Podcasts about Differential

Plenty of Wildcards are being activated and almost all are doing so to bring in Man City forward Erling Haaland

After playing an hour for Liverpool midweek, FPL managers are already starting to bring Alexander Isak into their teams. But have they gone too soon?

All In Football FPL Show's Differential Kings GW5The Differential King reviews his Kings selections for GW4 to see who won fixture or form.The King talks through the Top 5 in form differentials (5% or Under) for GW5 and he picks his Kings that have a good fixture and is worth looking at.Do you agree? Has he missed any?Let him know in the comments and don't forget to like, subscribe and give us a 5 Star's Hosted on Acast. See acast.com/privacy for more information.

All In Football FPL Show - Episode 151 - Who's In Good NICK?This episode the All In Football FPL Show team looked at teams with good fixtures and FPL players in good form.The All In Football FPL Team discussed the below football topics:What's going wrong with Villa? Hold, Sell or Buy?Will Forest get a new manager bounce? Worth investing?Have Tottenham gone from Spursy to Dependable?Have Wolves bitten off more than they can chew?Man City too good or was Man U so poor?Which Players are in Form?Can Potter produce some magic in his next 3 Games?Differential 5-A-SideFixture Review and Captain Selections Hosted on Acast. See acast.com/privacy for more information.

Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is the fastest-growing etiology of hepatocellular carcinoma (HCC). This work identifies novel gene and lipid associations in human MASLD-driven HCC that may be exploited for therapeutic benefit. Methods: Human HCC tumor (n=8) and adjacent non-tumor samples (n=8) were obtained from the Biospecimen Procurement and Translational Pathology Shared Resource Facility at the University of Kentucky Markey Cancer Center. All patients met cardiometabolic MASLD criteria and were negative for viral hepatitis. Hematoxylin and eosin (H&E) staining was used for pathological determination of tumor and adjacent nontumor tissue. Lipids were extracted using a methyl-tert-butyl ether extraction method and subjected to lipidomics by the West Coast Metabolomics Center. RNA was isolated and used for bulk sequencing. Data were analyzed using paired nonparametric analyses via a Wilcoxon or Mann-Whitney test, as appropriate. Results: Histological analysis by H&E showed significant lipid vacuole accumulation in HCC tumors relative to nontumor tissue. Lipidomic analysis revealed significant increases in long-chain nonesterified monounsaturated fatty acids (MUFAs; C16:1, C18:1, C20:1) and MUFA-enriched phospholipids (PC30:1, PC32:1, PE32:1, and PC36:1) in tumors relative to nontumor tissue. No significant differences were observed in nonesterified polyunsaturated fatty acids (PUFAs; C18:2, C20:4, and C22:6), PUFA-enriched phospholipids (C36:4, C38:4, C38:6, C40:6), or in fatty acid esters of hydroxy fatty acids (FAHFAs; C38:2, C38:4, C38:6). However, both MUFA- (C14:1, C18:1) and PUFA-enriched acylcarnitines (C18:2, C18:3) were collectively reduced in human tumors. Differential analysis of RNA sequencing revealed fatty acid oxidation genes (CPT1A, CPT2, ACADL, ACADM, ACADS, HADHA) were significantly reduced in tumor versus nontumor tissue. Further, genes involved in de novo lipogenesis were largely dysregulated (e.g. no differences in SREBF1 or FASN; increases in ACLY, ACACA, and SCD1; decreases in ACSL1) in tumor versus nontumor tissue. Conclusions: These results suggest human HCC tumors exhibit a reduced capacity to undergo mitochondrial β-oxidation resulting in accumulation of free and esterified MUFAs with concomitant reductions in MUFA-carnitines. Current studies are underway to determine the mechanisms by which impairment of hepatic MUFA catabolism via FAO promotes the development of HCC in mice.

In this episode of Through a Therapist's Eyes, we unpack the often-misunderstood world of Obsessive-Compulsive Personality Disorder (OCPD) and explore how it differs from both everyday perfectionism and OCD. From the importance of accurate differential diagnosis to the ego-syntonic traits that make OCPD so challenging to recognize, we highlight how this disorder impacts relationships, marriages, and workplace dynamics. Using a case illustration and insights from marriage research, we discuss how rigidity and control can create friction while offering practical strategies for individuals, partners, and clinicians to foster awareness, flexibility, and healthier connections. Tune in to see OCPD Through a Therapist's Eyes.  

Die Eltern sind doof und Freundschaften einfach das Wichtigste. In dieser Folge erklärt Bent Freiwald, warum das Gehirn von Jugendlichen gar nicht anders kann, als Anerkennung von Gleichaltrigen zu suchen.Hier geht's zur Folge: Pubertät – Was ist da los im Gehirn?Hier geht's zu Bents Buch: Wer denkt, ist klar im Vorteil und hier kannst du dir das Hörbuch dazu vorbestellen. Hier geht's zum gleichnamigen Newsletter: Das Leben des BrainSchreibt uns Feedback an: brain@acbstories.comLinks zu Quellen und verwendeten Studien:1. Neural correlates of prosocial peer influence on public goods game donations during adolescence2. Probing the neural correlates of anticipated peer evaluation in adolescence3. Differential effects of parent and peer presence on neural correlates of risk taking in adolescence Hosted on Acast. See acast.com/privacy for more information.

All In Football FPL Show's Differential King recaps his picks for GW3.The king picks his in form kings and fixture kings explains why he's picked these.Do you agree? Has he missed any?Comment with your choices or who you agree on. Hosted on Acast. See acast.com/privacy for more information.

All In Football FPL Show - Episode 150 - Making Decisions CRYSTAL ClearThis episode the All In Football FPL Show team concentrated on the next 4 fixtures to get us through to the next international break.We discussed the below football topics:League Review and Manager of the Month/WeekFixture CongestionWhat to do with Liverpool Attackers?Who's the best Newcastle FPL Asset?Fixture over Form for Aston Villa FPL Assets?How Many Tottenham FPL Assets to Have and Who?Time to Invest in Bournemouth?Injury Crisis for Crystal Palace, Who to Pick or Stay Away?Differential 5-A-SideFixture Review and Captain Selections Hosted on Acast. See acast.com/privacy for more information.

