Podcasts about Amylase

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In this episode of The Dairy Nutrition Blackbelt Podcast, Dr. Lucas Rebelo from Adisseo shares key research on how corn with high alpha-amylase expression affects dairy cattle nutrition. He discusses the trial results, highlighting improvements in dry matter intake, increased milk production, and the nuanced impacts on microbial protein synthesis. Tune in now on all major platforms!"We found that the energy in corn silage treatment increased dry matter intake by about 1.6 kilos and milk yield by about 3.4 kilos."Meet the guest: Dr. Lucas Rocha Rebelo is a Dairy Technical Manager at Adisseo with a strong background in dairy nutrition and environmental science. He earned his Ph.D. from The Ohio State University, where he researched amino acid metabolism in dairy cows. Dr. Rebelo also holds an M.Sc. in Ruminant Nutrition from Universidade Estadual Paulista and a B.Sc. in Animal Science from the Federal University of Mato Grosso.What will you learn: (00:00) Highlight(01:04) Introduction(01:31) Corn silage trial(02:37) Treatment comparisons(03:49) Production responses(05:13) Grain processing issues(06:20) Microbial protein(08:47) Closing thoughtsThe Dairy Nutrition Blackbelt Podcast is trusted and supported by the innovative companies:* Adisseo- Evonik- Volac- Virtus Nutrition

Blessings babes! We are so excited to be coming to y'all with a new series!!! EYYY! Sacred sugars is topic we've been longing to share as many people have a strained relationship with “sugar” in our lives/diet/etc. This series is here to empower you and all about seeing the sacred in all things sugar and sweet! As always, we want to thank you for all of your support, in all the ways! we're trying to build up this patreon, so that we can sustainably fund the work we already do with the podcast. so if you're not yet a patreon, join today @ ⁠patreon.com/pettyherbalist⁠. Sources and what's In the episode: Womanism (book) Botanical Medicine for Women's Health by Aviva Romm (book) Eve by Cat Bohannon (herb) Mullein - Verbascum Thapsus (podcast) A Little Juju Podcast (plant) Corn - Zea mays  Amylase is an enzyme, or special protein, that helps you digest carbohydrates. Bones Bugs and Botany Patreon Soul Food Genius Course by Bones, Bugs and Botany ________________________ Follow us on social: ⁠@pettyherbalist⁠ ⁠@bonesbugsandbotany⁠ Join the Patreon Community to fund this amazing POD: ⁠https://www.patreon.com/pettyherbalist⁠ Join the bonesbugsandbotany Patreon Community to fund support all of Asia's work: ⁠⁠⁠https://www.patreon.com/bonesbugsandbotany⁠⁠ Rate us to show your support! Thank You! #StayReady #BePetty ***if you read this far, send me a dm @pettyherbalist for a shoutout!***

In this episode, Drew Lyon talks with Adam Johnson about the new alpha amylase test being developed through public-private collaboration. Resources: Envirologix: envirologix.com Arising the falling numbers rapid test with Drs. Hauvermale and McCubbin: smallgrains.wsu.edu/wbp181/ The upsides of a Falling Numbers immunoassay rapid test with Dr. Amber Hauvermale: smallgrains.wsu.edu/wbp165/ Contact information: Envirologix: 207-605-5894 Episode transcription: smallgrains.wsu.edu/wbp185

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WSU Ph.D. candidate Elliott Marston shares recent findings about late-maturity alpha amylase, one of the causes of low falling numbers. Episode transcription: https://smallgrains.wsu.edu/wbp169/ Deven See's Faculty page: https://plantpath.wsu.edu/people-directory/profile/?nid=deven_see Western Regional Small Grains Genotyping Lab: https://plantpath.wsu.edu/people-faculty-see-see-lab/ New grant to help grain farmers find low falling numbers sooner: news.cahnrs.wsu.edu/article/new-grant-to-help-grain-farmers-find-low-falling-numbers-sooner/ Washington Grain Commission: wagrains.org/articles/falling-number-research-receives-ffar-grant/ WSU Wheat & Small Grains website: smallgrains.wsu.edu

Kirby begins with a description of the mechanism of amylase-enhanced corn. The amylase is located in the kernel and, once activated by temperature change, works to increase the digestibility of the starch. A small amount of activation is thought to occur during silage fermentation, with further activation once it reaches the rumen. This paper evaluated digestibility and milk production in cows fed corn silage made from a hybrid with the amylase-enhanced gene compared to the same hybrid without the genomic enhancement. (4:51)The experiment was designed as a factorial with four treatments combining the two different types of silage with either 25% or 30% starch in the total diet. Only the silage was amylase-enhanced, not the corn grain that was fed. Kirby expected the amylase-enhanced silage group at 25% starch to perform best because he expected some subclinical rumen acidosis and potentially some feed intake issues at the higher dietary starch concentration. (9:09)The experiment was eight weeks long, consisting of a two-week covariate and then a six-week feeding period with 11 cows on each of the four treatments. Blood and milk samples were collected weekly. Total tract digestibility was evaluated twice over those six weeks, once soon after silage harvest (approximately 40 days) and again six weeks later to evaluate whether the impact or efficacy of the enhanced starch enzyme changed over time. (13:29)One surprising result was that the two silages had different in vitro NDF digestibility during week one of the feeding period. The amylase-enhanced silage had higher fiber digestibility even though the genomic enhancement is for starch digestibility. Kirby is unsure of the mechanism but hypothesizes that the amylolytic enzyme may free up some simple sugars or polysaccharides that allow microbes to have greater action and more energy available to digest fiber. By week six, the in vitro NDF digestibility of the two silages was essentially the same (15:09)Kirby mentions that if he could do this experiment again, he would do a longer-term study for 12 or 18 weeks and start feeding the silage as green chop right away to evaluate if ensiling takes away some of the benefits of the amylase-enhancement. (19:02)From the production data, the alpha-amylase enhancement didn't provide a benefit, but a fairly consistent benefit of additional dietary starch was observed, including increased feed efficiency, increased energy-corrected milk, and increased milk protein yield with few to no interactions in these results.Kirby also would like to have some data looking at the impacts of these types of diets on fresh cows since the cows in this experiment averaged 160 days in milk at the start of the feeding period. (24:11)The alpha-amylase-enhanced silage did not impact body weight, body condition, or feed intake. Kirby anticipated that the higher starch-fed cows would experience greater body weight gain in the later lactation period, but he observed the opposite. At the end of the study, an interaction was observed for feed intake where the high starch cows ate a little less - around three pounds. This resulted in a difference in feed efficiency for the high starch cows, where their intake decreased, but they maintained milk production. (25:29)Bill asks if the feed efficiency data was adjusted for the difference in body weight change, but Kirby responds that it was just gross feed efficiency, milk over feed. Bill wonders if that adjustment would make the two groups' feed efficiencies closer together, where it's more of a difference in how nutrients are being partitioned rather than a difference in feed efficiency (27:26)Another follow-up experiment Kirby would like to conduct is another factorial with the enhanced silage variety and the non-enhanced combined with a higher and lower rumen degradable protein concentration. (35:16)Bill wonders if this experiment was conducted with silage at a later maturity, say 40-42% dry matter, would the amylase have a bigger effect? Kirby thinks there is a chance that as the kernel dries down, the amylase may have a greater impact. (38:53)Kirby's take-home messages for the audience are to consider the amylase-enhanced gene as an approach to bridging an inventory challenge gap from year to year and not to avoid dietary starch due to worries about subclinical inflammation. Kirby's paper can be found here: https://www.journalofdairyscience.org/article/S0022-0302(23)00309-0/fulltextPlease subscribe and share with your industry friends to bring more people to join us around the Real Science Exchange virtual pub table.  If you want one of our new Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll get a shirt in the mail to you.

Normal 0-130 U/L Indications Diagnosing: Pancreatitis Pancreatic Duct Obstruction Macroamylasemia Trauma to Pancreas Description Amylase is made in the pancreas. It is an enzyme that breaks down carbohydrates to allow our body to absorb it. Monitoring amylase levels can help identify problems with the pancreas. What would cause increased levels? Pancreatitis Pancreatic Cancer Pancreatic Cyst DKA Peritonitis Abdominal Trauma Duodenal Obstruction Mumps Alcohol use What would cause decreased levels? Pancreatic Insufficiency Pancreatectomy Toxemia of Pregnancy Cystic Fibrosis Liver Disease

