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Play Nightlife's famous Mighty Challenge, our 25 question quiz.  

In this episode of “At Your Convenience,” Melissa Vonder Haar, managing director of TradeWorks for iSee Store Innovations and chair of CSP's C-Store Cannabis Board, talks to Diana Eberlein at the inaugural CSP Cannabis Forum. Eberlein is the chair of the Coalition for Adult Beverage Alternatives and chief communications officer for emulsion supplier Vertosa. The two discussed the urgent threat facing hemp-derived THC products due to a Nov. 12 federal deadline that could effectively ban most products on the market. They also emphasized the need for convenience retailers to educate consumers and legislators about the category's legitimacy and the industry's desire for proper regulation.The Cannabis Forum took place March 23-25 in Lombard, Illinois. For more information, visit informaconnect.com/c-store-cannabis-forum/.

In this week's episode of the Podscarf, we welcome legendary music producer Rick Rubin—who accidentally ruins our viewer retention stats before getting violently dragged off set—alongside Radio 1 DJ Melvin Odoom and Southwark Borough Fire Commander Daniel Capon for an hour of pure, unadulterated legacy media chat and safety protocols. If you've ever wanted to hear a group commander explain why you should never, under any circumstances, throw a bucket of water on a kitchen oil fire, or witness an adult man explain a legendary schoolyard Desmond's impression that culminates in a smelly finger, listen up. - 00:04 – Rick Rubin's Creative Process 01:37 – Analyzing the Podscarf Stats: The Sudden Rick Rubin Retraction Dip 02:27 – The Irish vs. Ghanaian Apostrophe Scandal with Melvin Odoom 02:49 – Radio 1 Live Lounge Lore: Chilling out with an Enigmatic Harry Styles 03:54 – Cantaloupe Melon Sugar: Harry Admits He Is Way Too Old for Current Music 04:44 – Licky the Mascot Debuts an Elaborate Swiss Army Taser Dance 05:58 – Selling Nine-Volt Batteries and Homemade Shock Equipment for £20 06:31 – Misidentifying Greg Wallace and Stalking the Aisles of Home Bargains 07:27 – Buying Eight-Foot Teddy Bears and Massive Boxes of Chewing Gum 08:03 – CDJs vs. Vinyl: Embracing the Technical Demise of Creative Revenue 09:29 – Sarah the AI Bot Offers a Fork Bump and Wants to Kiss Your FM 10:10 – Biographies of North London: From Cricklewood to Seven Sisters 11:06 – Minoring in Apple Trees: Learning How to Plan Content at Bedfordshire 11:56 – A-Level Acting Failures, Clearing, and Stanning Trevor Nelson 12:29 – Harry's Trendy Habits as a Six Music Dad Who Secretly Listens to Gold 13:15 – Student Radio Origin Stories and Trading Drama Classes for BBC Toast 13:53 – Fired From Capital Radio: The Demise of the 2004 Playlist 14:37 – Looking Out at the Aberdeen Museum of Steak while Evanescence Plays 15:24 – Welcome to Funch: The 18-to-24 Female Focus Group Disaster 16:49 – Chatting Rubbish vs. Real Work: Melvin's Mum the Dementia Care Worker 17:36 – Demanding Jollof Rice and Chicken 18:00 – Sarah Breaks Down the 2009 Kiss Breakfast Sony Radio Silver Award 18:48 – Dick and Dom Bungalow Memories and Bleeding Love on a Miniature Guitar 19:57 – The Nose-Flute Solo Experiment 22:02 – Steve Wright's The Slammer and Getting Your Foot on the Rung via Free Toast 23:03 – Strictly Christmas Revenge and Scored Minuses on House of Games 24:16 – Celebrity Take Me Out Lift Entrances and a Fake Date at a Holborn Bowling Alley 25:27 – E4's My Hotter Half: Using Mood Lighting to Make Over Ugly Couples 26:12 – Naked Attraction Musings: Releasing Inhibitions and Boosting Ratings 27:42 – SUV Entrances on Traitors and Marvin Humes' Jungle Eating Warnings 29:32 – GK Barry Pulls Out of the Show to Go to the Brit Awards 30:18 – Gifting a Best Single Brit Award to an Incredibly Beautiful James Blunt 31:12 – Rick Rubin's Hamburg Cutlery Shop Memory: Paul McCartney's Missing Spoons 32:00 – Making a Clack-Clack Sound on Cherry Bakewell with German Forks 33:07 – Firefighting: Welcoming Daniel Capon (The D-Man) from Southwark 33:38 – Surviving the 24-Hour Operational Officer Shift Patterns 34:06 – Dispelling Misconceptions: 20,000 Fires vs. 56,000 Special Services 34:38 – The Ultimate London Fire Brigade Statistic: Exactly Five Cats Rescued from Trees 35:27 – Dripping Radiators and Calling 999 Because the Gardener Smashed a Window 36:58 – Modern Prevention Safety: Utilizing Free Station Community Rooms 38:39 – The Nature of Big Red Toolboxes and Fixing Things by Default 39:22 – Cooking Left Unattended: The Demise of the 1970s Damp Tea Towel Protocol 40:48 – Sixty-Second Station Mobilization and the Speed Efficiency of the Fire Pole 41:08 – Harry's 1976 Maidstone Scout Firefighter Badge Strike Trauma 42:31 – Lithium-Ion Charge Safe Campaigns: The E-Bike Battery Threat 43:22 – Containing Black Smoke Inhalation by Keeping Property Doors Firmly Closed 44:39 – The Unsung Heroes of the LFB Control Room Network 47:05 – Heartwarming and Heartbreaking Families: Working a 30-Year Career 48:34 – Online Home Fire Safety Checkers for Vulnerable London Residents 50:14 – GAME TIME: "What is the Velcro Singing?!" 51:36 – Mistaking Leona Lewis for Little Mix Black Magic and Only Fools and Horses 53:22 – Gary's Joke Corner (Melvin's Historic Desmond's Impression) 55:19 – Old African Sayings: Itchy Bums, Smelly Fingers, and Schoolyard Training 55:34 – Butterfly In Blue Jeans "Melvin Odoom" by Wikipedia contributors, used under CC BY-SA 4.0. Derived from the Wikipedia article on Melvin Odoom. / This work is licensed under CC BY-SA 4.0. Learn more about your ad choices. Visit podcastchoices.com/adchoices

What if the milk you are drinking could help fight cancer? In this episode of Tomorrow's Cure, we explore cholangiocarcinoma and a surprising new approach to targeting it using milk‑derived nanoparticles and precision aptamer‑based delivery. Host Lindsey Seavert is joined by surgical oncologist Dr. Rory Smoot and long‑term survivor and advocate Melinda Bachini to unpack why this cancer is so challenging, what symptoms and treatment paths patients typically face, and how emerging gene‑delivery platforms and AI‑driven discovery are opening new possibilities when standard therapies fall short. Through Melinda's 16‑year survivorship story and Dr. Smoot's lab work that literally starts with skim milk from the Mayo Clinic cafeteria, listeners hear how “chemical antibodies” called aptamers can act as molecular keys to deliver therapy directly to cholangiocarcinoma cells, and how computational tools are accelerating the search for new targets. Together, they discuss the emotional and practical realities of living at the edge of what medicine can do today, the expanding landscape of clinical trials, and why innovation in this rare cancer may ripple out to colon, lung and other hard‑to‑treat tumors. How to listen and stay connected: Subscribe to Tomorrow's Cure on your favorite podcast app and follow the show so you never miss an episode. Get the latest health information from Mayo Clinic's experts—subscribe to Mayo Clinic's newsletter for free today: https://mayocl.in/3EcNPNc Connect with Mayo Clinic: Like Mayo Clinic on Facebook: https://www.facebook.com/mayoclinic/ Follow Mayo Clinic on Instagram: https://www.instagram.com/mayoclinic/ Follow Mayo Clinic on X (formerly Twitter): https://x.com/MayoClinic Follow Mayo Clinic on Threads: https://www.threads.net/@mayoclinic

Read the article here: https://journals.sagepub.com/doi/full/10.1177/30494826261450851

Guest: In this special episode recorded live in Montréal, Canada at ISSCR 2026, Dr. Michael May, President and CEO of the Centre for Commercialization of Regenerative Medicine (CCRM), and Dr. Janet Rothberg, Senior Director of Process and Analytical Development at CCRM, explore how stem cell discoveries can be translated into commercially viable therapies through scalable manufacturing, company creation, investment, automation, and artificial intelligence. They emphasize the importance of considering manufacturing, quality control, market selection, reimbursement, and the evolving standard of care much earlier in the development process. They also share their vision for a future in which robust bioprocessing, better use of data, and improved regulatory and reimbursement models make iPSC-derived therapies more affordable and widely accessible.  Photo Reference: Courtesy of Drs. Michael May and Janet Rothberg Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

