Podcasts about derived

Okay, sweet one, let's talk about the grand lie of having a purpose. Because hasn't everyone, at some point, stared into their organic kale salad and wondered, "WHY am I here?"Really, isn't that THE question? We're all chasing that deeper something, the elusive unicorn of purpose, because, well, we think it equals happiness. Glitter cannons and rainbows!Basically, aren't we all just hunting for joy through our jobs, our love lives, and maybe that overpriced yoga retreat? Because let's be honest, if those things led to misery, we'd be binge-watching Netflix instead. (Okay, some days we do both.)So, how do you actually find this magical life purpose?If you boil down every self-help book ever written (and I've read a LOT), two ideas bubble to the surface, like so much kombucha. They create two distinct, shall we say, *vibes* about Life.Vibe #1: Purpose is “Out There!”This is the story we're constantly sold, the narrative with all the bells and whistles. It's the idea that purpose and happiness are about *doing* and *getting*.What exactly are you supposed to be getting?Well, according to the marketing gurus (who are probably sipping martinis on a yacht somewhere), it's always - More! Better!More experiences, more influence, a passive income stream that makes your eyes water, a better house with a walk-in closet for your shoes, a better job that feeds your soul AND pays the bills, better sex (because, duh), and for the truly enlightened, a better, more Instagrammable spirituality.It's always *better* than what you've got right now, darling. But here's the cosmic joke: More and Better *never* actually deliver. As that wise old grump Ecclesiastes put it: "Meaningless! Meaningless! Everything is meaningless! But…life is still amazing.” (Even he couldn't help but throw in an "amazing" at the end!)We all kinda know this, right? We feel it in our bones after every online shopping spree. Still, those clever ads keep whispering promises. So, we jump back on the hamster wheel, convinced *this time* it'll be different. A new job! A soulmate who understands our obsession with miniature dachshunds! A truly transformative experience involving a llama!The catch? It's always a future promise. "Once I _______, then I'll find purpose/happiness/meaning."Once I quit my soul-crushing job, I'll finally be happy.Once I meet Mr./Ms. Right, then I'll know what love REALLY is.The future, my friend, is perpetually "tomorrow." That's the lie behind Vibe #1. The “hedonic treadmill” will leave you exhausted and feeling slightly used. Vibe #2: Your Purpose and Happiness are *Here, Now* Because Honey, *You ARE* the Purpose.The mind really throws a tantrum at this one based on how we've been programmed to have a “PURPOSE.”What if the truth is ridiculously simple: You *are* your purpose? You're here to know and be your glorious, messy, authentic Self as you cast your VISION and allow the listening to answer your CALLING (more on this on my next series of purpose). Seriously, pause for a moment and let that sink in.You're here to express your utterly unique, wonderfully weird, creative Self fully, freely, and fearlessly.Everything else such as your creativity, your relationships, your questionable fashion choices – are just sparkling byproducts of you being *you*.Knowing and being yourself? That's the answer to "What is my highest purpose and the source of my deepest freakin' joy?"The hitch? We've forgotten who we are. From childhood, we get handed a cookie-cutter mold for the "Good Life" who to be, what to want, what success looks like.So, we spend our lives trying to squish ourselves into that mold, developing a seriously messed-up case of mistaken identity. Then BAM! Quarter-life crises! Mid-life meltdowns! (It's all very dramatic, really.) So, how do you start?Embrace the Disillusionment, Darling.If you're feeling a little… blah about life, congratulations! You're right where you need to be. Disillusionment is inevitable. We no longer grasp to who we thought we were, and the one “purpose” we have in this life - and feeling that pressure!Even if you achieve all the things, the shine wears off. (That's just physics.)Own it. There's wisdom in that “blah” feeling. The pain of disillusionment can unlock a whole new, glittery world of freedom and possibilities.Why?Disillusionment means shedding the illusions. Seeing through the B.S. The cultural story that says purpose is “out there” is just a cleverly disguised sales pitch.You've checked the boxes, achieved the goals. But how long did it last? How long before you were chasing the next spiritual high?Spiritual goals are fabulous, but notice how we're always trying to *escape* those uncomfortable feelings.We launch projects, start cleanses, binge-watch cat videos. But eventually, we're back to the same damn questions.Wherever you go, there you are (and your existential baggage). So, you might as well embrace it.Disillusionment is an invitation. Like a pang of hunger, it's your True Self nudging you toward the truth.Look around. Mental illness is on the rise. Loneliness is an epidemic. People are quietly quitting their lives. Clearly, something's gotta give. The way we work, the way we live, the way we define "purpose"… it's all crumbling.That old story that purpose is “out there” keeps us stuck. That's the real question, isn't it? Who are you?Or, more accurately, *what* are you?Time to reframe this, Darling.What Is Your Vision and Soul Calling?A Vision is the art of seeing life's possibilities unfold—a profound and intuitive process that bridges the gap between your inner truth and the external world. It invites you to see not only the road ahead but also the unseen opportunities that lie along your path. Unlike conventional purpose driven vision, which often confines itself to specific, tangible goals, a calling embraces the unknown and empowers you to trust in the unfolding of your life's purpose. It is both a lens and a compass, helping you navigate toward your authentic self.The roots of the word “vision” are steeped in ancient wisdom. Derived from the Proto-Indo-European WEID, meaning “to see” or “to know,” the concept of vision transcends time and space. It reminds you that seeing is not merely a physical act but a deeper knowing—a connection to clarity and purpose that originates from within. THEREFORE. The vision Creates the PATH. Your Calling, is your Life's pursuit of multiple variations as a creator - offering insight and guidance that arises organically from your inner self, rather than being dictated by external expectations.Kassandra

Send us a textDr. Kilian Kelly, Ph.D. is Chief Executive Officer and Managing Director of Cynata Therapeutics ( https://cynata.com/ ), a stem cell and regenerative medicine company that is known for its proprietary Cymerus platform, for the scalable and consistent production of mesenchymal stem cell (MSC)-based therapies.Unlike traditional MSC therapies that rely on multiple donors, the Cymerus manufacturing process ensures that cells for therapeutic use can be produced in virtually limitless quantities from a single donor – making the opportunities endless and attractive from a manufacturing standpoint. The company has completed Phase I studies for Graft vs Host disease & Diabetic Foot Ulcers and have a number of Phase II, and even have a Phase III clinical trial, in progress.Dr. Kelly has over 20 years' experience in biopharmaceutical research and development, including almost 15 years focused on the development of mesenchymal stem cell (MSC) based therapies. He joined Cynata in March 2014, initially as Vice President, Product Development, then Chief Operating Officer from May 2019, and since July 2023 has been CEO & MD. At Cynata, he has overseen all stages of the development of the Cymerus induced pluripotent stem cell (iPSC)-derived MSC technology, including the first completed clinical trial of any iPSC-derived product worldwide.Dr. Kelly previously held positions at Biota Pharmaceuticals, Mesoblast Limited, Kendle International, Amgen and AstraZeneca. Dr. Kelly holds a Masters in Pharmacy degree from the Robert Gordon University, Aberdeen, a Ph.D. in Pharmaceutical Sciences from Strathclyde University, Glasgow, and he is a Graduate of the Australian Institute of Company Directors (AICD), Melbourne. He is a member of the International Society for Cell and Gene Therapy (ISCT), the International Society for Stem Cell Research (ISSCR), the Royal Pharmaceutical Society and the AICD.Dr. Kelly also serves on the ISCT Asia-Pacific Industry Committee, the ISSCR Best Practices Working Group for the Development of PSC-Derived Therapies and the Industry Interface Committee of the Center for Commercialization of Regenerative Medicine (CCRM) Australia.#KilianKelly #CynataTherapeutics #InducedPluripotentStemCells #MesenchymalStemCells #Immunomodulation #Immunoregulation #Mesenchymoangioblasts #GraftVersusHostDisease #GVHD #MSC #iPSC #IschaemicHeartDisease #Osteoarthritis #AcuteRespiratoryDistressSyndrome #ARDS #Inflammation #Secretome #Paracrine #RegenerativeMedicine #DiabeticWounds #KidneyTransplantation #ProgressPotentialAndPossibilities #IraPastor #Podcast #Podcaster #ViralPodcast #STEM #Innovation #Technology #Science #ResearchSupport the show

Kindly Subscribe to the channel to support the podcast by clicking the link: ⁠⁠⁠⁠⁠⁠⁠⁠https://creators.spotify.com/pod/show/blessing-masawi/subscribe⁠⁠⁠⁠STANDING ON THE PROMISES (THE POTENCY OF WORD-DERIVED FAITH) WITH APOSTLE JOSHUA SELMAN ||06|04|2025

Send us a text message and tell us your thoughts.Have you ever wondered about the beautiful complexity that arises when different cultures blend? The Caribbean term "Dougla" captures exactly that—specifically describing people of mixed African and Indian heritage in Trinidad and Tobago, Guyana, and Suriname. Today we unpack this fascinating identity that emerged from the region's colonial past of enslavement and indentured servitude. Derived from the Hindi word "Dogala" (meaning "double" or "mix"), the term once carried negative connotations but has been powerfully reclaimed as a symbol of pride. This blending of worlds symbolizes the Caribbean's remarkable capacity for cultural resilience and reinvention. It reminds us that some of humanity's most beautiful creations emerge at the intersection of different traditions. Subscribe to Strictly Facts for more explorations of Caribbean history and culture, and join our conversation about the diverse heritage that shapes our world today!Support the showConnect with Strictly Facts - Instagram | Facebook | Twitter | LinkedIn | YouTube | Website Looking to read more about the topics covered in this episode? Subscribe to the newsletter at www.strictlyfactspod.com to get the Strictly Facts Syllabus to your email!Want to Support Strictly Facts? Rate & Leave a Review on your favorite platform Share this episode with someone or online and tag us Send us a DM or voice note to have your thoughts featured on an upcoming episode Donate to help us continue empowering listeners with Caribbean history and education Produced by Breadfruit Media

