Podcasts about intrahepatic cholestasis

In this episode, Riley Kirk shares her personal journey through pregnancy, focusing on her experiences with cannabis use, tapering down her consumption, and the emotional and physical changes she faced. She discusses the importance of mental health during this time, the role of her supportive partner, and the diagnosis of intrahepatic cholestasis of pregnancy (ICP). The conversation also touches on the gender reveal process and the complexities of navigating a high-risk pregnancy. In this conversation, Riley Kirk shares her personal journey with Intrahepatic Cholestasis of Pregnancy (ICP), a rare liver condition that can occur during pregnancy. She discusses the emotional and physical challenges she faced, the medical treatments available, and the lifestyle changes she made to manage her symptoms. Riley emphasizes the importance of mental health support and community during this difficult time, and reflects on her experiences as a pregnant woman in the cannabis community. She also expresses gratitude for the support she received from friends and family, and looks forward to continuing the conversation about women's health and pregnancy in future episodes. THE MAIN TAKEAWAY OF THIS EPISODE IS TO BE YOUR OWN ADVOCATE DURING PREGNANCY. PHYSICIANS KNOW A LOT BUT YOU ARE THE EXPERT ON YOUR OWN BODY. (THERE'S ALSO A SECRET SEED GIVEAWAY IF YOU CLICK THE PATREON LINK) Chapters 00:00 Introduction to Pregnancy Journey and Cannabis Use 03:11 Discovering Pregnancy and Initial Reactions 05:55 Tapering Down Cannabis Consumption 08:48 Methods of Consumption and Personal Preferences 12:01 Managing Migraines and Mental Health During Pregnancy 15:11 The Role of Supportive Partners 18:00 Gender Reveal and Early Testing 20:51 High-Risk Pregnancy and ICP Diagnosis 27:14 Understanding Intrahepatic Cholestasis of Pregnancy (ICP) 30:00 The Emotional Toll of High-Risk Pregnancy 33:07 Treatment Options and Medical Anomalies 35:53 Lifestyle Changes and Natural Remedies 40:09 Mental Health and Support During Pregnancy 44:01 Reflections on Pregnancy and Community Support 49:00 Looking Ahead: Future Topics and Conversations Preorder my book Reefer Wellness! ⁠⁠⁠https://www.amazon.com/Reefer-Wellness-Understanding-Cannabis-Medicine/dp/0593847156⁠⁠⁠ ✨ Want Exclusive Content? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one.⁠⁠⁠ www.Patreon.com/Cannabichem⁠⁠⁠

This educational program, hosted by Patrick McKiernan, MD, Pediatric Hepatologist at Birmingham Children's Hospital NHS Foundation Trust and Nadia Ovchinsky, MD, Professor of Medicine at NYU Grossman School of Medicine discuss the recently published guidance on best practices to diagnose, treat, and monitor patients with PFIC. It also explains why the new guidance recommends the early use of IBAT inhibitors in patients suspected of having progressive familial intrahepatic cholestasis (PFIC).PFIC encompasses a spectrum of autosomal recessive disorders characterized by impaired bile flow (cholestasis) due to defects in biliary epithelial transporters. These rare genetic conditions typically manifest in infancy or early childhood, leading to severe liver dysfunction and potentially life-threatening complications if left untreated. Common early symptoms observed in children with PFIC are jaundice, pruritus, elevated serum bile acid (SBA) values, malabsorption, and failure to thrive. PFIC can be a debilitating condition that significantly impacts the quality of life and can result in end-stage liver disease. As such, early detection and effective intervention are imperative for the prevention of disease progression. Unfortunately, there are no relevant guidelines based on newly published research to help healthcare providers manage patients with PFIC. However, a recent opinion paper by leading experts in the management of PFIC provides evidence-based guidance on this subject and was recently published in JHEP Reports. This educational program is made possible by an unrestricted grant from Ipsen.