Wondering why your hormones are all out of whack? Ever feel like you're maintaining a delicate balancing act, but the scales just can't stay in place? Well, if that sounds like you, then it's time to join us as we dive into Dr. Norm Robillard's fascinating insights—on how an unhealthy gut might be disrupting your hormones. With decades of experience under his belt and countless research studies to back him up, this is one episode on midlife hormone balance that no woman should miss!   Norm Robillard, Ph.D., is the founder of Digestive Health Institute and creator of the Fast Tract Diet. He is a strong advocate of natural and integrative solutions for functional gastrointestinal disorders, various forms of gut dysbiosis and related health issues, helping people globally through his consultation practice. The Fast Tract Diet was presented at Digestive Disease Week to give gastroenterologists a science-based treatment option for functional GI disorders and dybioses based on Dr. Norms 3 pillar approach. His award-winning Fast Tract Diet mobile app and Fast Tract Digestion book series make it easy to implement the Fast Tract Diet.   In this episode, you'll learn: • How an unhealthy gut may affect your hormones. • What Dr. Norm's 3-pillar approach is and how it could help rebalance hormones. • The importance of probiotics in maintaining healthy gut flora. • Why food sensitivities can play a role in hormone health. • Plus, Dr. Norm shares his top tips for keeping your digestive system functioning optimally!   So don't miss out – join us as we explore why your dysfunctional gut might be wrecking your hormones and what to do about it with our incredible guest, Dr. Norm Robillard! Tune in now—you won't regret it!   Midlife women - let's take back our health and nurture our bodies, together! Join us for this eye-opening episode on why your dysfunctional gut is wrecking your hormones and what you can do about it with Dr. Norm Robillard! Tune in now to learn the secrets of a healthy digestive system and balanced hormones. It's time to start feeling like yourself again!   (00:00): “The best doctor gives the least amount of medicine.” - Benjamin Franklin. If your gut is dysfunctional and running you crazy and you think you've got hormone problems, this episode is for you. (00:13): So the big question is, how do women over 40 like us keep weight off, have great energy, balance our hormones and our moods, feel sexy and confident, and master midlife? If you're like most of us, you are not getting the answers you need and remain confused and pretty hopeless to ever feel like yourself Again. As an ob-gyn, I had to discover for myself the truth about what creates a rock solid metabolism, lasting weight loss, and supercharged energy after 40, in order to lose a hundred pounds and fix my fatigue, now I'm on a mission. This podcast is designed to share the natural tools you need for impactful results and to give you clarity on the answers to your midlife metabolism challenges. Join me for tangible, natural strategies to crush the hormone imbalances you are facing and help you get unstuck from the sidelines of life. My name is Dr. Kyrin Dunston. Welcome to the Hormone Prescription Podcast. (01:06): Hi everybody. Welcome back to another episode of the Hormone Prescription with Dr. Kyrin. Thank you so much for joining me today for this discussion on dysfunctional gut issues. What's a dysfunctional gut? Well, think about your dysfunctional family. You know what I'm talking about, right? Holidays where people get drunk and fight start, or people are disconnected, all the dysfunctions that plague modern families. Well, your gut can be dysfunctional too, and maybe it's not something that you're aware of. What does that mean? How you evaluate it? My guest today is an expert in this and he is going to help you understand clearly how do I know if this is me, how do I get tested, what do I do about it? And really get the big picture and detailed picture on what's important. And we're gonna talk about Benjamin Franklin's quote, the best doctor gives the least medicines, not the most. (01:57): I know some people who go to the doctor and actually get angry when they don't leave with a prescription. Is that you? I really hope not, but it's very true. A lot of people get angry when they don't get medicines, but you'll be healthier overall when you take fewer or no medicines. They don't really fix the problem, they just mask them. Your gut health and microbiome are essential for your hormonal health. I will tell you why in this episode. So you wanna stay tuned for that. We talk about assessing low stomach acid at the Heidelberg Test. If you're not aware of that, we dive into that and much more. So I'll tell you a little bit about Norm and then we'll get started. Norm Robard is a PhD. He is the founder of Digestive Health Institute and creator of the Fast Track Diet is a strong advocate of natural and integrative solutions for functional gastrointestinal disorders, various forms of gut dysbiosis and related health issues, helping people globally through his consultation practice. The fast track diet was presented at Digestive Disease Week to give gastroenterologists a science-based treatment option for functional GI disorders and dysbiosis based on Dr. Norm's three pillar approach, his award-winning fast track diet, mobile app, and fast track digestion book series make it easy to implement the fast track diet. Welcome Norm Robillard to the (03:24): Show. Thank you Kyrin. Nice to be here. (03:26): All the way from Boston, Massachusetts with a distinctive accent. I did live there one summer when I worked at the Harvard School of Pub Public Health doing research and it's such a unique accent that I would pick out anywhere I went in the world. So thank you for representing the Northeast (03:45): , right? In fact, I've lived in California for 10 years and I came back and I still have the accent , (03:52): Right? So let's dive into this very important topic. We can't talk about digestive health enough when it comes to hormonal health. And if you're listening and you're still scratching your head going, Kyrin, I don't know why you talk about poop all the time. This is supposed to be about hormones, . You gotta get the memo that your poop is all about your hormones and your hormones are all about your poop. So there's this interconnection. So what really was your path to becoming so passionate about functional gut disorders? Well, let me back up. Let's start with what are functional gut disorders? I don't even think people are familiar with that term. (04:32): Yeah, well they should get rid of that term as quickly as possible. It's been around a long time and it doesn't have much meaning now because when that term came up, it was, they couldn't find anything organically wrong with you. But yet you had these i b s type symptoms, bloating, altered bowel habits, gas belching, and so they would think, okay, well everything's working, but you have these symptoms. So it's a functional disorder. But we now know that in many of these cases, really the planes hit the mountain. It's not functional and we know a lot more about what's going on. You know, with the more common use of breath testing. We know that there's often an overgrowth of bacteria in the small intestine and there should be very few microbes in the small intestine. That's where our own critical digestion takes place. So we now know there's overgrowths and there there's been some studies on which exactly which types of bacteria those are. (05:34): And basically it's our own microbes overgrowing in the small intestine. And newest studies are starting to focus on some of these what they call proteobacteria like e coli and Klebsiella species. But others have been identified as well, also with various functional, what they used to call functional GI issues. They now know that there's alterations in or intestinal bacteria as a whole. So we have these FILA of bacteria and other organisms such as BDIs firm, acutes, actinobacteria and so on. And we know that there's some significant imbalances there in in people that have these conditions. So in other words, we're find as we find out more about them, they're not functional, they're dysfunctional gut health issues. So it, you know, takes 10 years for things to catch up with what's actually happening in terms of nomenclature and the dogma and the literature. Right. (06:33): I agree. We should call it dysfunctional gut disorders, just like we have. Some of us have dysfunctional families, dysfunctional gut disorders. Exactly. So you mentioned symptoms of ibs. So how would someone self-identify? I could have a dis or now I'm saying I could have a dysfunctional gut disorder or I could have a functional gut disorder. How would they consider that that might be them?  (06:56): Yeah, well I think that the symptoms of the, kind of the first sign, right? I mean we talked about gas and bloating. You might have a lot of belching or even flatulence, kind of some lower GI gas you might have cramping, reflux is one of those. In fact, acid reflux and I B s are very closely linked. Half the people with IBS have reflux symptoms and half the people with reflux have IBS symptoms. So there's a similar etiology there, but there's other ones, nausea, dehydration, fatigue. Some people don't gain weight or they lose weight. So there's a nutritional component there, which makes sense, right? If you have all of these microbes in your small intestine where, where your vili and the micro viop kind of the, the fibers on top of fiber fibers in all of the surface area in the small intestine, these vili are pretty kind of delicate. (07:51): And if you have a lot of bacteria in that area and bacteria produce toxins and protease enzymes that can damage the vili and the little enzymes, the brush border enzymes that that radiate out from these microvilli. And so if you don't have those, you won't break down disaccharides, you won't complete the final breakdown of starches. You may not digest and absorb fats well. So the SIBO can cause this mal-absorption that ends up overfeeding these microbes. And when you overfeed these microbes, many of them produce significant amounts of gases. Hydrogen methane, hydrogen sulfide. In fact there was one microbiology study done on these gut bacteria. And if they feed these bacteria essentially one ounce of carbohydrates, right? So some, many of the carbohydrates we absorb into our bloodstream, but many we don't. We take just 30 grams of unabsorbed carbohydrates feed them to, to microbes these gut bacteria. (08:56): They can produce 10 liters of hydrogen gas. So imagine, whoa, 10 liters of gas in your intestines from one ounce of of unabsorbed carbs. And of course there's a molecular food chain. Some microbes take the hydrogen that one type of bacteria produces and they turn it into methane. In the case of these akea organisms or sulfate reducing bacteria can take the hydrogen and turn it into hydrogen sulfide. So the bottom line is when you're not digesting and absorbing your food efficiently, you're overfeeding these microbes. They produce a lot of these gases and you can end up with a lot of these symptoms. So I think the symptoms to answer your question is the first sign that something's going on. And then you have to really begin to look deeper into what's happening. (09:43): Right? So just to recap, cuz that was very rich, what you just shared is if you're wondering could I have a functional gut disorder? Basically if you have any of the symptoms that Dr. Norm is talking about, right? The excess belching, indigestion, heartburn, reflux, gassy if you poop less than every time you eat, right? So if you have any degree of constipation, if you have loose stool, hard rabbit pellet stool, you know any symptoms associated with a gastrointestinal tract that wouldn't be diagnosed typically by your regular H M O doctor cuz they're looking for a structural problem or maybe they would diagnose you with reflux, but they're basically gonna give you a drug for it. Can you talk about the pitfalls? Because some people listening are gonna think, oh yeah, I've got reflux, it's no problem. My doctor gave me this proton pump inhibitor and so I'm fine now. I don't have a problem anymore. Dr. Norm. Yeah, what what do you say (10:45): To that? Yeah, my 18 years of consulting in this field as a consulting microbiologist, I really focus on holistic and dietary and behavioral solutions and perhaps some dietary supplements mostly aimed at improving digestion. Because I recognize that these proton pump inhibitors, for instance, and to a lesser extent H two antagonists, these types of medicines, they basically knock out the ability of your stomach to produce acid. And so when you do reflux and material comes from your stomach and gets up into your esophagus, it might not burn as much. And about half of the people with reflux get symptomatic relief from those types of medicines. Half don't. But the real issue is why are you refluxing? That's what you need to address. Because it's not just acid, it's stomach enzymes, pepin, it can be pancreatic enzymes when they look they find bile, right? Bile is something, it's a caustic molecule. (11:50): Your liver produces these bile acids stored in your gallbladder, released into your small intestine to help digest fats. And all of these other functions are antimicrobial. But when they reflux back into your stomach and then into your esophagus, they're caustic as well. And the proton pump inhibitors won't do anything about those. And then on top of it, this long-term health consequences of removing your stomach acid. Mm-Hmm. , you may very well have not absorb vitamins like vitamin D, certain B vitamins, B12 because your stomach makes intrinsic factor that that is needed for B12 absorption. You might not absorb iron as well. Magnesium in particular, in fact on proton pump inhibitors, there have been cases with this hypomagnesemia low blood mag magnesium, which is a dangerous condition, cardiovascular metabolic health and even supplementing with magnesium doesn't always correct the issue. So there are long-term consequences of these drugs. And when I work with people, there may be a reason they need to be on a PPI to begin with. Say they have gastritis or an ulcer. Well that is one instance where those can be helpful, but the goal should be really healing that and then giving reflux under control and then getting off of these acid reducing medicines. I've worked with people that have been on them for 20 years. It's a problem at that point. (13:19): Yeah, it's, I think they're really only approved for short-term use, but doctors put people sometimes on these who are taking them for years and it just decimate the rest of your digestive tract, which affects your hormones. Ladies (13:35): . Yeah. And your microbiome. There's a number of studies saying that, that reducing the stomach acid on these drugs drives changes in your microbiome. So natural is always the best whenever possible. , that's my motto. (13:50): So we can't talk about the microbiome enough. We've talked about, you know, how would I know if I had a functional gut disorder? Well actually let's go into this next. What type of evaluation should people be expecting to have if someone really is doing a root cause resolution approach and looking at why they have a dysfunctional gut issue, what kind of testing is available and should they look for an ask for? (14:13): What I routinely use in, in my consultation practice is comprehensive stool analyses. Now those results won't necessarily tell you whether you have sibo. All right. Small, an overgrowth of bacteria in your small intestine. It's really looking at the composition of your stool. However, first of all, there are many types of dysbiosis. SIBO is one of them. There's also cifo, small intestinal fungal overgrowth. There's libo, what I loosely call libo for an overgrowth in urological biological intestinal overgrowth. And it's based on a couple of studies that are very convincing that you can't have an overgrowth in the early part of your secum and large bowel as well. Mm-Hmm , you can have these methanogens overgrowing that's called imo, forint intestinal methane overgrowth, people that are making too much methane. But you can also have significant imbalances in the composition of the gut microbes in your lo intestine. (15:11): Right. And when you have that, what are the ramifications of that? So in these stool tests, first of all, you're going to look at a lot of other digestive markers. You're going to look at elastase, which is an enzyme produced from the pancreas. That is an important test. A lot of doctors use just that test itself to determine whether the pancreas is functioning and release, releasing other important digestive enzymes like amylase, lipase and protease. Elastase is just the test they use to assess the pancreas. You're looking at S I G A, secreted immunoglobulin A. In other words, how's your gut immune system doing? I G A is important for gut barrier integrity, for balancing the good and bad microbes. You're going to look at a whole variety of pathogens that may be your problem, right? You can roll in certain other testing, helico, pyuria, bacteria, infect stomach, clostridia, difficile, especially if somebody has chronic diarrhea. (16:14): But then you also look at all of your, what I call commensal populations, right? The bacti, the firm acutes the proteobacteria on and on, right? A number actinobacteria bifidobacteria. And then you wanna know what do your populations look like in each of those high level and detailed species level breakdown compared to kind of the healthy consensus population. And so it takes a trained eye to really go through these tests, but there's a lot of actionable information in there when you do that. So for instance, what I like to see right off the top, I like to look at the firmicutes and the bact ADIs because those two Fila rep like and Utes are like bacillus and strap. And some of those species, lactobacillus, those are all Utes, bact, ADIs, that's bact, fragiles, bact theta, ITO micron and so forth. They're highly diverse, these two Fila. (17:16):And they represent 90% of the microbes in your gut, just these two Fila. And so the ratio of those is really important. If you have a lot of these firmicutes over the BDIs that's commonly seen in I B s, it's commonly seen in epilepsy, it's commonly seen in obesity. And it's also common on a plant-based diet. If you eat a lot of plants and your digestion is working well, you may have too many of these firmicutes on an animal-based diet. There's more of the BDIs. And also that's more indicative when somebody is addresses i b s or addresses obesity or addresses the epilepsy. You see that shift. So there's just so much to look at in these comprehensive stool analyses, but there's some of the highlights. Yeah, it's very false. (18:06): Yes. And I'm wondering if you can speak to the utility of, I'm not sure if you look at this cuz you come from it, gut health from a microbiology standpoint, but food sensitivity testing. And then if you could comment on, are these types of tests that your regular H M O doctors going to order and know how to read? (18:26): Mm-Hmm. Yeah, that's a good question. Not all of them. Although if you go to certain websites of some of the companies that do this test, like Genova, they have a GI FX test, very good test. I use it often. If you drill into their website, they will point you in the direction in your state to doctors that routinely have accounts with them. You know, for instance, our Digestive health Institute has an account with direct labs, so we can get the test that way, but they'll point you in the direction of doctors that can order these tests. And you brought up an important point. You mentioned food sensitivities and while we're at it how about just kind of inflammatory conditions? Mm-Hmm. . And there are markers in this same test that look at that. For instance, calprotectin. Calprotectin is a protein released from activated white blood cells at the site of inflammation. (19:17): And so if you have high levels of calprotectin, you're in an inflammatory state. Now it might be just a couple of hundred and okay, that's still high and you need to address it. But somebody with inflammatory bowel disease for instance, they might, might have levels. And I think the units are micrograms per gram of 2000. So it can tell you a lot. Now in terms of food sensitivity, there's EO eosinophil, protein X mm-hmm . And that's considered a marker of kind of food sensitivity. So that's another one you can look at. You can look at lactoferrin, you can look at if there's microscopic signs of blood in your stool because that's another sign potentially of inflammatory bowel disease or even colorectal cancer. So there's a lot in these tests and it's a really good thing to do if you have a lot of gut issues and, and you need to try to understand why and what to do about (20:14): It. Yes. So I love these tests. I usually use the GI map, that's my favorite. It gives a lot of those markers that's, and you know, I was thinking earlier when you were running through the different species, the bacteria, some people will get tripped up thinking they have to know all these different names. I mean it's helpful if you do, but it's kind of like your friends at church that maybe you know their face but and you wave high, but you might not remember all of their first and last names. You don't need to. So don't feel like it's something that you have to memorize if that trips you up. But you can just learn the ones that are most important. Just like in your communities where you have friends who you know their first and last name, you know where they live, you know their phone numbers. (20:56): So it's a similar type of community. So consider if you are a candidate for functional gut testing, having some of these tests, food sensitivity is something that I, I really recommend. I don't think there's a perfect food sensitivity test, but I think they all have their pros and cons. So you kind of have to, whoever you decide to work with, I do think having a guide with these types of things is very helpful. Pick which one could work. So tests, don't guess get an evaluation. What are some of the common things that we can do though maybe we can't afford testing. This testing is not inexpensive. I know. Mm-Hmm. , you know, the GI effects with Genova and the GI map or $500 or more. So not everyone can afford that. So what are some steps that people who are having functional issues with their gut might mm-hmm. just start to take from a general basis that could impact how their gut is functioning. (21:57): Yes. In fact, you can do a lot. In fact, I'll usually start, if there is some testing, especially GI testing or say a SIBO breath test, I will like people to get those samples done before they start kind of some interventions. But oftentimes we'll just work by just taking a complete history of somebody, you know, how long has this been going on? Exactly what are your symptoms, what is your diet like? Is really an area that I dig deep into because I work with people that have very varied dietary preferences. I work with vegetarians, pescatarians, mostly omnivores, but a good number of vegetarians and pescatarians and once in a great while of vegan as well. But it matters because we had talked about this molecular food chain, right? When you consume food, right, it consists of proteins, fats, and carbohydrates, right? Those are the three food groups. (22:54): And while the microbes in our gut can utilize some of the amino acids from proteins for energy, there are some bacteria, these sulfate reducing bacteria for instance, that no tricks how to get energy from fats. It's not a high energy deal, but they can do it. But the microbes in our gut get most of their energy from carbohydrates. So if you're on a plant-based diet, you are consuming a lot more carbohydrates. And the five that I really focus on, and I look for when I, when people tell me what they're eating is fructose and lactose. Two sugars that tend to be difficult to digest, to absorb. And in the case of lactose digest with lactose intolerant people, but also resistant starch fibers and there's a huge variety of fibers and sugar alcohols. There's many sugar alcohols difficult to digest, but yet all of these are fermentable by microbes. (23:51): And by the way, there is one kind of gut-friendly sugar alcohol called erythritol that won't drive these overgrowths and all this gas that we've talked about, but the other species can, if you're not digesting and absorbing these foods, well in fact we don't digest fiber by definition that you can overfeed these microbes. And there's a common belief these days that we're actually starving our microbes, that we need to eat more fiber and more fermentable material. More of these five types that I mentioned. I reject that if somebody's perfectly healthy and they're not having any of these GI issues, okay, I won't, I won't chime in, but for people that are having a lot of gas, altered bowel habits, bloating, all of these symptoms, I will really look closely at their diet and then focus in on their digestion and say, what, what's wrong here? Why are these microbes being essentially overfed in your case? (24:47): And so it gets to kind of the mechanistic part of it. And so if you had to break down the fast track diet, that's a diet I created. I've written a couple books on it or my consulting practice, I always focus on these three important areas, diet and digestion, right? What are you eating and is that diet matched with your ability to digest and absorb those nutrients efficiently or is there a, a mismatch? So diet and digestion is big. And then the next part is root cause analysis, right? What are these potential underlying or contributing causes? As many of these, you know, probably a hundred if you consider the rare ones, but 25 or 30 or 35 are relatively common and they won't be common to everybody. So we have to, in most cases rule most of them out to really focus in on what is the most likely underlying cause or causes in that particular case. (25:45): Cuz it's somebody that has hypochlorhydria, low stomach acid and there's all these risk factors and reasons for that. Is it somebody that has pancreatic insufficiency, right? We talked about the elastase test to measure that. But even if you don't it say you can't afford the stool test, you can just try a digestive enzyme that contains pancreatic enzymes. And the same goes with these brush border enzymes, these disaccharides, lactase, sucres, maltase, iso, maltase tris, it's many of them. They can be damaged on the brush border. It's not easy to get that test done. They usually use that test for kids with genetic deficiencies in these enzymes because it's a very dangerous condition. But we now know in adults with these functional GI issues, I, I'm using the term too dysfunctional GI conditions, right? , they, it's very common for them to have these brush border deficiencies. We now know very recent work up to 70% or more have these deficiencies. (26:44): Testing requires endoscopy, taking biopsies, send it to highly specialized labs, probably expensive. But instead there are also digestive enzymes you can get that have brush border enzymes. So these are kind of workarounds. You can say, well this testing is too much, it's too involved. Instead I want you to try this particular dietary supplement that has either the pancreatic or the brush border enzymes and let and of course modulate your diet. I almost always recommend people to significantly reduce their overall levels of carbohydrates. Any more proteins and fats for the reasons I stated that those are less invasive or less li likely to drive overgrowths and dysbiosis. So reduce the carbs and then reduce in particular these five types of carbs I mentioned. And if you have a brush border deficiency, even the easier to digest starches may be a problem. In the fast track digestion books, I I break down starches into two groups, resistant starch starches that have more of a starch called amlo. (27:53): It's harder to digest or le or less resistant star, which has more amylopectin, an easy to digest species of scotch. So jasmine rice and sushi rice, it's an easier to digest scotch, uncle Bens and wild rice and bosma rice, more of the resistant scotch. So I'll say, well if you're going to have starches stick with jasmine or sushi rice, I'll, I'll add some particular name brands that I like and cook it properly in a rice cooker if possible with plenty of moisture. And then limit your serving size, right? When you cut your serving size from a cup down to a half a cup, you cut these fp points that it's a calculation I created in the book to measure how much of these fermentable carbs you're consuming on whole. When you cut your portions in half, you cut these points in half and you cut your symptom potential in half. So I'll say eat less, follow these particular behaviors and practices or just avoid starches for the next month until we really get to the bottom of this. (28:55): Yeah, I, you know, and when from a hormonal perspective, when you're saying sushi rice or jasmine rice, those are white rices, I'm thinking immediately, oh that's gonna mess up your insulin. Don't do that. Just don't eat it . No, but I hear very good point. I hear what you're saying looking at, yeah, right. So we've always gotta consider, you know, gut health with hormones and then hormones, he hormone health with gut health. And I think when we neglect one, we neglect to think about the other when we're, we're addressing one part that we can cause more problems. But yeah, so diet is super important. Sometimes you just can do empiric treatment if you can't afford testing, you can try a brush border enzyme or try adding retain and Pepsis. And I remember when I worked at the, the clinic in Atlanta, you know, getting at what is your stomach acid level? Do you have hypochlorhydria is really hard. Although most people over 30, and especially with each advancing decade, we increasingly have it till when we're in our seventh decade almost all of us have hypochlorhydria, meaning not enough stomach acid. So we actually had a Heidelberg machine (30:05): , huh, wow, good for you to (30:08): Test, right? Like who has (30:10): That's (30:10): Impressive Heidelberg machine. (30:11): Yeah. (30:12): Right. So some people are listening, you're going, what is a Heidelberg machine? So like I said, getting at a measurement of your exact stomach acid level is very difficult. But with the Heidelberg machine, you swallow a capsule and then it radio transmits the pH level to a de sensor outside and you get a computer readout of how your stomach acid changes over time in response to certain things. And it's this beautiful test. But like I said, you don't really need that test. If you're over 30, you probably have some degree of hypochlorhydria. You have gerd, you definitely do. If you've been on a P P I, you definitely do. So sometimes you can just treat empirically as that kind of, what is your approach to stomach acid disorders? Mm-Hmm. . (30:56): Yeah, no, that's very good. And I, I wanna get into that, the Heidelberg and also risk factors for low stomach, but just wanted to comment on something you said earlier. Yeah, you bring up a very good point about, okay, the, the rices I mentioned that are less problematic for your digestion also going to raise your blood sugar more, right? They're higher glycemic index, right Rices, right. The bosma and Uncle Bens is a lower gi, lower glycemic index and higher FP and the jasmine rice and sushi rice, a higher glycemic index, higher gi, but lower fp. So they're easier on your digestive tract. If you have, you do need the brush border enzymes though, which complete the breakdown of starches. Amylase doesn't do all of it. You need the brush border enzymes as well. But let's assume they're working. And so Jasmine rice is a good fit for you in terms of your digestive wellbeing, but it, it is going to raise your blood sugar. (31:47): And that's a point I do bring that up in my book. And that's one of the reasons we also recommend smaller servings of high GI, low FP foods because they will raise your blood sugar and the last thing you want to do is get into a situation with metabolic disorders or pre-diabetes or even diabetes, you know, insulin related illnesses. So we're very cognizant of that. So we know there is that trade off and so I'm glad you brought that up. Regarding stomach acid, this is really fascinating and I, I agree with you. Some people will just kind of say, well you're on a P P I when you get off the P P I, we're gonna make a lot of changes in dietary and behavioral changes get you off the PPIs and hopefully your stomach acid will pump back. Might be that simple. But for a lot of people they could have significant issues. (32:33): They may have pernicious anemia. It's an autoimmune condition where your own antibodies are attacking these parietal cells that produce the stomach acid, right? And you wanna know about that if you have it. And of course you may also have low B12 levels because intrinsic factor is needed for absorption of b12, a Heidelberg test. And it's just fantastic that you once had one. I too bad. You can still have it. You can. I just received one of those test results this morning from one of my clients and was going through it. It's an amazing test. But before I recommend that to somebody, I really do look at the risk factors for hypochlorhydria and there and there's some risk risk factors for hyperchlorhydria too. Too much stomach acid. Mm-Hmm . But I look at whether they have had an endoscopy before. If they have gastritis, that's a big risk factor. (33:22): And often gastritis is caused from a chronic infection with this bacteri helico back to Pylori. And so I wanna make sure they've been tested for helico back to Pylori. You can get it in a stool test, there's a breath test for it and so forth. I wouldn't recommend the blood test because that will just tell you whether you've ever had it. You wanna know whether you have it. So gastritis, whether you're h pylori positive or negative. If you abuse NSAIDs, non-steroid anti-inflammatories like aspirin and ibuprofen, that's very irritating on the stomach. Can lead, can lead to gastritis if you had Hashimotos, right? Hypothyroidism, autoimmune hypothyroidism, you're at greater risk for pernicious anemia. And so there's more of these. So working through these risk factors, I can usually reach a point where I can say, you know what, you're at very low risk for hypochlorhydria, let's move on. (34:11): But if the answer comes back and says you're at a moderate to high risk for it, we might either take some action steps or let's look for a place near you, a practice near you that has the Heidelberg. So it's just, it's great you brought that up. And when you go to the Heidelberg website, I forget what the name of the website is, but if you just google Heidelberg acid test, you'll see the website. They do have by state places that still do the tests so you can find them. I'm really frustrated that every teaching hospital in every state doesn't have the ability to do this because for people that that aren't familiar with the test, you are not just measuring whether somebody has acid or not in their stomach, as you mentioned. You take this capsule, you swallow it, but it dangles on a string and they, and by the pH right, it radios up to a laptop and by the pH being really low you can see, okay, you're in the stomach and that's, they might put a piece of tape there and you know it's sting in the stomach. (35:08): But the secret to that test is you can now tell what your stomach acid is and that capsule isn't going anywhere and they give you these drinks of sodium bicarbonate. Mm-Hmm That will raise the stomach acid back closer to neutrality six or six and a half, seven. And then they see how long it takes for your parietal cells to produce enough stomach acid to lower the acid back down to between pH one and two very acidic. And if it takes a real long time, then you may be diagnosed with hypochlorhydria. Now if it does it in 10 or 15 minutes, okay that's okay. But then they'll give you another drink and then once the stomach acid regains itself, they'll give you another drink, three or four of these. And so you can see if your stomach can reas acidify each of these times. If you end up with a space of about 40 or 50 minutes or an hour, then that might indicate that you have hypochlorhydria, your stomach just isn't able to keep up Reac acidifying itself. (36:06): Yeah. And you know, after I was so excited to get to work with this machine, but I have to say after, you know, hundreds reading hundreds of these tests, I've never seen one in a human over 40 who wasn't having health problem, who was having health problems that wasn't abnormal. So I do think it's (36:25): A great test. Well I seen, I've seen both and I've, I had one client that we suspect that he had low stomach acid. He was actually a hypers secret (36:32): Secret, very interesting. (36:33): Five minutes every time just making right stomach acid. So, and that can happen if you have dysregulation of gastro producing cells in the lower part of the stomach, which when those are expressed to stimulate stomach acid, they stimulate histamine release and that binds to the bridal cells and drive stomach acid. So there are a lot of possibilities that you pyloric sphincter in how healthy that's working can allow reflux from the small intestine back into the stomach that can throw off stomach acid results. So there's a lot of things to consider. It can be a little bit complicated, but I still think it's a great test right to look at in some cases. (37:14): I do too. I wanna tie everything we're kind of talking about together with hormones for everyone because I know some people are still wondering K Kiran, why are you always talking about poop , we're supposed to talk about hormones so I just wanna tie it in as succinctly as I can. But your gastrointestinal tract is actually your biggest interface with the external environment. I know it's on the inside of your body, but you're taking the external environment and you are putting it inside of you. The surface area of your gut is as big as two doubles tennis courts, which is way bigger than the surface area of your skin. So everything you take into your mouth is contacting you. So it being the biggest contact with your external environment, it is the highest concentration of your immune system designed to protect you. It's your body's military all along your gastrointestinal tract. (38:09): And that is directly related to your cortisol. Stress hormone is directly related to your immune system function is directly related to your gut function. So if your gut isn't right, your immune system's not gonna be right and your cortisol's not gonna be right. And your cortisol, I call her queen cortisol, is going to wreck havoc with your sex hormones. So you might have PMs heavy painful periods and you think all you've got is a period problem. No, you could have a gut problem or it's gonna wreck havoc with your thyroid hormone and you think you've got a thyroid problem cuz then you're overweight and tired and you don't have a primary thyroid problem, you actually have a gut problem. So if you listen to me long enough, you know what I'm talking about. If you're still scratching your head going, what in the world is she talking about? (38:55): Keep listening, come meet me on social media, join one of my challenges, we will get you up to speed on why your PU poop is good. Poop is essential to hormone health. Thank you Norm for furthering the understanding for everyone today in a very deep and meaningful way about functional or dysfunctional gut disorders. Before we wrap up, I wanna just ask you a couple things. The first is you shared a couple quotes with me before we started that I absolutely love and you said from Benjamin Franklin, whom I love the best doctor gives the least medicines. Mm-Hmm , can you talk a little bit about that and then we'll go ahead and wrap up? (39:38): Yeah, well in my fast track digestion books, I use a different quote at the beginning of every chapter. So I kind of like you, I love those. And the back one is your health depends on the bacteria in your gut. So I think that sums up a lot of what we were talking about. But in terms of the best doctor gives the least medicine, I mean I've really come to believe that and I've, I've been on both sides of the fence. I spent the first 20 years of my career after graduating from school in the Fama biotech industry developing new drugs. And I like the idea of working on these difficult diseases with unmet medical needs and coming up with, with a drug or a solution that that works for these serious conditions. You know, for, and I spent 10 years just on antibiotics and they're lifesaving medicines. (40:27): I worked on the development and approval of ciprofloxin. They're lifesavers but they're also really rough on the gut. And so when I see more and more of these kind of strong medicines being used for people with these digestive health issues that I think could better be addressed by holistic means, especially antibiotics, because those are, those really disrupt the, the microbiome. It drives me crazy, but I think it's both the manufacturers that make money on the drugs, on the doctors, it's easy to prescribe something, but also patience. Well, I can just take this pill and keep eating what I want to eat. That sounds like a (41:07): Good deal . But (41:09): So when I work with people, it does take, you have to be willing to make some changes and to really look at things in a way that, you know, you may have to change your diet and change your behaviors and try some more holistic supplements. We talked about digestive en enzymes as many, many others and get away from these harsher drugs. So that's what that means. So first chapter of that fast track digestion, i b s book is all about the drugs for i b s and the conclusion at the end of it is it's a big fail. They, they're terrible and so we need to find a different way. (41:42): Right. Awesome. Well everybody, norm is giving you a free copy of his hashtag Diet 1 0 1 ebook. We will have the link in the show notes, so definitely encourage you if you have dysfunctional gut issues to download that and read that. Tell everybody where else they can find out more about you and the work that, that you do. (42:02): Sure. Every aspect of our work and also our consultation services, blogs, information about the fast track digestion books is one on i b s and Hot Burn. The Fast Track Diet mobile app I haven't really talked about. But this mobile app is, is just the greatest way to implement the diet. It uses this FP calculation and so there's, it's got a database of over 1200 foods and their FP values and a calculator to calculate this fp value for foods that might not be on the list. So those resources can also be found in the same place. Everything can be found@digestivehealthinstitute.org. (42:40): Awesome. Well, I invite everybody who is interested to go and check that out and get that valuable resource. Thank you so much, norm for this deep conversation, deep dive into functional gut issues and what to do about them. (42:54): Well, thank you Karen. Good questions, (42:56): And thank you all for joining me for another episode of The Hormone Prescription with Dr. Kyrin. Hopefully you've heard something here today that will be impactful for your health and your life so that you can make changes to move you towards the brilliant health that you deserve to be experiencing if you are not there yet. Stay tuned. Next week I will have another wonderful guest and episode helping you better understand your health and your body from a functional approach and how to improve it. And I'll see you again next week. Until then, peace, love, and hormones, y'all. (43:30): Thank you so much for listening. I know that incredible vitality occurs for women over 40 when we learn to speak hormone and balance these vital regulators to create the health and the life that we deserve. If you're enjoying this podcast, I'd love it if you'd give me a review and subscribe. It really does help this podcast out so much. You can visit the hormone prescription.com where we have some free gifts for you, and you can sign up to have a hormone evaluation with me on the podcast to gain clarity into your personal situation. Until next time, remember, take small steps each day to balance your hormones and watch the wonderful changes in your health that begin to unfold for you. Talk to you soon.   ► Free Fast Track Diet 101 ebook from Dr. Norm Robillard - CLICK HERE ► Hormone Balance Bliss Challenge by Dr. Kyrin Dunston Are you struggling to find the right solution to get your hormones and metabolism back in balance?   If you're feeling like nothing is working, it's time to try something else! Our Hormone Balance Bliss Challenge was designed specifically for those who are looking for a long-term way out of their hormone and energy struggles. We'll help you understand what doctors aren't telling about how hormones affect weight gain, energy levels, and overall wellbeing.   With our easy-to-follow 7 day plan, no more will you feel confused by your condition or overwhelmed about how to fight against it - we'll give you all the tools needed so that within just 7 days from now YOU can start experiencing true health bliss again! Join us today on this journey into hormone balance bliss - CLICK HERE to sign up now and get started on reclaiming your mojo!

