Podcasts about muotri

Dr. Alysson Muotri, PhD é professor na Universidade da Califórnia - San Diego, e seus estudos se concentram em entender o cérebro humano a partir de uma perspectiva evolutiva e de desenvolvimento. Dr Muotri cria "organóides cerebrais” ou MINICÉREBRO em laboratório para estudar as propriedades evolutivas que nos diferenciam dos outros primatas, como os Neandertais. Seu trabalho ajuda a entender doenças neurológicas complexas, identificar novas terapias e reduzir o tempo para levar novos medicamentos a ensaios clínicos. Ele revelará descobertas surpreendentes sobre estes estudo; Considero que o avanço científico liderado pelo Dr Muotri merece o prêmio Nobel de Medicina.Sintonize o Podbrand agora!https://podbrand.bio.link@BOrganoid@alyssonmuotrihttps://www.facebook.com/muotri/https://www.youtube.com/@alyssonmuotri7220/featuredhttps://www.linkedin.com/in/alysson-muotri-64499aa/ASSINE A REVISTA AUTISMOhttps://rebrand.ly/assinerevistaautismoRevista AutismoCanalAutismo.com.br/revistahttps://instagram.com/RevistaAutismohttps://www.linkedin.com/company/RevistaAutismoTismoo Biotechwww.tismoo.ushttps://www.instagram.com/_tismoo/ https://www.linkedin.com/company/tismoo/Tismoo me (única rede social do mundo dedicada ao autismo)Tirmoo.mehttps://www.instagram.com/tismoo.me/https://www.linkedin.com/company/tismoo-mePODBRAND, o podcast sobre DESIGN, ESTRATÉGIA e INOVAÇÃO.Nosso objetivo é que você alcance SUA MELHOR VERSÃO.NOTE: A música está sob licença de copyright.https://lnkd.in/d39mudbH#design #estratégia #inovação #branding#designexport #designestratégico #valordemarca #opodcastdodesign #gestãodevalor#mauriciomedeirosoficial #empreendedorismocriativo#gestãodeinovação #podbrand #suamelhorversão #podbrandoficial #designdeserviços #TOC #theoryofconstraints#teoriadasrestrições #construçãodevalor #fashionglobalbrand #designdaciência Hosted on Acast. See acast.com/privacy for more information.

¿Cómo encontrar la felicidad? En vivo PsicoDeporte Roxana Muotri en vivo #ContactoDirecto con Sebastián Franchini www.gdsradio.com www.cronosmdq.com --- Send in a voice message: https://anchor.fm/gds-radio/message

#autism #autismawareness #genetherapy #podcast #toctw #neuroscience A Gene Therapy Reverses Effects of Pitt-Hopkins Syndrome a form of Autism-Linked Mutation in Human Brain Organoids Dr. Alysson R. Muotri, a professor in the Departments of Pediatrics and Cellular & Molecular Medicine at the University of California, San Diego, is focusing his research on solving one of life's greatest mysteries- What is it that makes us uniquely human? Research tells us that one of the most influential characteristics of modern humans is our sophisticated brains, and all of the abilities that its complexity grants us. Our unique social brains are one of the key distinguishing factors between humans and other primates. We are even very different from our closest relatives, the Neanderthals, whose brains were limited in their ability to create technology, art, imagination and overall culture. Dr. Muotri is studying the brain from an evolutionary and developmental perspective, differentiating stem cells to recreate "brain organoids" in the controlled setting of a lab. This work has implications for the generation of human disease models by determining the molecular and cellular mechanisms driving neurological complex disorders, such as autism. It is also creating opportunities for identifying and testing novel therapeutic approaches; the nature of this work reduces the amount of time required for moving new drugs to clinical trials. Gaining a clearer understanding of human brain evolution is crucial for interpreting human genetic variants which lead to disease. Some of the evolutionary properties that make us uniquely human and allow us to live the advanced lifestyle we enjoy are also a root cause for a number of disorders. Our brain grants us far greater processing power than any other species, but a complex brain came with a cost: it increases the opportunity for neurological diseases. Thus, understanding the evolutionary path and the tradeoffs of the modern human brain will likely illuminate the origins of human disease. https://www.linkedin.com/in/alysson-muotri-64499aa https://medschool.ucsd.edu/som/pediatrics/research/labs/muotri-lab/Pages/default.aspx https://tismoo.us

