Podcasts about detecting

AI cyberattacks are forcing businesses to rethink cybersecurity as criminals increasingly use the same powerful technology available to defenders. Morné Laubscher, Chief Technology Officer at Logicalis, and Nabeel Rajab, Cisco Security Solutions Manager, explain how artificial intelligence is reshaping the cybersecurity battle for South African organisations. They discuss why traditional security approaches are struggling against AI-powered threats, particularly as businesses accumulate multiple disconnected security tools and huge volumes of data. Rajab walks through how a modern ransomware attack can move from a malicious link to compromised devices, networks, and critical company data without immediately being detected. The conversation also explores how AI can connect security signals and automate responses at machine speed. Laubscher explains why identity has become a major security frontier, while Rajab outlines the importance of zero trust and operating on the assumption that a breach could already have occurred. They also discuss managed cybersecurity services and how businesses without large internal security teams can access specialist skills and technology. 0:00 Intro 1:41 How serious is the cyber threat? 4:01 Why traditional cybersecurity is failing 5:16 Fighting AI attacks with AI 8:13 Identity and zero-trust security 9:42 How a ransomware attack works 15:05 Detecting and stopping attacks with AI 20:29 What businesses should do now Follow MyBroadband: X - https://twitter.com/mybroadband Facebook - https://www.facebook.com/mybroadband Instagram - https://www.instagram.com/mybroadband/ Website - https://mybroadband.co.za/news/ #Cybersecurity #ArtificialIntelligence #Ransomware

Stories:* ⭐ An INCREDIBLE Investigative Piece EXPOSING the Hasbara Network Players & Orgs* ⭐ West Bank Escalation, Props for Assal Rad, Driving as a Palestinian Woman, “Board of Peace” Silence* ⭐ Whitney Webb's Warning About Pangram, the AI Detector* ⭐ Colorado River Crisis, Kostakidis Suit DROPPED, New Truthstream Video, Substack Analytics QuestionsFor the links to all the articles & videos shown on the show plus the links to watch/share on every other platform, click here: https://www.indiemediatoday.com/p/indie-news-now-live-links-09-15-26?r=539iuHelp fund the media you want to see! Indie Media Today and Indie News Network operate on a “Value for Value system.” Everything we do is free to all. We don't paywall our content, but we do need - and deeply appreciate - your support in order to keep running. One way to do that is with a monthly or annual subscription here.A $5/mo subscription here or on Ko-Fi.com helps us continue to produce quality content that challenges mainstream corporate funded narratives & amplify independent voices.Please support your favorite Indie Media creators! IndieNewsNow LIVE! covers stories corporate media doesn't want to tell, and from an angle they would NEVER tell it. Each episode, we showcase the work of dedicated independent reporters, researchers, and grassroots news outlets who are digging deeper on issues that matter, free from advertiser and corporate influence. Break free from the media focused on the duopoly and discover the news you're not supposed to see.Perfect for viewers who:* Are skeptical of corporate-controlled news narratives* Want to be more deeply informed on critical issues* Believe in supporting independent journalism* Feel like there's always more to the storySubscribe to IndieNews Network (INN) and hit the bell

Podcasting 2.0 September 11th 2026 Episode 270 - "YOLO Guy Dave waves the whitflag on agentic coding and podcasting beneifts! 01 -

It turns out not all heroes wear capes, some wear lab coats! In an age where facts seem debatable and the truth can be so easily manipulated, one woman is on a mission to root out mistakes, fraud, and cheats in the scientific world. Dutch microbiologist and scientific integrity consultant Dr Elisabeth Bik is famous for scanning biomedical literature to detect image duplication and research fraud. She spoke to Emile from her home in Amsterdam.

When sports people are assessed for concussion, doctors look for physical signs and consider the results of brain function tests. Researchers at The University of Queensland are developing a new approach based on small magnetic fields produced by neurons. The idea is to compare the magnetic fields before and after a suspected head knock. Any changes would reveal whether concussion has occurred and its severity.

“Does DNA barcoding actually work?” It's the first question Kent Rapp hears from prospective customers when he pitches Biolinco's DNA barcoding platform. By his own admission, the technology can sound too good to be true.In Part 2 of this conversation, Kent rejoins the Smart Biotech Scientist Podcast to address that skepticism head-on, unpack how subclone variability and bispecific antibody purity concerns shape customer trust, and share what it actually took to move Biolinco from a Johns Hopkins postdoc project to a company with its first paying customer.In this episode:Common pushbacks and questions from industry regarding new cell line development technologies (03:18)Practical advice for resource-constrained startups developing cell lines, emphasizing efficiency and data quality over brute force automation (08:42)The role and value of DNA barcoding in screening and developing robust cell lines for therapeutics (08:56)Lessons learned from translating scientific innovation into a commercial product, including securing early support and customer trust (10:27)Insights on adapting messaging, leveraging feedback, and understanding market needs as part of the entrepreneurial process (13:52)Key differences between academic research and industry requirements for reliable, repeatable biotech tools (15:26)Kent's most important takeaway for successful cell line development: focus on collecting the right data at the right scale for informed decisions (17:14)Smart insight: Translating innovations from academia to industry brings a new wave of challenges. Kent describes the “valley of death” separating a publishable prototype from a reliable, commercial-grade product. Academic success is often tied to novelty, publications, and grants, while industry demands repeatability, robustness, and consistent performance across labs and operators. Securing early champions and funding, iterating based on tough industry feedback, and building trust with initial partners all require resilience, and a willingness to pivot as needed. Feedback, even when harsh, becomes a “gift” that helps refine the product and business model. The secret is not a single breakthrough, but adaptability and relentless customer focus.If this got you rethinking how you screen clones, you'll want these next. We've tackled cell line development, high-throughput screening, and the art of spotting manufacturable candidates early from a few different directions — here are four worth queuing up.Episodes 117 - 118 : Cell Line Development Secrets: Eliminating Critical Bottlenecks for Faster Timelines with Andrea GoughEpisodes 09 - 10: Revolutionizing Cell-Line Development: Unleashing the Power of Nanopens and Microenvironments with Tanner NevillEpisodes 123 - 124: Manufacturability: Why Most Protein Candidates Fail (And How to Pick Winners Early) with Susan SharfsteinEpisodes 115 - 116: Revolutionizing Biologics Development with Hyper Throughput Screening and AI with Jeremy AgrestiConnect with Kent Rapp:LinkedIn: www.linkedin.com/in/kent-rapp Biolinco website: www.biolinco.comFree 5-day email course, The CMC Failure Chain: the five recurring CMC mistakes that put your promising program at risk → Get it hereSupport the show