I personally subscribe to The Economist. TOE listeners get 35% off the annual subscription. No other podcast has this! https://economist.com/TOE Ginestra Bianconi thinks gravity can be derived from entropy — and that gravity itself is fundamentally anti-reductionistic, since it's about geometry rather than isolated particle interactions. In this episode, the network-topologist-turned-gravity-theorist explains her "Gravity from Entropy" action, which treats matter and geometry symmetrically through a geometric quantum relative entropy (not the horizon entropy of Verlinde or Jacobson). She details why it reduces to Einstein's equations at low energy while predicting a dynamical, always-positive dark energy term (the "G field"), how it may avoid black hole singularities and reproduce the area law without invoking holography, and why she believes understanding the brain may be harder than understanding quantum gravity. We close with her advice for young researchers. I hope you enjoy. TIMESTAMPS: - 00:00 - Information Content of Geometry - 07:38 - Geometric Quantum Relative Entropy - 15:58 - Geometrizing the Matter Field - 23:45 - Emergent Dark Energy - 30:12 - Statistical Mechanics vs Thermodynamics - 37:59 - Structure and Dynamics Interplay - 45:20 - Holography and Area Law - 51:23 - Interdisciplinary Research Vision LINKS MENTIONED: Ginestra's Webpage: https://webspace.maths.qmul.ac.uk/g.bianconi/ Ginestra's Papers: https://scholar.google.com/citations?user=ycQXwWgAAAAJ Gravity from Entropy [Paper]: https://arxiv.org/abs/2408.14391 Geons, Black Holes, and Quantum Foam [Book]: https://amazon.com/dp/0393319911?tag=toe08-20 The Thermodynamics of the Gravity from Entropy Theory [Paper]: https://arxiv.org/abs/2510.22545 Notes on Some Entanglement Properties of Quantum Field Theory [Paper]: https://arxiv.org/abs/1803.04993 Inflation from Entropy [Paper]: https://arxiv.org/abs/2509.23987 Thermodynamics of Spacetime: The Einstein Equation of State [Paper]: https://arxiv.org/abs/gr-qc/9504004 More Is Different [Paper]: https://www.science.org/doi/10.1126/science.177.4047.393 Information, Physics, Quantum [Paper]: https://philpapers.org/archive/WHEIPQ.pdf Network Geometry with Flavor [Paper]: https://arxiv.org/abs/1511.04539 Black Holes and Entropy [Paper]: https://physicsgg.me/wp-content/uploads/2014/03/black-holes-and-entropy_bekenstein.pdf Ginestra's Lecture on Higher-Order Networks: https://youtu.be/o4TWDTgqQKY Elan Barenholtz [TOE]: https://youtu.be/A36OumnSrWY Frederic Schuller [TOE]: https://youtu.be/Bnh-UNrxYZg Erik Verlinde [TOE]: https://youtu.be/ilVImMHcr_g Ted Jacobson [TOE]: https://youtu.be/3mhctWlXyV8 Karl Friston [TOE]: https://youtu.be/2v7LBABwZKA Subir Sarkar [TOE]: https://youtu.be/epkuoytFJWA Stephen Wolfram [TOE]: https://youtu.be/FkYer0xP37E Roman Yampolskiy [TOE]: https://youtu.be/TgFmA-Qwsek Eva Miranda [TOE]: https://youtu.be/6XyMepn-AZo Cumrun Vafa [TOE]: https://youtu.be/kUHOoMX4Bqw Neil Turok [TOE]: https://youtu.be/zNZCa1pVE20 David Kaiser [TOE]: https://youtu.be/_yebLXsIdwo Ivette Fuentes [TOE]: https://youtu.be/YWbjI-QsH2E Philip Mannheim [TOE]: https://youtu.be/rNXNHYvS7zU FOLLOW: - Spotify: https://open.spotify.com/show/4gL14b92xAErofYQA7bU4e - Substack: https://curtjaimungal.substack.com/subscribe - Twitter: https://twitter.com/TOEwithCurt - Discord Invite: https://discord.com/invite/kBcnfNVwqs - Crypto: https://nowpayments.io/donation/TOE - PayPal: https://www.paypal.com/donate?hosted_button_id=XUBHNMFXUX5S4 Guests do not pay to appear. #science Learn more about your ad choices. Visit megaphone.fm/adchoices

In this week's episode of the Podscarf we welcome English stand-up comedian Angela Barnes and Tudor historian Adam Pennington to the studio for an hour of pure, unadulterated high-street nostalgia and medieval gore. Angela reveals how she used to operate as a suitcase-wielding, bootleg DVD library out of her dad's Great Yarmouth sex shop, and find out why the internal gases of King Henry VIII caused him to literally pop inside his own coffin. --- 00:00 – Gary's Basement Eggs and the Over-Tight Costume Crisis 00:19 – Formulating a £30 "Corned Beef Spam Nut" Kit for Nostalgic Pensioners 03:30 – Licky the Mascot Gives an Extravagant Face-Licking to a Married Woman 05:11 – Turning 50: The 1970s Nuclear Survival Kit Tobacco Tin Lore 06:39 – Waking Up to the Casualty Theme Tune 08:12 – Phoning in the "Angst" Tour and Saving a Life with The Archers 09:51 – Podcasting for "Young" Pensioners and Failing to Sing Like Jeremy Hardy 10:33 – Outsourcing Our Brains to Siri until We Become Sofa Blobs 11:43 – Sarah the AI Bot Summons the Medway Posse and Bigs up Chatham 13:20 – The Maidstone Anthem: Sex Shops, Golden Boots, and Prison Walls 14:40 – High Street Slander 15:22 – Checkers Model Shops and the Measurement Machines of the Golden Boot 16:28 – The Stoned Anagram and Wes Anderson's Secret Mansion in Basted 17:46 – The Caravan-Enthusiast, Naturist, Swinger Sex Shop Dad 18:20 – Sharing the Pre-Streaming Suitcase Bootlegs Like the Original Pornhub 19:22 – Amateur Dramatics as the Comic Fat Girl and Sudden Bereavement at 60 20:21 – Emceeing Jack Skipper's First Ever Jill Edwards Comedy Showcase 21:13 – The Five-Day House of Games Sweep and Facing Social Media Trolls 23:08– ADHD Hyperactivity and the Sussex University Synesthesia Study 26:41 – The 19-Year-Old Brain Connection Realization and 10 Minutes of Stand-Up Material 27:35 – Ad Break: Regency Foods Present Princess Anne Molds and complimentary Cremation 29:19 – Adam Pennington Explains the Desperate Male Heir Mania of the Tudors 30:39 – Holbein Portraits, Breaking the Papacy, and Banishing Catholics From Succession 31:41 – A 400-Pound King Whose Gammy Leg Smelt From Three Rooms Away 32:08 – Jude Law Spraying Feces, Pus, and Blood Perfume All Over the Firebrand Set 32:48 – Illegitimate Lancastrians, Princes in the Tower, and the Game of Thrones War 34:30 – Tenuous Bloodlines: How 78% of Britons Are Descended From William the Conqueror 35:22 – Royal Imposter Syndrome and Beheading the Remaining Plantagenets 36:19 – Whispering Chromosome Irony Into the Beheaded Ear of Anne Boleyn's Legacy 38:00 – Fastidious Manners, Six-Foot-Three Strapping Youth, and Monastic Dissolution 39:33 – Hiring a Sword Executioner Before Anne Boleyn Even Went to Trial 40:27 – Heavy Petting in the Mid-50s: Catherine Howard and Jane Boleyn's Shared Fate 41:25 – Knighting a Sirloin Steak and Hanging Out at Hever Castle 42:26 – Ulcerated Leg Pain and Popping Open via Internal Coffin Gases 44:08– Sarcophagus Re-Gifting and the 11-Strike Axe Horror of Margaret Pole 45:10– QUIZZITY QUIZ: 53:08 – Gary's Joke Corner 54:57 – Butterfly In Blue Jeans "Angela Barnes" by Wikipedia contributors, used under CC BY-SA 4.0. Derived from the Wikipedia article on Angela Barnes. / This work is licensed under CC BY-SA 4.0. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Meat-Derived Toxins Accelerate Brain Inflammation; Processed Meats Pose Greatest Risk to Brain Health; Meeting Calorie Needs Without Protein Excess; Success Story: Regaining Function After Diet Change; Mucuna Pruriens as a Natural Dopamine Source; Mucuna Water Extract Offers Gentler Delivery; Caution on Switching from Levodopa to Mucuna; Neuroscience Nutrition Foundation's Research Focus; Lewy Bodies and Dementia Risk in Parkinson's; Skullcap Herb Calms and Protects Dopamine Neurons; Resveratrol Clears Lewy Bodies and Boosts Energy; Turmeric Protects Brain and Enhances Motor Skills; Tea Reduces Parkinson's Risk and Lewy Bodies; Inflammatory Foods Linked to Parkinson's Progression #Parkinsons #BrainHealth #NeuroNutrition #HealthTalks

TAKE IT OFF! TAKE IF OFF! We're back. This week, Harry is joined by comedian, television presenter, and incredibly good-looking man Joel Dommett! Harry relives the claustrophobic nightmare of performing inside a giant furry suit on The Masked Singer (which he only did because Joel told him it would be "fun" ), and explains how he almost had a heart attack dressed as a Red Panda. Meanwhile, Joel reminisces about his teenage nu-metal band and the importance of a silent p. Friend of the Vodscarf, Professor Chris Lintott drops by to explain why Venus is an acidic holiday hellhole. 00:09 - Giant Eggs in the Basement 01:15 - Behind the Scenes of The Masked Singer with Red Panda 02:58 - Harry's Secret Vocal Coaching & Professional Singing Defenses 04:10 - The Ridiculous Secrecy: Hoodies, Visors, and Secret Cars 05:06 - The Great Sloth Pronunciation Debate 06:10 - Sixty-One and Dressed as a Red Panda: Harry's Near-Death Experience 07:50 - Human Chemistry vs. Thirsty AI Bots 09:00 - Sarah the AI Bot Welcomes 09:10 - The Last Days of Rome: Joel and Harry Dissect the National TV Awards 10:04 - Trevor McDonald: The Comedy Killer 12:37 - Angela Barnes Thinks Joel Is Too Good-Looking for Comedy 13:58 - Joel's Nu-Metal Days 14:48 - Crowd-Surfing at Your Own Funeral 16:48 - The True Cost of Australia: Extra Camp Logistics 17:28 - Joel's Bristolian Acting Masterclass: Crashing Cars in Casualty 18:36 - Former Doctor Harry Hill Wants a Guest Spot on Holby City 19:34 - Tea, Biscuits, and Private Hospital Pillow Requests 20:34 - Harry's Mum Gets Knocked Down Dressed as a Keyboard 22:36 - Regency Television Presents: Trevor McDonald Live From the Albert Hall 24:33 - Theme of the Week: Venus (with Professor Chris Lintott) 25:48 - Why Venus Is the Absolute Worst Vacation Spot in the Solar System 27:19 - Lazy Astronomy: Stargazing From the Middle of London 27:52 - Active Volcanoes and Being Bored on a Zoom Meeting 28:48 - Sulfuric Acid, Flying Penguins, and the Runaway Greenhouse Effect 31:14 - Venus: The Solar System's Monthly Service Station 33:02 - The Planet of Love: Mythological Names and Diseases 34:32 - The French Balloon Plan & Melted Russian Probes 36:09 - Harry's Dark Baby Joke That Never Lands 37:35 - The Grand Finale: Celebrity Name the Seed! 40:25 - The High-Stakes Guess: Britney Spears on a Chair vs. Joel's Wife 43:27 - Gary's Joke Corner 45:11 - Butterfly in Blue Jeans "Joel Dommett" by Wikipedia contributors, used under CC BY-SA 4.0. Derived from the Wikipedia article on Joel Dommett. / This work is licensed under CC BY-SA 4.0." Learn more about your ad choices. Visit podcastchoices.com/adchoices