Welcome to Science Philosophy in a Flash, a mini podcast series produced by The Scientist's Creative Services Team. In this series, we highlight researchers' unique outlooks on what it means to be a scientist. Alysson Muotri, a professor at the University of California, San Diego and director of the Stem Cell program, pushes the boundaries of neuroscience research. He builds brains for a living, then sends them on missions to outer space. Motivated by curiosity and creativity, his work is advancing scientists' understanding of brain development and aging. In this episode narrated by Niki Spahich, Iris Kulbatski from The Scientist's Creative Services Team spoke with Muotri to learn more about what being a scientist means to him. To learn more about Muotri's work, check out the upcoming ebook Next-Level Organoids, available on July 29th here.

In this episode... Dr Bahijja Raimi-Abraham asks the question "How does COVID19 affect the brain?" with guest Professor Alysson Renato Muotri who is a professor at the Departments of Pediatrics and Cellular & Molecular Medicine at UC San Diego. This episode is sponsored by The Black Dementia Company https://theblackdementiacompany.com/ Products also available at shop.alzheimers.org.uk Episode image credit: www.unsplash.com Subscribe, follow, comment and get in touch! Submit your questions or send your voice note questions (up to 30 seconds) here. e. info@mondaysciencepodcast.com Guest Bio: He is also the Director of the Stem Cell Program and Archealization Center. Dr. Muotri earned a BSc in Biological Sciences from the State University of Campinas in 1995 and a Ph.D. in Genetics in 2001 from University of Sao Paulo, in Brazil. He moved to the Salk Institute as Pew Latin America Fellow in 2002 for a postdoctoral training in the fields of neuroscience and stem cell biology. His research focuses on brain evolution and modeling neurological diseases using human induced pluripotent stem cells and brain organoids. He has received several awards, including the prestigious NIH Director's New Innovator Award, NARSAD, Emerald Foundation Young Investigator Award, Surugadai Award, Rock Star of Innovation, NIH EUREKA Award, Telly Awards among several others. Find out more about Professor Muotri here http://muotri.ucsd.edu --- Send in a voice message: https://anchor.fm/mondayscience/message

In this episode... Dr Bahijja Raimi-Abraham asks the question "How do scientists study the brain?" with guest Professor Alysson Renato Muotri who is a professor at the Departments of Pediatrics and Cellular & Molecular Medicine at UC San Diego. This episode is sponsored by The Black Dementia Company https://theblackdementiacompany.com/ Products also available at shop.alzheimers.org.uk Additional Information: Episode 25: Can lab grown brain cells, tissue or organs become conscious? - https://www.mondaysciencepodcast.com/listen/episode/199a8f00/episode-25-can-lab-grown-brain-cells-tissue-or-organs-become-conscious Wired Article "It's time for Alexa, Google Assistant and Siri to swear" - https://www.wired.co.uk/article/alexa-google-assistant-siri-swearing Episode image credit: www.unsplash.com Subscribe, follow, comment and get in touch! Submit your questions or send your voice note questions (up to 30 seconds) here. e. info@mondaysciencepodcast.com Guest Bio: He is also the Director of the Stem Cell Program and Archealization Center. Dr. Muotri earned a BSc in Biological Sciences from the State University of Campinas in 1995 and a Ph.D. in Genetics in 2001 from University of Sao Paulo, in Brazil. He moved to the Salk Institute as Pew Latin America Fellow in 2002 for a postdoctoral training in the fields of neuroscience and stem cell biology. His research focuses on brain evolution and modeling neurological diseases using human induced pluripotent stem cells and brain organoids. He has received several awards, including the prestigious NIH Director's New Innovator Award, NARSAD, Emerald Foundation Young Investigator Award, Surugadai Award, Rock Star of Innovation, NIH EUREKA Award, Telly Awards among several others. Find out more about Professor Muotri here http://muotri.ucsd.edu --- Send in a voice message: https://anchor.fm/mondayscience/message