If you're looking at the title of this episode thinking, “I've never heard of cholestasis”… you're not alone! That being said, it's important to know about as it can occur in 1-2 in every 1,000 pregnancies. So let's talk about cholestasis in pregnancy- the symptoms, the treatment, how it is diagnosed, and how one can deal with this in pregnancy.  To have this conversation with me today on Yoga | Birth | Babies, I have Donna Benavides. Donna is a mother who experienced Cholestasis of Pregnancy and is now blessed with two healthy teens, Branden & Evan, and her angel baby Jorden. She's dedicated her time and advocacy to Intrahepatic Cholestasis of Pregnancy (ICP) and is the Founder of ICP Care 501(c)(3) nonprofit. She is also a registered prenatal yoga teacher! Donna has had ICP in all 3 of her pregnancies, and she graciously shares the knowledge and experience she's gained on the diagnosis through our honest conversation. If you have ICP or it comes up later on in your pregnancy, we want you to know how to advocate for yourself in order to find the support you need in guiding you through a healthy pregnancy. **CW: In this episode, there is mention of a stillbirth. This experience is shared about within the first 16 minutes. Please feel free to skip ahead, because there is so much good advice offered throughout the rest of our conversation as well.** Get the most out of each episode by checking out the show notes with links, resources and other related podcasts at: prenatalyogacenter.com Don't forget to grab your FREE guide, 5 Simple Solutions to the Most Common Pregnancy Pains HERE  If you love what you've been listening to, please leave a rating and review! Yoga| Birth|Babies (Apple) or on Spotify!  To connect with Deb and the PYC Community:  Instagram & Facebook: @prenatalyogacenter Youtube: Prenatal Yoga Center Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode, we discuss the presentation, typical timing of onset, investigations and treatment for individuals with intrahepatic cholestasis of pregnancy. We also discuss the potential complications of ICP. Written by: Dr. Kristina Wade (Internal medicine resident)Reviewed by:  Dr Giada Sebastiani (Hepatologist) and Dr Camille Simard (GIM/Ob Med)Support the Show.

Intrahepatic cholestasis in pregnancy or ICP is a condition that affects about 1% of pregnant people. It is a complication caused by the liver and acid bile build up in the body and can cause increased risk of other pregnancy conditions such as gestational diabetes. It commonly causes extreme itching which can be distressing and affect every aspect of life during pregnancy. I chat to Katie, a mother and midwife, about ICP. You can find support for ICP at charity https://www.icpsupport.org/ You can find Katie @midwifepatch on instagram, Facebook and tiktok! Disclaimer: The information and provided on this podcast does not, and is not intended to, constitute medical or legal advice; instead, all information available on this site are for general informational purposes only. We reserve the right to supplement, change or delete any information at any time. The information and materials on the podcast is provided "as is"; no representations are made that the content is error-free. Whilst we have tried to ensure the accuracy and completeness of the information we do not warrant or guarantee the accurateness. All liability with respect to actions taken or not taken based on the content of the podcast are hereby expressly disclaimed. Your use of content contained in or linked to this podcast is entirely at your own risk. The Better Birth podcast accepts no liability for any loss or damage howsoever arising out of the use or reliance on the content.