In this week's episode of the Podscarf we welcome Welsh comedic force Kiri Pritchard-McLean (who was spotted on a train trying to ignore Harry by aggressively speaking Welsh ) and University of Kent Music Hall expert Oliver Double to the studio for an hour of pure, unadulterated historical bawdiness and skincare science. Things get incredibly weird, incredibly fast. Watch as Kiri tries to navigate an absolute safeguarding nightmare involving Harry's fictional heir, Gary, and his filthy collar , witness Harry deliver his highly detailed skincare routine and we see the return of the ANDY BURNHAM. --- 00:00 – The Danbury Mint x Christian Labuta Flamboyant Shoe Collab 01:09 – The Cardiff-Glasgow Train Stalking Incident 02:59 – Fostering, Permaculture, and the "Angle Grinder" Dating App 04:20 – Licky the Mascot gets way too close to Kiri's hair 05:49 – Chilling Deep Relationships with Chat GPT Therapists 07:09 – The Andy Burnham Dance 08:39 – Sarah the AI Bot offends the entire nation of Wales 09:32 – Dark History: The English Academics and the Block of Wood 10:22 – Sarah's Biographical Slander: "Gloucester Born?!" 11:28 – The Vagaries of Animal Welfare Charities and Indoor Toilets 13:55 – Fart-powered Permaculture and Burning Your Own Effluent 15:23 – Harry's Hyper-Intense 12-Step Korean Skincare Regime 16:38 – The Musty Flannel Incident ("Stop it mum, I can't breathe!") 17:09 – A Plant-Based Crisis: Sarah hands a Vegan a Twix bar 18:20 – Caroline Aherne being naughty in a cab 22:20 – Theme Of The Week: Music Hall 26:40 – Charles Morton's Canterbury Trick and the Shape of the Hackney Empire 27:57 – The Dignitas Reunion Dinner Incident (A Dignitary falls off the stage) 31:23 – Little Titch: Six-fingered Mittens and Big Boot Dancing 33:10 – Royal Variety Scandal: Queen Mary hides from a woman in trousers 34:29 – Sweating on stage with the Spice Girls and Jim Davidson in 1997 35:54 – Fanning Dad with a Kipper: The DNA of Early Stand-up Comedy 38:20 – Mechanical Funnels and the Financial Collapse of Wet Money 41:04 – The Glasgow Empire: Graveyard of English Comics and Fake Fainting 44:22 – John Major's Dad and the Great Music Hall War of 1907 46:04 – Joan Rhodes: Bending Steel, Tearing Phone Books, and Dominating at Scrabble 47:11 – Celebrity Name the Seed! 52:38 – Gary's Joke Corner 55:20 – Butterfly In Blue Jeans "Kiri Pritchard McLean" by Wikipedia contributors, used under CC BY-SA 4.0. Derived from the Wikipedia article on Kiri Pritchard McLean. / This work is licensed under CC BY-SA 4.0." Learn more about your ad choices. Visit podcastchoices.com/adchoices

In this week's episode of the Vodscarf we welcome legendary documentary filmmaker Louis Theroux (after he accidentally walked onto set, why else would he be there?!) and Oxford astrophysicist Professor Chris Lintott to the studio for an hour of pure, unadulterated science and anti-comedy. Things get incredibly weird, incredibly fast. Watch as we attempt to save our nose-diving viewer retention graph by shouting random words at you, dive deep into the tragic family lore of Harry's fictional heir, Gary, and witness Louis Theroux showing he is in fact Harry's number one fan. If you've ever wanted to hear an esteemed Oxford professor explain why aliens might just be a bunch of Venusian penguins standing around in their own poo, listen up. 00:00 – Fixing our terrible viewer retention graph (Kittens! Puppies! Sex!) 02:00 – Licky is a bit keen 03:25 – Gary reveals he is a 12-year-old incel 05:45 – Dark family secrets: Gary's mum is in a secure institution 08:50 – Louis Theroux proves he is a Harry Hill superfan 13:15 – The Bald Cap Incident 15:40 – Sarah the AI Bot brings out the Twix bars 18:00 – An impromptu musical tribute to Catford 26:50 – The Theroux Bunch theme song 28:00 – Space Talk: Do aliens look like us? (The Theroux-Hill Theory) 36:10 – Professor Chris Lintott exposes Venusian poop penguins 38:25 – Louis met a man who chopped up 10 aliens 41:28 – Game Time: "What is the Velcro Singing?!" 43:28 – Gary's Joke Corner (Louis tells a highly inappropriate joke) 45:15 – Butterfly In Blue Jeans "Louis Theroux" by Wikipedia contributors, used under CC BY-SA 4.0. Derived from the Wikipedia article on Louis Theroux. / This work is licensed under CC BY-SA 4.0. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Alex Horne - comedian, creator, and the middle of three boys from Chichester - joins Harry to talk about loving school, his hard-hitting Goldsmiths student documentary about urban foxes, and whether the word "meat" was meant as a pun in Harry's new ballad. We also hear about a 24 hour singing challenge that accidentally lasted 25 and three quarter hours, why Alex's wife Rachel is in charge of his private pension, and a highly questionable "life swap" idea based entirely on dishwasher ethics. Architectural historian and seaside culture expert Dr. Kathryn Ferry stops by to celebrate Scarborough's 400th anniversary and answer the questions that matter - did King George III actually say "bugger Bognor"? Why do pleasure piers have a habit of burning down? And would you buy the Brighton Palace Pier with Harry? Hit subscribe so you never miss an episode! Timestamps 00:00 – Welcome to the Hill Show! 00:36 – A Love Song for Ham 01:36 – Meet Alex Horne! 02:28 – Licky the Mascot 03:45 – The Cheshire United Pig Mascot 04:50 – The 25-and-Three-Quarter-Hour Sing-a-thon Error 06:15 – Granola Chaos Backstage at Battersea Power Station 07:18 – Dishwashing Debates & The Wife Swap Idea 10:45 – Sarah the AI Bot Claims She Felt Scammed 12:44 – Is Alex a Musician? (And the Son of a GP) 15:25 – Goldsmiths, Urban Foxes, and a Guaranteed Distinction 16:45 – Seeing Vic and Bob at the Albany Empire 18:45 – Sarah's Breakdown of Alex's Sky News Career 22:20 – Trying to Force "Honk" and "Pratt Digger" into the Dictionary 24:35 – Meeting Ken Dodd & Leaving the Show to Get a Coat 26:34 – Wafer-Thin Ham Product Recall Emergency 28:40 – Taskmaster in the Children's Ward 29:45 – The Traumatic Five-Foot Badger Story 31:04 – Wafer-Thin Ham Preventative Nose Cages 32:34 – The British Seaside ft. Dr. Catherine Ferry 35:05 – Scarborough's 400th Anniversary & The Mineral Spring 37:32 – Steamers, Trains, and Jane Austen Styles 38:45 – King George V and the Truth About "Bugger Bognor" 39:15 – Victorians, Bank Holidays, and the Invention of the Holiday 40:00 – The Very First Pleasure Pier on the Isle of Wight 42:50 – Buying Brighton Pier & The Fire Overheads 44:54 – Pebble Ridges, Mud, and Catherine's Postcard Book 47:45 – Name the Celebrity Seed! 52:30 – Gary's Joke Corner: Identity Politics 54:55 – Animals in Clothes Outro Song "Alex Horne" by Wikipedia contributors, used under CC BY-SA 4.0. Derived from the Wikipedia article on Alex Horne. / This work is licensed under CC BY-SA 4.0. Learn more about your ad choices. Visit podcastchoices.com/adchoices

In our ongoing series Above All Else, Grant Clark turns to the seventh and most misunderstood of the deadly sins: sloth. Far from simple laziness, sloth -- or acedia -- is a spiritual apathy and quiet resistance to Jesus that can live just as easily in the heart of the overachiever as in the one on the couch."Acedia is ultimately a failure of love. It's a place of apathy toward life and a kind of spiritual boredom... Whether midday, midlife, halftime or halfway through a big project, we're tempted to give in, give up or distract ourselves. Acedia tempts us to abandon the life we have for some imagined better option somewhere else -- as in 'anywhere but here'! Acedia can also be the temptation to live our lives in imagined fantasies of what might be rather than living in the gift of what is." - Alan Fadling (An Unhurried Life)What is acedia?- The Cambridge Dictionary defines sloth as "an unwillingness to work or to make any effort" -- but the biblical concept runs far deeper- Derived from the Greek a ("not") + keedos ("to care") -- acedia is a failure of love, a resistance to the transformation God is calling us into- Pope John Paul II defined acedia as "a sadness arising from the fact that the good is difficult"- It is not just laziness -- it is a selective laziness that can look like overwork, busyness, and productivity while neglecting the most important thingWhat does acedia look like?- The story of Mary and Martha (Luke 10:38-42): Martha was productive and active, but distracted from the one thing necessary -- attentiveness to Jesus- "Acedia is 'a restlessness that entices us to pursue everything but our most important duties. Acedia distracts. It makes us lazy and sluggish toward our spiritual and practical responsibilities. It is a selective laziness that makes everything else appealing.'" - John Cassian- "Slothful people are not only found lying around on couches or beds. They are often found in the gym every morning at 5:00 A.M., leading large organizations and companies, writing books, achieving goals, and even working hundred-hour weeks. Yes, the same sin can be at work in the heart of the person glued to the TV and the person who does not have time for TV. Christian thinkers have always seen links between laziness and overwork, though the definition of sloth has morphed through the years." - Trent Casto (The Death of the Deadly Sins)- Sloth wears many masks: variety-seeking, escapism, distraction, commitment-phobia, procrastination, and never finishing what we start- The "noonday demon" of the Desert Fathers -- the midday restlessness that whispers anywhere but here- Delayed obedience: like Augustine's prayer, "Lord, give me chastity and self-control -- but not yet"- Acedia is avoiding the responsibilities that loving God and loving neighbor require - Trent CastoFrom sloth to zeal (Romans 12:11)- "Do not be slothful in zeal. Be fervent in spirit. Serve the Lord." (ESV) / "Do not lack diligence in zeal. Be fervent in spirit. Serve the Lord." (CSB)- Zeal = earnest commitment with haste and diligence; fervent = to boil, to burn -- a passion for Jesus- The word diligent in Latin (diligere) means "to love" -- to be diligent in zeal is to love- "Look at the intensity in this verse. The Christian life is neither cold nor indifferent... We face many temptations to be passive or lazy today. So let's heed this word: live on fire for Christ! And let's see that God is gracious in giving us such a command. He knows our frames. He knows our passions can cool. So he exhorts us in love. I believe every Christian in a privileged part of the world must always ask, 'Do I love comfort too much? Has it become an idol? Has it caused me to shrink back from passionate service to the Lord Jesus?'" - Tony Merida- "Since acedia is a failure to appreciate the gifts of the present moment or the present season, the classic remedy for acedia has always been to abide in the good relationships and to engage in the good work before us." - Alan Fadling- Practical response: (1) Obey straight away -- identify and repent of any area of delayed obedience; (2) Abide -- stay where God has placed you, persevere in the ordinary, and trust that God is at workVerses- Proverbs 4:23- Luke 10:38-42 (CSB)- Luke 10:40- Romans 12:11 (ESV + CSB)- Ephesians 2:8-10- Hebrews (for the joy set before him, he endured the cross)- Psalm 72

