Podcasts about The New England Journal of Medicine

Peer-reviewed medical journal

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    Best podcasts about The New England Journal of Medicine

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    Latest podcast episodes about The New England Journal of Medicine

    NEJM This Week — Audio Summaries
    NEJM This Week — February 2, 2023

    NEJM This Week — Audio Summaries

    Play Episode Listen Later Feb 1, 2023 32:10


    Featuring articles on baxdrostat for treatment-resistant hypertension, VV116 versus nirmatrelvir for Covid-19, hypothermia or machine perfusion in kidney donors, effectiveness of the 4CMenB vaccine in children, implications of the 2022 election for health policy, and animal models and psychedelic research; a review article on innate immunity; a Clinical Problem-Solving on a breathtaking discovery; and Perspective articles on facing the new Covid-19 reality and on equity in global health research.

    Saving Lives: Critical Care w/eddyjoemd
    More Fluids vs. Vasopressors During the First 24 Hours of Septic Shock (CLOVERS Trial)

    Saving Lives: Critical Care w/eddyjoemd

    Play Episode Listen Later Jan 29, 2023 19:03


    Show Notes: Coming Soon! TrueLearn Link: https://truelearn.referralrock.com/l/EDDYJOEMD25/Discount code: EDDYJOEMD25 Citation: National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury Clinical Trials Network; Shapiro NI, Douglas IS, Brower RG, Brown SM, Exline MC, Ginde AA, Gong MN, Grissom CK, Hayden D, Hough CL, Huang W, Iwashyna TJ, Jones AE, Khan A, Lai P, Liu KD, Miller CD, Oldmixon K, Park PK, Rice TW, Ringwood N, Semler MW, Steingrub JS, Talmor D, Thompson BT, Yealy DM, Self WH. Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension. N Engl J Med. 2023 Jan 21. doi: 10.1056/NEJMoa2212663. Epub ahead of print. PMID: 36688507. --- Support this podcast: https://anchor.fm/eddyjoemd/support

    NEJM This Week — Audio Summaries
    NEJM This Week — January 26, 2023

    NEJM This Week — Audio Summaries

    Play Episode Listen Later Jan 25, 2023 25:59


    Featuring articles on extracorporeal CPR for cardiac arrest, efanesoctocog alfa in severe hemophilia A, zanubrutinib in chronic lymphocytic leukemia, and on using rescaled cystatin C to estimate GFR; a review article on antiretroviral therapy and adverse pregnancy outcomes; a case report of a girl with abdominal pain and bloody diarrhea; and Perspective articles on regulating reproductive medicine without Roe, on sources of innovation in gene therapies, and on the promise.

    New England Journal of Medicine Interviews
    NEJM Interview: Dr. Julianne Holt-Lunstad on the association between social connection and health.

    New England Journal of Medicine Interviews

    Play Episode Listen Later Jan 18, 2023 10:44


    Dr. Julianne Holt-Lunstad is a professor of psychology and neuroscience at Brigham Young University Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. J. Holt-Lunstad and C. Perissinotto. Social Isolation and Loneliness as Medical Issues. N Engl J Med 2023;388:193-195.

    New England Journal of Medicine Interviews
    Weighing the Protective Value of Covid-19 Infection

    New England Journal of Medicine Interviews

    Play Episode Listen Later Jan 18, 2023 20:34


    Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, L.R. Baden, and S. Morrissey. Audio Interview: Weighing the Protective Value of Covid-19 Infection. N Engl J Med 2023;388:e13.

    NEJM This Week — Audio Summaries
    NEJM This Week — January 19, 2023

    NEJM This Week — Audio Summaries

    Play Episode Listen Later Jan 18, 2023 32:42


    Featuring articles on aspirin or heparin thromboprophylaxis after a fracture, omicron neutralization with a bivalent vaccine boost, futibatinib for intrahepatic cholangiocarcinoma, and psychosocial functioning in transgender youth; a review article on periprosthetic joint infection; a case report of a man with dizziness and altered mental status; and Perspective articles on social isolation and loneliness as medical issues, on Medicare overpayment for outpatient medication, on being better off at home, and on hope after firearm trauma.

    Rheuminations
    Making Sense of Sensory Ganglionopathies, Part 2

    Rheuminations

    Play Episode Listen Later Jan 18, 2023 29:24


    In this episode, Dr. Benjamin Claytor walks us through his approach to suspected sensory ganglionopathies. I also cover other neurologic complications of Sjogren's syndrome and some interesting history on vitamin B6. Intro 0:12 In this episode 0:46 Neurologic complications of Sjogren's Syndrome 1:55 Intro of Dr. Benjamin Claytor 6:00 The interview 6:49 Case study: process of diagnosis 7:17 Dorsal root ganglion in Sjogren's 10:46 Facial numbness in sensory ganglionopathies 11:42 Dorsal root ganglion biopsies 13:36 Prognosis of sensory ganglionopathies vs other distal neuropathies 14:03 Sensory loss and weakness 15:51 Sensory ataxia 16:24 Attacks on the dorsal root ganglion 18:25 Loss of fibers in the dorsal root ganglion and regrowth 19:21 Treating cancer and sensory ganglionopathies 20:03 Idiopathic patients and treatments 20:45 Interview wrap-up 21:43 Pearls of wisdom from the interview 22:11 History of sensory ganglionopathies 23:35 Thanks 29:09 Disclosures: Brown and Claytor report no relevant financial disclosures. Benjamin Claytor, MD, is assistant professor of neurology at the Neuromuscular Center at Cleveland Clinic. We'd love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum. References: Antopol W, et al. J Neuropathol Exp. 1942;doi:10.1097/00005072-194207000-00006. Pavlakis PP, et al. J Autoimmun. 2012;doi:10.1016/j.jaut.2012.01.003. Schaumburg H, et al. N Engl J Med. 1983;doi:10.1056/NEJM198308253090801.

