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Your latest update from Spectrum, the leading source of news and expert opinion on autism research.

Spectrum

New York, N.Y.


    • Jul 11, 2025 LATEST EPISODE
    • weekdays NEW EPISODES
    • 6m AVG DURATION
    • 1,458 EPISODES


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    Latest episodes from Spectrum Autism Research

    Neuropeptides reprogram social roles in leafcutter ants

    Play Episode Listen Later Jul 11, 2025 6:50


    The mechanisms that control the labor roles of ants may also be conserved in naked mole rats, a new study shows.

    Nature retracts paper on novel brain cell type against authors' wishes

    Play Episode Listen Later Jul 9, 2025 4:23


    A 2022 paper was retracted after an independent team of researchers reanalyzed the data and questioned its validity.

    Drosophila, like vertebrates, filter sensory information during sleep

    Play Episode Listen Later Jul 8, 2025 5:06


    Predictive sensory processing in sleeping Drosophila echoes vertebrate research, establishing an evolutionarily conserved neural signature of sleep.

    Neuroscience's open-data revolution is just getting started

    Play Episode Listen Later Jul 7, 2025 7:48


    Data reuse represents an opportunity to accelerate the pace of science, reduce costs and increase the value of our collective research investments. New tools that make open data easier to use—and new pressures, including funding cuts—may increase uptake.

    Machine learning spots neural progenitors in adult human brains

    Play Episode Listen Later Jul 3, 2025 6:31


    But the finding has not settled the long-standing debate over the existence and extent of neurogenesis during adulthood, says Yale University neuroscientist Juan Arellano.

    Astrocytes sense neuromodulators to orchestrate neuronal activity and shape behavior

    Play Episode Listen Later Jun 27, 2025 9:29


    Astrocytes serve as crucial mediators of neuromodulatory processes previously attributed to direct communication between neurons, four new studies show.

    Spatial learning circuitry fluctuates in step with estrous cycle in mice

    Play Episode Listen Later Jun 25, 2025 5:41


    Cyclic shifts in estradiol levels coincide with changes in dendritic spine density and the activity of place cells in the CA1 region of the hippocampus, a new study shows.

    Expanded view of hippocampal function comes into focus

    Play Episode Listen Later Jun 24, 2025 11:14


    After decades of debate, the region's role is being rewritten. Rather than using sensory input to simply log key points in time and space, the hippocampus may serve to contextualize our experiences and memories—and ultimately make predictions about the future.

    Many students want to learn to use artificial intelligence responsibly. But their professors are struggling to meet that need.

    Play Episode Listen Later Jun 23, 2025 8:23


    Effectively teaching students how to employ AI in their writing assignments requires clear guidelines—and detailed, case-specific examples.

    The big idea with Diego Bohórquez

    Play Episode Listen Later Jun 20, 2025 13:42


    His theories around the neuropod have challenged the boundaries of classic ideas regarding gut-brain communication.

    Genetic background steers PTEN syndrome traits

    Play Episode Listen Later Jun 19, 2025 5:21


    People with the syndrome, caused by variants in the gene PTEN, often have autism or cancer, or both, but it depends on the genetic diversity encoded in the components of distinct cell signaling pathways, according to a new study.

    Star-responsive neurons steer moths' long-distance migration

    Play Episode Listen Later Jun 18, 2025 5:15


    Cells in the bogong moth brain respond to astral landmarks to orient the insects in the direction they need to go.

    This paper changed my life: Bradley Dickerson on how a 1940s fly neuroanatomy paper influences his research to this day

    Play Episode Listen Later Jun 17, 2025 5:25


    This classic paper by zoologist John Pringle describes the haltere—a small structure in flies that plays a crucial role in flight control. It taught me to think about circuits and behavior as greater than the sum of their parts.

    Gazing at a location from afar activates place cells in chickadees

    Play Episode Listen Later Jun 13, 2025 5:53


    The results help explain how the hippocampus can recall information about a place without an animal physically revisiting it.

    Some dopamine neurons signal default behaviors to reinforce habits

    Play Episode Listen Later Jun 11, 2025 4:54


    Movement-sensing neurons that target the striatum influence a mouse's choice of action by favoring routine.

    On the importance of reading (just not too much)

    Play Episode Listen Later Jun 9, 2025 8:43


    The real fun of being a neuroscientist, and maybe the key to asking and answering new questions, is to think big and take intellectual risks.

    How developing neurons simplify their search for a synaptic mate

    Play Episode Listen Later Jun 6, 2025 6:52


    Streamlining the problem from 3D to 1D eases the expedition—a strategy the study investigators deployed to rewire an olfactory circuit in flies.

