holistic lifestyle coachingOr throughIG @MomentumStrengthWellnessYouTube @MomentumStrengthWellnessFacebook @MomentumStrengthWellness

In this fascinating episode, Jai sits down with scientist and entrepreneur Chris Burres, co-founder of MyVitalC, to explore the powerful potential of the carbon molecule ESS60, a Nobel Prize-winning discovery. Chris shares how this molecule—originally used in industrial applications—has shown promising results in extending lifespan, reducing inflammation, and supporting mitochondrial function.Together, they dive into:What ESS60 is and how it works in the bodyThe groundbreaking 2012 longevity study on ratsHow oxidative stress accelerates aging—and how ESS60 may combat itThe intersection of biohacking, mindfulness, and responsible supplementationThis is a must-listen for anyone curious about cutting-edge science in the service of graceful, vital aging.To Try MyVitalC:https://www.myvitalc.com/taam/Chris's Buress Podcast Page: www.LiveBeyondTheNorms.comChris's Book Page: www.LiveLongerAndBetterBook.comChris Burres Instagram: instagram.com/myvitalcJai's Instagram:@theartofagingmindfully@jaiyogashalaTO SUPPORT THE ART OF AGING MINDFULNESS PODCAST:patreon.com/jaisugrimHealth and Longevity Coaching with Jai:https://theartofagingmindfully.com/To Train with Jai in "Yoga for Longevity Classes:"https://jaiyogashala.com/daily-schedule/If you enjoyed this episode, please leave a review and share it with others who might benefit from these insights!

Welcome back to Beyond Limits! In this solo episode, Liv dives into the molecule that lets you quantum leap. This one's for the women asking, “How do I collapse time?”Key Takeaways:

What if the cure for Alzheimer's, heart disease, and erectile dysfunction already exists? Dr. Nathan Bryan breaks the silence on the missing molecule that could reverse disease.  Dr Nathan Bryan is a renowned nitric oxide biochemist, entrepreneur and author, who has researched nitric oxide for the past 18 years and made many seminal discoveries in the field. He is also the author of books such as, ‘The Secret of Nitric Oxide-Bringing The Science To Life'. In this conversation, Dr Nathan and Steven discuss topics such as, how doctors are trapped in a broken system, the link between oral infection and cancer, why blood pressure medicine doesn't work, and how nitric oxide can make you 15 years younger.  00:00 Intro 02:33 Nathan's Mission 04:38 Decline in Nitric Oxide (NO) Production 05:40 Symptoms of Low NO Levels 06:55 Diseases Linked to NO 08:21 What Prompted Nathan's Interest in NO? 10:35 Your Experience With Your Dad Setting You on This Path 12:07 Who Are You & Your Experience 13:14 Nitric Oxide Breakdown 14:24 Is Everything You See Just Aging? 16:07 How to Measure Vascular Age 17:50 Chronic Diseases Associated With NO Deficiency 21:54 The Medical Industry Is Broken 27:40 Doctors Are Trapped in the Broken System 29:18 The Molecule of Longevity 33:00 What Do You Think of Bryan Johnson? 34:38 Can NO Be Overdosed? 36:33 NO's Role in Increasing Telomere Length 38:33 Relationship Between NO and Oral Microbiome 40:54 Nathan's View on Antibacterial Products 44:04 Negative Impacts of Using Mouthwash 46:08 Oral Microbiome and Blood Pressure Connection 48:25 Link Between Oral Health and Cancer 54:10 Ads 56:19 How to Improve Our Oral Microbiome 58:21 Are Tongue Scrapers Beneficial for Oral Microbiome? 59:26 Relationship Between NO and Hormones 1:00:14 Should We Be Seeing Dental Hygienists? 1:00:45 Mouthwash Eliminates Benefits of Exercise 1:01:05 Foods to Boost Nitric Oxide Production 1:03:54 Wound-Healing Properties of NO 1:05:02 Foods for NO Production 1:05:36 *Beet the Odds*: Why Nathan Wrote a Book About Beetroots 1:09:06 Growth of Interest in Antacid Medication 1:12:22 Link Between NO Levels and Nasal Breathing 1:15:05 Humming Increases NO Levels 1:16:23 Things to Stimulate NO 1:17:45 The Future of Medicine Relies on This 1:20:01 Are You Happily or Unhappily Mated? Follow Dr. Nathan: Instagram - https://g2ul0.app.link/bRZbIr6ZtSb  YouTube - https://g2ul0.app.link/urFHgP9ZtSb  Website - https://g2ul0.app.link/AJpc3jc0tSb  You can purchase Dr Nathan's book, ‘The Secret of Nitric Oxide-Bringing The Science To Life', here: https://g2ul0.app.link/uHJ9hcf0tSb  Watch the episodes on Youtube - https://g2ul0.app.link/DOACEpisodes  Get your hands on the Diary Of A CEO Conversation Cards here: https://bit.ly/conversationcards-mp Independent research - https://nathanbryan.tiiny.co Sign up to receive email updates about Diary Of A CEO here: https://bit.ly/diary-of-a-ceo-yt  Ready to think like a CEO? Gain access to the 100 CEOs newsletter here: https://bit.ly/100-ceos-newsletter  Follow me: https://g2ul0.app.link/gnGqL4IsKKb  Sponsors: Perfect Ted - https://www.perfectted.com with code DIARY40 for 40% off Vivobarefoot - https://vivobarefoot.com/DOAC with code DOAC20 for 20% off Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Jodi Cook PhD, President and CEO at Skylark Bio. Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with Jodi, covering: How a curiosity for unanswered questions led her to a PhD and a career in biotech… and, ultimately, the magical, rare experience of getting a product to market The full-circle moment that took Jodi from being an audiologist to becoming the preclinical biotech CEO of a gene therapy company focused on curing pediatric deafness The reality of running a biotech company in the most challenging climate in a long time - and why she treats every dollar in the business as if it were her own Dress to impress - no-nonsense advice on crafting the impression you want to leave on your audience Why does she allow herself to dream of what Skylark can achieve as a business and the profound impact of gene therapies on patients? Jodi is an operationally focused business leader with experience across public and private biotechnology and medical device organizations. She brings a unique combination of scientific, clinical development, operational, and commercialization expertise to Skylark. Before leading Skylark, Dr. Cook was Senior Vice President of Gene Therapy Strategy at PTC Therapeutics. Before that, she served as the founding Chief Operating Officer of Agilis Biotherapeutics, overseeing its $1 billion acquisition. She earned her Ph.D. from Arizona State University, a Master's in Audiology from the University of South Carolina, and a Bachelor of Arts from Loyola University Maryland. She completed a fellowship at Johns Hopkins Medical School in Baltimore, Maryland. She is a Board Member of Fennec Pharmaceuticals and was previously Board Chair of STRM.BIO. Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating! Molecule to Market is also sponsored and funded by ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.  

