Podcasts about detecting

Dr. Diana Bianchi, a former March of Dimes Basil O'Connor Starter Scholar Research Award winner, discusses the ability of prenatal testing to detect maternal cancer, her discovery of microchimerism, a potential prenatal therapeutic for Down syndrome, and whether the subjects in Vermeer's paintings were pregnant. This episode was recorded March 4, 2025. As of the episode air date in May 2025, Dr. Bianchi no longer held the position of director of the National Institute of Child Health and Human Development (NICHD).

In de podcastserie Proefschriften spreekt aios interne geneeskunde dr. Tessa Steenbruggen met promovendi. In deze speciale aflevering spreekt zij met dr. Paul Hengeveld over zijn proefschrift, getiteld: ‘Molecular risk stratification in chronic lymphocytic leukemia'. Paul vertelt hoe moleculaire risicostratificatie kan helpen in voorspellen van de prognose van patiënten met chronische lymfatische leukemie (CLL) en filosofeert over de toekomst van MRD (measurable residual disease) bij CLL. Paul heeft 27 maart 2024 zijn proefschrift succesvol verdedigd aan de Erasmus Universiteit bij prof. dr. Ton Langerak en co-promotoren dr. Mark-David Levin en dr. Peter Westerweel. Hij kreeg dit jaar tijdens de hematologiedagen het Jaap Steenbergen Stipendium voor het beste hematologieproefschrift van 2024.Referenties Inspiratietip: Belgische televisieserie - Met gevoel voor tumor Prognose CLL – THEMIS2 MRD CLL10 Sequentiële MRD HOVON-139 FLAIR-studie

The news last week of former President Joe Biden's advanced prostate cancer has more people thinking and talking about the condition.About 1 in 8 men in the U.S. are diagnosed with prostate cancer at some point in their lives. It's the most-diagnosed cancer in men and the second-leading cause of cancer-related death in American men after lung cancer. That's according to the American Cancer Society.In this installment of our series, "In Good Health," we talk about how to detect and treat prostate cancer. Then, we switch gears to talk about the Food and Drug Administration's plans to potentially restrict access to the COVID-19 vaccine.Want to support 1A? Give to your local public radio station and subscribe to this podcast. Have questions? Connect with us. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

Dan Brahmy, Co-Founder and CEO at Cyabra, discusses the cutting-edge in disinformation monitoring. Dan shares some of Cyabra's work around the new pope, the tariff war, and narratives following the Trump assassination attempt. We discuss how monitoring works technically, what type of attributes are used to classify accounts as inauthentic, and how source attribution can be identified through patterns. Special thanks to Jill Burkes, PR and Communications lead at Cyabra, for setting up and contributing to the episode!  Here's the link to Cyabra's newsletter.

Join Dr. Stephanie and Dr. Saulnier as they discuss her presentation at the Converge Autism Summit on broadening the autism spectrum.https://nacsatl.com/They will discuss:The key features of autismHow Autism symptoms are expressed differently in male and femaleThe role of racial, ethnic, and socioeconomic disparities in misdiagnosis of autismCommon overlaps and differential diagnosisDr. Saulnier obtained her doctorate in Clinical Psychology from the University of Connecticut. She trained and worked at the Yale Child Study Center's Autism Program for nearly a decade before relocating to Emory University School of Medicine and the Marcus Autism Center in Atlanta, GA, where she directed a large-scale clinical research program. In 2018, she opened her own company, Neurodevelopmental Assessment & Consulting Services, where she specializes in diagnostic assessment, as well as teaching and training for autism spectrum and related disorders. Dr. Saulnier has published over 50 articles, written two books, and she is an author on the Vineland Adaptive Behavior Scales, Third Edition.Looking for Assessment in GA? https://www.psychologytoday.com/us/therapists/neurodevelopmental-assessment-consulting-svc-decatur-ga/409874

Excited is overused This week, we recap Microsoft Build, Google I/O, and Java turning 30. Plus, more Vegemite talk and a discussion on whether tech presenters really need to tell us they're “excited.” Watch the YouTube Live Recording of Episode (https://www.youtube.com/live/4ar2nzlx3gw?si=pee9R6HbHN06etA2) 520 (https://www.youtube.com/live/4ar2nzlx3gw?si=pee9R6HbHN06etA2) Runner-up Titles We all need choices Vegans are against everything The problem is you shouldn't be watching keynotes You're giving the black box too much responsibility What are you going to do? Some more stuff they announced that I don't want They're excited about that Hopefully people are excited about that I'm happy for you I want to like it Nerd famous Can you just fix calendaring? It's too much I'm not going back to Java Rundown Will Matt try marmalade with his Vegemite for the full PBJ analogue. (https://bsky.app/profile/thescarletmanuka.bsky.social/post/3lpdioobdek27) MSFT Build Microsoft Build 2025: news and announcements from the developer conference (https://www.theverge.com/news/669382/microsoft-build-2025-news-ai-agents) Microsoft announces over 50 AI tools to build the ‘agentic web' at Build 2025 (https://venturebeat.com/ai/microsoft-announces-over-50-ai-tools-to-build-the-agentic-web-at-build-2025/) Findings from Microsoft's 3-week study on Copilot use (https://newsletter.getdx.com/p/microsoft-3-week-study-on-copilot-impact) Microsoft open sources Windows Subsystem for Linux (https://www.theregister.com/2025/05/19/microsoft_wsl_open_source/) Google I/O Everything announced at the Google I/O 2025 keynote (https://www.engadget.com/ai/everything-announced-at-the-google-io-2025-keynote-171514495.html?guccounter=1&guce_referrer=aHR0cHM6Ly9uZXdzLmdvb2dsZS5jb20v&guce_referrer_sig=AQAAAIewjPeuiVydyPgPtFxJyD7lYSE7rAY-BFM7JxN5AHvJvH_NrHmCURfrSuBK4HmB700OTDoGERdfPyB77mCb8_225GPcoppCXG4dl_bgGOA9j4E5Fprl_nUD__-69yEG5-W7vmXISAdJC2kBU3MSZErnX1TuyR1_gKfb5Hx_OdRs) Android XR is getting stylish partners in Warby Parker and Gentle Monster (https://www.theverge.com/google-io/670013/android-xr-warby-parker-gentle-monster-smart-glassesi-io-2025) Jules - An Asynchronous Coding Agent (https://jules.google/) Google Embraces MCP (https://thenewstack.io/google-embraces-mcp/?link_source=ta_bluesky_link&taid=682cf46509703200019ca4f3&utm_campaign=trueanthem&utm_medium=social&utm_source=bluesky) iOS 19 Will Let Developers Use Apple's AI Models in Their Apps (https://www.macrumors.com/2025/05/20/ios-19-apple-ai-models-developers/) NEW Claude MCP AI Super Agents (https://x.com/juliangoldieseo/status/1924148362653348232?s=46&t=zgzybiDdIcGuQ_7WuoOX0A) AWS Launches Its Take on an Open Source AI Agents SDK (https://thenewstack.io/aws-launches-its-take-on-an-open-source-ai-agents-sdk/) Java at 30: The Genius Behind the Code That Changed Tech (https://thenewstack.io/java-at-30-the-genius-behind-the-code-that-changed-tech/) Relevant to your Interests If AI is so good at coding … where are the open source contributions? (https://pivot-to-ai.com/2025/05/13/if-ai-is-so-good-at-coding-where-are-the-open-source-contributions/) Y Combinator says Google is a ‘monopolist' that has ‘stunted' the startup ecosystem (https://techcrunch.com/2025/05/13/y-combinator-says-google-is-a-monopolist-that-has-stunted-the-startup-ecosystem) Coinbase says customers' personal information stolen in data breach (https://techcrunch.com/2025/05/15/coinbase-says-customers-personal-information-stolen-in-data-breach/) DataBricks interview about Neon (https://www.axios.com/newsletters/axios-pro-rata-a6f0b4f0-fe7f-412f-bf4b-5978de02d604.html?chunk=1&utm_term=emshare#story1) OpenAI launches Codex, an AI coding agent, in ChatGPT (https://techcrunch.com/2025/05/16/openai-launches-codex-an-ai-coding-agent-in-chatgpt/) CarPlay Ultra, the next generation of CarPlay, begins rolling out today (https://www.apple.com/newsroom/2025/05/carplay-ultra-the-next-generation-of-carplay-begins-rolling-out-today/) Meta argues enshittification isn't real in bid to toss FTC monopoly case (https://arstechnica.com/tech-policy/2025/05/meta-says-no-proof-of-monopoly-power-wants-ftc-case-dismissed-mid-trial/) When Open Source Isn't: How OpenRewrite Lost Its Way (https://medium.com/@jonathan.leitschuh/when-open-source-isnt-how-openrewrite-lost-its-way-642053be287d) Wiz 2.0? Cyera's meteoric $6B valuation is turning heads across the cyber world | CTech (https://www.calcalistech.com/ctechnews/article/shavjm2g2) Steve Langasek, One of Ubuntu Linux's Leading Lights, Has Died (https://thenewstack.io/steve-langasek-one-of-ubuntu-linuxs-leading-lights-has-died/) Python: The Documentary [OFFICIAL TRAILER] (https://www.youtube.com/watch?v=pqBqdNIPrbo) Spain Orders Airbnb to Take Down 66,000 Rental Listings (https://www.nytimes.com/2025/05/19/business/airbnb-listings-spain.html) Detecting malicious Unicode (https://daniel.haxx.se/blog/2025/05/16/detecting-malicious-unicode/) Former Apple Design Guru Jony Ive to Take Expansive Role at OpenAI (https://www.wsj.com/tech/ai/former-apple-design-guru-jony-ive-to-take-expansive-role-at-openai-5787f7da) Apple's Worldwide Developers Conference kicks off June 9 (https://www.apple.com/newsroom/2025/05/apples-worldwide-developers-conference-kicks-off-june-9/) Valkey Turns One: How the Community Fork Left Redis in the Dust - Momento (https://www.gomomento.com/blog/valkey-turns-one-how-the-community-fork-left-redis-in-the-dust/?ck_subscriber_id=512834888&utm_source=convertkit&utm_medium=email&utm_campaign=[Last%20Week%20in%20AWS]:%20Transform%20Away,%20as%20AWS%20Reverses%20Course%20-%2017665354) Nonsense Max (@StreamOnMax) on X (https://x.com/StreamOnMax/status/1922781490473034153) Uber to introduce fixed-route shuttles in major US cities designed for commuters (https://techcrunch.com/2025/05/14/uber-to-introduce-fixed-route-shuttles-in-major-us-cities-other-ways-to-save/) Conferences POST/CON 25 (https://postcon.postman.com/2025/), June 3-4, Los Angeles, CA, Brandon representing SDT. Register here for free pass (https://fnf.dev/43irTu1) using code BRANDON (https://fnf.dev/43irTu1) (limited to first 20 People) Contract-Driven Development: Unite Your Teams and Accelerate Delivery (https://postcon.postman.com/2025/session/3022520/contract-driven-development-unite-your-teams-and-accelerate-delivery%20%20%20%20%20%208:33) by Chris Chandler SREDay Cologne, June 12th, 2025 (https://sreday.com/2025-cologne-q2/#tickets) - Coté speaking, discount: CLG10, 10% off. SDT News & Community Join our Slack community (https://softwaredefinedtalk.slack.com/join/shared_invite/zt-1hn55iv5d-UTfN7mVX1D9D5ExRt3ZJYQ#/shared-invite/email) Email the show: questions@softwaredefinedtalk.com (mailto:questions@softwaredefinedtalk.com) Free stickers: Email your address to stickers@softwaredefinedtalk.com (mailto:stickers@softwaredefinedtalk.com) Follow us on social media: Twitter (https://twitter.com/softwaredeftalk), Threads (https://www.threads.net/@softwaredefinedtalk), Mastodon (https://hachyderm.io/@softwaredefinedtalk), LinkedIn (https://www.linkedin.com/company/software-defined-talk/), BlueSky (https://bsky.app/profile/softwaredefinedtalk.com) Watch us on: Twitch (https://www.twitch.tv/sdtpodcast), YouTube (https://www.youtube.com/channel/UCi3OJPV6h9tp-hbsGBLGsDQ/featured), Instagram (https://www.instagram.com/softwaredefinedtalk/), TikTok (https://www.tiktok.com/@softwaredefinedtalk) Book offer: Use code SDT for $20 off "Digital WTF" by Coté (https://leanpub.com/digitalwtf/c/sdt) Sponsor the show (https://www.softwaredefinedtalk.com/ads): ads@softwaredefinedtalk.com (mailto:ads@softwaredefinedtalk.com) Recommendations Brandon: MurderBot (https://www.google.com/aclk?sa=L&ai=DChcSEwi286yM0KiNAxUELNQBHStVDhgYABABGgJvYQ&co=1&gclid=Cj0KCQjwxJvBBhDuARIsAGUgNfjytNAoEF2oBZYZixtUoB15h1o0UU1SJRQp-A-GFE_i0FGLHOE5wY8aAoFzEALw_wcB&cce=1&sig=AOD64_3mm-tO-giOK7S1lj45fNCC7pw-6w&q&adurl&ved=2ahUKEwiFq6eM0KiNAxXI4ckDHc0cBAMQ0Qx6BAg9EAE)