In this podcast, Dr. Valentin Fuster discusses a groundbreaking study on mild aortic stenosis, which redefines its diagnostic threshold using deep learning and velocity-encoded MRI. The findings suggest that even mild cases, previously considered benign, are linked to increased cardiovascular risks, highlighting the potential for early intervention and the critical role of AI in advancing cardiovascular research.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Unsupervised Learning-Derived Complex Metabolic Signatures Refine Cardiometabolic Risk

Andrew Jackson is a man with a mission. After working in social housing for more than 10 years, he had a yearning to make outdoor spaces better for residents. Upon buying his own new build home, he realised how daunting it can be to suddenly have a blank canvas, full of promise, yet not have a clue what to do with it.  Years later, after finding his feet with that new garden, Andrew has put together a rather fantastic New Build Manifesto, which makes some strong suggestions for how housing developers can better prepare residents for their new outdoor space. He believes his manifesto is in harmony with the housing developer world, whilst also having firm environmental benefits. Hear all about it in this episode of the podcast. As ever, @ellenmarygardening and @mr_plantgeek gossip about anything that comes to mind but especially about Spring!   Sponsors of series 17 are Lava-Lite  - Naturally The Best Effortlessly nourish and protect your plants with a collection of totally non-toxic, environmentally friendly, sustainable, pH neutral, lightweight and 100% natural products. Derived from volcanic deposits, LAVA-LITE was formed by nature over 10,000 years ago. The collection is made up of eight different horticultural growing/potting media and pest control products, with each continually offering the same natural benefits: thermal protection, moisture retention and control, soil conditioning and providing a nutrient boost; as well as being completely child, pet and environmentally safe. LAVA-LITE is chemically inert, zero-harm and does not kill pests. It acts as a natural barrier and deterrent, providing an opportunity for them to simply move on. All the products can be used anywhere in the home and garden without worry and any predators eating prey that have come in to contact with LAVA-LITE will not be harmed, keeping eco-systems balanced, maintained and sustainable. The LAVA-LITE collection is available in handy 1 litre and 3 litre resealable pouches. They are easy to use, provide great results and don't require careful handling, making them perfect for the novice gardener and specialist grower. Learn more at www.lava-lite.co.uk

After it was approved in 2019, Spravato, a depression treatment derived from the club drug ketamine, was looking like a dud. But recently it has taken off, and it surpassed $1 billion in annual sales last year for its maker, Johnson and Johnson. Further Listening: -A Lawyer Says He Doesn't Need Help for Psychosis. His Family Disagrees.  -America's Maternal Mental Health Crisis  Further Reading: -J&J's Ketamine-Derived Drug Is Taking Off  -Big Pharma Walked Away From Mental Health. Why Some Are Coming Back.  Learn more about your ad choices. Visit megaphone.fm/adchoices

They're new, novel for many, and sales are booming. Hemp-derived THC drinks are changing store shelves and consumer purchase behaviors. This segment represents some of the highest potential for compound annual growth rate across all forms of cannabis and cannabis-adjacent products in coming years. Most importantly, those sales increasingly occur in common places people are already shopping: bottle shops, liquor stores, and other chain retail.The total hemp-derived THC market grew around +20% in 2024, with much driven by increased availability of beverages. And with no sign of waning interest from consumers across large swaths of the country, it's vital to understand what's next.Bryan Roth (Director of Insights, Sightlines)Bryan Roth leads consumer and market analysis for Sightlines. He develops frameworks and ideas that allow for decision-makers to thrive in beer and other alcohol categories. With over 10 years as a beverage-alcohol analyst, his work helps make ambiguous trends and emerging consumer behaviors more tangible, relevant, and actionable.Kate Bernot (Lead Analyst, Sightlines)Kate Bernot uses her reporting background to develop content for Sightlines subscribers, as well as leads panel discussions and industry roundtables about the future of beer and other alcohol categories. With more than 10 years of work across mass media, trade, and insights services, she's routinely cited as the beer and beverage alcohol industry's most prolific and impactful analyst.Stay up to date with CBP: craftbeerprofessionals.org

What if we could trade without trusting anyone?Crypto promised decentralization, but most trading still relies on centralized exchanges.In this episode of Web3 with Sam Kamani, I sit down with Alexis from Yellow.com to discuss: ✅ Why trustless trading is the missing piece in crypto✅ How Yellow is bringing Lightning Network principles to trading ✅ The billion-dollar opportunity in building a trustless settlement layer ✅ Lessons from Bitcoin, Ethereum & early crypto pioneers✅ Why traditional finance will soon adopt trustless tradingYellow.com is building the infrastructure to remove trust from trading—just like Bitcoin did for money.Key Timestamps[00:00:00] Introduction: Sam introduces Alexis from Yellow.com and the discussion on trustless trading, crypto innovation & finance disruption.[00:01:00] Who is Alexis?Co-founder of Yellow.com & GSR, two major crypto firmsA crypto OG since 2013, involved in Bitcoin, Ethereum, & RippleBuilt two companies with 500+ employees globally[00:03:00] What is Yellow.com?A trustless trading infrastructure that removes counterparty riskUses Ethereum state channels for instant PNL settlementsA missing piece in Satoshi's vision—removing trust from trading[00:05:00] Why is Trustless Trading So Important?Trust limits financial innovationBitcoin removed trust in money; Yellow removes trust in tradingMost crypto trading still relies on trusted intermediaries[00:07:00] How Yellow Uses State Channels for Instant Profit SettlementSimilar to Lightning Network but for tradingTrades settle instantly without requiring counterparty trustInstitutions & retail can trade against exchanges without risk[00:10:00] How Big is the Trading Industry?Payments industry: $8 Trillion per dayTrading industry: $650 Trillion per dayCrypto trading is tiny in comparison—trustless trading unlocks new markets[00:12:00] How Yellow Compares to Clearing Houses in Traditional FinanceClearSync smart contracts replace clearing housesAutomated, trustless arbitration using EthereumFaster, cheaper, and safer than legacy systems[00:14:00] Biggest Challenges in Building YellowEducating institutions & traders on trustless tradingAdoption curve similar to Bitcoin & Ethereum in the early daysConvincing major players to shift from centralized models[00:18:00] Lessons from Bitcoin & Ethereum's Early DaysVitalik Buterin & early Ethereum days in BarcelonaThe anti-system movement that fueled Bitcoin's riseWhy removing trust has always been the key innovation in crypto[00:21:00] The Future of Crypto Trading—Mergers, Acquisitions & ConsolidationMajor banks & exchanges will start consolidatingRobinhood acquiring Bitstamp, Crypto.com buying licensesTraditional finance is preparing for the crypto wave[00:25:00] Yellow's Growth & Future RoadmapLaunching a US-regulated public sale via RepublicExpanding partnerships with institutional players like HSBCBuilding a global community around trustless trading[00:27:00] Why the Name ‘Yellow'?Derived from the Dolch word list—one of the world's most recognized wordsInstant brand recognition across all languages & culturesA branding masterstroke for a global financial infrastructureConnecthttps://yellow.com/https://www.linkedin.com/company/yellow-com/https://x.com/Yellowhttps://www.linkedin.com/in/sirkia/https://x.com/AlexisYellowDisclaimerNothing mentioned in this podcast is investment advice and please do your own research. Finally, it would mean a lot if you can leave a review of this podcast on Apple Podcasts or Spotify and share this podcast with a friend.Be a guest on the podcast or contact us - https://www.web3pod.xyz/

In this podcast, Felix GV, Principal Staff Engineer at LinkedIn, discusses how to create and operate planet-scale data storage solutions for derived data. When it's time to build a new system, how do you decide on the pieces that must be fitted to ensure a resilient operating system? Read a transcript of this interview: https://bit.ly/3R7dsC5 Subscribe to the Software Architects' Newsletter for your monthly guide to the essential news and experience from industry peers on emerging patterns and technologies: https://www.infoq.com/software-architects-newsletter Upcoming Events: QCon London (April 7-10, 2025) Discover new ideas and insights from senior practitioners driving change and innovation in software development. https://qconlondon.com/ InfoQ Dev Summit Boston (June 9-10, 2025) Actionable insights on today's critical dev priorities. devsummit.infoq.com/conference/boston2025 InfoQ Dev Summit Munich (October 15-16, 2025) Essential insights on critical software development priorities. https://devsummit.infoq.com/conference/munich2025 QCon San Francisco 2025 (17-21, 2025) Get practical inspiration and best practices on emerging software trends directly from senior software developers at early adopter companies. https://qconsf.com/ InfoQ Dev Summit New York (Save the date - December 2025) https://devsummit.infoq.com/ The InfoQ Podcasts: Weekly inspiration to drive innovation and build great teams from senior software leaders. Listen to all our podcasts and read interview transcripts: - The InfoQ Podcast https://www.infoq.com/podcasts/ - Engineering Culture Podcast by InfoQ https://www.infoq.com/podcasts/#engineering_culture - Generally AI: https://www.infoq.com/generally-ai-podcast/ Follow InfoQ: - Mastodon: https://techhub.social/@infoq - Twitter: twitter.com/InfoQ - LinkedIn: www.linkedin.com/company/infoq - Facebook: bit.ly/2jmlyG8 - Instagram: @infoqdotcom - Youtube: www.youtube.com/infoq Write for InfoQ: Learn and share the changes and innovations in professional software development. - Join a community of experts. - Increase your visibility. - Grow your career. https://www.infoq.com/write-for-infoq