On this episode of Diabetes Connections In the news… The FDA approves a new indication and health benefit for Mounjaro, lots of CGM news including an update on Medicare coverage for people who don't use insulin and a new study about using CGM when you don't have diabetes, metformin and aging, statins and type 2, and did you know there was a Dolly Parton diabetes connections? That and much more... Check out all of our events like Moms' Night Out and Club 1921 here. Announcing Community Commericals! Learn how to get your message on the show here. Learn more about studies and research at Thrivable here Please visit our Sponsors & Partners - they help make the show possible! Omnipod - Simplify Life All about Dexcom  All about VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com  On this episode of Diabetes Connections In the news… The FDA approves a new indication and health benefit for Mounjaro, lots of CGM news including an update on Medicare coverage for people who don't use insulin and a new study about using CGM when you don't have diabetes, metformin and aging, statins and type 2, and did you know there was a Dolly Parton diabetes connections? That and much more.. that's coming up right after this. (AD BREAK) Welcome! I'm your host Stacey Simms and this is an In The News episode.. where we bring you the top diabetes stories and headlines happening now. A reminder that you can find the sources and links and a transcript and more info for every story mentioned here in the show notes. Welcome to September! Want to let you know about a webinar I'm doing with Abbott later this month. That's Sept 23 at 7pm ET. We'll be talking about ketones, DKA and learn more about their dual CGM/ketone monitor that was just approved – more on that coming up. But please register – the link is in the show notes. So much going on over here – tomorrow night we have our Club 1921 in Charlotte, later this month Moms' Night Out Detroit/Bloomfield and in October we're going to Seattle. Please join us. More at d-c dot com slash events. Okay.. our top story this week: XX Another indication for Mounjaro – the FDA approved it to lower the risk of major adverse cardiovascular (CV) events (MACE), including CV death, non-fatal heart attack, or non-fatal stroke in adults with type 2 diabetes who are at high risk for these events. Mounjaro – the brand name of tirzepatide - is already approved as an adjunct to diet and exercise to improve blood sugar in adults and children 10 years of age and older with type 2 diabetes. The approval was based on results from the largest and longest tirzepatide study to date, enrolling more than 13,000 participants across 30 countries over more than four and a half years. In the trial, Mounjaro demonstrated non-inferiority to Trulicity (dulaglutide), a GLP-1 treatment with established cardiovascular benefit, with an 8% lower rate of cardiovascular death, heart attack or stroke (MACE-3). The estimated hazard ratio for time to first MACE was 0.92 (95.3% CI: 0.83, 1.01) for Mounjaro compared to Trulicity (dulaglutide). https://www.prnewswire.com/news-releases/fda-approves-lillys-mounjaro-tirzepatide-to-reduce-cardiovascular-risk-in-adults-with-type-2-diabetes-302862415.html XX The FDA approves the Libre Duo – the first device designed to continuously monitor both blood sugar levels and ketone levels in people with diabetes. The Libre Duo 10-Day Continuous Dual Glucose Ketone Monitoring System is now approved for those ages 2 and older. Until now, the agency said, people had to monitor ketone levels with separate tests that only provided a single measurement at one point in time. The new system combines blood sugar and ketone tests and monitors them continuously. Readings -- and alerts in case of dangerous trends -- are sent wirelessly to a smartphone app. The FDA previously granted "breakthrough device" status to the system, which is meant to expedite the device's development and review. https://www.upi.com/Top_News/US/2026/08/25/fda-oks-blood-sugar-ketone-monitor/5521787688375/ XX Diabetes tech firms Dexcom and Abbott are watching closely for a Medicare coverage expansion that could significantly broaden access to their glucose sensors. The Centers for Medicare and Medicaid Services is expected to expand Medicare coverage of continuous glucose monitors to people with diabetes who do not take insulin. Currently, coverage is limited to people with Type 1 or Type 2 diabetes who take insulin or have a history of problematic low blood sugar. Dexcom CEO Jake Leach told investors in a late July earnings call that the company expects to hear back from the CMS before the end of the year, with coverage going into effect in mid-2027.     Dexcom presented results of a randomized, controlled trial earlier this summer at the American Diabetes Association's Scientific Sessions that it expects will support the CMS' decision. The 26-week study found that people who used a CGM had a larger hemoglobin A1C reduction than the control group and spent five more hours per day in a normal glucose range than the control group. https://www.medtechdive.com/news/dexcom-abbott-await-medicare-coverage-expansion-for-cgms/828775/ XX A new study suggests continuous glucose monitors (CGMs) may offer benefits for people with type 1 diabetes that go beyond improving blood sugar and reducing hypoglycemia.   Researchers analyzed health records from more than 8,400 adults with type 1 diabetes receiving care through the Veterans Health Administration. Over one to four years of follow-up, people who started using a CGM had a 10% to 16% lower risk of death from any cause compared with those who did not use one.   The association appeared strongest among people over age 65 and those who were not using insulin pumps. Researchers did not find meaningful differences based on A1C, race or ethnicity, or frailty.   Importantly, this was an observational study using medical records, not a randomized clinical trial, so it cannot prove that CGM use directly caused the lower death rate. But the findings suggest CGM may have important long-term health benefits beyond glucose management.https://visualize.jove.com/42319755-continuous-glucose-monitoring-initiation-is-associated-with-reduced-mortality-in-older-onset-type-1-diabetes-patients-a-target-trial-emulation-study-within-the-veterans-health-administration XX We've been talking about people without diabetes using CGMs for a long time.. now a new study weighs in. Research published in JAMA finds that this wellness trend isn't helpful for people without a diabetes diagnosis. They found that the strongest evidence for CGM use is for people who are already living with diabetes, but not for those without the condition who use them for wellness purposes. It's also worth noting, though, that this new study is a narrative review. This means that the researchers drew their conclusions from the findings reported in several other studies. More randomized controlled trials would be necessary to see whether there are any meaningful health benefits of using a CGM if you don't have diabetes.   Dower also warned that constantly monitoring your blood sugar when you don't have diabetes could lead to unintended health anxiety. In some cases, you may even make accidental lifestyle changes that could be harmful. "[Blood sugar] spikes may occur after meals, but if this leads someone to replace healthy food such as fruit with unhealthy food such as something high in fat but low in carbohydrate, the glucose information has done more harm than good," Dower said. https://www.verywellhealth.com/blood-sugar-monitor-for-people-without-diabetes-12058575   XX   Could metformin somehow influence the biological processes that drive aging? A new review found evidence that metformin may affect several key features of aging, including how cells use energy, inflammation, cellular damage and even some changes in gene activity. Animal studies have shown longer lifespans or improvements in markers of biological aging, while some human studies have also found promising results.   But researchers say there's still no proof that metformin actually slows aging or helps healthy people live longer. Most human research has involved people with diabetes or other health conditions, and one large trial found that while metformin helped prevent type 2 diabetes, it did not reduce cancer, cardiovascular disease or deaths.   Researchers say larger clinical trials in people without diabetes are needed to determine whether metformin can truly extend healthy lifespan—or whether its benefits are primarily related to preventing and treating specific diseases. https://www.technologynetworks.com/drug-discovery/news/metformin-may-influence-longevity-through-the-gut-microbiome-and-epigenetic-changes-416035 XX More to come including more research on a spice thought to help diabetes, predictions about the number of people who may be living with type 1 in the years to come around the world, and a connection I didn't know about between diabetes and Dolly Parton.   XX A compound found in turmeric may help protect blood vessels from some of the damage caused by Type 1 diabetes. In rats, curcumin reduced inflammation, improved cellular signaling, and restored vascular health to levels resembling those of nondiabetic animals. The results hint at a possible new way to reduce the long-term cardiovascular risks of diabetes, but human trials are still needed. Curcumin, the natural compound responsible for turmeric's vivid yellow color, is widely studied for its anti-inflammatory and antioxidant properties. https://www.sciencedaily.com/releases/2026/08/260824065543.htm XX New research estimates the number of people living with type 1 diabetes (T1D) worldwide will increase by 29% from 9.4 million in 2025 to 12.1 million in 2049. This will be presented at EASD, the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2 The USA will see an increase of over half a million, going from 1,492,825 to 2,055,235. The authors suggest that the reasons for the predicted high incidence and prevalence in 2049 in countries such as Australia, US, UK are likely to be a combination of genetics, environmental triggers and also high case detection rates (due to the good health care infrastructure here and in other HIC). Unlike previous estimates, the DIAMOND-T1D model takes historical patterns of insulin availability into account and aims to provide global, regional and country-specific estimates of T1D incidence, prevalence and mortality from 1900 to 2050. Although the majority of people with T1D live in high-income countries (HIC) and middle-income countries (MIC), the largest relative increase in the T1D prevalence is expected to occur in LIC as access to insulin, glucose monitoring and survival all improve in those countries. https://www.news-medical.net/news/20260828/Type-1-diabetes-cases-projected-to-increase-worldwide-by-2049.aspx XX Early initiation of statins after a diagnosis of type 2 diabetes was associated with a lower risk of dementia, according to a study published in The Lancet Regional Health – Europe. According to the Lancet Commission, nearly half of dementia cases could theoretically be prevented by eliminating 14 risk factors. "Detecting and treating high levels of low-density lipoprotein cholesterol (LDL-C) from midlife is one such highlighted risk factor," From Danish registers, researchers identified 132,585 statin-naive individuals who developed type 2 diabetes from 2006 through 2019, with follow-up until the end of 2021.   Medical records were searched for diagnoses of all-cause dementia. A clone-censor-weight design was used to analyze dementia incidence in patients with no statin initiation within five years after diagnosis, in those with early statin initiation within one year and in those with late statin initiation between one and five years after diagnosis.   https://medicalxpress.com/news/2026-08-early-statins-diagnosis-diabetes-dementia.html   XX We are heartbroken over the loss of our friend Dolly Parton. Dolly was a beloved icon whose extraordinary generosity, warmth, and compassion touched countless lives, including those of the Children's Diabetes Foundation and the Barbara Davis Center for Diabetes. Her support of The Carousel Ball and Carousel of Hope Ball reflected her deep commitment to helping children and families affected by type 1 diabetes. Beyond her remarkable talent, Dolly will be remembered for the kindness and joy she shared so generously with others. Our hearts are with her family, friends, and all who loved her as we celebrate her extraordinary life and lasting legacy. She will be deeply missed.    

What if the bottleneck in cell line development isn't how many clones you screen, but how you track them?Cloning workflows have long relied on brute force: screen more cells, automate harder, and hope that small-scale performance predicts manufacturability. But too often, the “perfect” clone in a 96-well plate turns into a dud when it reaches the bioreactor. That disconnect costs time, money, and promising therapies.This week, host David Brühlmann welcomes Kent Rapp, Co-founder and CEO of Biolinco, an entrepreneur who's turning the classic approach to cell line development inside out. Drawing from his background in chemical engineering and his work in biomanufacturing at Johns Hopkins University, Kent teamed up with DNA barcoding experts to pioneer a new workflow: barcode every cell, pool them, and track their true performance in the environment that matters.Topics discussed:The pitfalls of brute-force screening in traditional cell line development (03:05)Kent's background and how he was drawn to combine science, startups, and biomanufacturing (04:37)Overcoming discrepancies between small-scale and large-scale screening environments (08:30)How DNA barcoding allows for high-resolution, pooled clone screening (10:34)Sensitivity advantages of sequencing over plate-based detection (14:21)Methodology for tracking and recovering individual high-performing clones from pools (15:13)Impact on speed and workflow efficiency in cell line development (17:31)Regulatory and safety considerations related to DNA barcodes in cell lines (19:04)Smart insight: According to Kent, biotech as an industry has a tendency to "automate problems instead of solve them". Rather than addressing the root causes—like lack of meaningful measurements at relevant scales—companies often throw more robots and more plates at the issue, hoping brute force will finally yield the magical clone. But real process improvement requires a rethinking of what is being measured and how those insights are generated—not just a higher throughput of the same flawed assay.If this got you rethinking how you screen clones, you'll want these next. We've tackled cell line development, high-throughput screening, and the art of spotting manufacturable candidates early from a few different directions — here are four worth queuing up.Episodes 117 - 118 : Cell Line Development Secrets: Eliminating Critical Bottlenecks for Faster Timelines with Andrea GoughEpisodes 09 - 10: Revolutionizing Cell-Line Development: Unleashing the Power of Nanopens and Microenvironments with Tanner NevillEpisodes 123 - 124: Manufacturability: Why Most Protein Candidates Fail (And How to Pick Winners Early) with Susan SharfsteinEpisodes 115 - 116: Revolutionizing Biologics Development with Hyper Throughput Screening and AI with Jeremy AgrestiConnect with Kent Rapp:LinkedIn: www.linkedin.com/in/kent-rapp Biolinco website: www.biolinco.comFree 5-day email course, The CMC Failure Chain: the five recurring CMC mistakes that put your promising program at risk → Get it hereSupport the show