    New England Journal of Medicine Interviews
    Covid-19 Vaccines and New Viral Variants

    New England Journal of Medicine Interviews

    Play Episode Listen Later Jan 11, 2023 19:41


    Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, L.R. Baden, and S. Morrissey. Audio Interview: Covid-19 Vaccines and New Viral Variants. N Engl J Med 2023;388:e8.

    NEJM This Week — Audio Summaries
    NEJM This Week — January 12, 2023

    NEJM This Week — Audio Summaries

    Play Episode Listen Later Jan 11, 2023 29:12


    Featuring articles on the progression of atrial fibrillation after cryoablation, empagliflozin in chronic kidney disease, repeat expansion in late-onset cerebellar ataxia, and the safety of inpatient health care; a review article on primary ovarian insufficiency; a case report of a man with hypokalemia and paranoia; and Perspective articles on the anchor strategy and on corporate investors in primary care.

    NEJM This Week — Audio Summaries

    “Intention to Treat,” hosted by health care journalist Rachel Gotbaum, draws on the world-class expertise of the New England Journal of Medicine to present breaking news and incisive analysis of critical and timely issues in medicine and health care. Through interviews with NEJM editors, specialized experts, physicians, and affected patients, each episode explores a story-behind-the-story, giving listeners needed context and a deeper understanding of complex research, cutting-edge medical interventions, and urgent health policy debates that affect patients and the clinicians who care for them. Practicing clinicians, biomedical researchers, medical trainees, patients, and anyone with an interest in health will find unique insights in “Intention to Treat.”

    New England Journal of Medicine Interviews
    NEJM Interview: Dr. David Ansell and Redia Holman on an approach for health care institutions to build community health and wealth.

    New England Journal of Medicine Interviews

    Play Episode Listen Later Jan 11, 2023 17:26


    David Ansell is the senior vice president for community health equity at Rush University Medical Center. Redia Holman is a patient care navigator at Rush University Medical Center and was the chairperson of the West Side employee resource group created as part of Rush's anchor strategy. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. D.A. Ansell and Others. The Anchor Strategy — A Place-Based Business Approach for Health Equity. N Engl J Med 2023;388:97-99.

    HelixTalk - Rosalind Franklin University's College of Pharmacy Podcast
    159 - A Breath of Fresh Air: Big Changes to the 2023 GOLD Guidelines for COPD

    HelixTalk - Rosalind Franklin University's College of Pharmacy Podcast

    Play Episode Listen Later Jan 10, 2023 38:45 Very Popular


    In this episode, we highlight important changes to the 2023 GOLD Guidelines for COPD. In particular, we discuss a revision to the GOLD group classification system and the preferred initial therapies in patients with COPD. Key Concepts The newest GOLD COPD guidelines now recognize three GOLD groups – “A”, “B”, and “E”. Group “E” (formerly groups C and D) are patients with frequent exacerbations (defined as 2 or more in the past 12 months or 1 exacerbation requiring hospitalization). For group “E” patients, the preferred initial inhaler regimen is a LABA+LAMA. Triple therapy (LABA+LAMA+ICS) can be considered if blood eosinophils are elevated. “Triple therapy” (LABA+LAMA+ICS) has gained traction based on the IMPACT and ETHOS trials – this regimen reduced exacerbations and mortality compared to LABA+LAMA and LABA+ICS. With an exploding market of new COPD inhalers, the role of the pharmacist is even more critical to help identify affordable medications and provide patient education for proper inhaler technique. References Global Strategy for Prevention, Diagnosis, and Management of COPD: 2023 Report. Global Initiative for Chronic Obstructive Lung Disease (GOLD). https://goldcopd.org/2023-gold-report-2/ IMPACT study: Lipson DA, Barnhart F, Brealey N, et al. Once-Daily Single-Inhaler Triple versus Dual Therapy in Patients with COPD. N Engl J Med. 2018;378(18):1671-1680. doi:10.1056/NEJMoa1713901 ETHOS study: Rabe KF, Martinez FJ, Ferguson GT, et al. Triple Inhaled Therapy at Two Glucocorticoid Doses in Moderate-to-Very-Severe COPD. N Engl J Med. 2020;383(1):35-48. doi:10.1056/NEJMoa1916046

    Emergency Medical Minute
    Podcast 843: Commotio Cordis

    Emergency Medical Minute

    Play Episode Listen Later Jan 9, 2023 4:50


    Contributor: Jared Scott, MD Educational Pearls: Commotio cordis is sudden ventricular fibrillation precipitated by direct impact to the chest  A national registry, US Commotio Cordis Registry, reports an average of 10-20 cases annually  95% of reported cases occur in males, indicating possible genetic component  Average age of patient in registry is 15  Most cases occur during sporting events (baseball in particular), in addition to physical altercations and industrial accidents  Treatment is high quality CPR and early defibrillation  Survival rate is improving but remains around 35%  In recent events, American football player Damar Hamlin survived a Commotio cordis event after being tackled on field and receiving CPR  References Link MS. Commotio cordis: ventricular fibrillation triggered by chest impact-induced abnormalities in repolarization. Circ Arrhythm Electrophysiol. 2012;5(2):425-432. doi:10.1161/CIRCEP.111.962712 Maron BJ, Poliac LC, Kaplan JA, Mueller FO. Blunt impact to the chest leading to sudden death from cardiac arrest during sports activities. N Engl J Med. 1995;333(6):337-342. doi:10.1056/NEJM199508103330602   Summarized by Kirsten Hughes, MS4 | Edited by John Spartz, MD, & Erik Verzemnieks, MD   The Emergency Medical Minute is excited to announce that we are now offering AMA PRA Category 1 credits™ via online course modules. To access these and for more information, visit our website at https://emergencymedicalminute.org/cme-courses/ and create an account. 

