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Your latest update from Spectrum, the leading source of news and expert opinion on autism research.

Spectrum

New York, N.Y.


    • Jun 13, 2025 LATEST EPISODE
    • weekdays NEW EPISODES
    • 6m AVG DURATION
    • 1,445 EPISODES


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    Latest episodes from Spectrum Autism Research

    Gazing at a location from afar activates place cells in chickadees

    Play Episode Listen Later Jun 13, 2025 5:53


    The results help explain how the hippocampus can recall information about a place without an animal physically revisiting it.

    Some dopamine neurons signal default behaviors to reinforce habits

    Play Episode Listen Later Jun 11, 2025 4:54


    Movement-sensing neurons that target the striatum influence a mouse's choice of action by favoring routine.

    On the importance of reading (just not too much)

    Play Episode Listen Later Jun 9, 2025 8:43


    The real fun of being a neuroscientist, and maybe the key to asking and answering new questions, is to think big and take intellectual risks.

    How developing neurons simplify their search for a synaptic mate

    Play Episode Listen Later Jun 6, 2025 6:52


    Streamlining the problem from 3D to 1D eases the expedition—a strategy the study investigators deployed to rewire an olfactory circuit in flies.

    'Understudied secret' in brain dampens nicotine drive in mice

    Play Episode Listen Later Jun 4, 2025 4:31


    The interpeduncular nucleus produces an aversion to nicotine, even at low doses, and helps moderate how rewarding mice find the drug.

    Rethinking how neural activity sculpts critical periods

    Play Episode Listen Later Jun 3, 2025 6:20


    New findings on the role of neural activity in developing circuits are challenging our prior notions about the rules that govern critical periods.

    To understand the brain as a network organ, we must image cortical layers

    Play Episode Listen Later Jun 2, 2025 6:38


    Human neuroscience research has largely overlooked this spatial scale—which bridges cells and brain areas. But new advances in functional MRI technology are changing that.

    Amina Abubakar translates autism research and care for Kenya

    Play Episode Listen Later May 29, 2025 8:04


    First an educator and now an internationally recognized researcher, the Kenyan psychologist is changing autism science and services in sub-Saharan Africa.

    Learning in living mice defies classic synaptic plasticity rule

    Play Episode Listen Later May 28, 2025 5:42


    Donald Hebb's theory—memorably summarized as “cells that fire together, wire together”—does not explain the shifting hippocampal connections in mice learning to navigate a virtual environment, according to a new study.

    Cephalopods, vision's next frontier

    Play Episode Listen Later May 27, 2025 14:23


    For decades, scientists have been teased by the strange but inaccessible cephalopod visual system. Now, thanks to a technological breakthrough from a lab in Oregon, data are finally coming straight from the octopus brain.

    Escaping groupthink: What animals' behavioral quirks reveal about the brain

    Play Episode Listen Later May 23, 2025 10:05


    Neuroscientists have long ignored the variability in animals' behavioral responses in favor of studying differences across groups. But work on the brain differences that underlie that variability is beginning to pay off.

    Immune cells block pain in female mice only

    Play Episode Listen Later May 22, 2025 5:30


    Regulatory T cells in the spinal meninges release endogenous opioids in a sex-specific manner, new work shows.

    The BabyLM Challenge: In search of more efficient learning algorithms, researchers look to infants

    Play Episode Listen Later May 19, 2025 8:31


    A competition that trains language models on relatively small datasets of words, closer in size to what a child hears up to age 13, seeks solutions to some of the major challenges of today's large language models.

    Reporter's notebook: Highlights from INSAR 2025

    Play Episode Listen Later May 15, 2025 6:12


    The annual meeting brought autism researchers, advocates and clinicians to Seattle to discuss the latest research, including attempts to define subgroups, a potential new CHD8 macaque model and life expectancy gaps.

    NIDA shutters diversity fellowship program, axes active awards

    Play Episode Listen Later May 14, 2025 4:53


    It's unclear if the cancellation at the U.S. National Institute on Drug Abuse extends to the fellowships awarded by other institutes within the National Institutes of Health.

    'We still exist': How four neuroscience advocacy groups are navigating federal DEI funding cuts

    Play Episode Listen Later May 14, 2025 17:57


    Trainees from underrepresented backgrounds are losing pillars of support in the current funding climate. Grassroots mentorship organizations are stepping in to continue championing early-career researchers.