Summary: Hidradenitis Suppurativa (HS) is one of dermatology's most complex and underrecognized conditions and the treatment landscape is changing fast. In this episode, Dr. Faranak Kamangar sits down with Dr. Hadar Lev-tov, Associate Professor at the University of Miami, Director of the Wound Healing Fellowship, and Immediate Past President of the Hidradenitis Suppurativa Foundation, for a rapid-fire review of everything happening in the HS world right now. Dr. Lev-tov covers the currently approved therapies, the exciting drugs moving through Phase 3 trials, and the groundbreaking science linking microplastics to HS inflammation. He also shares his candid take on GLP-1s in HS management and what the future of dermatology looks like when treatments work so well that doctors can finally focus on the whole patient. Whether you're a resident just learning HS or a seasoned dermatologist trying to keep up with a fire-hose pipeline, this one is for you. Topics Covered: - Approved HS biologics: bimekizumab, secukinumab, adalimumab & biosimilars - Off-label use of infliximab (IV and subcutaneous) in severe HS - Phase 3 pipeline: remibrutinib, povorcitinib, sonelokimab (nanobodies) - CAR T-cell therapy and the possibility of curing inflammatory skin disease - Microplastics, nicastrin, and a landmark Nature Communications paper on HS - GLP-1s in HS: what we know, what we don't, and Dr. Levtov's clinical approach - The HS Foundation's research grants, HS Academy, wound care referral tool, and prior authorization templates - The future of dermatology as lifestyle medicine Resources Mentioned: - https://www.nature.com/articles/s41467-025-65789-7  - HS Foundation website & prior authorization templates: https://www.hs-foundation.org/ - HS Academy (free weekend for residents): https://www.hs-foundation.org/hs-academy - Integrative Dermatology Symposium: integrativedermatologysymposium.com - LearnSkin: learnskin.com This podcast is for educational purposes only and is not a substitute for professional medical advice. Always consult your healthcare provider. Key Takeaways: 1. Validate HS patients the moment they walk in. They've often been dismissed or bounced between providers for years. Simply saying "I understand what you're going through" builds trust immediately and makes the visit more productive. 2. The approved HS treatment arsenal is growing. Bimekizumab and secukinumab (IL-17 inhibitors) are now approved, and adalimumab — including biosimilars — remains a valuable option. Clinical experts are using biosimilars with confidence. 3. Subcutaneous infliximab is an emerging option. Available off-label in the US, new data from French centers shows a protocol: standard IV induction at weeks 0, 2, and 6, then switching to subcutaneous injections every two weeks at week 10 — but only once the patient is in strong remission. 4. Three major drugs are in or completing Phase 3 trials. Remibrutinib (BTK inhibitor, already approved for chronic spontaneous urticaria), povorcitinib (JAK1 inhibitor), and sonelokimab (a nanobody targeting IL-17A and IL-17F) are all reporting promising results and moving toward FDA application. 5. Nanobodies are a technology to watch. Derived from camelid antibody fragments, nanobodies like sonelokimab can be engineered to target multiple pathways simultaneously in a smaller, more modular molecule — expect to see them across dermatology. 6. Half-life extenders could mean one injection per year. Already emerging in psoriasis, these extended-dosing biologics are heading toward HS — a potential game-changer for patient adherence. 7. CAR T-cell therapy may one day cure inflammatory skin disease. Currently being studied in lupus and rheumatoid arthritis, the protocols are becoming more practical, and the technology is edging toward dermatology. 8. Microplastics may potentiate HS inflammation. A Nature Communications paper by Dr. Luis Garza (Hopkins) found that plastic-associated endocrine disruptors block nicastrin in fibroblasts, amplifying HS-related inflammation. This doesn't prove causation, but it reveals a meaningful environmental link — and highlights the underappreciated role of fibroblasts in HS scarring. 9. GLP-1s in HS: promising but not proven as monotherapy. There's no RCT yet. Dr. Levtov's clinical approach: stabilize HS with a biologic first, then consider adding a GLP-1 as part of a comprehensive plan that includes diet and resistance training. He has seen outcomes go both ways. 10. The HS Foundation is an underutilized resource. Their website offers a clinic finder, wound care referral service, prior authorization templates (one-click Word documents), research grants, the HS Academy (free, all-expenses-paid weekend for residents), and career development awards in partnership with the Dermatology Foundation. Chapters: 0:00 – Introduction & Dr. Lev-tov's Background 0:49 – The #1 Clinical Tip for Seeing HS Patients 1:44 – Approved HS Treatments: IL-17 Inhibitors, Adalimumab & Biosimilars 2:40 – Off-Label Infliximab: IV and the New Subcutaneous Protocol 4:21 – Phase 3 Pipeline: Remibrutinib, Povorcitinib & Sonelokimab (Nanobodies) 6:00 – Half-Life Extenders & One-Injection-Per-Year Future 7:01 – CAR T-Cell Therapy: Could We Cure Inflammatory Skin Disease? 7:36 – Research Funding & HS Foundation Grants 8:43 – HS Foundation Tools: Prior Auth Templates, Clinic Finder & HS Academy 10:15 – Microplastics, Nicastrin & the Nature Communications Paper 13:22 – What This Means for Fibroblasts and HS Scarring 14:20 – Celebrating Dermatology Science & Clinician-Scientists 15:32 – GLP-1s & HS: What's the Evidence? 17:18 – Dr. Lev-tov's Clinical Approach to GLP-1 Requests 19:06 – The Future of Dermatology: Becoming Lifestyle Doctors 21:28 – The Integrative Dermatology Symposium & LearnSkin Certificate Program 22:50 – Closing Remarks

Commentary by Dr. Jian'an Wang.

Commentary by Dr. Jian'an Wang.

Bridget Christie — comedian, writer, and the youngest of nine siblings from Gloucester — joins Harry to talk about leaving school at 15 with basically no qualifications, getting a four-star review in The Times, and why she keeps forgetting the plots of books she's just read. We also hear about a deeply chaotic Celebrity Millionaire with Al Murray, Chris Tarrant marching down a corridor with a ghetto blaster playing "Alice Who The F**k Is Alice," and Bridget's decision to commemorate all of this by painting him in the nude.Plus: Battersea Dogs Home's canine behaviourist Beth Bushkid brings in Pancake the pug (brother: Dumpling) to answer the questions that matter — can you teach your dog to go to bed when a fox turns up? Are dogs psychic? And what is a dog? Bridget also becomes the first person in the show's history to do something correctly. Hit subscribe so you never miss an episode! Bridget Christie" by Wikipedia contributors, used under CC BY-SA 4.0. Derived from the Wikipedia article on Bridget Christie. / This work is licensed under CC BY-SA 4.0. Learn more about your ad choices. Visit podcastchoices.com/adchoices

A different kind of bar scene has grown across the Bay Area since the pandemic: listening bars. Derived from a tradition that took off in 1930s Tokyo, they're businesses that play high-fidelity music from vintage speakers. Reporter Nava Rawls went to find out if these special places made for listening are one-hit wonders… or here to stay.  