Ein Vortrag der Primaten- und Kognitionsforscherin Julia FischerModeration: Katrin Ohlendorf**********Je älter wir werden, desto klarer wird, dass Alterung uns betrifft. Was können wir in Bezug auf das Altern von unseren Artverwandten, den Affen, lernen? Ein Vortrag der Primaten- und Kognitionsforscherin Julia Fischer.Julia Fischer leitet die Abteilung Kognitive Ethologie am Deutschen Primatenzentrum und ist Professorin für Primatenkognition an der Universität Göttingen. Ihr Forschungsinteresse gilt dem Sozialverhalten, der Kommunikation und der Kognition nichtmenschlicher Primaten.Im Jahr 2025 hat sie die Johannes Gutenberg-Stiftungsprofessur an der Universität Mainz übernommen. In diesem Rahmen hielt sie eine Studium-Generale-Vorlesungsreihe mit dem Titel "Der Mensch im Spiegel des Affen – Zur Evolution von Sozialverhalten, Kommunikation und Intelligenz bei Primaten". Ihr Vortrag "Kommunikation – Wie Affen kommunizieren und was uns das über den Sprachursprung verrät" wurde am 20. Mai 2025 aufgezeichnet.**********Schlagworte: +++ Wissenschaft +++ Primaten +++ Kognitionsforschung +++ Evolution +++ Affe +++ Mensch +++ Schimpansen +++ Meerkatzen +++ Paviane +++ Tiere +++ Afrika +++ Forschung +++ Altern +++ Alter +++ Demographischer Wandel +++ Sozialleben +++ Alleinsein +++ Einsamkeit +++ Lebensplanung +++ Bucketlist +++ Alterung +++**********Quellen aus der Folge:Carstensen, L. L., Isaacowitz, D. M., & Charles, S. T. (1999). Taking time seriously: A theory of socioemotional selectivity. American Psychologist, 54(3), 165–181.Almeling, L., Hammerschmidt, K., Sennhenn-Reulen, H., Freund, A. M., Fischer, J. (2016). Motivational Shifts in Aging Monkeys and the Origins of Social Selectivity. Current Biology, 26.13 (2016), pp. 1744–49.Rathke E.-M., Fischer J. Social aging in male and female Barbary macaques. Am J Primatol. 2021 Nov; 83(11).Rathke E.-M., Fischer J. (2020): Differential ageing trajectories in motivation, inhibitory control and cognitive flexibility in Barbary macaques (Macaca sylvanus). Philos Trans R Soc Lond B Biol Sci. 2020 Nov 9. https://doi.org/10.1098/rstb.2019.0617 Bosshard, T., Roger, M. & Julia, F. (2024). Ecological risk-taking across age in Barbary macaques. (Preprint)**********Mehr zum Thema bei Deutschlandfunk Nova:Primatenforschung: Vorsicht, Leopard! Wie Affen sich verständigenLebenserwartung: Die Biologie des AlternsPopulationsgenetik: Menschheitsgeschichte in den Genen ablesen**********Den Artikel zum Stück findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .

We break down pneumothorax: risks, diagnosis, and management pearls. Hosts: Christopher Pham, MD Brian Gilberti, MD https://media.blubrry.com/coreem/content.blubrry.com/coreem/Pneumothorax.mp3 Download Leave a Comment Tags: Chest Trauma, Pulmonary, Trauma Show Notes Risk Factors for Pneumothorax Secondary pneumothorax Trauma: rib fractures, blunt chest trauma (as in the case). Iatrogenic: central line placement, thoracentesis, pleural procedures. Primary spontaneous pneumothorax Young, tall, thin males (10–30 years). Connective tissue disorders: Marfan, Ehlers-Danlos. Underlying lung disease: COPD with bullae, interstitial lung disease, CF, TB, malignancy. Technically, anyone is at risk. Symptoms & Differential Diagnosis Typical PTX presentation: Dyspnea, chest pain, pleuritic discomfort. Exam clues: unilateral decreased breath sounds, focal tenderness/crepitus. Red flags (suggest tension PTX): JVD Tracheal deviation Hypotension, shock physiology Severe tachycardia, hypoxia Differential diagnoses: Pulmonary: asthma, COPD, pneumonia, pulmonary edema (SCAPE), ILD, infections. Cardiac: ACS, CHF, pericarditis. PE and other acute causes of dyspnea. Diagnostics Bloodwork: limited role, except type & screen if intervention likely. EKG: reasonable given chest pain/shortness of breath.

With the international break on the horizon and some underwhelming form, Kelly Somers and the FPL Pod team debate whether we should be removing Cole Palmer from our teams

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Mike Schopp talks to Bills fans about the Bills turnover differential from last year and if that is obtainable again

Ekitiké One Gameweek into the new season and FPL managers are already trying to rip up their teams and start again