AI can now reproduce a person's face, voice, movement, and likeness with increasing realism. The bigger question is becoming: Who gets to control that identity, authorize its use, and potentially get paid when it has commercial value? In Episode #684 of the New Media Show,  Host Rob Greenlee talks with Anne Kavanagh, co-founder of Royall.ai, about building a new permission and licensing layer around human identity. The conversation is not about stopping or being anti-AI. It is about establishing something that has largely been missing: proof and authorization before use. Your Identity Becomes an Asset You Control Royall.ai is developing what Anne describes as a biometric vault where people can register elements of their identity, including voice, face, likeness, and body motion. Those assets can be fingerprinted and watermarked, creating the foundation for detecting use, approving or rejecting it, and potentially licensing it commercially. That changes the discussion from simply asking whether AI can clone someone to asking whether the person actually gave permission. A creator could potentially say: Use my voice for this campaign, but only for six months. Allow my likeness to be used to train this model, but pay me. Do not use my identity for this purpose at all. The central principle is simple: You own you. Protection and Opportunity The same technology designed to identify unauthorized use could also create legitimate new markets for human identity. Anne describes a future where AI companies, studios, agencies, platforms, and brands could license verified human data rather than simply collecting material from the public internet. Creators could choose whether their voice, face, movement, or content can be used for AI training and receive compensation when they opt in. This becomes especially important as synthetic media becomes indistinguishable from human media. Rob also raises another possibility: as AI-generated content becomes abundant, verified or certified human-created content may itself become more valuable. Podcast Archives Create Another Rights Problem The discussion gets particularly relevant to podcasting. A podcast owner may control thousands of hours of archived conversations, but that does not necessarily mean the owner has the right to license every guest's voice for AI training. Rob explains that the New Media Show archive has previously attracted interest for conversational AI training, but licensing complete conversations would require permission from the guests whose voices appear in them. Royall.ai is exploring infrastructure that could help identify those participants, request consent, manage permissions, and create licensing transactions across large content libraries. That could become a significant issue as decades of podcast, video, music, and creator archives become valuable training material. Discussion Highlights – Who should control your voice, face, and digital likeness – Creating a biometric identity vault – Consent before AI use – Detecting unauthorized likeness and voice usage – Licensing human identity for AI training – Getting creators paid for authorized use – Deepfakes, scams, and identity theft – Why trust is critical to biometric infrastructure – AI disclosure versus AI-assisted creation – The rise of verified human-created media – Creator contracts and synthetic likeness rights – Licensing podcast archives for AI training – Why guest consent matters – Royall.ai as an identity and permission API layer Chapter Timestamp Markers 00:00 Who controls your likeness and voice identity? 03:00 Introducing Anne Kavanagh and Royall.ai 07:00 How the idea behind Royall.ai developed 09:00 Verified identity, authorization and licensing 10:00 Creating a biometric vault for voice, face and motion 18:00 Detection, reporting and takedown tools 20:00 Opting into AI training and getting paid 24:00 Building a training-grade voice model 28:00 Identity protection becomes an economic opportunity 34:00 Why this is a human issue, not just a creator issue 38:00 Deepfakes, students, scams and identity theft 40:00 The trust challenge of storing biometric identity 43:00 Building a registrar for human identity and likeness 45:00 Royall.ai as part of the technology stack 48:00 The principle: You own you 53:00 AI tools, disclosure and audience trust 59:00 Could certified human content become premium? 01:02:00 Synthetic podcast hosts and transparency 01:04:00 Creator contracts and consent for AI training 01:05:00 Licensing podcast archives and guest voices 01:08:00 Who controls your existing content libraries? 01:11:00 How Royall.ai early access works 01:14:00 Public images, copyright and identity ownership Anne Kavanagh Guest Links Royall.ai is currently onboarding users through an early-access process, with registration, fingerprinting, watermarking, detection capabilities, and enterprise/API integrations discussed toward the end of the episode. Royall.ai https://royall.ai Host, Rob Greenlee and Show Links New Media Show https://newmediashow.com New Media Show on YouTube https://youtube.com/@TheNewMediaShow Rob Greenlee https://robgreenlee.com Rob Greenlee on LinkedIn https://www.linkedin.com/in/robgreenlee Podcast Hall of Fame https://podcasthall.com AI Disclosure AI tools helped organize and edit the episode to remove filler words; this description was created from the completed full transcript of episode #684. The recorded conversation, human performances, perspectives, editorial direction, and final responsibility for the episode remain with Rob Greenlee and Anne Kavanagh. The New Media Show is human-hosted.The post Own Your Identity: Who Controls Your Voice, and Likeness? | Anne Kavanagh, Royall.ai #684 first appeared on New Media Show.

In this episode, Lisandro Franky shares insights on conversion tracking mistakes, industry responses to AI, and best practices for digital marketing success.Key topicsConversion tracking mistakes and solutionsImpact of AI on marketing industryBest practices for campaign optimizationData analytics and anomaly detectionClient communication and transparencyChapters00:00 Introduction to Frankie and his background02:10 Frankie's experience with digital marketing and AI05:39 Common mistakes in conversion tracking09:09 Detecting and fixing tracking issues14:07 Human vs system errors in data feed20:22 Building anomaly detection platforms27:09 Fixing data feed issues in bidding platforms36:30 Importance of data granularity and account management44:28 Privacy and ethical considerations in AI use45:05 Frankie's advice for marketers facing tracking issuesFind Franky on LinkedIn and Mochee Join us on ⁠⁠⁠⁠⁠⁠⁠Slack⁠⁠⁠⁠⁠⁠⁠Subscribe to our ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Newsletter⁠⁠⁠⁠⁠⁠⁠⁠⁠

Have you ever wondered how trolls, bots, and paid influencers are quietly manipulating what you see online and why even smart, skeptical people fall for it? Today, disinformation expert Dr. Darren Linvill pulls back the curtain on the tactics that bad actors are using to try and shape our beliefs.    In this episode, Therese Markow and Dr. Darren Linvill discuss the various forms of digital deception and the strategies used by state actors to manipulate global discourse. Dr. Linvill distinguishes between misinformation, disinformation, and malinformation and gives examples of each, including tactics used by different international organizations from Iran, China, Israel, North Korea, and others. He also discusses the psychological impact that this disinformation has on humanity.     Key Takeaways: Fraud is the oldest form of disinformation, and it's rampant across social media. It's a multi-billion-dollar industry.  The main way that AI is being used right now to disseminate false information, disinformation, whether it's fraud or political disinformation, is the scale at which this content is created.  Sometimes there is not enough information to attribute disinformation accounts to a specific person or group. Sometimes it can be traced either through the content being posted or similar information on other websites.  At the end of the day, people will believe what they want to believe, regardless of whether it is true or has been fact-checked as false.    "At the end of the day, all of us humans are emotional animals. And we are interpreting the world around us, including the information we find on social media, through an emotional lens, especially when it comes to the communities that we're a part of, and our emotional attachments to those communities and our emotional needs that we derive from those communities, that absolutely affects the lens through which we interpret information." —  Dr. Darren Linvill   Episode References:  Clemson University Media Forensics Hub: Spot the Troll - https://spotthetroll.org/    Connect with Dr. Darren Linvill: Professional Bio: https://www.clemson.edu/cbshs/about/profiles/darrenl  Twitter: https://x.com/DarrenLinvill?lang=en   LinkedIn: https://www.linkedin.com/in/darren-linvill-6673655b  Google Scholar: https://scholar.google.com/citations?user=gQl4PlQAAAAJ&hl=en    Connect with Therese: Website:  www.criticallyspeaking.net Bluesky: @CriticallySpeaking.bsky.social Instagram: @criticallyspeakingpodcast Email: theresemarkow@criticallyspeaking.net   Audio production by Turnkey Podcast Productions. You're the expert. Your podcast will prove it. 

This NDSU Ag Minute features Fibena Mathew, NDSU Field Crops Pathologist and Rex Sun with Ag Systems and Bioengineering on the NDSU Campus. They visit with listeners about the technology being developed to detect problems in soybean fields before you can even see them. See omnystudio.com/listener for privacy information.

Dr. Eric Winer and Dr. Michael Cecchini of Yale Cancer Center discuss colorectal cancer which 156,000 people will be diagnosed with annually in the U.S. Visit: https://medicine.yale.edu/cancer/ Email: canceranswers@yale.edu Call 203-785-4095

Episode 265: Ryan Fuller started questioning online reviews after two terrible stays at highly-rated vacation rentals. Both had 4.9-star ratings. After Ryan posted negative reviews, the people behind each listing independently offered him £200 to change his review to five stars.  "It was disappointing," he said, "that clearly many people took them up on this offer." On the flip side, the experience explained something that had been bothering him for a while: Places with thousands of positive reviews could still turn out to be terrible. So Ryan, founder of Larrocos Labs and a serial entrepreneur, decided to investigate.  He built an AI system that has now analyzed hundreds of thousands of reviews covering roughly 22,000 restaurants. One example of what he found: In a focused analysis of 4,000 restaurants, about 70% showed at least one unusual review pattern. Some had sudden bursts of five-star reviews. He found one case in which roughly 100 reviews had been submitted within a two-minute period. Others featured suspiciously similar language, unusual concentrations of reviews mentioning particular employees, or reviewers whose histories raised questions about their credibility. None of that proves a review is fake. As Ryan explains, the goal is not to establish absolute truth, but to determine how much confidence we should place in what we are seeing. Ryan discusses what this means for consumers, platforms, and anyone relying on AI-generated information. He also explores an alternative: systems that show their work, identify potential sources of distortion, and tell us how confident they are rather than presenting uncertain conclusions as facts. He sums it up well: "I think we're living in a world where understanding what is real or what is true is going to become one of the most difficult problems for humans to deal with." Guest: Ryan Fuller, Founder, Larracos Labs  Host: Rob Markey, Partner, Bain & Company Give us feedback: Customer Confidential Podcast Feedback Send us a note: Contact Rob Timestamped Topics 00:39 – How two 4.9-star vacation rentals led Ryan to question online reviews 03:11 – Why hours spent researching restaurants became a problem worth solving 04:49 – Using AI to automate the process of assessing restaurant reviews 05:26 – Building a database of 22,000 restaurants in six months with 300 lines of code 06:15 – Finding unusual review patterns across 70% of a 4,000-restaurant dataset 07:20 – Identifying sudden clusters of ~100 reviews for one restaurant 08:10 – Treating suspicious review activity as a question of confidence 08:40 – Using repeated staff names and customer incentives as review signals 09:12 – Detecting reviews that describe offers of money for positive ratings 11:05 – Assessing reviewer credibility through history, photos, and detail 12:11 – Building an AI product that checks authenticity and extracts review data 13:01 – Evaluating restaurant experiences across 36 distinct dimensions Notable Quotes 18:00 "I think with AI, it's like rocket fuel, where things can be done at incredible scale and with high degrees of believability in ways that were never true before. I think we're living in a world where understanding what is real or what is true will become one of the most difficult problems for humans to deal with on even just everyday stuff like picking a restaurant." 26:00 "Platforms that start to be more transparent about sources and degree of confidence and potential risks for any information they're providing will become more popular." 28:00 "It's almost just like an arms race. There's no sudden advance in tech or approach that's gonna solve the problem. I'm just pontificating here; I don't have good answers, but I do think this is maybe the problem of our time." 33:00 "The devious thing about AI is that it sounds so credible; we're going through a transitional phase where we're not as well attuned to what the tells are when confidence isn't there." 37:00 "I always try to show the work. One thing we do is we have a letter grade that we assign each restaurant for overall quality. So, it can be an A, a B-plus, whatever. And the very first thing underneath the score, the overall letter, is why it got a B-plus." Additional Resources Read Ryan Fuller's analysis of unusual patterns and manipulation in London restaurant reviews: https://www.linkedin.com/posts/ryantfuller_london-ai-share-7399118135099973633-Iquu/ See Ryan Fuller's restaurant data visualizations and discussion of how platform algorithms shape restaurant visibility: https://www.linkedin.com/posts/ryantfuller_datavisualization-londonlife-urbananalytics-ugcPost-7404913381431844864-cM7l/ Here's the article referenced about how a man created his own top-rated Dulwich restaurant: I Made My Shed the Top Restaurant on TripAdvisor: https://www.vice.com/en/article/i-made-my-shed-the-top-rated-restaurant-on-tripadvisor/