Join us as we celebrate the arrival of Stu's first grandchild, and finally cover a topic that has been highly requested: cholestasis. This is a lesser-known health issue that affects a significant number of pregnant women and usually results in interventions once it is discovered. You'll walk away from this episode with a deeper understanding of cholestasis - from its potential treatments, its impact on the liver, and whether or not it is as scary as it is sometimes portrayed.We dissect the risks and benefits of various treatments for cholestasis, alongside a poignant story from a listener who was diagnosed with this condition. We don't shy away from examining the harsh realities, but also shed light on the real facts of what different bile levels mean and their corresponding risks. We further delve into the medical model of treating cholestasis, highlighting the need for an individualized approach that takes into account the woman's unique experience and not just the medical perspective.Not only do we discuss cholestasis, but we also tackle topics like the potential risks of placental pathology and the controversy surrounding forceps usage in childbirth. We pull back the curtain on the medical world, questioning the incentives behind the non-disclosure of placental pathology by hospitals, and revisiting the debate on the induction of labor. This episode is packed with valuable insights, personal stories, and expert advice - an invaluable resource for anyone seeking a comprehensive understanding of cholestasis and its management during pregnancy. Tune in and let's grow together!The Biology of Aging and FertilitySensitivity of Hands and FeetReevaluating Induction Practices in ObstetricsCholestasis in Pregnancy and Risk FactorsPreeclampsia Risk in ICP PatientsAntepartum Testing in Intrahepatic CholestasisLikelihood of ICP RecurrenceObstetricians' Approach to Risk and IndividualityRespiratory Distress Syndrome in Cholestatic PregnanciesEpisode resources:Statistics: Risk of Stillbirth with Intrahepatic Cholestasis of Pregnancy: What do Bile Acid Concentrations Tell Us?This show is supported by:LMNT | Go to com/birthinginstincts to get a free sample pack with every orderNeeded | Use code BIRTHINGINSTINCTS for 20% off your first month or first 3 months of a one-month subscription at com.BIRTHFIT | Go to com and use the code INSTINCTS1 for a discount on the Basics Prenatal program, or INSTINCTS2 for a discount on the Basics Postpartum program.Connect with Dr. Stu & Blyss:Instagram: @birthinginstincts / @birthingblyssWebsite: com / birthingblyss.comEmail: birthinginstinctspodcast@gmail.comCall-in line: 805-399-0439

Donna Benavides is a mother who experienced Cholestasis of Pregnancy and is blessed with two healthy children Branden & Evan and angel baby Jorden. Her time is dedicated to her family, work and passion to raise awareness of Intrahepatic Cholestasis of Pregnancy (ICP). Her journey with ICP began with her first pregnancy in 2003 with her son Jorden that tragically passed away in utero at 37 weeks & 5 days due to the high-risk pregnancy Cholestasis. In 2008, she began her work with the itchy mom's website and in 2012 became the Founder of ICP Care 501(c)(3) nonprofit. She has a Bachelor's of Science degree and has practiced Yoga for 12 years completing her RYT® 200 Yoga Teacher training in 2018.  She has enjoyed teaching to pregnant mothers since 2019 as a certified Prenatal Yoga Teacher RPYT®.  Website: https://icpcare.org/   Facebook- https://www.facebook.com/icpcare Instagram- https://www.instagram.com/icpcare Twitter- https://twitter.com/icpcare YouTube- https://www.youtube.com/user/icpcare   Support group page https://icpcare.org/icp-community/support-groups/     For more information about Michelle, visit www.michelleoravitz.com The Wholesome Fertility facebook group is where you can find free resources and support: https://www.facebook.com/groups/2149554308396504/ Instagram: @thewholesomelotusfertility Facebook: https://www.facebook.com/thewholesomelotus/

Learn all about this rare complication of pregnancy, how to know if you're at risk, how to know if you have it, and what the midwifery model of care can offer for management. https://hearthandhomemidwifery.com