In this episode of the Epigenetics Podcast, we talked with Luca Magnani from Institute of Cancer Research and UNIMI in Milan about his work on epigenetic mechanisms of drug resistance and cancer cell dormancy in breast cancer. We start the interview by putting our focus on his significant contributions to the understanding of estrogen receptor-positive breast cancer. In a foundational study from 2013, Professor Magnani and his colleagues illuminated the role of genome-wide reprogramming of the chromatin landscape in conferring resistance to endocrine therapy. This research marked a departure from a purely genetic mutation paradigm, proposing instead that epigenetic modifications play a pivotal role in the development of drug resistance. A fascinating part of our conversation centers on the role of pioneer transcription factors, particularly PBX1, in regulating the estrogen receptor's transcriptional response. Professor Magnani explains how PBX1, typically associated with hematopoietic development, influences estrogen receptor activity, thereby shaping the cancer cell's fate and response to treatment. Continuing our exploration, we discuss the critical distinctions between primary and metastatic breast cancer through the lens of epigenetic reprogramming. By analyzing samples from women with breast cancer, Professor Magnani's work identifies specific enhancer usage that marks the transition to a drug-resistant state which was a breakthrough in linking epigenetic alterations to real-world patient outcomes. He emphasizes that the reliance on genetic mutations alone does not adequately explain the mechanisms of drug resistance, pushing the field to consider the epigenetic landscape more deeply. Our conversation also touches on the evolution of experimental techniques. Professor Magnani shares insights into the transition from traditional ChIP-seq methods to CUT&RUN, demonstrating the need for techniques that cater to the limited material available from clinical samples. This adaptability mirrors the dynamic nature of cancer itself, as cells continuously evolve under therapeutic pressure. As we traverse through the complexities of dormancy and reactivation in cancer cells, Professor Magnani enlightens us on the unpredictable nature of tumor behavior. He describes how cancer cells can enter dormant states and how their awakening is influenced by environmental factors, akin to an evolutionary response to stressors, thus revealing the intricate balance between survival and proliferation. In the latter part of the episode, we explore Professor Magnani's vision for the future of breast cancer research, which includes the need for better animal models that mimic human disease. His pursuit of understanding estrogen receptor behavior both in healthy and cancerous cells reflects a holistic approach to cancer biology, aiming to decipher the transition from normal tissue to malignancy.   References Magnani, L., Stoeck, A., Zhang, X., Lánczky, A., Mirabella, A. C., Wang, T. L., Gyorffy, B., & Lupien, M. (2013). Genome-wide reprogramming of the chromatin landscape underlies endocrine therapy resistance in breast cancer. Proceedings of the National Academy of Sciences of the United States of America, 110(16), E1490–E1499. https://doi.org/10.1073/pnas.1219992110 Nguyen, V. T., Barozzi, I., Faronato, M., Lombardo, Y., Steel, J. H., Patel, N., Darbre, P., Castellano, L., Győrffy, B., Woodley, L., Meira, A., Patten, D. K., Vircillo, V., Periyasamy, M., Ali, S., Frige, G., Minucci, S., Coombes, R. C., & Magnani, L. (2015). Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion. Nature communications, 6, 10044. https://doi.org/10.1038/ncomms10044 Patten, D. K., Corleone, G., & Magnani, L. (2018). Chromatin Immunoprecipitation and High-Throughput Sequencing (ChIP-Seq): Tips and Tricks Regarding the Laboratory Protocol and Initial Downstream Data Analysis. Methods in molecular biology (Clifton, N.J.), 1767, 271–288. https://doi.org/10.1007/978-1-4939-7774-1_15   Related Episodes Enhancers and Chromatin Remodeling in Mammary Gland Development (Camila dos Santos) Contribution of Estrogen Receptor to Breast Cancer Progression (Jason Carroll) Circulating Epigenetic Biomarkers in Cancer (Charlotte Proudhon)   Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com

All in Football FPL Show's Differential King recaps on his Budget Midfielders display on Game week 1 and also picks his Kings for GW2.Do you agree with these selections?Do you have any different?Comment your suggestions to get a shoutout on next weeks show.Don't forget to like and subscribe and give us 5 stars. Hosted on Acast. See acast.com/privacy for more information.

Dr. Benedict Nwachukwu joins host Phil Plisky to take a deep dive into hip impingement and labral tears. With insights shaped by both surgical expertise and personal experience as an athlete, Dr. Ben shares what really drives the decision between rehab and surgery. Together, they unpack how rehab professionals like you can navigate the gray areas with confidence and clarity. Don't miss this thoughtful conversation on what the latest research means for your patients—and your practice.Learning ObjectivesAnalyze the evidence around hip preservation strategiesApply evidence-based, practical strategies to actionably address conservative and postoperative hip joint pathologySolve patient case scenarios involving postoperative hip labral repair and reconstructionTimestamps(00:00:00) Welcome(00:01:25) Introduction to guest(00:03:33) Introduction to hip labral tears and impingement(00:08:13) Understanding hip anatomy and impingement(00:16:30) The interplay of hip and spine(00:22:23) Differential diagnosis of hip conditions(00:25:26) Current research on hip management(00:30:46) Indications for a surgical referral(00:36:07) Postoperative rehabilitation process(00:42:28) Comparisons to ACL reconstruction(00:47:19) Postoperative dos and don'ts(00:55:40) Case study: a journey through hip surgery(00:59:24) Key takeaways and future directionsRehab and Performance Lab is brought to you by Medbridge. If you'd like to earn continuing education credit for listening to this episode and access bonus takeaway handouts, log in to your Medbridge account and navigate to the course where you'll find accreditation details. If applicable, complete the post-course assessment and survey to be eligible for credit. The takeaway handout on Medbridge gives you the key points mentioned in this episode, along with additional resources you can implement into your practice right away.To hear more episodes of Rehab and Performance Lab, visit ⁠⁠⁠⁠https://www.medbridge.com/rehab-and-performance-lab⁠⁠⁠⁠If you'd like to subscribe to Medbridge, visit ⁠⁠⁠⁠https://www.medbridge.com/pricing/

The time for tweaking your squad is almost over, so Kelly Somers and the FPL Pod team are here to give you some last-minute advice

