Podcasts about alysson muotri

Professor Alysson R. Muotri (geneticist and developmental biologist at UC San Diego) joins for a far out conversation about sending brain organoids to the International Space Station and what they're teaching us about aging, neurological disease, and a new kind of AI. One month in orbit ages an organoid the equivalent of 10 years on Earth, and Alysson's lab has already used that compressed timeline to unlock an FDA-approved clinical trial for a drug developed in space.In this episode, we discuss:Why space accelerates brain agingThe surprising role of "junk DNA" and endogenous retroviruses in neuroinflammation and neurodegenerationWhy HIV antiretroviral drugs may be the key to treating neurological conditions What the decommissioning of the ISS and the rise of commercial space stations mean for biomedical researchHow brain organoids learn, remember, and inspire a new generation of AI algorithms beyond transformersThe bioethics frontier: when do organoids become conscious and how would we even know?Credits:Created by Greg Kubin and Matias SerebrinskyHost: Matias and GregProduced by Nico V. Rey Find us at businesstrip.fm and psymed.venturesFollow us on Instagram and Twitter!Theme music by Dorian LoveAdditional Music: Distant Daze by Zack Frank

Brain aging and neurological disease are hard to study because living human brain tissue is difficult to access. Alysson Muotri, Ph.D., UC San Diego, explains how brain organoids sent to space can model accelerated aging, reveal changes in neural networks, and help test potential treatments for brain disorders. Muotri examines space-induced senescence, fragmented network activity linked to dementia and Alzheimer's patterns, and Rett syndrome findings showing inflammation tied to endogenous retroviruses and response to antiretroviral drugs in preclinical models. He also explores using brain organoids in space to screen neuroprotective compounds, including candidates identified from Amazon plants. This work helps explain how space biology can speed research on autism, Rett syndrome, Alzheimer's disease, and other neurological conditions, and points toward new ways to test therapies on Earth. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 41475]

Brain aging and neurological disease are hard to study because living human brain tissue is difficult to access. Alysson Muotri, Ph.D., UC San Diego, explains how brain organoids sent to space can model accelerated aging, reveal changes in neural networks, and help test potential treatments for brain disorders. Muotri examines space-induced senescence, fragmented network activity linked to dementia and Alzheimer's patterns, and Rett syndrome findings showing inflammation tied to endogenous retroviruses and response to antiretroviral drugs in preclinical models. He also explores using brain organoids in space to screen neuroprotective compounds, including candidates identified from Amazon plants. This work helps explain how space biology can speed research on autism, Rett syndrome, Alzheimer's disease, and other neurological conditions, and points toward new ways to test therapies on Earth. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 41475]

Brain aging and neurological disease are hard to study because living human brain tissue is difficult to access. Alysson Muotri, Ph.D., UC San Diego, explains how brain organoids sent to space can model accelerated aging, reveal changes in neural networks, and help test potential treatments for brain disorders. Muotri examines space-induced senescence, fragmented network activity linked to dementia and Alzheimer's patterns, and Rett syndrome findings showing inflammation tied to endogenous retroviruses and response to antiretroviral drugs in preclinical models. He also explores using brain organoids in space to screen neuroprotective compounds, including candidates identified from Amazon plants. This work helps explain how space biology can speed research on autism, Rett syndrome, Alzheimer's disease, and other neurological conditions, and points toward new ways to test therapies on Earth. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 41475]

Brain aging and neurological disease are hard to study because living human brain tissue is difficult to access. Alysson Muotri, Ph.D., UC San Diego, explains how brain organoids sent to space can model accelerated aging, reveal changes in neural networks, and help test potential treatments for brain disorders. Muotri examines space-induced senescence, fragmented network activity linked to dementia and Alzheimer's patterns, and Rett syndrome findings showing inflammation tied to endogenous retroviruses and response to antiretroviral drugs in preclinical models. He also explores using brain organoids in space to screen neuroprotective compounds, including candidates identified from Amazon plants. This work helps explain how space biology can speed research on autism, Rett syndrome, Alzheimer's disease, and other neurological conditions, and points toward new ways to test therapies on Earth. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 41475]

