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Send us a textWelcome back to the @Storecreditpodcast live from @syndicatelosangeles. Store website | https://syndicatela.com/Gamma 11s & Gallery Vans Release | Another bad trade for the Custy? | SynCity EP203https://www.youtube.com/watch?v=Rs-IU4_llpQProduction by 88 Filmz ► https://www.instagram.com/88filmz_/ADD “Store Credit” ON INSTAGRAM ► https://www.instagram.com/storecredit...#sneakerpodcast #podcast #storecreditpodcast
The Celtics exploded in the 4th quarter to beat the Heat, 129-116. They hit a franchise record 10 threes in the final frame with Derrick White and Jaylen Brown both going for 30+ points. Chud and Doug break it all down, talk about Hugo's big night, the Heat's issues, Joe's wolf intrigue, and getting to know Bill Chisolm. Then they dive into the CP3 fiasco, the Emirates NBA Cup Finals, the latest WNBA news, and much more!00:00 Celtics' Recent Performance and Game Overview02:59 Game Analysis: Key Players and Strategies05:44 Jaylen Brown's Consistency and Impact09:02 Miami Heat's Current State and Future Prospects11:47 Celtics' Role Players and Defensive Strategies14:50 Injury Updates and Team Dynamics17:55 Final Thoughts on the Game and Future Outlook20:48 Franchise Records and Fan Favorites27:05 Behind the Scenes with Billy Banners30:07 The Future of the WNBA in New England37:55 Chris Paul's Leadership and the Clippers' Dilemma43:35 NBA Cup: A New Era of Competition46:02 Celtics and MVP Conversations52:53 NBA Recap: Exciting Games and Player Performances
In this episode of the Crypto 101 podcast, Brendan interviews Boris Bohrer-Bilowitzki, CEO of Concordium, discussing his journey into the crypto space, the current state of the market, and the unique approach Concordium takes towards identity and privacy in blockchain technology. They explore the challenges of crypto adoption, the importance of protocol level tokens, and the potential applications of Concordium in various sectors, including gaming and adult content. Boris emphasizes the need for a balance between privacy and regulatory compliance, and shares insights on the future of blockchain technology.Check out Gemini Exchange: https://gemini.comCheck out TruDiagnostic and use my code CRYPTO101 for a great deal: https://www.trudiagnostic.comCheck out Quince: https://quince.com/CRYPTO101Get immediate access to my entire crypto portfolio for just $1.00 today! Get your FREE copy of "Crypto Revolution" and start making big profits from buying, selling,Get immediate access to my entire crypto portfolio.. just $1.00 today! Go here to get access: https://www.crypto101insider.com/cryptnation-directm6pypcy1?utm_source=Internal&utm_medium=YouTube&utm_content=Podcast&utm_term=20250916Get your FREE copy of "Crypto Revolution: Your Guide To The Future of Money". In this book, I reveal how to make (and keep) a fortune during this crypto bull run! http://www.cryptorevolution.com/free?utm_source=Internal&utm_medium=YouTube&utm_content=Podcast&utm_term=20250916Chapters00:00 Introduction to Concordium and Its Vision02:20 Boris's Journey into Crypto and Blockchain05:14 Current State of the Crypto Market08:29 Challenges in Crypto Adoption11:17 Concordium's Unique Approach to Identity and Privacy14:21 Protocol Level Tokens and Their Importance17:24 Real-World Applications of Concordium20:19 The Future of Blockchain in Various Sectors23:11 Concordium's Milestones and Future GoalsMERCH STOREhttps://cryptorevolutionmerch.com/Subscribe to YouTube for Exclusive Content:https://www.youtube.com/@crypto101podcast?sub_confirmation=1Follow us on social media for leading-edge crypto updates and trade alerts:https://twitter.com/Crypto101Podhttps://instagram.com/crypto_101Guess Linkhttps://www.concordium.com/*This is NOT financial, tax, or legal advice*Boardwalk Flock LLC. All Rights Reserved ▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬Fog by DIZARO https://soundcloud.com/dizarofrCreative Commons — Attribution-NoDerivs 3.0 Unported — CC BY-ND 3.0 Free Download / Stream: http://bit.ly/Fog-DIZAROMusic promoted by Audio Library https://youtu.be/lAfbjt_rmE8▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬Our Sponsors:* Check out Quince: https://quince.com/CRYPTO101* Check out TruDiagnostic and use my code CRYPTO101 for a great deal: https://www.trudiagnostic.comAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy
Prior to the TKO purchase we discussed what Vince leaving WWE would mean. Let's go back to July of 2022 and see if we were right!Go AD-FREE Patreon.com/WWEPodcastBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-wwe-podcast--2187791/support.
On today's podcast, Brian and Mandy discuss the potential sale of Warner Brothers to Netflix and the implications for movie theater releases. They explore the new seasons of popular shows like 'Legend of Vox Machina,' and 'The Mighty Nein,' as well as the upcoming 'Welcome to Derry' prequel series. They also touch on the latest 'Doctor Who' spin-off and its delayed release in the US. The conversation covers the leaked 'Doomsday' trailer, the excitement surrounding 'Supergirl,' and fears around Paramount's hostile takeover attempt. Finally, they reflect on the abundance of quality geek TV and the challenges of keeping up with it all. The episode wraps up with thoughts on the uncertain future of streaming services and what it means for geek culture. 00:00 Introduction and Greetings 01:02 Warner Brothers and Netflix Deal 02:15 Amazon's Mighty Nine and HBO's Welcome to Derry 04:49 The War Between Land and Sea, but not for the US... 05:16 Disney's Delays and Leaks 10:23 James Gunn's Influence on DC 11:56 Hollywood's Current State and Future 15:37 Conclusion and Farewell
The UFC arrives in AEC. And we're live from the AEC Octagon.In the very first episode of our brand-new Bricks & Bytes Debates series, we are trading PR statements for sparring gloves. We're putting two industry heavyweights head-to-head to battle out one of the hottest topics in construction: Has AI actually solved estimating?In this no-holds-barred contester series, our contenders took the gloves off to represent the extreme Bull and Bear cases for Artificial Intelligence:• In the Red Corner: Mike "Mighty" Powers (Co-Founder, BuildVision), arguing that LLMs have solved the extraction problem and the industry needs to embrace the "Waymo" era of automation.• In the Blue Corner: Luigi "The Stinger" La Corte (Co-Founder, Provision), arguing that estimating is more than just counting symbols - and that without 100% accuracy, AI is still just a student driver.Moderated by the referee of reason, Patric "Praying For Exits" Hellermann, this debate moves through three grueling rounds: - Round 1: The Tech. Can LLMs actually count and measure complex drawings, or are they just guessing? - Round 2: The Accuracy Gap. Is 80% accuracy "good enough" to change the industry, or is "trust but verify" just a nice way of saying "do it yourself"? - Round 3: The Liability. In a world of design-bid-build, who takes the fall when the AI misses a scope gap? Tune in to uncover:• The "Waymo" Strategy: Why waiting for perfect AI is a mistake, and how to leverage the "self-driving" mindset to reduce takeoff times by 90% today.• The Hidden Liability Loophole: Why architects and engineers could solve the estimating crisis instantly by sharing models—and the legal reason they never will.• Symbols vs. Language: Learn the fundamental technical limitation preventing LLMs from reading 2D drawings like a human, and when we can expect "Visual Language Models" to catch up.• The Subcontractor's Dilemma: Why "Design Intent" matters more than counting linear feet, and why subs might actually be wasting time on granular takeoffs.• A "Bribe" for Better Data: One listener's hilarious (but practical) suggestion for how to finally get the Revit model from the design team.Who will deliver the knockout punch? Tune in to decide for yourself.Chapters 00:00 Intro01:48 Introduction to Bricks and Bytes Debates 04:07 Opening Statements and Context Setting 06:51 Technical Feasibility of AI in Estimating 09:57 Practical Applications and Limitations of AI 12:59 Customer Expectations and Accuracy in AI Solutions 15:57 The Role of Human Oversight in AI Estimation 18:43 Future of AI in Construction Estimation 38:23 Navigating the Self-Driving Debate 41:19 The Evolution of AI in Estimating 43:32 Trust and Liability in Construction 46:13 The Role of Liability in AI Adoption 49:22 The Future of Estimators in AI 53:34 Rebuttals and Admissions: A Critical Discussion 59:39 The Current State of AI in Estimating
In this 2025 Season Recap, Andy Roddick, Jon Wertheim, and Producer Mike dig into their “winners and unforced errors” of the tennis season: from successful US Open mixed doubles exhibition to the much-criticized extended Masters 1000 events. They debate the sport's failure to empower creators and players to use match footage, and the power struggle over prize money and revenue share at the Grand Slams. The crew also relives Sinner–Alcaraz's unforgettable Roland Garros epic, Coco Gauff's and Iga Świątek's seasons, Sabalenka's resilience, and the booming depth of American tennis on both tours. Finally, they zoom out to why tennis is “having a massive moment” globally and why that makes the structural mistakes and missed opportunities even more frustrating. COMMENT BELOW What was your biggest “winner” and “unforced error” of the 2025 tennis season?
In this episode of NucleCast, Adam talks with Dr. Byron Ristvet to discuss the complexities of nuclear testing, its historical context, and the current state of nuclear readiness. They delve into the types of nuclear tests, the role of various laboratories, and the controversial history surrounding Rocky Flats. The conversation highlights the importance of understanding nuclear policy and the implications of testing in today's geopolitical landscape.Currently, Dr, Ristvet is a consultant to Sandia National Laboratory and Lawrence Livermore National Laboratory for studies on nuclear test detection, and through Keystone International and MSTS, a consultant to LANL, DoE IN-1 and NNSA/NFO. He is a Senior Mentor in Sandia's Weapons Intern and Professional Development programs, and low yield nuclear monitoring research. Prior to his semi-retirement in February 2017, Dr. Ristvet was a senior subject matter expert (SME) to DTRA's Research and Development Directorate in the areas of nuclear and conventional weapons effects and testing, hard and deeply-buried-target characterization and defeat, counter-terrorism, cooperative threat reduction, knowledge preservation, nuclear test readiness, and to the Defense Threat Reduction Information Analysis Center. Prior to the underground nuclear testing (UGT) moratorium in 1992, he was the UGT containment scientist for the Defense Nuclear Agency. Based on his experience, he is an advisor to the U.S. intelligence community on foreign nuclear programs. Dr. Ristvet had a key role in DoD's Cooperative Threat Reduction efforts with the Russian Federation nuclear laboratories and the Kazakhstan National Nuclear Center. He is currently an Octant Associates consultant for DTRA nuclear proliferation prevention activities at the Semipalatinsk Test Site in Kazakhstan. Chapters00:00 Introduction to Nuclear Testing and Its Importance01:20 Understanding Nuclear Testing: Types and History05:38 Current State of Nuclear Testing and Readiness09:05 The Role of Laboratories in Nuclear Weapons Development13:34 Debunking Myths: The Rocky Flats Controversy18:27 Types of Nuclear Testing Conducted19:54 Key Takeaways and Future ConsiderationsSocials:Follow on Twitter at @NucleCastFollow on LinkedIn: https://linkedin.com/company/nuclecastpodcastSubscribe RSS Feed: https://rss.com/podcasts/nuclecast-podcast/Rate: https://podcasts.apple.com/us/podcast/nuclecast/id1644921278Email comments and topic/guest suggestions to NucleCast@anwadeter.org
In this episode, Dave and Dharm welcome back Ziad Nassar, Deputy CEO of Huspy, one year after his first appearance on the show. And what a difference a year makes. Ziad shares how Huspy has evolved from a UAE-based mortgage innovator into one of the fastest-scaling proptechs in EMEA, now active across the UAE and Spain with expansion under way in Saudi Arabia. Backed by a US $59 million Series B round led by Balderton Capital, Huspy is pursuing an ambitious mission: empowering the people who serve homebuyers and sellers. The conversation explores: Why Huspy focuses on enabling agents and mortgage brokers—the professionals closest to homebuyers and sellers—through technology, training, and fairer rewards. The logic behind expanding to Spain, and the company's disciplined playbook for entering new markets. How AI is transforming property discovery and agent productivity—from natural-language search (“find me a Georgian-style home near London with a vet nearby”) to smart tools that augment rather than replace human expertise. The importance of focus and discipline in scaling a startup, and the lessons Huspy has learned from trial, error, and relentless iteration. Why PropTech remains one of the least-disrupted global industries, and how human experience, data, and automation can finally start to change that. Ziad's candour and passion make this a compelling listen—an honest look at what it takes to modernise real estate, balance technology with trust, and build for the people who make the housing market work.