“Ten years ago, there were relatively few treatment options [for bladder cancer] compared to what we have today which is a relative wealth of options,” said Debasish Sundi, MD, a James urologist and bladder cancer specialist. In this episode, Dr. Sundi explained the function of the bladder (storing urine), the different types of bladder cancer (contained within the bladder and metastatic), how new immunotherapies have led to better options and outcomes, and his research which focuses on identifying the biomarkers in a patient's bladder cancer by analyzing their urine, instead of a more invasive procedure using a scope. There are about 80,000 new cases of bladder cancer diagnosed ever year in the United States and “about 75 to 80 percent are in males,” Dr. Sundi said, adding “the number one cause is exposure to tobacco smoke and tobacco products.” The primary symptom is blood in the urine. “If you see blood in your urine, even if it's just pink, it is worthwhile to talk to your primary care doctor or see a urologist.” Clinical trials have led to the development and approval of several new immunotherapy treatments. “The challenge is we do not have any good biomarkers to tell us how our patients will respond,” Dr. Sundi said. “My lab is developing an assay [test] to non-invasively make an assessment. We've learned that if we look at the immune cells in the urine of someone with bladder cancer, they are similar to the immune cells in their tumor … And this could lead to significantly improving the therapeutic options and helping doctors pick the best medicine for their patients from the start.” Dr. Sundi said his research is motivated by his patients. “When I started in this field the experiences of patients with bladder cancer was something we could and should improve,” he said. “Working toward this is the fuel that is self-sustaining and there is so much excitement in terms of the innovation happening in the bladder-cancer field.”

BUFFALO, NY – May 19, 2025 – A new #research paper was #published in Volume 16 of Oncotarget on May 9, 2025, titled “Analytical validation of a circulating tumor DNA assay using PhasED-Seq technology for detecting residual disease in B-cell malignancies.” In this study, a team from Foresight Diagnostics led by first author Nina Klimova and corresponding author Laura Hyland validated a new DNA-based blood test designed to detect minimal residual disease (MRD) in patients with B-cell cancers. This assay uses a highly sensitive method called Phased Variant Enrichment and Detection Sequencing (PhasED-Seq) to find tiny fragments of tumor DNA in the blood. Its ultra-sensitive detection capabilities offer a powerful tool for early cancer detection, monitoring treatment response, and predicting cancer reappearance. B-cell lymphomas, such as diffuse large B-cell lymphoma (DLBCL), are among the most prevalent blood cancers. Although many patients respond to initial treatment, up to 40% relapse. Standard monitoring methods such as imaging scans often miss low levels of cancer cells, creating a need for more precise tools. This study introduces a non-invasive blood test that improves the detection of MRD, a critical factor in guiding follow-up care and early intervention. The test works by tracking unique groups of mutations known as phased variants in tumor DNA. These mutations are more specific to cancer and allow for highly accurate identification of tumor fragments in the bloodstream. The PhasED-Seq-based MRD assay was tested on three types of samples. First, blood plasma from healthy individuals was used to confirm the test does not give false positives. Second, researchers created controlled samples by mixing tumor DNA from lymphoma patients with healthy DNA to measure how sensitive and precise the test is. Finally, blood samples from patients with B-cell lymphoma were used to compare the new test to an existing method. Across all sample types, the PhasED-Seq-based MRD assay demonstrated exceptional performance—capable of detecting fewer than one cancer DNA molecule per million normal DNA fragments. It also demonstrated a very low false positive rate and over 96% reproducibility across different laboratory conditions. Compared to an existing method, the new PhasED-Seq assay showed more than 90% agreement in positive results and nearly 78% agreement in negative results. In cases where the tests disagreed, the new method aligned more closely with actual clinical outcomes, including whether patients relapsed or stayed in remission. “The background error rate of the PhasED-Seq-based MRD assay was 1.95E-08, or 1.95 mutant molecules in 100 million informative molecules.” The findings support the use of PhasED-Seq-based MRD assays in routine clinical practice. It could be especially useful for identifying patients who need additional treatment even when imaging results appear normal. This aligns with updated clinical guidelines that encourage the use of blood-based DNA tests to supplement traditional scans in lymphoma care. This study offers strong evidence that the PhasED-Seq-based MRD assay is a precise, reliable, and clinically relevant tool. By detecting signs of cancer earlier and more accurately, it may help clinicians tailor treatments to individual patients and improve long-term outcomes in B-cell malignancies. DOI - https://doi.org/10.18632/oncotarget.28719 Correspondence to - Laura Hyland - laura.hyland@foresight-dx.com Video short - https://www.youtube.com/watch?v=8hdh3G5zvlc Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Julie (SP/SO 1w2 126) says being an Enneagram One is like trying to control the lightning bolt you're riding. We talk about how her pursuit of competence — in painting, music, and even dog training — brought early success but gradually drained the joy from each pursuit. She shares what it's like to live in a body wired for precision and pressure, and how that rigidity eventually led to serious health issues after she threw herself into an activist cause. We explore how she navigates moral complexity not through rules, but through a somatic “yes,” and how her 2-fix allows her to “see people's souls.” Throughout the conversation, she highlights something rarely said about Ones: their sharp, absurd sense of humor that helps her stay connected to lightness and levity. LINKSLearn at The Enneagram School https://theenneagramschool.com/ Intro Course https://www.theenneagramschool.com/intro-enneagram-course Get Typed https://www.enneagrammer.com/ Sinsomnia Podcast (Dreams) https://podcasts.apple.com/us/podcast/sinsomnia/id1684154994 House of Enneagram https://www.youtube.com/@houseofenneagram TIMESTAMPS 00:00 - Intro 03:04 - Julie's journey as an artist 17:51 - Creativity and excellence as a Type 1 22:43 - 1's rigidity in music 28:52 - Being a frustration type in the body center 31:44 - 1w2 “rightness of action” 34:18 - Type 2/2fix “tracking emotional data points” 44:08 - Casting judgment or seeing soul? 49:27 - Julie's relationship to criticality 57:26 - Advocacy at the expense of personal health 1:00:47 - “Primordial Perfection” 1:04:43 - Detecting anxiety as a body type 1:08:23 - The humor and absurdism of 1 1:17:25 - Outro CREDITS Interview by Josh Lavine Edited by Kristen Oberly Music by Coma-Media from Pixabay Coma-Media: https://pixabay.com/users/coma-media-24399569/ Pixabay: https://pixabay.com/ --- #enneagram #enneagramtypes #enneagram1