    NEJM This Week — Audio Summaries
    NEJM This Week — January 5, 2023

    NEJM This Week — Audio Summaries

    Play Episode Listen Later Jan 4, 2023 29:28 Very Popular


    Featuring articles on a monoclonal antibody for early Alzheimer's disease, risk assessment for patients with heart failure, RAS inhibition in pancreatic cancer, inhibition of mutant KRAS in colorectal cancer, and public health and the Inflation Reduction Act; a review article on new approaches to chronic hepatitis B; a Clinical Problem-Solving on a stormy heart; and Perspective articles on the fresh assault on insurance coverage mandates, on evidence over politics, and on death by ableism.

    New England Journal of Medicine Interviews
    The Expanding Arsenal of Oral Agents to Treat Covid-19

    New England Journal of Medicine Interviews

    Play Episode Listen Later Jan 4, 2023 17:10


    Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, L.R. Baden, and S. Morrissey. Audio Interview: The Expanding Arsenal of Oral Agents to Treat Covid-19. N Engl J Med 2023;388:e7.

    New England Journal of Medicine Interviews
    NEJM Interview: Prof. Michelle Mello on Braidwood Management Inc. v. Becerra and its potential implications.

    New England Journal of Medicine Interviews

    Play Episode Listen Later Jan 4, 2023 10:57


    Prof. Michelle Mello is a professor of law and of health policy at Stanford University. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. M.M. Mello and A.J. O'Connell. The Fresh Assault on Insurance Coverage Mandates. N Engl J Med 2023;388:1-3.

    Physician's Weekly Podcast
    Anticipated Medical Innovations for 2023

    Physician's Weekly Podcast

    Play Episode Listen Later Jan 4, 2023 29:55


    As 2023 is upon us, we are probably being realistic to expect continued inflation, a choppy economy, COVID-19 disruptions in healthcare, and on-going supply chain disruptions continuing into the year. Some leaders in healthcare systems are even predicting an “exceptionally turbulent 2023.”1 While inflation appears to be stabilizing, the higher cost of consumer goods is making it difficult for some people to pay for medical services, therapies, and devices. As a result, healthcare consumers might put off buying prescriptions or medical devices that can help them treat or monitor a condition. On the flip side, but much harder to predict, there will be a number of significant medical advances, many of which will be incremental improvements, and a few of which will be major breakthroughs. PW Podcast host Rachel Giles, MD, and PW editorial board member Alex McDonald, MD, discuss the trends to watch this year, from wearables and patient engagement to next-generation therapies and vaccines.Happy New Year!References:https://www2.deloitte.com/us/en/blog/health-care-blog/2022/2023-outlook-for-health-care-could-margins-staffing-stall-progress-to-future-of-health.htmlGene therapy pipeline 1Q2022-2Q 2025, CVS Health, February 2, 2022; Approved cellular and gene therapy products, FDA, September 19, 2022; The state of the industry, Alliance for Regenerative Medicine, January 26, 2021van Dyck CH, et al. Lecanemab in Early Alzheimer's Disease. N Engl J Med. 2022 Nov 29. doi: 10.1056/NEJMoa2212948. Epub ahead of print. https://www.nature.com/articles/d41586-022-03081-0 

    New England Journal of Medicine Interviews
    NEJM Interview: Dr. Armand Sprecher on the importance of mutual understanding in outbreak control, focusing on a recent outbreak of Sudan virus disease

    New England Journal of Medicine Interviews

    Play Episode Listen Later Dec 28, 2022 6:04 Very Popular


    Dr. Armand Sprecher is a public health specialist at Médecins Sans Frontières. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. A. Sprecher. Understanding the Key to Outbreak Control — Sudan Virus Disease in Uganda. N Engl J Med 2022;387:2393-2395.

    NEJM This Week — Audio Summaries
    NEJM This Week — December 29, 2022

    NEJM This Week — Audio Summaries

    Play Episode Listen Later Dec 28, 2022 25:47 Very Popular


    Featuring articles on chlorthalidone in cardiovascular events, vaccines for Zaire Ebola virus disease, haloperidol for delirium in ICU patients, and reporting of emissions to achieve net-zero health care; a review article on alcohol-associated hepatitis; a case report of a man with exertional chest discomfort; and Perspective articles on understanding the key to outbreak control, on hospitals and health equity, and on engineering for grief.

    AUAUniversity
    Advancing Women in Urology: Sponsorship and Its Role in Career Advancement in Medicine