Brain aging and neurological disease are hard to study because living human brain tissue is difficult to access. Alysson Muotri, Ph.D., UC San Diego, explains how brain organoids sent to space can model accelerated aging, reveal changes in neural networks, and help test potential treatments for brain disorders. Muotri examines space-induced senescence, fragmented network activity linked to dementia and Alzheimer's patterns, and Rett syndrome findings showing inflammation tied to endogenous retroviruses and response to antiretroviral drugs in preclinical models. He also explores using brain organoids in space to screen neuroprotective compounds, including candidates identified from Amazon plants. This work helps explain how space biology can speed research on autism, Rett syndrome, Alzheimer's disease, and other neurological conditions, and points toward new ways to test therapies on Earth. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 41475]

Brain aging and neurological disease are hard to study because living human brain tissue is difficult to access. Alysson Muotri, Ph.D., UC San Diego, explains how brain organoids sent to space can model accelerated aging, reveal changes in neural networks, and help test potential treatments for brain disorders. Muotri examines space-induced senescence, fragmented network activity linked to dementia and Alzheimer's patterns, and Rett syndrome findings showing inflammation tied to endogenous retroviruses and response to antiretroviral drugs in preclinical models. He also explores using brain organoids in space to screen neuroprotective compounds, including candidates identified from Amazon plants. This work helps explain how space biology can speed research on autism, Rett syndrome, Alzheimer's disease, and other neurological conditions, and points toward new ways to test therapies on Earth. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 41475]

Humans live in a world of ideas—born in the brain, shared through language, accumulated in culture across generations, and made reality. Professor Alysson Muotri, UC San Diego Departments of Pediatrics and Cellular and Molecular Medicine, examines how human brain evolution reflects the interplay between genetic innovation and environmental pressures, focusing on Neuro-oncological ventral antigen 1 (NOVA1), an evolutionarily conserved splicing regulator essential for neural development with a protein-coding substitution unique to modern humans compared with Neanderthals and Denisovans. By reintroducing the archaic NOVA1 allele into human induced pluripotent stem cells and studying cortical organoids, the work finds accelerated maturation, increased surface complexity, altered synaptic marker expression, and changes in electrophysiological properties. Muotri also analyzes long-term lead exposure using fossilized teeth from multiple hominid species spanning over two million years, revealing pervasive exposure across extinct and extant hominids. Lead exposure selectively disrupted FOXP2 expression in cortical and thalamic organoids carrying the archaic NOVA1 variant, and findings were independently validated in NOVA1 humanized mouse models with altered vocalization. Together, these results suggest gene–environment interactions may have influenced neural circuit development, social behavior, and complex language capacity. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41297]

Humans live in a world of ideas—born in the brain, shared through language, accumulated in culture across generations, and made reality. Professor Alysson Muotri, UC San Diego Departments of Pediatrics and Cellular and Molecular Medicine, examines how human brain evolution reflects the interplay between genetic innovation and environmental pressures, focusing on Neuro-oncological ventral antigen 1 (NOVA1), an evolutionarily conserved splicing regulator essential for neural development with a protein-coding substitution unique to modern humans compared with Neanderthals and Denisovans. By reintroducing the archaic NOVA1 allele into human induced pluripotent stem cells and studying cortical organoids, the work finds accelerated maturation, increased surface complexity, altered synaptic marker expression, and changes in electrophysiological properties. Muotri also analyzes long-term lead exposure using fossilized teeth from multiple hominid species spanning over two million years, revealing pervasive exposure across extinct and extant hominids. Lead exposure selectively disrupted FOXP2 expression in cortical and thalamic organoids carrying the archaic NOVA1 variant, and findings were independently validated in NOVA1 humanized mouse models with altered vocalization. Together, these results suggest gene–environment interactions may have influenced neural circuit development, social behavior, and complex language capacity. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41297]

Humans live in a world of ideas—born in the brain, shared through language, accumulated in culture across generations, and made reality. Professor Alysson Muotri, UC San Diego Departments of Pediatrics and Cellular and Molecular Medicine, examines how human brain evolution reflects the interplay between genetic innovation and environmental pressures, focusing on Neuro-oncological ventral antigen 1 (NOVA1), an evolutionarily conserved splicing regulator essential for neural development with a protein-coding substitution unique to modern humans compared with Neanderthals and Denisovans. By reintroducing the archaic NOVA1 allele into human induced pluripotent stem cells and studying cortical organoids, the work finds accelerated maturation, increased surface complexity, altered synaptic marker expression, and changes in electrophysiological properties. Muotri also analyzes long-term lead exposure using fossilized teeth from multiple hominid species spanning over two million years, revealing pervasive exposure across extinct and extant hominids. Lead exposure selectively disrupted FOXP2 expression in cortical and thalamic organoids carrying the archaic NOVA1 variant, and findings were independently validated in NOVA1 humanized mouse models with altered vocalization. Together, these results suggest gene–environment interactions may have influenced neural circuit development, social behavior, and complex language capacity. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41297]