    'Understudied secret' in brain dampens nicotine drive in mice

    Play Episode Listen Later Jun 4, 2025 4:31


    The interpeduncular nucleus produces an aversion to nicotine, even at low doses, and helps moderate how rewarding mice find the drug.

    Rethinking how neural activity sculpts critical periods

    Play Episode Listen Later Jun 3, 2025 6:20


    New findings on the role of neural activity in developing circuits are challenging our prior notions about the rules that govern critical periods.

    To understand the brain as a network organ, we must image cortical layers

    Play Episode Listen Later Jun 2, 2025 6:38


    Human neuroscience research has largely overlooked this spatial scale—which bridges cells and brain areas. But new advances in functional MRI technology are changing that.

    Amina Abubakar translates autism research and care for Kenya

    Play Episode Listen Later May 29, 2025 8:04


    First an educator and now an internationally recognized researcher, the Kenyan psychologist is changing autism science and services in sub-Saharan Africa.

    Learning in living mice defies classic synaptic plasticity rule

    Play Episode Listen Later May 28, 2025 5:42


    Donald Hebb's theory—memorably summarized as “cells that fire together, wire together”—does not explain the shifting hippocampal connections in mice learning to navigate a virtual environment, according to a new study.

    Cephalopods, vision's next frontier

    Play Episode Listen Later May 27, 2025 14:23


    For decades, scientists have been teased by the strange but inaccessible cephalopod visual system. Now, thanks to a technological breakthrough from a lab in Oregon, data are finally coming straight from the octopus brain.

    Escaping groupthink: What animals' behavioral quirks reveal about the brain

    Play Episode Listen Later May 23, 2025 10:05


    Neuroscientists have long ignored the variability in animals' behavioral responses in favor of studying differences across groups. But work on the brain differences that underlie that variability is beginning to pay off.

    Immune cells block pain in female mice only

    Play Episode Listen Later May 22, 2025 5:30


    Regulatory T cells in the spinal meninges release endogenous opioids in a sex-specific manner, new work shows.

    The BabyLM Challenge: In search of more efficient learning algorithms, researchers look to infants

    Play Episode Listen Later May 19, 2025 8:31


    A competition that trains language models on relatively small datasets of words, closer in size to what a child hears up to age 13, seeks solutions to some of the major challenges of today's large language models.

    Reporter's notebook: Highlights from INSAR 2025

    Play Episode Listen Later May 15, 2025 6:12


    The annual meeting brought autism researchers, advocates and clinicians to Seattle to discuss the latest research, including attempts to define subgroups, a potential new CHD8 macaque model and life expectancy gaps.

    NIDA shutters diversity fellowship program, axes active awards

    Play Episode Listen Later May 14, 2025 4:53


    It's unclear if the cancellation at the U.S. National Institute on Drug Abuse extends to the fellowships awarded by other institutes within the National Institutes of Health.

    'We still exist': How four neuroscience advocacy groups are navigating federal DEI funding cuts

    Play Episode Listen Later May 14, 2025 17:57


    Trainees from underrepresented backgrounds are losing pillars of support in the current funding climate. Grassroots mentorship organizations are stepping in to continue championing early-career researchers.

    This paper changed my life: Marino Pagan recalls a decision-making study from four titans in the field

    Play Episode Listen Later May 13, 2025 6:49


    Valerio Mante and David Sussillo, along with their mentors Krishna Shenoy and Bill Newsome, revealed the complexity of neural population dynamics and the power of recurrent neural networks.

    Exclusive: Recruitment issues jeopardize ambitious plan for human brain atlas

    Play Episode Listen Later May 9, 2025 6:28


    A lack of six new brain donors may stop the project from meeting its goal to pair molecular and cellular data with the functional organization of the cortex.

    How pragmatism and passion drive Fred Volkmar-even after retirement

    Play Episode Listen Later May 8, 2025 10:15


    Whether looking back at his career highlights or forward to his latest projects, the psychiatrist is committed to supporting autistic people at every age.

    Sleep doesn't just consolidate memories; it actively shapes them

    Play Episode Listen Later May 6, 2025 5:52


    The rapid eye movement (REM) phase preserves newly acquired memories, but deeper non-REM sleep helps to adapt and update them, according to “heroic” day-long electrode recordings in rats.

    Thinking about thinking: AI offers theoretical insights into human memory

    Play Episode Listen Later May 5, 2025 8:13


    We need a new conceptual framework for understanding cognitive functions—particularly how globally distributed brain states are formed and maintained for hours.