A digital tool that uses artificial intelligence to analyze speech patterns could help doctors detect dementia in patients when other signs and symptoms are not perceptible.

The beginnings of our end — where the anus came from Our distant evolutionary ancestors had no anuses. Their waste was excreted from the same orifice they used to ingest food, much like jellyfish do today. Now a new study on bioRxiv that has yet to be peer-reviewed, scientists think they've found the evolutionary link in a worm with only a single digestive hole. Andreas Hejnol, from Friedrich Schiller University Jena, said he found genes we now associate with the anus being expressed in the worms in the opening where its sperm comes out, suggesting that in our evolutionary history a similar orifice was co-opted as a butt hole. Deepfake videos are becoming so real, spotting them is becoming increasingly diceyDetecting deepfake videos generated by artificial intelligence is a problem that's getting progressively worse as the technology continues to improve. One way we used to be able to tell the difference between a fake and real video is that subtle signals revealing a person's heart rate don't exist in artificially generated videos. But that is no longer the case, according to a new study in the journal Frontiers in Imaging. Peter Eisert, from Humboldt University and the Fraunhofer Heinrich-Hertz-Institute HHI in Germany, said detecting manipulated content visually is only going to become a lot more difficult going forward. Crows can use tools, do math — and now apparently understand geometryCrows are known to be among the most intelligent of animals, and a new study has explored their geometrical sophistication. Researchers including Andreas Nieder from the University of Tübingen found that crows can recognize and distinguish different kinds of quadrilateral shapes, an ability we had thought was unique to humans. The research was published in the journal Science Advances.There's gold in them thar magnetically charged neutron stars!Astronomers have discovered a new source of the universe's heavy elements — things like gold, platinum and uranium. A study led by astrophysicist Anirudh Patel found that magnetars — exotic neutron stars with ultra-powerful magnetic fields — may produce these elements in a process analogous to the way solar flares are produced by our Sun. The research, published in The Astrophysical Journal Letters, found that a single flare from a magnetar could produce the mass equivalent of 27 moons' worth of these heavy elements in one burst.It may not be big, but it's small — and stroppyYou might not expect an insect so tiny you need a magnifying glass to see it properly to be an aggressive defender of its territory, but that's because you haven't met the warty birch caterpillar. Its territory is just the tip of a birch leaf, but it defends it by threatening intruders with vigorous, if not precisely powerful, vibrations. Jayne Yack at Carleton University has been studying this caterpillar since 2008. This research was published in the Journal of Experimental Biology.Criminals beware — the microbiome leaves fingerprintsScientists have developed a new tool that can track location based on traces of the bacteria characteristic to different places. Eran Elhaik, from Lund University in Sweden, trained the AI tool using nearly 4,500 microbiome samples collected around the world from subway systems, soil and the oceans. He said they could identify the city source in 92 per cent of their urban samples, and in Hong Kong, where a lot of their data came from, they could identify the specific subway station samples were taken from with 82 per cent accuracy. The study was published in the journal Genome Biology and Evolution.

Our 208th episode with a summary and discussion of last week's big AI news! Recorded on 05/02/2025 Hosted by Andrey Kurenkov and Jeremie Harris. Feel free to email us your questions and feedback at contact@lastweekinai.com and/or hello@gladstone.ai Read out our text newsletter and comment on the podcast at https://lastweekin.ai/. Join our Discord here! https://discord.gg/nTyezGSKwP In this episode: OpenAI showcases new integration capabilities in their API, enhancing the performance of LLMs and image generators with updated functionalities and improved user interfaces. Analysis of OpenAI's preparedness framework reveals updates focusing on biological and chemical risks, cybersecurity, and AI self-improvement, while tone down the emphasis on persuasion capabilities. Anthropic's research highlights potential security vulnerabilities in AI models, demonstrating various malicious use cases such as influence operations and hacking tool creation. A detailed examination of AI competition between the US and China reveals China's impending capability to match the US in AI advancement this year, emphasizing the impact of export controls and the importance of geopolitical strategy. Timestamps + Links: Tools & Apps (00:02:57) Anthropic lets users connect more apps to Claude (00:08:20) OpenAI undoes its glaze-heavy ChatGPT update (00:15:16) Baidu ERNIE X1 and 4.5 Turbo boast high performance at low cost (00:19:44) Adobe adds more image generators to its growing AI family (00:24:35) OpenAI makes its upgraded image generator available to developers (00:27:01) xAI's Grok chatbot can now ‘see' the world around it Applications & Business: (00:28:41) Thinking Machines Lab CEO Has Unusual Control in Andreessen-Led Deal (00:33:36) Chip war heats up: Huawei 910C emerges as China's answer to US export bans (00:34:21) Huawei to Test New AI Chip (00:40:17) ByteDance, Alibaba and Tencent stockpile billions worth of Nvidia chips (00:43:59) Speculation mounts that Musk will raise tens of billions for AI supercomputer with 1 million GPUs: Report Projects & Open Source: (00:47:14) Alibaba unveils Qwen 3, a family of ‘hybrid' AI reasoning models (00:54:14) Intellect-2 (01:02:07) BitNet b1.58 2B4T Technical Report (01:05:33) Meta AI Introduces Perception Encoder: A Large-Scale Vision Encoder that Excels Across Several Vision Tasks for Images and Video Research & Advancements: (01:06:42) The Leaderboard Illusion (01:12:08) Does Reinforcement Learning Really Incentivize Reasoning Capacity in LLMs Beyond the Base Model? (01:18:38) Reinforcement Learning for Reasoning in Large Language Models with One Training Example (01:24:40) Sleep-time Compute: Beyond Inference Scaling at Test-time Policy & Safety: (01:28:23) Every AI Datacenter Is Vulnerable to Chinese Espionage, Report Says (01:32:27) OpenAI preparedness framework update (01:38:31) Detecting and Countering Malicious Uses of Claude: March 2025 (01:46:33) Chinese AI Will Match America's

About 1 in 10 dogs will develop heart disease, and though it's less common…

About 1 in 10 dogs will develop heart disease, and though it's less common in cats, they're at risk too. That's why heart disease should be on every pet parent's...

Tom Zaubler, MD, continues sharing his insights on AI's applications in the field of behavioral healthcare, emphasizing the technology's ability to identify which patients are at high risk for suicide. Let us know what you thought of this week's episode on Twitter: @physicianswkly Want to share your medical expertise, research, or unique experience in medicine on the PW podcast? Email us at editorial@physweekly.com! Thanks for listening!