Get a free nursing lab values cheat sheet at NURSING.com/63labs   What is the Lab Name for Amylase Lab Values? Amylase   What is Amylase in terms of Nursing Labs? Amylase is made in the pancreas. It is an enzyme that breaks down carbohydrates to allow our body to absorb it. Monitoring amylase levels can identify problems with the pancreas.   What is the Normal Range for Amylase? 0-130 U/L   What are the Indications for Amylase? Diagnosing: Pancreatitis Pancreatic Duct Obstruction Macroamylasemia Trauma to Pancreas   What would cause Increased Levels of Amylase? Pancreatitis Pancreatic Cancer Pancreatic Cyst DKA Peritonitis Abdominal Trauma Duodenal Obstruction Mumps Alcohol use   What would cause Decreased Levels of Amylase? Pancreatic Insufficiency Pancreatectomy Toxemia of Pregnancy Cystic Fibrosis Liver Disease

In diesem Interview mit Sonja Slottke erfährst Du viel Interessantes über die Ananas. Von der Entdeckung, über die Geschichten zur Namensgebung bis hin zu den gesundheitlichen Aspekten der Ananas wird Dir gezeigt, was die Ananas so wertvoll macht.

Hey friend! Thanks for coming back to another episode of our weekly Homebrew Happy Hour podcast… the home brew #podcast where we answer all of your home brewing questions and discuss anything related to craft beer! A SUBTLE REMINDER: If you appreciate the things we do here at Homebrew Happy Hour, consider joining our Trub […]

あんかけの餡が食べていると分解されてしまう問題、北米のスーパー事情、クルマで国境を超える簡単さ、おすすめの雑誌やマンガを紹介しました。Shownotes TVer かりそめ天国 月曜から夜ふかし (Wikipedia) アミラーゼ (Wikipedia) フールナイト フールナイト 白雷の騎士 男子高校生の日常 BRUTAS マガジンハウス BRUTAS 危険な読書 (Amazon) dancyu 餃子の王道 (Amazon) … 巻頭で紹介されている沼津の中央亭が今でも世界最強だとおもっています。本当にあの餃子を最初に食べた時は衝撃だった。(by tadasu) POPEYE 集英社 すばる 早稲田文学 講談社 群像 … 日本にいたころsohは群像や新潮を毎月のように買って読んでいた… SFマガジン (Wikipedia) Number あの人のノートが見たい … ノートフェチにとっては本当に最高だった。Researchat.fm のノート回も一緒にどうぞ。 将棋世界 日本将棋連盟 kotoba 生命とは何か (Amazon) …Torsten Wieselの良い研究は「対」によって行われるとか、今の研究は星を繋いで星座を作るようなもの、みたいな批判やPaul Nurseの「良い研究者はいくつかの問いを投げ掛ければすぐにわかる」みたいな念能力者の言葉みたいなのがすごいよかった笑 (by tadasu) エルフェンリート (Amazon) なるたる (Amazon) のりりん (Amazon) ぼくらの (Amazon) Editorial notes みなさんはあんかけで困っていますか？(soh) あんかけがびしゃびしゃになる人がいるの本当に目からウロコです。アスパラガス尿なみにびっくり。(tadasu) 俺のアミラーゼ力が足りないというのか…？(coela)

Blutwerte zu interpretieren ist gar nicht so einfach. Manchmal sind Blutwerte in der Norm und man fühlt sich trotzdem nicht gut. Was sagt das kleine Blutbild aus und was ist ein großes Blutbild? Warum sind meine Leberwerte erhöht, obwohl ich gar keinen Alkohol trinke. Was ist Lipase und Amylase, was bedeuten HDL und LDL. In der heutigen Folge dreht sich alles um Blutwerte. ... HIER ERFÄHRST DU MEHR: Alexandra Luczak, Dipl. Des., Achtsamkeitscoach https://kreativothek.de/ Insta: @kopffreimitalex @kreativothek.alex Alexandra Nau, Heilpraktikerin https://www.naturheilpraxis-alexandra-nau.de/ Insta: @naturheil_chiropraxis_nau

In this episode, I speak with Melanie Stegman, Assistant Professor at the Center for Advanced Entertainment and Learning Technology at Harrisburg University in Pennsylvania. Melanie was interested in biochemistry from an early age, and worked in biochemistry labs while earning an BA in political science. After college, she started writing a story about Amy the Amylase, intending to make molecular cell biology less scary for everyone. To get the biochemistry right in her stories, Melanie pursued a PhD in Molecular Genetics, Biochemistry, and Microbiology from the University of Cincinnati.  During her postdoctoral fellowship at Weill Cornell Medical College, Melanie found out about an educational video game being made by a think tank in Washington, DC. Melanie then moved to DC, won a grant to study the game, and based on her research, designed and produced a new game called Immune Defense. After 5 years of trying to get a game studio off the ground, Melanie is now a professor of interactive media and science communication. She creates games about chemistry and teaches game development, while still dabbling in indie game development. Links to resources mentioned in this episodeGame Engines:Unity 3DUnrealConstructGamemakerScratchOther links:Blender 3DItch.ioGames for ChangeScience Game CenterImmune Attack and Immune Defense video gamesInternational Game Developer AssociationGame Developer Conference

Welcome to 2022 family. In this short episode I will explain what gut enzymes are & how they relate to metabolic flexibility. Enjoy & let's crush 2022!! Shownotes are available @ https://zecohealth.com/gutenzymes/

Amylase testing has long been used as a diagnostic tool for pancreatitis, despite amylase levels not being a definitive indicator of pancreatitis. Lipase offers a more useful diagnostic result, as its readings are a better indicator of inflammation of the pancreas, according to James Nichols, PhD, a member of the CAP Quality Practices Committee. Ordering a combination of amylase and lipase is a common practice, but the combination does not increase the sensitivity over a single test. Likewise, serial testing of lipase does not offer better monitoring or treatment. As part of the CAP Test Ordering Program, a new module (https://capatholo.gy/3Du78fr) provides information and resources for the pathologist to address unnecessary testing volumes in the laboratory while still providing effective patient care, as Dr. Nichols explains in this CAPcast.