Researcher Alysson Muotri is using stem cells to study everything from autism to the Zika virus. In this excerpt Muotri discusses stem cell and brain organoid research for possible applications to human diseases. Series: "Health Matters" [Health and Medicine] [Show ID: 36301]

Researcher Alysson Muotri is using stem cells to study everything from autism to the Zika virus. In this excerpt Muotri discusses stem cell and brain organoid research for possible applications to human diseases. Series: "Health Matters" [Health and Medicine] [Show ID: 36301]

Researcher Alysson Muotri is using stem cells to study everything from autism to the Zika virus. In this excerpt Muotri discusses stem cell and brain organoid research for possible applications to human diseases. Series: "Health Matters" [Health and Medicine] [Show ID: 36301]

Researcher Alysson Muotri is using stem cells to study everything from autism to the Zika virus. In this excerpt Muotri discusses stem cell and brain organoid research for possible applications to human diseases. Series: "Health Matters" [Health and Medicine] [Show ID: 36301]

Researcher Alysson Muotri is using stem cells to study everything from autism to the Zika virus. In this excerpt Muotri discusses stem cell and brain organoid research for possible applications to human diseases. Series: "Health Matters" [Health and Medicine] [Show ID: 36301]

Researcher Alysson Muotri is using stem cells to study everything from autism to the Zika virus. In this excerpt Muotri discusses stem cell and brain organoid research for possible applications to human diseases. Series: "Health Matters" [Health and Medicine] [Show ID: 36301]

Researcher Alysson Muotri is using stem cells to study everything from autism to the Zika virus. In this excerpt Muotri discusses stem cell and brain organoid research for possible applications to human diseases. Series: "Health Matters" [Health and Medicine] [Show ID: 36301]

Researcher Alysson Muotri is using stem cells to study everything from autism to the Zika virus. In this excerpt Muotri discusses stem cell and brain organoid research for possible applications to human diseases. Series: "Health Matters" [Health and Medicine] [Show ID: 36301]

Researcher Alysson Muotri is using stem cells to study everything from autism to the Zika virus. In this excerpt Muotri discusses stem cell and brain organoid research for possible applications to human diseases. Series: "Health Matters" [Health and Medicine] [Show ID: 36301]

Researcher Alysson Muotri is using stem cells to study everything from autism to the Zika virus. In this excerpt Muotri discusses stem cell and brain organoid research for possible applications to human diseases. Series: "Health Matters" [Health and Medicine] [Show ID: 36301]

Researcher Alysson Muotri is using stem cells to study everything from autism to the Zika virus. In this excerpt Muotri discusses stem cell and brain organoid research for possible applications to human diseases. Series: "Health Matters" [Health and Medicine] [Show ID: 36301]

Researcher Alysson Muotri is using stem cells to study everything from autism to the Zika virus. In this excerpt Muotri discusses stem cell and brain organoid research for possible applications to human diseases. Series: "Health Matters" [Health and Medicine] [Show ID: 36301]

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.07.28.225631v1?rss=1 Authors: Silva, G. A., Muotri, A. R., White, C. Abstract: A basic neurobiology-clinical trial paradigm motivates our use of constrained mathematical models and analysis of personalized human-derived brain organoids toward predicting clinical outcomes and safely developing new therapeutics. Physical constraints imposed on the brain can guide the analyses an interpretation of experimental data and the construction of mathematical models that attempt to make sense of how the brain works and how cognitive functions emerge. Development of these mathematical models for human-derived brain organoids offer an opportunity for testing new hypotheses about the human brain. When it comes to testing ideas about the brain that require a careful balance between experimental accessibility, manipulation, and complexity, in order to connect neurobiological details with higher level cognitive properties and clinical considerations, we argue that fundamental structure-function constraints applied to models of brain organoids offer a path forward. Moreover, we show these constraints appear in canonical and novel math models of neural activity and learning, and we make the case that constraint-based modeling and use of representations can bridge to machine learning for powerful mutual benefit. Copy rights belong to original authors. Visit the link for more info