What happens when a hedge fund veteran loses his sister to cancer and dedicates the rest of his life to stopping the disease in its tracks?On this powerful episode of the Crackin' Backs Podcast, we sit down with Sumit Rai, founder and CEO of Cancer Check Labs—a revolutionary company on the forefront of early cancer detection. After two decades in venture capital and hedge funds, Sumit's life took a personal and urgent turn in 2012 when he lost his only sibling to cancer. That loss sparked a mission that now spans cutting-edge diagnostics, bold technological innovation, and a commitment to public health that's as personal as it is professional.We explore:How Cancer Check Labs is changing the cancer conversation with blood tests capable of detecting cancer at Stage 0—before a tumor even forms.The psychological challenges of early detection: When is early too early? And how do we avoid panic and instead inspire action?The emerging concept of “dialysis for cancer”—a mind-blowing technology in development that could filter cancer cells directly from the bloodstream.Why Sumit's approach outpaces earlier tools like Cologuard in both precision and peace of mind.How the post-pandemic world views health tech, and what it takes to earn the trust of both patients and physicians.The “Save a Firefighter” initiative, a nonprofit offering free cancer screenings to our front-line heroes—where 72% of line-of-duty deaths are cancer-related.And most importantly, we look ahead to a future where routine, multi-cancer blood screening could become as normal as checking your cholesterol—a future where knowledge saves lives, and where fear gives way to empowerment. Learn more about Cancer Check Labs and schedule your screening: https://cancerchecklabs.com Special Offer for Our Listeners:Save $200 on your test by using code: Crackin200 at checkout.Offer valid until July 10, 2025.Claim your discount here: https://cancerchecklabs.comWe are two sports chiropractors, seeking knowledge from some of the best resources in the world of health. From our perspective, health is more than just “Crackin Backs” but a deep dive into physical, mental, and nutritional well-being philosophies. Join us as we talk to some of the greatest minds and discover some of the most incredible gems you can use to maintain a higher level of health. Crackin Backs Podcast

Join Donna & Adrian with YouTuber Miss Detectorist 'Ellie' based in Devon who combines her passions for metal detecting, landscape art, and filmmaking to explore our rich history.Become a supporter of this podcast: https://www.spreaker.com/podcast/the-big-detecting-show--3690873/support.

Join Donna and Adrian to speak with Jelly on her recent bucket lister and also charity event she is entering soon. Dave will be back soon

Join us with Luke from Swing & Dig to discuss his range of metal detecting accessories and some new products. Plus all the other fun and entertaining bits that come with the show!Become a supporter of this podcast: https://www.spreaker.com/podcast/the-big-detecting-show--3690873/support.

Who digs iron when metal detecting...? Join Donna and Adrian to discuss why we should possibly be digging more iron when out in the field.Become a supporter of this podcast: https://www.spreaker.com/podcast/the-big-detecting-show--3690873/support.

John O'Trakoun and Adam Scavette discuss their new approach to gauging the health of the economy and the likelihood that a recession is taking place before other indicators would detect it. O'Trakoun is a senior policy economist at the Federal Reserve Bank of Richmond and Scavette is a community development economic advisor at the Federal Reserve Bank of Philadelphia. Full transcript and related links: https://www.richmondfed.org/podcasts/speaking_of_the_economy/2025/speaking_2025_04_16_sos_recession_indicator

Dr. Andy Hoofnagle is a researcher, professor, board certified pathologist, and laboratory director at the University of Washington. He is Head of the Division of Chemistry, Director of Chemistry at the UW Medical Center - Montlake, Director of Clinical Mass Spectrometry, and Director of the Nutrition Obesity Research Center's Analytic Core at the University of Washington. He is also Chair of the PCC's Collagen Turnover Working Group. In this episode, he discusses his research and recent advances in the ability to detect growth hormone administration using biomarkers of collagen turnover. We also discussed Dr. Hoofnagle's role as a mentor for PCC Research Fellow Dr. Huu Hien Huynh and his experience as a presenter at our 2025 PCC Conference. 

What does it take to go from humble beginnings to billionaire status while revolutionizing health and technology? In this episode of The Thrive State Podcast, Dr. Kien Vuu sits down with Naveen Jain, the visionary entrepreneur behind Viome, Moon Express, and other billion-dollar companies, to discuss mindset, health, AI, and longevity.   Episode Highlights: From rags to billionaire – Meet Naveen Jain The #1 mindset shift that makes success inevitable Why entrepreneurs should never compete—only disrupt How AI is transforming healthcare (Detecting disease before symptoms appear!) The gut-brain connection and how it impacts mental health

It's been a few months since wildfires devastated Los Angeles, and some people are just now starting the long process of repairing and rebuilding their homes. But mixed into the soot and ash can be some hidden dangers, including lead, asbestos, arsenic and lithium. These toxic materials were used to build those homes and got blown across LA. Scientists from the California Institute of Technology have been investigating this invisible danger, testing more than 50 homes for these contaminants. And one of those homes belongs to the lead scientist behind the study. Reporter Caroline Champlin has more.  And our series on Californians and resilience continues with twenty-five-year-old Brittianna Robinson. She experienced sexual abuse and trafficking as a child. Robinson credits her faith in God and support from mentors and her church for helping her find a path forward. Today, she uses her lived experience to help other commercially sexually exploited children (CSEC) as an advocate on the Los Angeles County Youth Commission. Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode I am joined by Lorna Byrne, spiritual teacher and best selling author of “Angels in my Hair”. Lorna describes her childhood in Ireland when she first began to see and interact with angels and souls of the dead, and recalls how she navigated these visionary experiences. Lorna discusses the different types of angels that she sees, as well as other beings such as souls of the deceased, land spirits, elementals and more, and how others might learn to see as she does. Lorna also reflects on feeling the energy of a place; her lifelong experience of being different to others; unusual reactions people have towards her; and the importance of love, hope, and compassion. … Video version: https://www.guruviking.com/podcast/ep301-angels-in-my-hair-lorna-byrne | Also available on Youtube, iTunes, & Spotify – search ‘Guru Viking Podcast'. … Topics include: 00:00 - Intro 00:52 - Growing up different 04:17 - Learning from angels 05:27 - Be your unique self 06:36 - Seeing angels physically 07:50 - Holding things back and confusion about mankind 09:07 - Consulted by clerics, theologians, and academics 10:04 - Is God real? 11:32 - Responses from people all over the world 13:02 - Deep interactions with strangers 15:20 - Lorna's view of human beings 16:39 - Can anyone see angels and spirits? 19:10 - Being open to new knowledge 21:39 - Intertwining of the human body and soul 23:43 - Everything is possible 25:57 - Has Lorna met others who can see angels? 28:32 - People who pretend to see spirits for money 39:37 - Feeling the energy of a place 30:35 - Local traditions, land spirits, and the range of beings Lorna encounters 35:59 - How to see spirits 37:53 - The Spirit of the Water 39:52 - Everything has energy 41:51 - Angel at the Centre of the Earth 43:25 - Detecting the influence of Satan 45:59 - A story of boy soldiers 49:06 - Cycles of abuse 50:12 - Thoughts about the future of mankind 52:50 - Love, hope, and compassion 54:43 - Lorna's retreat centre, Sanctuary 
… Find our more about Lorna Byrne: - https://lornabyrne.com/ - … For more interviews, videos, and more visit: - https://www.guruviking.com Music ‘Deva Dasi' by Steve James

This week AmSpa founder and CEO, Alex R. Thiersch, JD, speaks with Bobbi Bullock, NP-C, founder of Bobbi Bullock Medical Esthetics. They talk about how she got her start in medical aesthetics, the unique health challenge that led her to groundbreaking research on facial asymmetry, and how she builds community to grow stronger together. Listen to hear more about: How she got into aesthetic medicine from corporate health care; Going from one room in a salon to growing a fully booked business; Prosopagnosia: overcoming the challenge to detect and correct asymmetries; Identifying asymmetry in the nasolabial folds, lips, cheeks, jawline and temple; How her network saved the day when she experienced a vascular occlusion; Promoting community and collaboration with a network of med spas; And more! Hear more about Bullock's experiences in the All-Star Injectors Panel on Friday, April 11 at Medical Spa Show. --- Music by Ghost Score