Bigger is Better - The Suzanne Somers Podcast On this episode of The Suzanne Somers Podcast Suzanne reveals the new VALUE SIZE bag of her amazing GUT RENEW Superfood Protein Formula. Find out why everyone is talking about Suzanne's best-selling new product with organic, plant-based protein, gut health nutrients, immune support and more! With so many people experiencing digestive and stomach issues, Suzanne explains the importance of probiotics, prebiotics, and digestive enzymes to turn around gut health. NO MORE BLOATING! GUT RENEW contains 20 grams or organic, plant-based protein, ZERO sugars and only 3 grams of carbs. Plus, it's delicious! She and Alan enjoy a Chocolate Peanut Butter Banana smoothie that looks like a milkshake! Go to SuzanneSomers.com for GUT RENEW Superfood Protein Formula (Value Size 30-Servings!) ONLY $99.99 at SuzanneSomers.com SUZANNE™ GUT RENEW (VALUE SIZE) Superfood Protein Formula Organic Plant-Based Protein and Gut Health Support With Phyto Greens • Phyto Fruit and Vegetable Blend • Sea Minerals Each serving Includes 20 grams of protein, ZERO grams of sugar, and 3 grams of carbs! Support the critical balance of the gut with this powerhouse blend of the highest quality plant-based proteins loaded with superfoods from phyto greens, fruits and vegetables, plus the most important nutrients to support gut health.    Add to your favorite smoothie for a superfood protein burst 4 ORGANIC PLANT-BASED PROTEINS Sprouted Fermented Pea Protein • Sprouted Fermented Rice Protein Hemp Protein • Sacha Inchi Protein 5 PHYTO GREENS Chlorella • Spirulina • Young Alfafa Sprouts • Barley Grass • Wheatgrass 5 GUT HEALTH NUTRIENTS Digestive Enyzmes • Probiotic Fermented Blend • Prebiotic Jerusalem Artichoke • Triphala Blend • Marshmallow Extract Powder 5 IMMUNE SUPPORT BOOSTERS Ginger • Turmeric • Sea Buckthorn • Ceylon Cinnamon • Shiitake Mushroom 8 PHYTO FRUITS & VEGETABLES BLEND Beetroot • Carrot • Kale • Spinach • Acai • Apple • Grape • Broccoli Sprout 50+ SEA MINERALS Trace Levels of over 50 Minerals including Magnesium & Zinc ORGANIC SWEETENER Organic Stevia Leaf Extract   SERVING SUGGESTIONS: Place 2 tablespoons SUZANNE GUT RENEW + 8 oz. Coconut Milk + 1/2 cup Blueberries + Ice into blender and blend until smooth.  INGREDIENTS: Organic Sprouted Fermented Pea Protein, Organic Sprouted Brown Rice Protein, Organic Hemp Protein, Organic Sachs Inchi Protein, Organic Ceylon Cinnamon Powder, Natural Vanilla Flavor, Organic Jerusalem Artichoke Inulin Powder, Marshmallow Root Extract Powder, Aquamin. (Sea Mineral Complex Algae Powder), Organic Sea Buckthorn Juice Powder•, organic pmanthus Emblica, Organic Terminals Chebula, Organic Terminals Emblica, Organic Stevia Leaf Extract Powder, Organic Spirulina Powder, Organic Chlorella Powder, Organic Alfalfa Grass Powder, Organic Barley Grass Powder, Organic Wheatgra. Powder, Organic Ferment. Powder (Mung Bean, Brown Rice, Red Lentil, Chick Pea, Flaxseed, Millet & Quinoa)• Organic Ginger Root Powder, Organic Turmeric Root Powder, Organic D2 Shiitake Mushroom Powder, Protease, Organic Carrot Powder, Organic Beetroot Powder, Organic Kale Powder, Organic Spinach Powde•+, Organic Acai Juice Powder, Amylase, Lipase, Organic Apple Powder, Organic Grape Juice Powder, Organic Broccoli Sprout Powder, Lactase, Cellulase. US Certified Organic Australian Certified Organic + European Organic Certified  #SuzanneSomers #SUZANNEOrganics #SUZANNESelects Get the book A New Way To Age by Suzanne Somers in paperback at https://www.suzannesomers.com/products/a-new-way-to-age-paperback-book Find out what Suzanne is up to and go to SuzanneSomers.com for more info on all of her incredible products. Suzanne Somers is one of America's most popular and beloved personalities. In a multifaceted career that has spanned more than three decades, she has achieved extraordinary success as an actress, singer, comedienne, New York Times bestselling author, Las Vegas Entertainer of the Year, entrepreneur, and lecturer. She is the voice and face of alternative medicine. She received an Emmy nomination as Outstanding Host for “The SUZANNE Show,” her weekly Lifetime Network talk show, which provides a thought-provoking morning show alternative with in-depth information on health and wellness in a casual, entertaining format. Suzanne's fun, smart, empowering talk show, “Suzanne Somers' Breaking Through,” airs online on the CafeMom Studios YouTube channel. For Healthy, Clean Living Suzanne Somers has developed beauty and health products that are pure and clean, easy and fun! Suzanne Somers beauty products are made with natural botanical extracts, enzymes, skin-nurturing anti-oxidants, organic fruits, and vegetables. From nourishing skin-care to flawless make-up, these products were designed to help you glow. For an in-home fitness experience, Suzanne Somers delivers products for amazing results. Her simple, achievable guidelines for exercising and eating right help you look and feel better. With her products and fitness plans, you'll be eating right and looking great while committing to a healthier lifestyle! Be beautiful inside and out with Suzanne Somers Beauty, Health & Fitness! Find The Suzanne Somers Podcast - On YouTube, Facebook, Instagram, Apple Podcasts, Google Podcasts, Spotify, and everywhere great podcasts are found.

Le but de cet épisode est de vous aider à comprendre les différentes transformations d'un aliment, de l'entrée à la sortie du tube digestif.  Bonne écoute

Additional Resources:Colic Webinar with Presentation Notes - https://standleeforage.com/nutrition/nutritional-webinars/decrease-colicColic Nutritional White Paper - https://standleeforage.com/nutrition/nutritional-papers/decrease-your-horses-risk-of-colic-with-nutrition-managementYouth/Beginner Webinar on Intro to Horse Digestion with Presentation Notes - https://standleeforage.com/nutrition/nutritional-webinars/introduction-to-horse-digestionHorse's Digestive System Webinar with Presentation Notes - https://standleeforage.com/nutrition/nutritional-webinars/window-into-your-horses-digestive-system____________________________________Have a topic idea or feedback to share? We want to connect with you! Email podcast@standleeforage.comShare our podcast and learn more about our co-hosts at our Beyond the Barn podcast pageSUBSCRIBE to the Beyond the Barn podcast email to be an exclusive insider!Find us on Apple, Spotify or Google Podcasts and SUBSCRIBE, so you never miss an episode.____________________________________Check out the Standlee Barn Bulletin BlogFind more nutritional resources from Dr. Stephen Duren and Dr. Tania Cubitt at https://standleeforage.com/nutrition/nutritional-resourcesConnect with Standlee on Facebook, Instagram, YouTube and TikTok