    This paper changed my life: Marino Pagan recalls a decision-making study from four titans in the field

    Play Episode Listen Later May 13, 2025 6:49


    Valerio Mante and David Sussillo, along with their mentors Krishna Shenoy and Bill Newsome, revealed the complexity of neural population dynamics and the power of recurrent neural networks.

    Exclusive: Recruitment issues jeopardize ambitious plan for human brain atlas

    Play Episode Listen Later May 9, 2025 6:28


    A lack of six new brain donors may stop the project from meeting its goal to pair molecular and cellular data with the functional organization of the cortex.

    How pragmatism and passion drive Fred Volkmar-even after retirement

    Play Episode Listen Later May 8, 2025 10:15


    Whether looking back at his career highlights or forward to his latest projects, the psychiatrist is committed to supporting autistic people at every age.

    Sleep doesn't just consolidate memories; it actively shapes them

    Play Episode Listen Later May 6, 2025 5:52


    The rapid eye movement (REM) phase preserves newly acquired memories, but deeper non-REM sleep helps to adapt and update them, according to “heroic” day-long electrode recordings in rats.

    Thinking about thinking: AI offers theoretical insights into human memory

    Play Episode Listen Later May 5, 2025 8:13


    We need a new conceptual framework for understanding cognitive functions—particularly how globally distributed brain states are formed and maintained for hours.

    Mitochondrial 'landscape' shifts across human brain

    Play Episode Listen Later Apr 25, 2025 6:41


    Evolutionarily newer regions sport mitochondria with a higher capacity for energy production than older regions, according to the first detailed map of the organelles in a tissue slice, adding to mounting evidence that the brain features a metabolic gradient.

    This paper changed my life: Shane Liddelow on two papers that upended astrocyte research

    Play Episode Listen Later Apr 23, 2025 6:37


    A game-changing cell culture method developed in Ben Barres' lab completely transformed the way we study astrocytes and helped me build a career studying their reactive substates.

    What birds can teach us about the 'biological truth' of sex

    Play Episode Listen Later Apr 22, 2025 8:28


    Part of our job as educators is to give students a deeper understanding of the true diversity of sex and gender in the natural world.

    Noninvasive technologies can map and target human brain with unprecedented precision

    Play Episode Listen Later Apr 21, 2025 9:02


    But to fully grasp the tools' potential, we need to better understand how electric and magnetic fields interact with the brain.

    During decision-making, brain shows multiple distinct subtypes of activity

    Play Episode Listen Later Apr 18, 2025 6:46


    Person-to-person variability in brain activity might represent meaningful differences in cognitive processes, rather than random noise.

    Smell studies often use unnaturally high odor concentrations, analysis reveals

    Play Episode Listen Later Apr 16, 2025 8:24


    It's time to fashion olfactory neuroscience stimuli based on odor concentrations in the wild, say study investigators Elizabeth Hong and Matt Wachowiak.

    Functional MRI can do more than you think

    Play Episode Listen Later Apr 14, 2025 8:03


    Recent technological advances provide a range of new and different information about brain physiology. But taking full advantage of these gains depends on collaboration between engineers and neuroscientists.

    U.S. human data repositories 'under review' for gender identity descriptors

    Play Episode Listen Later Apr 9, 2025 3:49


    Researchers associated with the repositories received an email from the U.S. National Institutes of Health in March noting that they must comply with a 20 January executive order from President Trump that recognizes only two sexes: male and female.

    Inhibitory cells work in concert to orchestrate neuronal activity in mouse brain

    Play Episode Listen Later Apr 9, 2025 6:16


    A cubic millimeter of brain tissue, meticulously sectioned, stained and scrutinized over the past seven years, reveals in stunning detail the role of inhibitory interneurons in brain structure and function.

    Exclusive: NIH nixes funds for several pre- and postdoctoral training programs

    Play Episode Listen Later Apr 8, 2025 8:50


    Many of the axed grants support scientists from underrepresented communities.

    To make a meaningful contribution to neuroscience, fMRI must break out of its silo

    Play Episode Listen Later Apr 8, 2025 8:03


    We need to develop research programs that link phenomena across levels, from genes and molecules to cells, circuits, networks and behavior.

    In vivo veritas: Xenotransplantation can help us study the development and function of human neurons in a living brain

    Play Episode Listen Later Apr 7, 2025 9:11


    Transplanted cells offer insight into human-specific properties, such as a lengthy cortical development and sensitivity to neurodevelopmental and neurodegenerative disease.