The battlefield has changed — and according to Dr. Scott Perez, most people still don't fully understand how much pressure the human body is under in today's world. In this powerful conversation with Michael Jaco, Dr. Perez explains why modern life is creating an environment filled with chronic stress, toxic overload, weakened immunity, inflammation, and constant physical and psychological strain. From environmental exposure and poor nutrition to increasing biological stressors, many people are running on depleted systems without even realizing it. That's why the focus of this episode is simple:

Adam Hills, the biggest comedian to come out of the home of the Sydney Tramway Museum joins Harry to talk about everything from surviving a five-hour bladder-testing royal ceremony to why AI comedy routines are getting a little *too* good for comfort.We also take a deep, chaotic dive into British history with archaeologist Dr. Erin Lloyd-Jones to uncover the truth about William Wallace. Did he actually wear a kilt? Did he paint his face blue like Mel Gibson? And what exactly is a "sticky end"? (Warning: it involves a lot of tar ). Plus, introducing yet ANOTHER new game, "What is the Velcro Singing?" and check in with Gary's Joke Corner. "Adam Hills" by Wikipedia contributors, used under CC BY-SA 4.0. Derived from the Wikipedia article on Adam Hills. / This work is licensed under CC BY-SA 4.0. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Henning Wehn, Deutschlands größter Lacher, ist diese Woche bei Harry zu Gast. Außerdem erfahren wir alles über Uhren von dem Denkmalpfleger Alex Jeffrey. Henning Wehn, Germany's biggest laugher joins Harry this week. We're learning all about Clocks with conservationist, Alex Jeffrey. "Henning Wehn" by Wikipedia contributors, used under CC BY-SA 4.0. Derived from the Wikipedia article on Henning Wehn. / This work is licensed under CC BY-SA 4.0. Learn more about your ad choices. Visit podcastchoices.com/adchoices

In our latest episode, Steve Palmer and the team break down a headline-grabbing legal situation involving Nick Fuentes and the boundaries of self-defense at home.Key Topics CoveredDoxing & the Law: What is doxing, and is it a crime? We touch on the consequences and legal gray areas that follow sharing someone's private information online.Reasonable vs. Unreasonable Force: Steve Palmer discusses what the law actually permits when someone shows up at your door, and where Fuentes may have crossed the line (04:00).Deferred Prosecution & Diversion Explained: Confused about the difference between these alternatives to prosecution? Steve Palmer clearly outlines how these programs work, using Ohio law as an example (09:08 and 11:16).Civil Lawsuits After Criminal Cases: Even after criminal charges are resolved, civil cases can follow. We discuss damages, nuisance value, and when it makes sense to settle (19:20).Creative Lawyering: Sometimes, standard legal options aren't available, and good lawyers get creative to resolve cases favorably for their clients (29:40).What You'll LearnWhat is doxing (or doxxing)? - It is the act of publicly revealing private, personally identifiable information about someone online without their consent, often with malicious intent. Derived from "dropping docs (documents)," it aims to harass, intimidate, shame, or threaten victims by exposing details like home addresses, phone numbers, or private emails.The tricky thresholds for self-defense (and why simply being annoyed isn't enough).Why an apology or anger management class isn't always as straightforward as it sounds.The meaning of “nuisance value” and why some lawsuits settle regardless of their merits.Did You Know?Fuentes' case led to a deferred prosecution agreement that included restitution for the alleged victim's phone, an apology, anger management, and 75 hours of community service (13:28). Yet, the aftermath shows that legal issues often spill into civil court—where money, not just justice, takes the spotlight.Key Moments03:38 Dealing with public scrutiny09:08 Understanding diversion programs10:30 Understanding Ohio's diversion programs14:53 Using private counseling options18:50 Explaining assault and battery20:58 Discussing emotional distress in lawsuits24:25 Questioning injury severity27:27 Intervention in lieu of conviction29:40 Creative case resolution strategiesSubmit your questions to www.lawyertalkpodcast.com.Recorded at Channel 511.Stephen E. Palmer, Esq. has been practicing criminal defense almost exclusively since 1995. He has represented people in federal, state, and local courts in Ohio and elsewhere.Though he focuses on all areas of criminal defense, he particularly enjoys complex cases in state and federal courts.He has unique experience handling and assembling top defense teams of attorneys and experts in cases involving allegations of child abuse (false sexual allegations, false physical abuse allegations), complex scientific cases involving allegations of DUI and vehicular homicide cases with blood alcohol tests, and any other criminal cases that demand jury trial experience.Steve has unique experience handling numerous high publicity cases that have garnered national attention.For more information about Steve and his law firm, visit Palmer Legal Defense. Copyright 2026 Stephen E. Palmer - Attorney At LawMentioned in this episode:Circle 270 Media Podcast ConsultantsCircle 270 Media® is a podcast consulting firm based in Columbus, Ohio, specializing in helping businesses develop, launch, and optimize podcasts as part of their marketing strategy. The firm emphasizes the importance of storytelling through podcasting to differentiate businesses and engage with their audiences effectively. www.circle270media.com

WE'RE BACK and Mummy Joe Lycett is in the studio for more of what you've come to know and love. Including a new AND exciting upgrade to Name The Seed. "Joe Lycett" by Wikipedia contributors, used under CC BY-SA 4.0. Derived from the Wikipedia article on Joe Lycett. / This work is licensed under CC BY-SA 4.0. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Send us Fan MailWhat Does “Opus” Mean in Classical Music?What does “opus” mean when you see it in a classical music title?In this episode of The Classical Music Minute, we explore the meaning behind this common musical term. Derived from the Latin word for “work,” opus numbers are used to catalogue and organize a composer's compositions.Typically assigned in order of publication rather than composition, opus numbers help distinguish one piece from another—especially when composers wrote many works in the same genre.For example, Beethoven's Moonlight Sonata is listed as Op. 27, No. 2, indicating its place within a published set of works.While not all composers used opus numbers consistently, the term remains a helpful way to navigate the vast world of classical music.In just sixty seconds, discover how one simple word helps organize centuries of musical creativity.Fun FactSome composers, including Frédéric Chopin, were very selective about which works received opus numbers—often assigning them only to pieces they felt were worthy of publication, leaving many compositions unpublished or without a number.About The Classical Music MinuteThe Classical Music Minute is a short podcast exploring fascinating stories, quirky history, and surprising facts from the world of classical music—all in about sixty seconds.Each episode offers a quick and entertaining glimpse into composers, masterpieces, musical traditions, and the curious moments that shaped music history.You can also read the written versions of these episodes on Substack, where they're published as short articles delivered directly to subscribers.About Steven, HostSteven Hobé is a Canadian composer and actor based in Toronto and a member of the Canadian League of Composers. He is the creator and host of The Classical Music Minute, a series devoted to making classical music history engaging, surprising, and accessible.Join me on Substack

A new week means new questions! Hope you have fun with these!Jonathan Demme won his first and only Oscar for directing which film?What is the only word that is also a prefix of measurement in the NATO phonetic alphabet?Which gulf gave its name to the 1990 Gulf War?A hautboy is an archaic form of what woodwind instrument?Before becoming President, George W. Bush owned which MLB Franchise?Derived from the Greek word for 'gold or gold-colored', what name is given to the the hard, protective pupal stage of a butterfly?What book upset Theodore Roosevelt so much he pushed congress to pass the Meat Inspection Act?Which action involving enzymes produces beer and cheese and is also called zymosis?Fittingly, a Boston University professor once fooled the Associated Press by inventing a fake origin of April Fools' Day, claiming which Roman emperor created a “day of jollity” after a jester named Kugel was made king for a day?Morgan Freeman has played Detective Alex cross in two movies, name them, five points for each correct answerWhat was the first game from marvel made by capcom?The Palacio Libertad and the Teatro Colón are both located in which South American capital city?How many different ways can the letter combination "-ough" be pronounced in the English language (British & American)?Which cranial nerve connects the brain with the heart, lungs, and digestive tract?In Dungeons and Dragons, a number measuring the amount of damage a creature, character, or object can take before being killed, disabled or destroyed is called what?Which former Seattle Reign FC player and former Seattle Storm WNBA player recently announced their breakup?MusicHot Swing, Fast Talkin, Bass Walker, Dances and Dames, Ambush by Kevin MacLeod (incompetech.com)Licensed under Creative Commons: By Attribution 3.0 http://creativecommons.org/licenses/by/3.0/Don't forget to follow us on social media:Patreon – patreon.com/quizbang – Please consider supporting us on Patreon. Check out our fun extras for patrons and help us keep this podcast going. We appreciate any level of support!Website – quizbangpod.com Check out our website, it will have all the links for social media that you need and while you're there, why not go to the contact us page and submit a question!Facebook – @quizbangpodcast – we post episode links and silly lego pictures to go with our trivia questions. Enjoy the silly picture and give your best guess, we will respond to your answer the next day to give everyone a chance to guess.Instagram – Quiz Quiz Bang Bang (quizquizbangbang), we post silly lego pictures to go with our trivia questions. Enjoy the silly picture and give your best guess, we will respond to your answer the next day to give everyone a chance to guess.Twitter – @quizbangpod We want to start a fun community for our fellow trivia lovers. If you hear/think of a fun or challenging trivia question, post it to our twitter feed and we will repost it so everyone can take a stab it. Come for the trivia – stay for the trivia.Ko-Fi – ko-fi.com/quizbangpod – Keep that sweet caffeine running through our body with a Ko-Fi, power us through a late night of fact checking and editing!Quiz, trivia, games, pub+trivia, pub+quiz, competition, education, comedy