Here’s why eating garlic and onions can prevent hypertension and diabetes Federal University of Technology (Nigeria), April 16, 2021 n a recent study, researchers at the Federal University of Technology in Nigeria investigated the benefits of eating garlic, white onion and purple onion against serious conditions like diabetes and hypertension. They confirmed these by looking at how extracts from the three alliums affect the activity of diabetes-related enzymes, such as a-amylase and a-glucosidase, and the hypertension-related enzyme, angiotensin-converting enzyme (ACE). The researchers reported their findings in an article published in the Journal of Dietary Supplements. Garlic, white onion and purple onion show antioxidant, antidiabetic and antihypertensive properties Garlic and onions are spices commonly used in cooking. They also serve as ingredients in several traditional delicacies in Nigeria that are known to contain plenty of polyphenols. To assess the beneficial properties of garlic, white onion and purple onion, the researchers first obtained extracts from each and assessed their inhibitory effects on certain enzymes. They also conducted assays to determine the antioxidant capacities of the extracts. ACE is the enzyme responsible for converting angiotensin I into angiotensin II, the hormone that increases blood pressure, as well as body water and sodium content. Angiotensin II elevates blood pressure by constricting the blood vessels; hence, chemicals that can inhibit the activity of ACE, which is responsible for the production of angiotensin II, are used for the treatment of hypertension. (Related: Meet the “two-day cure” plant: An African medicinal plant that can naturally lower blood pressure.) a-Amylase is the enzyme that breaks down starch and glycogen into glucose and maltose (two glucose molecules bound together). In humans, this enzyme is produced by the salivary glands and the pancreas. a-Glucosidase, on the other hand, is responsible for breaking down carbohydrates in the small intestine and facilitating the absorption of glucose. Inhibiting the activity of this enzyme is one of the strategies currently used to prevent the rise of blood sugar levels following a carbohydrate-filled meal. The researchers reported that the garlic, purple onion and white onion extracts inhibited the activities of ACE, a-amylase and a-glucosidase in vitro in a concentration-dependent manner. At a half maximal inhibitory concentration (IC50) of 0.59 mg/mL, the purple onion extract exhibited a higher inhibitory effect on ACE than the white onion extract (IC50 = 0.66 mg/mL) and the garlic (IC50 = 0.96 mg/mL) extract. Meanwhile, the white onion extract showed a significantly stronger inhibitory effect on a-amylase at an IC50 of 3.93 mg/mL than the garlic extract (IC50 = 8.19 mg/mL) and the purple onion (IC50 = 8.27 mg/mL) extract. The garlic extract, on the other hand, showed a similar inhibitory effect (IC50 = 4.50 mg/mL) on a-glucosidase as the white and purple onion extracts. All three extracts also showed dose-dependent free radical scavenging activity and reducing power in the antioxidant assays. Based on these findings, the researchers concluded that garlic, white onion and purple onion can be used to treat or prevent diabetes and hypertension, thanks to their ability to inhibit ACE, a-amylase and a-glucosidase activity, as well as lipid peroxidation in the pancreas and the heart.   Adolescents with lack of empathy show early signs of psychopathy   University of Coimbra (Portugal), April 14, 2021 A pioneering study with the Portuguese population shows that adolescents with high levels of callous-unemotional traits demonstrate lower levels of anticipated guilt towards the possibility of committing an immoral act and struggle to judge an immoral act as a wrong one. Researchers have evaluated the callous traits, that is, the lack of empathy and disregard for the wellbeing and feelings of others, of 47 adolescents between 15 and 18 years old. The teenagers watched video animations portraying examples of moral transgressions, such as incriminating someone or keeping money that fell from someone else's pocket. "This approach allowed us to create more realistic scenarios that happen in daily life," explains Oscar Gonçalves, a neuroscientist at Proaction Lab and co-author of the study. The adolescents were asked how guilty they would feel if they were the ones to commit the moral transgressions and how wrong they think the actions were.  Although the callous-unemotional traits in adolescents are known to be precursors of psychopathy in adulthood, the results of the study differ from what is known about psychopaths. "Adults with psychopathic traits show low levels of anticipated guilt but consider immoral actions as wrong. However, in our study, adolescents with high CU levels show levels of guilt and judge immoral actions as less wrong," explains Margarida Vasconcelos, first author.  However, researchers have found evidence of a dissociation between moral emotions and moral judgment, that is, between the feelings of guilt and the judgment of immoral actions. "Even in adolescents with sub-clinical levels of callous-unemotional traits, this dissociation typical in psychopathy in adulthood is already happening during development," explains the study coordinator Ana Seara Cardoso.  The results of the study will "contribute to the development of a severe anti-social behavior model" and allow the "development of intervention targets, rehabilitation and early prevention of anti-social behavior," says Ana Seara Cardoso.   Omega-3 supplements do double duty in protecting against stress   Ohio State University, April 20, 2021 A high daily dose of an omega-3 supplement may help slow the effects of aging by suppressing damage and boosting protection at the cellular level during and after a stressful event, new research suggests. Researchers at The Ohio State University found that daily supplements that contained 2.5 grams of omega-3 polyunsaturated fatty acids, the highest dose tested, were the best at helping the body resist the damaging effects of stress. Compared to the placebo group, participants taking omega-3 supplements produced less of the stress hormone cortisol and lower levels of a pro-inflammatory protein during a stressful event in the lab. And while levels of protective compounds sharply declined in the placebo group after the stressor, there were no such decreases detected in people taking omega-3s. The supplements contributed to what the researchers call stress resilience: reduction of harm during stress and, after acute stress, sustained anti-inflammatory activity and protection of cell components that shrink as a consequence of aging. The potential anti-aging effects were considered particularly striking because they occurred in people who were healthy but also sedentary, overweight and middle-aged—all characteristics that could lead to a higher risk for accelerated aging. "The findings suggest that omega-3 supplementation is one relatively simple change people could make that could have a positive effect at breaking the chain between stress and negative health effects," said Annelise Madison, lead author of the paper and a graduate student in clinical psychology at Ohio State. The research is published today (Monday, April 19, 2021) in the journal Molecular Psychiatry. Madison works in the lab of Janice Kiecolt-Glaser, professor of psychiatry and psychology and director of the Institute for Behavioral Medicine Research at Ohio State. This paper is a secondary analysis of one of Kiecolt-Glaser's earlier studies showing that omega-3 supplements altered a ratio of fatty acid consumption in a way that helped preserve tiny segments of DNA in white blood cells. Those short fragments of DNA are called telomeres, which function as protective caps at the end of chromosomes. Telomeres' tendency to shorten in many types of cells is associated with age-related diseases, especially heart disease, and early mortality. In the initial study, researchers were monitoring changes to telomere length in white blood cells known as lymphocytes. For this new study, the researchers looked at how sudden stress affected a group of biological markers that included telomerase, an enzyme that rebuilds telomeres, because levels of the enzyme would react more quickly to stress than the length of telomeres themselves. Specifically, they compared how moderate and high doses of omega-3s and a placebo influenced those markers during and after an experimental stressor. Study participants took either 2.5 grams or 1.25 grams of omega-3s each day, or a placebo containing a mix of oils representing a typical American's daily intake. After four months on the supplements, the 138 research participants, age 40-85, took a 20-minute test combining a speech and a math subtraction task that is known to reliably produce an inflammatory stress response. Only the highest dose of omega-3s helped suppress damage during the stressful event when compared to the placebo group, lowering cortisol and a pro-inflammatory protein by an average of 19% and 33%, respectively. Results from blood samples showed that both doses of omega-3s prevented any changes in telomerase levels or a protein that reduces inflammation in the two hours after participants experienced the acute stress, meaning any needed stress-related cell repair—including telomere restoration—could be performed as usual. In the placebo group, those repair mechanisms lost ground: Telomerase dropped by an average of 24% and the anti-inflammatory protein decreased by an average of at least 20%. "You could consider an increase in cortisol and inflammation potential factors that would erode telomere length," Madison said. "The assumption based on past work is that telomerase can help rebuild telomere length, and you want to have enough telomerase present to compensate for any stress-related damage. "The fact that our results were dose-dependent, and we're seeing more impact with the higher omega-3 dose, would suggest that this supports a causal relationship." The researchers also suggested that by lowering stress-related inflammation, omega-3s may help disrupt the connection between repeated stress and depressive symptoms. Previous research has suggested that people with a higher inflammatory reaction to a stressor in the lab may develop more depressive symptoms over time. "Not everyone who is depressed has heightened inflammation—about a third do. This helps explain why omega-3 supplementation doesn't always result in reduced depressive symptoms," Kiecolt-Glaser said. "If you don't have heightened inflammation, then omega-3s may not be particularly helpful. But for people with depression who do, our results suggest omega-3s would be more useful." The 2.5-gram dose of omega-3s is much higher than what most Americans consume on a daily basis, but study participants showed no signs of having problems with the supplements, Madison said.           Want to be robust at 40-plus? Meeting minimum exercise guidelines won't cut it 5 hours of moderate activity a week may be required to avoid midlife hypertension, UCSF-led study shows University of California at San Francisco, April 15, 2021 Young adults must step up their exercise routines to reduce their chances of developing high blood pressure or hypertension - a condition that may lead to heart attack and stroke, as well as dementia in later life. Current guidelines indicate that adults should have a minimum of two-and-a-half hours of moderate intensity exercise each week, but a new study led by UCSF Benioff Children's Hospitals reveals that boosting exercise to as much as five hours a week may protect against hypertension in midlife - particularly if it is sustained in one's thirties, forties and fifties.  In the study publishing in American Journal of Preventive Medicine on April 15, researchers followed approximately 5,000 adults ages 18 to 30 for 30 years. The participants were asked about their exercise habits, medical history, smoking status and alcohol use. Blood pressure and weight were monitored, together with cholesterol and triglycerides.  Hypertension was noted if blood pressure was 130 over 80 mmHg, the threshold established in 2017 by the American College of Cardiology/American Heart Association.  The 5,115 participants had been enrolled by the Coronary Artery Risk Development in Young Adults (CARDIA) study and came from urban sites in Birmingham, Ala., Chicago, Minneapolis and Oakland, Calif. Approximately half the participants were Black (51.6 percent) and the remainder were White. Just under half (45.5 percent) were men.  Fitness Levels Fall Fast for Black Men Leading to More Hypertension Among the four groups, who were categorized by race and gender, Black men were found to be the most active in early adulthood, exercising slightly more than White men and significantly more than Black women and White women. But by the time Black men reached age 60, exercise intake had slumped from a peak of approximately 560 exercise units to around 300 units, the equivalent to the minimum of two-and-a-half hours a week of moderate intensity exercise recommended by the U.S. Department of Health and Human Services. This was substantially less exercise than White men (approximately 430 units) and slightly more than White women (approximately 320 units). Of the four groups, Black women had the least exercise throughout the study period and saw declines over time to approximately 200 units. "Although Black male youth may have high engagement in sports, socio-economic factors, neighborhood environments, and work or family responsibilities may prevent continued engagement in physical activity through adulthood," said first author Jason Nagata, MD, of the UCSF Division of Adolescent and Young Adult Medicine. Additionally, Black men reported the highest rates of smoking, which may preclude physical activity over time, he noted. Physical activity for White men declined in their twenties and thirties and stabilized at around age 40. For White women, physical activity hovered around 380 exercise units, dipping in their thirties and remaining constant to age 60. Rates of hypertension mirrored this declining physical activity. Approximately 80-to-90 percent of Black men and women had hypertension by age 60, compared with just below 70 percent for White men and 50 percent for White women.  "Results from randomized controlled trials and observational studies have shown that exercise lowers blood pressure, suggesting that it may be important to focus on exercise as a way to lower blood pressure in all adults as they approach middle age," said senior author Kirsten Bibbins-Domingo, MD, PhD, of the UCSF Department of Epidemiology and Biostatistics.  "Teenagers and those in their early twenties may be physically active but these patterns change with age. Our study suggests that maintaining physical activity during young adulthood - at higher levels than previously recommended - may be particularly important." More Exercise from Youth to Midlife Offers Best Protection Against Hypertension When researchers looked at the 17.9 percent of participants who had moderate exercise for at least five hours a week during early adulthood - double the recommended minimum - they found that the likelihood of developing hypertension was 18 percent lower than for those who exercised less than five hours a week. The likelihood was even lower for the 11.7 percent of participants who maintained their exercise habits until age 60.  Patients should be asked about physical activity in the same way as they are routinely checked for blood pressure, glucose and lipid profiles, obesity and smoking, Nagata said, and intervention programs should be held at schools, colleges, churches, workplaces and community organizations. Black women have high rates of obesity and smoking, and low rates of physical activity, he said, and should be an important group for targeted intervention.  "Nearly half of our participants in young adulthood had suboptimal levels of physical activity, which was significantly associated with the onset of hypertension, indicating that we need to raise the minimum standard for physical activity," Nagata said. "This might be especially the case after high school when opportunities for physical activity diminish as young adults transition to college, the workforce and parenthood, and leisure time is eroded."     Study finds association between periodontal disease and low intake of minerals, vitamins and dietary fiber in young adult women Tokyo Medical and Dental University, April 12, 2021 According to news reporting out of Tokyo, Japan, research stated, “Dietary habits of middle-aged and elderly individuals affected by periodontal disease (PD) differ from those who are unaffected by it, according to previous reports. However, in young adults, there are only a few reports that show a correlation between nutrient/food intake and PD.” Our news journalists obtained a quote from the research from Tokyo Medical and Dental University (TMDU), “Moreover, no report till date has assessed the correlation between dietary habits and PD using a self-administered diet history questionnaire (DHQ). Therefore, we assessed this correlation using a DHQ in young adult women who are likely to develop PD. The participants were enrolled from 2 universities and included 120 female college students a mean age of 20.4 y. The participants were assessed for the presence of PD according to the community periodontal index and were divided into two groups, the PD group and the non-PD group. Their dietary habits were investigated using a DHQ and the level of difficulty in chewing food was assessed. The PD group had a significantly lower nutrient intake of minerals, fat-soluble vitamins, water-soluble vitamins, and dietary fiber than the non-PD group. In terms of food groups, the PD group consumed significantly lesser amounts of green and yellow vegetables (GYV) than the non-PD group. Multivariate analysis revealed that the PD group had significantly lower intakes of vitamin E and GYV than the non-PD group. The PD group consumed significantly lesser amounts of hard foods than the non-PD group.” According to the news editors, the research concluded: “Young adult women who were evaluated for PD by a screening test had a significantly lower nutrient/food intake than those without a PD.” This research has been peer-reviewed.       Just 2 days of increased sugar intake can harm your gut health, warn researchers University of Alberta, April 16, 2021 Researchers from the University of Alberta in Canada found that short-term increases in sugar intake can increase the risk of inflammatory bowel disease. Their finding, which was published in Scientific Reports, is a reminder that eating healthy must be sustained in order to keep your gut in good shape. “Surprisingly, our study shows that short-term sugar consumption can really have a detrimental impact, and so this idea that it’s OK to eat well all week and indulge in junk food on the weekend is flawed,” said Karen Madsen, one of the study researchers. Increased sugar intake is bad for the gut Previous studies have shown that diets can affect your susceptibility to disease. Western diets, for example, have been implicated in the development of inflammatory bowel disease. But it’s still unclear when a poor diet begins to take a toll on your health, much less how it does so. To investigate, the researchers placed adult mice on a chow diet or a high-sugar diet and treated them with dextran sodium sulfate to induce ulcerative colitis, one of the major forms of inflammatory bowel disease. Disease severity was assessed daily. After two days, the mice on the high-sugar diet were at great risk of developing colitis. Their immune response also weakened while their gut permeability increased, allowing more bacteria and toxins to enter their bloodstream. “We wanted to know how long it takes before a change in diet translates into an impact on health. In the case of sugar and colitis, it only took two days, which was really surprising to us. We didn’t think it would happen so quickly,” said Madsen. The researchers attributed these effects to sugar’s impact on the gut bacteria. Eating sugary foods decreases the amount of “good” gut bacteria that produce short-chain fatty acids, which are critical for a strong immune response. Meanwhile, sugar feeds “bad” bacteria that promote inflammation and weaken your immunity.  Fortunately, the researchers found that supplementing with short-chain fatty acids helped reduce the negative effects of a high-sugar diet. Having these supplements as an option will be great for people struggling to change their bad eating habits. “People want to eat what they want to eat, so short-chain fatty acids could possibly be used as supplements to help protect people against the detrimental effects of sugar on inflammatory bowel disease,” said Madsen.     Rose water is an antimicrobial and anti-inflammatory remedy for skin infections Teikyo University (Japan), April 15, 2021 Rosa damascena, commonly known as Damask rose, is one of the most important and medicinally useful members of the Rosaceae (rose) family. It is an ornamental plant widely used to make perfumes and is reported to have plenty of beneficial properties. According to multiple studies, Damask rose has anti-HIV, antibacterial, antioxidant, antitussive, hypnotic and antidiabetic properties. It has also shown relaxant effects on the tracheal chains of guinea pigs. In a recent study, researchers at Teikyo University in Japan investigated two biological properties of Damask rose, specifically it’s antimicrobial and anti-inflammatory properties. They tested rose water made from high-quality Damask rose petals on two microbial pathogens, namely, Candida albicans and methicillin-resistant Staphylococcus aureus (MRSA), which commonly cause skin infections. The researchers reported their findings in an article published in Biological and Pharmaceutical Bulletin. Damask rose water is a natural antibiotic and anti-inflammatory agent Damask rose is a multipurpose plant widely known for its culinary and medicinal applications, among other things. Edible parts of Damask rose are used in various cuisines, including its young shoots, petals, fruits, leaves and seeds. Damask rose petals are used to make jams and add flavor to beverages, baked goods and desserts. They are also used for cooking dishes. Rosewater, which can be sweetened to produce rose syrup, is a byproduct of rose oil production. It is usually obtained by steam distilling Damask rose petals and taking the hydrosol portion of the rose petal distillate.  In different parts of the world, rose water, rose oil and a decoction made of Damask rose roots are used in traditional medicine for the treatment of various ailments, such as abdominal and chest pain, digestive problems and inflammation, especially of the neck. In North America, Indian tribes use the decoction as a cough remedy for children. Rose oil is used to treat depression and reduce stress and tension. Inhaling the vapor produced by heating rose oil is also believed to be an effective remedy for allergies, headaches and migraine. Damask rose water, on the other hand, is traditionally used to treat skin conditions, such as erythema (skin redness), itchiness and swelling. To evaluate its antimicrobial and anti-inflammatory properties, the researchers tested Damask rose water against C. albicans and MRSA and assessed its effects on the function of neutrophils, which are white blood cells that serve as key regulators of inflammatory reactions. The researchers reported that Damask rose water (2.2. percent solution) inhibited the mycelial growth of C. albicans and reduced the viability of MRSA within an hour of treatment. Damask rose water (five to 15 percent) also suppressed the activation of neutrophils induced by treatment with lipopolysaccharide (LPS), a bacterial toxin; tumor necrosis factor-alpha (TNF-a), a cell-signaling protein produced by immune cells; and N-formyl-Met-Leu-Phe (fMLP), a macrophage activator. Additionally, Damask rose water reduced LPS- and TNF-a-induced cell surface expression of the adhesion-related molecule, cluster of differentiation 11b (CD11b), which is rapidly elevated by the activation of neutrophils. The amount of CD11b in neutrophils is said to correlate with their activation and inflammation. However, Damask rose water did not affect the migratory capacity of neutrophils (with or without a chemoattractant). Based on these findings, the researchers concluded that Damask rose water can reduce the pathogenicity of microbes and attenuate neutrophil stimulation, thus inhibiting skin inflammation caused by microbial infections.     Study shows how chronic stress may inhibit the body's cancer-fighting ability University of Western Ontario, April 15, 2021 New research from Western University has shown how psychological stress hinders the immune system's defenses against cancer. By investigating the effects of chronic stresson the immune system's "emergency responders," researchers at the Schulich School of Medicine & Dentistry found that a stress-induced hormone impairs the ability of these immune cells to carry out their cancer-fighting function. Led by Mansour Haeryfar, Ph.D., the research looked specifically at innate-like T cells, which when functioning properly enable the immune system to look for potentially cancerous cells in the body and destroy them. The study was published today in Cell Reports. Innate-like T cells include invariant natural killer T (iNKT) and mucosa-associated invariant T (MAIT) cells, which were the subjects of this investigation. iNKT cells are present in small numbers in many tissues but are especially enriched in the human omentum, an apron-like layer of fatty tissue. MAIT cells are present in relatively high numbers in the human peripheral blood, gut, lungs and liver among other organs. "These innate-like T cells are our immune system's emergency responders," said Haeryfar. "They react quickly to pathogens and cancer cells and are in a pre-activated mode, so they are like loaded guns, ready to respond." Previous studies have shown that when a person experiences chronic psychological and emotional stress, the body's immune system is suppressed, dampening its ability to fight cancer and opportunistic infections. This happens in large part because stress hormones kill off some of the body's immune cells. However, Haeryfar and his team showed that innate-like T cells actually don't die as a result of chronic stress but their cancer-fighting abilities are drastically impaired by stress-induced hormones called glucocorticoids. This impairment led to a striking increase in cancer metastasis in a mouse model. "We found that innate-like T cells survive when the host is under stress, but their functions are compromised," Haeryfar said. "The cells cannot make enough of their beneficial mediators to help fight cancer, so the metastatic burden is increased because of the stress." The team also looked at the effects of natural and synthetic glucocorticoids on innate-like T cells in human blood and liver tissue, where they are abundant. This was important to providing initial evidence that some of the discoveries made in the mouse models were valid for human cells as well, said Patrick Rudak, Ph.D. Candidate in Haeryfar's lab. One of the important implications of this work is that innate-like T cells are currently being investigated for cancer immunotherapy treatment. This study demonstrates that their therapeutic potential can be dampened by psychological stress, said Haeryfar, and this finding needs to be considered when designing or administering those therapies. Rudak added: "Our study demonstrates that, despite being capable of instigating robust anti-tumor immune responses under normal conditions, innate-like T cells completely fail to protect against tumors during psychological stress." Because the study also uncovered the mechanisms by which stress diminishes T cell function, the researchers hope they can use the information to help design immunotherapies involving these cells that will still be effective in psychologically stressed patients.