    AUAUniversity

    Play Episode Listen Later Dec 26, 2022 37:03


    Advancing Women in Urology: Sponsorship and It's Role in Career Advancement in Medicine Host: Jay D. Raman, MD, FACS Guest: Peggy Pearle, MD and Simone Thavaseelan, MD Outline: Segment #1 Defining Sponsorship Segment #2 Role in Career Advancement/Importance Segment #3 Identifying the Issue Segment #4 Key Characteristics of healthy/effective Sponsorship Segment #5 Opportunities for Action ACKNOWLEDGEMENT This educational series was made possible by support from Urovant Resources: Jain, S. Why Sponsorship in Medicine Matters. Wolters Kluwer Health, https://www.wolterskluwer.com/en/expert-insights/why-sponsorship-in-medicine-matters (2020). Ayyala, M.S., et al. Mentorship Is Not Enough: Exploring Sponsorship and Its Role in Career Advancement in Academic Medicine. Acad Med. 94, 94-100 (2019). Lewiss R.E., et al. Is Academic Medicine Making Mid-Career Women Physicians Invisible? J Womens Health (Larchmt). 29,187-192 (2020). Tesch, B.J., Wood, H.M., Helwig, A.L., Nattinger, A.B. Promotion of women physicians in academic medicine. Glass ceiling or sticky floor? JAMA. 273,1022-5 (1995). Silva, C. Study: Women Get Fewer Game Changing Leadership Roles. Harvard Business Review, https://hbr.org/2012/11/study-women-get-fewer-game-changing Hewlett, S.A., Peraino, K., Sherbin, L., Sumberg, K. The Sponsor Effect: Breaking Through the Last Glass Ceiling. Boston, Mass Harvard Business Review (2011). Richter, K.P., et al. Women Physicians and Promotion in Academic Medicine. N Engl J Med. 383, 2148-2157 (2020). Foust-Cummings H. Sponsoring Women to Success. Catalyst, http://www.catalyst.org/system/files/sponsoring_women_to_success.pdf. (2011) Velez, D., et al. Rising Tides: Challenges and Opportunities for Women in the Urologic Workforce. Urology. 150, 47-53 (2021). Harris, C. How to find the person who can help you get ahead at work. TEDWomen, https://www.youtube.com/watch?v=gpE_W50OTUc.(2018). Penaloza NG,, et al. Someone Like Me: An Examination of the Importance of Race-Concordant Mentorship in Urology. Urology. 22. (2022) Butler, P.D. When excellence is still not enough. Am J Surg. 220, 543-544 (2020)

    Evidence Based Hair
    Season Finale (PART 1 of 2): Top 20 Hair Research Studies of 2022

    Evidence Based Hair

    Play Episode Listen Later Dec 23, 2022 77:33


    The season finale summarizes the top 20 studies of the 2022 calendar year. This episode addresses studies in androgenetic alopecia and alopecia areata (studies 1 to 11). Studies 12 to 20 are found in Part 2 (season 3 episode 10)   STUDIES IN FEMALE PATTERN HAIR LOSS AND MALE PATTERN HAIR LOSS STUDY 1: Qui Y et al. Systematic Review and Meta-analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia. Acta Derm Venereol. 2022 Feb 8;102:adv00645 STUDY 2: Cao L et al. Nailfold capillaroscopy alterations in androgenetic alopecia: A cross-sectional study. Indian J Dermatol Venereol Leprol. 2022 Feb 28;1-7. doi: 10.25259/IJDVL_714_2021. STUDY 3: Sanabria et al. Prospective cardiovascular evaluation with 24-h Holter and 24-h ambulatory blood pressure monitoring in men using 5 mg oral minoxidil for androgenetic alopecia. J Am Acad Dermatol. 2022 May 18;   STUDY 4: Jimenez-Cauhe J et al. Before-after study with 24-hour ambulatory blood pressure monitoring after the first dose of 5 mg oral minoxidil. J Am Acad Dermatol. 2022 Dec;87(6):e235-e237.   STUDY 5: Gupta AK et al. Relative Efficacy of Minoxidil and the 5-alpha Reductase Inhibitors in Androgenetic Alopecia Treatment of Male Patients: A Network Meta-analysis. JAMA Dermatol. 2022 Feb 2:e215743.   STUDY 6: Gupta AK and Bamimore M. Platelet-Rich Plasma Monotherapies for Androgenetic Alopecia: A Network Meta-Analysis and Meta-Regression Study. J Drugs Dermatol. 2022 Sep 1;21(9):943-952.   STUDY 7: Gupta AK et al. There Is a Positive Dose-Dependent Association between Low-Dose Oral Minoxidil and Its Efficacy for Androgenetic Alopecia: Findings from a Systematic Review with Meta-Regression Analyses. Skin Appendage Disord. 2022 Sep; 8(5): 355–36   STUDY 8: Klein E et al. Comparing combination low-dose oral minoxidil and topical minoxidil with oral minoxidil alone for the treatment of non-scarring alopecia; a retrospective chart review. J Cosmet Dermatol. 2022 Jun 1.   STUDY 9: Liang  X et al. Efficacy and Safety of 5% Minoxidil Alone, Minoxidil Plus Oral Spironolactone, and Minoxidil Plus Microneedling on Female Pattern Hair Loss: A Prospective, Single-Center, Parallel-Group, Evaluator Blinded, Randomized Trial. Front Med (Lausanne). 2022 Jul 11;9:905140.   STUDIES IN ALOPECIA AREATA     STUDY 10: King B et al. Two Phase 3 Trials of Baricitinib for                  Alopecia Areata. N Engl J Med. 2022 Mar 26.   STUDY 11: Anna Waśkiel-Burnat et al. Patients with alopecia areata are at risk of endothelial dysfunction: results of a case-control study. Clin Exp Dermatol. 2022 Mar 31.     STUDIES IN HAIR SHEDDING/TELOGEN EFFLUVIUM/ COVID19   STUDY 12: Muller-Ramos P et al. Post-COVID-19 hair loss: prevalence and associated factors among 5,891 patients. Int J Dermatol 2022 Jan 26.   STUDY 13: Anna Carolina Miola et al. Early-onset effluvium secondary to COVID-19: Clinical and histologic characterization. J Am Acad Dermatol. 2022   STUDY 14: Mazeto IFS et al. Ultrastructural evidence for anagen hair follicle infection with SARS-CoV-2 in early-onset COVID-19 effluvium. J Eur Acad Dermatol Venereol. 2022 Jun 20.     STUDIES IN SCARRING ALOPECIA   STUDY 15: Dubin C et al. Scalp and serum profiling of frontal fibrosing alopecia reveals scalp immune and fibrosis dysregulation with no systemic involvement. J Am Acad Dermatol. 2022 Mar;86(3):551-562. doi: 10.1016/j.jaad.2021.05.016   STUDY 16: Jamerson et al. Gene expression profiling suggests severe, extensive central centrifugal cicatricial alopecia may be both clinically and biologically distinct from limited disease subtypes Exp Dermatol. 2022 Jan   STUDY 17: Joshi TP et al. Prevalence of lichen planopilaris in the United States: A cross-sectional study of the All of Us research program. JAAD Int. 2022 Jun 13;8:69-70.   STUDY 18: Joshi et al. Comorbidities associated with lichen planopilaris: a case-control study using the All of Us database. Int J Dermatol. 2022 Oct 2.     STUDIES  IN VARIOUS TOPICS   STUDY 19: Chang CJ et al. Use of Straighteners and Other Hair Products and Incident Uterine Cancer. J Natl Cancer Inst. 2022 Oct 17;djac165.   STUDY 20: Ying-Yi Lu et al. Impact of seborrheic dermatitis on osteoporosis risk: A population-based cohort study. J Dermatol. 2022 Sep 12.