Identity theft red flags are no joke. From a suspicious looking email, to an alarming text message, learning how to detect fraud before it happens is a critical skill we all need to develop. Detecting fraud before or even during an event can make a big difference in determining how much time and resources you'll need to spend fixing the damage done.   Links: Download and use the Check Fraud Detection Checklist Learn more about and sign the America Saves Pledge Check out TCU University for financial education tips and resources! Follow us on Facebook, Instagram and Twitter! Learn more about Triangle Credit Union Transcript: Welcome to Money Tip Tuesday from the Making Money Personal podcast.   This week we're sharing a tip from the America Saves Check Fraud awareness campaign focused on how to detect fraud, particularly check fraud early, so you can act quickly to stop fraudsters in their tracks before too much damage is done. Take a moment, listen in, and share it with others so they can be made aware of this ongoing financial threat.  Whether a check was stolen from the mail, altered, forged, or used in a scam, the sooner you notice suspicious activity, the better your chances are of limiting financial loss and protecting your account. The challenge? Check fraud is not always obvious right away.   A payment may seem delayed. A check might clear for the wrong amount. Or you may notice a transaction you don't recognize weeks later. That's why regular account monitoring matters. Here's how to spot the warning signs of check fraud and what to do if something doesn't look right.   Warning Signs of Check Fraud   Fraud often leaves some clues. Knowing what to look for can help you act quickly.   1. A Check Hasn't Been Cashed When You Expected It To   If you mailed a payment and it has not been processed within the normal timeframe, it is worth checking on. This does not always mean fraud, but it could mean the check was delayed, lost, or intercepted.    What to do: Start by contacting the person or company you paid, and confirm whether they've received it or not.    2. A Check Clears for the Wrong Amount   One of the clearest warning signs is a check clearing for more (or less) than you wrote it for. This may happen in cases of check washing or altered checks.   What to do: Compare your check register or payment records to your account statement, and review the check image. Most financial institutions provide them through online banking, or you can request them at your local branch or customer service line.     3. You See a Payment to Someone You Don't Recognize   If your account shows a check made out to a person or business you did not authorize, that could be a sign of fraud. This may happen with forged or altered checks.   What to do: Review the transaction details immediately, and contact your financial institution right away    4. Missing Checks or Missing Mail   If checks from your checkbook are missing or you notice missing mail, it may signal theft. Stolen blank checks can be used fraudulently.   What to do: Secure your remaining checks; report missing checks to your financial institution and any missing mail to the post office.     5. Unfamiliar Withdrawals or Account Activity   Not all fraud appears as a check image. Sometimes fraud starts with stolen account information and shows up as other account activity.   What to do: Watch for small test transactions, unusual withdrawals or multiple failed payment attempts.    Simple Ways to Monitor Your Accounts   The best way to catch fraud early is to make account monitoring a regular habit. It does not have to take long.   Set Up Account Alerts   Most financial institutions allow you to set up alerts for withdrawals, deposits, checks clearing, low balances and large transactions. These alerts can help you spot suspicious activity quickly.    If you are not comfortable using mobile banking, ask your financial institution if they offer phone, text or email alerts.   Review Your Account Weekly   A quick weekly review can help you catch issues before they grow. Check for payments you don't recognize, checks clearing for the wrong amount, or missing expected transactions. Even five minutes can help.   Check Your Cleared Check Images   Many financial institutions allow you to view images of checks that have cleared. Look for the correct payee, correct amount, and your actual signature. This can help spot altered or forged checks.   Keep a Simple Record of Checks You Send   Whether it's a checkbook register, a notebook, or a note on your phone, tracking helps. Record the date you sent the payment, the amount and the recipients information. That makes it easier to compare later.   Be Careful with Unexpected Checks   If you receive a check you were not expecting, especially tied to a job, prize, or payment request….pause! Ask questions before depositing it. Unexpected money is often a warning sign.     What to Do If You Notice Something Suspicious   If you think something may be wrong, act quickly.   Step 1: Contact Your Financial Institution    Review what you've noticed with them. They can assist with freezing or flagging the account and transaction, place a stop payment or investigate the issue further. The sooner you contact them, the better.   Step 2: Gather Your Records   Collect check numbers, account statements, payment records, and any related emails, text, or related messages. Having information ready can speed up the process.   Step 3: Monitor Closely   After reporting suspicious activity, keep watching your account. Fraud sometimes happens in more than one transaction.   Step 4: Change Account Security If Needed   Depending on the situation, it may be recommend that you close your account and open a new one, update passwords or add extra account protections.    Early Action Can Make a Big Difference   Check fraud can be stressful but early detection gives you more options.   The key is simple:   Review your account regularly   Pay attention to missing or unusual transactions   Act quickly if something feels off    Small habits can help protect your money. Download our check fraud detection checklist to help monitor your account, track payments, and catch suspicious activity sooner.   If you're ready to learn more about how small steps can help build your financial confidence, take the take the America Saves Pledge today. It's a simple commitment to save for what matters most to you, one step at a time.    

What if vascular disease could be detected years earlier, before patients face the most serious consequences?In this episode of Entrepreneur Rx, host John Shufeldt sits down with Josh Hanson, founder and CEO of ImageAiD, a Jetstream Venture Fund portfolio company, to discuss his path from biomedical engineering student to healthcare entrepreneur. Josh shares how growing up in Rochester, Minnesota, surrounded by Mayo Clinic and a culture of healthcare innovation, shaped his desire to build technology that could help save lives. The conversation explores the problem ImageAiD is working to solve: diagnosing peripheral artery disease, or PAD, earlier and at scale. Josh explains how ImageAiD combines handheld Doppler ultrasound, cloud-based software, and AI to help clinicians capture and analyze blood flow waveforms in minutes, reduce diagnostic variability, and identify vascular disease risk earlier. John and Josh also discuss Mayo Clinic mentors, ASU's Biodesign training, building for all healthcare stakeholders, and turning peer-reviewed research into a platform that can reach patients. Beyond the technology, the episode covers entrepreneurship at a young age, imposter syndrome, humility, mentorship, and the courage to simply start. About Josh Hanson: Josh Hanson is a biomedical engineer, entrepreneur, and founder focused on advancing cardiovascular diagnostics through medical technology and AI. As founder and CEO of ImageAiD, he is leading the development of an AI ultrasound platform designed to improve early detection of peripheral artery disease and broader cardiovascular risk. His work has been shaped by experience at Mayo Clinic's Gonda Vascular Center, ASU's biomedical engineering program, and the Mayo Clinic and ASU Alliance for Health Care's IMPACT Program, where he trained in the Biodesign process. About ImageAiD: ImageAiD is a medical technology company developing a handheld Doppler ultrasound platform that combines portable hardware, cloud-based software, and AI to make vascular disease easier to detect before it causes life-altering complications. The platform is designed to capture and analyze blood flow waveforms in minutes, helping clinicians identify signs of peripheral artery disease and better understand a patient's risk of serious cardiovascular events, including heart attacks, strokes, and amputations. Initially focused on PAD, ImageAiD aims to make vascular diagnostics faster, more consistent, and more accessible in settings where traditional vascular testing may not be available. About Xcellerant Ventures: Xcellerant Ventures is a venture capital firm that invests in innovative companies across healthcare, technology, defense, and other emerging industries. Through multiple funds and investment vehicles, including the Jetstream Venture Fund, Xcellerant partners with visionary founders, provides strategic guidance, and helps connect investors with opportunities in the private markets. About Jetstream Venture Fund: Jetstream Venture Fund is an interval fund managed by Xcellerant Ventures, that seeks to provide investors access to early-stage, high-growth companies with flexible terms, lower minimums ($5,000 minimum), and no carried interest. Jetstream is one of the first funds of its kind, bringing venture-style investing opportunities to a wider professional audience. Disclosure for Jetstream: Investors should carefully consider the investment objectives, risks, charges, and expenses of the Fund before investing. The prospectus contains this and other information about the Fund and can be obtained by emailing jetstream@sweaterfunds.com or by visiting www.jvf.vc. Please read the prospectus carefully before investing. 

Search "dark web" and you get the same spooky iceberg explainer a thousand times over. Useless if you already run infrastructure. This is the one nobody makes: how a blue team actually does dark web monitoring — how you watch for your company's leaked credentials, catch Tor traffic leaving your own network, and turn a scary alert into a defensible plan.Built for the IT pro moving into defense: sysadmins, network engineers, help desk, cloud, and infrastructure folks. Most of what makes dark web monitoring work isn't hacker magic — it's the network and endpoint fundamentals you already touch every day, pointed in a new direction.⏱️ CHAPTERS0:00 Your login might already be for sale0:50 Who this is for1:30 Surface, deep, and dark web — the version a defender needs3:20 Why you can't just Google your leaked data5:20 The 4 signals real monitoring watches for7:50 Detecting the dark web on your OWN network10:20 DIY vs. professional monitoring — the honest answer11:50 Turn the alert into a plan: Inventory → Threats → Controls → Scale14:10 You're not starting from zero

Angela DiFulvio explains a theoretical method for detecting nuclear weapons in low Earth orbit to prevent catastrophes like the 1962 Starfish Prime experiment, which destroyed a third of existing satellites. She describes an "inspector" satellite designed to induce a unique radioactive signature from fissile material using high-energy protons. DiFulvio details technical challenges, such as "pulse shape discrimination," to distinguish weapon-related neutrons from background cosmic radiation in the harsh space environment. She suggests that an international agency like the IAEAmight oversee these inspectors to ensure space remains weapon-free. DiFulvio emphasizes that while tests can occur in classified environments, more research is needed on the survivability of sensing electronics. She warns that a modern orbital nuclear detonation would be catastrophic for global infrastructure, specifically mentioning the vulnerability of massive constellations like Starlink. (8)

AI is changing hiring in ways that go far beyond candidates using ChatGPT to answer interview questions. The harder problem is knowing whether the person on screen is actually who they claim to be, whether their answers are their own, and what happens if someone with malicious intent gets access to company systems.Yagub Rahimov, CEO and founder of Polygraf AI, joins The Tech Trek to discuss the growing trust problem surrounding AI assisted interviews, deepfakes, impersonation, and security. He explains why organizations need more visibility into the hiring process without turning every unusual behavior, accent, or response into a reason for suspicion.What You'll Take Away• AI interview fraud is not simply a recruiting problem. Once someone enters the company, identity and access become security concerns.• Detecting suspicious candidates based on human intuition alone can create false positives. Rahimov argues for using technology to create evidence and visibility.• Small pieces of public information can reveal far more about a company than leaders realize when they are combined through what Rahimov calls mosaic intelligence.• Protecting company information means thinking beyond traditional security controls to what employees, executives, and systems expose publicly.Key Moments02:27 How AI tools can turn legitimate technology into an interview cheating mechanism05:35 Why hiring fraud can become a security and data access problem07:43 Using voice, conversation context, and AI detection to improve visibility during interviews11:43 Why increased AI uncertainty should not lead companies to distrust everyone14:28 What organizations should think about after a candidate actually gets hired19:40 The continuing race between increasingly capable deepfakes and detection technologyOne Line That Stuck“Tech problems have tech solutions.”Follow The Tech Trek for more conversations about AI, engineering, data, product, and how technical teams are adapting.