This week, Jason is joined by returning guest and one of the most influential leaders in real estate, Ryan Serhant! He is the co-founder and CEO of Serhant, now home to more than 1,500 agents with growth that has doubled year over year. He's built one of the most followed and powerful real estate brands in the world with over 9 million followers across all social media. Most importantly, he is back on Netflix with season two of Owning Manhattan, showing a more competitive, more ambitious and more strategic side as he expands his empire beyond Manhattan in battles in the most cutthroat luxury real estate market in the world. Ryan breaks down the current state of the real estate market and why the way people think about homeownership needs to evolve. He explains which markets remain stronger than ever, how banks are underwriting loans right now, and why it feels like everyone works for the government. Ryan shares his perspective on a potential rent freeze in New York, whether he'd ever consider going into politics, and the surprising parallel between divorce rates and the Fed lowering interest rates. He also unpacks the two largest referral sources in the U.S., why fear is often the only driver of lower prices, and how he approaches building trust in volatile markets. On the creative side, Ryan dives into creating a TV show no one has seen before, valuing the viewer's time, launching a new genre of reality TV with season two of Owning Manhattan, the movie that inspired part of the show's opening, and how Netflix checks compare to Bravo. He closes by sharing how he handles public attacks on his character, the four P's, and why choosing to be an open book has been central to his success. Ryan reveals all this and so much more in another episode you can't afford to miss! Host: Jason Tartick Co-Host: David Arduin Audio: John Gurney Guest: Ryan Serhant Stay connected with the Trading Secrets Podcast! Instagram: @tradingsecretspodcast Youtube: Trading Secrets Facebook: Join the Group All Access: Free 30-Day Trial Trading Secrets Steals & Deals! Quince: From Mongolian cashmere sweaters to Italian wool coats, Quince pieces are crafted from premium materials and built to hold up without the luxury markup. Get your wardrobe sorted and your gift list handled with Quince. Don't wait! Go to Quince.com/tradingsecrets for free shipping on your order and 365-day returns. Now available in Canada, too. Northwest Registered Agent: Northwest Registered Agent has been helping entrepreneurs launch and grow businesses for nearly 30 years. Build your business identity fast; and for just $39 plus state fees. Get an LLC, domain name, business email, local phone number, business address, registered agent, and compliance in just 10 clicks and 10 minutes. Visit www.northwestregisteredagent.com/paidtradingsecrets and start building something amazing! Momentous: Creatine isn't just for building muscle-it has become a daily essential for your strength, focus, recovery, aging, and cognitive performance, and now Momentous is making your daily Creatine routine even easier with NEW Creatine Chews - these bite-sized lemon lime chews make consistency effortless: you just chew and go. Go to livemomentous.com and use promo code TRADINGSECRETS for up to 35% off your first order. Yubico: Yubico's mission is simple: make the internet safer for everyone. Their breakthrough product, the YubiKey, is a small but powerful hardware key that protects your online accounts from phishing and hacks with just one tap. Trusted by millions, YubiKeys work across hundreds of services, from email and social media to banking, without the hassle of codes or passwords. Go to www.yubico.com/start to learn how to activate and set up your key.
Sir Richard Shirreff is Co-founder and Managing Partner at Strategia Worldwide. After graduating from Oxford, he served in the British Army for 37 years commanding soldiers on operations or in combat at every level from platoon to division and rising to the highest rank before retiring from the Army as NATO's Deputy Supreme Commander Europe. In 2016 his novel ‘2017: War with Russia' was published in the UK, USA, and Poland. He is an honorary Fellow of Exeter College, Oxford.----------LINKS:https://en.wikipedia.org/wiki/Richard_Shirreff https://twitter.com/RichardShirreff https://www.strategiaworldwide.com/our-people/sir-richard-shirreffhttps://www.globsec.org/who-we-are/our-people/gen-ret-sir-richard-shirreff https://www.brookings.edu/events/is-armed-conflict-with-russia-a-real-possibility/ ----------Silicon Curtain is a part of the Christmas Tree Trucks 2025 campaign - an ambitious fundraiser led by a group of our wonderful team of information warriors raising 110,000 EUR for the Ukrainian army. https://car4ukraine.com/campaigns/christmas-tree-trucks-2025-silicon-curtainThe Goal of the Campaign for the Silicon Curtain community:- 1 armoured battle-ready pickupWe are sourcing all vehicles around 2010-2017 or newer, mainly Toyota Hilux or Mitsubishi L200, with low mileage and fully serviced. These are some of the greatest and the most reliable pickups possible to be on the frontline in Ukraine. Who will receive the vehicles?https://car4ukraine.com/campaigns/christmas-tree-trucks-2025-silicon-curtain- The 38th Marine Brigade, who alone held Krynki for 124 days, receiving the Military Cross of Honour.- The 1027th Anti-aircraft and artillery regiment. Honoured by NATO as Defender of the Year 2024 and recipient of the Military Cross of Honour.- 104th Separate Brigade, Infantry, who alone held Kherson for 100 days, establishing conditions for the liberation of the city.- 93rd Brigade "Kholodnyi Yar", Black Raven Unmanned Systems Battalion ----------DESCRIPTION:Critical Analysis: European Security in the Face of Rising Russian AggressionIn this episode, co-founder and managing partner at Worldwide and former NATO Deputy Supreme Commander Europe, Sir Richard Shirreff, discusses the evolving geopolitical landscape with host Jonathan. The conversation dives into Russian strategies and the apparent shift in the U.S. stance on European security under Trump's administration. Shirreff and Jonathan analyse the recently released U.S. National Security Strategy, highlighting its lack of emphasis on China and Russia as threats and its focus on European institutions. They discuss how Trump's policies may be inadvertently aiding Putin's objectives by decoupling U.S. support from European security and undermining NATO. The episode underscores the need for Europe to bolster its resilience and unity independently. Shirreff emphasizes the necessity of leadership and clear strategies to face these challenges. They also delve into the implications of cognitive warfare, societal resilience, and the broader necessity for Europe to mobilize and prepare for potential threats. In the concluding segment, they highlight a fundraiser aimed at supporting Ukrainian soldiers by providing crucially needed vehicles.----------CHAPTERS:00:00 Introduction and Guest Background01:21 Russian Strategy and US National Security Policy03:36 NATO's Current State and Challenges06:09 Europe's Need for Self-Reliance10:07 Resilience and National Defense13:37 Potential Future Scenarios28:54 Call to Action and Conclusion----------SUPPORT THE CHANNEL:https://www.buymeacoffee.com/siliconcurtainhttps://www.patreon.com/siliconcurtain----------
In this episode, Jon G. Sanchez, Dwight Millard, and Cory Edge discuss the current state of the housing and stock markets, providing insights on how buyers can navigate the challenges of purchasing a home in a seller's market. They emphasize the importance of negotiation strategies, understanding seller motivations, and the impact of mortgage rates on home buying decisions. The conversation also touches on the stock market's performance and how it relates to the overall economic landscape, offering listeners valuable tips for making informed financial decisions.www.sanchezgaunt.comChapters00:00 Introduction to the Show and Market Overview01:55 Current State of the Housing Market04:50 Impact of Interest Rates on Mortgages07:56 Negotiation Strategies for Home Buyers10:58 Understanding HOA Implications12:51 Conclusion and Final Thoughts19:11 Upcoming Bowl Games and Coaching Changes19:39 Market Trends and Buyer Negotiation Strategies27:28 Market Reality Check: Inventory and Seller Motivation30:26 Emotional Discipline in Real Estate Decisions31:37 Long-Term Wealth Building Through Smart Buying33:31 Disclaimer
Welcome to yet another episode of Before the Box Score, where we discuss all things Mizzou Football. In this episode, Nate and Nathan discuss the current state of the program following signing day and the coaching carousel. They dive into Eli Drinkwitz's recent contract extension, the transfer portal, and Missouri's recognition in the SEC. The guys also cover Missouri's upcoming Gator Bowl against Virginia, highlighting the challenges and expectations for the team moving forward. ---------- Subscribe to Rock M+ for access to Mizzou insider info, discussion boards, special live podcasts just for subscribers, and more! You can follow members of today's show on Twitter @BurstaHurst & @NateGEdwards. Have a question for one of our podcasts? Leave a 5 star review with your question and that show just might answer it in an upcoming episode! Do you like Rock M Radio? Drop us a Review and be sure to subscribe to Rock M Radio on your preferred podcasting platform. Be sure to follow @RockMNation and @RockMRadio on Twitter. And if you aren't subscribed yet, please subscribe to our YouTube channel! Learn more about your ad choices. Visit megaphone.fm/adchoices
Glen Grant worked as a defence and reform expert in Ukraine working for the Ukrainian Institute for the Future. He is also a Senior Fellow in the UK Institute for Statecraft on Building Integrity Initiative countering Russian influence. Glen graduated from the Royal Military Academy Sandhurst, the Junior Staff Course Warminster and the Joint Staff Defence College at the Royal Naval College Greenwich. ----------LINKS:https://balticsecurity.eu/https://defence-blog.com/ukraines-defense-gaps-threaten-war-effort-says-expert/https://glenhoward.substack.com/p/episode-16-ukraine-at-war-military ----------Silicon Curtain is a part of the Christmas Tree Trucks 2025 campaign - an ambitious fundraiser led by a group of our wonderful team of information warriors raising 110,000 EUR for the Ukrainian army. https://car4ukraine.com/campaigns/christmas-tree-trucks-2025-silicon-curtainThe Goal of the Campaign for the Silicon Curtain community:- 1 armoured battle-ready pickupWe are sourcing all vehicles around 2010-2017 or newer, mainly Toyota Hilux or Mitsubishi L200, with low mileage and fully serviced. These are some of the greatest and the most reliable pickups possible to be on the frontline in Ukraine. Who will receive the vehicles?https://car4ukraine.com/campaigns/christmas-tree-trucks-2025-silicon-curtain- The 38th Marine Brigade, who alone held Krynki for 124 days, receiving the Military Cross of Honour.- The 1027th Anti-aircraft and artillery regiment. Honoured by NATO as Defender of the Year 2024 and recipient of the Military Cross of Honour.- 104th Separate Brigade, Infantry, who alone held Kherson for 100 days, establishing conditions for the liberation of the city.- 93rd Brigade "Kholodnyi Yar", Black Raven Unmanned Systems Battalion ----------DESCRIPTION:Glenn Grant on Ukraine's War: An In-Depth Analysis of Current Geopolitical DynamicsIn this episode, we revisit a conversation with Glen Grant, a defense and reform expert in Ukraine. The discussion highlights the current critical juncture in the Ukraine-Russia conflict, exploring the perceived flip-flopping of U.S. policy favoring Russia under the Trump administration. Glen shares insights on Trump's consistent pro-Russian stance, the potential oligarchic influences guiding global politics, and the effectiveness of Zelensky's leadership. The conversation delves into the operational and strategic challenges facing Ukraine, including issues in human resources, technology adoption, and military procurement. The episode emphasizes the role of civic society in Ukraine's defense efforts and the broader implications for Western defense strategies. Finally, the video includes a segment encouraging donations for purchasing life-saving vehicles for Ukrainian forces.----------CHAPTERS:00:00 Introduction and Guest Background01:12 Current State of the War and US Policy02:16 Trump's Influence and Russian Strategy05:52 Global Oligarchy and Political Manipulation20:19 Ukraine's Internal Challenges25:48 Western Military Preparedness and Drone Warfare37:18 Conclusion and Fundraising Appeal----------SUPPORT THE CHANNEL:https://www.buymeacoffee.com/siliconcurtainhttps://www.patreon.com/siliconcurtain----------TRUSTED CHARITIES ON THE GROUND:Save Ukrainehttps://www.saveukraineua.org/Superhumans - Hospital for war traumashttps://superhumans.com/en/UNBROKEN - Treatment. Prosthesis. Rehabilitation for Ukrainians in Ukrainehttps://unbroken.org.ua/Come Back Alivehttps://savelife.in.ua/en/Chefs For Ukraine - World Central Kitchenhttps://wck.org/relief/activation-chefs-for-ukraineUNITED24 - An initiative of President Zelenskyyhttps://u24.gov.ua/Serhiy Prytula Charity Foundationhttps://prytulafoundation.orgNGO “Herojam Slava”https://heroiamslava.org/kharpp - Reconstruction project supporting communities in Kharkiv and Przemyślhttps://kharpp.com/NOR DOG Animal Rescuehttps://www.nor-dog.org/home/----------