It's unsettling how some people know exactly how to exploit kindness and trust. Dr. David Snyder breaks down the sneaky psychological tricks used by manipulators—things like truth bias and emotional grooming. He explains how these predators profile victims, target insecurities, and build fake emotional bonds to control and use them. His five-phase breakdown exposes how empathy becomes a trap. Knowing these tactics is the first step to spotting and stopping manipulation before it takes over your life.Standout Quotes:• “Vulnerability equals suggestibility. The more vulnerable you can make somebody feel, the more suggestible they become.” – Dr. David Snyder• “Every nervous system is selfish. It's moving through the world looking for itself.” – Dr. David Snyder• “When in doubt, echo it out. Everything goes back to echoing.” – Dr. David Snyder• “Sociopathic people know right from wrong. They know what society says is right. They don't care.” – Dr. David Snyder• “People don't fall victim to lies because they're fooled. They fall victim to deceit because they need to believe the lie.” – Dr. David SnyderKey Takeaways:• Audit your personal vulnerabilities by honestly checking how many items on the predator's victim profile you match, then strategically work to strengthen those weak points in your psychological armor.• Practice the echo technique in low-stakes conversations to understand how mirroring language and emotional states can create instant connection and trust with others.• Create a personal "red flag" checklist for relationships, training yourself to spot inconsistencies, deflections, and boundary-testing behaviors before they escalate into manipulative scenarios.• Develop state control skills that allow you to remain emotionally detached enough to objectively analyze interactions, preventing chemical and emotional hijacking by skilled psychological manipulators.• Commit to studying human psychology beyond surface-level interactions, understanding that predatory behavior exists on a spectrum and recognizing early warning signs requires continuous self-education and awareness.Episode Timeline:[00:26] How the echo technique can influence anyone easily[06:41] Spotting social predators before they take advantage[14:40] The truth about narcissists and their manipulation tactics[18:15] Detecting deception and spotting hidden lies fast[34:18] Why predators target certain people and how to stay safe[1:12:21] Key strategies to protect yourself from manipulators[1:12:54] Final insights and exclusive training opportunityTo learn more about Dr. David Snyder and everything about NLP, visit:Website: https://www.nlppower.com/YouTube: https://www.youtube.com/@DavidSnyderNLPInstagram: https://www.instagram.com/davidsnydernlp

Justin and Matt watched episode 7 of season 1 of Daredevil Born Again, starring Charlie Cox as Matt Murdock and Vincent D'Onofrio as Wilson Fisk, now airing on Disney Plus. Want to join the crew for a watchalong? ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://ko-fi.com/lgr_network⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠YOUR HOSTS FOR THIS EPISODE

Most AI safety conversations centre on alignment: ensuring AI systems share our values and goals. But despite progress, we're unlikely to know we've solved the problem before the arrival of human-level and superhuman systems in as little as three years.So some are developing a backup plan to safely deploy models we fear are actively scheming to harm us — so-called “AI control.” While this may sound mad, given the reluctance of AI companies to delay deploying anything they train, not developing such techniques is probably even crazier.Today's guest — Buck Shlegeris, CEO of Redwood Research — has spent the last few years developing control mechanisms, and for human-level systems they're more plausible than you might think. He argues that given companies' unwillingness to incur large costs for security, accepting the possibility of misalignment and designing robust safeguards might be one of our best remaining options.Links to learn more, highlights, video, and full transcript.As Buck puts it: "Five years ago I thought of misalignment risk from AIs as a really hard problem that you'd need some really galaxy-brained fundamental insights to resolve. Whereas now, to me the situation feels a lot more like we just really know a list of 40 things where, if you did them — none of which seem that hard — you'd probably be able to not have very much of your problem."Of course, even if Buck is right, we still need to do those 40 things — which he points out we're not on track for. And AI control agendas have their limitations: they aren't likely to work once AI systems are much more capable than humans, since greatly superhuman AIs can probably work around whatever limitations we impose.Still, AI control agendas seem to be gaining traction within AI safety. Buck and host Rob Wiblin discuss all of the above, plus:Why he's more worried about AI hacking its own data centre than escapingWhat to do about “chronic harm,” where AI systems subtly underperform or sabotage important work like alignment researchWhy he might want to use a model he thought could be conspiring against himWhy he would feel safer if he caught an AI attempting to escapeWhy many control techniques would be relatively inexpensiveHow to use an untrusted model to monitor another untrusted modelWhat the minimum viable intervention in a “lazy” AI company might look likeHow even small teams of safety-focused staff within AI labs could matterThe moral considerations around controlling potentially conscious AI systems, and whether it's justifiedChapters:Cold open |00:00:00|  Who's Buck Shlegeris? |00:01:27|  What's AI control? |00:01:51|  Why is AI control hot now? |00:05:39|  Detecting human vs AI spies |00:10:32|  Acute vs chronic AI betrayal |00:15:21|  How to catch AIs trying to escape |00:17:48|  The cheapest AI control techniques |00:32:48|  Can we get untrusted models to do trusted work? |00:38:58|  If we catch a model escaping... will we do anything? |00:50:15|  Getting AI models to think they've already escaped |00:52:51|  Will they be able to tell it's a setup? |00:58:11|  Will AI companies do any of this stuff? |01:00:11|  Can we just give AIs fewer permissions? |01:06:14|  Can we stop human spies the same way? |01:09:58|  The pitch to AI companies to do this |01:15:04|  Will AIs get superhuman so fast that this is all useless? |01:17:18|  Risks from AI deliberately doing a bad job |01:18:37|  Is alignment still useful? |01:24:49|  Current alignment methods don't detect scheming |01:29:12|  How to tell if AI control will work |01:31:40|  How can listeners contribute? |01:35:53|  Is 'controlling' AIs kind of a dick move? |01:37:13|  Could 10 safety-focused people in an AGI company do anything useful? |01:42:27|  Benefits of working outside frontier AI companies |01:47:48|  Why Redwood Research does what it does |01:51:34|  What other safety-related research looks best to Buck? |01:58:56|  If an AI escapes, is it likely to be able to beat humanity from there? |01:59:48|  Will misaligned models have to go rogue ASAP, before they're ready? |02:07:04|  Is research on human scheming relevant to AI? |02:08:03|This episode was originally recorded on February 21, 2025.Video: Simon Monsour and Luke MonsourAudio engineering: Ben Cordell, Milo McGuire, and Dominic ArmstrongTranscriptions and web: Katy Moore

Are you confused about everything you're hearing about menopause? You hear one thing from me, then another from someone else and just not sure what to do? Do you just want to know the truth and challenge outdated beliefs so you can start taking some kind of action to feel better today, right now? Then this episode with my menopause besties and hormone experts Karen Martel and Dr. Fiona Lovely is for you. You get to be a fly on the wall of this fun roundtable discussion. We cover: The kind of menopause misinformation you're hearing and how to filter it Why misinformation still persists despite the growing awareness How different cultures across the globe experience and treat menopause The real implications behind hot flashes Why you may need to see a menopause specialist for your joint pain, not a traumatologist How your birth control may have affected your joints and brain health Bioidentical hormone therapy as a game changer How to advocate for yourself to get better care Karen Martel has a brilliant podcast called The Hormone Solution. She is a Certified Hormone Specialist and Transformational Nutrition Coach and has been working with women in this space with her online community and one to one for probably nearly a decade by now. In her podcast Karen tackles the complexities of hormonal health and really focuses on women with weight loss resistance. She always gives practical solutions and reliable information. Fiona has one of the longest running menopause podcasts with over a million downloads now - Not Your Mother's Menopause.. She is a women's health expert with specialties in functional medicine, functional neurology and restorative endocrinology.and takes a holistic approach to healing, focusing on finding the root cause of a woman's issues, reaching all aspects of health and making space for wellness. Contact Karen Martel: Website: https://karenmartel.com Podcast: https://karenmartel.com/blogs/podcast Facebook: https://www.facebook.com/karenmartelhormones Instagram: https://www.instagram.com/karenmartelhormones/ YouTube: https://www.youtube.com/channel/UCfWWN_4IhMZJOXjvj8FDKIQ Group coaching: https://coaching.karenmartel.com/ - code ZORA50 for 50% off   Hormone Creams: https://karenmartel.com/collections/all-products code ZORA for 10% off   Contact Dr. Fiona Lovely: Website: https://drlovely.com/ Instagram: https://www.instagram.com/drfionalovely TikTok: https://www.tiktok.com/@drfionalovely Podcast: Not Your Mother's Menopause: https://drlovely.com/#!/podcast   Give thanks to our sponsors: Qualia senolytics and brain supplements. 15% off with code ZORA here. Try BEAM minerals at 20% off with code ZORA here.http://beamminerals.com/ZORA Get Primeadine spermidine by Oxford Healthspan. 15% discount with code ZORA ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Get Mitopure Urolithin A by Timeline. 10% discount with code ZORA at https://timeline.com/zora Get Magnesium Breakthrough by Bioptimizers. 10% discount with code HACKMYAGE at https://bioptimizers.com/hackmyage Try OneSkin skincare with code ZORA for 15% off https://shareasale.com/r.cfm?b=2685556&u=4476154&m=102446&urllink=&afftrack= Join ⁠⁠⁠Biohacking Menopause⁠⁠⁠ before May 1, 2025 to win a bottle of Acceleradine iodine! 10% off with code ZORA at Acclerated Health.   Join the Hack My Age community on: Facebook Page: ⁠⁠⁠⁠⁠@⁠Hack My Age⁠ Facebook Group: ⁠⁠⁠⁠⁠⁠@⁠Biohacking Menopause⁠⁠⁠⁠⁠⁠ ⁠  Private Women's Only Support Group: https://hackmyage.com/biohacking-menopause-membership/ Instagram: ⁠⁠⁠⁠⁠@⁠HackMyAge⁠    Website: ⁠⁠⁠⁠⁠⁠HackMyAge.com⁠   

A company that uses hundreds of drones to inspect the power lines and wooden poles that criss-cross the countryside and forests, contributes to our protection against bushfires in Australia, because when there is a strong wind, there are sometimes short circuits and sparks and everything is quickly ablaze. Behind this company, which is paying attention, is a smart German from Bonn. - Zu unserem Schutz vor Buschbränden in Australien trägt eine Firma bei, die mit Hunderten von Drohnen die Stromleitungen und Holzmasten inspiziert, die Landschaft und Wälder durchziehen, denn bei starkem Wind kommt es manchmal zu Kurzschlüssen und Funken und schnell steht alles in Flammen. Hinter dieser Firma, die da aufpasst, steht ein smarter Deutscher aus Bonn.