    Evidence Based Hair
    Season Finale (PART 2 of 2): Top 20 Hair Research Studies of 2022

    Evidence Based Hair

    Play Episode Listen Later Dec 23, 2022 54:53


    The season finale summarizes the top 20 studies of the 2022 calendar year. This episode addresses studies in hair shedding, scarring alopecia, seborrheic dermatitis and hair straighteners (studies 12 to 20). Studies 1 to 11 are found in Part 1 (season 3 episode 9)     STUDIES IN HAIR SHEDDING/TELOGEN EFFLUVIUM/ COVID19   STUDY 12: Muller-Ramos P et al. Post-COVID-19 hair loss: prevalence and associated factors among 5,891 patients. Int J Dermatol 2022 Jan 26.   STUDY 13: Anna Carolina Miola et al. Early-onset effluvium secondary to COVID-19: Clinical and histologic characterization. J Am Acad Dermatol. 2022   STUDY 14: Mazeto IFS et al. Ultrastructural evidence for anagen hair follicle infection with SARS-CoV-2 in early-onset COVID-19 effluvium. J Eur Acad Dermatol Venereol. 2022 Jun 20.     STUDIES IN SCARRING ALOPECIA   STUDY 15: Dubin C et al. Scalp and serum profiling of frontal fibrosing alopecia reveals scalp immune and fibrosis dysregulation with no systemic involvement. J Am Acad Dermatol. 2022 Mar;86(3):551-562. doi: 10.1016/j.jaad.2021.05.016   STUDY 16: Jamerson et al. Gene expression profiling suggests severe, extensive central centrifugal cicatricial alopecia may be both clinically and biologically distinct from limited disease subtypes Exp Dermatol. 2022 Jan   STUDY 17: Joshi TP et al. Prevalence of lichen planopilaris in the United States: A cross-sectional study of the All of Us research program. JAAD Int. 2022 Jun 13;8:69-70.   STUDY 18: Joshi et al. Comorbidities associated with lichen planopilaris: a case-control study using the All of Us database. Int J Dermatol. 2022 Oct 2.     STUDIES  IN VARIOUS TOPICS   STUDY 19: Chang CJ et al. Use of Straighteners and Other Hair Products and Incident Uterine Cancer. J Natl Cancer Inst. 2022 Oct 17;djac165.   STUDY 20: Ying-Yi Lu et al. Impact of seborrheic dermatitis on osteoporosis risk: A population-based cohort study. J Dermatol. 2022 Sep 12.     STUDIES IN PART 1 of PODCAST  STUDIES IN AGA STUDY 1: Qui Y et al. Systematic Review and Meta-analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia. Acta Derm Venereol. 2022 Feb 8;102:adv00645 STUDY 2: Cao L et al. Nailfold capillaroscopy alterations in androgenetic alopecia: A cross-sectional study. Indian J Dermatol Venereol Leprol. 2022 Feb 28;1-7. doi: 10.25259/IJDVL_714_2021. STUDY 3: Sanabria et al. Prospective cardiovascular evaluation with 24-h Holter and 24-h ambulatory blood pressure monitoring in men using 5 mg oral minoxidil for androgenetic alopecia. J Am Acad Dermatol. 2022 May 18;   STUDY 4: Jimenez-Cauhe J et al. Before-after study with 24-hour ambulatory blood pressure monitoring after the first dose of 5 mg oral minoxidil. J Am Acad Dermatol. 2022 Dec;87(6):e235-e237.   STUDY 5: Gupta AK et al. Relative Efficacy of Minoxidil and the 5-alpha Reductase Inhibitors in Androgenetic Alopecia Treatment of Male Patients: A Network Meta-analysis. JAMA Dermatol. 2022 Feb 2:e215743.   STUDY 6: Gupta AK and Bamimore M. Platelet-Rich Plasma Monotherapies for Androgenetic Alopecia: A Network Meta-Analysis and Meta-Regression Study. J Drugs Dermatol. 2022 Sep 1;21(9):943-952.   STUDY 7: Gupta AK et al. There Is a Positive Dose-Dependent Association between Low-Dose Oral Minoxidil and Its Efficacy for Androgenetic Alopecia: Findings from a Systematic Review with Meta-Regression Analyses. Skin Appendage Disord. 2022 Sep; 8(5): 355–36   STUDY 8: Klein E et al. Comparing combination low-dose oral minoxidil and topical minoxidil with oral minoxidil alone for the treatment of non-scarring alopecia; a retrospective chart review. J Cosmet Dermatol. 2022 Jun 1.   STUDY 9: Liang  X et al. Efficacy and Safety of 5% Minoxidil Alone, Minoxidil Plus Oral Spironolactone, and Minoxidil Plus Microneedling on Female Pattern Hair Loss: A Prospective, Single-Center, Parallel-Group, Evaluator Blinded, Randomized Trial. Front Med (Lausanne). 2022 Jul 11;9:905140.   STUDIES IN ALOPECIA AREATA     STUDY 10: King B et al. Two Phase 3 Trials of Baricitinib for                  Alopecia Areata. N Engl J Med. 2022 Mar 26.   STUDY 11: Anna Waśkiel-Burnat et al. Patients with alopecia areata are at risk of endothelial dysfunction: results of a case-control study. Clin Exp Dermatol. 2022 Mar 31.  