Can you really reverse your biological age—and feel better than you did in your 30s? This week on Health Coach Talk, Dr. Sandi sits down with Leslie Kenny , Oxford-based CEO of Oxford Healthspan and co-founder of the Oxford Longevity Project, to explore the science of longevity, immune modulation, and one intriguing compound that's making waves in the wellness world: spermidine. Show notes: https://functionalmedicinecoaching.org/podcast/leslie-kenny-125/Leslie is offering Health Coach Talk listeners a special discount to try "Primeadine" at OxfordHealthspan.com with the code SANDI15.

In this episode of The Scope of Things, host Deborah Borfitz covers the latest news, including setting expectations for Phase II cancer trials, key learnings about dementia from the Nun Study, links between cardiovascular disease and mild cognitive impairment, using aspirin to prevent cancer spread, a clinical trial map to improve study access, and a naturally occurring molecule that rivals Ozempic in its weight loss potential. Deborah also speaks with Ravi Parikh, medical director of data and technology applications shared resource at Winship Cancer Institute of Emory University, about a novel AI platform he helped develop to translate clinical trial results to real world populations. News Roundup Phase 2 cancer drug trials Study in the Journal of the National Cancer Institute   Nun Study insights Review article in Alzheimer's & Dementia  DORIAN GRAY project Press release by the European Society of Cardiology Aspirin for preventing cancer spread Study in Nature  New clinical trial map  News announcement on the EMA website Molecule rivaling Ozempic Study in NatureThe Scope of Things podcast explores clinical research and its possibilities, promise, and pitfalls. Clinical Research News senior writer, Deborah Borfitz, welcomes guests who are visionaries closest to the topics, but who can still see past their piece of the puzzle. Focusing on game-changing trends and out-of-the-box operational approaches in the clinical research field, the Scope of Things podcast is your no-nonsense, insider's look at clinical research today.