Humans live in a world of ideas—born in the brain, shared through language, accumulated in culture across generations, and made reality. Professor Alysson Muotri, UC San Diego Departments of Pediatrics and Cellular and Molecular Medicine, examines how human brain evolution reflects the interplay between genetic innovation and environmental pressures, focusing on Neuro-oncological ventral antigen 1 (NOVA1), an evolutionarily conserved splicing regulator essential for neural development with a protein-coding substitution unique to modern humans compared with Neanderthals and Denisovans. By reintroducing the archaic NOVA1 allele into human induced pluripotent stem cells and studying cortical organoids, the work finds accelerated maturation, increased surface complexity, altered synaptic marker expression, and changes in electrophysiological properties. Muotri also analyzes long-term lead exposure using fossilized teeth from multiple hominid species spanning over two million years, revealing pervasive exposure across extinct and extant hominids. Lead exposure selectively disrupted FOXP2 expression in cortical and thalamic organoids carrying the archaic NOVA1 variant, and findings were independently validated in NOVA1 humanized mouse models with altered vocalization. Together, these results suggest gene–environment interactions may have influenced neural circuit development, social behavior, and complex language capacity. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41297]

Humans live in a world of ideas—born in the brain, shared through language, accumulated in culture across generations, and made reality. Professor Alysson Muotri, UC San Diego Departments of Pediatrics and Cellular and Molecular Medicine, examines how human brain evolution reflects the interplay between genetic innovation and environmental pressures, focusing on Neuro-oncological ventral antigen 1 (NOVA1), an evolutionarily conserved splicing regulator essential for neural development with a protein-coding substitution unique to modern humans compared with Neanderthals and Denisovans. By reintroducing the archaic NOVA1 allele into human induced pluripotent stem cells and studying cortical organoids, the work finds accelerated maturation, increased surface complexity, altered synaptic marker expression, and changes in electrophysiological properties. Muotri also analyzes long-term lead exposure using fossilized teeth from multiple hominid species spanning over two million years, revealing pervasive exposure across extinct and extant hominids. Lead exposure selectively disrupted FOXP2 expression in cortical and thalamic organoids carrying the archaic NOVA1 variant, and findings were independently validated in NOVA1 humanized mouse models with altered vocalization. Together, these results suggest gene–environment interactions may have influenced neural circuit development, social behavior, and complex language capacity. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Science] [Show ID: 41297]

First up on the podcast, increased carbon dioxide emissions sink more acidity into the ocean, but checking pH all over the world, up and down the water column, is incredibly challenging. Staff Writer Paul Voosen joins host Sarah Crespi to discuss a technique that takes advantage of how sound moves through the water to detect ocean acidification. Next on the show, we visit the lab of University of California San Diego professor Alysson Muotri at the Sanford Consortium, where he grows human brain organoids—multicellular structures that function like underdeveloped brains. Muotri used organoids to compare a protein that appears to be protective in human brains against the effects of lead toxicity with the archaic version of the protein that was present in our extinct cousins, like Denisovans and Neanderthals. His work suggests lead exposure differently affected our ancestors and our archaic cousins, possibly helping us survive to the present day. Finally, stay tuned for the last in our six-part series on books exploring the science of death. This month, host Angela Saini talks with astrophysicist Katie Mack about how the universe might end and her 2021 book The End of Everything: (Astrophysically Speaking). This week's episode was produced with help from Podigy. Learn more about your ad choices. Visit megaphone.fm/adchoices