    New England Journal of Medicine Interviews
    NEJM Interview: Prof. Sabrina Corlette on the history of the U.S. health insurance system and persistent coverage and affordability challenges.

    New England Journal of Medicine Interviews

    Play Episode Listen Later Dec 21, 2022 9:34


    Prof. Sabrina Corlette is a research professor and codirector of the Center on Health Insurance Reforms at the Georgetown University McCourt School of Public Policy. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. S. Corlette and C.H. Monahan. U.S. Health Insurance Coverage and Financing. N Engl J Med 2022;387:2297-2300.

    New England Journal of Medicine Interviews

    NEJM AI Grand Rounds, hosted by Arjun (Raj) Manrai, Ph.D. and Andrew Beam, Ph.D., features informal conversations with a variety of unique experts exploring the deep issues at the intersection of artificial intelligence, machine learning, and medicine. You'll learn how AI will change clinical practice and healthcare, how it will impact the patient experience, and about the people who are pushing for innovation. Whether you are an AI researcher or a practicing clinician, these conversations will enlighten and surprise you as we journey through this very exciting field. Produced by NEJM Group.

    New England Journal of Medicine Interviews
    Potential Covid Vaccine Strategies

    New England Journal of Medicine Interviews

    Play Episode Listen Later Dec 21, 2022 21:50


    Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, L.R. Baden, and S. Morrissey. Audio Interview: Potential Covid Vaccine Strategies. N Engl J Med 2022;387:e75.

    HelixTalk - Rosalind Franklin University's College of Pharmacy Podcast
    158 - PADing Your Understanding of Peripheral Arterial Disease: A Brief Treatment Overview

    HelixTalk - Rosalind Franklin University's College of Pharmacy Podcast

    Play Episode Listen Later Dec 21, 2022 49:23


    In this episode, we will discuss all things peripheral arterial disease – definitions, staging, clinical presentation, risk factors, goals of therapy, and guideline-directed medication therapy recommendations including the newest evidence for the use of DOACs. Key Concepts Addressing modifiable risk factors (weight loss, smoking cessation, blood pressure and blood glucose control, dyslipidemia, structured exercise program, etc.) are recommended for the treatment of PAD. Single antiplatelet therapy with either aspirin 81 mg or clopidogrel 75 mg daily are recommended in patients to reduce stroke, MI and other vascular deaths in symptomatic (1A) and asymptomatic patients (IIa- C-EO). Rivaroxaban 2.5 mg BID, when added to aspirin 81 mg daily, is superior to aspirin alone in preventing composite outcome of stroke, MI, and CV death in PAD patients with recent revascularization surgery for PAD but increases the risk of major bleeding. In the absence of heart failure, cilostazol is effective in improving symptoms, quality of life, and increasing walking distance in patients with intermittent claudication.  References Gerhard-Herman MD, Gornik HL, Barrett C, et al. 2016 AHA/ACC Guideline on the Management of Patients With Lower Extremity Peripheral Artery Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2017;135:e686–e725. https://doi.org/10.1161/CIR.0000000000000470 Criqui MH, Matsushita K, Aboyans V, et al. Lower Extremity Peripheral Artery Disease: Contemporary Epidemiology, Management Gaps, and Future Directions: A Scientific Statement From the American Heart Association. Circulation. 2021;144:e171–e191. https://doi.org/10.1161/CIR.0000000000001005 Alonso-Coello P, Bellmunt S, McGorrian C, Anand SS, Guzman R, Criqui MH, Akl EA, Vandvik PO, Lansberg MG, Guyatt GH, Spencer FA. Antithrombotic therapy in peripheral artery disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012 Feb;141(2 Suppl):e669S-e690S. doi: 10.1378/chest.11-2307. PMID: 22315275; PMCID: PMC3278062. Eikelboom JW, Connolly SJ, Bosch J, et al. Rivaroxaban with or without aspirin in stable cardiovascular disease. N Engl J Med. 2017; 377:1319-1330. https://www.nejm.org/doi/full/10.1056/nejmoa1709118 Bonaca MP, Bauersachs RM, Anand SS, et al. Rivaroxaban in peripheral arterial disease after revascularization. N Engl J Med. 2020; 382:1994-2004. https://www.nejm.org/doi/full/10.1056/nejmoa2000052

    NEJM This Week — Audio Summaries
    NEJM This Week — December 22, 2022

    NEJM This Week — Audio Summaries

    Play Episode Listen Later Dec 21, 2022 31:29


    Featuring articles on surgery or endovascular therapy for limb ischemia, dupilumab in patients with eosinophilic esophagitis, an oral regimen for rifampin-resistant tuberculosis, gene therapy for ART-SCID, and recombinant ADAMTS13 in a pregnant woman with thrombotic thrombocytopenic purpura; a review article on oxygen delivery in the treatment of anemia; a case report of a woman with postpartum abdominal pain and fever; and Perspective articles on U.S. health insurance coverage and financing, on cholera in Haiti, again, and on revaluing primary care.