Point-of-care ultrasound (POCUS) is rapidly transforming emergency medical services, stepping up as the modern equivalent of the 12-lead ECG for today's paramedics, according to Dr. Ross Prager. While portable ultrasound technology was initially developed to miniaturize heavy hospital equipment for field use, widespread adoption faced friction due to complex training demands and accuracy drop-offs in fast-paced environments. AI integration directly tackles these scaling bottlenecks by guiding real-time image acquisition and providing high-level diagnostic interpretation.   By automatically identifying critical structures like the pleural line or organ interfaces, AI helps paramedics capture crisp, reliable views—even under chaotic field conditions with severe glare, heat, or noise. For trauma and undifferentiated dyspnea calls, prehospital ultrasound delivers vital objective data. Detecting free abdominal fluid or absent lung sliding allows EMS teams to notify receiving trauma centers immediately. This clinical head start mobilizes blood banks, surgical staff, and operating rooms before the ambulance even arrives, cutting down critical time to definitive care.

John Karageorge, head of S&P's activist defense surveillance group, discussed how corporations can identify activist accumulations before they become public. 

João Moura built a fraud detection platform operating in 188 countries not by making fraud prevention safer, but by turning it into a growth lever. This conversation gets into how organized crime runs modern fraud, why siloed data guarantees you'll lose, and how connecting institutions across borders changes everything.What you'll learnWhy 70% of fraud today is backed by organized crime networks, and what that means for your detection strategy (02:46)How mule accounts operate as layered networks across institutions and why catching one account misses the point (32:20)What false declines actually cost you in revenue, customer trust, and operational overhead (09:03)How fraud detection becomes a growth enabler when it lets acquirers onboard merchants same-day with confidence (20:19)Why connecting data across institutions creates a network effect that makes every client's fraud model stronger (28:40)What the third generation of AI-powered fraud detection looks like and why it's fundamentally different from siloed models (14:45)How agentic AI introduces a new authorization problem that nobody in payments has solved yet (37:15)What João learned about distribution, decisiveness, and sunk cost fallacies after spinning Fraudio out of a bank (46:20)TIMESTAMPS1:35 João's background: 20 years in AI before it was cool2:46 How organized crime powers modern fraud7:55 The real cost of false declines on revenue and customers14:45 Three generations of AI fraud detection explained16:34 How generative AI acts as a force multiplier for fraud teams20:19 Detecting fraudulent merchants before chargebacks arrive25:13 How much fraud Fraudio actually stops: the numbers28:40 The Philippines rule that becomes available to 188 countries32:20 Why mule accounts are really mule networks37:15 Agentic AI and the unresolved authorization problem43:30 The lazy insight that became Fraudio46:20 What João learned: distribution, decisiveness, and sunk cost fallacies

Siyabonga Motha, standing in for Aubrey Masango, speaks to Brad Latilla-Campbell, Country Manager at Crimson Education, on why universities across the world are dropping AI detection tools. They also touch on the future of higher education that now incorporates artificial intelligence and how that will work in industry. You’re listening to The Aubrey Masango Show with Aubrey Masango, where real conversations meet expert insights – from politics to life, personal finance, and more. Thanks for listening. Listen live on 702 weekdays from 8 pm to midnight, or on CapeTalk from 8 pm to 9 pm (South African time) https://buff.ly/gk3y0Kj For more from the show and catch-up podcasts, visit Primedia+ here https://buff.ly/gk3y0Kj Subscribe to the 702 Daily and Weekly Newsletters https://buff.ly/v5mfetc Keep the conversation going online: 702 on Facebook: https://www.facebook.com/TalkRadio702 702 on TikTok: https://www.tiktok.com/@talkradio702 702 on Instagram: https://www.instagram.com/talkradio702/ 702 on X: https://x.com/Radio702 702 on YouTube: https://www.youtube.com/@radio702 CapeTalk on Facebook: https://www.facebook.com/CapeTalk CapeTalk on TikTok: https://www.tiktok.com/@capetalk CapeTalk on Instagram: https://www.instagram.com/capetalkza/ CapeTalk on X: https://x.com/CapeTalk CapeTalk on YouTube: https://www.youtube.com/@CapeTalk567 See omnystudio.com/listener for privacy information.

Sponsor Link:NordVPN - Safeguard your online activity with our exclusive offer for Space Nuts listeners. Visit www.nordvpn.com/spacenuts for details.From SpaceX Nuclear Experiments to Galactic DiscoveriesJoin host Andrew Dunkley and astronomer Fred Watson as they explore some of the most fascinating topics in space science, from innovative nuclear power tests in space to the expanding boundaries of our galaxy. Whether you're an astrophotography enthusiast or a space policy advocate, this episode delivers insights that broaden your cosmic perspective.In this episode:SpaceX's recent CubeSat launch featuring a tritium-based nuclear power source for space applicationsThe potential and safety considerations of nuclear energy in space missionsThe possibility of nuclear weapons detection in space using neutron sensors and passive radiation monitoringThe intriguing hypothesis of dark matter stars and their potential signaturesThe mystery surrounding Earth's dust origins—cosmic spherules and their unknown sourcesNew research indicating our galaxy's spiral arms are about 10% longer than previous estimates, based on light echoes from gamma ray burstsThe rise of smart telescopes and their role in making astrophotography more accessible for amateursTimestamps:(00:00) Introduction and overview of today's headlines(02:00) SpaceX's CubeSat with tritium power source—what's happening?(04:33) Nuclear power in space: Safety and future applications(11:03) Detecting nuclear weapons in space: Challenges and innovations(22:45) Earth's dust origins: Micro-meteorites and cosmic spherules explainedResources & Links:SpaceX's CubeSat nitrogen launch storyBeta-voltaic nuclear power technologyNASA's Chandra X-ray ObservatoryUniverse Today article on Milky Way mappingJames Webb Space Telescope and dark matter researchScience Advances publication on Earth's micrometeoritesConnect with Fred Watson:LinkedInTwitterEnjoying the show? Support us on Patreon and leave a review on your favorite podcast platform.Thanks for tuning in and keep looking up!Become a supporter of this podcast: https://www.spreaker.com/podcast/space-nuts-astronomy-insights-cosmic-discoveries--2631155/support.

Join us tonight with detectorist Andy Hughes to discussing his amazing gold torc over 3000 years old find among other amazing things he has found.Sponsored by Metal Detecting NewsBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-big-detecting-show--3690873/support.

What happens behind the scenes to ensure new therapies are safe for patients? In this episode of Moving Medicine Forward, we are joined by John Kane, Vice President of Pharmacovigilance and Safety Services at CTI, to explore the critical role of drug safety throughout the clinical development process. John shares how safety teams collect and evaluate adverse event data, navigate complex global regulations, and help protect patients from clinical trials through post-market surveillance. He also discusses the growing impact of AI in pharmacovigilance, the continued growth of North Carolina's Research Triangle, and the rewarding career opportunities available in clinical research. 01:13 – Finding a Career in Clinical Research John shares how he transitioned from nursing into the clinical research industry.  02:14 – CTI's Growth in Raleigh Why North Carolina's Research Triangle continues to attract biotech companies and research talent. 04:55 – Understanding Pharmacovigilance What pharmacovigilance is and how safety teams collect, evaluate, and report adverse events throughout a drug's lifecycle. 07:33 – Protecting Patients Through Drug Development How CTI safety teams monitor risks, identify safety signals, and communicate important findings to regulators and investigators. 09:55 – Navigating Global Regulations The growing complexity of global safety reporting requirements and regulatory compliance. 11:51 – The Role of AI in Drug Safety How AI may improve data processing, signal detection, and scientific literature review. 13:53 – A COVID-19 Success Story John reflects on supporting a large COVID-19 trial and managing high volumes of safety data. 14:38 – Collaboration at CTI Why teamwork and collaboration are key to successful clinical trials and patient impact.  15:32 – Advice for Future Research Professionals Career opportunities in clinical research and how CTI helps new professionals enter the field.

Discoveries on Mars, the Hubble Tension, and Dark Photons - Space Nuts EpisodeJoin Andrew Dunkley and Professor Fred Watson as they explore the latest developments in space science—from evidence of complex organic molecules found by the Perseverance rover on Mars that may hint at past life, to the ongoing mystery of the Hubble tension that challenges our understanding of the universe's expansion. Plus, a deep dive into the elusive concept of dark photons and their potential role in explaining dark matter.Key Topics:The significance of complex carbon molecules detected in Martian rocks by Perseverance and their implications for extraterrestrial lifeThe challenges and prospects of returning samples from Mars and the influence of upcoming Chinese missionsUnderstanding the Hubble tension: different measurements of the universe's expansion rate and what they could mean for new physicsThe role of gravitational wave observations in refining the Hubble constant and resolving cosmological discrepanciesAn introduction to dark photons: what they are and their potential connection to dark matter and dark energyThe nature of cosmic redshift, light travel time, and how we look back in cosmic historyThe possibility of the universe expanding into higher dimensions or higher-dimensional multiversesThe shape and boundaries of the universe: flat, spherical, or saddle-shaped?Resources & Links:Science Advances Paper on Martian Organic MoleculesNASA Perseverance RoverCosmological Parameters and Hubble TensionLarge Hadron Collider Official SiteDark Photons and Dark Matter — University of CaliforniaBiteStop Streaming ServiceConnect with Fred Watson:Professor Fred Watson - LinkedInProfessor Fred Watson - TwitterNote:Stay tuned for future episodes where we continue exploring mysteries of the cosmos, and don't forget to visit our website to send questions or feedback!Become a supporter of this podcast: https://www.spreaker.com/podcast/space-nuts-astronomy-insights-cosmic-discoveries--2631155/support.