40-40: 40 Years of Career Life Advice in 40 Minutes by Michael Allen Bell40-40: 40 Years of Career Life Advice in 40 Minutes is over 40 years of succinct insights and career advice packed into one small quick-read book. Short but meaningful tips and explanations on:•Project dynamics•Persuasion•Consensus•Conflict•Patterns to achieve success•Detecting false reasoning•Mistakes to avoid•Meeting leadership expectations•Overcoming challenges•Words of encouragement•Wisdom for the long haul•Constructive thinking leading to positive outcomes…And much more! This book will help you make good and do good.Michael Allen Bell is a cybersecurity risk advisor, application developer, and computer science instructor with over forty years of professional and academic experience. Among his specialties are knowledge engineering for harnessing human intelligence for decision making software assist to aid expert analysts. He has a bachelor's in mathematics and a master's in computer science, where he specialized in software project effort estimation. In off hours he delights in family time, and is an avid history and meteorology buff. AMAZONhttps://www.beta4helps.com/http://www.KingPagesPress.com   http://www.bluefunkbroadcasting.com/root/twia/4325kpp2.mp3    

There's a new app called Tea that promises to help women identify red flags before a first date. What is the #1 red flag you'd want a heads up on?

Trauma and paediatrics are the themes for this month's collection of papers. Starting off is a review of the effectiveness of prehospital ultrasound in detecting lung injury, with some surprising statistics. Next is a letter on the topic of self-presentation by paediatric patients with major trauma, which is thankfully a rare occurrence. The third paper looks at prehospital testing of trauma patients for  low fibrinogen levels, a condition which can lead to worse bleeding, increased transfusions, and higher mortality. The final paper discusses the worrying topic of delayed presentation with testicular pain, a phenomenon which leads to significantly lower salvage rates. This can arise from lack of information or embarrassment, particularly in younger males.   Read the highlights: April 2025 Primary Survey   Diagnostic accuracy of prehospital ultrasound in detecting lung injury in patients with trauma: a systematic review and meta-analysis Identifying the walk-in wounded: paediatric major trauma patients self-presenting to a paediatric major trauma centre Comparison between point-of-care international normalised ratio, COAST, TICCS and truncated FibAT scores to rule in clinically significant hypofibrinogenaemia in the prehospital setting Experiences and perceptions of acute testicular pain, with a focus on reasons for delayed presentation to hospital: a qualitative evidence synthesis   The EMJ podcast is hosted by: Dr. Richard Body, EMJ Deputy Editor, University of Manchester, UK (@richardbody) Dr. Sarah Edwards, EMJ Semior Associate Editor and Social Media Editor, Royal Derby Hospital, UK (@drsarahedwards) You can subscribe to the EMJ podcast on all podcast platforms to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the EMJ Podcast iTunes (https://apple.co/4bfcMU0) or Spotify (https://spoti.fi/3ufutSL) page.

Dr. Raphael Cuomo is a globally recognized biomedical scientist and professor at the UC San Diego School of Medicine, widely regarded as a foremost expert in cancer epidemiology, tobacco control, and health disparities. With a Ph.D. in Global Health from UC San Diego, he has produced notable research which has transformed our understanding of cancer outcomes in underserved populations, with a particular focus on tobacco-related cancers. As a principal investigator on multiple externally funded studies, Dr. Cuomo has developed innovative, data-driven models that integrate clinical informatics to optimize cancer care and improve public health interventions. His work has directly assessed national and global health policies, particularly in tobacco control and addressing health inequities, earning him recognition as a leading voice in the fight against cancer and tobacco-related diseases. With over 100 peer-reviewed publications and numerous prestigious awards, including election to the Delta Omega Honorary Society in Public Health, Dr. Cuomo's contributions to clinical research have set new standards in the field, cementing his legacy as a transformative figure in public health and clinical epidemiology. In this episode, Dr. Cuomo shares his insights on substances that increase cancer risk, which cancers are rising the fastest nowadays and much more. Learn more about Dr. Cuomo here: https://clre.ucsd.edu/faculty/raphael-cuomo/ CHAPTERS: 0:00 Intro 2:27 Stats on cancer 8:08 Cancers rising the fastest 12:30 Nutrition & cancer 20:35 Elimination diet 28:22 Breast cancer 32:00 Tobacco & cancer 37:55 Cannabis 39:37 Detecting cancer

Matters Microbial #84: Detecting Pathogens — and Worse — in Wastewater March 27, 2025 Today, Dr. Rachel Poretsky, Associate Professor of Biological Sciences at the University of Illinois Chicago joins the #QualityQuorum to discuss how examining wastewater (and related water) can give insights into the presence of pathogen antimicrobial resistance genes and even microbial ecology. Host: Mark O. Martin Guest: Rachel Poretsky Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A link to demonstrate the wonders of the Marine Biological Laboratories' Microbial Diversity course, which I know for a fact is life changing. Recommended by David Ranada, an article about water bottles and microbes.   An essay about the Chicago River and cholera, which led to the necessity of effective waste water treatment. An overview of the complexities of waste water treatment.  Here is a video on that topic.   An essay by Carl Zimmer about the microbial ecology of lakes…and human beings. How “recreational water quality” is determined. An article describing the microbiota associated with human biological waste with an amusing name (scroll down). How qPCR can be used to determine the prevalence of specific microbes. A recent article from Dr. Poretsky's research group, investigating how antimicrobial resistance genes can move through a hospital waste water system. A link to the Bacterial-Viral Bioinformatics Resource Center, for which Dr. Poretsky is a Principle Investigator. The Illinois state wastewater surveillance dashboard.  Fascinating! A Discovery Channel documentary on virus hunting and surveillance that includes Dr. Poretsky. Dr. Poretsky's faculty webpage. Dr. Poretsky's webpage for her research group. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

In this episode of the California Underground Podcast, hosts Phil and Camille discuss various topics related to California politics, including Rosie O'Donnell's recent comments on election denialism, the billion-dollar deficit facing Los Angeles, and Karen Bass's request for a bailout from Sacramento. They also delve into Gavin Newsom's satellite launch aimed at detecting methane emissions and the implications of a recent poll showing a significant percentage of California voters considering a Republican governor in the next election.Are you a Californian who feels isolated and alone in your political views in a deep blue state? Feel like you can't talk about insane taxes, an overbearing government, and radical social experiments without getting a side eye? Then join us on the California Underground Podcast to hear from people just like you. Original air date 3.25.25Chapters03:29 Rosie O'Donnell's Election Denialism06:18 Los Angeles' Billion Dollar Deficit09:36 Karen Bass and the Sacramento Bailout12:18 Gavin Newsom's Satellite Launch15:32 The Methane Detection Initiative18:24 Federal Funding and State Projects21:34 Conclusion and Final Thoughts41:34 The Coalition for Climate Action44:47 Success Stories in Climate Initiatives46:42 The Environmental Impact of Tracking Methane49:15 Understanding the EPA's Endangerment Finding52:47 Political Shifts in California57:41 The Growing Republican Presence in California01:01:48 Trends in California Politics01:06:10 The Future of California's Political Landscape*The California Underground Podcast is dedicated to discussing California politics from a place of sanity and rationality.*Check out our full site for more information about the show at www.californiaunderground.liveCheck out our sponsor for this episode, StopBox, by going to www.stopbox.com/californiaunderground to get 10% off your orderFollow California Underground on Social Media  Instagram: www.instagram.com/californiaunderground X: https://twitter.com/CAUndergoundTik Tok: https://www.tiktok.com/@californiaunderground?_t=8o6HWHcJ1CM&_r=1YouTube: https://www.youtube.com/channel/UCj8SabIcF4AKqEVFsLmo1jA Read about our Privacy Policy: https://www.spotify.com/us/legal/privacy-policy/ 