By now you have probably heard of social prescribing and perhaps even social and therapeutic horticulture and as gardeners we know that gardening makes us feel good, but what about everyone else? What about people with no access to green space, people with mental and physical health issues and what about those tasked with giving advice, support and suggestions to help - such as a medical professional.    In this episode guest Dr. Richard Claxton -a champion of promoting positive health and wellness through plants and gardens - tells us what and how gardening truly helps people stay well.   Sponsors of series 17 are Lava-Lite  - Naturally The Best Effortlessly nourish and protect your plants with a collection of totally non-toxic, environmentally friendly, sustainable, pH neutral, lightweight and 100% natural products. Derived from volcanic deposits, LAVA-LITE was formed by nature over 10,000 years ago. The collection is made up of eight different horticultural growing/potting media and pest control products, with each continually offering the same natural benefits: thermal protection, moisture retention and control, soil conditioning and providing a nutrient boost; as well as being completely child, pet and environmentally safe. LAVA-LITE is chemically inert, zero-harm and does not kill pests. It acts as a natural barrier and deterrent, providing an opportunity for them to simply move on. All the products can be used anywhere in the home and garden without worry and any predators eating prey that have come in to contact with LAVA-LITE will not be harmed, keeping eco-systems balanced, maintained and sustainable. The LAVA-LITE collection is available in handy 1 litre and 3 litre resealable pouches. They are easy to use, provide great results and don't require careful handling, making them perfect for the novice gardener and specialist grower. Learn more at www.lava-lite.co.uk

Mark Bjornstad, Drekker Brewing, is in studio on Afternoons Live with Tyler Axness to tell us why he is advocating for a study to research the production of hemp derived THC drinks in North Dakota.See omnystudio.com/listener for privacy information.

On the podcast in this episode is the editor of one of the most popular gardening magazines in the UK, Amateur Gardening. The magazine was founded in 1884, but sadly stopped production back in late 2023… but thankfully resurrected just a few months later, with a whole new look, making a whole nation of gardeners of all ages very happy.   Editor and author Kim Stoddart is with @ellenmarygardening and @mr_plantgeek to talk all about editorial deadlines and of course, gardening!   Afterwards Michael and Ellen chat random stuff from travels to plants and everything in between.    Sponsors of series 17 are Lava-Lite  - Naturally The Best Effortlessly nourish and protect your plants with a collection of totally non-toxic, environmentally friendly, sustainable, pH neutral, lightweight and 100% natural products. Derived from volcanic deposits, LAVA-LITE was formed by nature over 10,000 years ago. The collection is made up of eight different horticultural growing/potting media and pest control products, with each continually offering the same natural benefits: thermal protection, moisture retention and control, soil conditioning and providing a nutrient boost; as well as being completely child, pet and environmentally safe. LAVA-LITE is chemically inert, zero-harm and does not kill pests. It acts as a natural barrier and deterrent, providing an opportunity for them to simply move on. All the products can be used anywhere in the home and garden without worry and any predators eating prey that have come in to contact with LAVA-LITE will not be harmed, keeping eco-systems balanced, maintained and sustainable. The LAVA-LITE collection is available in handy 1 litre and 3 litre resealable pouches. They are easy to use, provide great results and don't require careful handling, making them perfect for the novice gardener and specialist grower. Learn more at www.lava-lite.co.uk

In this solo episode of Modern Chiropractic Mastery with Dr. Kevin Christie, chiropractors are guided through common capacity blocks hindering their practice growth. Derived from Dr. Christie's work with Strategic Coach, these capacity blocks include lacking support team members, clinical duplication, limited space and equipment, mindset issues, time constraints, delegation challenges, cash flow problems, and marketing deficits. Dr. Christie emphasizes the importance of viewing support team members as investments and discusses how tools and coaching can help overcome these obstacles. He highlights the concept of 'even better' growth and provides detailed insights into addressing underlying problems that prevent chiropractors from breaking through the ceiling of complexity in their practice.

Dr. Simrit Parmar, Founder of Cellenkos, is developing T regulatory cell therapies from cord blood to treat aplastic anemia, myelofibrosis, and acute lymphoblastic leukemia. Their three-prong strategy focuses on resolving inflammation and alleviating the burden of transfusions. Treg cells from cord blood are naturally tolerant and do not risk rejection, meaning they can be administered to patients without the need for matching. The cells can be consistently manufactured in a scalable way and distributed globally. Simrit explains, "Tregs, the T regulatory cells, are actually regulators of our immune system. So if you think about it every day as a human being, we face many challenges. We face many insults and injuries to our body, both externally and internally, but our body has a way to maintain that balance. The T regulatory cells are the cells that are the mastermind of making sure that any response by our body, for example, to get rid of an antigen or to get rid of an irritant does not overstay the welcome because our body utilizes the mechanism of inflammation to get rid of these injuries or these insults." "So umbilical cord blood is, or the umbilical cord is, the connection between the baby, the fetus, and the mother. And if you think about it, the baby is 50% mismatched to the mother, and nature allows it. Nature allows a permissive environment where the baby can grow and eventually give birth, and the whole species is advanced. What happens is that nature has allowed the tolerance, and one of the mechanisms by which this tolerance, the maternal-fetal tolerance, is induced by the very T regulatory cells that populate the conduit between the mother and the baby, is the cord blood. So what we did is harness the power that nature has bestowed upon these cells to just do one job and one job only, which is to resolve inflammation. This is the fundamental reason we went after cord blood as a starting material because as a physician and drug developer, we wanted to make sure that the product, the cells we're giving into the patient, are doing its job."  #Biotechnology #DrugDevelopment #LifeSciences #AplasticAnemia #Myelofibrosis #GVHD #ALS #Tregs #CellTherapies #TargetedTherapies #AutoimmuneDiseases   cellenkosinc.com   Download the transcript here  

Dr. Simrit Parmar, Founder of Cellenkos, is developing T regulatory cell therapies from cord blood to treat aplastic anemia, myelofibrosis, and acute lymphoblastic leukemia. Their three-prong strategy focuses on resolving inflammation and alleviating the burden of transfusions. Treg cells from cord blood are naturally tolerant and do not risk rejection, meaning they can be administered to patients without the need for matching. The cells can be consistently manufactured in a scalable way and distributed globally. Simrit explains, "Tregs, the T regulatory cells, are actually regulators of our immune system. So if you think about it every day as a human being, we face many challenges. We face many insults and injuries to our body, both externally and internally, but our body has a way to maintain that balance. The T regulatory cells are the cells that are the mastermind of making sure that any response by our body, for example, to get rid of an antigen or to get rid of an irritant does not overstay the welcome because our body utilizes the mechanism of inflammation to get rid of these injuries or these insults."  "So umbilical cord blood is, or the umbilical cord is, the connection between the baby, the fetus, and the mother. And if you think about it, the baby is 50% mismatched to the mother, and nature allows it. Nature allows a permissive environment where the baby can grow and eventually give birth, and the whole species is advanced. What happens is that nature has allowed the tolerance, and one of the mechanisms by which this tolerance, the maternal-fetal tolerance, is induced by the very T regulatory cells that populate the conduit between the mother and the baby, is the cord blood. So what we did is harness the power that nature has bestowed upon these cells to just do one job and one job only, which is to resolve inflammation. This is the fundamental reason we went after cord blood as a starting material because as a physician and drug developer, we wanted to make sure that the product, the cells we're giving into the patient, are doing its job." #Biotechnology #DrugDevelopment #LifeSciences #AplasticAnemia #Myelofibrosis #GVHD #ALS #Tregs #CellTherapies #TargetedTherapies #AutoimmuneDiseases cellenkosinc.com   Listen to the podcast here  

Nevis Brands CEO John Kueber joined Steve Darling from Proactive to announce a major milestone for the company—the national launch of Happy Apple, a hemp-derived THC beverage designed to offer a smooth, relaxing experience without the drawbacks of alcohol. Already a popular choice in Washington State's regulated dispensary market, Happy Apple will now be available in dozens of states across the U.S., marking a significant expansion for Nevis Brands. The company has successfully adapted its well-loved formula—a natural, sparkling apple beverage—by replacing the traditional THC component with a hemp-derived alternative. This shift ensures compliance with federal regulations while maintaining the same refreshing taste and enjoyable effects that made Happy Apple a standout product in the cannabis beverage market. Kueber highlighted that under the 2018 Farm Bill, hemp-based products containing less than 0.3% Delta-9 THC are federally legal in the United States. This regulatory clarity has opened the door for thousands of mainstream retailers, including major liquor store chains, to stock hemp-derived THC beverages. The demand for these products is surging, with market research firm Brightfield Group reporting that the hemp-derived cannabis beverage sector generated $382 million in sales in 2024. This market is projected to nearly double, reaching approximately $750 million in the U.S. by 2029. Unlike its traditional licensing model, where Nevis Brands partners with third-party producers to bring its products to market, the company is taking a more direct approach with the Happy Apple hemp-derived line. Nevis is managing sales and distribution through a combination of strategic partnerships with distributors and direct-to-consumer online sales. This shift allows the company to retain a larger share of revenues while strengthening its brand presence in the rapidly growing hemp-based beverage industry. With a proven product and an expanding national footprint, Nevis Brands is well-positioned to capitalize on the rising demand for hemp-derived THC beverages, providing consumers with an innovative, alcohol-free alternative for relaxation and social enjoyment. #proactiveinvestors #nevisbrandsinc #cse #nevi #otcqb #nevif #majorbrand #cannabis #THC #Hemp #CannabisIndustry #HappyApple #THCBeverage #CannabisBusiness #CBD #HempDrink #CannabisInvesting