    Keep sex as a biological variable: Don't let NIH upheaval turn back the clock on scientific rigor

    Play Episode Listen Later Mar 25, 2025 7:28


    Even in the absence of any formal instruction to do so, we should continue to hold our ourselves and our neuroscience colleagues accountable for SABV practices.

    Single-neuron recordings are helping to unravel complexities of human cognition

    Play Episode Listen Later Mar 14, 2025 9:30


    As this work begins to bear fruit, researchers “are becoming less afraid to ask very difficult questions that you can uniquely ask in people.”

    U.S. BRAIN Initiative set to lose $81 million this year

    Play Episode Listen Later Mar 11, 2025 3:26


    A government spending bill, which was approved today by the House of Representatives and heads next to a Senate vote, allocates 20 percent less funding for the program than last year.

    New tools help make neuroimaging accessible to more researchers

    Play Episode Listen Later Mar 5, 2025 6:04


    A lack of programming experience can derail experimental aspirations. But custom software packages, web-based applications and video tutorials make functional MRI concepts easier to grasp.

    About-faces in U.S. federal science funding put neuroscientists on edge

    Play Episode Listen Later Feb 12, 2025 6:16


    “It's hard to know what's real,” says neuroscientist Josh Dubnau after a dizzying week in which diversity-related grant applications were pulled from study sections only to be reinstated five days later, among other reversals.

    Age-related brain changes in mice strike hypothalamus 'hot spot'

    Play Episode Listen Later Jan 16, 2025 5:43


    Neuronal and non-neuronal cells throughout the brain also express genes—particularly those related to neuronal structure and immune function—differently in aged mice, according to a new atlas.

    Males and females show different patterns of risk for brain-based conditions. Ignoring these differences does us all a disservice.

    Play Episode Listen Later Dec 18, 2024 9:04


    Although studying sex differences in the brain is complex, technically awkward and socioculturally loaded, it is absolutely essential.

    Immune cell interlopers breach-and repair-brain barrier in mice

    Play Episode Listen Later Nov 22, 2024 6:05


    The choroid plexus, the protective network of blood vessels and epithelial cells that line the brain's ventricles, recruits neutrophils and macrophages during inflammation, a new study shows.

    NeuroAI: A field born from the symbiosis between neuroscience, AI

    Play Episode Listen Later Nov 15, 2024 7:22


    As the history of this nascent discipline reveals, neuroscience has inspired advances in artificial intelligence, and AI has provided a testing ground for models in neuroscience, accelerating progress in both fields.

    Timing tweak turns trashed fMRI scans into treasure

    Play Episode Listen Later Oct 30, 2024 5:53


    Leveraging start-up “dummy scans,” which are typically discarded in imaging analyses, can shorten an experiment's length and make data collection more efficient, a new study reveals.

    Brains, biases and amyloid beta: Why the female brain deserves a closer look in Alzheimer's research

    Play Episode Listen Later Oct 25, 2024 8:04


    New results suggest the disease progresses differently in women, but we need more basic science to unpack the mechanisms involved.

    This paper changed my life: 'Spontaneous cortical activity reveals hallmarks of an optimal internal model of the environment,' from the Fiser Lab

    Play Episode Listen Later Oct 18, 2024 5:33


    Fiser's work taught me how to think about grounding computational models in biologically plausible implementations.

    The S-index Challenge: Develop a metric to quantify data-sharing success

    Play Episode Listen Later Oct 10, 2024 5:43


    The NIH-sponsored effort aims to help incentivize scientists to share data. But many barriers to the widespread adoption of useful data-sharing remain.

    A scientific fraud. An investigation. A lab in recovery.

    Play Episode Listen Later Oct 8, 2024 27:16


    Science is built on trust. What happens when someone destroys it?

    Repeat scans reveal brain changes that precede childbirth

    Play Episode Listen Later Oct 1, 2024 8:54


    A detailed look at a “pregnant brain” highlights a need to investigate the neural alterations that occur during a transition experienced by nearly 140 million people worldwide each year.

    Reconstructing dopamine's link to reward

    Play Episode Listen Later Sep 25, 2024 19:37


    The field is grappling with whether to modify the long-standing theory of reward prediction error—or abandon it entirely.

    In updated U.S. autism bill, Congress calls for funding boost, expanded scope

    Play Episode Listen Later Sep 10, 2024 5:35


    The current Autism CARES Act sunsets in late September.

    In updated U.S. autism bill, Congress calls for funding boost, expanded scope

    Play Episode Listen Later Sep 10, 2024 5:35


    The current Autism CARES Act sunsets in late September.

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