This episode we look at the current card markets. We talk about Youtube card content, & NCAA Basketball Men & Women. SCL HC S7E40
Watch on YouTube → https://www.youtube.com/watch?v=VU65vnqkBmE When two of the world's leading ALS researchers meet for the first time on a podcast, something remarkable happens. Dr. Merit Cudkowicz - Tim's close friend and arguably the world's foremost ALS expert, returns to Nothing Left Unsaid for her third appearance, this time joined by Dr. Tanya Daigle from the Allen Institute, who's pioneering genetic tools that could transform how we treat neurodegenerative diseases. Together, they reveal a future for ALS research that's closer than most people realize. This isn't your typical medical conversation. Merit and Tanya speak with unguarded hope about gene therapies that have stopped disease progression in 40% of patients, AI-driven drug discovery that's accelerating at unprecedented rates, and precision targeting tools that could deliver treatments directly to dying motor neurons without invasive brain surgery. They discuss the real bottlenecks between laboratory breakthroughs and patient impact, why most ALS drug trials aren't actually failures, and how the field has evolved from a handful of researchers to a global collaborative effort spanning continents. CHAPTERS: 00:00 Trailer01:09 Intro02:55 Current State of ALS Research05:19 Misconceptions About ALS09:32 Progress and Future of ALS Treatments21:17 Innovations in Genetic Tools for ALS31:59 A New Frontier in ALS Research35:03 Efficiency of Platform Trials in ALS Research36:59 The Importance of Funding and Science Collaboration37:55 Advancements in Treating ALS Smarter38:52 The Role of Biomarkers and Individualized Therapies41:31 Dream Trials and Future Prospects48:01 The Impact of AI in ALS Research54:08 The Next Big Pivot in ALS Research58:18 Hope and Collaboration in ALS Research01:01:04 How to Be Part of ALS Community RESOURCES & LINKS: Allen Institute: https://alleninstitute.orgHealey & AMG Center for ALS at Mass General: https://www.massgeneral.org/neurology/als SPONSORS:ElevenLabs: Thanks to ElevenLabs (https://elevenlabs.io) for supporting this episode and powering Tim's voice. SOCIAL:Website: https://nlupod.com/X: https://x.com/nlutimgreenFacebook: https://www.facebook.com/NLUpodInstagram: https://www.instagram.com/nlupod LISTEN ON OTHER PLATFORMS: Apple Podcasts: https://podcasts.apple.com/us/podcast/nothing-left-unsaid/id1734094890Audible: https://www.audible.com/podcast/Nothing-Left-Unsaid/B0CWTCRKGZCastbox: https://castbox.fm/channel/id6405921?country=usOvercast: https://overcast.fm/itunes1734094890iHeartRadio: https://www.iheart.com/podcast/263-nothing-left-unsaid-155769998/ PERSONAL: Tackle ALS: https://www.tackleals.comTim Green Books: https://authortimgreen.comTim's New Book - ROCKET ARM: https://www.amazon.com/dp/0062796895/ Learn more about your ad choices. Visit megaphone.fm/adchoices
Alex Payne and Mike Tindall dive into the seismic news of ITV securing the rights to the New Nations Series from 2026-2028, making them the undisputed home of English international rugby. Next year will be the first time in 30 years that all England games will be free to air. We ask… Is this the best thing to happen to the English game since 2003? Is rugby finally ready to grasp the opportunity of free-to-air coverage to widen the sport's appeal. We're joined by Ben Rumsby, Sports Investigations Reporter for The Daily Telegraph, for a deep dive into the state of the sports broadcasting landscape. Plus, England Sevens legend Ollie Phillips dials in to share the truly bonkers challenge he's about to undertake: rowing 3,000 miles across the Atlantic for three incredible causes (Cure Parkinson's, My Name's Dottie, and the Matt Hampson Foundation). Good luck, Ollie! 00:00
Mike shares his thoughts on the current state of the economy including healthcare affordability.
We're taking a break from our regularly scheduled programming for the holidays to bring you something a bit different: a foundational episode that covers everything you need to know about ketamine therapy in one comprehensive resource.Sam originally delivered this presentation to the UCLA and Betty Ford Addiction Medicine Fellowship, and it's become one of those episodes that medical professionals, curious physicians, and anyone seriously exploring this field have come back to. It covers ketamine's complete story, from its fascinating medical history to current research and real-world implementation protocols.Whether you're considering ketamine therapy for your own practice, trying to understand this rapidly evolving field, or just want a solid clinical foundation, this is your starting point. We bridge the gap between academic research and practical clinical application, breaking down complex pharmacology and patient selection in a way that's actually accessible.This is part of our "Episodes from the Vault" series, bringing back content that continues to serve as a go-to resource for healthcare providers across specialties. For those who may recall, this was originally released as Episode 31. The presentation format lets us go deep on each topic while keeping everything practically relevant for actual clinical decision-making.This episode is especially valuable if you're evaluating ketamine therapy integration, seeking to understand the evidence base, or looking to enhance your patient education and staff training.What You'll Learn in This Episode・Ketamine's journey from battlefield anesthetic to breakthrough mental health treatment・Evidence-based mechanisms of action and clinical research findings・Practical patient selection criteria, dosing protocols, and safety considerations for clinical practiceEpisode 46 show notes:00:00 - Teaser - Mental health crisis statistics and ketamine's role00:27 - Introduction to Episodes from the Vault series01:19 - Sam's presentation introduction and off-label use disclosure01:52 - Presentation Overview: Three-part structure: mental health/history, mechanisms/studies, patient selection/protocols02:19 - Part 1: Current State of Mental Health - Depression, PTSD, anxiety statistics and the need for ketamine therapy04:07 - The Need for More Treatment Options: Healthcare arsenal expansion with ketamine04:20 - A Brief History of Ketamine: From phencyclidine to FDA approval and Vietnam War battlefield use09:36 - Part 2: How Ketamine Works - NMDA receptor mechanisms and neuroplasticity effects12:11 - Types of Patient Ketamine Experiences: Four levels of non-ordinary states of consciousness14:49 - A Review of Scientific Studies: Yale study through recent research and meta-analyses22:43 - Part 3: Ideal Patient Selection, Dosing & Scheduling: Contraindications, protocols, and safety considerations32:33 - Episode wrap-up with YouTube resources, and moreThanks for listeningSelected Related Links:・For original Youtube version featuring slides during the presentation, go to https://youtu.be/u9XOQ2xnwsg・For references and studies mentioned in this episode, go to www.ketaminestartup.com/podcast/episode-046Follow us onLinkedinKetamine StartUp WebsiteYouTube
Director at Red Bridge Group Australia, Kos Samaras joined 3AW Mornings to discuss the latest political polling.See omnystudio.com/listener for privacy information.
Andy Baskin and Jeff Phelps give their thoughts on the state of college sports.
Andy Baskin and Jeff Phelps give their thoughts on the state of college sports and are joined by 92.3 The Fan Browns beat reporter Daryl Ruiter.
This week on The Beat, CTSNet Editor-in-Chief Joel Dunning spoke with Dr. Christopher McGregor, professor in the Department of Surgery at the University of Minnesota Twin Cities, about the current state of cardiac and kidney xenotransplantation. Chapters 00:00 Intro 03:10 Sir Terence English 08:00 JANS 1, Cardiac Xenotransplantation 09:13 JANS 2, Coffee Consumption on AF 11:06 JANS 3, Environmental Factors Acute AD 12:49 JANS 4, PROTHOR Trial 15:15 Video 1, Combined AV & Coronary via LAM 17:08 Video 2, ARCA w MV Prolapse 19:32 Video 3, Redo Elephant Trunk After EAR 22:06 Chris McGregor Interview 48:23 Upcoming Events 50:15 Closing They discussed the three approved trials for xenotransplantation in 2025, the preclinical efficacy assessment, and the various challenges of xenotransplantation. Additionally, they explored the history of orthotopic transplants, heart failure, and antibody-mediated rejection. They also examined the future of xenotransplantation and the anatomy of pig hearts vs human hearts. Joel also highlights recent JANS articles on the status of cardiac xenotransplantation including preclinical models, the DECAF randomized clinical trial on if caffeinated coffee consumption or abstinence reduces atrial fibrillation; the impact of environmental factors on acute aortic dissection; and a multicenter, international, randomized, controlled, phase 3 trial on the effects of intraoperative higher vs lower positive end-expiratory pressure during one-lung ventilation for thoracic surgery on postoperative pulmonary complications (PROTHOR). In addition, Joel explores combined aortic valve and coronary surgery via left anterior minithoracotomy, management of anomalous right coronary artery in a patient with mitral valve prolapse, and redo frozen elephant trunk after endovascular arch repair. Before closing, Joel highlights upcoming events in CT surgery. JANS Items Mentioned 1.) 2025: Status of Cardiac Xenotransplantation Including Preclinical Models 2.) Caffeinated Coffee Consumption or Abstinence to Reduce Atrial Fibrillation: The DECAF Randomized Clinical Trial 3.) Weathering the Aorta: The Impact of Environmental Factors on Acute Aortic Dissection 4.) Effects of Intraoperative Higher Versus Lower Positive End-Expiratory Pressure During One-Lung Ventilation for Thoracic Surgery on Postoperative Pulmonary Complications (PROTHOR): A Multicentre, International, Randomised, Controlled, Phase 3 Trial CTSNet Content Mentioned 1.) Combined Aortic Valve and Coronary Surgery via Left Anterior Minithoracotomy: Clinical Experience With Sutureless Bioprosthesis 2.) Management of Anomalous Right Coronary Artery in a Patient With Mitral Valve Prolapse 3.) Redo Frozen Elephant Trunk After Endovascular Arch Repair Other Items Mentioned 1.) Resident Video Competition 2.) 2025 CTSNet Recruitment Guide 3.) Career Center 4.) CTSNet Events Calendar Disclaimer The information and views presented on CTSNet.org represent the views of the authors and contributors of the material and not of CTSNet. Please review our full disclaimer page here.