First up on the podcast, increased carbon dioxide emissions sink more acidity into the ocean, but checking pH all over the world, up and down the water column, is incredibly challenging. Staff Writer Paul Voosen joins host Sarah Crespi to discuss a technique that takes advantage of how sound moves through the water to detect ocean acidification. Next on the show, we visit the lab of University of California San Diego professor Alysson Muotri at the Sanford Consortium, where he grows human brain organoids—multicellular structures that function like underdeveloped brains. Muotri used organoids to compare a protein that appears to be protective in human brains against the effects of lead toxicity with the archaic version of the protein that was present in our extinct cousins, like Denisovans and Neanderthals. His work suggests lead exposure differently affected our ancestors and our archaic cousins, possibly helping us survive to the present day. Finally, stay tuned for the last in our six-part series on books exploring the science of death. This month, host Angela Saini talks with astrophysicist Katie Mack about how the universe might end and her 2021 book The End of Everything: (Astrophysically Speaking). This week's episode was produced with help from Podigy. Learn more about your ad choices. Visit megaphone.fm/adchoices

Diretamente do Afya Summit 2025, Alysson Muotri, PhD, professor da UC San Diego, compartilha suas pesquisas sobre organoides cerebrais e seu impacto nas neurociências e na medicina. Junto com Dr. Eduardo Moura e Dr. Marcos Valadares, ele fala sobre o futuro da medicina, genética e tecnologia.Ouça agora e compartilhe com seus colegas médicos!

Mini-brains in space. Did you know that we can study something called brain organoids, effectively mini-brains, in the special conditions in space, on the International Space Station, and that such studies may help us with diseases like Alzheimers, Autism or Parkinsons? My guest this week is Prof. Alysson Muotri from the University of California San Diego. He and his team have flown such brain organoids to the ISS many times already. Don't miss this episode on what I consider one of the most exciting intersections of space and biology, and ultimately a potential source of massive positive impact right here on Earth!

In this fascinating episode of Research Renaissance, host Deborah Westphall welcomes Dr. Alysson Muotri,  a professor in the Departments of Pediatrics and Cellular & Molecular Medicine at the University of California, San Diego., for a deep dive into what makes the human brain unique—and how understanding that uniqueness might unlock new treatments for neurological disorders. From stem cell brain models grown in the lab to sending "mini-brains" into space, Dr. Muotri shares his bold, unconventional path to advancing neuroscience and personalized medicine.Dr. Muotri discusses his work creating 3D brain organoids to model human neurological development, including conditions like autism and epilepsy. He explains how modern humans evolved slower brain development than our ancestors, and how that developmental window leaves us vulnerable to mutation and disease—but also offers the complexity that makes human cognition and collaboration possible.The conversation also touches on ethical frontiers, including the potential for lab-grown brains to develop consciousness, the future of neuroscience in space, and how traditional Amazonian medicine may offer clues to protecting the brain.In This Episode:Why collaboration and sociality are key traits of the human brainHow brain organoids help us study disorders like autism without invasive methodsUsing Neanderthal DNA to uncover what's uniquely humanWhy space accelerates brain aging—and how that might fast-track drug discoveryThe ethical questions we must face as lab-grown brain tissues become more advancedHow Dr. Muotri's personal journey as a father shaped his scientific missionThe need for alternative funding models to support bold, high-risk scienceQuotes to Remember:

Building miniature brains may sound like a page out of a science fiction novel, but fact is indeed stranger than fiction. Researchers around the world grow brain organoids—3D miniature brains—to better understand brain development, aging, injury, and other disorders, as well as to test new treatment strategies. Some scientists take brain building to the next level by launching their brain organoids into outer space. In this episode, Iris Kulbatski from The Scientist spoke with Alysson Muotri, a University of California, San Diego professor and Stem Cell Program director to learn more about how microgravity affects the cellular and molecular biology of brain organoids and how these discoveries can improve human health.  The Scientist Speaks is a podcast produced by The Scientist's Creative Services Team. Our podcast is by scientists and for scientists. Once a month, we bring you the stories behind news-worthy molecular biology research. This month's episode is sponsored by ACROBiosystems and Molecular Devices.