Here it is folks, the third and final installment on our mini-series about building trust! Thank you all so much for your patience, for listening, for learning, that's the attitude to have when entering the communal thought Schauer! We're sharing cognitive load and helping each other co-regulate [somewhat parasocial conclusion redacted for posterity purposes] so thank you. Can't wait to talk to you all next week about something tangentially related. Make sure to like and subscribe on Youtube, as well as rate 5 stars on Spotify or Apple Podcasts! This year, skip breaking a sweat AND breaking the bank. Get this new customer offer and your 3-month Unlimited wireless plan for just 15 bucks a month at https://MintMobile.com/SCHAUER Upfront payment of $45 required (equivalent to $15/mo.). Limited time new customer offer for first 3 months only. Speeds may slow above 35GB on Unlimited plan. Taxes & fees extra. See MINT MOBILE for details. Resources: Four Colors of Lies http://changingminds.org/explanations/behaviors/lying/four_lies.htm An Illustrated Guide to the 4 Types of Liars https://www.nirandfar.com/types-of-liars/ Visual Perception and Corollary Discharge  https://pmc.ncbi.nlm.nih.gov/articles/PMC2807735/#:~:text=Identifying%20a%20corollary%20discharge%20in,Holst%20and%20Mittelstaedt%2C%201950). Propensity to trust and risk aversion: Differential roles in the trust process https://www.sciencedirect.com/science/article/abs/pii/S0092656623000119 Agreeableness https://www.psychologytoday.com/us/basics/agreeableness 12 Proven Trust-Building Exercises to Repair Relationships of All Types https://riveroakspsychology.com/12-proven-trust-building-exercises-to-repair-relationships-of-all-types/ 5 Creative Bullet Journal Mood Tracker Ideas [and Your How To Guide] https://www.yopandtom.com/blogs/news/5-creative-bullet-journal-mood-tracker-ideas-and-your-how-to-guide?srsltid=AfmBOoq1RVxbyYU_8b-31IJzxvrtezmy64Xyp8zdmgBUp3lJnyoyDhto Lying: Moral Choice in Public and Private Life - Sissela Bok The Order of Time - Carlo Rovelli Learn more about your ad choices. Visit podcastchoices.com/adchoices

In this “Best of” edition, host Duane Schulthess revisits two landmark conversations on the long-term impact of the Inflation Reduction Act (IRA) on the biopharmaceutical industry. First, Peter Kolchinsky (Managing Partner, RA Capital Management; Steering Committee Member, No Patient Left Behind), explains why nine-year negotiation timelines for small molecules undermine early-stage R&D and how extending biologics to 13 years still falls short of the “social contract” Congress originally intended. Then, John LaMattina (former President of Pfizer Global R&D; Senior Partner, PureTech Health) discusses how real-world IRA pricing is reshaping pipelines, discovery priorities, and venture capital strategies. Key Topics: IRA negotiation timelines and their effect on R&D decisions Differential price-setting mechanisms: nine years for small molecules vs. 13 years for biologics Patient access challenges under out-of-pocket caps and the case for insurance reform The march-in rights debate and its (limited) practical impact Shifts in VC focus and logical portfolio rebalancing Read our research on the impacts of the IRA: https://vitaltransformation.com/2025/04/inflation-reduction-act-two-years-on-investor-behavior-rd-impacts-proposed-solutions/ Originally broadcast Jan 17, 2024 and Mar 27, 2024. Edited and compiled Aug 2025. Opinions expressed are those of the speakers.See omnystudio.com/listener for privacy information.

After a busy week of tinkering with our first squad drafts, Kelly Somers and the FPL Pod team are back to look over their changes and chat about which premiums to pick ♻️

In this episode of Breaking Math, Autumn explores the complex world of AI ethics, focusing on its implications in education, the accuracy of AI systems, the biases inherent in algorithms, and the challenges of data privacy. The discussion emphasizes the importance of ethical considerations in mathematics and computer science, advocating for transparency and accountability in AI systems. Autumn also highlights the role of mathematicians in addressing these ethical dilemmas and the need for society to engage critically with AI technologies.Takeaways AI systems can misinterpret student behavior, leading to false accusations. Bias in AI reflects historical prejudices encoded in data. Predictive analytics can help identify at-risk students but may alter their outcomes. Anonymization of data is often ineffective in protecting privacy. Differential privacy offers a way to share data while safeguarding individual identities. Ethics should be a core component of algorithm design. The impact of biased algorithms can accumulate over time. Mathematicians must understand both technical and human aspects of AI. Society must question the values embedded in AI systems. Small changes in initial conditions can lead to vastly different outcomes.Chapters 00:00 Introduction to AI Ethics 02:14 The Accuracy and Implications of AI in Education 04:14 Bias in AI and Its Consequences 05:45 Data Privacy Challenges in AI 06:37 Mathematical Solutions for Ethical AI 08:04 The Role of Mathematicians in AI Ethics 09:42 The Future of AI and Ethical ConsiderationsSubscribe to Breaking Math wherever you get your podcasts.Become a patron of Breaking Math for as little as a buck a monthFollow Breaking Math on Twitter, Instagram, LinkedIn, Website, YouTube, TikTokFollow Autumn on Twitter and InstagramBecome a guest hereemail: breakingmathpodcast@gmail.com

Graeme Findlay visits the swamp and brings his Differential Voice leadership meta-model. Graeme makes the case that to lead effectively today, a leader needs more than one voice.  Graeme has us covered: his differential voice approach is based on six major ‘modes' of leading. Take note as Graeme leads us through when and how we use these different leadership voices.Graeme's LinksWebsiteDifferential VoiceBlogLeadership ProgrammeThanks for listening. Send me your feedbackI want to thank my great team that helps me sound better than I am. Jacki Hydock for her lending her wonderful voice to our introduction and outro Great music by Jazz Night Awesome episode production by the great team of We Edit Podcasts all the way up in Calgary, Alberta, Canada. Check them out at www.weeditpodcasts.com Thanks For Listening and Jumping into the Swamp

Guest: Blue Jays outfielder Nathan Lukes   The Blue Jays have swept their way into first place by beating the New York Yankees four straight – the first time that has ever happened in Toronto. The Jays scored 36 runs over the four-game sweep, coming from behind twice and rebounding from blowing an eight-run lead once, in four intense games in an incredible atmosphere at Rogers Centre.   Since May 27, the Jays are 23-10 – tied with the Houston Astros for the best record in the major leagues over that span – and they have turned an eight-game deficit in the division into a one-game lead. It's the first time they've been in first place outside the first three weeks of a season since 2016.   Nathan Lukes put the Jays on top to stay in Thursday's finale with a two-run double that ended an epic 14-pitch at-bat. The Jays' leadoff man - for that game, anyway - joins us to talk about that big hit and more!