  Blueberries protect against inflammation Texas Women's University, March 14, 2021   In a recent study, researchers at Texas Woman’s University investigated the usefulness of polyphenols present in blueberries in controlling or reducing inflammation. Induced by oxidative stress, inflammation — especially if it becomes persistent — is closely linked to the development of many chronic diseases, such as diabetes, metabolic syndrome, inflammatory bowel disease and rheumatoid arthritis (RA). The researchers discussed the anti-inflammatory activities of BBPs in an article published in the Journal of Medicinal Food. Blueberry polyphenols can be used for the treatment of rheumatoid arthritis RA is an autoimmune and chronic inflammatory disease that destroys joints and causes disability in older adults. The etiology of RA is poorly understood and there is no mainstream cure for this disease. According to research, the accumulation and proliferation of fibroblast-like synoviocytes — non-immune cells that make up the membranous tissue that lines joint cavities — may be involved in the destruction of cartilage commonly observed in RA. On the other hand, in vivo and in vitro studies suggest that the anti-inflammatory properties of dietary polyphenols derived from fruits and vegetables could help prevent this destruction. To examine the anti-inflammatory activities of blueberry polyphenols against RA, the researchers first stimulated rabbit synoviocytes with tumor necrosis factor alpha (TNF-a), a cell signaling protein (cytokine) released by immune cells that plays a huge role in systemic inflammation. They then treated the synoviocytes with different doses of blueberry polyphenols. The researchers found that the pro-inflammatory cytokine, TNF-a, increased synoviocyte proliferation by around 19 percent, but treatment with blueberry polyphenols significantly decreased proliferation in a dose-dependent manner. The polyphenol-treated synoviocytes also showed decreased levels of interleukin (IL)-1B and nuclear factor-kappa B (NF-kB). IL-1B is a cytokine required for activating the innate immune response. Its role is to mediate the release of other pro-inflammatory cytokines, especially in the presence of an infection. NF-kB, on the other hand, is a transcription factor that regulates the expression of genes involved in inflammation.  The researchers also reported that that the expression of matrix metalloproteinase 3, a key enzyme involved in the pathogenesis of RA, increased fivefold in the control TNF-a-stimulated group but decreased by threefold in the blueberry polyphenol-treated group, clearly showing the anti-RA activities of blueberry’s active components. Based on these findings, the researchers concluded that blueberry polyphenols can reduce inflammation associated with RA by downregulating the expression of pro-inflammatory cytokines and the transcription factor, NF-kB.     Relationship between vitamin D deficiency and gestational and postpartum depression Federal University of Rio de Janeiro (Brazil), March 16, 2021 According to news originating from Rio de Janeiro, Brazil, research stated, “Vitamin D deficiency (VDD) has been associated with depressive symptoms in pregnancy and postpartum, which can result in increased adverse outcomes in the maternal-infant segment. A possible explanation in the literature is VDD relationship with genetic and neurological mechanisms.” Our news journalists obtained a quote from the research from Federal University Rio de Janeiro, “to evaluate VDD relationship with gestational and postpartum depression. this review followed the recommendations proposed by the Preferred Reporting Items for Systematic Reviews and Meta-Analysis. Research was conducted in electronic databases, PubMed and LILACS, including studies of the analytical type (cross-sectional and longitudinal), systematic reviews, meta-analyses, and controlled clinical trials carried out in humans; inclusion and exclusion criteria were applied. in this systematic review, eight articles were analyzed comprising 8,583 women from seven different countries. Among the selected articles, six found an association between VDD and gestational and postpartum depression. Considering the data collection, it was possible to conclude that there is a probable relationship between VDD and a higher predisposition to gestational and postpartum depression.” According to the news editors, the research concluded: “Also, we concluded that vitamin D supplementation has proven to be a promising strategy for reducing the risk of depressive symptoms.”     Lifestyle intervention is beneficial for most people with type 2 diabetes, but not all Wake Forest Medical Center, March 11, 2021 For people who are overweight or obese and have type 2 diabetes, the first line of treatment is usually lifestyle intervention, including weight loss and increased physical activity. While this approach has cardiovascular benefit for many, it can be detrimental for people who have poor blood sugar control, according to a study conducted by researchers at Wake Forest School of Medicine. In the study, published in the current issue of the journal Diabetes Care, the researchers re-evaluated the National Institutes of Health Action for Health in Diabetes (Look AHEAD) study that found intensive lifestyle intervention (ILI) neither helped nor hurt people with diabetes.  "Contrary to the initial findings of Look AHEAD, our work found that lifestyle interventions reduced potential cardiovascular harm and optimized benefits for 85% of those in the trial," said the study's lead investigator, Michael P. Bancks, Ph.D., assistant professor of public health sciences at Wake Forest School of Medicine, part of Wake Forest Baptist Health. "However, for those who had poor blood sugar control, lifestyle intervention increased the risk of major cardiovascular events. Based on our findings, doctors may want to consider alternative options, such as glucose-lowering drugs, before trying lifestyle modification for those people."  Look AHEAD randomized 5145 participants with type 2 diabetes (T2D) who were overweight or obese to 10 years of ILI or a control group that received diabetes support and education. ILI focused on weight loss through decreased caloric intake and increased physical activity.  In the Wake Forest School of Medicine study, the researchers divided the study participants into four subgroups: diabetes onset at older age, poor glycemic control, severe obesity and younger age at onset. These subgroups were determined based on diabetes diagnosis, body mass index, waist circumference, measure of blood sugar value (glycemic control) and the age of diabetes onset.  Bancks and his team examined each group's response to the intensive lifestyle intervention and its association with major cardiovascular events. In the subgroup with poor glycemic control, the intervention was associated with 85% higher risk of having a cardiovascular event as compared to the control group. Among the three other diabetes subgroups analyzed, ILI was not associated with an increased risk of fatal and non-fatal cardiovascular events. "Although the interest in diabetes subgroups is growing, our study is one of the first to apply it to lifestyle intervention," Bancks said. "So for clinicians, determining which subgroup their patient most closely resembles should help them determine the best treatment option and reduce any potential harm for that individual."  These results provide support for further investigation into whether these findings apply to other diabetes complications, including cognitive issues, and to assess what interventions would be beneficial for those individuals, Bancks said.   Depression doubles risk of death after heart attack, angina Intermountain Medical Center Heart Institute, March 8, 2021    Depression is the strongest predictor of death in the first decade following a diagnosis of coronary heart disease, according to a study scheduled for presentation at the American College of Cardiology's 66th Annual Scientific Session. The study found people with coronary heart disease who are diagnosed with depression are about twice as likely to die compared with those who are not diagnosed with depression.   "This study shows that it doesn't matter if depression emerges in the short term or a few years down the road—it's a risk factor that continually needs to be assessed," said Heidi May, PhD, a cardiovascular epidemiologist at the Intermountain Medical Center Heart Institute in Salt Lake City and the study's lead author. "I think the take-home message is that patients with coronary disease need to be continuously screened for depression, and if found to be depressed, they need to receive adequate treatment and continued follow-up."   The study focused on patients diagnosed with a heart attack, stable angina or unstable angina, all of which are caused by a reduced flow of oxygen-rich blood to the heart, typically as a result of plaque buildup in the heart's arteries. These conditions fall under the umbrella term coronary heart disease, which is the most common form of heart disease in the United States .   Researchers have long understood heart disease and depression to have a two-way relationship, with depression increasing the likelihood of heart disease and vice versa. Whereas previous studies have investigated depression occurring within a few months of a coronary heart disease diagnosis, the new study is the first to shed light on the effects of depression over the long term.   The researchers analyzed health records from almost 25,000 Intermountain Health System patients tracked for an average of nearly 10 years following a diagnosis of coronary heart disease. About 15 percent of patients received a follow-up diagnosis of depression, a substantially larger proportion than the estimated rate of 7.5 to 10 percent in the general population.   Out of 3,646 people with a follow-up diagnosis of depression, half died during the study period, compared to 38 percent of the 20,491 people who did not have a depression diagnosis. This means people with depression were twice as likely to die compared to those without depression.   After adjusting for age, gender, risk factors, other diseases, heart attack or chest pain, medications and follow-up complications, the results showed depression was the strongest predictor of death in this patient group. These results were consistent regardless of age, gender, the timing of depression onset, past history of depression or whether or not the patient had a heart attack.   Given the significant impact of depression on long-term survival, the researchers said clinicians should seek ways to better identify depression in patients with coronary heart disease, either by using patient questionnaires designed to screen for depression or by actively watching for signs of depression during follow-up examinations.   "It can be devastating to be diagnosed with coronary artery disease," May said. "Clinicians need to pay attention to the things their patients are expressing, in terms of both physical symptoms as well as emotional and nonverbal factors."   Signs of depression include persistent feelings of sadness, hopelessness or worthlessness; anxiety, irritability or restlessness; losing interest in hobbies and activities; fatigue or moving slowly; difficulty sleeping or concentrating; aches or pains without a clear physical cause; changes in appetite or weight; and thoughts of death or suicide. Depression is linked with behaviors that can be detrimental to cardiovascular health, such as reduced physical activity, poor diet, increased smoking or alcohol use and reduced compliance with medical treatment.   The study did not evaluate the impact of depression treatment on the risk of death.     Wild mint can prevent blood sugar spikes after meals, reports study National Chemical Laboratory (India), March 12, 2021 Mentha arvensis, commonly known as wild mint, is a perennial flowering plant.  Wild mint leaves and essential oil are also traditionally used as natural medicines. The former is said to be a great remedy for liver inflammation, peptic ulcer, diarrhea, bronchitis, jaundice and skin diseases, while the latter is often used as an antiseptic. Because of the reported antioxidant activity of wild mint, Indian researchers decided to investigate if it also has antidiabetic properties. In a recent study, which appeared in the Journal of Ayurveda and Integrative Medicine, the researchers looked at the potential of wild mint leaf extract to stop glycation. Glycation refers to the chemical reaction by which a sugar molecule attaches to a protein or lipid. This event is a consequence of hyperglycemia and is associated with the tissue damage often seen in diabetes. The researchers also explored the effect of wild mint extracts on the activity of two carbohydrate-digesting enzymes, as well as their influence on postprandial hyperglycemia. Wild mint extract can prevent blood sugar spikes after meals According to the researchers, interest in the use of alternative medicines to control diabetes, oxidative stress and related disorders has increased in recent years. This is due to the continuous rise in the number of people who develop diabetes around the world. In 2018, this number was estimated to be around 340 million, 70 million of which were from India. Postprandial hyperglycemia, or the increase in blood glucose after eating, is strongly implicated in the development of Type 2 diabetes and diabetic complications. Researchers believe that reducing the postprandial release of glucose in the blood is a promising therapeutic approach to treat or prevent diabetes. To achieve this, two enzymes involved in the breakdown of carbohydrates into sugar are considered as good antidiabetic targets. a-Amylase is a digestive enzyme that converts complex carbs like starch to simple sugars. Similarly, a-glucosidase hastens the digestion of oligosaccharides — three to 10 simple sugars linked together — and disaccharides (e.g., sucrose, maltose, lactose) into glucose molecules. Because of their functions, compounds that can inhibit a-amylase and a-glucosidase activity are used to reduce blood sugar levels in diabetics.  Wild mint is a medicinal herb with a long history of use in traditional medicine. Ancient healers considered it a promising natural remedy for diabetes. To investigate its ability to inhibit postprandial hyperglycemia, the researchers first derived wild mint extract from its leaves using methanol as solvent. They then tested the extract on male rats and performed various in vitro experiments to evaluate the extract’s antidiabetic activity. The researchers reported that the wild mint extract showed a remarkable ability to scavenge free radicals, as well as great potential to inhibit glycation. They noted that it successfully inhibited more than 90 percent of advanced glycation end product (AGE) formation. The wild mint extract also showed high inhibitory activity against a-amylase and ?-glucosidase and significantly inhibited postprandial hyperglycemia in rats with starch-induced diabetes. Based on these findings, the researchers concluded that wild mint has noninsulin-dependent antidiabetic activity and can be used to treat or prevent postprandial hyperglycemia.   Exercise during pregnancy may save kids from health problems as adults University of Virginia, March 15, 2021 Exercise during pregnancy may let mothers significantly reduce their children's chances of developing diabetes and other metabolic diseases later in life, new research suggests. A study in lab mice has found that maternal exercise during pregnancy prevented the transmission of metabolic diseases from an obese parent - either mother or father - to child. If the finding holds true in humans, it will have "huge implications" for helping pregnant women ensure their children live the healthiest lives possible, the researchers report in a new scientific paper. This means that one day soon, a woman's first trip to the doctor after conceiving might include a prescription for an exercise program. "Most of the chronic diseases that we talk about today are known to have a fetal origin. This is to say that the parents' poor health conditions prior to and during pregnancy have negative consequences to the child, potentially through chemical modification of the genes," said researcher Zhen Yan, PhD, a top exercise expert at the University of Virginia School of Medicine. "We were inspired by our previous mouse research implicating that regular aerobic exercise for an obese mother before and during pregnancy can protect the child from early onset of diabetes. In this study, we asked the questions, what if an obese mother exercises only during pregnancy, and what if the father is obese?" Exercise and Pregnancy Scientists have known that exercise during pregnancy helps lead to healthy babies, reducing the risk of pregnancy complications and premature delivery. But Yan, the director of the Center for Skeletal Muscle Research at UVA's Robert M. Berne Cardiovascular Research Center, wanted to see if the benefits continued throughout the children's lives. And his work, both previous and new, suggests it does. To determine that, Yan and his collaborators studied lab mice and their offspring. Some of the adult mice were fed typical mouse chow before and during pregnancy, while other were fed a high-fat, high-calorie diet to simulate obesity. Some receiving the high-fat diet before mating had access to a voluntary running wheel only during pregnancy, where they could run all they liked, while others did not, meaning they remained sedentary.  The results were striking: Both mothers and fathers in the high-fat group could predispose their offspring to metabolic disorders. In particular, male offspring of the sedentary mothers on high-fat diets were much more likely to develop high blood sugar and other metabolic problems in adulthood. To better understand what was happening, the researchers looked at the adult offspring's metabolism and chemical (epigenetic) modification of DNA. They found there were significant differences in metabolic health and how active certain genes were among the different groups of offspring, suggesting that the negative effects of parental obesity, although different between the father and the mother, last throughout the life of the offspring. The good news is that maternal exercise only during pregnancy prevented a host of "epigenetic" changes that affect the workings of the offspring's genes, the researchers found. Maternal exercise, they determined, completely blocked the negative effects of either mother's or father's obesity on the offspring. The results, they say, provide the first evidence that maternal exercise only during pregnancy can prevent the transmission of metabolic diseases from parent to child. "The take-home message is that it is not too late to start to exercise if a mother finds herself pregnant. Regular exercise will not only benefit the pregnancy and labor but also the health of the baby for the long run," Yan said. "This is more exciting evidence that regular exercise is probably the most promising intervention that will help us deter the pandemic of chronic diseases in the aging world, as it can disrupt the vicious cycle of parents-to-child transmission of diseases."   Some veggies each day keeps the stress blues away University of Sydney, March 15, 2021   Published in the British Medical Journal Open, the longitudinal study of more than 60,000 Australians aged 45 years and above measured participants fruit and vegetable consumption, lifestyle factors and psychological distress at two time points . Psychological distress was measured using the Kessler Psychological Distress Scale, a 10-item questionnaire measuring general anxiety and depression. Usual fruit and vegetable consumption was assessed using short validated questions. Key findings   People who ate 3-4 daily serves of vegetables had a 12 per cent lower risk of stress than those who ate 0-1 serves daily. People who ate 5-7 daily serves of fruit and vegetables had a 14 per cent lower risk of stress than those who ate 0-4 serves daily. Women who ate 3-4 daily serves of vegetables had an 18 per cent lower risk of stress than women who ate 0-1 serves daily. Women who ate 2 daily serves of fruit had a 16 per cent lower risk of stress than women who ate 0-1 serves daily. Women who ate 5-7 daily serves of fruit and vegetables had a 23 per cent lower risk of stress than women who ate 0-1 serves daily.   At the start of the study, characteristics associated with higher stress included: being female, younger, having lower education and income, being overweight/obese, a current smoker and being physically inactive.   Fruit consumption alone had no significant association with a lower incidence of stress. There was no significant association between higher levels of fruit and vegetable intake (greater than 7 daily serves) and a lower incidence of stress.   "This study shows that moderate daily fruit and vegetable consumption is associated with lower rates of psychological stress," said Dr Melody Ding of the University of Sydney's School of Public Health. "It also reveals that moderate daily vegetable intake alone is linked to a lower incidence of psychological stress. Moderate fruit intake alone appears to confer no significant benefit on people's psychological stress."   These new findings are consistent with numerous cross sectional and longitudinal studies showing that fruit and vegetables, together and separately, are linked with a lower risk of depression and higher levels of well-being assessed by several measures of mental health.   "We found that fruit and vegetables were more protective for women than men, suggesting that women may benefit more from fruit and vegetables," said first author and University of Sydney PhD student, Binh Nguyen.   The investigators say further studies should investigate the possibility of a 'threshold' between medium and higher levels of fruit and vegetable intake and psychological stress.

W tym odcinku odpowiadam m.in. na pytania czy jedyną słuszną dietą psa jest mięso? czy psy mogą jeść węglowodany? czy diety bezzbożowe to najlepszy wybór dla twojego psa? czy pies może zostać weganinem? Badanie dotyczące amylazy https://www.researchgate.net/publication/263512364_Amylase_activity_is_associated_with_AMY2B_copy_numbers_in_dog_Implications_for_dog_domestication_diet_and_diabete Preferencje dietetyczne psów https://www.sciencedirect.com/science/article/abs/pii/S0168159118305914?via%3Dihub Przyjemnego odsłuchu!