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]

Dr. Alysson Muotri, PhD é professor na Universidade da Califórnia - San Diego, e seus estudos se concentram em entender o cérebro humano a partir de uma perspectiva evolutiva e de desenvolvimento. Dr Muotri cria "organóides cerebrais” ou MINICÉREBRO em laboratório para estudar as propriedades evolutivas que nos diferenciam dos outros primatas, como os Neandertais. Seu trabalho ajuda a entender doenças neurológicas complexas, identificar novas terapias e reduzir o tempo para levar novos medicamentos a ensaios clínicos. Ele revelará descobertas surpreendentes sobre estes estudo; Considero que o avanço científico liderado pelo Dr Muotri merece o prêmio Nobel de Medicina.Sintonize o Podbrand agora!https://podbrand.bio.link@BOrganoid@alyssonmuotrihttps://www.facebook.com/muotri/https://www.youtube.com/@alyssonmuotri7220/featuredhttps://www.linkedin.com/in/alysson-muotri-64499aa/ASSINE A REVISTA AUTISMOhttps://rebrand.ly/assinerevistaautismoRevista AutismoCanalAutismo.com.br/revistahttps://instagram.com/RevistaAutismohttps://www.linkedin.com/company/RevistaAutismoTismoo Biotechwww.tismoo.ushttps://www.instagram.com/_tismoo/ https://www.linkedin.com/company/tismoo/Tismoo me (única rede social do mundo dedicada ao autismo)Tirmoo.mehttps://www.instagram.com/tismoo.me/https://www.linkedin.com/company/tismoo-mePODBRAND, o podcast sobre DESIGN, ESTRATÉGIA e INOVAÇÃO.Nosso objetivo é que você alcance SUA MELHOR VERSÃO.NOTE: A música está sob licença de copyright.https://lnkd.in/d39mudbH#design #estratégia #inovação #branding#designexport #designestratégico #valordemarca #opodcastdodesign #gestãodevalor#mauriciomedeirosoficial #empreendedorismocriativo#gestãodeinovação #podbrand #suamelhorversão #podbrandoficial #designdeserviços #TOC #theoryofconstraints#teoriadasrestrições #construçãodevalor #fashionglobalbrand #designdaciência Hosted on Acast. See acast.com/privacy for more information.

Please support the podcast by taking our short listener survey: https://www.surveymonkey.com/r/intotheimpossible Be sure to watch the video of this episode on YouTube here: https://youtu.be/hDKGF5W4Qis?sub_confirmation=1 Where does consciousness come from? Can we cure autism? Can we grow a human BRAIN in Space? Dr. Alysson Muotri joins me to discuss all these fascinating questions and more. Brain organoids are lab-grown minibrains that mimic structural and functional features of full-size brains. They are created by culturing pluripotent stem cells in a three-dimensional rotational bioreactor, and they develop over a course of months. Brain organoids have emerged as novel model systems that can be used to investigate human brain development and disorders34, as well as evolutionary studies and neural network research Muotri is a Professor at the Departments of Pediatrics and Cellular & Molecular Medicine at UC San Diego, an Associate Director of CARTA, The Center for Research and Training in Anthropology, and Director of the Stem Cell Program, and of the Archealization Center (ArchC) at UC San Diego. He moved to the Salk Institute as Pew Latin America Fellow in 2002 for postdoctoral training in the fields of neuroscience and stem cell biology. His research focuses on brain evolution and modeling neurological diseases using human-induced pluripotent stem cells and brain organoids. He has an additional focus on solving one of life's greatest mysteries: What is it that makes us uniquely human? Our unique social brains are one of the key distinguishing factors between humans and other primates. We are even very different from our closest relatives, the Neanderthals. His work has implications for the generation of human disease models by determining the molecular and cellular mechanisms driving neurological complex disorders, such as autism. It is also creating opportunities for identifying and testing novel therapeutic approaches. Understanding the evolutionary path and the tradeoffs of the modern human brain will likely illuminate the origins of human disease. Dr. Moutri has received several awards, including the prestigious NIH Director's New Innovator Award, NARSAD, Emerald Foundation Young Investigator Award, Surugadai Award, Rock Star of Innovation, NIH EUREKA Award, and two Telly Awards for Excellence in Science Communication. Links: Department of Cellular and Molecular Medicine: cmm.ucsd.edu Center for Academic Research and Training in Anthropogeny: carta.anthropogeny.org/users/alysson-muotri the Archealization Center: Archc.ucsd.edu Subscribe to the Jordan Harbinger Show for amazing content from Apple's best podcast of 2018! https://www.jordanharbinger.com/podcasts  Please leave a rating and review: On Apple devices, click here, https://apple.co/39UaHlB On Spotify it's here: https://spoti.fi/3vpfXok On Audible it's here https://tinyurl.com/wtpvej9v  Find other ways to rate here: https://briankeating.com/podcast Support the podcast on Patreon https://www.patreon.com/drbriankeating  or become a Member on YouTube- https://www.youtube.com/channel/UCmXH_moPhfkqCk6S3b9RWuw/join To advertise with us, contact advertising@airwavemedia.com Learn more about your ad choices. Visit megaphone.fm/adchoices