Jeff Blair and Kevin Barker kick off the second hour with reaction to the All-Star teams, with Vladimir Guerrero Jr. getting the honour for a fifth time. ESPN MLB insider Jeff Passan (3:24) stops by to discuss MLB's gambling investigation on Luis Ortiz, the Jays' place atop the AL East despite a meagre run differential, and their chances at holding on to the division lead through this season. Later, Yankees analyst Pete Caldera (25:55) helps tee up the series finale between the Yanks and Blue Jays and discusses what Brian Cashman will need to prioritise at the trade deadline, whether this is the best version of Aaron Judge and the team's future at shortstop.The views and opinions expressed in this podcast are those of the hosts and guests and do not necessarily reflect the position of Rogers Sports & Media or any affiliates.

The capabilities of artificial intelligence may appear to be galloping ahead, but there are still many challenges that need to be solved. Last month we joined members of the Maths4DL research project for a hackathon — an intensive two-day brainstorming session designed to figure out how one might teach machine learning techniques for solving differential equations and how best to test those techniques. In this episode of Maths on the Move, Maths4DL members Yolanne Lee from University College London, Georg Maierhofer from the University of Cambridge, and Chris Budd OBE from the University of Bath tell us all about the hackathon, the science behind it, and what it was like to participate in those ambitious but exciting 48 hours. For a brief introduction to machine learning see Maths in a minute: Machine learning and neural networks and for a brief introduction to differential equations see Maths in a minute: Differential equations. You might also like: Our podcast featuring Yolanne Lee talking about her work as a Maths4DL researcher, Our podcast featuring Georg Maierhofer talking about physics informed neural networks, as well as the accompanying article, Our article AI and GoPro physics featuring the work of Nathan Kutz who is mentioned in this podcast. This content is part of our collaboration with the Mathematics for Deep Learning (Maths4DL) research programme, which brings together researchers from the universities of Bath and Cambridge, and University College London. Maths4DL aims to combine theory, modelling, data and computation to unlock the next generation of deep learning. You can see more content produced with Maths4DL here.

92.9 The Game Atlanta Braves Insider and From The Diamond Host Grant McAuley talks about defending the Braves calling themselves a good team with a bad record, having to find some footing before starting to build back up, how the team should have avoided what happened with Craig Kimbrel, what is the plan at closer moving forward, and what the role might be for Jose Ruiz.

As an awesome Premier League campaign comes to a close, we look back on a rollercoaster FPL season and hand out our inaugural #FPLPodAwards

The Chicago Cubs lead MLB in run differential, but is it sustainable long-term? We break down Pete Crow-Armstrong's breakout, Kyle Tucker's red-hot week, and Matt Shaw's impressive emergence in the Cubs' lineup. With bullpen injuries piling up, Cade Horton and other young arms are being thrown into high-leverage roles. Tune in as the CHGO Cubs crew analyzes what's real, what's not, and what's next for this red-hot Cubs team.

In this episode with Dr Stacey Hardin, we explore an interesting case study of a 25 year old soccer player who sustained a groin injury during match play. We cover:Subjective historyOn-field examination Differential diagnosis within this body areaObjective historySurgical vs conservative management Role of MRI in the management of this injuryRole of multidisciplinary managementDr Stacey Hardin is a physical therapist and athletic trainer based in the United States. She has worked in elite soccer for over 10 years and currently works as the Director of Medical for Bay FC. In addition to her work in professional soccer, Hardin is actively involved in applied research and education.If you like the podcast, it would mean the world if you're happy to leave us a rating or a review. It really helps!Our host is @James_Armstrong_Physio from Physio Network

Two of the most popular players in the game this season are being shipped out as returns dwindle and managers try some bold moves to finish as high as possible in the rankings

Erling Haaland is expected to come back and get some minutes against a relegated Southampton side this Gameweek, but for how long no-one is sure, which is causing concern

Dr. Bill Ahearn joins me in Session 299 of Behavioral Observation. I met Bill a few times at conferences and I'm so glad we finally had a chance to sit down and record a podcast together. Bill is the Director of Research at The New England Center for Children. Long time listeners may recall that NECC sponsored a series of episodes, and in this podcast, we talked about some of the great research that has come out of that storied institution. As an aside, if you want to learn more about NECC, particularly working at NECC, you can find more information about that here. We covered a lot of ground in this conversation, including: Bill's early experiences as a grad student and clinician. His early work in addressing feeding problems. The research that he and his colleagues have conducted at NECC. How he construes stereotypic and self-injurious behavior as being forms of repetitive behavior. What he's learned about addressing stereotypy, including when and when not to intervene. We talk at length about Response Interruption and Redirection, particularly when it is and isn't necessary as an intervention. The behavioral interpretation of anxiety, and interventions that he and his team have brought to bear on related repertoires. I ask a few lighter questions on some topics of mutual interest (you'll have to listen towards the end to hear that). If you listen to nothing else from this podcast, towards the end of the show, Bill talks about why he is proud to be a Behavior Analyst. Please listen to that segment, as I think he makes some excellent points that are more than worth sharing. We also talked about tons of papers. I've done my best to track as many down as possible. Piazza et al. (2000). An evaluation of the effects of matched stimuli on behaviors maintained by automatic reinforcement. Rapp and Vollmer (2005). Stereotypy I: A review of behavioral assessment and treatment. Ahearn et al. (2007). Assessing and treating vocal stereotypy in children with autism. Colón et al. (2012). The effects of verbal operant training and response interruption and redirection on appropriate and inappropriate vocalizations. Rodriguez et al. (2013). Arranging and ordering in autism spectrum disorder: Characteristics, severity, and environmental correlates. Steinhauser et al. (2021). Examining stereotypy in naturalistic contexts: Differential reinforcement and context-specific redirection. Moore et al. (2022). Assessing and Treating Anxiety in Individuals with Autism. Fergus (2024). Functional Analysis and Delineating Subtypes of Restricted Repetitive Behavior in Individuals with Autism Spectrum Disorder. This podcast is brought to you by: Frontera. Consider taking a demo of Frontera's Assessment Builder and see how the ethical application of AI technologies can help you serve clients and save you time! Your first assessment report is free. And if you use code BOP25 you'll get an additional five assessments for just $100. So head to fronterahealth.com to check it out! CEUs from Behavioral Observations. Learn from your favorite podcast guests while you're commuting, walking the dog, or whatever else you do while listening to podcasts. New events are being added all the time, so check them out here.  The Behavioral Toolbox. Check out our courses for school-based and other behavioral professionals, including our newest one, Motivational Interviewing: Getting Educator Buy-In. Behavior University. Their mission is to provide university quality professional development for the busy Behavior Analyst. Learn about their CEU offerings, including their 8-hour Supervision Course, as well as their RBT offerings over at behavioruniversity.com/observations. Don't forget to use the coupon code, PODCAST to save at checkout!