Have you done all you can to prevent a würm infestation? I doubt it. This week on the Vintage RPG Podcast, we chat with Brian Colin about Sqwürmish, a delightfully gross, over-the-top miniature skirmish game for his Vast Grim RPG setting. Derived from Forbidden Psalm, in Sqwürmish you build a crew, pop 'em on the table and do your damnedest to survive, preferably without getting infested with würms (ew). Like Forbidden Psalm, you can play with any old miniatures you have laying around, but this Kickstarter includes some very sweet miniatures, for use with Sqwürmish or Vast Grim! Get 'em, and some neon paints and maybe some of that drippy gloss varnish and get that war gang good and yicky! * * * Back Sqwürmish on Kickstarter now! And check out the rest of the Vast Grim universe! * * * Instagram? Old news. Join the Vintage RPG Newsletter! That's where all the cool kids are now! Stu's book, Monsters, Aliens, and Holes in the Ground is for sale now! Buy it! Patreon? Discord? Cool RPG things to buy? All the Vintage RPG links you need are right here in one place! Like, Rate, Subscribe and Review the Vintage RPG Podcast! Edited by the one and only R. Alex Murray. Send questions, comments or corrections to info@vintagerpg.com. Available on iTunes, Google Podcasts, iHeartRadio, Spotify, YouTube and your favorite podcast clients. The Vintage RPG illustration is by Shafer Brown. Follow him on Twitter. Tune in next week for the next episode. Until then, may the dice always roll in your favor!

BUFFALO, NY - February 10, 2025 – A new #casereport was #published in Volume 16 of Oncotarget on February 5, 2025, titled “A case report of donor cell–derived hematologic neoplasms 9 years after allogeneic hematopoietic cell transplantation." In this case report, Aleksandra Mroczkowska-Bękarciak and Tomasz Wróbel from Wroclaw Medical University describe a rare and serious complication after a stem cell transplant. The case involves a patient who, nine years after receiving a stem cell transplant for acute myeloid leukemia (AML), developed a new, aggressive blood cancer originating from donor cells. Despite receiving treatment, the disease progressed to myelodysplastic syndrome/acute myeloid leukemia (MDS/AML), ultimately leading to the patient's death. Stem cell transplants are a life-saving treatment for many blood cancers, including AML. While relapse of the original cancer is the most common concern, this case highlights another rare but serious complication: the development of donor cell-derived hematologic neoplasms (DCHN). The report details the case of a 23-year-old woman who remained in remission for nearly 10 years following a successful hematopoietic stem cell transplant from an unrelated donor. However, she later developed a new form of leukemia, driven by genetic mutations in the ASXL1, SETBP1, and EZH2 genes—biomarkers linked to highly aggressive blood cancers. Over the next two years, the disease progressed despite intensive treatment, ultimately proving fatal. This case highlights the need for continued monitoring of transplant recipients, even years after the procedure. Although DCHN is extremely rare, its occurrence raises critical questions about the process by which donor cells transform into leukemia. Some stem cell donors may unknowingly carry genetic mutations that are harmless in their own bodies but could trigger cancer in recipients. Additionally, factors such as immunosuppressive therapy, bone marrow stress, and transplantation procedures may contribute to these rare but deadly outcomes. “Early diagnosis and intervention are crucial to improving patient prognosis.” Ongoing research is focused on improving donor screening methods to help predict and prevent these complications. In the future, routine genetic testing for stem cell donors could become a standard part of the transplant process, helping clinicians identify potential risks before transplantation. More studies are needed to fully understand why donor-derived cancers develop and how they can be prevented. With continued progress in precision medicine and genetic diagnostics, researchers aim to make stem cell transplants safer and more effective for all patients. DOI - https://doi.org/10.18632/oncotarget.28686 Correspondence to - Aleksandra Mroczkowska-Bękarciak - omroczkowska@interia.pl Video short - https://www.youtube.com/watch?v=G2zd0UqWzeE About Oncotarget Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science. Oncotarget is indexed and archived by PubMed/Medline, PubMed Central, Scopus, EMBASE, META (Chan Zuckerberg Initiative) (2018-2022), and Dimensions (Digital Science). To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Life-The Spiritual Essence: An Engineer's Insights into the Integrated Nature of Divinity by Deepak Parashar Linkedin.com Amazon.com The transformative journey of the author, an engineer, began with “chance” blessings from the 14th Dalai Lama of Tibet. Over 12 years of research ensued across 38 countries on how the substratum of energy interconnects our world under the umbrella of divinity—traversing the realms of science and spirituality, philosophy, 15 religions, nature, cultures, and locales. With timely support from subject matter experts, including a NASA astronaut, a WWII Nuremberg Trials prosecutor, a Tuskegee airman, clergy, holistic educators, as well as leaders from industry, defense, and the arts; the author combined over 25,000 pages of his research and travels to draw insights into life's spiritual essence. The outcomes encompass a strategic, holistic system for daily improvement; an integrated energy model explaining our cooperative existence; and the iterative science behind five major religions. Derived analyses include modern leadership philosophies rooted in ancient scriptures applied across diverse professions, and a spiritual travelogue that transcends boundaries by embracing profound topics such as the depths of human suffering, the heights of natural wonder, and the diverse realms of art and culture. "Life—The Spiritual Essence" serves as an encyclopedic resource for the global professional, providing diverse avenues for exploration and growth through cheerful dynamism to achieve excellence while serving the larger community. The message emphasizes hope at its core, drawing inspiration from the paths of leaders throughout history, powered on by our innate curiosity and grit to surpass personal boundaries to achieve lasting peace. With over 65 illustrations and pictures,"Life—The Spiritual Essence" includes: Table A: The Six Trigger Points, tested over seven years, serve as an illuminating holistic system for the mind organized into six action-oriented quadrants. Presented on a single page for daily review, they provide critical behavior analysis, driving subliminal improvements while studying admirable traits in the common man and leaders alike. By exploring their various permutations and combinations, one can analyze most daily experiences within this framework. And achieving over 50 percent alignment with these triggers invariably leads to a fulfilling day! Table B-1: Provides a comprehensive technical analysis of Hinduism's perspective on the creation of the universe, exploring its views from macrocosmic to microcosmic levels elucidating the genesis of life, and delineating the pathway towards transcendence. Table B-2: Examines the vision and iterative science behind Hinduism, Christianity, Islam, Buddhism and Judaism. While some may perceive it as comparative, its focus lies in offering a structural analysis across 16 cardinal pillars that energize these age-old philosophies. This effort evolved over several years working with clergy, religious scholars, and holistic educators. Table C: Pursuant to the analyses in Tables A, B-1, and B-2, the author identifies specific boundary conditions and presents a comprehensive model that seamlessly integrates divinity, drawing upon the elements outlined earlier. Grounded in energy as the unifying substratum, it bridges the qualitative and quantitative aspects to elucidate the inclusive nature of reality. Spiritual Travelogue: The author's global quest delves into the essence of divinity through profound encounters, bridging theory and practice. These encompass seeking wisdom from figures like the Dalai Lama, poignant visits to WWII Concentration Camps, primal nature excursions into tornado alley (USA) and the sub-Arctic to witness the enchanting aurora borealis, to examining divinity within the fine arts, notably music and cinema. These rich experiences invite readers to contemplate the intricate tapestry of cultu...

Todays podcast is with Beth Williams, multidisciplinary artist and fashion designer who creates living textiles with incredible designs based around plants and nature. Beth centres around an inaccessible world as well as the relationship between human and environmental sustainability.    Afterwards, @ellenmarygardening and @mr_plantgeek gossip separately with news of what they have been up to recently.    Sponsors of series 17 are Lava-Lite  - Naturally The Best Effortlessly nourish and protect your plants with a collection of totally non-toxic, environmentally friendly, sustainable, pH neutral, lightweight and 100% natural products. Derived from volcanic deposits, LAVA-LITE was formed by nature over 10,000 years ago. The collection is made up of eight different horticultural growing/potting media and pest control products, with each continually offering the same natural benefits: thermal protection, moisture retention and control, soil conditioning and providing a nutrient boost; as well as being completely child, pet and environmentally safe. LAVA-LITE is chemically inert, zero-harm and does not kill pests. It acts as a natural barrier and deterrent, providing an opportunity for them to simply move on. All the products can be used anywhere in the home and garden without worry and any predators eating prey that have come in to contact with LAVA-LITE will not be harmed, keeping eco-systems balanced, maintained and sustainable. The LAVA-LITE collection is available in handy 1 litre and 3 litre resealable pouches. They are easy to use, provide great results and don't require careful handling, making them perfect for the novice gardener and specialist grower. Learn more at www.lava-lite.co.uk