    Rheuminations
    Making Sense of Sensory Ganglionopathies and Sjogren's Syndrome

    Rheuminations

    Play Episode Listen Later Dec 15, 2022 37:36


    A sensational (or lack thereof) series on the signs and symptoms of the spellbinding sensory ganglionopathies. Intro :12 Today's episode :16 Anatomy review 1:32 Large fiber vs. small fiber nerves 4:47 Case presentation 6:11 Neurologic examination of patient 8:31 What is pseudoathetoid posturing? 10:11 What does it mean to be length independent? 14:30 What is sensory ganglionopathy? 16:19 How did the differential evolve throughout history? 18:50 How do things get out of the synovium? 23:19 Why does rheumatology get involved? 26:12 Case series of patients with Sjogren's syndrome and sensory ganglionopathy 28:20 How do we treat it? 32:48 Summary 34:09 Thank you 36:59 Disclosures: Brown reports no relevant financial disclosures. We'd love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum References: Amato AA, et al. N Engl J Med. 2020;doi:10.1056/NEJMra2023935. Denny-Brown D. J Neurol Neurosurg Psychiatry. 1948;doi:10.1136/jnnp.11.2.73. Griffin JW, et al. Ann Neurol. 1990;doi:10.1002/ana.410270313. Malinow K, et al. Ann Neurol. 1986;doi:10.1002/ana.410200416.

    NEJM This Week — Audio Summaries
    NEJM This Week — December 15, 2022

    NEJM This Week — Audio Summaries

    Play Episode Listen Later Dec 14, 2022 36:01 Very Popular


    Featuring articles on gene therapy for dystrophic epidermolysis bullosa, glofitamab in refractory diffuse large B-cell lymphoma, talquetamab for multiple myeloma, once-weekly semaglutide in adolescents with obesity, and on click chemistry; a review article on the risks of infection in xenotransplantation; a case report of a woman with fatigue and weight gain; and Perspective articles on a step toward interoperability of health IT, on a Covid-19 milestone attained, and on the Josephine way.

    New England Journal of Medicine Interviews
    NEJM Interview: Dr. David Blumenthal on a new federal rule that requires health care providers and other entities to share patient information.

    New England Journal of Medicine Interviews

    Play Episode Listen Later Dec 14, 2022 16:46


    Dr. David Blumenthal is the president of the Commonwealth Fund and a member of the Journal's Editorial Board. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. D. Blumenthal. A Step toward Interoperability of Health IT. N Engl J Med 2022;387:2201-2203.

    New England Journal of Medicine Interviews
    Applying New Studies of Mpox and Ebola to Covid-19

    New England Journal of Medicine Interviews

    Play Episode Listen Later Dec 14, 2022 21:11


    Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, L.R. Baden, and S. Morrissey. Audio Interview: Applying New Studies of Mpox and Ebola to Covid-19. N Engl J Med 2022;387:e74.

    NEJM This Week — Audio Summaries
    NEJM AI Grand Rounds

    NEJM This Week — Audio Summaries

    Play Episode Listen Later Dec 14, 2022 1:42


    NEJM AI Grand Rounds, hosted by Arjun (Raj) Manrai, Ph.D. and Andrew Beam, Ph.D., features informal conversations with a variety of unique experts exploring the deep issues at the intersection of artificial intelligence, machine learning, and medicine. You'll learn how AI will change clinical practice and healthcare, how it will impact the patient experience, and about the people who are pushing for innovation. Whether you are an AI researcher or a practicing clinician, these conversations will enlighten and surprise you as we journey through this very exciting field. Produced by NEJM Group.

    The EMS Lighthouse Project
    EMS LHP EP67 - DOSED-VF

    The EMS Lighthouse Project

    Play Episode Listen Later Dec 11, 2022 34:44


    If one is good, two must be better, right? If it applies to cookies and ice cream, why not defibrillators? That's the question the DOSED-VF trial set out to answer. We've covered this topic in episodes 12 and 27, including going over the pilot trial of DOSED-VF. But now the full meal deal is available. And you may have heard it was stopped early because… well, you'd best listen to find out. And, as a special bonus, Dr. Jarvis explains the difference between odds and risk after he fell off into the statistical rabbit hole. Remember, this podcast also has a YouTube version complete with graphs and charts (oh, my!): https://www.youtube.com/@FlightbridgeedHEMS/playlists Citation: 1. Cheskes S, Verbeek PR, Drennan IR, et al. Defibrillation Strategies for Refractory Ventricular Fibrillation. N Engl J Med. 2022;387(21):1947-1956. doi:10.1056/NEJMoa2207304 Other papers discussed in this episode: 2. Mapp JG, Hans AJ, Darrington AM, et al. Prehospital Double Sequential Defibrillation: A Matched Case–Control Study. Braithwaite SA, ed. Academic Emergency Medicine. 2019;26(9):994-1001. doi:10.1111/acem.13672 3. Beck LR, Ostermayer DG, Ponce JN, Srinivasan S, Wang HE. Effectiveness of Prehospital Dual Sequential Defibrillation for Refractory Ventricular Fibrillation and Ventricular Tachycardia Cardiac Arrest. Prehosp Emerg Care. 2019;23(5):597-602. doi:10.1080/10903127.2019.1584256 4.Cabanas JG, Myers JB, Williams JG, De Maio VJ, Bachman MW. Double Sequential External Defibrillation in Out-of-Hospital Refractory Ventricular Fibrillation: A Report of Ten Cases. Prehosp Emerg Care. 2015;19(1):126-130. doi:10.3109/10903127.2014.942476 5. Cheskes S, Dorian P, Feldman M, et al. Double sequential external defibrillation for refractory ventricular fibrillation: The DOSE VF pilot randomized controlled trial. Resuscitation. 2020;150:178-184. doi:10.1016/j.resuscitation.2020.02.010 6. Ranganathan P, Aggarwal R, Pramesh C. Common pitfalls in statistical analysis: Odds versus risk. Perspect Clin Res. 2015;6(4):222. doi:10.4103/2229-3485.167092See omnystudio.com/listener for privacy information.