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.06.25.172262v1?rss=1 Authors: Urresti, J., Zhang, P., Moran-Losada, P., Yu, N.-K., Negraes, P. D., Trujillo, C. A., Antaki, D., Amar, M., Chau, K., Pramod, A. B., Diedrich, J., Tejwani, L., Romero, S., Sebat, J., Yates, J. R., Muotri, A. R., Iakoucheva, L. M. Abstract: Reciprocal deletion and duplication of 16p11.2 is the most common copy number variation (CNV) associated with Autism Spectrum Disorders, and has significant effect on brain size. We generated cortical organoids to investigate neurodevelopmental pathways dysregulated by dosage changes of 16p11.2 CNV. We show that organoids recapitulate patients' macrocephaly and microcephaly phenotypes. Deletions and duplications have "mirror" effects on cell proliferation, neuronal maturation and synapse number, consistent with "mirror" effects on brain development in humans. Excess neuron number along with depletion of neural progenitors in deletions, and "mirror" phenotypes in duplications, demonstrate dosage-dependent impact of 16p11.2 CNV on early neurogenesis. Transcriptomic and proteomic profiling revealed synaptic defects and neuron migration as key drivers of 16p11.2 functional effect. Treatment with the RhoA inhibitor Rhosin rescued neuron migration. We implicate upregulation of small GTPase RhoA as one of the pathways impacted by the 16p11.2 CNV. This study identifies pathways dysregulated by the 16p11.2 CNV during early neocortical development. Copy rights belong to original authors. Visit the link for more info

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.05.30.125856v1?rss=1 Authors: Mesci, P., Macia, A., Saleh, A., Martin-Sancho, L., YIN, X., Snethlage, C., Avansini, S., Chanda, S., Muotri, A. Abstract: COVID-19 was rapidly declared a pandemic by the World Health Organization, only three months after the initial outbreak in Wuhan, China. Early clinical care mainly focused on respiratory illnesses. However, a variety of neurological manifestations in both adults and newborns are also emerging. To determine whether SARS-CoV-2 could target the human brain, we infected iPSC-derived human brain organoids. Our findings show that SARS-CoV-2 was able to infect and kill neural cells, including cortical neurons. This phenotype was accompanied by impaired synaptogenesis. Finally, Sofosbuvir, an FDA-approved antiviral drug, was able to rescue these alterations. Given that there are currently no vaccine or antiviral treatments available, urgent therapies are needed. Our findings put Sofosbuvir forward as potential treatments to alleviate COVID-19-related neurological symptoms. Copy rights belong to original authors. Visit the link for more info

Using brain organoids to understand neural development, learning computer science and engineering by building remotely controlled quadcopters, understanding geysers, high-tech approaches to sustainable agriculture, the work of the Berkeley Laboratories, and a very smart puppy, all on this edition of On Beyond. Series: "On Beyond" [Show ID: 35682]

Using brain organoids to understand neural development, learning computer science and engineering by building remotely controlled quadcopters, understanding geysers, high-tech approaches to sustainable agriculture, the work of the Berkeley Laboratories, and a very smart puppy, all on this edition of On Beyond. Series: "On Beyond" [Show ID: 35682]

Using brain organoids to understand neural development, learning computer science and engineering by building remotely controlled quadcopters, understanding geysers, high-tech approaches to sustainable agriculture, the work of the Berkeley Laboratories, and a very smart puppy, all on this edition of On Beyond. Series: "On Beyond" [Show ID: 35682]