Exosomes are being touted as “the next retinol” amongst the biotech world, the who's who of facialists and now – celebrity makeup artists. Brought to you in part by our friends at Plated Skin Science, we're diving into the buzzy skincare brand that transformed Emma Stone's makeup artist Rachel Goodwin's rosacea-prone skin (Pssst! Megan Fox is also a fan.)Listen in as Alisa Lask, CEO of Rion Aesthetics (the parent company of Plated Skincare) explains exosomes vs. growth factors, how exosomes actually work to regenerate your skin cells and the surprising source of their human-derived platelet ingredient.Tune in to hear:Why the platelet-derived exosomes technology in Plated's Intense Serum was the *only* skincare product to be recognized on Time magazine's "Best Inventions of 2024" list. Are all exosomes created equal? How to know if what's on the label is legitHow to incorporate exosomes into your current skincare routineWho should incorporate exosomes into their routines, and who should not The future of exosome technology - A solution for thinning hairlines, for real? For any products or links mentioned in this episode, check out our website: https://breakingbeautypodcast.com/episode-recaps/ Get social with us and let us know what you think of the episode! Subscribe to our YouTube channel and find us on Instagram, Tiktok, Twitter. Join our private Facebook group. Or give us a call and leave us a voicemail at 1-844-227-0302. Sign up for our newsletter here Related episodes like this: Peptides! Growth Factors! Exosomes! The Buzziest Skincare Ingredients To Know Now. Plus - Overcoming Trauma and Building Skin Confidence With Allies of Skin Founder Nicolas TravisThe Ultimate Sensitive Skin Girls' Guide: Transitioning to a Winter Skincare Routine, “Barrier Bulking” and The Ingredients That *Really* Make a Difference with First Aid Beauty's Jenna HaleyCortisol Face, Fascia Care and How-to Brow Lift At Home With The Facialist's Facialist, Maria Cristina BrunoPROMO CODES: When you support our sponsors, you support the creation of Breaking Beauty Podcast! PlatedPlated Skin Science is the first brand delivering platelet-derived exosomes to treat visible signs of aging. Learn more at platedskinscience.com or find Plated at your favorite aesthetic medical provider. NutrafolNutrafol is the #1 dermatologist-recommended hair growth supplement brand, trusted by over 1 million people. For a limited time, Nutrafol is offering our listeners $10 off your first month's subscription and free shipping when you go to Nutrafol.com and enter the promo code BREAKING. HersCurious about semaglutide medications for weight loss? Start your initial free online visit today at forhers.com/BREAKINGBEAUTY *Disclaimer: Unless otherwise stated, all products reviewed are gratis media samples submitted for editorial consideration.* Hosts: Carlene Higgins and Jill Dunn Theme song, used with permission: Cherry Bomb by Saya
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New plant breeding is big business, but often people ask why we even need new plants. In this episode @ellenmarygardening and @mr_plantgeek with Garry Grueber who is well known in the world of plant development, with over 40 years of experience. It's an insightful chat into the world of new plants. Afterwards, Michael and Ellen chat about plant catwalks, conveyor belts and the cold.    Sponsors of series 17 are Lava-Lite  - Naturally The Best Effortlessly nourish and protect your plants with a collection of totally non-toxic, environmentally friendly, sustainable, pH neutral, lightweight and 100% natural products. Derived from volcanic deposits, LAVA-LITE was formed by nature over 10,000 years ago. The collection is made up of eight different horticultural growing/potting media and pest control products, with each continually offering the same natural benefits: thermal protection, moisture retention and control, soil conditioning and providing a nutrient boost; as well as being completely child, pet and environmentally safe. LAVA-LITE is chemically inert, zero-harm and does not kill pests. It acts as a natural barrier and deterrent, providing an opportunity for them to simply move on. All the products can be used anywhere in the home and garden without worry and any predators eating prey that have come in to contact with LAVA-LITE will not be harmed, keeping eco-systems balanced, maintained and sustainable. The LAVA-LITE collection is available in handy 1 litre and 3 litre resealable pouches. They are easy to use, provide great results and don't require careful handling, making them perfect for the novice gardener and specialist grower. Learn more at www.lava-lite.co.uk

Dr. Michelle Peace is an internationally recognized forensic toxicologist and a Full Professor in the Department of Forensic Science at Virginia Commonwealth University. The National Institute of Justice has funded her team to study the proliferation of semi-synthetic THC analogs in the unregulated market and define their relevant biomarkers. Her work impacts public health and public safety policies and initiatives. At CannMed 25 Michelle will present “Why Some People “Green Out”? The Analysis of Unregulated “Hemp-derived” Cannabis Products”. Her team used a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to analyze unregulated hemp products. All the products they analyzed were mislabeled in some way, either misrepresenting the cannabinoids contained therein or their concentrations.  During our conversation we discuss What has caused the rise of semi-synthetic cannabinoids in the market?  How Michelle got involved testing unregulated hemp and cannabis products  Some of the adverse events that have occured from consuming semi-synthetic cannabinoids  How the LS-MS/MS method allows Michelle's team to see compounds other labs can't   How consumers can protect themselves from mislabeled products Whether federal legalization of cannabis would eliminate the semi-synthetic market  Thanks to This Episode's Sponsor: PRICH Biotech PRICH Biotech, Corp. is a vertically integrated company dedicated to the cultivation, manufacture and dispensing of medicinal Cannabis in Puerto Rico.  With over 500,000 square feet of state-of-the-art facilities, Prich uses the highest standards of agricultural and manufacturing practices to guarantee the highest standard of medicinal cannabis. Their mission is to offer a natural and unique experience through medicinal cannabis that raises the patient's well-being and quality of life. Learn more at prichbiotech.com.  Additional Resources Register for CannMed 25 Meet the CannMed 25 Speakers Review the Podcast CannMed Archive

Stock market update for January 21, 2025. Check out our Instagram account @TheRundownDaily

In October 2024, ITRC released the 6PPD & 6PPD-quinone Guidance Document to provide environmental professionals and communities with information about the current science and regulatory framework of 6PPD and 6PPD-quinone (6PPD-q). 6PPD-q is a contaminant of emerging concern and is a transformation product of the tire anti-degradant (6PPD), an antiozonant used in tires. Join us for this ITRC training course to get a basic overview of the science and policy measures surrounding the Tire Anti-Degradants 6PPD and 6PPD-q. Attendees will gain insight into the current state of knowledge on topics such as: background and use of 6PPD in tires, toxicity in aquatic species and humans; occurrence, fate, and transport; measuring, mapping, and sampling; mitigation measures; and policy, regulations, and laws. Currently, 6PPD is used in all tires and can contaminate stormwater and surface water anywhere tires are used. 6PPD-q was identified as a chemical fatal to coho salmon in 2020. Since that time, it has been documented as acutely toxic to multiple trout species found throughout the United States. 6PPD and 6PPD-q have been found in waterways, aquatic organisms, soils, air, and humans. This training will introduce you to the ITRC 6PPD & 6PPD-quinone Guidance Document which provides more technical detail than can be covered in this training course To view this archive online or download the slides associated with this seminar, please visit http://www.clu-in.org/conf/itrc/6PPD-Q_011425/

Plants don't always follow the expected rules or genders, and it's not a big deal for them, yet why is it for us? Connor Butler gives us some some truths about everything LGBTQ+ in the botanical world…and it's fascinating!  Afterwards @ellenmarygardening and @mr_plantgeek have a new years gossip while driving to Heathrow about travel and of course plants, amongst other random things.    Sponsors of series 17 are Lava-Lite  - Naturally The Best Effortlessly nourish and protect your plants with a collection of totally non-toxic, environmentally friendly, sustainable, pH neutral, lightweight and 100% natural products. Derived from volcanic deposits, LAVA-LITE was formed by nature over 10,000 years ago. The collection is made up of eight different horticultural growing/potting media and pest control products, with each continually offering the same natural benefits: thermal protection, moisture retention and control, soil conditioning and providing a nutrient boost; as well as being completely child, pet and environmentally safe. LAVA-LITE is chemically inert, zero-harm and does not kill pests. It acts as a natural barrier and deterrent, providing an opportunity for them to simply move on. All the products can be used anywhere in the home and garden without worry and any predators eating prey that have come in to contact with LAVA-LITE will not be harmed, keeping eco-systems balanced, maintained and sustainable. The LAVA-LITE collection is available in handy 1 litre and 3 litre resealable pouches. They are easy to use, provide great results and don't require careful handling, making them perfect for the novice gardener and specialist grower. Learn more at www.lava-lite.co.uk

Primary immunodeficiency disorders include more than 400 conditions, and a growing number of people are being recognized as having them as a result of improved diagnostic tools and greater awareness among physicians. Most treatments for these conditions are plasma-derived therapies sourced from donors. We spoke to Joerg Schuettrumpf, chief scientific innovation officer at Grifols, about the changing landscape for these conditions, the challenges of ensuring a reliable supply of plasma-derived therapies, and how treatment options may evolve.