    Mitochondrial 'landscape' shifts across human brain

    Play Episode Listen Later Apr 25, 2025 6:41


    Evolutionarily newer regions sport mitochondria with a higher capacity for energy production than older regions, according to the first detailed map of the organelles in a tissue slice, adding to mounting evidence that the brain features a metabolic gradient.

    This paper changed my life: Shane Liddelow on two papers that upended astrocyte research

    Play Episode Listen Later Apr 23, 2025 6:37


    A game-changing cell culture method developed in Ben Barres' lab completely transformed the way we study astrocytes and helped me build a career studying their reactive substates.

    What birds can teach us about the 'biological truth' of sex

    Play Episode Listen Later Apr 22, 2025 8:28


    Part of our job as educators is to give students a deeper understanding of the true diversity of sex and gender in the natural world.

    Noninvasive technologies can map and target human brain with unprecedented precision

    Play Episode Listen Later Apr 21, 2025 9:02


    But to fully grasp the tools' potential, we need to better understand how electric and magnetic fields interact with the brain.

    During decision-making, brain shows multiple distinct subtypes of activity

    Play Episode Listen Later Apr 18, 2025 6:46


    Person-to-person variability in brain activity might represent meaningful differences in cognitive processes, rather than random noise.

    Smell studies often use unnaturally high odor concentrations, analysis reveals

    Play Episode Listen Later Apr 16, 2025 8:24


    It's time to fashion olfactory neuroscience stimuli based on odor concentrations in the wild, say study investigators Elizabeth Hong and Matt Wachowiak.

    Functional MRI can do more than you think

    Play Episode Listen Later Apr 14, 2025 8:03


    Recent technological advances provide a range of new and different information about brain physiology. But taking full advantage of these gains depends on collaboration between engineers and neuroscientists.

    U.S. human data repositories 'under review' for gender identity descriptors

    Play Episode Listen Later Apr 9, 2025 3:49


    Researchers associated with the repositories received an email from the U.S. National Institutes of Health in March noting that they must comply with a 20 January executive order from President Trump that recognizes only two sexes: male and female.

    Inhibitory cells work in concert to orchestrate neuronal activity in mouse brain

    Play Episode Listen Later Apr 9, 2025 6:16


    A cubic millimeter of brain tissue, meticulously sectioned, stained and scrutinized over the past seven years, reveals in stunning detail the role of inhibitory interneurons in brain structure and function.

    Exclusive: NIH nixes funds for several pre- and postdoctoral training programs

    Play Episode Listen Later Apr 8, 2025 8:50


    Many of the axed grants support scientists from underrepresented communities.

    To make a meaningful contribution to neuroscience, fMRI must break out of its silo

    Play Episode Listen Later Apr 8, 2025 8:03


    We need to develop research programs that link phenomena across levels, from genes and molecules to cells, circuits, networks and behavior.

    In vivo veritas: Xenotransplantation can help us study the development and function of human neurons in a living brain

    Play Episode Listen Later Apr 7, 2025 9:11


    Transplanted cells offer insight into human-specific properties, such as a lengthy cortical development and sensitivity to neurodevelopmental and neurodegenerative disease.

    Keep sex as a biological variable: Don't let NIH upheaval turn back the clock on scientific rigor

    Play Episode Listen Later Mar 25, 2025 7:28


    Even in the absence of any formal instruction to do so, we should continue to hold our ourselves and our neuroscience colleagues accountable for SABV practices.

    Single-neuron recordings are helping to unravel complexities of human cognition

    Play Episode Listen Later Mar 14, 2025 9:30


    As this work begins to bear fruit, researchers “are becoming less afraid to ask very difficult questions that you can uniquely ask in people.”

    U.S. BRAIN Initiative set to lose $81 million this year

    Play Episode Listen Later Mar 11, 2025 3:26


    A government spending bill, which was approved today by the House of Representatives and heads next to a Senate vote, allocates 20 percent less funding for the program than last year.

    New tools help make neuroimaging accessible to more researchers

    Play Episode Listen Later Mar 5, 2025 6:04


    A lack of programming experience can derail experimental aspirations. But custom software packages, web-based applications and video tutorials make functional MRI concepts easier to grasp.

    About-faces in U.S. federal science funding put neuroscientists on edge

    Play Episode Listen Later Feb 12, 2025 6:16


    “It's hard to know what's real,” says neuroscientist Josh Dubnau after a dizzying week in which diversity-related grant applications were pulled from study sections only to be reinstated five days later, among other reversals.

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