As Evan Petzold returns from paternity leave, the Detroit Tigers hold the best record in the American League (22-13) and lead MLB with a plus-63 run differential through 35 games in the 2025 season. They've also launched a league-leading 20 home runs since April 28, doing so in the first seven games of their 10-game road trip. What has stood out most over the first 35 games? And what should we expect from Javier Báez moving forward? Tigers radio analyst Bobby Scales joins the Days of Roar podcast to break down Detroit's early success, hitting coach Michael Brdar's game planning, and how opposing pitchers are adjusting to Spencer Torkelson, plus he shares his take on Báez's resurgence.To close the show, Evan and Mark Gorosh analyze the Tigers' decision to cut struggling pitcher Kenta Maeda, share injury updates and debate a key question: Which former No. 1 overall pick inspires more confidence — Spencer Torkelson or Casey Mize? Follow Evan on X/Twitter here. Read Evan's most recent work here

With just four matches left of the season, it's now or never if you want to go big and climb the rankings

Just as back-to-back Double Gameweeks end, FPL managers now have Blank Gameweek 34 to navigate, and lots of Free Hit chips are expected to be played

Ever wonder what our live leadership development workshops are like? This episode is a short clip of a live workshop we put on a couple of months ago. If you sign up for this online workshop series, use this code at checkout to get a 25% discount: MINDANDHEARTPOD We edited out any voices of participants, plus all the group work, breakout rooms, and Q/A, so you'll just hear Ethan. In this episode, Ethan discusses the power differential: what it is, what it's made of, and how to moderate it. 

This post elaborates on the sensitivity research section of The HSP Owner's Guide. Differential susceptibility is a key concept in high-sensitivity research. In simple terms, it means that the more sensitive you are, the more your environment impacts you. As a highly sensitive person (HSP), you might notice that some people thrive in situations where you feel discombobulated. Conversely, when conditions feel right, you may experience more intense joy, connection, and growth than others. It's the idea that some people are more responsive to their environment—for better or worse. For HSPs, this heightened responsiveness is a defining trait linked to their depth of processing, shaping how they experience life. However, it's important to remember that not all HSPs are the same. Sensitivity is just one part of who we are, and how we respond to our environments can vary widely. https://youtu.be/GIIKRuy5TOw What is Differential Susceptibility? Differential susceptibility means that the more sensitive someone is, the more influence their environment has on them. We might think of it like a spectrum of responsiveness. On one end, some people are like sturdy structures, able to adapt to a wide range of conditions without much change. On the other hand, many HSPs are finely tuned instruments that process their environment in depth. This can allow them to thrive in supportive settings but may also make them more vulnerable in harsh ones. For many HSPs, this means they are deeply affected by their upbringing, current environment, and the people around them. In favourable conditions, they may flourish more intensely than others, finding creative flow, experiencing strong empathy, and having deep insights. In unfavourable conditions, they might struggle more than others, feeling overstimulated or drained, unable to utilise the and share the fruits of their high sensitivity. This heightened responsiveness isn't a weakness—it's a unique way of engaging with the world that comes with challenges and strengths. That said, again to reiterate, not all HSPs will respond the same way. Sensitivity interacts with other aspects of personality, life experiences, and individual differences. How Does Differential Susceptibility Shape Our Lives? Differential susceptibility shows up in tangible ways for many HSPs. Here's how it might play out, maybe you recognise your own experiences in these examples: Growing Up: The Impact of Early Environments Supportive Upbringing: If an HSP grows up in a nurturing environment—where their sensitivity is understood and valued—they are more likely to develop strong emotional intelligence, creativity, and resilience. Challenging Upbringing: If an HSP grows up in a less supportive environment—where their sensitivity was dismissed or criticised—they might have learned to hide their true self, leading to feelings of disconnection or self-doubt. For example, imagine an HSP who grew up in a chaotic and unpredictable household. If there is constant noise or tension, that person's nervous system is more likely to be dysregulated, overstimulated and seeking safety from unsafe sources. They may assume the "tiny adult" role, feeling responsible for trying to keep the environment 'in balance' by fawning, people pleasing, monitoring moods (over empathy). But if that same HSP had grown up in a calm, supportive home, they might have thrived, using their sensitivity to connect deeply with others and appreciate life's beauty. Adulthood: Creating Nurturing Environments Favourable Conditions: When HSPs are in environments that honour their sensitivity—like a peaceful home, a supportive workplace, or a close-knit community—they often bring incredible strengths. They may notice what others miss, create spaces of warmth and connection, and approach challenges creatively and empathetically. Unfavourable Conditions: In overwhelming or unsupportive environments—like a stressful job,

The Double Gameweek fun continues with four teams playing twice and big points on offer for excited managers