Sunday, 22 December 2024   And if you greet your brethren only, what do you do more than others? Do not even the tax collectors do so? Matthew 5:47   “And if you embrace only your brothers, what extra do you do? And do not the taxmen, the ‘himself' they do?” (CG).   In the previous verse, Jesus noted the pointless nature of expecting rewards when you love those who love you, noting that even tax collectors do that. Now, He continues that thought, saying, “And if you embrace only your brothers.”   He uses the word aspazomai. Strong's Lexicon says, “Derived from a (as a particle of union) and a presumed form of spao (to draw); meaning to enfold in the arms, i.e., to greet or embrace.” Although most translations simply say greet, salute, hail, or something similar, the word indicates a hearty welcome where the arms enfold around someone.   Today, we might grab someone, pull him closer, put one arm around him, and then give him a pat on the back. It is a welcome that demonstrates felicity. When greeting a brother like this, Jesus questions them about it, asking, “what extra do you do?”   The obvious answer is, “nothing.” It is what everyone who greets a brother or a friend does. This is so obvious that He next says, “And do not the taxmen, the ‘himself' they do?”   Some manuscripts use the word ethnikoi, those from non-Jewish ethnicity, rather than telonai, taxmen, as was seen in the previous verse. Either way, the point is made. Jesus uses an example of someone who is considered contemptible by the Jews, demonstrating that this is what everyone does, regardless of culture, social status, etc.   He will next finish the chapter with words that sum up His thoughts on the matter that He has been addressing.   Life application: There are various ways that manuscripts will wind up with differences in them. In the case of Matthew 5:47, what seems likely is that it was a case of dittography. This is where a letter or word is repeated by accident. In the Greek NT Text, the final sentence is almost identical except for one word, translated as tax collectors by the NKJV: ἐὰν γὰρ ἀγαπήσητε τοὺς ἀγαπῶντας ὑμᾶς, τίνα μισθὸν ἔχετε; οὐχὶ καὶ οἱ τελῶναι τὸ αὐτὸ ποιοῦσιν; καὶ ἐὰν ἀσπάσησθε τοὺς ἀδελφοὺς ὑμῶν μόνον, τί περισσὸν ποιεῖτε; οὐχὶ καὶ οἱ ἐθνικοὶ τὸ αὐτὸ ποιοῦσιν;   For if you love those who love you, what reward have you? Do not even the tax collectors do the same? And if you greet your brethren only, what do you do more than others?Do not even the tax collectors [ethnicities] do so?   When translating verse 47, the Greek copyist looked up, his eyes probably glanced at verse 46 by accident, thus writing taxmen a second time instead of pagans or ethnicities. This is obviously speculation, but somehow an error crept into one of the two texts.   To understand why there are various differences in the biblical texts, take time to read up on copyist errors. Along with dittography, some of the errors you will discover are haplography (omitting a repeated letter or word), metathesis (reversing letters or words), homeoteleuton (skipping a section due to similar line endings), and homeoarchy (skipping a section due to similar beginnings of lines).   These and other copyist mistakes frequently crept into texts. Does this mean that the word of God is tainted? Not at all. It is there, but we must spend time and careful consideration to determine why the error occurred and which is the original. Though disputed by various scholars, the original exists.   The Greek New Testament has thousands and thousands of manuscripts. Add in lectionaries, commentaries, and other ancient sources, and the originals can be determined. God has allowed fallen man to handle His word. Because of this, errors in transmission can be expected. But diligence and perseverance will lead to a fuller and closer understanding of what was originally given under inspiration of the Spirit.   Lord God, thank You for those who have carefully recorded Your word over the ages, passing down what You originally gave us so that we can understand what You have done in the giving of Jesus. Help us to diligently search out Your word and faithfully transmit it to those around us so that they, too, can know. Amen.  

By 2025, millennials are projected to become the largest segment of the global workforce, comprising over 75% of employees, according to Pew Research Center. This generational shift presents both opportunities and challenges for organizations seeking to inspire effective leadership in a rapidly evolving and divided world. In this episode, Fred sits down with Susan Inouye, a leadership expert and advocate for Sawubona Leadership. Derived from the Zulu greeting meaning "I see you," Sawubona Leadership emphasizes authentic connection, empathy, and empowerment—principles that resonate deeply with millennials seeking purpose-driven careers and inclusive workplaces. Key questions explored during this engaging discussion include: How can Sawubona Leadership transform relationships between leaders and their teams? Why are millennials uniquely positioned to bring people together in today's divided world? What practical steps can executives and senior managers take to embrace this leadership philosophy? Susan shares her mission to spread the principles of Sawubona to leaders at all levels, providing actionable insights to help organizations cultivate leaders who can drive collaboration, innovation, and unity. Listeners can learn more about Susan and her work at www.susaninouye.com/theleadershipcode.

My links: My Ko-fi: https://ko-fi.com/rhetoricrevolution Send me a voice message!: https://podcasters.spotify.com/pod/show/liam-connerly TikTok: ⁠https://www.tiktok.com/@mrconnerly?is_from_webapp=1&sender_device=pc⁠ Email: ⁠rhetoricrevolution@gmail.com⁠ Instagram: https://www.instagram.com/connerlyliam/ Podcast | Latin in Layman's - A Rhetoric Revolution https://open.spotify.com/show/0EjiYFx1K4lwfykjf5jApM?si=b871da6367d74d92

Speaking of SurgOnc has a new home! New episodes can now be found under the Society of Surgical Oncology's podcast, SurgOnc Today, available on all major podcast platforms. Subscribe today to receive updates on new episode releases.  In this new episode of Speaking of SurgOnc, Dr. Rick Greene discusses with Dr. Michael Bouvet and Dr. Kristin Cox the applicability of M5A-IR800 to target human gastric cancer, as reported in their article, "Targeting Patient-Derived Orthotopic Gastric Cancers with a Fluorescent Humanized Anti-CEA Antibody."

Speaking of SurgOnc has a new home! New episodes can now be found under the Society of Surgical Oncology's podcast, SurgOnc Today, available on all major podcast platforms. Subscribe today to receive updates on new episode releases.  In this new episode of Speaking of SurgOnc, Dr. Rick Greene discusses with Dr. Michael Bouvet and Dr. Kristin Cox the applicability of M5A-IR800 to target human gastric cancer, as reported in their article, "Targeting Patient-Derived Orthotopic Gastric Cancers with a Fluorescent Humanized Anti-CEA Antibody."

Send us a textCHRISTThe Name | Part 2Dr. Jessica FernandezDecember 8, 2024#god #realspringcreekchurch #christ #thename What's in a name? In Scripture, names are more than just labels—they reveal identity, purpose, and destiny. The name Christ is no exception. Derived from the Greek Christos, meaning "Anointed One," it is the Greek translation of the Hebrew word Mashiach or "Messiah". This name declares Jesus as the chosen and empowered Savior, Prophet, Priest, and King. In this message, we'll explore the profound meaning of the name Christ and how it reveals Jesus' mission and identity. Together, we'll discover how understanding Him as the Anointed One can transform the way we see Him, love Him, and follow Him. This Christmas season let's move beyond familiarity and embrace the depth of who Jesus truly is as the Christ—the fulfillment of God's promises and the hope of the world.__ DISCUSSION QUESTIONS 1. What does the name "Christ" reveal about Jesus' identity and mission?2. How do titles like Prophet, Priest, and King deepen your understanding of Jesus?3. What cultural or personal misconceptions about Jesus might you need to address?4. How can Simeon and Anna's faithfulness inspire your walk with God today?5. In what ways does recognizing Jesus as Christ shape your daily life and decisions?

The U.S. Food and Drug Administration has approved cannabis-derived medications for several indications. In this episode, family practitioner Randy Easterling, MD, highlights the current regulatory status of FDA-approved cannabis-derived medications and their approved uses.     ⭐⭐⭐⭐⭐

BUFFALO, NY - November 25, 2024 – A new #editorial was #published in Oncotarget's Volume 15 on November 12, 2024, entitled, “Visualizing radiological data bias through persistence images.” This editorial highlights a powerful tool called "persistence images," which could improve how medical imaging and artificial intelligence (AI) systems are developed and used. Authors Yashbir Singh, Colleen Farrelly, Quincy A. Hathaway, and Gunnar Carlsson from the Department of Radiology, Mayo Clinic (Rochester, MN), provide a detailed explanation of how persistence images uncover hidden biases and advance fairness in healthcare AI. AI is becoming a major part of healthcare, helping clinicians analyze X-rays, magnetic resonance imaging, and computed tomography scans. However, if the data used to train AI systems is biased, it could lead to unfair or inaccurate results. Derived from topological data analysis (TDA), persistence images transform complex medical scans into simple, stable visuals. These images make it easier to spot patterns or irregularities that could indicate bias. For example, they can reveal whether certain groups—such as patients of a specific age, gender, or ethnicity—are underrepresented in the data used to train AI systems. “The use of persistence images in radiological analysis opens up new possibilities for identifying and addressing biases in both data interpretation and AI model training...” This could help ensure that AI systems work equitably for all patient groups, resulting in more reliable diagnoses and better outcomes. In addition to detecting bias, persistence images also help filter out noise, or irrelevant details, from medical scans. This makes it easier for both AI systems and radiologists to focus on meaningful features in the images, improving overall accuracy. These insights help AI systems perform better and make more accurate, trustworthy decisions. Despite their potential, persistence images face challenges. Generating persistence images for large datasets demands substantial computing power, while integration into clinical workflows requires user-friendly tools and specialized training for healthcare professionals. As healthcare becomes more data-driven, tools like persistence images could transform how medical imaging is used. “By helping us visualize and address hidden biases, they can contribute to improved patient outcomes and more personalized healthcare delivery.” In conclusion, this editorial envisions a future where advanced mathematical tools like persistence images play a vital role in eliminating bias and improving patient outcomes. Integrating these tools into clinical workflows could enhance radiological analysis, setting new standards for accuracy and equity in healthcare worldwide. DOI - https://doi.org/10.18632/oncotarget.28670 Correspondence to - Yashbir Singh - singh.yashbir@mayo.edu Video short - https://www.youtube.com/watch?v=sQELv8oi3ew About Oncotarget Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science. Oncotarget is indexed and archived by PubMed/Medline, PubMed Central, Scopus, EMBASE, META (Chan Zuckerberg Initiative) (2018-2022), and Dimensions (Digital Science). To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Derived from the playing of the Nation Brothers https://www.slippery-hill.com/content/magnolia-one-step-2

Derived from the playing of the Nation Brothers https://www.slippery-hill.com/content/magnolia-one-step-2