What do you do when you've built the technology first and the first customer who tries it tells you it's not working at all?Prashant Warrier is the first PhD and the first scientist on Unstarted. A steel-town kid from Bhilai who went from IIT Delhi to a PhD in AI, he came back to India because of a stolen passport — and built Qure.ai, whose AI reads chest X-rays for TB and lung cancer across the world.In this episode, Avnish and Prashant attempt to answer: 1. How do you identify a unique problem is it about passion or market cap?2. How do you know the technology is actually working? 3. How can founders assess whether they're early, late, or correctly timed for a market? 4. Will frontier AI kill vertical businesses or is there domain-specific stuff left to build? 5. Why build a cutting-edge AI company from Mumbai?This episode is in partnership with TEAM — Tech Entrepreneurs Association of Mumbai.Chapters 00:00 Introduction1:41 Steel town to IIT to a PhD in AI3:20 SAP, and the stolen passport that sent him home6:32 Freedom over the US visa rat race8:17 The 2012 breakthrough that started the company11:43 A research lab with no business plan13:33 "A solution looking for a problem"16:52 The reality check & the real bottleneck19:20 TB screening: 4 weeks to 30 seconds21:43 Detecting lung cancer early with AI24:23 Moats, ChatGPT & the future of AI in healthcare32:04 Why Mumbai, and advice to founders

Join Dave and Donner and this week's guest, YouTuber - Chrissy Detects. Learn all about her recent gold and rally visits.Become a supporter of this podcast: https://www.spreaker.com/podcast/the-big-detecting-show--3690873/support.

This episode is built around a ransomware response checklist — a three-part Reddit series by a security specialist who goes by snorkel42, breaking down exactly how to prevent, contain, and recover from a ransomware attack.This is an encore episode, and it's back not just because a lot of people downloaded it originally, but because so many of you listened all the way through — some of you more than once. That kind of engagement told us this one was worth bringing back.Curtis Preston and Prasanna Malaiyandi dig into snorkel42's series, which breaks the whole problem into three parts: how to stop ransomware from getting in, how to slow it down if it does, and what to actually do once you've been hit. Curtis and Prasanna go section by section — covering phishing and dropper prevention, application whitelisting, blocking lateral movement between servers, locking down RDP and SSH, honeypot files for catching intruders in the act, and building a real incident response plan before you ever need one.They also get into the messier parts most people don't talk about — what it's actually like to negotiate for a decryption key, why getting your data back isn't the end of the story, and why a ransomware attack is nothing like a normal disaster recovery scenario. Along the way, Curtis makes the case that most organizations already have the gaps this attacker needs — and that fixing them now is a lot cheaper than fixing them after the fact.Whether you're building your first incident response plan or just want to stress-test the one you've already got, this episode gives you a practical, section-by-section framework to work from.Chapter Markers:00:00 – Encore intro & episode setup00:01:37 – Show intro and banter00:06:21 – Preventing the breach: phishing, droppers, and whitelisting00:14:46 – Blocking lateral movement, RDP/SSH lockdown00:20:28 – Detecting exfiltration and honeypot files00:24:19 – What to do once you've been hit00:25:58 – Building your incident response plan00:30:43 – Decryption, ransom payments, and why it's not over yet

SpaceTime Series 29 Episode 85 Detecting nuclear weapons in space New modelling says small cube-sat sized spacecraft not much bigger than a fridge could be used to detect the presence of nuclear weapons on satellites in space. NASA's rescue mission to save the Swift space telescope reaches orbit NASA's Swift re-boost rescue mission is finally on its way to intercept the gamma ray space telescope and try to save it from its fiery fate. Stopping astronauts from wanting to kill each other on long space trips It can be tough enough getting on with family members at home or the people you have to work with – but imagine what it will be like if you're stuck with a small group of people on a multi-year mission to Mars. The Science Report A new study indicates that people who speak more than one language seem to have younger brains. Warnings that two thirds of Australian adults and a quarter of kids are now overweight or obese. Half of all fatal electric scooter accidents in Sweden are caused by drunk riders. Great news for chocolate lovers with 4 new species discovered. Skeptics guide to the case of the missing peacock.   Our Guests This Week: Professor Chris Kirkland from Curtin University NASA planetary geologist Cynthia Phillips Professor Dorothy Carter from Michigan State University   And our regular guests: Alex Zaharov-Reutt from techadvice.life Tim Mendham from Australian Skeptics  

Join Dave and Adrian with Terry Read to discuss the BIG Dig metal detecting rally over the 21st - 23rd August this yearBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-big-detecting-show--3690873/support.

What changes for you as a developer when the device moves from your pocket to your face? The battery shrinks by an order of magnitude, the thermal budget is whatever won't make your nose uncomfortable, and your mental model of "one process, one device" goes out the window. Rey and Dmitrii talk us through their custom power monitors, how they've extended Perfetto to give a coherent trace across a multi-device system, why robotic arms make surprisingly good QA engineers, and what it takes to catch the kind of regression that quietly costs you thirty minutes of call time. All of this and more is discussed in this episode. Got feedback? Send it to us on Threads (https://threads.net/@metatechpod), Instagram (https://instagram.com/metatechpod) and don't forget to follow our host Pascal (https://mastodon.social/@passy, https://threads.net/@passy_). Fancy working with us? Check out https://www.metacareers.com/. Links Migrating Data Ingestion Systems at Meta Scale: https://engineering.fb.com/2026/05/12/data-infrastructure/migrating-data-ingestion-systems-at-meta-scale/  Timestamps Intro 0:05 Introduction and Setup 1:51 Battery Life Optimization in AI Glasses 1:57 Challenges in Testing and CI Architecture 5:37 Detecting and Managing Power Regression 8:27 Developer Tools and Best Practices 13:04 Advanced Monitoring and Synchronization Techniques 16:53 Advanced Power Monitoring in Wearables 21:26 Real-World Examples of Performance Optimization 23:53 Battery Life Improvements Through Engineering 25:21 Engineering Culture and Performance Mindset 27:49 Continuous Testing and Profiling Strategies 29:36 Balancing Profiling Overhead and Accuracy 32:15 Simulating Real-World Scenarios in Testing 34:27 Best Practices for Efficient Wearable Code 37:21 Outro 40:26  

The 40 Most Rage-Inducing Problems in Tech, ZFS vs Cep, Detecting and removing dangerous secrets on dev workstations before Shai-Hulud does and more... NOTES This episode of BSDNow is brought to you by Tarsnap and the BSDNow Patreon Headlines The 40 Most Rage-Inducing Problems in Tech ZFS vs Ceph: Do You Actually Need Ceph? News Roundup Detecting and removing dangerous secrets on dev workstations before Shai-Hulud does FreeBSD sh for MacOS syslogd(8) privileged and non-privileged parts now separate binaries Getting Victoria Logs running on FreeBSD Tarsnap This weeks episode of BSDNow was sponsored by our friends at Tarsnap, the only secure online backup you can trust your data to. Even paranoids need backups. Feedback/Questions Send questions, comments, show ideas/topics, or stories you want mentioned on the show to feedback@bsdnow.tv Join us and other BSD Fans in our BSD Now Telegram channel

Could a blood test finally provide answers for millions living with chronic fatigue syndrome (CFS/ME)? In this episode, Alexandre Akoulitchev and Dmitry Pshezhetskiy reveal a groundbreaking approach using epigenetic biomarkers to detect biological signatures associated with this complex, hard-to-diagnose condition. Their work leverages cutting-edge molecular medicine and translational research to provide earlier, more objective detection of CFS/ME—offering hope for patients who have long struggled with uncertainty and delayed diagnoses. In this conversation, we explore: ·       How a blood-based biomarker test may identify chronic fatigue syndrome more reliably. ·       The role of epigenetics in understanding invisible, multi-system illnesses. ·       The four core symptoms of CFS/ME and why conventional diagnostics often fail. ·       How inflammation and immune signals contribute to fatigue and disease progression. Alexandre Akoulitchev, cofounder of Oxford BioDynamics and creator of the EpiSwitch biomarker platform, and Dmitry Pshezhetskiy, Professorial Research Fellow at Norwich Medical School, bring decades of expertise in molecular biology, genome regulation, and translational research to this discussion. Learn more about Alexandre Akoulitchev here and Dmitry Pshezhetskiy here. Episode also available on Apple Podcasts: https://apple.co/38oMlMr 

We've had endless conversations about aliens and first contact--but what if a conversation with other intelligences is beyond our scope? Dr. Daniel Whiteson, particle physicist at CERN's Large Hadron Collider and professor at UC Irvine, joins us to explore less conventional thoughts on first contact. We look at the challenges of communicating with extraterrestrial intelligences, potential difficulties of communicating via non-terrestrial mathematics and physics, and the possibility that extraterrestrials might actually be terrestrial... but existing as denizens of the dark energy universe. One might be sitting in your lap right now! Join us for the far-ranging discussion. Headlines: Boeing's Troubled Starliner Spacecraft Faces Further Setbacks and Delays NASA Perseverance Rover Finds Promising Clues of Ancient Life on Mars NASA Space Telescope Faces Fiery Descent, Mission Planned to Save It Main Topic: Dark Matter, Particle Physics, and the Search for Extraterrestrial Intelligence UC Irvine's Dr. Daniel Whiteson Discusses Path into Space Science and Particle Physics Exploring Nontraditional Signals for Alien Communication Beyond Radio Waves The Mystery of Ultra-High Energy Particles and Speculation on Artificial Cosmic Rays Challenges of Detecting, Interpreting, and Interacting with Alien Intelligence Implications of Dark Matter for Hidden Civilizations and Parallel Existence Complexities in Communicating with Truly Alien Life and Human-Centric Scientific Assumptions Hosts: Rod Pyle and Tariq Malik Guest: Daniel Whiteson Download or subscribe to This Week in Space at https://twit.tv/shows/this-week-in-space. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit

We've had endless conversations about aliens and first contact--but what if a conversation with other intelligences is beyond our scope? Dr. Daniel Whiteson, particle physicist at CERN's Large Hadron Collider and professor at UC Irvine, joins us to explore less conventional thoughts on first contact. We look at the challenges of communicating with extraterrestrial intelligences, potential difficulties of communicating via non-terrestrial mathematics and physics, and the possibility that extraterrestrials might actually be terrestrial... but existing as denizens of the dark energy universe. One might be sitting in your lap right now! Join us for the far-ranging discussion. Headlines: Boeing's Troubled Starliner Spacecraft Faces Further Setbacks and Delays NASA Perseverance Rover Finds Promising Clues of Ancient Life on Mars NASA Space Telescope Faces Fiery Descent, Mission Planned to Save It Main Topic: Dark Matter, Particle Physics, and the Search for Extraterrestrial Intelligence UC Irvine's Dr. Daniel Whiteson Discusses Path into Space Science and Particle Physics Exploring Nontraditional Signals for Alien Communication Beyond Radio Waves The Mystery of Ultra-High Energy Particles and Speculation on Artificial Cosmic Rays Challenges of Detecting, Interpreting, and Interacting with Alien Intelligence Implications of Dark Matter for Hidden Civilizations and Parallel Existence Complexities in Communicating with Truly Alien Life and Human-Centric Scientific Assumptions Hosts: Rod Pyle and Tariq Malik Guest: Daniel Whiteson Download or subscribe to This Week in Space at https://twit.tv/shows/this-week-in-space. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit

We've had endless conversations about aliens and first contact--but what if a conversation with other intelligences is beyond our scope? Dr. Daniel Whiteson, particle physicist at CERN's Large Hadron Collider and professor at UC Irvine, joins us to explore less conventional thoughts on first contact. We look at the challenges of communicating with extraterrestrial intelligences, potential difficulties of communicating via non-terrestrial mathematics and physics, and the possibility that extraterrestrials might actually be terrestrial... but existing as denizens of the dark energy universe. One might be sitting in your lap right now! Join us for the far-ranging discussion. Headlines: Boeing's Troubled Starliner Spacecraft Faces Further Setbacks and Delays NASA Perseverance Rover Finds Promising Clues of Ancient Life on Mars NASA Space Telescope Faces Fiery Descent, Mission Planned to Save It Main Topic: Dark Matter, Particle Physics, and the Search for Extraterrestrial Intelligence UC Irvine's Dr. Daniel Whiteson Discusses Path into Space Science and Particle Physics Exploring Nontraditional Signals for Alien Communication Beyond Radio Waves The Mystery of Ultra-High Energy Particles and Speculation on Artificial Cosmic Rays Challenges of Detecting, Interpreting, and Interacting with Alien Intelligence Implications of Dark Matter for Hidden Civilizations and Parallel Existence Complexities in Communicating with Truly Alien Life and Human-Centric Scientific Assumptions Hosts: Rod Pyle and Tariq Malik Guest: Daniel Whiteson Download or subscribe to This Week in Space at https://twit.tv/shows/this-week-in-space. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit

Know the red flags of human traffickingWith the 2026 FIFA World Cup in the news, public safety agencies, anti-trafficking task forces, advocacy organizations, and media outlets are raising concerns about the potential for increased human trafficking activity surrounding a major international sporting event. Human trafficking remains a persistent danger in communities around the world, and is often closer to home than you'd think. In this episode, we sit down with Amanda Elkanick Oder of the Texas Advocacy Project to explore how banks and credit unions can help detect human trafficking and even support survivors as they rebuild their financial lives.Listen in to learn what key words and phrases frontline staff should be trained to investigate further, what challenges survivors of human trafficking face after leaving abusive situations, and how new payment rails are impacting the way human traffickers operate. Amanda also shares what training Texas Advocacy Project can offer financial institutions looking to shore up their communities against trafficking and how transaction data can also be an indicator of a financially abusive situation.About the guest:Amanda Elkanick Oder is the Chief Advocacy and Education Officer at Texas Advocacy Project, a statewide nonprofit law firm providing free legal and social services to survivors of domestic violence, sexual assault, stalking, and human trafficking. A nationally recognized leader in the movement to end abuse, Amanda brings over 20 years of experience in program development, public policy, and systems advocacy. She leads statewide training initiatives, advances legislative strategies, and builds enduring cross-sector partnerships to expand access to justice. Amanda regularly presents at national and statewide conferences and serves on multiple task forces focused on legal reform, systems advocacy, coordinated community response to violence, and maternal health equity.Helpful links:Texas Advocacy Project training and outreach resourcesThe FIFA World Cup and human trafficking: Know the red flagsHuman trafficking awareness webinar: Detecting, reporting, and partnering for survivors Human trafficking: Closer to home than you think  

In this episode of The Egg Whisperer Show, I'm joined by Trudy McKanna, Senior Field Medical Director at GRAIL, to talk about a groundbreaking new test called Galleri®. This multi-cancer early detection test can identify signals of more than 50 different types of cancer through a simple blood draw, often before symptoms appear. For anyone focused on protecting their long-term health, identifying possible cancers early, and for those who have done treatment and may be concerned about future cancer risk, this technology could be life-changing. We talk about how the Galleri® test works, the science behind it, and what this means for cancer treatment and detection. Trudy also shares why early detection is so critical, how accurate the test is, and what healthcare providers and patients need to know about accessing this innovation. Read the full show notes on Dr. Aimee's site (with a transcript). In this episode, we cover: - What GRAIL's Galleri® test is and how it works - How early cancer detection offers more time and options for care, plus how it may help patients avoid chemo - Why the test could revolutionize preventative care and cancer treatment plans - What fertility specialists and patients should know about using Galleri® after Clomid usage - How GRAIL is working to expand access and education around early detection Find GRAIL's Galleri® test here: https://www.galleri.com/ Do you have questions about IVF? Click here to join Dr. Aimee for The IVF Class. The next live class call is on Monday, July 13, 2026, at 4 pm PST, where I'll explain IVF and Egg Freezing, and answer your questions live on Zoom. Other ways to connect with me: Visit my YouTube channel for more fertility tipsSubscribe to the newsletter to get updatesJoin Egg Whisperer SchoolRequest a Consultation with Dr. Aimee Dr. Aimee Eyvazzadeh is one of America's most well-known fertility doctors. Her success rate at baby-making gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.

Dr. Dan Ackerman and Dr. Reza Bavarsad Shahripour discuss the diagnostic performance of 4 major modalities: TCD, TTE, TEE, and cardiac CT in patients with embolic stroke of undetermined source.  Sho citation:  Read the related article in Neurology® Clinical Practice.     

Dr. Dan Ackerman talks with Dr. Reza Bavarsad Shahripour about the diagnostic performance of 4 major modalities: TCD, TTE, TEE, and cardiac CT in patients with embolic stroke of undetermined source.  Read the related article in Neurology® Clinical Practice.  Disclosures can be found at Neurology.org. 

As enterprises expand across multiple cloud environments, on-premise data centers, and dynamic AI workloads, traditional perimeter defenses and siloed cloud-native tools are no longer enough to secure the modern network. In this episode, Ashish sits down with Murali Rathinasamy, Senior Director of Product at Cisco, to break down the next evolution of network security: the Hybrid Mesh Firewall. Murali explains why relying solely on cloud-native firewalls can create visibility gaps, and how unified policy orchestration allows security teams to manage enforcement points seamlessly. He shares a real-world case study of how Multicloud Defense is used to eliminate manual route table configurations and achieve zero-downtime, blue-green upgrades. The conversation also tackles micro-segmentation. Murali breaks down why segmentation initiatives usually stall in "analysis paralysis" and provides a practical, agentless roadmap to reduce your attack surface "one bite at a time". Guest Socials -⁠⁠ ⁠⁠⁠Murali's LinkedinPodcast Twitter - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@CloudSecPod⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠If you want to watch videos of this LIVE STREAMED episode and past episodes - Check out our other Cloud Security Social Channels:-⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Cloud Security Podcast- Youtube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠- ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Cloud Security Newsletter ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠If you are interested in AI Security, you can check out our sister podcast -⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ AI Security Podcast⁠Questions(00:00) Introduction(01:40) Murali Rathinasamy's Background and Role at Cisco(02:30) What is a Hybrid Mesh Firewall?(04:30) Bridging the Skills Gap: NetSec vs. CNAPP/CSPM(06:45) Case Study: Royal College of Surgeons in Ireland (RCSI)(09:40) The Limits of Cloud-Native Firewalls in a Multicloud World(13:30) Securing AI Workloads and Managing the Agent Blast Radius(15:40) Why You Need Unified Policy Orchestration Across Firewall Vendors(17:40) Why Micro-segmentation Fails: Overcoming Analysis Paralysis(24:45) How to Implement Micro-segmentation "One Bite at a Time"(31:30) Detecting and Blocking Prompt Injections with Cisco AI Defense(33:30) Where Does the Hybrid Mesh Firewall Fit in the Tech Stack?

How do quantitative investors adapt when markets, technology and macro regimes are constantly changing? In this conversation, Alan Dunne sits down with George Patterson, CIO of PGIM Quant Solutions, to explore the evolution of systematic investing from the 1990s to today's AI driven landscape. They discuss regime detection, inflation risk, portfolio construction, machine learning, private markets, volatility overlays and the growing role of language models in investment research. George also shares insights from decades in quant investing, including lessons from Covid, the importance of model discipline and why communication skills matter as much as technical expertise.-----50 YEARS OF TREND FOLLOWING BOOK AND BEHIND-THE-SCENES VIDEO FOR ACCREDITED INVESTORS - CLICK HERE-----Follow Niels on Twitter, LinkedIn, YouTube or via the TTU website.IT's TRUE ? – most CIO's read 50+ books each year – get your FREE copy of the Ultimate Guide to the Best Investment Books ever written here.And you can get a free copy of my latest book “Ten Reasons to Add Trend Following to Your Portfolio” here.Learn more about the Trend Barometer here.Send your questions to info@toptradersunplugged.comAnd please share this episode with a like-minded friend and leave an honest Rating & Review on iTunes or Spotify so more people can discover the podcast.Follow Alan on Twitter.Follow George on LinkedIn.Episode TimeStamps: 00:00 - Introduction to George Patterson and his journey from physics to quantitative investing03:12 - Why multidisciplinary teams matter in modern quant investing04:13 - Inside PGIM Quant Solutions and the evolution of multi asset investing06:03 - How markets and macro investing have changed since the 1990s09:12 - The future of the 60/40 portfolio and institutional portfolio construction12:11 - Private markets, liquidity challenges and institutional investor concerns13:25 - Inflation, commodities and building modern inflation hedges19:33 - Detecting macro regimes using quantitative models23:26 - The hardest part of systematic investing: trusting the process27:00 - Covid, model failures and managing regime shifts in real time30:07 - Portfolio protection, options strategies and volatility overlays32:01 - How AI and large language models are transforming quantitative research40:02 - Fiscal risks, inflation concerns and the changing rate environment44:26 - Simplicity versus complexity in quantitative model design48:05 - Why markets evolve faster today and how models must adapt51:08 - Retail investors, meme stocks and market distortions53:33 - Emerging markets and where long term opportunities may exist55:08 - The future of quant investing and the limits of AI hype57:10 - George Patterson's career advice for aspiring quantsCopyright © 2025 – CMC AG – All Rights Reserved----PLUS: Whenever you're ready... here are 3 ways I can help you in your investment Journey:1. eBooks that cover key topics that you need to know about In my eBooks, I put together some key discoveries and things I have learnt during the more than 3 decades I have worked in the Trend Following industry, which I hope you will find useful. Click Here2. Daily Trend Barometer and Market Score One of the things I'm really proud of, is the fact that I have managed to published the Trend Barometer and Market Score each day for more than a decade...as these tools are really good at describing the environment for trend following managers as well as giving insights into the general positioning of a trend following strategy! Click Here3. Other Resources that can help youAnd if you are hungry for more useful resources from the trend following world...check out some precious resources that I have found over the years to be really valuable. Click HerePrivacy PolicyDisclaimer