Has Claude by Anthropic lost its edge in AI? Discover why OpenAI and Google are pulling ahead and what it means for AI dominance. Explore if Claude can stage a comeback and what's next for AI innovation. Tune in for insights and analysis.Newsletter: Sign up for our free daily newsletterMore on this Episode: Episode PageJoin the discussion: Thoughts on this? Join the convo.Upcoming Episodes: Check out the upcoming Everyday AI Livestream lineupWebsite: YourEverydayAI.comEmail The Show: info@youreverydayai.comConnect with Jordan on LinkedInTopics Covered in This Episode:Anthropic's Claude Losing Market EdgeComparison of AI Innovators: Anthropic vs. GoogleClaude 3.7 and Industry RelevanceOpenAI and Google AI AdvancementsEnterprise Hesitation with Anthropic's ClaudeBenchmark Performance: Anthropic vs. CompetitionClaude User Experience and Rate LimitsFuture Prospects for Anthropic and ClaudeTimestamps:00:00 Anthropic's Decline in AI Race02:20 Daily AI News10:00 Has Anthropic Claude Lost It's Edge?17:05 Claude's Restrictive Approach Missteps20:50 Anthropic's Delayed Feature Rollout22:17 Claude's Profitability vs. User Growth27:42 Can Anthropic Stay Competitive?30:02 Anthropic's Struggle Against Gemini Models32:57 "Claude's Ranking Below Top 10"36:08 Coding Model Rankings: OpenAI Tops40:46 "Claude's Decline Amidst AI Advancements"44:00 "Frustration Over Usage Limitations"48:33 Anthropic Lags Behind Google/OpenAI49:10 "Stay Connected & Engaged"Keywords:Anthropic, Claude, Claude 3.7, Claude's edge, AI model, Large Language Model, AI frontier labs, Google, OpenAI, Microsoft, Apple, Synthetic data, Differential privacy, Tariff policies, NVIDIA, U.S. AI manufacturing, Taiwan Semiconductor, Foxconn, Wistron, Digital twins, Advanced robotics, GPT 4.1, Million token context window, API developers, Context processing, Claude's competitiveness, Internet access, Third-party integrations, Rate limits, Claude artifacts, Claude projects, Computer use, Power users, AI safety, Claude Max, Rate limit sessions, Cloud recovery, AI coding index, Coding performance, Price comparison, Benchmark performance, Intelligence index, Human preference, Elo score, Web traffic, Market competition, Enterprise challenges.Send Everyday AI and Jordan a text message. (We can't reply back unless you leave contact info) Ready for ROI on GenAI? Go to youreverydayai.com/partner

For generations, women have been systematically taught to forget their inner intelligence. Patriarchal systems have consistently reinforced the notion that the male perspective is inherently correct. This disconnection from our own wisdom has profound consequences: we mistake silence for righteousness, shrink ourselves and call it humility, endure emotional pain and label it patience. When opportunities pass us by because of these learned limitations, it appears to validate the oppressor's claim that women are somehow less capable.The painful truth is that patriarchy thrives on hierarchy. It's built on the belief that someone must occupy the top position while another remains beneath—a dynamic that contradicts the Islamic vision of marriage as a mutual agreement and source of peace. When we're told repeatedly that our worth is connected to having successful relationships or bearing children, we begin to believe our value exists only in relation to others. But your worth remains 100% whole whether you're married, single, divorced, or childless. You are worthy because Allah created you worthy—no hierarchy can add to that, no relationship can validate it, no absence of a partner can diminish it.Healing begins with awareness and giving your experiences language. It requires recognizing this isn't about your personality flaws, but about socialized patterns. My work isn't about convincing anyone of their worth, but helping them remember what they've always been. Whether through coaching, reading, journaling, or whatever tools speak to you, don't wait for someone else's growth before reclaiming your power.Want to get coached by me? Wisdom Wednesdays is the most sacred space online for married Muslim women to build confidence, intimacy, and connection, with full Islamic adab, total privacy, and zero judgment.This isn't a course. It's live, interactive coaching at just $19.99/month, the cost of one takeout dinner.Enrollment is open April 3–16, 2025.https://www.islami

It's the first of two back-to-back Double Gameweeks as Newcastle and Crystal Palace play twice

It's a huge Gameweek for activating chips as managers look to use their Wildcard or Assistant Manager following the announcement of Double Gameweek 33

I'm back, baby. I've been away traveling for podcasts and am excited to bring you new ones with Michael Levin, William Hahn, Robin Hanson, and Emily Riehl, coming up shortly. They're already recorded. I've been recovering from a terrible flu but pushed through it to bring you today's episode with Urs Schreiber. This one is quite mind-blowing. It's quite hairy mathematics, something called higher category theory, and how using this math (which examines the structure of structure) allows one manner of finding "something" from "nothing." Here, "nothing" means the empty set, and "something" is defined as fermions and even 11D supergravity. It's the first time this material has been presented in this manner. Enjoy. NOTE: Link to technical details are here from Urs Schreiber: https://ncatlab.org/schreiber/show/Peri+Pantheorias As a listener of TOE you can get a special 20% off discount to The Economist and all it has to offer! Visit https://www.economist.com/toe Join My New Substack (Personal Writings): https://curtjaimungal.substack.com Listen on Spotify: https://tinyurl.com/SpotifyTOE Become a YouTube Member (Early Access Videos): https://www.youtube.com/channel/UCdWIQh9DGG6uhJk8eyIFl1w/join Links Mentioned: - nLab website: https://ncatlab.org/nlab/show/HomePage - Paper on category theory: https://people.math.osu.edu/cogdell.1/6112-Eilenberg&MacLane-www.pdf - “Higher Topos Theory for Physics” (Urs's talk): https://www.youtube.com/watch?v=GD20W6vxMI4 - “Higher Topos Theory for Physics” (Urs's paper): https://arxiv.org/pdf/2311.11026 - Stephen Wolfram on TOE: https://www.youtube.com/watch?v=0YRlQQw0d-4 - Feynman's thesis: https://faculty.washington.edu/seattle/physics541/2012-path-integrals/thesis.pdf - Differential cohomology in a cohesive ∞-topos (Urs's paper): https://arxiv.org/pdf/1310.7930 - M-Theory from the Superpoint (paper): https://arxiv.org/pdf/1702.01774 - Character Map in Non-Abelian Cohomology, The: Twisted, Differential, and Generalized (textbook): https://amzn.to/4bFuz7H - TOE's String Theory Iceberg: https://www.youtube.com/watch?v=X4PdPnQuwjY Timestamps: 00:00 Introduction 01:27 The Creation of nLab 04:36 Philosophy Meets Physics 07:55 The Role of Mathematical Language 09:32 Emergence from Nothing 16:25 Towards a Theory of Everything 22:21 The Problem with Modern Physics 25:31 Diving into Category Theory 35:30 Understanding Adjunctions 41:46 The Significance of Duality 52:54 Exploring Toposes 1:14:20 The UNEDA Lemma and Generalized Spaces 1:16:37 Charts in Physics 1:20:55 Introduction to Infinitesimal Disks 1:23:56 The Emergence of Supergeometry 1:27:33 Transitioning to Gauge Theories 1:28:11 Exploring Singularities in Physics 1:32:50 The Role of Superformal Spaces 1:36:44 Functors and Their Implications 1:40:51 From Nothing to Emergent Structures 1:43:04 Hegel's Influence on Modern Physics 1:54:07 Discovering Higher-Dimensional Structures 1:56:30 The Path to 11-Dimensional Supergravity 1:57:21 Universal Central Extensions 2:03:21 The Journey to M-Theory 2:11:19 Globalizing the Structure of Supergravity 2:15:36 Understanding Global Charges in Physics 2:23:31 Dirac's Insights into Gauge Potentials 2:30:21 The Quest for Non-Perturbative Physics 2:39:04 Conclusion Support TOE on Patreon: https://patreon.com/curtjaimungal Twitter: https://twitter.com/TOEwithCurt Discord Invite: https://discord.com/invite/kBcnfNVwqs #science #theoreticalphysics Learn more about your ad choices. Visit megaphone.fm/adchoices