BUFFALO, NY - November 20, 2024 – A new #editorial was #published in Oncotarget's Volume 15 on November 12, 2024, entitled, “Persistence barcodes: A novel approach to reducing bias in radiological analysis.” This editorial, authored by Yashbir Singh, Colleen Farrelly, Quincy A. Hathaway and Gunnar Carlsson from the Department of Radiology, Mayo Clinic (Rochester, MN), introduces persistence barcodes as a groundbreaking tool in medical imaging, particularly radiology. Derived from topological data analysis (TDA), this method transforms complex medical images into clear, interpretable patterns. By highlighting features such as tissue densities, blood vessels, and tumors, persistence barcodes reduce diagnostic bias and uncover subtle details that traditional artificial intelligence (AI) systems might miss. This innovative approach holds great promise for enhancing diagnostic accuracy and improving patient care. Unlike some AI tools, like Graph Neural Networks, which risk oversmoothing and blurring critical features, persistence barcodes preserve key structural details. This method visualizes how features in medical images emerge, persist, and fade across different scales, providing clearer insights into the data. By detecting subtle changes in tissue density that could indicate early disease and filtering out irrelevant artifacts or noise from imaging errors, persistence barcodes enhance diagnostic accuracy and reliability. Persistence barcodes enhance fairness and consistency by standardizing analyses across different machines and radiologists, ensuring reliable diagnoses regardless of the imaging system. Their robustness against equipment-related variations makes them a valuable tool for improving diagnostic accuracy in diverse clinical settings. While promising, the integration of persistence barcodes into routine medical practice faces challenges, such as the computational demands of processing high-resolution images and the need for user-friendly visualization tools. “As we continue to refine and validate this approach, persistence barcodes could play a crucial role in developing more accurate, consistent, and unbiased diagnostic tools. This, in turn, has the potential to improve patient outcomes and advance the field of radiology as a whole.” In conclusion, with continued development and refinement, persistence barcodes have the potential to revolutionize medical imaging by facilitating earlier and more accurate disease detection, minimizing diagnostic errors, and significantly improving patient outcomes. DOI - https://doi.org/10.18632/oncotarget.28667 Correspondence to - Yashbir Singh - singh.yashbir@mayo.edu Video short - https://www.youtube.com/watch?v=eVOqpV2vFsg Subscribe for free publication alerts from Oncotarget: https://www.oncotarget.com/subscribe/ About Oncotarget Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science. Oncotarget is indexed and archived by PubMed/Medline, PubMed Central, Scopus, EMBASE, META (Chan Zuckerberg Initiative) (2018-2022), and Dimensions (Digital Science). To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

This month on Repast Michael and Diana talk with Amanda Howell, managing attorney at the Animal Legal Defense Fund. They discuss a recent petition by the ALDF to the FDA urging the FDA require the disclosure of animal-derived ingredients on package labels, along with other work the ALDF is doing right now.  Amanda Howell is a managing attorney at ALDF. Michael T. Roberts is the Executive Director of the Resnick Center for Food Law & Policy at UCLA Law. Diana Winters is the Deputy Director of the Resnick Center for Food Law & Policy at UCLA Law. You can find ALDF's petition to the FDA here. A list of cases ALDF is involved in can be found here. The Food Allergen Labeling and Consumer Protection Act of 2004, discussed in the podcast, cab be found here.

Jerry Grover, accomplished Geologist and Linguist has cracked the code of the Jaredite King's names and believes they derived from Sumerian and is here to bring the receipts! #Christian #mormon #archaeology #bible #bookofmormon #jaredites #manguage #reformedegyptian #josephsmith #kingjames --- Support this podcast: https://podcasters.spotify.com/pod/show/wardradio/support

Welcome to Episode #172 of The Coaching Podcast! This week, we're thrilled to be joined by Toby Jenkins, a dynamic executive coach, speaker, Olympian, and entrepreneur with a mission: to change the world's relationship with suffering. Toby's journey has taken him from the Olympic pool to the boardroom, where he's helped shape the mental resilience of everyone from military elites to tech founders. In our conversation, we explore the transformative power of psychological flexibility, discuss what it means to shift from 'harder, tougher, stronger' to a mindset of alignment, and dive into the nuances of performance behavior and acceptance commitment therapy. Get ready for an episode packed with deep insights and powerful tools to elevate your coaching approach. 1.45: What position in AFL would you like to play? 2.28: How did you discover water polo and what's your first early memory of a coach? 4.58: What was your experience of mental toughness as it relates to being an Olympian? Inspired by the awesome foursome and specifically Mike McKay (spelling) who had written on the bottom of the boat: Who – If not me, who? Now – If not now, when? Goal – Gold medal 8.21: Stoic Philosophy (Choice of Response) - The only control we have is the choices that we make. “If we can't control our reaction, how do we choose our response.” 9.05: Psychological Flexibility “As an Olympian – I thought I needed to be harder, tougher, stronger.” How can we help people rather than run through brick walls, instead, how do we help them become trampolines? This is the core shift in perspective of the performance mindset. “Buddha said that life is suffering and I tend to agree!” So how do we open up to that, acknowledge that, and still experience the joy? 11.35: What would you say to the coach who has had success with the ‘harder, tougher, stronger' approach? It's one tool in the coaching toolkit. It's not the absence of one, it's the presence of both. 13.26: Defining Psychological Flexibility as your ability to shift your attention. Derived from ACT which stands for: Acceptance Commitment Therapy Open up, be present, and do what matters because performance behavior is contextual. 15.32: Performance Behavior is defined as doing the thing that is less comfortable. ACT talks about moving towards behavior (short-term pain) and not positive and negative behavior. 18.36: Insights on balance (trade-offs) versus alignment (compounding)? 21.07: Key lesson - The most important work is never done (they are a set of practices). 24.01: Time Management - It is a non-renewable resource. 28.19: Sacrifice versus choice. 31.37: What makes a great coach? 1) Questions - "What if this was the last time?" 33.11: Disruptive coaching idea that will change the way we coach in 2030? AI may provide a coach for people in their pocket to accelerate the development of humans. 35.22: Toby's purpose: To change the world's relationship with suffering. 41.08: Crucible moment To learn more about becoming a workplace coach or advancing your coaching skills, visit: www.coachem.cc or email: info@emmadoyle.com.au About Toby Jenkins Toby is a husband, father, Olympian, executive coach, award-winning entrepreneur, and author. His purpose is to change the world's relationship with suffering. He's worked with a diverse group, from Olympians to business leaders, from military elites to tech founders. (Find out more about his coaching.) Toby has spoken to thousands of people in life and broadcast audiences around the world at organizations such as Google, Ernst & Young, Rio Tinto, and the Australian Institute of Sport. (Find out more about his speaking.) He's married to Lucy and father to Beatrix, Heidi, and Zoe. His favorite thing is writing about himself in the third person. Connect with Toby Website: https://www.tobyajenkins.com/The Monday 3 Newsletter: https://www.tobyajenkins.com/newsletter/ Insta: @tobyjenkins LinkedIn: https://www.linkedin.com/in/tobyjenkins/

Join us in The Locher Room for a special conversation with Emmy Award-winning producer, writer, and director, Jody Small.We'll be discussing her powerful one-hour documentary, The Storm & The Boats, which captures the raw, emotional, and diverse experiences of New Jersey residents during the COVID-19 pandemic. Derived from her Pandemic Stories Project, Jody filmed over 25 hours of oral histories in 2021 to preserve these stories for future generations. The documentary highlights the voices of healthcare workers, elected officials, students, parents, and many more, offering a personal narrative to the pandemic and its impact on mental health.Don't miss this the chance to listen to this insightful discussion with Jody Small, as we delve into the importance of preserving these vital stories for the permanent record. 

I'm Josh Cooperman and this is Convo By Design with a conversation about going home. You've heard the old adage, you can't go home again. Derived from the Thomas Wolfe novel published in 1940, posthumously. It's true, you can't go home again because so much changes in your absence. I went home recently to Manhattan Beach. It's true things change, but not everything and sometimes, change is good. Designer Resources Pacific Sales Kitchen and Home. Where excellence meets expertise. Monogram - It's the details that define Monogram ThermaSol - Redefining the modern shower experience. Without steam, it's just a bathroom. Design Hardware - A stunning and vast collection of jewelry for the home!  - Where service meets excellence TimberTech - Real wood beauty without the upkeep I love Manhattan Beach. One of the things I missed most after we moved to Oklahoma was walking down the greenbelt with kids and  getting dinner in downtown MB followed by a trip to the Creamery for an ice cream sandwich the likes of which you just can't find anywhere else. While there, I stopped into Brewco to speak with Michael Zislis, restaurateur, developer, hotelier and MB devotee. So much so, that through his restaurant and hotel development, has almost singlehandedly reshaped the city for the better over the past 30 years. We talked about the redevelopment of Brewco, an eatery on Manhattan Beach Boulevard and an iconic spot for those who've lived there or those who've come to visit. you're going to hear that and then, you are going to hear from Noelle Isbell, Manhattan Beach designer who took on the Brewco project in amazing fashion, called her shot and delivered a spot that is representative of Manhattan Beach's past, present and future. Turns out, you can go home again. Even if it's not exactly the same. If you love design, you are going to love this story. If you are a designer, this is how you go and get that project you have always wanted. And you are going to hear all about it, right after this. Thank you, Noelle and Michael, thank you for creating something that makes me feel at home!. Thank you to my partner sponsors, ThermaSol, Pacific Sales, TimberTech, Monogram and Design Hardware. These partners are amazing companies all who have made a concerted effort to support the design community through education, incentives, events, media and exposure, not to mention a collection of extraordinary products and service to match. Check the show notes for links to each of them so you can see first hand how they can make your design business thrive and your projects exceed expectations. Thank you for listening, downloading, subscribing and sharing the show with your friends and colleagues. Thank you for your emails, show and guest suggestions. Please keep them coming, convobydesign at Outlook dot com and on Instagram @ConvoXdesign, with an “x”.  Until the next episode, be well and take today first. - CXD