He has led the firm's business development efforts in a competitive Latin America territory providing global health group policies, group life insurance, special risk policies, pension plans for ex-pats, and other benefits.He is a Global Leader Risk Advisor and Entrepreneur who also speaks Spanish, and Portuguese.He is a professional in his field of discipline on how he would design a protocol to follow in case of a crisis in an event you or a CEO of a company gets kidnapped for ransom. He can provide advisement on what places in Spain he would recommend visiting while traveling there. Also, he gives recommendations to those contemplating traveling to Mexico for the Holidays.Currently manages a team of six (6) high-performance agents throughout Latin America. Has successfully recovered an art piece of a client that was stolen by a former associate of the owner.Delivers advisement on how to mitigate complex situations and manage solutions pertaining to health, as well as art and other collectibles (e.g., personal, corporate, museums, galleries).He is the Director and Owner of Uriegas Global Risk Advisors, Houston, TX. https://www.linkedin.com/in/uriegashttp://www.yourlotandparcel.org

Because there are no symptoms in the early stages of pancreatic cancer “about 75 to 80 percent of patients are diagnosed in the later stages of the disease,” said Somashekar Krishna, MD, a James physician scientist who specializes in the early detection and screening of pancreatic cancer. Krishna and the team of pancreatic cancer experts at the James are using enhanced screening and artificial intelligence (AI) to better identify pre-cancerous cysts and cancerous tumors in the pancreas; and are the first in the world to use high-tech ablation techniques to attack and kill pancreatic cysts and tumors in a new clinical trial. Most pancreatic cancer tumors begin as pre-cancerous cysts and are most commonly found in people 60 and older. “For people in their 50s there is about a 10-percent prevalence, this doubles in people 60 to 70 to 20 percent and is 25 to 30 percent in people 70 to 80,” Krishna said, adding, “most are small and never grow and become cancerous.” Endoscopy procedures are used to better “see” these cysts and cancerous tumors, and the use of artificial intelligence is another tool to identify and determine the risk factor of pre-cancerous cysts. “The tip of the endoscopy probe can see even the tiniest structures in a very detailed manner, and we can pass a needle through the scope and do a biopsy and establish the risk,” Krishna said. Surgery is one option, but the procedure is quite invasive and not easily tolerated by older patient with other medical issues. “A new option is ablation, using heat, in a very precise and careful manner,” Krishna said. “We are the only ones doing this in the United States and have done this with nearly 30 patients in a clinical trial.” Krishna is determined to improve screening and treatment for pancreatic cancer and reduce the mortality rate. “Early in my career, 80 percent of patients diagnosed with pancreatic cancer did not make it more than a year,” he said. “We want to change these outcomes to intervene early and with better and better treatment options.”

In this groundbreaking episode of Fusionary Health, Dr. Shivani Gupta sits down with Andrew Lacy, founder of Prenuvo, to explore how whole-body MRI technology is revolutionizing preventive healthcare. Discover the inspiring story of how a detailed car inspection report became the catalyst for creating a screening technology that detects cancers at their earliest, most treatable stages. Dr. Gupta shares her personal experience with the scan, which detected early warning signs that could have significant implications for her long-term brain health. Key Highlights: •        How Prenuvo detects early-stage cancers including pancreatic and ovarian cancer •        Why traditional imaging centers prioritize throughput over quality •        The spa-like experience designed to reduce medical anxiety •        New "Enhance" scan featuring body composition analysis, advanced neurological examination, and blood testing •        How Prenuvo's approach aligns with Eastern medicine's systemic view of the body •        International expansion to Melbourne and London Why You Should Listen Imagine knowing exactly what's happening inside your body, catching potential issues years or even decades before symptoms appear. This conversation demonstrates how preventive scanning transforms cancer diagnoses from life-changing events to manageable outpatient procedures, and how early detection of various conditions can fundamentally alter your health trajectory. Dr. Gupta's personal experience with detecting early warning signs for potential cognitive issues shows how this technology empowers us to take proactive steps today that could prevent serious health problems tomorrow. Experience the future of healthcare by using code "DrShivani" for $300 off your own Prenuvo scan at pranuvo.com. Learn more about our host visit: www.shivanigupta.com Show sponsored by Fusionary Formulas. Visit www.fusionaryformulas.com use code FUSIONARYHEALTH for 15% off your entire order. #PreventiveHealth #WholeBodyMRI #CancerDetection #HealthcareInnovation #FusionaryHealth #EarlyDiagnosis #AndrewLacy #DrShivaniGupta

As we put more and more satellites in orbit, chances of them colliding also increase. How can we manage that? How can we make sure that Kessler syndrome won't happen and keep all those satellites from destroying each other? Finding out in this interview.

As we put more and more satellites in orbit, chances of them colliding also increase. How can we manage that? How can we make sure that Kessler syndrome won't happen and keep all those satellites from destroying each other? Finding out in this interview.

Our 203rd episode with a summary and discussion of last week's big AI news! Recorded on 03/14/2025 Hosted by Andrey Kurenkov and Jeremie Harris. Feel free to email us your questions and feedback at contact@lastweekinai.com and/or hello@gladstone.ai Read out our text newsletter and comment on the podcast at https://lastweekin.ai/. Join our Discord here! https://discord.gg/nTyezGSKwP In this episode: OpenAI's new 'deep research' feature has raised concerns about cybersecurity and the potential misuse of AI models for bio-weapons and autonomous capabilities, prompting new safety and governance measures. Google's extensive $3 billion investment in Anthropic is revealed, aligning with their AI strategy and reinforcing the importance of multiple technology partnerships. Huawei's advancements in the AI chip industry are highlighted, with significant progress in producing chips comparable to Nvidia's H100, despite export control challenges. China's recent directive discourages AI executives from traveling to the US, reflecting heightened security concerns and potentially signaling a more adversarial stance in the AI race. Timestamps + Links: (00:00:00) Intro / Banter (00:01:30) News Preview Tools & Apps (00:02:30) OpenAI launches new tools to help businesses build AI agents (00:08:50) You can now test Gemini 2.0 Flash's native image output  (00:13:32) Waymo is now offering 24/7 robotaxi rides in Silicon Valley (00:17:19) Moonvalley releases a video generator it claims was trained on licensed content (00:21:11) Snap introduces AI Video Lenses powered by its in-house generative model (00:23:37) Sudowrite Launches Muse AI Model That Can Generate Narrative-Driven Fiction Applications & Business (00:27:48) In another chess move with Microsoft, OpenAI is pouring $12B into CoreWeave (00:30:54) Huawei's Ascend 910C Takes on NVIDIA as China's AI Race Heats Up: More Alleged Details (00:36:26) Huawei reportedly acquired two million Ascend 910 AI chips from TSMC last year through shell companies (00:40:27) Inside Google's Investment in the A.I. Start-Up Anthropic (00:43:26) Meta is reportedly testing in-house chips for AI training (00:46:48) Elon Musk's xAI buys 1 million sq ft site for second Memphis data center (00:50:02) Superintelligence startup Reflection AI launches with $130M in funding Projects & Open Source (00:53:11) Google calls Gemma 3 the most powerful AI model you can run on one GPU (00:58:18) Sesame, the startup behind the viral virtual assistant Maya, releases its base AI model (01:01:13) Reka AI Open Sourced Reka Flash 3: A 21B General-Purpose Reasoning Model that was Trained from Scratch (01:04:19) Open-Sora 2.0: Training a Commercial-Level Video Generation Model in $200k Research & Advancements (01:06:25) Google's Gemini Robotics AI Model Reaches Into the Physical World (01:14:33) Optimizing Test-Time Compute via Meta Reinforcement Fine-Tuning (01:23:29) Deep Research System Card (01:29:50) Claude 3.7 Sonnet System Card Policy & Safety (01:33:24) Detecting misbehavior in frontier reasoning models (01:39:30) China tells its AI leaders to avoid US travel over security concerns, WSJ reports (01:43:48) Outro

It's been about a month since Donald Trump was sworn into office and they've already begun stripping the country of copper wiring, slashing a multitude of government agencies and attempting to facilitate large scale deregulation. This has led to some pretty absurd mistakes by the administration. Like when they fired a sizable chunk of the department of energy, only to attempt to scramble to rehire a group of nuclear safety workers only to realize that they didn't actually have these worker's contact information, as they no longer had access to their government email accounts. It appears that no one is at the wheel right now. You are being run by a kakistocracy, or rule by the worst, although given that the vice president and reddit billionaire shadow president both clearly have browsed 4chan too much, it seems more like a “kekistocracy” at the moment. Liv, Travis, and Jake discuss the lies that are flying out of DOGE and Elon Musk, the consequences of massive regulatory capture, the Trump admin's plans to declassify old documents, and what r/conspiracy thinks about the new, "uncensored" version of ChatGPT. Subscribe for $5 a month to get all the premium episodes: https://patreon.com/qaa SOURCES: Trump froze a bribery law that previously hit suppliers for Elon Musk's Tesla https://www.cnbc.com/2025/02/12/trump-foreign-bribery-law-elon-musk-tesla-minerals.html SSA OIG: Preventing, Detecting, and Recovering Improper Payments https://oig.ssa.gov/assets/uploads/072401.pdf No, 150 Year Olds Aren't Collecting Social Security Benefits https://www.wired.com/story/elon-musk-doge-social-security-150-year-old-benefits/ How Trump's Firings “Paralyze” the NLRB https://www.motherjones.com/politics/2025/02/trump-nlrb-firing-musk-doge-workers-rights-labor-unions-paralyze/ Elon Musk's DOGE takes aim at agency that had plans of regulating X https://www.npr.org/2025/02/12/nx-s1-5293382/x-elon-musk-doge-cfpb DOGE Claimed It Saved $8 Billion in One Contract. It Was Actually $8 Million. https://archive.is/tmWZl#selection-4583.0-4586.0 Open AI Tries To “Uncesor” ChatGPT https://techcrunch.com/2025/02/16/openai-tries-to-uncensor-chatgpt/ FBI says it has discovered new files on JFK assassination https://www.cnn.com/2025/02/11/politics/jfk-assassination-files/index.html Scoop: FBI finds secret JFK assassination records after Trump order https://www.axios.com/2025/02/10/trump-jfk-assassination-records