How do research communities contend with controversial science? J. Benjamin Hurlbut, Ph.D., Arizona State University, Alysson Muotri, Ph.D., UC San Diego, Matthew Porteus, M.D., Ph.D., Stanford University, and Jacob (Yaqub) Hanna, M.D., Ph.D., Weizmann Institute of Science, explore controversial case studies and the limitations of scientific deliberation/dissent/ambivalence. Series: "Stem Cell Channel" [Health and Medicine] [Humanities] [Science] [Show ID: 38729]

How do research communities contend with controversial science? J. Benjamin Hurlbut, Ph.D., Arizona State University, Alysson Muotri, Ph.D., UC San Diego, Matthew Porteus, M.D., Ph.D., Stanford University, and Jacob (Yaqub) Hanna, M.D., Ph.D., Weizmann Institute of Science, explore controversial case studies and the limitations of scientific deliberation/dissent/ambivalence. Series: "Stem Cell Channel" [Health and Medicine] [Humanities] [Science] [Show ID: 38729]

How do research communities contend with controversial science? J. Benjamin Hurlbut, Ph.D., Arizona State University, Alysson Muotri, Ph.D., UC San Diego, Matthew Porteus, M.D., Ph.D., Stanford University, and Jacob (Yaqub) Hanna, M.D., Ph.D., Weizmann Institute of Science, explore controversial case studies and the limitations of scientific deliberation/dissent/ambivalence. Series: "Stem Cell Channel" [Health and Medicine] [Humanities] [Science] [Show ID: 38729]

How do research communities contend with controversial science? J. Benjamin Hurlbut, Ph.D., Arizona State University, Alysson Muotri, Ph.D., UC San Diego, Matthew Porteus, M.D., Ph.D., Stanford University, and Jacob (Yaqub) Hanna, M.D., Ph.D., Weizmann Institute of Science, explore controversial case studies and the limitations of scientific deliberation/dissent/ambivalence. Series: "Stem Cell Channel" [Health and Medicine] [Humanities] [Science] [Show ID: 38729]

How do research communities contend with controversial science? J. Benjamin Hurlbut, Ph.D., Arizona State University, Alysson Muotri, Ph.D., UC San Diego, Matthew Porteus, M.D., Ph.D., Stanford University, and Jacob (Yaqub) Hanna, M.D., Ph.D., Weizmann Institute of Science, explore controversial case studies and the limitations of scientific deliberation/dissent/ambivalence. Series: "Stem Cell Channel" [Health and Medicine] [Humanities] [Science] [Show ID: 38729]

How do research communities contend with controversial science? J. Benjamin Hurlbut, Ph.D., Arizona State University, Alysson Muotri, Ph.D., UC San Diego, Matthew Porteus, M.D., Ph.D., Stanford University, and Jacob (Yaqub) Hanna, M.D., Ph.D., Weizmann Institute of Science, explore controversial case studies and the limitations of scientific deliberation/dissent/ambivalence. Series: "Stem Cell Channel" [Health and Medicine] [Humanities] [Science] [Show ID: 38729]

How do research communities contend with controversial science? J. Benjamin Hurlbut, Ph.D., Arizona State University, Alysson Muotri, Ph.D., UC San Diego, Matthew Porteus, M.D., Ph.D., Stanford University, and Jacob (Yaqub) Hanna, M.D., Ph.D., Weizmann Institute of Science, explore controversial case studies and the limitations of scientific deliberation/dissent/ambivalence. Series: "Stem Cell Channel" [Health and Medicine] [Humanities] [Science] [Show ID: 38729]