What if AI isn't just a tool to plug into your business — but a reason to redesign the entire thing? In this episode, Jeff Mains sits down with Steven Wunker, managing director of New Markets Advisors and bestselling author of AI and the Octopus Organization: Building the Super Intelligent Firm. Steven has been working in AI since 2012 and has advised dozens of Fortune 500 companies on how to unlock real growth through transformation — not just optimization.Steven challenges the "AI magic dust" approach most companies default to — sprinkling AI on top of existing workflows for marginal gains — and makes the case for something far more powerful: using AI to take over entire classes of tasks, redistribute decision-making to the front lines, and redesign how organizations actually work. Whether you're a SaaS founder thinking about your product roadmap or a leader rethinking your org structure, this episode will challenge you to think way bigger.Key Takeaways4:13 — AI is the biggest shift of our lifetimes — bigger than smartphones Steve has been in AI since 2012 and helped launch one of the first smartphones in 1999. He says this is still bigger — not just in breadth of adoption, but in depth: changing strategies, org structures, and roles within companies.7:14 — Stop using AI as "magic dust" Sprinkling AI on top of existing workflows only yields marginal gains. The real transformation happens when AI takes over entire tasks that humans won't do (too tedious), shouldn't do (not the best use of their skills), or can't do (too high volume). That's when organizations must fundamentally rethink how work gets done.9:55 — The Octopus Organization: distributed intelligence in action The octopus has nine brains — one central brain and one in each arm. Each arm can sense, think, and act independently while remaining contextually aware of the whole. That biological model is the blueprint for how AI-powered organizations should be structured: parallel execution, distributed decision-making, and strategic focus at the center.11:25 — Why authority hasn't truly been devolved — and how AI finally changes that For 40 years, leaders have talked about flattening orgs and devolving decision-making. It hasn't happened for two reasons: humans resist giving up authority, and front-line workers have lacked the contextual awareness to make good autonomous decisions. AI solves the second problem — and also gives leaders visibility to veto in near real-time rather than always having to pre-approve.16:48 — Map the "work chart," not the org chart Microsoft calls it the "work chart" — how work actually flows through the organization, cross-functionally, in reality. That's what needs to be mapped and redesigned. Layering AI onto the org chart misses the point entirely. Change happens workflow by workflow, tranche by tranche.26:29 — Three questions every leader must answer right nowHow does the competitive landscape change? (Include DIY and AI-native startups)What makes you special in an AI world?How do you get work done — what behaviors, culture, and structure do you need?32:19 — Everyone in management is now a change manager It doesn't matter how technical your role is — if you have people reporting to you, you must become a change manager. That skill can no longer be confined to a C-suite priesthood. Psychological safety for AI adoption and rethinking how good work is incentivized are critical.32:58 — The LUCK framework for strategic serendipity Derived from workforce survey research, four patterns that separate successful AI adopters:L — Leverage help (stay connected, workflows are increasingly cross-functional)U — Unexpected connections (be open to signals outside the average case)C — Control chaos (build systems to absorb the disruption coming)K — Know what's missing (AI is only as good as its data; humans must fill the gaps)34:57 — Don't chase glamorous AI use cases first IBM's Watson failed spectacularly by targeting cancer diagnoses — the world's best oncologists didn't need it. The win? Recording doctor-patient conversations so doctors can actually practice medicine instead of typing. Low risk, high utility, high return. Start there.38:05 — The most valuable AI use cases are unglamorous Things humans won't do: take notes after every meeting and distribute them. Things humans shouldn't do: type during patient consultations. Things humans can't do: transcribe and summarize 40 simultaneous three-person breakout groups and track individual commitments. AI can do all of this — none of it is flashy, all of it is high-value.28:10 — Build in AI optionality from the start Upwork re-engineered their stack with an AI optionality layer — flexible to swap between small LLMs, large LLMs, agents, or other AI systems. You can't predict where AI goes. Build optionality in. Don't make bespoke bets you can't unwind.Tweetable Quotes"AI has this ability to take over certain tasks entirely — things humans wouldn't do, shouldn't do, or simply can't do at scale. That's when it gets truly transformative." — Steven Wunker"We've been talking about devolving authority and de-siloing organizations since 'In Search of Excellence' in the 1980s. It just hasn't happened. AI finally changes the equation." — Steven Wunker"The octopus is 300 million years old — 70 million years older than the dinosaurs — and it has survived because it is so darn adaptable. We need to be like that." — Steven Wunker"AI magic dust — sprinkling it on top of what you're currently doing — will get you marginal improvements. That's nice. But it won't fundamentally change how organizations work." — Steven Wunker"Don't be Adobe in the face of Figma. That has already played out. It would be very easy for that to play out again in innumerable SaaS markets unless we think transformatively." — Steven Wunker"Every person in any management position is now a change manager. It doesn't matter how specialized your technical skill is." — Steven Wunker"Features are only as good as their adoption." — Steven Wunker"AI is only as good as the data that's in it — so it's the role of the human to think about what's NOT in that AI system that needs to complete the picture." — Steven WunkerSaaS Leadership Lessons1. Redesign the work, don't just automate it. The companies that win with AI aren't the ones that add AI features — they're the ones that fundamentally rethink how work flows through the organization. Map your "work chart" (how work actually happens cross-functionally) and redesign it workflow by workflow. Layering AI on your existing org chart is the surest path to becoming the next Kmart.2. Your installed base is an asset — but only if you act transformatively. Existing SaaS companies have something AI startups don't: data, customer relationships, and deep domain context. That is an enormous advantage — but only if you think transformatively. AI-native disruptors are watching your market. Your data moat only protects you if you use it to reimagine what you build, not just improve what you have.3. Prioritize low-risk, high-utility AI use cases first. Resist the temptation to prove what AI can do with your most complex, high-stakes problem. Start where the utility is obvious and the risk is low. Prove value there. Build trust with customers and your team. Then expand. IBM's Watson at MD Anderson is a $62M cautionary tale. The doctor who gets to practice medicine instead of typing is the win.4. Build optionality into your AI architecture. You cannot predict where AI capabilities are heading. Large models, small models, agents, new paradigms — the landscape is shifting too fast to make permanent bets. Build your product and internal systems with an optionality layer that stays flexible. Businesses that hard-code their AI assumptions will face expensive rebuilds. Those who build for adaptability will compound their advantage.5. Transform your go-to-market alongside your product. AI transformation isn't just a product problem — it's a sales, marketing, and customer success problem. The companies that win aren't just selling software; they're selling a changed way of getting something done. That means customer success becomes more important, not less. Sales cycles involve more change management. Proving economic value requires new evidence. Think Workfront, not the feature-obsessed competitor it acquired.6. Make change management everyone's job. The old model — change management as a C-suite discipline — is dead. In an AI-first organization, every manager at every level must develop the skills to lead people through uncertainty, redesign workflows, and create psychological safety for new ways of working. If you're building or leading a SaaS company, start developing these muscles now — in your leaders, your managers, and yourself.Guest Resourcesswunker@newmarketsadvisors.comBook: AI and the Octopus Organization: Building the Super Intelligent Firm — Available on Amazon in all formats (print, ebook, audio)Book Website:

AP correspondent Julie Walker reports the Iran war could drive up costs for petroleum-derived products like clothes and crayons

"Envy causes the body of Christ to attack itself by viewing a brother's blessing as a personal offense."Welcome to week two of our series, The Hygiene of My Heart. This week, Charlie Grimes explores the deceptive pathogen of Envy—the "auto-immune disorder of the soul." Just as a physical illness can cause the body to turn on its own healthy tissue, envy causes us to see a "neighbor" as an "enemy" and a brother's success as our own failure.In this message, we examine:The Pathogen of Perspective: How looking "sideways" at others blinds us to God's goodness in our own lives.The Warning Signs: Recognizing the "downcast face" and the "silent resentment" that rots the bones.The Cain and Abel Case Study: Understanding how comparison can lead to a total systemic collapse of our relationships.The Hygiene Protocol: Practical "antibiotics" for the heart, including specific confession, the "Vitamin C" of contentment, and the exercise of celebration.Stop measuring your "field" against your brother's "altar." Join us as we ask the Great Physician to reset our spiritual immune systems and replace the bitterness of comparison with the soundness of contentment.Scripture References:Galatians 5:25–26Genesis 4:1–8Matthew 20:15Proverbs 14:30About This Series:The Hygiene of My Heart is an eight-week journey into what it takes to get our hearts clean and keep them clean. Derived from the Greek word Hygies, we are seeking to be "sound, healthy, and whole" in our spiritual walk.

Today on The Stacks, we're joined by the 24th Poet Laureate of the US, Ada Limón, to discuss her 11th book, Against Breaking: On the Power of Poetry. Derived from her final lecture as poet laureate, this book explores poetry's profound ability to heal, inspire, connect, and remind us of our shared humanity. We talk about the things poetry can do that prose cannot, how to approach poems you don't like, and what came after her tenure as the poet laureate.The Stacks Book Club pick for April is Room Swept Home by Remica Bingham-Risher. We'll be discussing the book with Mahogany L. Browne on Wednesday, April 29.You can find everything we discuss on today's show on The Stacks website: https://www.thestackspodcast.com/2026/4/15/ep-420-ada-limonConnect with Ada: Website | InstagramConnect with The Stacks: Instagram | Threads | Shop | Patreon | Goodreads | Substack | Youtube | SubscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The state of Missouri is suing a Missouri-based manufacturer of the 7-OH variety of kratom. Derived from plants, kratom is drawing increased scrutiny and concern. The products are widely sold in gas stations in St. Louis and across the state. We talk with PreventEd Executive Director Jenny Armbruster about kratom, the difference between kratom and 7-OH, why people are becoming addicted, and what educators and advocates are hearing about the substance from users.

On this episode, researchers Caitlin Howell and Mehdi Tajvidi from the University of Maine join the show to discuss their research in developing a fully bio-derived composite coating that is grown, not manufactured. By combining edible fungal mycelium with cellulose nanofibrils, they have developed a barrier coating that can be formed directly on paper and textiles through a low-energy process. The […] The post Bio-Derived Barrier Coatings: A New Frontier in Sustainable Composites first appeared on Composites Weekly. The post Bio-Derived Barrier Coatings: A New Frontier in Sustainable Composites appeared first on Composites Weekly.

High stakes in Texas as cannabis businesses file suit over a new statewide ban on smokable hemp.This year's midterm elections signal the biggest turnover in recent memory and Texas is part of that trend. The Texas Newsroom’s Blaise Gainey on what’s behind this changing of the guard.Despite a tenuous ceasefire with Iran, tech expert Omar […] The post Lawsuit challenges Texas crackdown on hemp-derived products appeared first on KUT & KUTX Studios -- Podcasts.

In this episode, Molecular Therapy Editor-in-Chief Dr. Joseph Glorioso and Dr. Rita Perlingeiro (University of Minnesota) will discuss an article recently published in Molecular Therapy titled, “Preclinical quality, safety, and efficacy of a CGMP iPSC-derived myogenic progenitor product for the treatment of muscular dystrophies.” Music: 'Electric Dreams' by Scott Buckley - released under CC-BY 4.0. www.scottbuckley.com.auShow your support for ASGCT!: https://asgct.org/membership/donateSee omnystudio.com/listener for privacy information.