Using brain organoids to understand neural development, learning computer science and engineering by building remotely controlled quadcopters, understanding geysers, high-tech approaches to sustainable agriculture, the work of the Berkeley Laboratories, and a very smart puppy, all on this edition of On Beyond. Series: "On Beyond" [Show ID: 35682]

Using brain organoids to understand neural development, learning computer science and engineering by building remotely controlled quadcopters, understanding geysers, high-tech approaches to sustainable agriculture, the work of the Berkeley Laboratories, and a very smart puppy, all on this edition of On Beyond. Series: "On Beyond" [Show ID: 35682]

Using brain organoids to understand neural development, learning computer science and engineering by building remotely controlled quadcopters, understanding geysers, high-tech approaches to sustainable agriculture, the work of the Berkeley Laboratories, and a very smart puppy, all on this edition of On Beyond. Series: "On Beyond" [Show ID: 35682]

A short summary of one of Discover Magazine's top-ten most significant science achievements of 2019 - the discovery of complex neural signals emerging in brain organoids by Alysson Muotri's lab at UC San Diego's Stem Cell Program. Series: "Stem Cell Channel" [Show ID: 35392]

A short summary of one of Discover Magazine's top-ten most significant science achievements of 2019 - the discovery of complex neural signals emerging in brain organoids by Alysson Muotri's lab at UC San Diego's Stem Cell Program. Series: "Stem Cell Channel" [Show ID: 35392]

A short summary of one of Discover Magazine's top-ten most significant science achievements of 2019 - the discovery of complex neural signals emerging in brain organoids by Alysson Muotri's lab at UC San Diego's Stem Cell Program. Series: "Stem Cell Channel" [Show ID: 35392]

A short summary of one of Discover Magazine's top-ten most significant science achievements of 2019 - the discovery of complex neural signals emerging in brain organoids by Alysson Muotri's lab at UC San Diego's Stem Cell Program. Series: "Stem Cell Channel" [Show ID: 35392]

A short summary of one of Discover Magazine's top-ten most significant science achievements of 2019 - the discovery of complex neural signals emerging in brain organoids by Alysson Muotri's lab at UC San Diego's Stem Cell Program. Series: "Stem Cell Channel" [Show ID: 35392]

A short summary of one of Discover Magazine's top-ten most significant science achievements of 2019 - the discovery of complex neural signals emerging in brain organoids by Alysson Muotri's lab at UC San Diego's Stem Cell Program. Series: "Stem Cell Channel" [Show ID: 35392]

Uma visão detalhada de um estudo conduzido pelo laboratório Alysson Muotri no Programa de Células-Tronco da UC San Diego, que encontrou o desenvolvimento de sinalização de redes complexas em organoides corticais humanos que parecem recapitular o desenvolvimento do cérebro fetal, oferecendo um modelo in vitro para estudar o desenvolvimento funcional de redes neuronais humanas. Series: "O Canal de Células-Tronco" [Spanish Language] [Show ID: 35153]

A detailed overview of a study conducted by Alysson Muotri's lab at the UC San Diego Stem Cell Program which found complex network signaling developing in human cortical organoids that appear to recapitulate fetal brain development, offering an in-vitro model to study functional development of human neuronal networks. Series: "Stem Cell Channel" [Science] [Show ID: 34267]

A detailed overview of a study conducted by Alysson Muotri's lab at the UC San Diego Stem Cell Program which found complex network signaling developing in human cortical organoids that appear to recapitulate fetal brain development, offering an in-vitro model to study functional development of human neuronal networks. Series: "Stem Cell Channel" [Science] [Show ID: 34267]

A detailed overview of a study conducted by Alysson Muotri's lab at the UC San Diego Stem Cell Program which found complex network signaling developing in human cortical organoids that appear to recapitulate fetal brain development, offering an in-vitro model to study functional development of human neuronal networks. Series: "Stem Cell Channel" [Science] [Show ID: 34267]

A detailed overview of a study conducted by Alysson Muotri's lab at the UC San Diego Stem Cell Program which found complex network signaling developing in human cortical organoids that appear to recapitulate fetal brain development, offering an in-vitro model to study functional development of human neuronal networks. Series: "Stem Cell Channel" [Science] [Show ID: 34267]