What It Feels Like to Lead the World's Most Successful Musical with Maggie Brohn ---------------------------- She started answering phones. Now she runs Broadway's biggest global hit. Meet Maggie Brohn, the powerhouse behind Hamilton. In this episode of Heartbeat for Hire, host Lyndsay Dowd sits down with Maggie Brohn, Chief Operating Officer of Adventureland and the powerhouse Executive Producer of Hamilton across Broadway, the West End, Disney+, multiple global tours, and international productions. Maggie shares the remarkable story of how she went from answering phones in a theatrical office to becoming an owner, producer, and one of the most influential leaders in modern theater. She breaks down how Hamilton transitioned from a groundbreaking production into a global business — operating more like a major corporation than a traditional Broadway show. We explore the art of leading creatives, building trust, setting authority, navigating strong emotions, and making mission-critical decisions. Maggie reveals what it takes to guide artists while staying grounded in business realities and cultivating a team capable of worldwide excellence. She also opens up about listening, cultural sensitivity, DEI conversations, building long-term contracts, and why the industry needs a full reset. Plus, Maggie shares what Broadway needs most right now — and how audiences can help. Timestamps 00:00:00 Intro: The Audience's Desire for Delight in Theater 00:01:00 Introducing Maggie Brohn: Broadway's Executive Producer and COO 00:01:58 Maggie's Journey: From Answering Phones to Producing Hamilton 00:03:23 Leading Creatives: Setting Authority and Navigating Feelings 00:04:30 The Power of Trust and Delegating to Expertise 00:06:00 The Biggest Lesson: Moving Theater from "Show" to Global Business 00:08:15 Adapting Hamilton for International Audiences 00:11:59 The Current State of the Broadway Business 00:18:24 Setting Boundaries as a Manager 00:20:32 An Early Leadership Test: The Jack Daniels & Massage Request 00:23:46 Leading as an Outsider and a Woman in a Male-Dominated Group 00:24:49 Listening & Hard DEI Conversations 00:26:50 Maggie's Legacy: Leading an Industry "Reset" 00:30:22 Union Negotiations & Long-Term Contracts 00:33:26 How to Support Theater & Broadway Today 00:34:18 Conclusion & Final Thoughts About the Guest Maggie Brohn is the Chief Operating Officer of Adventureland and the Executive Producer of Hamilton on Broadway, the West End, the international tour, UK/Ireland Tour, and Disney+. Her recent credits include The Nightmare Before Christmas Light Trail at New York Botanical Garden, the 2023 Sweeney Todd Broadway revival, Hamilton in Hamburg and Australia, Derren Brown: Secret, and The Cher Show. Previously a partner at Bespoke Theatricals, Maggie general-managed major plays and musicals for over a decade. She serves on the Board of Governors and Executive Committee for The Broadway League and is a former Co-Chair of the Labor Committee. She resides in New York City with her husband and two children. About the Host – Lyndsay Dowd is a Speaker, Founder, Author, Coach, Podcast Host—and unapologetic Disruptor. With 30 years of leadership experience, including 23 at IBM, she's built and led high-performing teams that consistently delivered results. She also served as a Guest Lecturer at Harvard University, sharing her insights on modern leadership and culture transformation. As the founder of Heartbeat for Hire, Lyndsay helps companies ditch toxic leadership and build irresistible cultures that drive performance, retention, and impact. She's been featured in Fortune Magazine, HR.com, ABC, NBC, FOX, CBS, and over 100 podcasts. Lyndsay is a two-time best selling author of Top Down Culture and Voices of Women, and the host of the globally ranked and 2X awarded Heartbeat for Hire podcast—sitting in the top 2.5% worldwide. She is also the host of a weekly live show called THE LEADERSHIP LOUNGE. Lyndsay is a frequent speaker, moderator, and guest, known for her candor, humor, and ability to spark action. Official Brand Partner: https://MyDeals.Page/19c3 To my loyal listeners - I love luxury and I love a great deal. If you are looking for an amazing gift or a way to treat yourself, Go to https://cozyearth.com/ and use the code LEADWITHHEART and get 41% off. It's the deepest discount you will find anywhere and I get commission too! This brand has been on Oprah's Favorite Things 9 times!! Happy Shopping! Connect with Lyndsay Dowd: Website: https://heartbeatforhire.com LinkedIn: https://www.linkedin.com/in/lyndsaydowdh4h/ Instagram: https://www.instagram.com/lyndsaydowdh4h/ Facebook: https://www.facebook.com/LyndsayDowdH4H Tiktok: https://www.tiktok.com/@lyndsaydowdh4h #Hamilton #Broadway #MaggieBrohn #HamiltonMusical #ExecutiveProducer #LeadershipPodcast #CreativeLeadership #TheaterBusiness #WomenInLeadership #BehindTheScenes #HeartbeatForHire
Ryan Oliver and Chase Carroll return to discuss their thoughts on the current state of the Washington Wizards at about the quarter of the season through. Ryan and Chase deep dive into their thoughts on each of the players of the Wizards young core, and where they stand on each 20 games into the 25 season.Would they take a chance on any distressed asset currently potentially on the market?
Badgers worst season in 35 years comes to an end with a 17-7 loss to the Minnesota Golden Gophers. Another year without the Axe for the Badge... Yet the entire leadership is coming back? Alex and KJ dive into the predicament and offer fans words of hope in these dark times. Welcome back to the IKE Badgers Podcast! Subscribing, leaving a five-star review on the Apple Podcasts, and telling a friend is the #1 way to help the show.Follow IKE Badgers on Twitter for Live-Tweeting of Badgers Football @IKE_BadgersFan of the music? Stream "IKE Music" on Spotify
Week 13 of the NFL regular season is in the books! Time to talk about the big upsets in the NFL after Week 13, the game of the week, and an MVP update. That and other news and notes surrounding the NFL, including other burning topics in the game of football. There are questions to ask around the league, and that's what happens on this episode with hosts Jeff Hartman and Coach KT Smith as they dive head-first into the topics surrounding the NFL! This podcast is a proud member of the Pro Football Insiders. Learn more about your ad choices. Visit megaphone.fm/adchoices
In episode 62 of Going anti-Viral, Dr Rochelle Walensky joins host Dr Michael Saag on World AIDS Day 2025 to discuss her experience as the Director of the Centers for Disease Control and Prevention (CDC) during the COVID-19 pandemic and the current state of public health in the United States. Dr Walensky is a Professor of Medicine at Harvard Medical School and has published over 300 research articles that have motivated changes to US HIV testing and immigration policy and promoted expanded funding for HIV-related research, treatment, and the President's Emergency Plan for AIDS Relief (PEPFAR). Dr Walensky reflects on her experience during the early months of the COVID-19 pandemic in Massachusetts where she was the Chief of the Division of Infectious Diseases at Massachusetts General Hospital. Dr Saag and Dr Walensky then discuss her transition to the Director of the CDC and her management of the agency during the pandemic. Dr Walensky and Dr Saag emphasize the dedication of public health professionals and the need for continued support and understanding of the challenges they face. They discuss the risk of proposed budget cuts to the CDC and the impacts this will have on the agency as well as state and local public health departments. Finally, they discuss the future of public health and their shared optimism for public health over the long-term.0:00 – Introduction1:41 – Management of the early outbreak of COVID-19 in Massachusetts and reflections on the Conference on Retroviruses and Opportunistic Infections (CROI) in March of 202011:50 – Transition to lead the CDC and reflections on the difficult job of management of the CDC during a pandemic24:00 – Navigating COVID-19 variants and the challenge of public health recommendations for wearing masks and vaccination28:24 – Outlook on the future of public health and the CDC and the risks of proposed budget cuts on state and local public health agencies __________________________________________________Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral's host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode.Follow Going anti-Viral on: Apple Podcasts YouTubeXFacebookInstagram...
In this episode of the Casual Cattle Conversations podcast, Shaye sits down with Tim Petry from North Dakota State University to discuss the intricacies of the current cattle markets. The conversation covers producer-submitted questions, providing insights on price trends, the impact of global markets, and the future outlook for the cattle industry. Tim sheds light on the importance of sticking to traditional marketing plans, the volatility in the futures market, and the factors influencing the high demand and low supply scenario. He also shares valuable resources for producers to stay updated. Tune in for a comprehensive discussion aimed at helping producers make informed decisions in a fluctuating market. Get the resources mentioned in this episode here: https://bit.ly/CCC-resources Learn more about Profit Foundations for Ranchers here: https://www.casualcattleconversations.com/profit-foundations-for-ranchers Order your flavor of Pluck here: https://eatpluck.com/?ref=SHAYEWANNER 00:42 Meet Tim Petry: Cattle Market Expert 03:38 Current State of the Cattle Market 10:54 Producer Questions: Beef Prices and Market Trends 15:53 Global Cattle Herds and Future Market Predictions 23:24 Strategies for Producers in a Volatile Market 30:11 Resources and Current Events 39:15 Conclusion and Listener Support
IP Fridays - your intellectual property podcast about trademarks, patents, designs and much more
I am Rolf Claessen and together with my co-host Ken Suzan I am welcoming you to episode 169 of our podcast IP Fridays! Today's interview guest is Prof. Aloys Hüttermann, co-founder of my patent law firm Michalski Hüttermann & Partner and a true expert on the Unified Patent Court. He has written several books about the new system and we talk about all the things that plaintiffs and defendants can learn from the first decisions of the court and what they mean for strategic decisions of the parties involved. But before we jump into this very interesting interview, I have news for you! The US Patent and Trademark Office (USPTO) is planning rule changes that would make it virtually impossible for third parties to challenge invalid patents before the patent office. Criticism has come from the EFF and other inventor rights advocates: the new rules would play into the hands of so-called non-practicing entities (NPEs), as those attacked would have few cost-effective ways to have questionable patents deleted. The World Intellectual Property Organization (WIPO) reports a new record in international patent applications: in 2024, around 3.7 million patent applications were filed worldwide – an increase of 4.9% over the previous year. The main drivers were Asian countries (China alone accounted for 1.8 million), while demand for trademark protection has stabilized after the pandemic decline. US rapper Eminem is taking legal action in Australia against a company that sells swimwear under the name “Swim Shady.” He believes this infringes on his famous “Slim Shady” brand. The case illustrates that even humorous allusions to well-known brand names can lead to legal conflicts. A new ruling by the Unified Patent Court (UPC) demonstrates its cross-border impact. In “Fujifilm v. Kodak,” the local chamber in Mannheim issued an injunction that extends to the UK despite Brexit. The UPC confirmed its jurisdiction over the UK parts of a European patent, as the defendant Kodak is based in a UPC member state. A dispute over standard patents is looming at the EU level: the Legal Affairs Committee (JURI) of the European Parliament voted to take the European Commission to the European Court of Justice. The reason for this is the Commission’s controversial withdrawal of a draft regulation on the licensing of standard-essential patents (SEPs). Parliament President Roberta Metsola is to decide by mid-November whether to file the lawsuit. In trademark law, USPTO Director Squires reported on October 31, 2025, that a new unit (“Trademark Registration Protection Office”) had removed approximately 61,000 invalid trademark applications from the registries. This cleanup of the backlog relieved the examining authority and accelerated the processing of legitimate applications. Now let's jump into the interview with Aloys Hüttermann: The Unified Patent Court Comes of Age – Insights from Prof. Aloys Hüttermann The Unified Patent Court (UPC) has moved from a long-discussed project to a living, breathing court system that already shapes patent enforcement in Europe. In a recent IP Fridays interview, Prof. Aloys Hüttermann – founder and equity partner at Michalski · Hüttermann & Partner and one of the earliest commentators on the UPC – shared his experiences from the first years of practice, as well as his view on how the UPC fits into the global patent litigation landscape. This article summarises the key points of that conversation and is meant as an accessible overview for in-house counsel, patent attorneys and business leaders who want to understand what the UPC means for their strategy. How Prof. Hüttermann Became “Mr. UPC” Prof. Hüttermann has been closely involved with the UPC for more than a decade. When it became clear, around 13 years ago, that the European project of a unified patent court and a unitary patent was finally going to happen, he recognised that this would fundamentally change patent enforcement in Europe. He started to follow the legislative and political developments in detail and went beyond mere observation. As author and editor of several books and a major commentary on the UPC, he helped shape the discussion around the new system. His first book on the UPC appeared in 2016 – years before the court finally opened its doors in 2023. What fascinated him from the beginning was the unique opportunity to witness the creation of an entirely new court system, to analyse how it would be built and, where possible, to contribute to its understanding and development. It was clear to him that this system would be a “game changer” for European patent enforcement. UPC in the Global Triangle: Europe, the US and China In practice, most international patent disputes revolve around three major regions: the UPC territory in Europe, the United States and China. Each of these regions has its own procedural culture, cost structure and strategic impact. From a territorial perspective, the UPC is particularly attractive because it can, under the right conditions, grant pan-European injunctions that cover a broad range of EU Member States with a single decision. This consolidation of enforcement is something national courts in Europe simply cannot offer. From a cost perspective, the UPC is significantly cheaper than US litigation, especially if one compares the cost of one UPC action with a bundle of separate national cases in large European markets. When viewed against the territorial reach and procedural speed, the “bang for the buck” is very compelling. China is again a different story. The sheer volume of cases there is enormous, with tens of thousands of patent infringement cases per year. Chinese courts are known for their speed; first-instance decisions within about a year are common. In this respect they resemble the UPC more than the US does. The UPC also aims at a roughly 12 to 15 month time frame for first-instance cases where validity is at issue. The US, by contrast, features extensive discovery, occasionally jury trials and often longer timelines. The procedural culture is very different. The UPC, like Chinese courts, operates without discovery in the US sense, which makes proceedings more focused on the written record and expert evidence that the parties