Your brand name isn't just a name: it's your gateway to capital, credibility, and growth! From culture shock to capital gains, your brand could be the key to unlocking major opportunities or keeping you stuck in the hustle. In this masterclass episode Part 2 with branding expert Evante Daniels, we break down the branding science Black businesses need to succeed!We dive deep into:Why your brand name can be the difference between getting funded or forgottenThe two ways to create demand (and why most fail)How to position your brand for growth without losing cultural authenticityThe branding mistakes that cost Black businesses capital and credibilityThe power of strategic naming, perception, and Cultural IP in breaking business barriersThink about how Beyoncé built an empire, how Nike's branding made them legendary, and how companies like Apple and Adidas have mastered the art of brand perception. These aren't just names—they're strategic assets rooted in Cultural IP, market psychology, and identity positioning that drive influence and revenue.If you want to elevate your brand beyond the culture and into boardrooms, bank accounts, and billion-dollar opportunities, this episode is for you. Too often, Black entrepreneurs brand based on passion rather than positioning. But your brand must speak the language of capital if you want to break barriers and build generational wealth. If you're serious about turning your culture into capital and your brand into a business that thrives, and not just survives, this episode is a must-listen.Listen to Part 1 of our conversation here.Beyond The Episode Gems:Follow Evante Daniels On LinkedIn For Creative & Brand Insights, Strategy, Content, & MemesInterested In Working With Evante and Seeqer? Visit Seeqer Website For Services, Case Studies, & Getting StartedBuy Evante's Book "Power, Beats, & Rhymes: Reclaiming Our Cultural Voice"Subscribe To My New Weekly LinkedIn Newsletter: Strategize. Market. Grow.Buy My Book, Strategize Up: The Blueprint To Scale Your Business: StrategizeUpBook.comDiscover All Podcasts On The HubSpot Podcast NetworkTry GetResponse For FREE On Me To Monetize Your Content: GetResopnse Content Monetization Plan Support The Podcast & Connect With Troy: Rate & Review iDigress: iDigress.fm/ReviewsFollow Troy's LinkedIn @FindTroyNeed Growth Strategy, A Keynote Speaker, Or Want To Sponsor The Podcast? Go To FindTroy.comFollow Troy's Instagram @FindTroySubscribe to Troy's YouTube Channel 

Branding is NOT just your logo, colors, or typography. It is perception. It is how people see you, interpret you, and experience you.In this masterclass episode, creative strategist and brand expert Evante Daniels, CSO & Founder of Seeqer, breaks down his biggest branding pet peeves, why marginal market differentiation is the key to success, and how trying to be too different can actually hurt your brand. If your brand stands out more than 5% from the standard, you risk losing connection with your audience. Think of it like seasoning—too much, and no one wants to eat it.We dive into brand standards, color theory, market framing, positioning, and consumer psychology to help you build a brand that resonates while infusing culture to influence brand perception to expand community and loyalty. You do not need to reinvent everything. You need to find your lane. Your brand should reflect who you are becoming, not just where you are today.It is not about faking it until you make it. It is about positioning yourself with passion, potential, and power.This is Part 1 of a must-listen branding conversation.Beyond The Episode Gems:Follow Evante Daniels On LinkedIn For Creative & Brand Insights, Strategy, Content, & MemesInterested In Working With Evante and Seeqer? Visit Seeqer Website For Services, Case Studies, & Getting StartedBuy Evante's Book "Power, Beats, & Rhymes: Reclaiming Our Cultural Voice"Subscribe To My New Weekly LinkedIn Newsletter: Strategize. Market. Grow.Buy My Book, Strategize Up: The Blueprint To Scale Your Business: StrategizeUpBook.comDiscover All Podcasts On The HubSpot Podcast NetworkTry GetResponse For FREE On Me To Monetize Your Content: GetResopnse Content Monetization Plan Support The Podcast & Connect With Troy: Rate & Review iDigress: iDigress.fm/ReviewsFollow Troy's LinkedIn @FindTroyNeed Growth Strategy, A Keynote Speaker, Or Want To Sponsor The Podcast? Go To FindTroy.comFollow Troy's Instagram @FindTroySubscribe to Troy's YouTube Channel