This week,  we share our big awards weekend with you! Thanks to our title sponsors—Jersey Mike's, Werner Ladders and Molecule! We start our recap by joining our host Debbie Antonelli in Tampa at the 2025 Women's Final Four awards ceremony! WANT TO SUPPORT A TROPHY LIFE?Leave a rating and review on iTunes, Spotify, or wherever you get your podcasts. Your feedback only helps make the show better, and we appreciate your support! For more information about the Naismith Trophy Award, visit our home on the web.

In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Julien Laizé, Director External Manufacturing CTM at Valneva. Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with Julien, covering: Comparative views of being externally outsourced in large pharma's R&D vs a more action-oriented, small-med pharma company Taking us behind the scenes into in-housing vs outsourcing manufacturing decisions and CDMO identification... Why the selection process is becoming more and more challenging for buyers The importance of reputation and track record for CDMOs, and the value of being known as a specialist How do geopolitical issues and macro uncertainty play into the planning of external manufacturing?   Julien Laizé is a French/Italian executive with extensive and international experience in the vaccines and biologics industry. A Doctor of Pharmacy, Julien spent time at Siemens Healthineers, Novo Nordisk and Eli Lilly before joining Valneva, a specialty vaccine company focused on developing and commercializing prophylactic vaccines for infectious diseases with significant unmet medical needs.   Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating! Molecule to Market is also sponsored and funded by ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.

JACC Associate Editor Khurram Nasir, MBBS, FACC, speaks with author Michael J. Koren, MD, FACC, on his Featured Clinical Research study published in JACC and presented at ACC.25. This randomized, multicenter, double-blind, placebo-controlled, dose-ranging phase 2 study assessed efficacy, safety, and tolerability of AZD0780, a small molecule PCSK9 inhibitor. The study randomized 428 patients (426 started treatment) with hypercholesterolemia on standard-of-care statin therapy to daily oral administrations of AZD0780 1, 3, 10 or 30 mg, or matching placebo for 12 weeks. AZD0780 significantly reduced LDL-C levels versus placebo at all doses (from 35.3% to 50.7%) and demonstrated a safety and tolerability profile similar to placebo. These findings support further development of AZD0780 as part of a simple, oral regimen for lowering LDL-C beyond that achieved with statin therapy.