present, and less on pre-trial disclosure battles. Whether a company chooses to litigate in the US, the UPC, China, or some combination of these forums will depend on where the key markets and assets are. However, in Prof. Hüttermann's view, once Europe is an important market, it is hard to justify ignoring the UPC. He expects the court's caseload and influence to grow strongly over the coming years. A Landmark UPC Case: Syngenta v. Sumitomo A particularly important case in which Prof. Hüttermann was involved is the Syngenta v. Sumitomo matter, concerning a composition patent. This case has become a landmark in UPC practice for several reasons. First, the Court of Appeal clarified a central point about the reach of UPC injunctions. It made clear that once infringement is established in one Member State, this will usually be sufficient to justify a pan-European injunction covering all UPC countries designated by the patent. That confirmation gave patent owners confidence that the UPC can in fact deliver broad, cross-border relief in one go. Second, the facts of the case raised novel issues about evidence and territorial reach. The allegedly infringing product had been analysed based on a sample from the Czech Republic, which is not part of the UPC system. Later, the same product with the same name was marketed in Bulgaria, which is within UPC territory. The Court of Appeal held that the earlier analysis of the Czech sample could be relied on for enforcement in Bulgaria. This showed that evidence from outside the UPC territory can be sufficient, as long as it is properly linked to the products marketed within the UPC. Third, the Court of Appeal took the opportunity to state its view on inventive step. It confirmed that combining prior-art documents requires a “pointer”, in line with the EPO's problem-solution approach. The mere theoretical possibility of extracting a certain piece of information from a document does not suffice to justify an inventive-step attack. This is one of several decisions where the UPC has shown a strong alignment with EPO case law on substantive patentability. For Prof. Hüttermann personally, the case was also a lesson in oral advocacy before the UPC. During the two appeal hearings, the presiding judge asked unexpected questions that required quick and creative responses while the hearing continued. His practical takeaway is that parties should appear with a small, well-coordinated team: large enough to allow someone to work on a tricky question in the background, but small enough to remain agile. Two or three lawyers seem ideal; beyond that, coordination becomes difficult and “too many cooks spoil the broth”. A Game-Changing CJEU Decision: Bosch Siemens Hausgeräte v. Electrolux Surprisingly, one of the most important developments for European patent litigation in the past year did not come from the UPC at all, but from the Court of Justice of the European Union. In Bosch Siemens Hausgeräte v. Electrolux, the CJEU revisited the rules on cross-border jurisdiction under the Brussels I Recast Regulation (Brussels Ia). Previously, under what practitioners often referred to as the GAT/LuK regime, a court in one EU country was largely prevented from granting relief for alleged infringement in another country if the validity of the foreign patent was contested there. This significantly limited the possibilities for cross-border injunctions. In Bosch, the CJEU changed course. Without going into all procedural details, the essence is that courts in the EU now have broader powers to grant cross-border relief when certain conditions are met, particularly when at least one defendant is domiciled in the forum state. The concept of an “anchor defendant” plays a central role: if you sue one group company in its home forum, other group companies in other countries, including outside the EU, can be drawn into the case. This has already had practical consequences. German courts, for example, have issued pan-European injunctions covering around twenty countries in pharmaceutical cases. There are even attempts to sue European companies for infringement of US patents based on acts in the US, using the logic of Bosch as a starting point. How far courts will ultimately go remains to be seen, but the potential is enormous. For the UPC, this development is highly relevant. The UPC operates in the same jurisdictional environment as national courts, and many defendants in UPC cases will be domiciled in UPC countries. This increases the likelihood that the UPC, too, can leverage the broadened possibilities for cross-border relief. In addition, we have already seen UPC decisions that include non-EU countries such as the UK within the scope of injunctions, in certain constellations. The interaction between UPC practice and the Bosch jurisprudence of the CJEU is only beginning to unfold. Does the UPC Follow EPO Case Law? A key concern for many patent owners and practitioners is whether the UPC will follow the EPO's Boards of Appeal or develop its own, possibly divergent, case law on validity. On procedural matters, the UPC is naturally different from the EPO. It has its own rules of procedure, its own timelines and its own tools, such as “front-loaded” pleadings and tight limits on late-filed material. On substantive law, however, Prof. Hüttermann's conclusion is clear: there is “nothing new under the sun”. The UPC's approach to novelty, inventive step and added matter is very close to that of the EPO. The famous “gold standard” for added matter appears frequently in UPC decisions. Intermediate generalisations are treated with the same suspicion as at the EPO. In at least one case, the UPC revoked a patent for added matter even though the EPO had granted it in exactly that form. The alignment is not accidental. The UPC only deals with European patents granted by the EPO; it does not hear cases on purely national patents. If the UPC were more generous than the EPO, many patents would never reach it. If it were systematically stricter, patentees would be more tempted to opt out of the system. In practice, the UPC tends to apply the EPO's standards and, where anything differs, it is usually a matter of factual appreciation rather than a different legal test. For practitioners, this has a very practical implication: if you want to predict how the UPC will decide on validity, the best starting point is to ask how the EPO would analyse the case. The UPC may not always reach the same result in parallel EPO opposition proceedings, but the conceptual framework is largely the same. Trends in UPC Practice: PIs, Equivalents and Division-Specific Styles Even in its early years, certain trends and differences between UPC divisions can be observed. On preliminary injunctions, the local division in Düsseldorf has taken a particularly proactive role. It has been responsible for most of the ex parte PIs granted so far and applies a rather strict notion of urgency, often considering one month after knowledge of the infringement as still acceptable, but treating longer delays with scepticism. Other divisions tend to see two months as still compatible with urgency, and they are much more cautious with ex parte measures. Munich, by contrast, has indicated a strong preference for inter partes PI proceedings and appears reluctant to grant ex parte relief at all. A judge from Munich has even described the main action as the “fast” procedure and the inter partes PI as the “very fast” one, leaving little room for an even faster ex parte track. There are also differences in how divisions handle amendments and auxiliary requests in PI proceedings. Munich has suggested that if a patentee needs to rely on claim amendments or auxiliary requests in a PI, the request is unlikely to succeed. Other divisions have been more open to considering auxiliary requests. The doctrine of equivalents is another area where practice is not yet harmonised. The Hague division has explicitly applied a test taken from Dutch law in at least one case and found infringement by equivalence. However, the Court of Appeal has not yet endorsed a specific test, and in another recent Hague case the same division did not apply that Dutch-law test again. The Mannheim division has openly called for the development of an autonomous, pan-European equivalence test, but has not yet fixed such a test in a concrete decision. This is clearly an area to watch. Interim conferences are commonly used in most divisions to clarify issues early on, but Düsseldorf often dispenses with them to save time. In practice, interim conferences can be very helpful for narrowing down the issues, though parties should not expect to be able to predict the final decision from what is discussed there. Sometimes topics that dominate the interim conference play little or no role in the main oral hearing. A Front-Loaded System and Typical Strategic Mistakes UPC proceedings are highly front-loaded and very fast. A defendant usually has three months from service of the statement of claim to file a full statement of defence and any counterclaim for revocation. This is manageable, but only if the time is used wisely. One common strategic problem is that parties lose time at the beginning and only develop a clear strategy late in the three-month period. According to Prof. Hüttermann, it is crucial to have a firm strategy within the first two or three weeks and then execute it consistently. Constantly changing direction is a recipe for failure in such a compressed system. Another characteristic is the strict attitude towards late-filed material. It is difficult to introduce new documents or new inventive-step attacks later in the procedure. In some cases even alternative combinations of already-filed prior-art documents have been viewed as “new” attacks and rejected as late. At the appeal stage, the Court of Appeal has even considered new arguments based on different parts of a book already in the file as potentially late-filed. This does not mean that parties should flood the court with dozens of alternative attacks in the initial brief. In one revocation action, a plaintiff filed about fifty different inventive-step attacks, only to be told by the court that this was not acceptable and that the attacks had to be reduced and structured. The UPC is not a body conducting ex officio examination. It is entitled to manage the case actively and to ask parties to focus on the most relevant issues. Evidence Gathering, Protective Letters and the Defendant's Perspective The UPC provides powerful tools for both sides. Evidence inspection is becoming more common, not only at trade fairs but also at company premises. This can be a valuable tool for patentees, but it also poses a serious risk for defendants who may suddenly face court-ordered inspections. From the perspective of potential defendants, protective letters are an important instrument, especially in divisions like Düsseldorf where ex parte PIs are possible. A well-written protective letter, filed in advance, can significantly reduce the risk of a surprise injunction. The court fees are moderate, but the content of the protective letter must be carefully prepared; a poor submission can cause more harm than good. Despite the strong tools available to patentees, Prof. Hüttermann does not view the UPC as unfair to defendants. If a defendant files a solid revocation counterclaim, the pressure shifts to the patentee, who then has only two months to reply, prepare all auxiliary requests and adapt the enforcement strategy. This is even more demanding than at the EPO, because the patentee must not only respond to validity attacks but also ensure that any amended claims still capture the allegedly infringing product. It is entirely possible to secure the survival of a patent with an auxiliary request that no longer covers the defendant's product. In that scenario, the patentee has “won” on validity but lost the infringement case. Managing this tension under tight time limits is a key challenge of UPC practice. The Future Role of the UPC and How to Prepare Today the UPC hears a few hundred cases per year, compared with several thousand patent cases in the US and tens of thousands in China. Nevertheless, both the court itself and experienced practitioners see significant growth potential. Prof. Hüttermann expects case numbers to multiply in the medium term. Whether the UPC will become the first choice forum in global disputes or remain one pillar in parallel proceedings alongside the US and China will depend on the strategies of large patentees and the evolution of case law. However, the court is well equipped: it covers a large, economically important territory, is comparatively cost-effective and offers fast procedures with robust remedies. For companies that may end up before the UPC, preparation is essential. On the offensive side, that means building strong evidence and legal arguments before filing, being ready to proceed quickly and structured, and understanding the specific styles of the relevant divisions. On the defensive side, it may mean filing protective letters in risk-exposed markets, preparing internal processes for rapid reaction if a statement of claim arrives, and taking inspection requests seriously. Conclusion The Unified Patent Court has quickly moved from theory to practice. It offers pan-European relief, fast and front-loaded procedures, and a substantive approach that closely mirrors the EPO's case law. At the same time, national and EU-level developments like the Bosch Siemens Hausgeräte v. Electrolux decision are reshaping the jurisdictional framework in which the UPC operates, opening the door for far-reaching cross-border injunctions. For patent owners and potential defendants alike, the message is clear: the UPC is here to stay and will become more important year by year. Those who invest the time to understand its dynamics now – including its alignment with the EPO, the differences between divisions, and the strategic implications of its procedures – will be in a much better position when the first UPC dispute lands on their desk. Here is the full transcript of the interview: Rolf Claessen:Today's interview guest is Prof. Aloys Hüttermann. He is founder and equity partner of my firm, Michalski · Hüttermann & Partner. More importantly for today's interview, he has written several books about the Unified Patent Court. The first one already came out in 2016. He is co-editor and author of one of the leading commentaries on the UPC and has gained substantial experience in UPC cases so far – one of them even together with me. Thank you very much for being on IP Fridays again, Aloys. Aloys Hüttermann:Thank you for inviting me, it's an honour. How did you get so deeply involved in the UPC? Rolf Claessen:Before we dive into the details, how did you end up so deeply involved in the Unified Patent Court? And what personally fascinates you about this court? Aloys Hüttermann:This goes back quite a while – roughly 13 years. At that time it became clear that, after several failed attempts, Europe would really get a pan-European court and a pan-European patent, and that this time it was serious. I thought: this is going to be the future. That interested me a lot, both intellectually and practically. A completely new system was being built. You could watch how it evolved – and, if possible, even help shape it a bit. It was also obvious to me that this would be a complete game changer. Nobody expected that it would take until 2023 before the system actually started operating, but now it is here. I became heavily interested early on. As you mentioned, my first book on the UPC was published in 2016, in the expectation that the system would start soon. It took a bit longer, but now we finally have it. UPC vs. US and China – speed, cost and impact Rolf Claessen:Before we go deeper into the UPC, let's zoom out. If you compare litigation before the UPC with patent litigation in the US and in China – in terms of speed, cost and the impact of decisions – what are the key differences that a business leader should understand? Aloys Hüttermann:If you look at the three big regions – the UPC territory in Europe, the US and