We are currently gathering visuals and information on cresty neck to share with you all. Check back in and follow the Standlee Premium Western Forage facebook page to get first access!Have a topic idea or feedback to share? We want to connect with you! Email podcast@standleeforage.comShare our podcast and learn more about our co-hosts on our Beyond the Barn podcast pageCheck out the Standlee Barn Bulletin BlogFind more nutritional resources from Dr. Stephen Duren and Dr. Tania Cubitt https://standleeforage.com/nutrition/nutritional-resourcesConnect with Standlee on Facebook and Instagram 

The Beyond Clean GoldMind is a free innovative digital dictionary resource for Sterile Processing terms, featuring diverse voices from around the globe who provide definitions to the most common terms in our industry. Releasing 365 days a year, GoldMind is your daily dose of Sterile Processing education and insight to invest in yourself, your future, and the safety of your patient. It is a perfect addition to new technician on-boarding, certification studies, and educational programming in your facility. Subscribe on iTunes: https://podcasts.apple.com/us/podcast/beyond-clean-goldmind/id1534449762 Subscribe on Spotify: https://open.spotify.com/show/2NRaV0f3cWed7ZmxyYFYQB?si=BWjLs0L_QyO2sP1WhjBAGQ For more creative Sterile Processing education & resources, visit us at http://www.beyondclean.net #GoldMind #BeyondClean #DigitalDictionary #WordOfTheDay #Education #SterileProcessing #Voices #Network #Listen #Learn #ChangeTheWorld

Amylase Was ist Amylase? Simple Infos zu Amylase in diesem Kurzvortrag von Sukadev Bretz, dem Gründer von Yoga Vidya. Hier findest du: Seminare mit Sukadev Seminarübersicht Yoga Vidya YouTube Live Kanal Online Seminare Video Seminare Yoga Vidya kostenlose App Yoga Vidya Newsletter Kochrezepte Ayurvedische Ernährung Forum Onlineshop Schon ein kleiner Beitrag kann viel bewegen... Spende an Yoga Vidya e.V.!

Amylase Was ist Amylase? Simple Infos zu Amylase in diesem Kurzvortrag von Sukadev Bretz, dem Gründer von Yoga Vidya. Hier findest du: Seminare mit Sukadev Seminarübersicht Yoga Vidya YouTube Live Kanal Online Seminare Video Seminare Yoga Vidya kostenlose App Yoga Vidya Newsletter Kochrezepte Ayurvedische Ernährung Forum Onlineshop Schon ein kleiner Beitrag kann viel bewegen... Spende an Yoga Vidya e.V.!

This free iTunes segment is just one tiny snippet of the fully-loaded 3-hour monthly Urgent Care RAP show. Earn CME on your commute while getting the latest practice-changing urgent care information: journal article breakdowns, evidence-based topic reviews, critical guideline updates, conversations with experts, and so much more. Sign up for the full show at hippoed.com/UCRAPPOD Matthieu DeClerck, MD, Mike Weinstock, MD, and Cameron Berg, MD sit down to discuss the diagnostic criteria for acute pancreatitis. They discuss workup: the role of imaging to rule out gallstone pancreatitis. They go into risk stratification of acute pancreatitis as well as Initial management: pain control, IV fluids, nutrition. And ultimate disposition – when to go home? When to admit to a higher level of care?   Pearls: Confirmatory CT scanning is rarely needed to confirm pancreatitis Amylase level is neither as sensitive or specific as lipase. Early feeding, has been shown to improve outcomes in patients with pancreatitis. DIAGNOSING PANCREATITIS Must meet 2 of the following 3 criteria: Clinical presentation that is consistent with pancreatitis - epigastric or upper abdominal pain, frequently radiating to the back often with associated with nausea and vomiting, A lipase level that is three times the upper lab limit of normal for a given assay. Do not order an amylase as it not as sensitive or specific for pancreatitis as lipase. The initial lipase level cannot predict outcomes of patients with pancreatitis and there's no utility in trending lipase levels A CT scan demonstrating pancreatic inflammation consistent with pancreatitis. Note: A CT is rarely needed to confirm pancreatitis but it is the gold standard when there is diagnostic uncertainty. Perform a RUQ ultrasound to rule out gallstone pancreatitis as the most common cause of pancreatitis in the United States is biliary. Patients with biliary tract obstruction will need an ERCP or MRCP urgently that many facilities cannot get 24/7. Obtain a triglyceride level as hypertriglyceridemia is the third most common cause of pancreatitis after alcohol and gallstones. MANAGEMENT Not all patients with acute pancreatitis require hospital stay. Consider the following factors before deciding on admission: Patient vital signs Clinical appearance Ability to perform ADLs Presences or absence of markers of end organ stability Patients with pancreatitis who are admitted should receive adequate fluid resuscitation in the form of 2-3L  of IV crystalloid. Feed the patient orally as soon as possible as early enteral nutrition, rather than bowel rest, has been shown to greatly increase recovery. Patients with gallstone pancreatitis and pancreatitis secondary to hypertriglyceridemia require a higher level of care and should be referred appropriately. REFERENCES: Uhl, W. et al. 2003. IAP Guidelines for the surgical management of acute pancreatitis. Pancreatology. Tenner, S. 2013. American College of Gastroenterology Guidelines: Management of Pancreatitis. The American Journal of Gastroenterology.

◦ Diet/gut health -poor eating habits(obviously) -things to stay away from/foods marketed as healthy but really aren't -fat loss helpers -Amylase/bromelian/lipase -supplement biox4 -talk about candida/Catalina fimbriata/egcg =ammo ◦ Fitness ⁃ exercise program/ exercise type ⁃ Intensity can be a problem ◦ Mentality -are you focused enough -trying to move to far to fast -patients consistency is key little by little --- Send in a voice message: https://anchor.fm/ideasinspire/message Support this podcast: https://anchor.fm/ideasinspire/support

Anregungen, Kritik, Wünsche? Wie immer gerne unter ehle1198@uni-landau.de oder nach 9448@uni-landau.de

Amylase- Definitionen und Gedankengänge Gerne kannst du deine Gedanken dazu in die Kommentare schreiben. Yogatherapie Weiterbildung findest du hier. Psychologische Yoga Therapie Weiterbildungen findest du hier. Dieser Audio-Lexikon-Beitrag zum Ameisensäure ist im Rahmen des Bewusst Leben Multimedia Lexikon von Yoga Vidya, Teil des umfassenden Lexikons zu Yoga, Meditation, Ayurveda, Naturheilkunde, Spiritualität, Gesundheit, Philosophie, Religion und Psychologie. Dieser Vortrag ist ursprünglich konzipiert worden als Diktatgrundlage für den Wiki-Artikel. Wir haben uns aber entschlossen, diesen Vortrag allen auch als Audio zur Verfügung zu stellen. Diese Naturheilkunde Vorträge findest du als Podcast hier und abonnierbar hier. Hinweis: Die Infos und Tipps zu Gesundheit und Heilung sind nicht gedacht zur Selbstdiagnose und Selbsttherapie. Sie sind vielmehr allgemeine Informationen. Wenn du selbst erkrankt bist, solltest du einen Arzt oder Heilpraktiker aufsuchen. Eventuell können dir die Anregungen in diesem Beitrag beim Gespräch mit Arzt oder Heilpraktiker hilfreich sein.

Amylase- Definitionen und Gedankengänge Gerne kannst du deine Gedanken dazu in die Kommentare schreiben. Yogatherapie Weiterbildung findest du hier. Psychologische Yoga Therapie Weiterbildungen findest du hier. Dieser Audio-Lexikon-Beitrag zum Ameisensäure ist im Rahmen des Bewusst Leben Multimedia Lexikon von Yoga Vidya, Teil des umfassenden Lexikons zu Yoga, Meditation, Ayurveda, Naturheilkunde, Spiritualität, Gesundheit, Philosophie, Religion und Psychologie. Dieser Vortrag ist ursprünglich konzipiert worden als Diktatgrundlage für den Wiki-Artikel. Wir haben uns aber entschlossen, diesen Vortrag allen auch als Audio zur Verfügung zu stellen. Diese Naturheilkunde Vorträge findest du als Podcast hier und abonnierbar hier. Hinweis: Die Infos und Tipps zu Gesundheit und Heilung sind nicht gedacht zur Selbstdiagnose und Selbsttherapie. Sie sind vielmehr allgemeine Informationen. Wenn du selbst erkrankt bist, solltest du einen Arzt oder Heilpraktiker aufsuchen. Eventuell können dir die Anregungen in diesem Beitrag beim Gespräch mit Arzt oder Heilpraktiker hilfreich sein.

Brian Clegg on the enzymes make life a little sweeter by breaking down starch into sugars, helping to make bread and beer

Broad Spectrum Digestive Enzymes Children on the autism spectrum have difficulty digesting their food properly. This means they do not absorb the nutrients from the foods they eat. This starves their brain of what it needs to function properly. Broad spectrum enzymes assist in the digestion of many foods including protein, carbohydrates, fats, and fiber. Enzymes are naturally produced by the body unless the GI tract is not working properly. If so, digestion and absorption of nutrients and many other factors are effected. Enzymes can be very helpful when taken just before or with meals to help break down food particles, proteins, carbohydrates, and fats. The enzyme known as DPPIV helps break down the large proteins in wheat known as gluten, and casein in dairy. Enzymes for Therapeutic use When enzymes are taken away from food they can be helpful as little garbage collectors in the sense of cleaning up the toxic debris from various viral and bacterial issues. Benefits Beyond Digestion Enzymes can be extremely helpful with the sensitive digestion needs of those with autism, ADHD, allergies, and more. By improving digestion there can be a reduction in inflammation in the GI tract, therefore, better overall health. Keeping the gut healthy is crucial. The gut has receptors that make neurotransmitters for the brain such as serotonin which effects mood, appetite, and sleep, and GABA which acts to calm nerve function. Enzymes also act as little garbage collectors cleaning up toxic debris .   From using enzymes parents report better concentration, increased language abilities, improved digestion, and behavior.   Help with positive gut bacteria and phenols There are beneficial microorganisms in the gut that are built from fiber foods such as vegetables. If the GI tract is compromised and weak it can have trouble digesting fiber. Additionally, Phenols are a compound found in many healthy foods including vegetables and dark colored fruit. These are healthy foods but our kids may be sensitive to them. One enzyme formula that can be helpful with both fiber digestion and phenols is No-Phenol from Houston-Enzymes. They come in capsules and chewable form.    Some Common Enzymes are: • Dipeptidyl peptidase IV (DPP-IV) breaks down casomorphin (from casein) and gluteomorphins (from gluten) • Proteases break down proteins • Lactase breaks down lactose (found in dairy) • Amylase for starch (carbohydrate) digestion • Alpha-galactosidase breaks down beans and other fiber-rich foods • Xylanase helps digest fruits and vegetables (phenolic foods) • Beta-glucanase for fiber-rich vegetables and grains • Lipase breaks down lipids or fats • Bromelain and papain are enzymes derived from pineapple. They break down proteins. Note: Some people exhibit sensitivities to fruit or citrus, so watch for signs of this from your child. Cellulase may interfere with some time-released, cellulose-based medications. Ask your doctor or check your labels for hydroxypropyl cellulose, or hypromellose. Some products come as “cellulose-free”. Quality Products Broad spectrum digestive enzymes are taken just prior to eating a meal for their assistance in digestion. This helps the body absorb nutrients for better health and well being. There are several great products available such as Trienza by Houston-Enzymes.  This formula has the added benefit of DPP-IV, a specific enzyme that breaks down the larger proteins in dairy and wheat products that can injure the gut lining and create toxins in the blood which make their way to the brain. This often triggers an allergic response to these foods. Trienza also comes in a chewable form. The size of the meal often determines the dosage. Start slowly with half the recommended dosage and work your way up to the full amount over a 12-14 day period. The beauty of broad spectrum enzymes is that they assist with so many different types of foods. We do not always know exactly what disturbs our digestion. This way we cover a multitude of possibilities with one product. Radio Show interview Please listen to my radio show interview with Dr. Devon Houston of Houston-Enzymes. It is show #44. You can find it here. About Dr. Houston Devin Houston Ph.D. Incorporator and CEO of Houston Nutraceuticals Dr. Houston obtained a B.A. degree in Biology from Hendrix College in 1979. He then was awarded a B.S. degree in Medical Science in 1980 and a Ph.D. in Biochemistry from the University of South Alabama College of Medicine in 1987. Dr. Houston’s graduate work focused on how the aging process affected certain enzyme systems. Click Here for more details.

I read from amu to amylase. dictionarypod@gmail.com https://www.facebook.com/thedictionarypod/ https://twitter.com/dictionarypod https://www.patreon.com/spejampar 917-727-5757

How is food broken down before it even touches your stomach acid? Today I am going to be talking about this process—something I like to call predigestion—and explaining the importance of chewing your food and more. You can find show notes and more information by clicking here: http://thedigestiondoctor.com/99 

Bill Nye nerds out on PB&J, explains why he now supports GMOs, and answers our burning food science questions: Does mashing bananas actually make them sweeter? How long before there’s affordable lab-grown meat? Does adding salt to water make it boil faster? On his new podcast, Science Rules!, Bill and science writer Corey S. Powell answer questions on just about anything in the universe. This episode is from The Sporkful's archives. Normally, this episode and hundreds like it are only available with Stitcher Premium. But in these strange times, we're releasing it for free — both to help our listeners through self-isolation, and to say thanks for continuing to support our show. If you'd like to have access to our entire archive, you can sign up for Stitcher Premium at www.stitcherpremium.com/SPORKFUL, and use the promo code SPORKFUL for a special discount.  

In this episode of the WSU Wheat Beat podcast, Drew Lyon interviews Camille Steber all about alpha-amylase and low falling numbers in wheat. TRANSCRIPTION: http://smallgrains.wsu.edu/wsu-wheat-beat-episode-43/ RESOURCES MENTIONED: Camille Steber's lab http://steberlab.org/ Grain Quality Resources http://smallgrains.wsu.edu/grain-quality-resources/ CONTACT INFORMATION: Contact Camille Steber by email at csteber@wsu.edu or by phone at 509-335-2887.

Did you know that Amylase is the enzyme responsible for converting starchy foods into sugar and is also used in making alcohol? On this episode, Ashdin talks about the importance of chewing your food until it turns liquid and the habit of eating meals using a teaspoon. You can follow Ashdin Doctor on Instagram @ashdindoc You can listen to this show and other awesome shows on the IVM Podcast App on Android: https://goo.gl/tGYdU1 or iOS: https://goo.gl/sZSTU5 You can check out our website at http://www.ivmpodcasts.com/

ITS TOM'S BIRTHDAY! .... but in other news, there was some questionable advice given out this week on amylase, orange juice, coffee and caffeine by a fun duo of a popular strongman and the truly awful DNA testing company.