Angela talks to Leslie Kenny, about the fascinating world of longevity and health optimisation. Leslie, a renowned expert in the field, shares her personal journey of reversing her biological age to 21 at the age of 59, focussing upon the importance of a multifactorial approach to aging that includes diet, movement, sleep, and social connection. Together Angela and Leslie discuss the often-overlooked significance of sleep and social interactions, as well as the role of the microbiome in health. Leslie also introduces the powerful compound spermidine, found in various plant-based foods, and its benefits for autophagy, immune health, and even hair pigmentation KEY TAKEAWAYS Focus on diet, movement, sleep, and social connection to optimise health and longevity. Prioritising sleep is particularly crucial for reducing risks associated with Alzheimer's and dementia. Each individual has a unique microbiome influenced by their ancestry, which affects how they process different foods. Identifying and removing personal dietary "kryptonite" (foods that trigger negative responses) while incorporating beneficial foods is essential for optimal health. This compound, found in various plant-based foods, activates autophagy, a cellular renewal process. Increasing spermidine intake can support gut health, immune function, and even hair pigmentation by promoting the growth phase of hair follicles. Fasting can have different effects on men and women, particularly during perimenopause. Women may experience negative hormonal changes and stress responses from prolonged fasting, making it essential to find alternative ways to stimulate autophagy, such as through spermidine supplementation. BEST MOMENTS "Aging is a multifactorial problem, so it needs to be solved with a multifactorial approach. Focus on these four pillars: diet, movement, sleep, and social connection." "The more plants we can get into our diet, the better, both for fiber and because there are lots of polyphenols... spermidine activates that cell renewal process known as autophagy." "The greater the diversity of the gut biome, the healthier the person is, the more resilient the microbiome is and able to respond to challenges." "When we think about fasting... it isn't always suitable for women, particularly those in high-stress jobs or going through perimenopausal transition." VALUABLE RESOURCES Click here for discounts on all the products I personally use and recommend A BIG thank you to our sponsors who make the show possible: Oxford Healthspan: Target 9 out of the 12 Hallmarks of Aging with Oxford Healthspan Primeadine - and use code ANGELA to save 15% LVLUP HEALTH: Slow aging, repair gut health boost collagen and recovery and more with LVLUP Health’s amazing products. Save 15% with code ANGELA at https://lvluphealth.com/angela LUMEN: Develop metabolic flexibility and remove the guesswork with Lumen - use code ANGELA for your exclusive discount at http://angelafoster.me/lumen ABOUT THE GUEST Leslie’s Kenny is an Oxford-based, Harvard-educated CEO and patient advocate whose life took a dramatic turn in her late 30s when she was diagnosed with Lupus, Rheumatoid Arthritis, and Hashimoto’s Thyroiditis, told she had five years to live and that she could give up on having children. Refusing to accept this prognosis, she transformed her health by eliminating inflammatory triggers and supporting her body’s natural healing. Now 59, she has the biological age of 21, is autoimmune disease-free, and naturally conceived at 43. Empowered by her health journey, she returned to school, became a certified Bulletproof coach and began working with Oxford University scientists, helping them raise funding for their groundbreaking research. In a meeting with Professor Katja Simon, she discovered spermidine, a powerful, natural compound dubbed as an “anti-aging vitamin” and found to “delay aging in humans” through its ability to activate autophagy (cell renewal) and target key aging pathways. Recognizing its potential, she founded Oxford Healthspan, launching Primeadine®, a plant-derived spermidine supplement, with the highest quality, Japanese ingredients and the backing of top scientific and clinical advisors. She also collaborated with University of Oxford academics to co-found a non-profit organization, called the Oxford Longevity Project, dedicated to educating the public on easy, actionable ways to improve their healthspan and longevity. oxfordhealthspan.com lesliesnewprime.com oxfordlongevityproject.org https://www.instagram.com/oxfordhealthspan/ https://www.instagram.com/lesliesnewprime/ https://www.instagram.com/oxfordlongevityproject/ ABOUT THE HOST Angela Foster is an award winning Nutritionist, Health & Performance Coach, Speaker and Host of the High Performance Health podcast. A former Corporate lawyer turned industry leader in biohacking and health optimisation for women, Angela has been featured in various media including Huff Post, Runners world, The Health Optimisation Summit, BrainTap, The Women’s Biohacking Conference, Livestrong & Natural Health Magazine. Angela is the creator of BioSyncing®️ a blueprint for ambitious entrepreneurial women to biohack their health so they can 10X how they show up in their business and their family without burning out. The High Performance Health Podcast is a top rated global podcast. Each week, Angela brings you a new insight, biohack or high performance habit to help you unlock optimal health, longevity and higher performance. Hit the follow button to make sure you get notified each time Angela releases a new episode. CONTACT DETAILS Instagram Facebook LinkedIn Affiliate Disclaimer: Note this description contains affiliate links that allow you to find the items mentioned in this video and support the channel at no cost to you. While this channel may earn minimal sums when the viewer uses the links, the viewer is under no obligation to use these links. Thank you for supporting the show! Disclaimer: The High Performance Health Podcast is for general information purposes only and do not constitute the practice of professional or coaching advice and no client relationship is formed. The use of information on this podcast, or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be a substitute for medical or other professional advice, diagnosis, or treatment. Users should seek the assistance of their medical doctor or other health care professional for before taking any steps to implement any of the items discussed in this podcast.