China – these are the major economic areas for many technology companies. One important point is territorial reach. In the UPC, if the conditions are met, you can get pan-European injunctions that cover many EU Member States in one go. We will talk about this later in more detail. On costs there is a huge difference between the US and the UPC. The UPC is much cheaper than US litigation, especially once you look at the number of countries you can cover with one case if the patent has been validated widely. China is different again. The number of patent infringement cases there is enormous. I have seen statistics of around 40,000 infringement cases per year in China. That is huge – compared with roughly 164 UPC infringement cases in the first year and maybe around 200 in the current year. On speed, Chinese courts are known to be very fast. You often get a first-instance decision in about a year. The UPC is comparable: if there is a counterclaim for revocation, you are looking at something like 12 to 15 months for a first-instance decision. The US can be slower, and the procedure is very different. You have full discovery, you may have juries. None of that exists at the UPC. From that perspective, Chinese and UPC proceedings are more similar to each other than either is to the US. The UPC is still a young court. We have to see how influential its case law will be worldwide in the long run. What we already see, at least in Germany, is a clear trend away from purely national patent litigation and towards the UPC. That is inside Europe. The global impact will develop over time. When is the UPC the most powerful tool? Rolf Claessen:Let's take the perspective of a global company. It has significant sales in Europe and in the US and production or key suppliers in China. In which situations would you say the UPC is your most powerful tool? And when might the US or China be the more strategic battleground? Aloys Hüttermann:To be honest, I would almost always consider bringing a case before the UPC. The “bang for the buck” is very good. The UPC is rather fast. That alone already gives you leverage in negotiations. The threat of a quick, wide-reaching injunction is a strong negotiation tool. Whether you litigate in the US instead of the UPC, or in addition, or whether you also go to China – that depends heavily on the individual case: where the products are sold, where the key markets are, where the defendant has assets, and so on. But in my view, once you have substantial sales in Europe, you should seriously consider the UPC. And for that reason alone I expect case numbers at the UPC to increase significantly in the coming years. A landmark UPC case: Syngenta vs. Sumitomo (composition patent) Rolf Claessen:You have already been involved in several UPC cases – and one of them together with me, which was great fun. Looking at the last 12 to 18 months, is there a case, decision or development that you find particularly noteworthy – something that really changed how you think about UPC litigation or how companies should prepare? Aloys Hüttermann:The most important UPC case I have been involved in so far is the Syngenta v. Sumitomo case on a composition patent. It has become a real landmark and was even mentioned in the UPC's annual report. It is important for several reasons. First, it was one of the first cases in which the Court of Appeal said very clearly: if you have established infringement in one Member State, that will usually be enough for a pan-European injunction covering all UPC countries designated by the patent. That is a powerful statement about the reach of UPC relief. Second, the facts were interesting. The patent concerned a composition. We had analysed a sample that had been obtained in the Czech Republic, which is not a UPC country. Later, the same product was marketed under the same name in Bulgaria, which is in the UPC. The question was whether the analysis of the Czech sample could be used as a basis for enforcement in Bulgaria. The Court of Appeal said yes, that was sufficient. Third, the Court of Appeal took the opportunity to say something about inventive step. It more or less confirmed that the UPC's approach is very close to the EPO's problem-solution approach. It emphasised that, if you want to combine prior-art documents, you need a “pointer” to do so. The mere theoretical possibility that a skilled person could dig a particular piece of information out of a document is not enough. For me personally, the most memorable aspect of this case was not the outcome – that was largely in line with what we had expected – but the oral hearings at the appeal stage. We had two hearings. In both, the presiding judge asked us a question that we had not anticipated at all. And then you have about 20 minutes to come up with a convincing answer while the hearing continues. We managed it, but it made me think a lot about how you should prepare for oral hearings at the UPC. My conclusion is: you should go in with a team, but not too big. In German we say, “Zu viele Köche verderben den Brei” – too many cooks spoil the broth. Two or three people seems ideal. One of them can work quietly on such a surprise question at the side, while the others continue arguing the case. In the end the case went very well for us, so I can speak about it quite calmly now. But in the moment your heart rate definitely goes up. The CJEU's Bosch Siemens Hausgeräte v. Electrolux decision – a real game changer Rolf Claessen:You also mentioned another development that is not even a UPC case, but still very important for European patent litigation. Aloys Hüttermann:Yes. In my view, the most important case of the last twelve months is not a UPC decision but a judgment of the Court of Justice of the EU (CJEU): Bosch Siemens Hausgeräte v. Electrolux. This is going to be a real game changer for European IP law, and I am sure we have not seen the end of its effects yet. One example: someone has recently sued BMW before the Landgericht München I, a German court, for infringement of a US patent based on acts in the US. The argument is that this could be backed by the logic of Bosch Siemens Hausgeräte v. Electrolux. We do not know yet what the court will do with that, but the fact that people are trying this shows how far-reaching the decision might be. Within the UPC we have already seen injunctions being issued for countries outside the UPC territory and even outside the EU, for example including the UK. So you see how these developments start to interact. Rolf Claessen:For listeners who have not followed the case so closely: in very simple terms, the CJEU opened the door for courts in one EU country to rule on patent infringement that took place in other countries as well, right? Aloys Hüttermann:Exactly. Before Bosch Siemens Hausgeräte v. Electrolux we had what was often called the GAT/LuK regime. The basic idea was: if you sue someone in, say, Germany for infringement of a European patent, and you also ask for an injunction for France, and the defendant then challenges the validity of the patent in France, the German court cannot grant you an injunction covering France. The Bosch decision changed that. The legal basis is the Brussels I Recast Regulation (Brussels Ia), which deals with jurisdiction in civil and commercial matters in the EU. It is not specific to IP; it applies to civil cases generally, but it does have some provisions that are relevant for patents. In Bosch, a Swedish court asked the CJEU for guidance on cross-border injunctions. The CJEU more or less overturned its old GAT/LuK case law. Now, in principle, if the defendant is domiciled in a particular Member State, the courts of that state can also grant cross-border relief for other countries, under certain conditions. We will not go into all the details here – that could fill a whole separate IP Fridays episode – but one important concept is the “anchor defendant”. If you sue a group of companies and at least one defendant is domiciled in the forum state, then other group companies in other countries – even outside the EU, for example in Hong Kong – can be drawn into the case and affected by the decision. This is not limited to the UPC, but of course it is highly relevant for UPC litigation. Statistically it increases the chances that at least one defendant will be domiciled in a UPC country, simply because there are many of them. And we have already seen courts like the Landgericht München I grant pan-European injunctions for around 20 countries in a pharmaceutical case. Rolf Claessen:Just to clarify: does it have to be the headquarters of the defendant in that country, or is any registered office enough? Aloys Hüttermann:That is one of the open points. If the headquarters are in Europe, then it is clear that subsidiaries outside Europe can be affected as well. If the group's headquarters are outside Europe and only a subsidiary is here, the situation is less clear and we will have to see what the courts make of it. Does the UPC follow EPO case law? Rolf Claessen:Many patent owners and in-house counsel wonder: does the UPC largely follow the case law of the EPO Boards of Appeal, or is it starting to develop its own distinct line? What is your impression so far – both on substantive issues like novelty and inventive step, and on procedural questions? Aloys Hüttermann:On procedure the UPC is, of course, very different. It has its own procedural rules and they are not the same as at the EPO. If we look at patent validity, however, my impression is that there is “nothing new under the sun” – that was the title of a recent talk I gave and will give again in Hamburg. Substantively, the case law of the UPC and the EPO is very similar. For inventive step, people sometimes say the UPC does not use the classical problem-solution approach but a more “holistic” approach – whatever that is supposed to mean. In practice, in both systems you read and interpret prior-art documents and decide what they really disclose. In my view, the “error bar” that comes from two courts simply reading a document slightly differently is much larger than any systematic difference in legal approach. If you look at other grounds, such as novelty and added matter, the UPC even follows the EPO almost verbatim. The famous “gold standard” for added matter appears all over UPC decisions, even if the EPO case numbers are not always cited. The same is true for novelty. So the rule-based, almost “Hilbertian” EPO approach is very much present at the UPC. There is also a structural reason for that. All patents that the UPC currently deals with have been granted by the EPO. The UPC does not handle patents granted only by national offices. If the UPC wanted to deviate from EPO case law and be more generous, then many patents would never reach the UPC in the first place. The most generous approach you can have is the one used by the granting authority – the EPO. So if the UPC wants to be different, it can only be stricter, not more lenient. And there is little incentive to be systematically stricter, because that would reduce the number of patents that are attractive to enforce before the UPC. Patent owners might simply opt out. Rolf Claessen:We also talked about added matter and a recent case where the Court of Appeal was even stricter than the EPO. That probably gives US patent practitioners a massive headache. They already struggle with added-matter rules in Europe, and now the UPC might be even tougher. Aloys Hüttermann:Yes, especially on added matter. I once spoke with a US practitioner who said, “We hope the UPC will move away from intermediate generalisations.” There is no chance of that. We already have cases where the Court of Appeal confirmed that intermediate generalisations are not allowed, in full alignment with the EPO. You mentioned a recent case where a patent was revoked for added matter, even though it had been granted by the EPO in exactly that form. This shows quite nicely what to expect. If you want to predict how the UPC will handle a revocation action, the best starting point is to ask: “What would the EPO do?” Of course, there will still be cases where the UPC finds an invention to be inventive while the EPO, in parallel opposition proceedings, does not – or vice versa. But those are differences in the appreciation of the facts and the prior art, which you will always have. The underlying legal approach is essentially the same. Rolf Claessen:So you do not see a real example yet where the UPC has taken a totally different route from the EPO on validity? Aloys Hüttermann:No, not really. If I had to estimate how the UPC will decide, I would always start from what I think the EPO would have done. Trends in UPC practice: PIs, equivalents, interim conferences Rolf Claessen:If you look across the different UPC divisions and cases: what trends do you see in practice? For example regarding timelines, preliminary injunctions, how validity attacks are handled, and how UPC cases interact with EPO oppositions or national proceedings? Aloys Hüttermann:If you take the most active divisions – essentially the big four in Germany and the local division in The Hague – they all try to be very careful and diligent in their decisions. But you can already see some differences in practice. For preliminary injunctions there is a clear distinction between the local division in Düsseldorf and most other divisions. Düsseldorf considers one month after knowledge of the infringement as still sufficiently urgent. If you wait longer, it is usually considered too late. In many other divisions, two months is still viewed as fine. Düsseldorf has also been the division that issued most of the ex parte preliminary injunctions so far. Apart from one special outlier where a standing judge from Brussels was temporarily sitting in Milan, Düsseldorf is basically the only one. Other divisions have been much more reluctant. At a conference, Judge Pichlmaier from the Munich division once said that he could hardly imagine a situation where his division would grant an ex parte PI. In his words, the UPC has two types of procedure: one that is fast – the normal main action – and one that is very fast – the inter partes PI procedure. But you do not really have an “ultra-fast” ex parte track, at least not in his division. Another difference relates to amendments and auxiliary requests in PI proceedings. In one recent case in Munich the court said more or less that if you have to amend your patent or rely on auxiliary requests in a PI, you lose. Other divisions have been more flexible and have allowed auxiliary requests. Equivalence is another area where we do not have a unified line yet. So far, only the Hague division has clearly found infringement under the doctrine of equivalents and explicitly used a test taken from Dutch law. Whether that test will be approved by the Court of Appeal is completely open – the first case settled, so the Court of Appeal never ruled on it, and a second one is still very recent. Interestingly, there was another Hague decision a few weeks ago where equivalence was on the table, but the division did not apply that Dutch-law test. We do not know yet why. The Mannheim division has written in one decision that it would be desirable to develop an autonomous pan-European test for equivalence, instead of just importing the German, UK or Dutch criteria. But they did not formulate such a test in that case because it was not necessary for the decision. So we will have to see how that evolves. On timelines, one practical difference is that Düsseldorf usually does not hold an interim conference. That saves them some time. Most other divisions do hold interim conferences. Personally, I like the idea because it can help clarify issues. But you cannot safely read the final outcome from these conferences. I have also seen cases where questions raised at the interim conference did not play any role in the main oral hearing. So they are useful for clarification, but not as a crystal ball. Front-loaded proceedings and typical strategic mistakes Rolf Claessen:If you look at the behaviour of parties so far – both patentees and defendants – what are the most common strategic mistakes you