Topic: Archons and their Manipulative ControlIn this episode, we are diving deep into the conspiracy of the Archons, a force that manipulates humanity on every level, from emotions to political power structures. These are the ultimate antagonists of human freedom. Derived from Gnostic teachings, Archons are described as formless, energetic entities that hijack human consciousness, twisting it with fear, anxiety, and ignorance. Their control extends to the political elite, media, and corporations, essentially the "powers that be"—who operate as their human puppets.GET THE BOOK OF SACRET SECRETShttps://www.whythebigsecret.com/merchSubscribe to Youtubehttps://www.youtube.com/@whythebigsecretAntagonist: The Archons and Their Human PuppetsThe Archons are rulers in a cosmic hierarchy designed to keep humanity enslaved within a false reality, sometimes described as the Demiurge's prison. They can't create, only manipulate what already exists, twisting reality into an inverted version of the true cosmos. These entities use political leaders, corporations, and media empires as their foot soldiers, who consciously or subconsciously spread fear, misinformation, and division to maintain control .Protagonist: The Symbolizer (Roderick Martin )Standing against this vast, hidden system is Roderick Martin, the Symbolizer, a seeker exposing these hidden layers of manipulation and deception. The goal? To awaken the masses and break free from the false realities imposed on them by this elite-controlled system of lies. Your mission is to reveal the true nature of the world and tear down the veil that blinds people to the deeper, spiritual truth.Key Facts Exposing the Antagonist's Control:Emotional Manipulation: Archons feed on fear and anxiety. They use these negative emotions to keep humans trapped in a lower vibrational state. This feeds their power​.Perception Control: They manipulate human perceptions, ensuring we view the world through a distorted lens. This keeps the masses ignorant of their true potential .Political and Corporate Power: The Archons have infiltrated world governments and corporations, creating a one-percent elite who perpetuate wars, economic slavery, and environmental destruction to benefit from the chaos​.Layers of Deception to Uncover:The Illusion of Reality: Human society is structured like a prison, one that ensures people remain ignorant of their true spiritual nature. Archons manipulate through religion, mainstream science, and media​​.False Spirituality: Archons also distort religious and spiritual teachings, making humans worship them under various guises—Gods, Demons, Djinn, and Angels, when in fact, these are all just forms of the Archon deception​ .Who Benefits?The Archons thrive on the negative energy generated by human conflict, fear, and suffering. The Elite, their human counterparts, maintain their wealth, status, and power by keeping the world in a constant state of division, ensuring that no one questions the system​.What's at Stake?The stakes are high: the very freedom of human consciousness. If left unchecked, the Archons will continue to push humanity deeper into fear, division, and ignorance, ensuring their endless control over reality. Humanity's spiritual liberation and connection to the higher realms of consciousness are at risk​.

WYNK was founded in 2020 by Casey Parzych, Angus Rittenburg, and Shawn Sheehan, three friends (a beverage manufacturer, mechanical engineer, and energy trader) looking for a new opportunity in the cannabis beverage market. Their challenge: find a way to dose the seltzer with THC legally, as current laws for dispensary distribution require dosing in the states where the drinks will be sold. Today, WYNK is a hemp-derived  1:1 THC:CBD zero-calorie seltzer. WYNK's blend of THC and CBD offers a light and bubbly buzz that is enjoyable any night of the week. WYNK is made with all-natural flavors and comes in Black Cherry Fizz, Lime Twist, Juicy Mango, and newly released Tangerine. WYNK is available online for purchase in 37 states, and sold in retail stores in 12 states at www.drinkwynk.com. Angus joins Justin to discuss this innovative, and fast-growing, beverage brand.

In today's episode, we dive into the molecular mechanisms underlying neuroinflammation, with a particular focus on how gut-derived endotoxins, such as lipopolysaccharides (LPS), perturb the blood-brain barrier (BBB) and propagate neuroinflammatory cascades. In more detail, we'll discuss how intestinal dysbiosis and increased intestinal permeability can allow endotoxins such as LPS to enter systemic circulation and cross the blood-brain barrier (BBB), where they activate microglia via the TLR4 signaling pathway. We will explore symptoms including brain fog, memory impairment, mood disturbances, decreased concentration, and cognitive fatigue; as well as tools to support the gut-microbiota-brain axis. Topics: 1. Introduction to Neuroinflammation - Definition and general overview - Key brain cells: neurons, glial cells, and endothelial cells - Chronic neuroinflammation and microglial cells 2. Cellular Mechanisms of Neuroinflammation - Role of microglia in detecting damage or infection - Microglial activation through PRRs/TLRs - Release of pro-inflammatory cytokines and reactive oxygen species (ROS) - Impact on neurons and synaptic plasticity: memory and learning 3. Astrocytes in Neuroinflammation - Astrocytes' contribution to the inflammatory response 4. Chronic Neuroinflammation and Brain Health - Prolonged activation: oxidative stress, excitotoxicity, impaired synaptic function - Impairment of synaptic plasticity and cognitive decline - Mitochondrial dysfunction and cell death cascades - Compromised blood-brain barrier integrity 5. Contributing Factors to Neuroinflammation - Environmental toxins and pollutants, viral or bacterial infections, chronic sleep deprivation, and more 6. Intestinal Dysbiosis and Neuroinflammation - Role of Gram-negative bacteria and LPS (lipopolysaccharides) - Increased intestinal permeability and passage of LPS - LPS transport: transcellular and paracellular pathways - Impact on the blood-brain barrier (BBB) 7. LPS Activation of Microglia - LPS binding to TLR4 on immune cells - Microglial activation and cytokine release - Cognitive impairments and neurodegenerative processes 8. Intestinal Hyperpermeability - Bioindividual approaches: prebiotics, probiotics, polyphenols, bacteriophages - Support for intestinal mucus secretions and sources of mucilage - Butyrate - Glutamine 9. Beneficial Gut Microbiome-Derived Metabolites and Brain Health - Types of metabolites: SCFAs, tryptophan metabolites, polyphenol metabolites - Role of butyrate in crossing the BBB and modulating brain function - Influence on gene expression and synaptic plasticity - Contribution to gut barrier integrity and protection against endotoxins 10. Conclusion - Recap of neuroinflammation's impact on cognitive function + symptoms Thank you to our episode sponsor: 1. Check out ⁠⁠⁠⁠⁠Daily Nouri⁠⁠⁠⁠⁠ and use code ⁠⁠⁠⁠⁠CHLOE20⁠⁠⁠⁠⁠ for 20% off your order. Thanks for tuning in! Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow Chloe on TikTok @chloe_c_porter Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more! --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support

Welcome to the SYNC Your Life podcast episode #280! On this podcast, we will be diving into all things women's hormones to help you learn how to live in alignment with your female physiology. Too many women are living with their check engine lights flashing. You know you feel “off” but no matter what you do, you can't seem to have the energy, or lose the weight, or feel your best. This podcast exists to shed light on the important topic of healthy hormones and cycle syncing, to help you gain maximum energy in your life.  In today's episode, I'm diving into the launch of my. new favorite supplement: Triple Boost! This is a true industry disruptor in hormone health that every woman needs, and I couldn't be more excited to share. Derived from Canadian pea protein and Icelandic blue spirulina, it delivers 20g of full profile plant-based protein, BCAA's, and 230% of your daily value of methylated Vitamin B12. You can find the product here. I reference last week's podcast with Dr. David Lipman on MTHFR and methylation, which is important in understanding the power behind the methylcobalamin in Triple Boost. You can listen to that here. To learn more about 3rd party tested endocrine disruption free products to help you make simple swaps in your life, click here. To learn more about the SYNC fitness program, click here. You will need access to the core program before moving into the monthly membership.  To learn more about virtual consults with our resident hormone health doctor, click here. If you feel like something is “off” with your hormones, check out the FREE hormone imbalance quiz at sync.jennyswisher.com.  To learn more about the SYNC Digital Course, check out jennyswisher.com.  If you're interested in becoming a SYNC affiliate and Certified Coach mentored by me, you can learn more here. Let's be friends outside of the podcast! Send me a message or schedule a call so I can get to know you better. You can reach out at https://jennyswisher.com/contact-2/. Enjoy the show! Episode Webpage: jennyswisher.com/podcast 

As the largest organ of our body, our skin doesn't just reflect our inner health—it absorbs everything we expose it to, both the good and the bad. I had a fascinating conversation with Emily Rose, better known as Mama Wilder on social media, where we dug deep into the world of skincare and dangers of toxic chemicals.  Our skin is like a sponge, soaking up whatever we apply to it. We all know the risks of harmful chemicals like PFAS and toxins, which can easily enter our systems through the skin.  Parabens, for instance, are often used as preservatives but can mimic hormones and even contribute to early puberty in children. And those seemingly harmless fragrances? They're usually a mix of chemicals that can disrupt your endocrine system. Emily opened up about her struggles with skin issues, from cystic acne to trying every product under the sun, both natural and pharmaceutical. The biggest improvements came when she started focusing on reducing stress, nourishing her body with minerals, and steering clear of endocrine disruptors. Red light therapy involves low-level wavelengths of red light that can treat various skin issues, from reducing redness to soothing irritation. While it might be a bit of an investment, the results can be significant, with many users reporting a noticeable improvement in skin tone and texture. Beyond tech solutions like red light therapy, natural antioxidants like hydroxytyrosol are making waves in skincare. Derived from olives, hydroxytyrosol is a potent antioxidant with anti-inflammatory, anti-aging, and even anti-cancer properties. Skincare is about consistency. Regular exfoliation, lymphatic drainage, and moisturizing are essential for maintaining healthy, glowing skin. Climate, diet, and stress all play roles in how your skin responds to different products. The key is to find what works for you and stick with it. If you're feeling overwhelmed by all the options, start with one new product. Focus on what your skin really needs—whether it's hydration, acne treatment, or redness reduction. By simplifying your routine and cutting out unnecessary chemicals, your skin has a better chance to heal and thrive. Emily "Mama Wilder" is a single mom of two in Western Colorado, a birth educator, health coach and advocate for women's autonomy in the healthcare industry. Find Emily:  instagram.com/mama_wilder