America aims to avoid nuclear war by relying on the principle of 'mutually assured destruction,' right? Wrong. Or at least... not officially.As today's guest — Jeffrey Lewis, founder of Arms Control Wonk and professor at the Middlebury Institute of International Studies — explains, in its official 'OPLANs' (military operation plans), the US is committed to 'dominating' in a nuclear war with Russia. How would they do that? "That is redacted."Rebroadcast: this episode was originally released in December 2022.Links to learn more, highlights, and full transcript.We invited Jeffrey to come on the show to lay out what we and our listeners are most likely to be misunderstanding about nuclear weapons, the nuclear posture of major powers, and his field as a whole, and he did not disappoint.As Jeffrey tells it, 'mutually assured destruction' was a slur used to criticise those who wanted to limit the 1960s arms buildup, and was never accepted as a matter of policy in any US administration. But isn't it still the de facto reality? Yes and no.Jeffrey is a specialist on the nuts and bolts of bureaucratic and military decision-making in real-life situations. He suspects that at the start of their term presidents get a briefing about the US' plan to prevail in a nuclear war and conclude that "it's freaking madness." They say to themselves that whatever these silly plans may say, they know a nuclear war cannot be won, so they just won't use the weapons.But Jeffrey thinks that's a big mistake. Yes, in a calm moment presidents can resist pressure from advisors and generals. But that idea of ‘winning' a nuclear war is in all the plans. Staff have been hired because they believe in those plans. It's what the generals and admirals have all prepared for.What matters is the 'not calm moment': the 3AM phone call to tell the president that ICBMs might hit the US in eight minutes — the same week Russia invades a neighbour or China invades Taiwan. Is it a false alarm? Should they retaliate before their land-based missile silos are hit? There's only minutes to decide.Jeffrey points out that in emergencies, presidents have repeatedly found themselves railroaded into actions they didn't want to take because of how information and options were processed and presented to them. In the heat of the moment, it's natural to reach for the plan you've prepared — however mad it might sound.In this spicy conversation, Jeffrey fields the most burning questions from Rob and the audience, in the process explaining:Why inter-service rivalry is one of the biggest constraints on US nuclear policyTwo times the US sabotaged nuclear nonproliferation among great powersHow his field uses jargon to exclude outsidersHow the US could prevent the revival of mass nuclear testing by the great powersWhy nuclear deterrence relies on the possibility that something might go wrongWhether 'salami tactics' render nuclear weapons ineffectiveThe time the Navy and Air Force switched views on how to wage a nuclear war, just when it would allow *them* to have the most missilesThe problems that arise when you won't talk to people you think are evilWhy missile defences are politically popular despite being strategically foolishHow open source intelligence can prevent arms racesAnd much more.Chapters:Cold open (00:00:00)Rob's intro (00:01:05)The interview begins (00:03:31)Misconceptions in the effective altruism community (00:06:24)Nuclear deterrence (00:18:18)Dishonest rituals (00:28:59)Downsides of generalist research (00:32:55)“Mutual assured destruction” (00:39:00)Budgetary considerations for competing parts of the US military (00:52:35)Where the effective altruism community can potentially add the most value (01:02:57)Gatekeeping (01:12:46)Strengths of the nuclear security community (01:16:57)Disarmament (01:27:40)Nuclear winter (01:39:36)Attacks against US allies (01:42:28)Most likely weapons to get used (01:45:53)The role of moral arguments (01:47:22)Salami tactics (01:52:43)Jeffrey's disagreements with Thomas Schelling (01:57:42)Why did it take so long to get nuclear arms agreements? (02:01:54)Detecting secret nuclear facilities (02:04:01)Where Jeffrey would give $10M in grants (02:06:28)The importance of archival research (02:11:45)Jeffrey's policy ideas (02:20:45)What should the US do regarding China? (02:27:52)What should the US do regarding Russia? (02:32:24)What should the US do regarding Taiwan? (02:36:09)Advice for people interested in working on nuclear security (02:38:06)Rob's outro (02:39:45)Producer: Keiran HarrisAudio mastering: Ben CordellTranscriptions: Katy Moore

John Petrocelli reveals the science behind detecting BS, which has become so pervasive in today's world. What is the difference between lying and bullshitting? What makes BS more dangerous than lying? How do we develop the critical thinking habits needed to detect it? Find this out and much more. Subscribe for ad-free interviews and bonus episodes https://plus.acast.com/s/the-unmistakable-creative-podcast. Hosted on Acast. See acast.com/privacy for more information.

Imagine detecting cancer with just a single drop of blood. In this episode of the Beautifully Broken Podcast, host Freddie Kimmel engages in a compelling conversation with Dr. Joshua Routh, MD, a distinguished expert in pathology and molecular oncology. Dr. Routh serves as the Laboratory Director for high-complexity clinical laboratories and holds the position of Associate Professor of Pathology at Midwestern University. He is also the Medical Director for Precision Epigenomics Inc., where he focuses on multi-cancer early detection tests.Together, they examine the science behind EPISEEK, discussing how it analyzes epigenetic markers in the blood to identify potential cancer signals. The conversation covers the importance of methylation in gene expression, the emotional implications of cancer testing, and who should consider getting tested. Dr. Routh emphasizes the need for patient autonomy and informed decision-making in the context of cancer screening. They also explore the advancements in multi-cancer early detection tests, focusing on the technology behind EPISEEK, its cost, and the current lack of insurance coverage. The discussion touches on the implications of abnormal test results, the importance of patient-doctor collaboration, and the need for a holistic approach to health that includes lifestyle factors. Additionally, they discuss the strengths and limitations of current cancer detection technologies and the importance of comprehensive health monitoring.Highlights1:32 Introduction: Personal Reflections on the Importance of Early Cancer Detection3:05 Understanding EpiSeek: A Breakthrough in Liquid Biopsy Technology for Cancer Detection5:40 The Science of EpiSeek: How It Works to Detect Cancer Early8:14 The Role of Methylation in Gene Expression and Its Link to Cancer Growth10:42 Gene Expression and Epigenetics: Why They Matter in Cancer Screening13:20 Interpreting Test Results: What to Do After Receiving an Abnormal Finding16:35 Who Should Get Tested? Assessing Risk Factors, Family History, and Lifestyle19:48 The Emotional Impact of Cancer Screening and the Decision Not to Test22:14 Comparing EpiSeq to Other Multi-Cancer Early Detection Tests25:52 Insurance Coverage for Multi-Cancer Tests: Current Challenges and Future Prospects29:30 Next Steps After an Abnormal Test Result: Further Screening and Actions33:40 The War on Cancer: How Lifestyle Choices Influence Cancer Risk36:15 - Evaluating the Strengths and Limitations of Current Cancer Detection Technologies40:28 - The Importance of Comprehensive Health Monitoring Beyond Single TestsUPGRADE YOUR WELLNESSEpiSeq Test: https://www.precision-epigenomics.com/episeqExclusive $50 Discount Offer (Valid Until August 1, 2025): https://www.precision-epigenomics.com/offerSilver Biotics Muscle Cream: https://www.silverbiotics.com (Use Code: BEAUTIFULLYBROKEN for Discount)Saga Bands: https://ca.saga.fitness/?ref=titvyccmCode: beautifullybrokenStemRegen: https://www.stemregen.co/products/stemregen?_ef_transaction_id=&oid=1&affid=52Code: beautifullybrokenLightPathLED https://lightpathled.pxf.io/c/3438432/2059835/25794Code: beautifullybroken CONNECT WITH FREDDIE Check out my website and store: (http://www.beautifullybroken.world) Instagram: (https://www.instagram.com/beautifullybroken.world/) YouTube: (https://www.youtube.com/@BeautifullyBrokenWorld)