Brain organoids, or cortical organoids, hold much promise in finding interventions for neurological conditions, and have already proven useful in understanding the effects of Zika and rare neurological syndromes such as AGS. But how are they made? UC San Diego Stem Cell program project scientist Cleber Trujillo provides a brief overview of how the Muotri lab nurtures pluripotent stem cells into becoming brain organoids. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 34645]

Brain organoids, or cortical organoids, hold much promise in finding interventions for neurological conditions, and have already proven useful in understanding the effects of Zika and rare neurological syndromes such as AGS. But how are they made? UC San Diego Stem Cell program project scientist Cleber Trujillo provides a brief overview of how the Muotri lab nurtures pluripotent stem cells into becoming brain organoids. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 34645]

Os organoides cerebrais, ou organoides corticais, prometem grande sucesso na descoberta de intervenções para doenças neurológicas e têm comprovado sua utilidade na compreensão dos efeitos da Zika e síndromes neurológicas raras como a AGS. Mas como eles são produzidos? Cleber Trujillo, cientista do projeto do programa de células-tronco da Universidade da Califórnia em San Diego, oferece uma breve visão geral de como o laboratório Muotri cultiva células-tronco pluripotentes para que se tornem organoides cerebrais. Series: "O Canal de Células-Tronco" [Health and Medicine] [Science] [Spanish Language] [Show ID: 35061]

Investigadores en el Programa de Células Madre en UC San Diego han utilizado un raro desorden, Aicardi Goutieres (AGS), para explorar mecanismos fundamentales del cerebro. Utilizando organoides corticales, o cerebros en una placa, han seguido el neurodesarrollo a medida que encontraban nueva información sobre la relación entre los retrotransposones y la neuroinflamación. Series: "El Canal de Células Madre" [Health and Medicine] [Spanish Language] [Show ID: 32917]

Investigadores en el Programa de Células Madre en UC San Diego han utilizado un raro desorden, Aicardi Goutieres (AGS), para explorar mecanismos fundamentales del cerebro. Utilizando organoides corticales, o cerebros en una placa, han seguido el neurodesarrollo a medida que encontraban nueva información sobre la relación entre los retrotransposones y la neuroinflamación. Series: "El Canal de Células Madre" [Health and Medicine] [Spanish Language] [Show ID: 32917]

Pesquisadores do programa de células-tronco da Universidade da Califórnia em San Diego usaram uma doença rara, a Síndrome de Aicardi Goutieres (AGS), para investigar os mecanismos fundamentais do cérebro. Usando organóides corticais, ou cérebros, em um disco, eles monitoraram o neurodesenvolvimento enquanto descobriram novas informações sobre a correlação entre retrotransposão e neuroinflamação. Series: "O Canal de Células-Tronco" [Health and Medicine] [Spanish Language] [Show ID: 32916]

Pesquisadores do programa de células-tronco da Universidade da Califórnia em San Diego usaram uma doença rara, a Síndrome de Aicardi Goutieres (AGS), para investigar os mecanismos fundamentais do cérebro. Usando organóides corticais, ou cérebros, em um disco, eles monitoraram o neurodesenvolvimento enquanto descobriram novas informações sobre a correlação entre retrotransposão e neuroinflamação. Series: "O Canal de Células-Tronco" [Health and Medicine] [Spanish Language] [Show ID: 32916]

Researchers at the UC San Diego Stem Cell Program have used a rare disorder, Aicardi Goutieres (AGS), to explore fundamental brain mechanisms. By utilizing cortical organoids, or brains in a dish, they have tracked neurodevelopment while discovering new information about the relationship between retrotransposons and neuroinflammation. Series: "UCTV Prime" [Health and Medicine] [Show ID: 32743]