Are you ready to uncover the secret to reversing biological age and boosting your midlife vitality? In this episode, Leslie Kenny takes us into the fascinating world of spermidine, a molecule that holds the key to managing menopause symptoms and enhancing overall health. How can this hidden molecule transform your sleep, skin, and hair health? Join us as we unravel the mysteries of menopause and explore the power of spermidine in maintaining youthful energy and balance. Can it truly reverse hair loss and improve sleep quality? Discover the unexpected ways this molecule supports cellular renewal and hormone regulation. What role does bioidentical hormone replacement therapy play alongside spermidine in promoting health and longevity? How can these strategies help you navigate the challenges of aging with grace and resilience? Get ready for a captivating journey into women's health biohacking! In this episode, we uncover: How Leslie defied medical odds and maintained a youthful biological age. Why spermidine is crucial for managing menopause symptoms and boosting cellular health. What unexpected benefits spermidine offers for hair growth, sleep, and hormone balance. How bioidentical hormone replacement therapy complements spermidine for menopausal support. Why sourcing spermidine from food-derived supplements is essential for safety and efficacy. Don't miss this episode filled with insights that could transform your health journey. Tune in to learn how you can harness the power of spermidine for a vibrant, ageless life!   Sponsors Get 15% off your Primadine purchase with coupon code KM15 here. Get 40% off your Cozy Earth bedding, pyjamas and more with coupon code HORMONES at cozyearth.com   Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada.   Visit karenmartel.com to explore our comprehensive programs: Bioidentical Hormone Replacement Therapy Individualized Weight Loss Programs  Peptide Therapy for weight loss    Interested in our NEW Peptide Weight Loss Program? Join today and get all the details here.   Join our Women's Peri and Post Menopause Group Coaching Program, OnTrack, TODAY!   To our nursing audience members, our podcasts qualify for nursing CE @ RNegade.pro. Provide # CEP17654.   Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert   Karen's Facebook Karen's Instagram

Lechler, Bernd www.deutschlandfunk.de, Corso

In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Jason C. Foster, Chief Executive Officer and Executive Director at Ori Biotech. Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with Jason, covering: How being frustrated by big company life led to the development of a business unit within Reckitt Benckiser that went on to be valued at $1bn The story of how a spin-out went on to list on the LSE with a cool $3.5bn market cap Taking his skills and experience before making 18+ healthcare start-up investments,... determined to add value beyond the cash Being wowed by the potential of CGTs and building the business he always wanted to work for in Ori The mission is to build enabling technology for power cell therapy companies and cut down the manufacturing costs by at least 50% to improve accessibility and affordability. Jason has held leading roles in consulting, healthcare and technology companies for over 20 years in the US, UK and Europe. He is CEO and Executive Director for Ori Biotech, a cell and gene therapy manufacturing technology start-up with offices in London and New Jersey. He raised a $100M Series B funding round in December 2022. Jason also serves as a Non-Executive Director of London-based health tech start-ups gripAble and Credentially and Auxita Pty, an Australian healthcare data platform. As the Managing Director of Health Equity Consulting, he has advised PE/VC funds, family offices, accelerators and healthTech start-ups.   Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating! Molecule to Market is also sponsored and funded by ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.

In this episode, I sit down with Dr. Emilia Vuorisalmi, a medical doctor, researcher, and bestselling author known as Finland's Love Doctor. We dive deep into the science of love, heartbreak, and hormonal balance, exploring how dopamine, serotonin, and oxytocin shape our emotions, relationships, and overall wellbeing.Dr. Vuorisalmi shares her personal journey of overcoming love addiction, revealing how heartbreak can physically manifest in the body—and more importantly, how to heal. We discuss somatic therapy, breathwork, meditation, and lifestyle changes that help reset the nervous system and bring balance to our love hormones.Topics Covered:✔️ How love and heartbreak impact our brain chemistry✔️ The science behind love addiction and how to break free✔️ Dopamine, serotonin, and oxytocin - what they really do✔️ How to use breathwork and meditation to heal from emotional pain✔️ The hidden dangers of dating apps and dopamine addiction✔️ Why boundaries are key to healthy relationships✔️ The power of manifestation, self-worth, and connection

"How a Single Chemical in Your Brain Drives Love, Sex, and Creativity – and Will Determine the Fate of the Human Race"

In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Ben Locwin, Chief Scientist, Head of Clinical Services and Project Sciences at Black Diamond Networks (BDN). Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with Ben, covering: Being part of the Lonza growth story in its 'scrappy' years Learning never to say no to a good opportunity and how that's opened many doors Becoming part of the more significant patient conversations at Biogen Dropping in seal teams to help companies do what they may never have achieved Why is change always inevitable in our sector, and what may the future hold for us all? As the saying goes, we're all a product of our growth and past experiences. Ben Locwin is an industry and healthcare executive who has been variously described as a "Remarkably talented speaker" by the Association for Talent Development, a "Rockstar epidemiologist" by NPR, a "healthcare futurist" by Contract Pharma and Rodman Media, and "a good friend" by ...his friends. He began his journey as an astrophysicist 30 years ago and then transitioned into the world of biotech in the 1990s when the nascent industry was yet poised to take over the world. He has specialized training as a neuroscientist and has worked with some of the top companies in the industry, both as a leader and a consultant. He has been a member of several Boards, association committees, steering teams, Task Forces, and scientific advisory panels. Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating! Molecule to Market is also sponsored and funded by ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.