I've been getting a lot of questions lately about the mysterious molecule I consume before I eat bread and pasta - a compound that allows me to digest gluten without any of the "bathroom decommissioning" that so notoriously occurs after a hefty bout of gluten consumption. After all, I don't want to not eat bread or pasta for the rest of my life. I find them enjoyable. But due to glyphosate exposure from pesticides and herbicides, stress, a leaky gut and other modern assailants that make gluten a bigger issue than it ever has been in human history, I use a bit of better living through science to make gluten digestible. In today's podcast, I interview the inventors of Gluten Guardian - Matt Gallant and Wade Lightheart - the guys who first appeared in the podcast "" and later in my article "". Matt Gallant is an entrepreneur, a poker champion, an ex-rock guitarist, a serial entrepreneur (who's built 13 companies in the last 20 years) strength and conditioning coach with a degree in kinesiology, the CEO and co-founder of a company called BiOptimizers. Wade T. Lightheart, host of the AWESOME Health Podcast, 3-time All Natural National Bodybuilding Champion, advisor to the American Anti-Cancer Institute and Cofounder of BiOptimizers. He is also the author of several books including the best-selling books, “Staying Alive in a Toxic World” and “The Wealthy Backpacker.” MARGE LINK TO WADE'S BOOKS During our discussion, you'll discover: -Why Matt eats between 6-10,000 calories every Sunday...7.36 For the calorie spike. One meal per day for 6 days. A combo of healthy and regular food. Matt feels great afterwards. He takes the day off from training. -Why we should be cognizant of our gluten intake, even if we don't have celiac disease...10:30  New England Journal of Medicine listed 55 diseases that can be caused by eating gluten. Many times we're not aware of these diseases; can be immune, neurological and psychiatric. Differences between wheat germ in the gluten and gluten itself. Different type of protein. Both are resistant to digestion. Can make the gut more permeable. (Leaky gut) Amylase/trypsin inhibitors come packaged with gluten - specifically wheat. What about other factors to leaky gut such as stress and glyphosate. 4x increase in celiac disease; traced to glyphosate interrupting the digestive process. Will continue to increase due to the exposure to glyphosate.  -The use of enzymes in the preparation of food to increase its palatability...18:10 In a perfect world, you'd be eating pre-digested food primarily. You use enzymes to assist with breaking food down. -Do Matt and Wade recommend any panels for evaluating gluten sensitivity or gluten cross reactivity?...20:30 Anti-tissue trans glutaminase or endomysial antibody. Recommend Cyrex. Helps you know if other foods such as coffee or quinoa are exacerbating your level of gluten intolerance. Also testing gliad and peptide antibodies. How does gluten negatively affect the brain?...24:00 Inflames the brain by causing an auto-immune response. Antibodies intended to protect your body actually attack your body. During the digestive process, gluten can be broken down into proteins similar to psychedelic drugs. Has an addictive quality. Overloads the brain with glutamate. Irritates and damages brain cells. Negative impact on your social life. -What Wade REALLY thinks about Monsanto...29:50 They were written into protection against lawsuits by federal law during the previous administration. Demonstrable evidence of their products causing damage to the body. Has been bought out by Bayer. Food has essentially been mutated, much to our detriment. Destroy livelihoods of small farmers. -The product Matt uses to pre-digest gluten before you even eat it...37:00 Dipeptidyl peptidase 4, also DPP-4. Dissolves bread placed in water in 15 minutes (watch the video below) You take it while you eat. Does DPP-4 actually mitigate symptoms of gluten intolerance? Depends on the dosage. Can be taken as late as the day after eating. Citrusy foods have been found to inhibit DPP-4 Breaks down various hormones in the body such as insulin. -Does DPP-4 have any effect on foods not containing gluten?...45:00 Milk proteins, but not milk sugars like lactose. Good idea to add DPP-4 if you have a plant-based diet. Just mix and match until you find the right combination for you, and for the right meals. Safe for children to ingest. -More on Matt and Wade's diet and workout regimen...49:50 -How do HCL and hydrochloric acid work with Gluten Guardian?...54:55 Plays a supportive role Stomach acid decreases after the age of 35 Simulates the effects of apple cider vinegar P3-OM  Optimal time to take is before bed or first thing in the morning, rather than meal time. -Matt plays "myth busters" with colonizing properties of probiotics...58:41 -Special offer from Matt and Wade...1:04:15 Get 10% off your order of Gluten Guardian when you use code "greenfield" at 365 day unconditional money-back guarantee Brand new offer: "we'll fix your digestion guarantee" Resource from this episode: -Masszymes -Cyrex blood panel for gluten allergy -Book: Grain Brain Episode Sponsors: - utilizes sound waves to optimize sexual performance and reverse the effects of ED. Purchase 6 treatments, and get the 7th treatment for FREE. - Discover Omax3, the 93.9% pure omega-3 supplement developed by Yale-affiliated scientists. Use my link and you can try an entire box for FREE, plus get 60% off your first month's supply. - Organic brands you love, for less. Get your favorite Organic & Non-GMO brands delivered to your door! Get 25% off your first order when you use my link. - Make the cold your secret weapon with next-level cold gear. Enter code "ben" at checkout and receive 15% off your order! Do you have questions, thoughts or feedback for Matt, Wade or me? Leave your comments at http://bengreenfieldfitness.com/glutenpodcast and one of us will reply!

Standardization efforts for amylase have been limited by a lack of commutability in the current certified reference material.  New candidate reference materials have been developed to potentially overcome this limitation, facilitating their use for calibration and trueness control of routine measurement systems.  An original article appearing in the August of 2018 issue of Clinical Chemistry describes the commutability assessments of these new candidate reference materials for pancreatic alpha amylase.  The authors investigated if a reference material with an artificial matrix could be commutable for routine methods and compared to different statistical approaches to assess the commutability of the candidate reference materials.

Dave, Nastassia, and everybody’s favorite punching bag dad Peter Kim ruminate over the hectic opening (at last) of Existing Conditions and its POS POS system, carbonated salsa, Montreal-style bagels, amylase, gelato, that time Peter walked in on Dave, and more! Cooking Issues is powered by Simplecast

Hallo und herzlichen Willkommen zu einer neuen Podcastepisode! Ich hatte in der vergangenen Zeit ein paar kleine Probleme mit der Technik. Heute möchte ich dir gern eine neue Folge präsentieren. Zu Gast habe ich Mark Weiland, der mit mir gemeinsam das heutige Thema „durchkaut“. Smoothies sind in aller Munde und der Hype wächst! Wir klären auf, was wir von Smoothies halten und warum solche gemixten Getränke auch kritisch betrachtet werden sollten. Viel Spaß beim Anhören! Shownotes: Vorstellung Mark von Weiland-wissen.de Wo begann der Hype mit Grünen Smoothies? Warum ist richtiges Kauen so wichtig? Statt Smoothies trinken, Smoothie Bowls zubereiten! Langsames Essen ist unglaublich wichtig für die Verdauung und die Aufnahme von Nährstoffen. Über die positiven Aspekte geht es im zweiten Teil!   Dinge, über die wir gesprochen haben Green For Life – Victoria Boutenko  handverzierte Kokosnuss-Schalen für Deine Smoothie-Bowls     ▼▼▼Warum ist richtiges Kauen so wichtig? Hier findest die komplette Liste:▼▼▼ Zerkleinerung durch reaktionsneutrale Zähne Zerkleinerung im geschlossenen Mundraum (weitgehend geschützt vor dem Luftsauerstoff), Vitalstoffe werden bereits aufgenommen (Mundschleimhaut), vor der Magensäure bewahrt und nicht zerstört durch Oxidation. Der Mundspeichel hat antibakterielle und antivirale Eigenschaften. Intensives Kauen verstärkt diese Wirkung enorm. Enzyme – die Verdauung beginnt im Mund: alpha-Amylase 1 = Ptyalin: Stärke in Oligosaccharide pH 5,7 optimal, saurer bedeutet Abnahme der Enzymaktivität. Im Dünndarm werden die Oligosaccharide dann durch eine weitere Amylase in Disaccharide wie Maltose aufgespalten und letztlich durch Maltase (in der Gallenflüssigkeit) in Glucose (Monosaccharid) zerlegt. Die Pankreas-Amylase setzt die vorbereitete und noch nicht vollendete Arbeit (Aufspaltung von Stärke) dann fort. Anwärmen auf Körpertemperatur Rezeptoren nehmen Geruch und Geschmack auf, stimulieren den Vagusnerv und regen die Magensaft-Produktion an. Intensives Kauen verbessert also die Verdauungsaktivitäten im Magen-Darm-Trakt. Zahnreinigung Zahnfleischmassage bewirkt bessere Durchblutung Gut kauen heißt Kaumuskeltraining. Richtiges Kauen bewirkt daher auch eine bessere Durchblutung der Kaumuskeln. Gutes Kauen bedeutet Anregung der 3 großen Speicheldrüsen. Der Zahnapparat wird durch richtiges Kauen erhalten. Der piezoelektrische Effekt wirkt dem Unterkieferschwund entgegen, beim Kauen entstehen elektrische Ströme, die Heilung, Aufbau und Erhalt des Knochens bewirken. Dieser positive Effekt wird durch Kraftaufwendung mit Widerstand (durch die Kaumasse) erhöht. Deshalb gibt es Unterkieferschwund nach Totalausfall der Zähne durch Nichtbeanspruchung Thema Entsaften: Faser- und Ballaststoffe regen die Darmperistaltik an und dienen auch der natürlichen Entgiftung (z.B. Abtransport der Gallensäure) und sie bieten für wichtige Verdauungsbakterien die Grundlage, welche wiederum Vitamin K und B12 bilden. Allerdings entzieht man den Lebensmitteln beim Entsaften diese Faser- und Ballaststoffe. Das geschieht beim Mixen Zerkleinerung Verwirbelung mit dem Metall + Interkation mit Obstsäure führt zu Oxidation durch Sauerstoff, Substanzverlust von Vitalstoffen, z. B. Vitamin C Die magnetische Struktur/Information der Lebensmittel, die ursprünglich durch das Einwirken des Erdmagnetfelds entstanden ist wird durch das Mixen zerstört Wird Stärke nicht richtig verdaut, kann sich Schleim in der Lunge bilden, Infekte im Mittelohr und der oberen Atemwege, der „Frosch im Hals“ kann auch daher kommen. Die Kaumasse zur Anregung der Speicheldrüse fehlt, weshalb nur wenig Amylase-Produktion stattfindet.   VERBINDE DICH MIT MARK ➥ Facebook: https://www.facebook.com/weiland.wissen/ ➥ Instagram: https://www.instagram.com/weilandwissen/ ➥ Twitter: https://twitter.com/WEILANDWISSEN ➥ Google Plus: https://plus.google.com/+WEILANDWISSEN ➥ YouTube https://www.youtube.com/c/WEILANDWISSEN  

Gedanken und Überlegungen zu Amylase. Simple und komplexe Gedankengänge über Amylase in diesem Kurzvortrag. Eine Ausgabe des Naturheilkunde Podcasts von und mit Sukadev Bretz, Yogalehrer bei Yoga Vidya. Anmerkung: Gesundheitliche Informationen in diesem Podcast sind nicht gedacht für Selbstdiagnose und Selbstbehandlung, sondern Gedankenanstöße aus dem Gebiet der Naturheilkunde. Bei eigener Erkrankung brauchst du Arzt oder … „Amylase“ weiterlesen

This week on Cooking Issues, Dave and Nastassia are joined in the studio by Don Lee, Evil Cocktail Overlord of the Universe. Tune in to hear the about the latest Spinzall news, Dave's aversion to exposed wires, pectinex, amylase, agar, carbonated cocktails, artificial sweeteners, and more! Cooking Issues is powered by Simplecast

Digestive enzymes might be the most overlooked, underappreciated part of a good nutrition plan. Even the healthiest diet does little if you don't have good digestive health.  Unfortunately, most people don't think about using them unless they have issues with their gut health. As you'll see, they're essential for more than breaking down the food you eat. They can play a role in weight loss, muscle growth, and aging well. Not surprisingly, they're part of my Foundational Five. About 20% of the US population is known to have a digestive issue. That's about 60-70 million people. The percentage continues to grow in the US and across the world.  Symptoms can be as subtle as gas and bloating to more extreme symptoms like constant diarrhea or intermittent pain. Exercise, increased core body temperature, injury, stress, and certain diseases can compromise enzyme production. Processed foods may deplete enzyme activity and availability.  Digestive enzyme insufficiency may contribute to: Irritable Bowel Syndrome (IBS)hyperthyroidismCeliac diseaseCrohn's disease Excessive exercise and diets high in processed foods contribute to a lack of enzymes. What are Digestive Enzymes? Enzymes speed up chemical reactions in the body. You use more than 5000 different enzymes every day. Most of those enzymes are metabolic enzymes, responsible for everything from your thoughts to the thickness of your blood. A relatively small group of your 5000 enzymes convert the food you eat to nutrients that fuel and build your body. Without digestive enzymes, you wouldn't break down protein, fat, and carbohydrates, and your foods would pass through you undigested. Along the way, the food would destroy your intestines' lining, cause immune reactions, and cause inflammation. Nutritionally, you'd starve, no matter how much food you ate. Digestive enzymes fall into three different categories, based on the macronutrient they act on: Proteases and peptidases: Convert protein to peptides and amino acids. They also act on other parts of the body to support normal immune function, inflammation levels, tissue repair, and blood viscosity.Common proteases and peptidases: Bromelain, Pancreatin, Papain, Peptidase, Protease, TrypsinCarbohydrases: Convert carbohydrates to glucose and fructose.Common carbohydrases: Alpha-galactosidase, Amylase, Cellulase, Diastase, Glucoamylase, Invertase, Lactase, PhytaseLipases: Convert fat to fatty acids.Common lipases: Lingual Lipase, Gastric Lipase, Pancrealipase Proteases and Peptidases (Proteolytic Enzymes) Proteases (also known as proteolytic enzymes) act on protein in the digestive system. However, they also affect many other areas of the body. The average healthy adult breaks down 250-300 grams of protein throughout the body every day. Your body does this to replace damaged or aged tissues with new ones. Proteolytic enzymes play an essential role in this process. They also help maintain healthy inflammation levels, modulate pain, and support normal immune function. Because the body can produce a limited number of proteolytic enzymes, demand can exceed supply. Following an injury or extreme physical stress, proteolytic enzymes can be directed to the tissue repair, leaving the digestive system without enough to complete digestion. This could be why athletes often deal with digestive issues. If they don't get extra proteolytic enzymes through food or supplements, their available enzymes take part in tissue repair, leaving them short on what they need for proper digestion. On the other hand, in some people, enzymes are directed to digestion, leaving the rest of their body short. In this case, inflammation could get out of hand, or tissues and joints could get irritated. When supplemented in the diet, proteolytic enzymes have been shown to reduce stiffness and exercise-related soreness.* European practitioners regularly recommend proteolytic enzymes to support overall healt...

This week on Humerus Hacks we talk about the pancreas, getting smashed and the fabulous Tituss Burgess. You'll laugh, you'll cry, you'll be confused and then you'll see the light! 

The post Amylase appeared first on NURSING.com.

Keaton Jones, Academic Clinical Fellow at the University of Oxford, talks to Ash Bhalla, Research Fellow in Surgery at the University of Nottingham, about pancreatitis. This audio podcast is mapped to learning outcomes for medical undergraduates and core surgical trainees (junior residents), and covers presentation, diagnosis, investigations, scoring systems, prognosis and complications of pancreatitis - so all you really need to know about this common acute surgical condition!

Chemistry and lightning quick reactions are under discussion this week as Emma Schofield explains what a catalyst is, how catalytic converters work and how catalysts can help to clean up the atmosphere, and Fraser Armstrong discusses fuel cells, using hydrogen as a fuel and how enzymes naturally found in bacteria are making hydrogen a more realistic energy source for the future. In Kitchen Science, both guests are used as guinea pigs as Dave Ansell demonstrates the wonder of enzymes with nothing but a slice of bread... Like this podcast? Please help us by supporting the Naked Scientists

Chemistry and lightning quick reactions are under discussion this week as Emma Schofield explains what a catalyst is, how catalytic converters work and how catalysts can help to clean up the atmosphere, and Fraser Armstrong discusses fuel cells, using hydrogen as a fuel and how enzymes naturally found in bacteria are making hydrogen a more realistic energy source for the future. In Kitchen Science, both guests are used as guinea pigs as Dave Ansell demonstrates the wonder of enzymes with nothing but a slice of bread... Like this podcast? Please help us by supporting the Naked Scientists

The molecular requirements for amylase release and the intracellular effects of botulinum A toxin and tetanus toxin on amylase release were investigated using rat pancreatic acinar cells permeabilized with streptolysin O. Micromolar concentrations of free Ca2+ evoked amylase release from these cells. Maximal release was observed in the presence of 30 microM free Ca2+. Ca(2+)-stimulated, but not basal, amylase release was enhanced by guanosine 5'-[gamma-thio]triphosphate (GTP[S]) (3-4 fold) or cyclic AMP (1.5-2 fold). Neither the two-chain forms of botulinum A toxin and tetanus toxin, under reducing conditions, nor the light chains of tetanus toxin, inhibited amylase release triggered by Ca2+, or combinations of Ca2+ + GTP[S] or Ca2+ + cAMP. The lack of inhibition was not due to inactivation of botulinum A toxin or tetanus toxin by pancreatic acinar cell proteolytic enzymes, as toxins previously incubated with permeabilized pancreatic acinar cells inhibited Ca(2+)-stimulated [3H]noradrenaline release from streptolysin O-permeabilized adrenal chromaffin cells. These data imply that clostridial neurotoxins inhibit a Ca(2+)-dependent mechanism which promotes exocytosis in neural and endocrine cells, but not in exocrine cells.