    Behind The Knife: The Surgery Podcast
    Journal Review in Trauma Surgery: Gun Violence

    Behind The Knife: The Surgery Podcast

    Play Episode Listen Later Dec 8, 2022 22:35


    Join our Miami Trauma team including Drs. Urréchaga, Neeman, and Rattan as they dive into the literature regarding a topic that has become all too common to the US news cycle- gun violence. They will go over a recent paper from JAMA and include other important literature while trying to understand this complex problem that has been grappling US public policy.  Quick Hits: 1.     Firearm injury is the leading cause death in the US among ages 1-19 2.     For every person killed violently by someone else with a firearm, there are 3 survivors.  3.     Gun ownership triples the risk of homicide 4.     Permit laws and preventing people convicted of a violent crime from owning a firearm decrease firearm-related death and have a positive ripple effect even outside state borders. In short, for effective reductions of firearm-related injury and death, federal legislation will be more effective than state-by-state References 1.     Liu, Y, Siegel, M, Sen, B. Association of State-Level Firearm-Related Deaths With Firearm Laws in Neighboring States. JAMA Network Open. 2022;5(11):e2240750. doi:10.1001/jamanetworkopen.2022.40750 2.     Goldstick, JE, Cunningham, RM, Carter, PM. Current Causes of Death in Children and Adolescents in the United States. N Engl J Med. 2022 May 19;386(20):1955-1956. doi: 10.1056/NEJMc2201761.  3.     Kellermann, AL, Rivara, FP, Rushforth, NB, Banton, JG, Reay, DT, Francisco, JT, Locci, AB, Prodzinski, J, Hackman, BB, Somes, G. Gun Ownership as a Risk Factor for Homicide in the Home. N Engl J Med 1993; 329:1084-1091. DOI: 10.1056/NEJM199310073291506 4.     Liu Y, Siegel, M, Sen, B. Neighbors do matter: between-state firearm laws and state firearm-related deaths in the US, 2000-2017. Am J Prev Med. 2020;59(5):648-657. doi:10.1016/j.amepre.2020.06.022 5.     Siegel, M, Pahn, M, Xuan, Z, et al. Firearm-related laws in all 50 US states,1991-2016. Am J Public Health.2017; 107(7):1122-1129. doi:10.2105/AJPH.2017.303701 6.     Kalesan, B, Mobily, ME, Keiser, O, Fagan, J, Galea, S. Firearm legislation and firearm mortality in the USA: a cross-sectional, state-level study. Lancet. 2016 Apr 30;387(10030):1847-55. doi: 10.1016/S0140-6736(15)01026-0. Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.   If you liked this episode, check out other Journal Review episodes here: https://behindtheknife.org/podcast-series/journal-review/

    NEJM This Week — Audio Summaries
    NEJM This Week — December 8, 2022

    NEJM This Week — Audio Summaries

    Play Episode Listen Later Dec 7, 2022 27:49


    Featuring articles on therapy with tumor-infiltrating lymphocytes or ipilimumab in melanoma, biopsy method and overdiagnosis in prostate cancer, methylprednisolone for heart surgery in infants, and in utero enzyme-replacement therapy; a review article on hemochromatosis; a case report of a man with fatigue, weight loss, and pulmonary nodules; and Perspective articles on for-profit medical schools, on closing the gap in cancer genomic testing, and on deciding on her dimples.

    New England Journal of Medicine Interviews
    Covid-19 and Health Equity

    New England Journal of Medicine Interviews

    Play Episode Listen Later Dec 7, 2022 43:38


    Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Matifadza Hlatshwayo Davis is Director of the Department of Health of the City of St. Louis. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin and Others. Audio Interview: Covid-19 and Health Equity. N Engl J Med 2022;387:e73.

    New England Journal of Medicine Interviews
    NEJM Interview: Robert Shireman on policy changes allowing accreditation of for-profit medical schools in the United States

    New England Journal of Medicine Interviews

    Play Episode Listen Later Dec 7, 2022 8:16


    Robert Shireman is the director of higher education excellence and a senior fellow at The Century Foundation Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. R. Shireman. For-Profit Medical Schools — Concerns about Quality and Oversight. N Engl J Med 2022;387:2105-2107.

    FOAMcast -  Emergency Medicine Core Content
    Refractory Ventricular Fibrillation & Double Sequential Defibrillation

    FOAMcast - Emergency Medicine Core Content

    Play Episode Listen Later Dec 3, 2022 27:06


    In this episode, we review the largest trial of double sequential external defibrillation (DSED) and vector change (VC) defibrillation for refractory ventricular fibrillation (VFib): Cheskes S, Verbeek PR, Drennan IR, et al. Defibrillation Strategies for Refractory Ventricular Fibrillation. N Engl J Med. 2022;387(21):1947-1956. Show notes, references, & infographics: FOAMcast.org Thanks for listening! Jeremy Faust & Lauren Westafer

    New England Journal of Medicine Interviews
    NEJM Interview: Dr. Anthony Fauci on the evolution of the field of infectious diseases during his tenure at the National Institute of Allergy and Infectious Diseases.

    New England Journal of Medicine Interviews

    Play Episode Listen Later Nov 30, 2022 15:18


    Dr. Anthony Fauci is the director of the National Institute of Allergy and Infectious Diseases and chief medical advisor to President Joe Biden. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. A.S. Fauci. It Ain't Over Till It's Over … but It's Never Over — Emerging and Reemerging Infectious Diseases. N Engl J Med 2022;387:2009-2011.