In this episode of Molecule to Market, you'll go inside the outsourcing space of the global drug development sector with Matthew Bio, CSO, Cambrex & President, Snapdragon Chemistry Your host, Raman Sehgal, discusses the pharmaceutical and biotechnology supply chain with Matt, covering: The frustrating experience of not having ownership or being hands-on at big pharma middle management Recounting the early days of Snapdragon Chemistry and being in the right place at the right time to harness continuous process manufacturing Getting out of the way of your talented people to let them explore and shine The story behind how a proposed acquisition by Asymchem was blocked by the Treasury's Committee on Foreign Investment in the United States (CFIUS)... Deciding to choose and stay at Cambrex post-acquisition, and having the freedom to use Snapdragon as a catalyst for growth Matt began his career in chemistry more than 30 years ago developing continuous processes for the manufacture and purification of acrylates at the former Rohm & Haas company. Matthew then moved to Columbia University and earned a PhD in Chemistry. Upon graduating, Matthew returned to industry as a process development chemist at Merck Research Laboratories.  In 2006, Matthew moved to Amgen where he worked on the development of both batch and continuous manufacturing solutions for synthetic drug substances. He also worked on the development of new manufacturing technologies for synthetic – biologic hybrid molecules. In 2015, Matthew was a founding member Snapdragon Chemistry, Inc., a contract development firm specialized in continuous manufacturing technology. He is author or inventor on more than 30 peer-reviewed publications and patents, and numerous regulatory filings. Matthew is driven by a passion for the development of new chemical technologies. Please subscribe, tell your industry colleagues and join us in celebrating and promoting the value and importance of the global life science outsourcing space. We'd also appreciate a positive rating! Molecule to Market is also sponsored and funded by ramarketing, an international marketing, design, digital and content agency helping companies differentiate, get noticed and grow in life sciences.  

Join me as I explore this tiny yet incredibly powerful molecule that offers a plethora of health benefits. From its ability to manage inflammation and oxidative stress to enhancing exercise performance and recovery, molecular hydrogen is a fascinating subject in the realm of biohacking and longevity.    Hydrogen Products Mentioned: Hyest - https://www.hyestvitamins.com/?ref=LONGEVITY - Use Code: LONGEVITY for 10% off DrinkHRW - visit https://drinkhrw.com/superhuman use code LONGEVITY for 15% off   What We discuss: Hydrogen's Unique Properties ... 00:01:00 Hydrogen Supplementation Methods ... 00:04:30 Preferred Hydrogen Tablets ... 00:07:00 Research and Human Studies on Hydrogen ... 00:10:00 Selective Antioxidant and Anti-inflammatory Benefits ... 00:13:00 Exercise and Recovery Benefits ... 00:16:00 Cardiovascular Health Benefits ... 00:17:30 Neuroprotective Effects ... 00:20:00   Our Amazing Sponsor: BiOptimizers - Magnesium Breakthrough -  BiOptimizers: It's the only full-spectrum magnesium supplement with 7 unique forms of magnesium that your body can actually use and absorb. Go to  bioptimizers.com/bionat and enter the coupon code BIONAT to get 10% off your order.   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