see in UPC litigation? And what would a well-prepared company do differently before the first statement of claim is ever filed? Aloys Hüttermann:You know you do not really want me to answer that question… Rolf Claessen:I do! Aloys Hüttermann:All right. The biggest mistake, of course, is that they do not hire me. That is the main problem. Seriously, it is difficult to judge parties' behaviour from the outside. You rarely know the full picture. There may be national proceedings, licensing discussions, settlement talks, and so on in the background. That can limit what a party can do at the UPC. So instead of criticising, I prefer to say what is a good idea at the UPC. The system is very front-loaded and very fast. If you are sued, you have three months to file your statement of defence and your counterclaim for revocation. In my view, three months are manageable – but only if you use the time wisely and do not waste it on things that are not essential. If you receive a statement of claim, you have to act immediately. You should have a clear strategy within maybe two or three weeks and then implement it. If you change your strategy every few weeks, chances are high that you will fail. Another point is that everything is front-loaded. It is very hard to introduce new documents or new attacks later. Some divisions have been a bit generous in individual cases, but the general line is strict. We have seen, for example, that even if you filed a book in first instance, you may not be allowed to rely on a different chapter from the same book for a new inventive-step attack at the appeal stage. That can be regarded as late-filed, because you could have done it earlier. There is also case law saying that if you first argue inventive step as “D1 plus D2”, and later want to argue “D2 plus D1”, that can already be considered a new, late attack. On the other hand, we had a revocation action where the plaintiff filed about 50 different inventive-step attacks in the initial brief. The division then said: this does not work. Please cut them down or put them in a clear hierarchy. In the end, not all of them were considered. The UPC does not conduct an ex officio examination. It is entitled to manage the case and to tell the parties to limit themselves in the interest of a fair and efficient procedure. Rolf Claessen:I have the feeling that the EPO is also becoming more front-loaded – if you want to rely on documents later, you should file them early. But it sounds like the UPC is even more extreme in that regard. Aloys Hüttermann:Yes, that is true. Protective letters, inspections and the defendant's perspective Rolf Claessen:Suppose someone from a company is listening now and thinks: “We might be exposed at the UPC,” or, “We should maybe use the UPC offensively against competitors.” What would you consider sensible first steps before any concrete dispute arises? And looking three to five years ahead, how central do you expect the UPC to become in global patent litigation compared to the US and China? Aloys Hüttermann:Let me start with the second part. I expect the UPC to become significantly more important. If we have around 200 cases this year, that is a good start, but it is still very small compared to, say, 4,000 to 5,000 patent cases per year in the US and 40,000 or so in China. Even François Bürgin and Klaus Grabinski, in interviews, have said that they are happy with the case load, but the potential is much larger. In my view, it is almost inevitable that we will see four or five times as many UPC cases in the not-too-distant future. As numbers grow, the influence of the UPC will grow as well. Whether, in five or ten years, companies will treat the UPC as their first choice forum – or whether they will usually run it in parallel with US litigation in major disputes – remains to be seen. The UPC would be well equipped for that: the territory it covers is large, Europe is still an important economy, and the UPC procedure is very attractive from a company's perspective. On sensible first steps: if you are worried about being sued, a protective letter can make a lot of sense – especially in divisions like Düsseldorf, where ex parte PIs are possible in principle. A protective letter is not very expensive in terms of court fees. There is also an internal system that ensures the court reads it before deciding on urgent measures. Of course, the content must have a certain quality; a poor protective letter can even backfire. If you are planning to sue someone before the UPC, you should be extremely well prepared when you file. You should already have all important documents and evidence at hand. As we discussed, it is hard to introduce new material later. One tool that is becoming more and more popular is inspection – not just at trade fairs, where we already saw cases very early, but also at company premises. Our firm has already handled such an inspection case. That is something you should keep in mind on both sides: it is a powerful evidence-gathering tool, but also a serious risk if you are on the receiving end. From the defendant's perspective, I do not think the UPC is unfair. If you do your job properly and put a solid revocation counterclaim on the table, then the patentee has only two months to prepare a full reply and all auxiliary requests. And there is a twist that makes life even harder for the patentee than at the EPO. At the EPO the question is mainly: do my auxiliary requests overcome the objections and are they patentable? At the UPC there is an additional layer: do I still have infringement under the amended claims? You may save your patent with an auxiliary request that no longer reads on the defendant's product. That is great for validity, but you have just lost the infringement case. You have kept the patent but lost the battle. And all of this under very tight time limits. That creates considerable pressure on both sides. How to contact Prof. Hüttermann Rolf Claessen:Thank you very much for this really great interview, Aloys. Inside our firm you have a nickname: “the walking encyclopedia of the Unified Patent Court” – because you have written so many books about it and have dealt with the UPC for such a long time. What is the best way for listeners to get in touch with you? Aloys Hüttermann:The easiest way is by email. You can simply write to me, and that is usually the best way to contact me. As you may have noticed, I also like to speak. I am a frequent speaker at conferences. If you happen to be at one of the conferences where I am on the programme – for example, next week in Hamburg – feel free to come up to me and ask me anything in person. But email is probably the most reliable first step. Rolf Claessen:Perfect. Thank you very much, Aloys. Aloys Hüttermann:Thank you. It was a pleasure to be on IP Fridays again. Some of your long-time listeners may remember that a few years ago – when you were not yet part of our firm – we already did an episode on the UPC, back when everything was still very speculative. It is great to be back now that the system is actually in place and working. Rolf Claessen:I am very happy to have you back on the show.
Join hosts Adam Hall and Walt Cerrato as they sit down with Brett Larrick, Head Boys Basketball Coach at Elyria High School.The Holding Court Podcast is presented by the Ohio High School Basketball Coaches Association.This podcast is available anywhere you listen to podcasts. Make sure to subscribe. Also, check us out here:linktr.ee/OHSBCAThis episode is powered by Fundraising University (Ohio). If you are looking to raise money for your program, Fundraising University (Ohio) is the way to go! For more information, visit https://fundraisingu.net/.
Is South Africa about to collapse? Nick interviews South African entrepreneur Rob Hersov to discuss the situation in South Africa and what can be done to turn things around.SPONSOR: Good Ranchers Serve only the best meat for the holidays! Over 85% of grass-fed beef sold in U.S. stores is imported, but Good Ranchers offers 100% American-sourced meat, supporting local farms. We eat Good Ranchers every single day and we know you'll love it.Order by December 1st and use code NICK to get an extra $100 off your first three orders + FREE MEAT: https://go.goodranchers.com/nickfreitas-----SPONSOR: Lear CapitalThe best way to invest in gold and silver is with Lear Capital. Get your FREE Gold and Silver investor guides from Lear Capital. And, receive up to $15,000 in FREE bonus metals with a qualified purchase.Call them today at 800-707-4575 or go to: Nick4Lear.com-----Support the show and surprise your friends and family with MTA gear for Christmas! Grab something awesome from our online shop. We've got T-shirts, mugs, and more - all designed for fans like you.GET YOUR MERCH HERE: https://shop.nickjfreitas.com/BECOME A MEMBER OF THE IC: https://NickJFreitas.comInstagram: www.instagram.com/nickjfreitas/Facebook: https://www.facebook.com/NickFreitasVATwitter: https://twitter.com/NickJFreitasYouTube: https://www.youtube.com/@NickjfreitasTikTok: https://www.tiktok.com/@nickfreitas3.000:00:00 Intro00:01:41 Why South Africa is So Important to the World00:05:49 Is South Africa Now a Failed State?00:13:20 The Current State of South African Democracy00:16:14 How the ANC Captured Control of South Africa00:21:24 When Did Things Begin to Fall Apart?00:26:15 Corruption and Socialism00:29:57 South Africa is Splintering by Region and Party00:43:08 Why Continue to Live in South Africa?00:49:00 The ANC's Grip on Power is Declining00:54:20 Is it Possible to Turn Things Around?01:02:10 Where People Can Find More About Rob
Can we reduce OR waste without compromising patient care? In this episode of BackTable Urology, Dr. Sunil Patel (Johns Hopkins) joins host Dr. Ruchika Talwar (Vanderbilt) to explore strategies for improving environmental sustainability in surgical practice. --- SYNPOSIS They discuss the scope of OR-generated waste, the impact of plastics and carbon emissions, and emerging data linking environmental exposures to carcinogenesis. Dr. Patel highlights evidence supporting reusable vs. single-use instruments, shares examples of successful waste-reduction initiatives, and emphasizes the importance of cross-disciplinary collaboration to make sustainable practices achievable across healthcare systems. --- TIMESTAMPS 0:00 - Introduction3:29 - Current State of OR Waste20:09 - Strategies to Reduce Waste24:52 - Impact of Climate Change on Patients33:55 - Future Directions40:27 - Conclusion
Santiago Roel Santos is the founder and CEO of Inversion a crypto-native holding company that acquires and transforms traditional businesses using blockchain technology. He is among the most active investors in crypto, having backed over 150 startups and many industry leaders over the past decade. Previously, Santiago was a Partner at ParaFi Capital, an institutional blockchain investor managing over $1 billion. He also held investment roles at Sageview Capital, a $2 billion growth equity firm focused on software and tech-enabled businesses, and at JP Morgan's Investment Banking Financial Sponsors Group. In this conversation, we discuss:- Santiago's recent substack post - You don't value casino flow like recurring software revenue - Infrastructure vs application value - Crypto's valuation problem - Why most blockchains today are overvalued and how value will flow to the businesses built on crypto rails - Mental models - Systemic friction is a huge business opp - Techno-optimism is at an all-time high - Prediction markets are a better version of the media Inversion X: @inversion_capWebsite: inversioncap.comLinkedIn: InversionSantiago Roel SantosX: @santiagoroelLinkedIn: Santiago R.---------------------------------------------------------------------------------This episode is brought to you by PrimeXBT.PrimeXBT offers a robust trading system for both beginners and professional traders that demand highly reliable market data and performance. Traders of all experience levels can easily design and customize layouts and widgets to best fit their trading style. PrimeXBT is always offering innovative products and professional trading conditions to all customers. PrimeXBT is running an exclusive promotion for listeners of the podcast. After making your first deposit, 50% of that first deposit will be credited to your account as a bonus that can be used as additional collateral to open positions. Code: CRYPTONEWS50 This promotion is available for a month after activation. Click the link below: PrimeXBT x CRYPTONEWS50FollowApple PodcastsSpotifyAmazon MusicRSS FeedSee AllFollowApple PodcastsSpotifyAmazon Music
Episode Deep-Dive Analysis Available at maffeodrinks.com Maurice Doyle returns to MAFFEO DRINKS to dissect the drinks industry's inflection point, where COVID's artificial peak has given way to a "new reality" of capital constraints and complexity.Drawing from his veteran experience across major spirits and scale-up companies, Maurice reveals how brands can achieve growth without abundant funding by focusing ruthlessly on strategy, particularly what NOT to do.The conversation explores the tension between principles and tactics, why "I don't know" might be the most powerful leadership phrase, and how misaligned expectations between bottom-up brand building and top-down objectives create systemic friction.Maurice's core insight: in a world where 95% of your target market isn't buying at any given moment, success comes from matching physical availability with mental availability while resisting the siren call of premature retail listings.Timestamps:00:00 Introduction and Industry Veterans Discussion02:30 Current State of Drinks Industry - The Inflection Point08:15 Capital Challenges and New Reality Post-COVID12:45 Strategic Focus: The Power of Saying No18:20 Principles vs Playbooks - Beyond Cookie Cutter Approaches25:10 Getting Out From Behind the Desk Philosophy32:40 Capital-Efficient Growth Strategies38:55 Balancing Long-term Strategy with Short-term Pressures If what we discussed hits home and you want support from us, get in touch at bottomup@maffeodrinks.com or check maffeodrinks.com for the key insights from this episode.
My podcast won two awards this year - but not for the reasons you might think. This episode unpacks the creative decisions, format choices, and editorial discipline that made EDIT HISTORY resonate with judges and listeners alike. Whether you're building a podcast, a business, or any long-term creative project, this is a deep dive into what really matters. TIMETAMPS (00:00) Introduction (03:31) The Current State of Podcasts (05:12) Show Concept (09:29) Differentiation (15:14) Consistency (18:23) Success as a Podcaster (20:30) What Awards Don't Measure CONNECT WITH CHERYL LAU Website: https://cheryllau.com YouTube: https://www.youtube.com/@cheryltheory Instagram: https://www.instagram.com/cheryltheory LinkedIn: https://www.linkedin.com/in/cheryllau WORK WITH CHERYL LAU I help business leaders, creators, and organizations create a body of work they're proud of - One that's substantial, distinct, and built to last. Think of me as your strategic podcast partner - someone who's as invested in your vision as you are. I care about making sure your content actually stands out, resonates, and opens the right doors. Here are two ways we can work together: ✨ 1:1 Editorial Podcast Production -A done-for-you podcast experience for business owners, consultants, and creators who want a distinctive, intelligent show that elevates their voice and attracts aligned opportunities. I specialize in educational and thought-leadership podcasts - guiding you from concept to production and launch. ✨ Corporate Podcast Producing & Consulting - For organizations ready to build high-quality, strategically positioned podcasts. From concept development to scripting and host coaching, I direct capstone content projects with clarity and care. I specialize in educational and thought-leadership podcasts - guiding you from concept to production and launch. Schedule a discovery call for us to explore what working together might look like: https://cheryllau.com/discovery CONTACT Please email hello@cheryllau.com for business inquiries.