CardioNerds (Dr. Billy-Joe Mullinax, Dr. Dinu Balanescu, and Dr. Jane Ehret) discuss risk stratification in acute pulmonary embolism with Dr. Stavros Konstantinides, Chair of the 2019 ESC Pulmonary Embolism Guidelines. Using a real-world case, this episode explores how modern PE care has moved beyond “massive” and “submassive” labels toward a dynamic, physiology-based approach. The discussion highlights the limitations of static risk scores, the importance of right ventricular dysfunction and biomarkers, and why normotension does not imply stability. Special emphasis is placed on intermediate-high risk PE, early identification of impending hemodynamic collapse, and the role of lactate, serial reassessment, and PERT teams in guiding escalation of care. Audio editing by CardioNerds intern, Joshua Khorsandi.The 2026 American multi-society PE guidelines were published after this episode was recorded. Dr. Dinu Balanescu and Dr. Billy-Joe Mullinax are Co-chairs for the CardioNerds PE Series, developed in collaboration with the PERT Consortium.   Enjoy this Circulation 2022 Paths to Discovery article to learn about the CardioNerds story, mission, and values. CardioNerds Pulmonary Embolism PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls Stable blood pressure does not mean low risk in PEHypotension is a late finding. Patients may have severe RV failure, hypoxia, and tissue hypoperfusion while remaining normotensive — a key concept behind “normotensive shock.” Risk stratification in PE must be dynamic, not staticLegacy scores like PESI and Bova provide a snapshot and predict 30-day mortality, but they do not capture short-term trajectory or impending hemodynamic collapse. Intermediate-high risk PE is a dangerous and heterogeneous groupPatients with RV dysfunction, positive biomarkers, tachycardia, hypoxemia, and elevated lactate may have in-hospital mortality approaching 15%, rivaling STEMI. Lactate is a critical but underutilized marker in PEElevated lactate reflects tissue hypoxia and early circulatory failure and may identify patients at risk for collapse before blood pressure declines. PERT enables physiology-driven, patient-centered PE carePERT teams operationalize continuous reassessment, integrate imaging, labs, and clinical trajectory, and allow timely escalation — shifting PE management from rigid categories to real-time decision-making. Notes Drafted by Dr. Jane Ehret. 1. What is the contemporary framework for risk stratification in acute pulmonary embolism? Modern PE risk stratification prioritizes hemodynamics and right ventricular (RV) function rather than clot burden. The 2019 ESC Guidelines classify PE into high risk, intermediate risk (low vs high), and low risk, based on: Hemodynamic status, RV dysfunction on imaging, and Cardiac biomarkers. This framework emphasizes early mortality risk but requires clinical context to guide escalation decisions. 2. Why is normotension insufficient to define “stability” in PE? Blood pressure is a late marker of circulatory failure in PE. Patients can maintain normal BP through Tachycardia, Increased sympathetic tone, and RV compensation. Many patients with preserved BP may already have shock physiology, including hypoxemia, elevated lactate, and RV failure — sometimes referred to as “normotensive shock.” 3. How should intermediate-risk PE be conceptualized clinically? Intermediate-risk PE is heterogeneous, ranging from patients who do well on anticoagulation to those who deteriorate rapidly. Intermediate-high risk PE is defined by RV dysfunction on imaging and positive cardiac biomarkers. Clinical features such as tachycardia, increasing oxygen requirement, and elevated lactate identify patients at highest risk within this group. 4. What are the strengths and limitations of commonly used PE risk scores? Legacy scores are useful for initial risk categorization but are static and limited in predicting short-term deterioration. Most scores were developed to predict mortality or complications at fixed time points rather than dynamic clinical trajectory. 5. What are the commonly used risk scores and clinical tools in PE, and what is each designed to predict? ESC Risk Stratification Algorithm: Identifies high-risk PE by hemodynamics. Uses PESI or sPESI in normotensive patients to distinguish low-risk from non–low-risk PE. Uses RV dysfunction and biomarkers to differentiate intermediate-low from intermediate-high risk. Forms the basis of many institutional PE pathways. PESI and sPESI: Validated to predict 30-day mortality. Widely used to identify low-risk patients appropriate for outpatient management. Heavily influenced by age and comorbidities. Bova Score: Predicts 30-day PE-related complications in normotensive patients. Composite PE Shock Score (CPES): Predicts normotensive shock in hemodynamically stable PE patients. Pulmonary Embolism Progression (PEP) Score: Predicts progression from intermediate-risk to high-risk PE within 72 hours of diagnosis. PE Short-term Clinical Outcomes Risk Estimation (PE-SCORE): Predicts clinical deterioration or death within 5 days of PE diagnosis. Hestia Criteria: Identifies low-risk PE patients safe for outpatient treatment. Wells' Criteria and Revised Geneva Score: Determine pretest probability for diagnostic triage. PERC Score: Rules out PE in very low-risk patients. 6. What is the role of biomarkers in PE risk stratification? Troponin and natriuretic peptides reflect RV myocardial injury and strain. Current guidelines treat biomarkers as binary (positive vs negative), despite risk being continuous. Biomarkers are most helpful for: Initial risk classification. They are less useful for: Short-interval monitoring and Detecting rapid clinical deterioration. 7. Why is lactate an important physiologic marker in PE? Lactate reflects global tissue hypoxia and impaired perfusion. Elevated lactate may identify patients with: Early circulatory failure and Increased risk of imminent hemodynamic collapse. Lactate is not currently included in ESC risk algorithms but may add important prognostic information in intermediate-risk patients. 8. How does trajectory influence decision-making in PE management? Risk stratification should be viewed as a dynamic process, not a one-time label. Worsening clinical trajectory may include: Rising heart rate, Increasing oxygen needs, Rising lactate, and Progressive RV dysfunction. Serial reassessment is essential for timely escalation of care. 9. What role do Pulmonary Embolism Response Teams (PERT) play in risk stratification? PERT facilitates: Multidisciplinary decision-making and Integration of imaging, biomarkers, and clinical physiology. PERT is most valuable for: Intermediate-risk and high-risk PE and Patients with complex comorbidities or uncertain trajectory. PERT enables a shift from category-based to physiology-driven PE care. References 1. Konstantinides SV, Meyer G, Becattini C, et al. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS): The Task Force for the diagnosis and management of acute pulmonary embolism of the European Society of Cardiology (ESC). Eur Respir J. 2019;54(3):1901647. Published 2019 Oct 9. doi:10.1183/13993003.01647-2019 2. Leidi A, Bex S, Righini M, Berner A, Grosgurin O, Marti C. Risk Stratification in Patients with Acute Pulmonary Embolism: Current Evidence and Perspectives. J Clin Med. 2022;11(9):2533. Published 2022 Apr 30. doi:10.3390/jcm11092533 3. Choi WH, Kwon SU, Jwa YJ, et al. The pulmonary embolism severity index in predicting the prognosis of patients with pulmonary embolism. Korean J Intern Med. 2009;24(2):123-127. doi:10.3904/kjim.2009.24.2.123 4. Jiménez D, Aujesky D, Moores L, et al. Simplification of the pulmonary embolism severity index for prognostication in patients with acute symptomatic pulmonary embolism. Arch Intern Med. 2010;170(15):1383-1389. doi:10.1001/archinternmed.2010.199 5. Chen X, Shao X, Zhang Y, et al. Assessment of the Bova score for risk stratification of acute normotensive pulmonary embolism: A systematic review and meta-analysis. Thromb Res. 2020;193:99-106. doi:10.1016/j.thromres.2020.05.047 6. Zhang RS, Yuriditsky E, Zhang P, et al. Composite Pulmonary Embolism Shock Score and Risk of Adverse Outcomes in Patients With Pulmonary Embolism. Circ Cardiovasc Interv. 2024;17(8):e014088. doi:10.1161/CIRCINTERVENTIONS.124.014088 7. Zhang RS, Alam U, Sharp ASP, et al. Validating the Composite Pulmonary Embolism Shock Score for Predicting Normotensive Shock in Intermediate-Risk Pulmonary Embolism. Circ Cardiovasc Interv. 2024;17(2):e013399. doi:10.1161/CIRCINTERVENTIONS.123.013399 8. Ehret J, Wakefield D, Badlam J, Antkowiak M, Erdreich B. Development of the Pulmonary Embolism Progression (PEP) score for predicting short-term clinical deterioration in intermediate-risk pulmonary embolism: a single-center retrospective study. J Thromb Thrombolysis. 2025;58(2):243-253. doi:10.1007/s11239-024-03051-5 9. Weekes AJ, Raper JD, Lupez K, et al. Development and validation of a prognostic tool: Pulmonary embolism short-term clinical outcomes risk estimation (PE-SCORE). PLoS One. 2021;16(11):e0260036. Published 2021 Nov 18. doi:10.1371/journal.pone.0260036 10. Zondag W, Hiddinga BI, Crobach MJ, et al. Hestia criteria can discriminate high- from low-risk patients with pulmonary embolism. Eur Respir J. 2013;41(3):588-592. doi:10.1183/09031936.00030412 11. Wells PS, Anderson DR, Rodger M, et al. Excluding pulmonary embolism at the bedside without diagnostic imaging: management of patients with suspected pulmonary embolism presenting to the emergency department by using a simple clinical model and d-dimer. Ann Intern Med. 2001;135(2):98-107. doi:10.7326/0003-4819-135-2-200107170-00010 12. Wolf SJ, McCubbin TR, Feldhaus KM, Faragher JP, Adcock DM. Prospective validation of Wells Criteria in the evaluation of patients with suspected pulmonary embolism. Ann Emerg Med. 2004;44(5):503-510. doi:10.1016/j.annemergmed.2004.04.002 13. Le Gal G, Righini M, Roy PM, et al. Prediction of pulmonary embolism in the emergency department: the revised Geneva score. Ann Intern Med. 2006;144(3):165-171. doi:10.7326/0003-4819-144-3-200602070-00004 14. Kline JA, Mitchell AM, Kabrhel C, Richman PB, Courtney DM. Clinical criteria to prevent unnecessary diagnostic testing in emergency department patients with suspected pulmonary embolism. J Thromb Haemost. 2004;2(8):1247-1255. doi:10.1111/j.1538-7836.2004.00790.x 15. Kline JA, Courtney DM, Kabrhel C, et al. Prospective multicenter evaluation of the pulmonary embolism rule-out criteria. J Thromb Haemost. 2008;6(5):772-780. doi:10.1111/j.1538-7836.2008.02944.x

Retired Secret Service Brad Beeler goes behind the badge to reveal what it truly takes to protect the most powerful person on Earth, and what 25 years of high-stakes federal service teaches you about human nature, sacrifice, and the truth!!

Patricio Gallardo discusses the mysteries of dark matter and dark energy. He details future efforts to calibrate telescopes for detecting the "Axion" particle to understand the composition of the missing universe. (8/16)1920 SC