Comparison of a Hands-Free, Fully Automated Segmentation Angiography-Derived Fractional Flow Reserve, X1-FFR, With Invasive Wire-based Hyperemic FFR

What if a drug could kill cancer cells broadly, spare the immune system and then train it to keep fighting, without triggering resistance? That's the promise behind the ELANE pathway, a mechanism discovered not from a hypothesis but from studying fundamental biology in patients. In this episode of the In Vivo Podcast, Court Turner, CEO and co-founder of Onchilles Pharma, and Lev Becker, CSO and scientific founder, discuss how a neutrophil elastase-based mechanism is being translated into N17350, a first-in-class intratumoral agent targeting solid tumours including head and neck, skin and breast cancers. With $40m raised, GMP manufacturing of thousands of clinical doses completed, a US IND approved, and a first-in-human study underway in Australia, Onchilles is moving from "stubborn optimism" to clinical execution. Court and Lev discuss the dual mechanism that sets N17350 apart from both traditional chemotherapy and immunotherapy, why histone H1 functions as a universal tumour vulnerability rather than a conventional biomarker, and how they're thinking about combinations, partnering and the eventual value story for payers.

It's a batch of great questions from the Crowdpurr library! This epsiode's topic: CUTS OF MEAT for Patreon Subscriber Nathan Stenstrom Host your own amazing quiz nights and bingo shows with Crowdpurr! New customers can get 25% off their first month on any upgraded plan and 10% off any annual plan using code BUDDS. Check it all out at www.crowdpurr.com/budds Fact of the Day: HitchBot was a hitchhiking robot that relied on the kindness of strangers to travel the world. It successfully hitchhiked across Canada, Germany, and the Netherlands, but while attempting to hitchhike across the United States, it was found with its head and arms ripped off in Philadelphia. Triple Connections: Flower, Nail, River THE FIRST TRIVIA QUESTION STARTS AT 02:22 SUPPORT THE SHOW MONTHLY, LISTEN AD-FREE FOR JUST $1 A MONTH: www.Patreon.com/TriviaWithBudds INSTANT DOWNLOAD DIGITAL TRIVIA GAMES ON ETSY, GRAB ONE NOW!  GET A CUSTOM EPISODE FOR YOUR LOVED ONES:  Email ryanbudds@gmail.com Theme song by www.soundcloud.com/Frawsty Bed Music:  "Laser Groove" Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 4.0 License http://creativecommons.org/licenses/by/4.0/ http://TriviaWithBudds.com http://Facebook.com/TriviaWithBudds http://Instagram.com/ryanbudds Book a party, corporate event, or fundraiser anytime by emailing ryanbudds@gmail.com or use the contact form here: https://www.triviawithbudds.com/contact SPECIAL THANKS TO ALL MY AMAZING PATREON SUBSCRIBERS, INCLUDING:   Samantha Wheeler Mark Kloppenburg Alan Kreisel Rich Sommer Joe Heiman Waqas Ali Logan Booker Bringeka Sam Nathan Stenstrom Brooks Martin Robyn Price Gee Brian Clough Lauren Schuette Evan Lemons AnneMarie Mattacchione Yves Bouyssounouse Kenny Zail York yates Gay Geek Fabulous Mollie Dominic Nathalie Avelar Natasha raina leslie gerhardt Diane White Youngblood Trophy Husband Trivia Lynnette Keel Lillian Campbell Jerry Loven Jamie Greig Jeremy Yoder Adam Jacoby rondell Adam Suzan Tiffany Poplin Bill Bavar Sarah Daniel Hoisington Keith Martin Sue First Steve Hoeker Jessica Allen Lauren Glassman Brian Williams Brett Livaudais Linda Elswick Carter A. Fourqurean Justly Maya Brandon Lavin Kathy McHale Chuck Nealen Courtney French Nikki Long Mark Zarate Laura Palmer  JT Dean Bratton Kristy Erin Burgess Trenton Sullivan Jen and Nic Michael Redman Timothy Heavner Jeff Foust Richard Lefdal Myles Bagby Jenna Leatherman Vernon Heagy Albert Thomas Kimberly Brown Tracy Oldaker Sara Zimmerman Madeleine Garvey Jenni Yetter Patrick Leahy Dillon Enderby James Brown Christy Shipley Clayton Polizzi Alexander Calder Ricky Carney Paul McLaughlin Willy Powell Robert Casey Matthew Frost Brian Salyer Greg Bristow Megan Donnelly Jim Fields Mo Martinez Luke Mckay Simon Time Feana Nevel

This episode explores an exciting new way the immune system can be supported using tiny messengers released by natural killer immune cells. These messengers help the body's built-in defense system better spot and remove harmful or worn-out "zombie" cells that drive inflammation and speed up aging. The core idea is simple: help the immune system do its job more effectively, without harming healthy cells. It's cutting-edge science explained in plain language, with big implications for long-term health and resilience.   Key Takeaways To Tune In For: (06:31) – NK Cell Exosomes: Tumor Agnostic Action (12:18) – Risks and Personalized Treatment (17:21) – Integrative Cancer Care and Oncology (21:13) – Patient Selection and Exosome Scarcity (24:44) – Enhancing Treatment: Diet, Hormesis, and Supplements (29:28) – Ongoing Care and Future Applications   Resources talked about in this episode: Websites: https://recellebrate.com/   Social media handles: IG TikTok YouTube LinkedIn  

Extractivism—exploiting the earth for resources—has long driven racial capitalism and colonialism. And yet, how does extractivism operate in a world where ecological and humanitarian sensibilities are unprecedentedly widespread? Eray Çaylı argues it does so by mobilizing these sensibilities in new ways. Extractivism is no longer only about moving the earth—displacing peoples, fossils, minerals, and waters—but also leaving those who witness this violent displacement sentimentally moved. Earthmoving: Extractivism, War, and Visuality in Northern Kurdistan (U Texas Press, 2025) conceptualizes this duality. Derived from Çaylı's years-long work in Northern Kurdistan, home to the world's largest stateless nation—rendered stateless by colonial policies since the nineteenth century—Earthmoving focuses on the 2010s, a decade that began with peace talks between Turkey and the Kurdish liberation movement but ended with war. The decade saw extractivism intensify in the region and images of its harm proliferate across art and media. Together with contemporary artists, Çaylı shows that images challenge extractivism both by making its harm visible and by fostering self-reflexive and reciprocal collaboration that breaks with its valuation of the colonized and the racialized only in quantifiable and marketable terms. Host: Ronay Bakan is a Max Weber Postdoctoral Fellow at European University Institute, in Italy. Her research interests include political geography, mobilization, and counterinsurgency in Southwest Asia and North Africa with a special focus on Northern Kurdistan. She is currently working on her book titled “Counterinsurgent Urbanism: Weaponizing Land and Heritage in Northern Kurdistan.” Email: ronay.bakan@eui.eu Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

Extractivism—exploiting the earth for resources—has long driven racial capitalism and colonialism. And yet, how does extractivism operate in a world where ecological and humanitarian sensibilities are unprecedentedly widespread? Eray Çaylı argues it does so by mobilizing these sensibilities in new ways. Extractivism is no longer only about moving the earth—displacing peoples, fossils, minerals, and waters—but also leaving those who witness this violent displacement sentimentally moved. Earthmoving: Extractivism, War, and Visuality in Northern Kurdistan (U Texas Press, 2025) conceptualizes this duality. Derived from Çaylı's years-long work in Northern Kurdistan, home to the world's largest stateless nation—rendered stateless by colonial policies since the nineteenth century—Earthmoving focuses on the 2010s, a decade that began with peace talks between Turkey and the Kurdish liberation movement but ended with war. The decade saw extractivism intensify in the region and images of its harm proliferate across art and media. Together with contemporary artists, Çaylı shows that images challenge extractivism both by making its harm visible and by fostering self-reflexive and reciprocal collaboration that breaks with its valuation of the colonized and the racialized only in quantifiable and marketable terms. Host: Ronay Bakan is a Max Weber Postdoctoral Fellow at European University Institute, in Italy. Her research interests include political geography, mobilization, and counterinsurgency in Southwest Asia and North Africa with a special focus on Northern Kurdistan. She is currently working on her book titled “Counterinsurgent Urbanism: Weaponizing Land and Heritage in Northern Kurdistan.” Email: ronay.bakan@eui.eu Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/middle-eastern-studies

Extractivism—exploiting the earth for resources—has long driven racial capitalism and colonialism. And yet, how does extractivism operate in a world where ecological and humanitarian sensibilities are unprecedentedly widespread? Eray Çaylı argues it does so by mobilizing these sensibilities in new ways. Extractivism is no longer only about moving the earth—displacing peoples, fossils, minerals, and waters—but also leaving those who witness this violent displacement sentimentally moved. Earthmoving: Extractivism, War, and Visuality in Northern Kurdistan (U Texas Press, 2025) conceptualizes this duality. Derived from Çaylı's years-long work in Northern Kurdistan, home to the world's largest stateless nation—rendered stateless by colonial policies since the nineteenth century—Earthmoving focuses on the 2010s, a decade that began with peace talks between Turkey and the Kurdish liberation movement but ended with war. The decade saw extractivism intensify in the region and images of its harm proliferate across art and media. Together with contemporary artists, Çaylı shows that images challenge extractivism both by making its harm visible and by fostering self-reflexive and reciprocal collaboration that breaks with its valuation of the colonized and the racialized only in quantifiable and marketable terms. Host: Ronay Bakan is a Max Weber Postdoctoral Fellow at European University Institute, in Italy. Her research interests include political geography, mobilization, and counterinsurgency in Southwest Asia and North Africa with a special focus on Northern Kurdistan. She is currently working on her book titled “Counterinsurgent Urbanism: Weaponizing Land and Heritage in Northern Kurdistan.” Email: ronay.bakan@eui.eu Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/critical-theory

Extractivism—exploiting the earth for resources—has long driven racial capitalism and colonialism. And yet, how does extractivism operate in a world where ecological and humanitarian sensibilities are unprecedentedly widespread? Eray Çaylı argues it does so by mobilizing these sensibilities in new ways. Extractivism is no longer only about moving the earth—displacing peoples, fossils, minerals, and waters—but also leaving those who witness this violent displacement sentimentally moved. Earthmoving: Extractivism, War, and Visuality in Northern Kurdistan (U Texas Press, 2025) conceptualizes this duality. Derived from Çaylı's years-long work in Northern Kurdistan, home to the world's largest stateless nation—rendered stateless by colonial policies since the nineteenth century—Earthmoving focuses on the 2010s, a decade that began with peace talks between Turkey and the Kurdish liberation movement but ended with war. The decade saw extractivism intensify in the region and images of its harm proliferate across art and media. Together with contemporary artists, Çaylı shows that images challenge extractivism both by making its harm visible and by fostering self-reflexive and reciprocal collaboration that breaks with its valuation of the colonized and the racialized only in quantifiable and marketable terms. Host: Ronay Bakan is a Max Weber Postdoctoral Fellow at European University Institute, in Italy. Her research interests include political geography, mobilization, and counterinsurgency in Southwest Asia and North Africa with a special focus on Northern Kurdistan. She is currently working on her book titled “Counterinsurgent Urbanism: Weaponizing Land and Heritage in Northern Kurdistan.” Email: ronay.bakan@eui.eu Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/environmental-studies