My guest today is Cosmo Jiang, Partner at Pantera Capital. Pantera was one of the earliest institutional voices to embrace digital asset treasury companies, or DATs, and helped catalyze the Solana DAT wave. We begin by unpacking the DAT investment thesis using a traditional fundamental investing framework. We then discuss the role of DATs in the crypto-ecosystem, the convergence of crypto and traditional finance, and why Solana is their largest position. Please enjoy this conversation with Cosmo Jiang. For the full show notes, transcript, and links to the best content to learn more, check out the episode page HERE. ----- Making Markets is a property of Colossus, LLC. For more episodes of Making Markets, visit joincolossus.com/episodes. Stay up to date on all our podcasts by signing up to Colossus Weekly, our quick dive every Sunday highlighting the top business and investing concepts from our podcasts and the best of what we read that week. Sign up here. Follow us on Twitter: @makingmkts | @ericgoldenx Editing and post-production work for this episode was provided by The Podcast Consultant (https://thepodcastconsultant.com). Show Notes (00:00:00) Welcome to Making Markets (00:01:04) Introduction to Digital Asset Treasury Companies (DATs) (00:01:44) Understanding the Role of DATs in the Crypto Ecosystem (00:02:48) The Investment Thesis Behind DATs (00:04:13) Comparing DATs to Traditional Financial Models (00:06:59) MicroStrategy's Strategy and Performance (00:09:53) Active Management vs. Passive Investment in DATs (00:13:40) Pantera Capital's Journey with DATs (00:16:51) The Rise of Solana DATs (00:20:20) Advocating for Solana and the Role of Spokespersons (00:22:46) Guiding Investors on Solana Exposure (00:23:28) Exploring AI Investment Strategies (00:24:10) The Role of ETFs in Digital Asset Management (00:25:19) Active Management vs. Spot Investments (00:25:53) The Future of Digital Asset Treasuries (00:27:43) The Intersection of TradFi and Crypto (00:29:24) Governance and Decentralization in Crypto (00:33:22) Solana: A Promising Layer 1 Blockchain (00:43:21) Current State and Future of Crypto Markets Learn more about your ad choices. Visit megaphone.fm/adchoices
In this episode of The P.A.S. Report Podcast, Nick Giordano speaks with Gloria Giorno, founder of the Reagan Society and author of Outcast: How the Radical Left Tried to Destroy a Young Conservative, to expose the growing challenges facing young conservatives in America. From the indoctrination embedded in modern education to the dangerous influence of socialism, AI, and social media, Gloria details her own experiences with political targeting and explains why the cultural environment is more hostile than ever. Together, they break down how the cultural rot, why conservatives have grown complacent, and what must be done to restore civic engagement, teach history accurately, and protect the freedoms that define America. Episode Highlights How indoctrination and AI threaten education, critical thinking, and future generations Gloria's personal stories of political targeting and what they reveal about modern America Why conservative unity, civic engagement, and active voting are essential for preserving freedom
AI is no longer a buzzword, it is quietly reshaping how companies work, hire, and compete. In this episode, I sit down with AI and automation expert (and repeat founder) Luke Thompson to unpack the real state of AI and what it means for business leaders. We talk about why free AI tools give you a false sense of security, why executives must lean in instead of banning AI, and how to build simple automations that tame your inbox and free up real time. Luke breaks down digital twins, MCP, agent workflows, and security risks in plain English, with practical examples you can apply this week. If you are a CEO, founder, or executive trying to decide what to do next with AI, this conversation is your roadmap. ----- Frustrated with your government contracting journey? Join our group coaching community here: federal-access.com/gamechangers Grab my #1 bestselling book, "I'm New to Government Contracting. Where Should I Start?" Here: https://amzn.to/4hHLPeE Book a call with me here: https://calendly.com/michaellejeune/govconstrategysession
This is a recurring podcast focused on the latest things happening in climbing and what it means for our sport from industry veterans: Carlo Traversi, Will Anglin, Austin Hoyt, and Joshua Horsley.Look at the Chapters for today's topics.Patreon Questions (join Patreon for extended cut with answers):All things shoes! Stiff shoes or soft shoes? Should you have a special pair for sending and a different pair for training? And more…What does and does not factor into a grade? Approach? Morphology? Risk? Condition? And how FA's decide to grade based on these factors.Join Patreon: HERE Follow us on Instagram: HERE Visit our podcast page: HERE
Today we are diving into the questions every small product business is asking in mid November. Am I ready for Black Friday. Is it too late to plan. What should I focus on if I do not have much time. How do I reengage a quiet list. How do I stand out in a crowded inbox. And once the weekend is over, how do I turn those new customers into repeat buyers. This episode is packed with practical, commercial advice to help you stay focused and profitable during the busiest season of the year. I am joined by Sarah Mathias, founder of This Is Growth. I have long admired Sarah's straight talking business advice and I am so excited to bring her to the podcast. Sarah helps product brands become more profitable and more memorable through smart, commercial marketing that brings the whole picture together. She blends brand, email, content, ads and conversion strategy in a way that feels clearer, more strategic and more doable for small product businesses. If you have been feeling behind, overwhelmed or unsure where to put your energy, this episode will help you get focused fast. Timestamps 00:00 Introduction and Black Friday Readiness 01:01 Meet Sarah Mathias: E-commerce Expert 02:29 Current State of Black Friday Preparations 04:19 Effective Last-Minute Strategies 07:12 The Power of Email Marketing 09:33 Consumer Behavior and Email Frequency 17:36 Alternative Black Friday Strategies 19:21 Value-Based Campaigns and Brand Perception 27:29 Big Brands vs. Small Businesses 30:07 The Genius of Brand Recruitment 31:13 Navigating Black Friday Dilemmas 33:26 Effective Email Marketing Strategies 37:39 Post-Black Friday Customer Retention 46:13 Planning and Organizing for Success 51:28 Final Thoughts and Workshop Invitation In this episode we cover What to do if you feel behind What is still possible in mid November and what is not worth your time. Where to focus when time is short Why email is the fastest way to generate revenue and how to use segmentation to warm up your best buyers. How to reengage a quiet email list Who to email first, what to send, and why no one is judging you for going quiet. How often you can email during Black Friday Why most small brands send far too few emails, and why unsubscribes are not the problem people think they are. What to do if you cannot offer a big discount Alternative strategies that still convert, including bundles, gifts with purchase and value based messaging. How to write subject lines that stand out Why your subject line needs to be clear, bold and unmissable during Black Friday week. How to turn new customers into repeat buyers Why Q1 is critical for retention and the simple offers that bring customers back quickly. Short term planning for December Why gifting, last shipping dates and customer expectations matter more than you think. What brands who are thriving right now have in common Planning, simple strategy and a trading calendar that keeps everything moving. If you only do one thing this week Email your list. Email outperforms social at every turn in Q4 and most small brands are not emailing nearly enough. Links mentioned Small Business Collaborative Website: https://www.smallbusinesscollaborative.co.uk/ Instagram: https://www.instagram.com/small_business_collaborative/ Sarah Mathias, This Is Growth Instagram: https://www.instagram.com/thisisgrowthecom/ Website: https://www.thisisgrowth.co.uk/ Free Workshop: From One Time to Lifetime If you are listening in real time, Sarah and I are hosting a free workshop together this week. From One Time to Lifetime: How to turn your seasonal customers into returning customers Date: Thursday 20 November Time: 12 pm UK time Register free: https://smallbusinesscollaborative.myflodesk.com/retention You will learn: • How to identify your highest value customers • How to bring Q4 customers back quickly in Q1 • The key retention levers that work for small product brands • A simple plan you can follow for the next three months Come live if you can. It will be a practical, high value session. If you enjoyed this episode Share a screenshot while you listen. If you are packing orders or making products, tag both of us on Instagram so we can cheer you on. Thank you for listening to Let's Talk Shop.
11.13.25 Hour 2, University of Maryland Sports reporter Jeff Ermann joins The Kevin Sheehan Show to discuss the state of Terps football with Mike Locksley and how the Men's Basketball team has started with new coach Buzz Williams. Paul Charchian from Fantasy Football Weekly joins The Kevin Sheehan Show to give his weekly fantasy football analysis and projections for the NFL season.
11.13.25, University of Maryland Sports reporter Jeff Ermann joins The Kevin Sheehan Show to discuss the state of Terps football with Mike Locksley and how the Men's Basketball team has started with new coach Buzz Williams.
No Priors: Artificial Intelligence | Machine Learning | Technology | Startups
Bringing new drugs to market is a costly, time-consuming endeavor. On top of that, most medicines fail at some point in the research and development phase. Sarah Guo is joined by Sajith Wickramasekara, co-founder and CEO of Benchling, a company that has not only become the central system of record for biotech R&D, but uses AI agents to assist scientists to help fix this broken system. Sajith details the roadblocks that impede drug development and approval, the “dot com” bust occurring in biotech, and how AI agents and simulation can help scientists experiment faster. Plus, they talk about China's competitive rise in the pharma space, and the unique challenges of building an interdisciplinary culture that merges the worlds of science and software. Rebuild biotech for the AI era - Sajith Wickramasekara Sign up for new podcasts every week. Email feedback to show@no-priors.com Follow us on Twitter: @NoPriorsPod | @Saranormous | @EladGil | @sajithw | @benchling Chapters: 00:00 – Sajith Wickramasekara Introduction 00:38 – Origin and Mission of Benchling 02:08 – The Drug Development Process 03:49 – Current State of the Biotech industry 08:46 – AI's Role in Biotech 16:14 – Benchling AI and Its Impact 18:36 – The Future of AI in Biotech 26:28 – Debunking AI Drug Discovery Myths 28:50 – Data's Role in Biotech 29:35 – The Importance of Tools in Pharma 31:28 – AI's Impact on Scientific Research 34:55 – Building a Biotech Company 40:18 – Interdisciplinary Collaboration in Biotech 43:06 – Tech and Biotech: Learning from Each Other 48:16 – Conclusion
From time to time, we'll re-air a previous episode of the show that our newer audience may have missed. During this episode, Santosh is joined by Chris Jamroz, CEO of Roadrunner Freight. In this conversation, Santosh and Chris explore the transformative impact of technology and innovative business models in the less-than-truckload (LTL) freight sector. Chris shares his journey from investment banking to logistics, detailing Roadrunner's significant turnaround. The discussion covers the complexities of the LTL market, the importance of disciplined pricing, and the role of technology in modernizing the industry. Chris emphasizes the need for automation and digitization to enhance efficiency and reduce manual tasks, highlighting the sector's potential for growth and improvement. Don't miss this great conversation. Highlights from their conversation include:Chris's Background and Journey to Roadrunner (1:18)Roadrunner's Comeback Story (2:39)Vision for Roadrunner's Future (4:50)Management Frameworks (6:15)Understanding LTL (9:33)Types of Freight for LTL (12:46)LTL Pricing Complexity (15:02)Carrier Pricing Philosophy (18:13)Current State of the LTL Market (21:34)Freight Brokers and LTL (23:58)Investment in Technology (26:31)Impact of US Elections on Supply Chains (28:40)Overused Business Buzzwords (29:02)Final Thoughts and Takeaways (29:32)Dynamo is a VC firm led by supply chain and mobility specialists that focus on seed-stage, enterprise startups.Find out more at: https://www.dynamo.vc/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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11.4.25, Kevin Sheehan asks callers for their thoughts on the current state of the Commanders sitting at a 3-6 record and the star quarterback injured.
Join Mike and Pam today as we answer your listener questions! Today we discuss thoughts on the current state of entertainment around Disney's Boardwalk as we answer a question about how best to get home to French Quarter from a late-night at Atlantic Dance Hall! We also get a great question about spectating for the Walt Disney World Marathon and using the runDisney buses, (plus best signs we have seen on the course!), talk about tips for 4th of July and staying at Disney's Yacht Club Resort and much more! Come join the BOGP Clubhouse on our Discord channel at www.beourguestpodcast.com/clubhouse! Thank you so much for your support of our podcast! Become a Patron of the show at www.Patreon.com/BeOurGuestPodcast. Also, please follow the show on Twitter @BeOurGuestMike and on Facebook at www.facebook.com/beourguestpodcast. Thanks to our friends at The Magic For Less Travel for sponsoring today's podcast!