Alysson Muotri discusses modeling Pitt-Hopkins syndrome (PTHS) using stem cells and brain organoids. He shares how rescuing TCF4 expression with CRISPR-mediated epigenetic induction of AAV vector delivery provides a gateway for targeted therapeutics for PTHS and related conditions. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38516]

Alysson Muotri discusses modeling Pitt-Hopkins syndrome (PTHS) using stem cells and brain organoids. He shares how rescuing TCF4 expression with CRISPR-mediated epigenetic induction of AAV vector delivery provides a gateway for targeted therapeutics for PTHS and related conditions. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38516]

Alysson Muotri discusses modeling Pitt-Hopkins syndrome (PTHS) using stem cells and brain organoids. He shares how rescuing TCF4 expression with CRISPR-mediated epigenetic induction of AAV vector delivery provides a gateway for targeted therapeutics for PTHS and related conditions. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38516]

Alysson Muotri discusses modeling Pitt-Hopkins syndrome (PTHS) using stem cells and brain organoids. He shares how rescuing TCF4 expression with CRISPR-mediated epigenetic induction of AAV vector delivery provides a gateway for targeted therapeutics for PTHS and related conditions. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38516]

Alysson Muotri discusses modeling Pitt-Hopkins syndrome (PTHS) using stem cells and brain organoids. He shares how rescuing TCF4 expression with CRISPR-mediated epigenetic induction of AAV vector delivery provides a gateway for targeted therapeutics for PTHS and related conditions. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38516]

Alysson Muotri discusses modeling Pitt-Hopkins syndrome (PTHS) using stem cells and brain organoids. He shares how rescuing TCF4 expression with CRISPR-mediated epigenetic induction of AAV vector delivery provides a gateway for targeted therapeutics for PTHS and related conditions. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38516]

What is gene therapy and how does it relate to autism? Alysson Muotri, Ph.D., contextualizes the autism spectrum, defines gene therapy, shares how human stem cells can contribute to research, and lays out how gene therapy could be used in the future. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 38387]

What is gene therapy and how does it relate to autism? Alysson Muotri, Ph.D., contextualizes the autism spectrum, defines gene therapy, shares how human stem cells can contribute to research, and lays out how gene therapy could be used in the future. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 38387]

What is gene therapy and how does it relate to autism? Alysson Muotri, Ph.D., contextualizes the autism spectrum, defines gene therapy, shares how human stem cells can contribute to research, and lays out how gene therapy could be used in the future. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 38387]

What is gene therapy and how does it relate to autism? Alysson Muotri, Ph.D., contextualizes the autism spectrum, defines gene therapy, shares how human stem cells can contribute to research, and lays out how gene therapy could be used in the future. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 38387]

What is gene therapy and how does it relate to autism? Alysson Muotri, Ph.D., contextualizes the autism spectrum, defines gene therapy, shares how human stem cells can contribute to research, and lays out how gene therapy could be used in the future. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 38387]

What is gene therapy and how does it relate to autism? Alysson Muotri, Ph.D., contextualizes the autism spectrum, defines gene therapy, shares how human stem cells can contribute to research, and lays out how gene therapy could be used in the future. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 38387]

Today we're talking to Alysson Muotri, Professor at University of California, San Diego; and we discuss how Alysson is growing brains in a lab, and what's on the cutting edge of modern autism and genetic research. All of this right here, right now, on the Modern CTO Podcast! 

Welcome to Science Philosophy in a Flash, a mini podcast series produced by The Scientist's Creative Services Team. In this series, we highlight researchers' unique outlooks on what it means to be a scientist. Alysson Muotri, a professor at the University of California, San Diego and director of the Stem Cell program, pushes the boundaries of neuroscience research. He builds brains for a living, then sends them on missions to outer space. Motivated by curiosity and creativity, his work is advancing scientists' understanding of brain development and aging. In this episode narrated by Niki Spahich, Iris Kulbatski from The Scientist's Creative Services Team spoke with Muotri to learn more about what being a scientist means to him. To learn more about Muotri's work, check out the upcoming ebook Next-Level Organoids, available on July 29th here.

A model of human cortical development could be used to instruct novel computational learning approaches. Alysson Muotri, Phd, Sujeeth Bharadwaj, PhD, Weiwei Yang, and Gabrial Silva, MSc, PhD, discuss the promise, the problems, and the potential when biology and artificial intelligence meet. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37556]