Researchers at the UC San Diego Stem Cell Program have used a rare disorder, Aicardi Goutieres (AGS), to explore fundamental brain mechanisms. By utilizing cortical organoids, or brains in a dish, they have tracked neurodevelopment while discovering new information about the relationship between retrotransposons and neuroinflammation. Series: "UCTV Prime" [Health and Medicine] [Show ID: 32743]

Researchers at the UC San Diego Stem Cell Program have used a rare disorder, Aicardi Goutieres (AGS), to explore fundamental brain mechanisms. By utilizing cortical organoids, or brains in a dish, they have tracked neurodevelopment while discovering new information about the relationship between retrotransposons and neuroinflammation. Series: "UCTV Prime" [Health and Medicine] [Show ID: 32743]

Researchers at the UC San Diego Stem Cell Program have used a rare disorder, Aicardi Goutieres (AGS), to explore fundamental brain mechanisms. By utilizing cortical organoids, or brains in a dish, they have tracked neurodevelopment while discovering new information about the relationship between retrotransposons and neuroinflammation. Series: "UCTV Prime" [Health and Medicine] [Show ID: 32743]

Cellular modeling may hold the key to unlocking some the most important questions about autism. Alysson R. Muotri, PhD joins William Mobley, MD, PhD to explain how his work is shedding light on not only the pathology of autism but potential new drugs. Series: "Autism Awareness Programs" [Health and Medicine] [Science] [Show ID: 31433]

Cellular modeling may hold the key to unlocking some the most important questions about autism. Alysson R. Muotri, PhD joins William Mobley, MD, PhD to explain how his work is shedding light on not only the pathology of autism but potential new drugs. Series: "Autism Awareness Programs" [Health and Medicine] [Science] [Show ID: 31433]

Cellular modeling may hold the key to unlocking some the most important questions about autism. Alysson R. Muotri, PhD joins William Mobley, MD, PhD to explain how his work is shedding light on not only the pathology of autism but potential new drugs. Series: "Autism Awareness Programs" [Health and Medicine] [Science] [Show ID: 31433]

Cellular modeling may hold the key to unlocking some the most important questions about autism. Alysson R. Muotri, PhD joins William Mobley, MD, PhD to explain how his work is shedding light on not only the pathology of autism but potential new drugs. Series: "Autism Awareness Programs" [Health and Medicine] [Science] [Show ID: 31433]

People with autism have difficulty with language and social interaction as if they are trapped inside their own brains. There is no cure. Dr. Alysson Muotri of UCSD devised a Fairy Tooth Kit Collection campaign in which autistic and unaffected kids could donate their baby teeth when they fell out. Using the induced pluripotent stem cell (iPS) technique, Muotri's team extracted pulp cells in the teeth and converted them into brain cells. The autistic brain cells showed distinct deficiencies in the petri dish which could be reversed. In this seminar presented to the governing Board of California's Stem Cell Agency, Dr. Muotri describes these results in more detail. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 28241]

People with autism have difficulty with language and social interaction as if they are trapped inside their own brains. There is no cure. Dr. Alysson Muotri of UCSD devised a Fairy Tooth Kit Collection campaign in which autistic and unaffected kids could donate their baby teeth when they fell out. Using the induced pluripotent stem cell (iPS) technique, Muotri's team extracted pulp cells in the teeth and converted them into brain cells. The autistic brain cells showed distinct deficiencies in the petri dish which could be reversed. In this seminar presented to the governing Board of California's Stem Cell Agency, Dr. Muotri describes these results in more detail. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 28241]

Dr. Alysson Muotri, a leading cellular and molecular biologist, talks about recent advances in medicine that are making it possible to find medicines that can change the way autistic brain cells react, grow and take in new information.  This research has the potential to phenotype Autism and make existing treatments more effective and efficient. For more information on Dr. Muotri’s research visit:  Http://muotri.ucsd.edu    Autism Live is a production of the Center for Autism and Related Disorders (CARD), headquartered in Tarzana, California, and with offices throughout, the United States and around the globe. For more information on therapy for autism and other related disorders, visit the CARD website at http://centerforautism.com