This episode is brought to you by Levels and Fatty15. When we think about long-term health and longevity, nitric oxide production probably isn't the first thing that comes to mind. But today's guest explains why this crucial molecule plays a key role in our bodies—and the tell-tale signs of low production that can ultimately contribute to chronic disease. Today on The Dhru Purohit Show, Dhru sits down with Dr. Nathan Bryan to explore why nitric oxide is the holy grail of molecules for long-term health—and the top lifestyle factors that can make or break its production. Dr. Bryan ranks the biggest disruptors of nitric oxide, including alcohol, poor sleep, a sedentary lifestyle, ultra-processed foods, and chronic stress, and dives into the latest research on how they impact your body. He also breaks down the critical role nitric oxide plays in disease prevention, from chronic illness to Alzheimer's. If you're looking for a masterclass on how to boost nitric oxide production and what habits you need to tweak, this episode is a must-listen. Dr. Nathan Bryan is a renowned biomedical researcher known for his groundbreaking work on nitric oxide (NO) biology. Dr. Bryan's research has significantly advanced our understanding of NO's critical roles in cardiovascular health, immune function, and neurobiology. Beyond academia, he advocates for public health, translating his research into practical solutions for improving human health. His new book is The Secret of Nitric Oxide.  In this episode, Dhru and Dr. Bryan dive into: How alcohol impacts nitric oxide production (00:31) Why nitric oxide is crucial for health (03:12) The dangers of nicotine and smoking on nitric oxide (04:36) The controversy around seed oils (10:17) How dangerous are ultra-processed foods (18:43) How nitric oxide is created and what chronic stress does to production (26:10) Sedentary lifestyle and its impact on health risks (33:39) Nightly desserts and glucose monitoring (42:10) Intermittent fasting and the importance of meal personalization (50:15) Antiseptic mouthwash, bad breath, and the microbiome (54:09) Nitric oxide benchmarks and what test strips measure (58:50) Lack of optimal sun exposure (01:11:57) Eating nitrate-rich foods and carnivore diet concerns (01:15:14) Hydration's role in nitric oxide levels (01:21:27) Ibuprofen, inflammation, and nitric oxide (01:23:11) N101 products and final thoughts (01:29:22) Also mentioned in this episode: Dr. Nathan Bryan's book - The Secret of Nitric Oxide https://www.n101nutrition.com/ Try This-Firefighter Study For more on Dr. Nathan, follow him on Facebook, Instagram, X/Twitter, YouTube, and his Website. This episode is brought to you by Levels and Fatty15. Right now, Levels is offering my listeners an additional 2 FREE months of the Levels annual Membership when you use my link, levels.link/DHRU. Make moves on your metabolic health with Levels today.  Fatty15 is offering an additional 15% off its 90-day subscription Starter Kit. Go to fatty15.com/dhru and use code DHRU to replenish your C15 levels for long-term health. Learn more about your ad choices. Visit megaphone.fm/adchoices

Could a single molecule be the difference between vibrant longevity and early decline? Dr. Andy Salzman—Harvard-trained physician, scientist, and creator of the first PARP1 inhibitor—joins Dave to reveal the real key to living longer, fighting disease, and maximizing your energy: NAD. This master molecule fuels your mitochondria, DNA repair, and cellular resilience, but here's the catch—it plummets as you age. That means more fatigue, brain fog, inflammation, and higher risks of disease. But what if you could stop the decline and even reverse it? Dr. Salzman breaks down the game-changing science behind NAD, CD38, and cellular repair—and the fastest, most effective ways to optimize your levels for peak performance, health, and longevity. Get ready to rethink everything you thought you knew about aging, pharmaceuticals vs. supplements, and the radical new approach to living better, longer. What You'll Learn: • The #1 reason your NAD is disappearing—and how to fix it • Why NAD is the missing link in energy, DNA repair, and disease prevention • The hidden enzyme (CD38) that's sabotaging your longevity • How to supercharge mitochondria, optimize blood flow, and fight aging at the source • Why the supplement industry has it wrong—and the best way to boost NAD naturally • The shocking truth about the FDA, pharmaceuticals, and the future of anti-aging medicine Resources: • Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Andrew Salzman's Instagram – https://www.instagram.com/andrew_salzman/?hl=en • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey's Website: https://daveasprey.com • Dave Asprey's Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: 00:00 Trailer 01:07 Introduction and Episode Overview 02:29 Meet Dr. Andy Salzman 02:36 From Physician to Researcher 03:39 Pharmaceuticals vs. Nutritionals 04:17 The Role of NAD in Longevity 06:32 Challenges in Longevity Research 12:58 Understanding NAD and PARP 14:34 NAD's Impact on Health 23:19 Gut Health and Longevity 27:43 Innovations in NAD Supplementation 41:27 Customer Feedback and Product Effectiveness 42:41 Surprising Benefits of NAD for Sexual Health 44:47 NAD and Vascular Health 48:46 NAD's Role in Aging and Longevity 54:03 NAD and Lifestyle Choices 01:03:02 NAD and Cognitive Function 01:06:18 NAD and Exercise 01:13:42 NAD and Sleep 01:21:54 Final Thoughts on NAD and Longevity See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.