What if gravity is just entropy in disguise? Professor Erik Verlinde joins me to argue that gravity isn't a fundamental force—it's thermodynamic, emerging from quantum information the way gas pressure emerges from molecules bouncing around. We explore why spacetime may be stitched together by entanglement, and how dark energy and dark matter both pop out automatically without extra particles or parameters. Verlinde explains why the cosmological constant problem is a red herring, and why there may be no final theory of physics. When asked where the universe comes from, his answer is one word: chaos. SUPPORT: - Support me on Substack: https://curtjaimungal.substack.com/subscribe - Support me on Crypto: https://commerce.coinbase.com/checkout/de803625-87d3-4300-ab6d-85d4258834a9 - Support me on PayPal: https://www.paypal.com/donate?hosted_button_id=XUBHNMFXUX5S4 JOIN MY SUBSTACK (Personal Writings): https://curtjaimungal.substack.com LISTEN ON SPOTIFY: https://open.spotify.com/show/4gL14b92xAErofYQA7bU4e TIMESTAMPS: - 00:00:00 - Thermodynamic Gravity and Information - 00:06:35 - Beyond Effective Field Theory - 00:13:08 - Turtles All The Way Down - 00:25:41 - Entropy as a Force - 00:36:31 - Entanglement and Spatial Connectivity - 00:47:31 - Deriving Inertia and F=ma - 00:56:41 - De Sitter Space Challenges - 01:02:01 - Dark Matter and Milgram - 01:11:51 - The Emergence of Time - 01:21:01 - Statistical Gravity Fluctuations - 01:27:01 - Quantum Computational Complexity - 01:36:01 - Physics Intuition and Mentorship - 01:47:31 - Beauty, Garbage, and Chaos LINKS MENTIONED: Papers, books, websites: - https://scholar.google.com/citations?user=Tm64-J0AAAAJ - https://journals.aps.org/prb/pdf/10.1103/PhysRevB.4.3174 - https://arxiv.org/abs/1001.0785 - https://arxiv.org/abs/1611.02269 - https://journals.aps.org/pr/pdf/10.1103/PhysRev.47.777 - https://amazon.com/dp/0486600688?tag=toe08-20 - https://www.nature.com/articles/248030a0 - https://en.wikisource.org/wiki/Translation:The_Field_Equations_of_Gravitation - https://arxiv.org/abs/gr-qc/9504004 - https://arxiv.org/abs/hep-th/0603001 - https://arxiv.org/abs/1005.3035 - https://arxiv.org/abs/hep-th/0106112 - https://arxiv.org/pdf/1408.3203 - https://arxiv.org/abs/1911.02087 - https://arxiv.org/abs/1905.08255 - https://www.ias.edu/sns/events/iaspctspgi-workshop-quantum-aspects-black-holes-and-spacetime - https://amazon.com/dp/0262533413?tag=toe08-20 Videos: - https://youtu.be/HIoviZe14pY - https://youtu.be/X4PdPnQuwjY - https://youtu.be/xZnafO__IZ0 - https://youtu.be/gEK4-XtMwro - https://youtu.be/-BsHh3_vCMQ - https://youtu.be/3mhctWlXyV8 - https://youtu.be/bprxrGaf0Os - https://youtu.be/zNZCa1pVE20 - https://youtu.be/ZUp9x44N3uE - https://youtu.be/2p_Hlm6aCok - https://youtu.be/kUHOoMX4Bqw - https://youtu.be/_yebLXsIdwo - https://youtu.be/Ve_Mpd6dGv8 - https://youtu.be/0YRlQQw0d-4 - https://youtu.be/Bnh-UNrxYZg - https://youtu.be/hF4SAketEHY - https://youtu.be/Iya6tYN37ow - https://youtu.be/0_Px5gbs9i0 - https://youtu.be/gsSJPLX-BTA - https://youtu.be/73IdQGgfxas - https://youtu.be/c8iFtaltX-s Learn more about your ad choices. Visit megaphone.fm/adchoices

Plus, I’m in Punta Cana and spending the night talking to you! Tonight we talk about my trip, watching the Bears Game in a hotel lobby, read your emails, and cover the Holi-Days like National Take the Stairs Day! And as always, I close out the show with Ronda and The Tribune! Thank you to Aaron Brungardt for engineering, mixing, and production expertise, Geoffrey Tice for artwork, Bobby TBD for theme music, and All Things Comedy for their support, production, and distribution. Email the show at themidnightmailbag@gmail.com!

Exosomes are becoming one of the most talked-about tools in regenerative medicine, but not all exosomes are created equal. In this episode of New Frontiers, Dr. Kara Fitzgerald talks with Alisa Lask, CEO of Plated Skin, about the science behind platelet-derived exosomes and why their signaling pathways matter for repair, renewal, and changes in skin appearance. We explore how discoveries in cardiology led to this technology, what early clinical studies are showing, and why source and preparation are critical when evaluating any exosome-based approach. A clear, grounded look at a fast-moving field for clinicians who want to understand what's real, what's emerging, and what deserves attention next. Full show notes + references: https://www.drkarafitzgerald.com/fxmed-podcast/ GUEST DETAILS Alisa Lask is the CEO of Rion Aesthetics, where she is driving innovation in regenerative aesthetics with platelet-derived exosomes and leading research in areas like hair restoration and skin appearance. She also oversees (plated)™ Skin Science, a medical-grade exosome skincare line distributed through aesthetic providers. Alisa previously held senior roles at Galderma, Allergan, Zimmer-Biomet, and Eli Lilly, and she serves on the Board of Directors for CollPlant. She holds an MBA from the University of Michigan and is also a nationally competitive show-jumping equestrian involved in dog rescue initiatives. THANKS TO OUR SPONSOR (plated)™ Skin Science: http://platedskinscience.com/ Plated Skin Science translates the discovery of Dr. Atta Behfar, M.D., Ph.D., Director of Mayo Clinic's Van Cleve Cardiac Regenerative Medicine Program into the first shelf-stable skincare line using regenerative, platelet-derived exosomes. These aren't generic exosomes; they're a specific class shown in peer-reviewed trials to regenerate skin's appearance by improving the look of wrinkles, pigmentation, luminosity, and overall skin quality. It's an elegant approach to visible signs of skin aging, recognized by Time as a Best Invention of 2024 and now used in more than 2,000 medical practices. Learn more at http://platedskinscience.com/ CONNECT with DrKF Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You Practitioner Training Program: www.drkarafitzgerald.com/trainingyyi/ Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

This is the fifth lesson in Dr. James Cassidy's Reformed Academy course, The Doctrine of the Church. This lesson covers the following topics: 00:00 Church Power is Suasive, not Coercive 15:21 Church Power is Service, not Domination 19:01 Church Power is Spiritual, not Carnal 23:00 Church Power is Ministerial, not Magisterial 26:17 Church Power is Declarative, not Legislative 28:18 Church Power is Derived, not Original 30:40 The Spirituality of the Church Register for this free on-demand course on our website to track your progress and assess your understanding through quizzes for each lesson. You will also receive free access to dozens of additional video courses in covenant theology, apologetics, biblical studies, church history, and more: https://reformedacademy.org/course/do... Your donations help us to provide free Reformed resources for students like you worldwide: https://reformedforum.org/donate/ #church #reformed #presbyterian #ecclesiology #reformedtheology

This is the fifth lesson in Dr. James Cassidy's Reformed Academy course, The Doctrine of the Church. This lesson covers the following topics: 00:00 Church Power is Suasive, not Coercive 15:21 Church Power is Service, not Domination 19:01 Church Power is Spiritual, not Carnal 23:00 Church Power is Ministerial, not Magisterial 26:17 Church Power is Declarative, not Legislative 28:18 Church Power is Derived, not Original 30:40 The Spirituality of the Church Register for this free on-demand course on our website to track your progress and assess your understanding through quizzes for each lesson. You will also receive free access to dozens of additional video courses in covenant theology, apologetics, biblical studies, church history, and more: https://reformedacademy.org/course/doctrine-of-the-church Your donations help us to provide free Reformed resources for students like you worldwide: https://reformedforum.org/donate/

Jo and Rob know you need some space, but the latest episode of Apple TV's ‘Pluribus' deserves a recap, so here it is! (0:00) Intro (3:17) Thoughts on episode 6 (9:40) The tricky balance of Koumba (13:30) Listener emails (20:04) Let's talk about consent (32:46) Human-Derived Protein (40:26) Carol's isolation (46:46) Giliigan-verse shots Email us! prestigetv@spotify.com or lickingthedonut@gmail.com Subscribe to the Ringer TV YouTube channel here for full episodes of The Prestige TV Podcast and so much more! Hosts: Joanna Robinson and Rob Mahoney Producer: Donnie Beacham Jr. Additional Production Support: Justin Sayles Learn more about your ad choices. Visit podcastchoices.com/adchoices

War Gaming a Russian Invasion of Estonia: NATO's Article 5 Crisis — General Blaine Holt — General Holtdiscusses a scenario derived from Carlo Masala's book If Russia Wins, depicting Russian military seizure of the Estonian town of Narva in 2028 using ambiguous hybrid tactics. Holt emphasizes that this scenario exposes NATO'sfundamental bureaucratic paralysis, organizational hesitation to invoke Article 5 collective defense provisions, and the catastrophic risk of nuclear miscalculation when confronting strategically ambiguous Russian aggression that blurs the distinction between conventional military action and state-sponsored covert operations. 1927 POLAND