Intrahepatic Cholestasis of Pregnancy (ICP).Amel and Dr Wonderly discuss the signs, symptoms, and management of ICP. A reminder for alcohol use disorder screening.Introduction: Screening for alcohol use disorder. Written by Hector Arreaza, MD. Reviewed by Jacqueline Uy, MD. Today is December 3, 2021.Substance misuse occurs in about 20% of patients seen in primary care settings. For example, alcohol-related disorders are present in up to 26% of general clinic patients, “a prevalence rate similar to those for such other chronic diseases as hypertension and diabetes”[1]. The USPSTF recommends screening for unhealthy alcohol use in adults 18 years or older, including pregnant women, and provide those engaged in risky drinking with brief behavioral counseling to reduce alcohol use (this is a Grade B recommendation). This brief introduction is to encourage everyone to screen adults for alcohol use disorder. Let's start with the basics.  It is important to know the size of a standard drink so you can counsel your patients appropriately. According to the CDC, a standard drink is equal to 14 grams (0.6 ounces) of pure alcohol. Generally, this amount of pure alcohol is found in:12 ounces of beer (5% alcohol content).8 ounces of malt liquor (7% alcohol content).5 ounces of wine (12% alcohol content).1.5 ounces or a “shot” of 80-proof (40% alcohol content) distilled spirits or liquor (such as gin, rum, vodka, whiskey).Moderate alcohol drinking means 2 drinks or less in a day for men and 1 drink or less in a day for women. Binge drinking means drinking enough to bring your blood alcohol concentration (BAC) level to 0.08% or more. This may be different in each patient, as humans metabolize alcohol differently, but usually it corresponds to 5 or more drinks on a single occasion for men or 4 or more drinks on a single occasion for women, generally within about 2 hours[2]. A good approach to screen for alcohol use disorder is by asking: “Do you sometimes drink alcoholic beverages?”, and then the single screening question, “How many times in the past year have you had 5 or more drinks (men) OR 4 or more drinks (women) in a day?”[3]  The screening is considered positive if the patient answers one or more times a year. If positive, then you may continue your assessment with another tool such as AUDIT. This can be a topic for a whole episode.  For now, we just want to remind you to screen your patients for alcohol use because the prevalence is very high and we as primary care physicians can make a big difference in the prevention and treatment of alcohol misuse in our communities.  This is Rio Bravo qWeek, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California. Our program is affiliated with UCLA, and it's sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. Intrahepatic Cholestasis of Pregnancy (ICP). Written by Amel Tabet, MS3, American university of the Caribbean. Discussion with Sally Wonderly, MD; and Hector Arreaza, MD.What is Intrahepatic Cholestasis of Pregnancy and why does it matter?As its name implies, Intrahepatic Cholestasis of Pregnancy (ICP) is a multifactorial liver dysfunction in some pregnant women that occurs during their either second or third trimester of pregnancy and resolves spontaneously after parturition. It is defined by the presence of pruritus -- previously called pruritus gravidarum or recurrent jaundice of pregnancy-- and abnormally elevated serum bile acid levels and mildly increased hepatic aminotransferase levels, in the absence of diseases that may yield similar laboratory findings and symptoms. Key symptoms are pruritus, high bile acid and high transaminases. How common is ICP?In the US incidence ranges from 0.32 percent to 5.6 percent, depending on the area. The Los Angeles area has a high incidence compared to other areas in the US. The highest rates in Europe are in Scandinavia. It is very frequent in Chile (South America). The indigenous people known as Araucanos have the highest incidence worldwide at 27.6 percent.PathogenesisThe pathogenesis of ICP remains unclear. It is mainly attributed to changes in various sex steroid levels but more recent research points towards an etiology that relates to various mutations in the many genes involved in the control of the hepatocellular transport systems such as the ABCB4 gene, which encodes multidrug resistance protein 3 (MDR3) linked to progressive familial intrahepatic cholestasis, errors of the ABCB11 gene that encodes for the bile salt export pump, and more recently on FXR/NR1H4 and PXR/NR1I2 genes that encode for proteins that critically regulate bile acid synthesis and transport, and the transcription of ABCB11 in humans and the role of epigenetics influence by means of methylation of these genes. Dangers for mother: Beside the discomfort of pruritus, ICP is transient and of little maternal risk generally. The mother may be uncomfortable but it's not fatal. Danger to fetus: The elevated bile acids enter the fetal circulation because it crosses the placenta. Bile acids cause major fetal and neonatal complications, such as abnormal intrapartum fetal heart rate and meconium-stained amniotic fluid that can lead to fetal distress and prematurity or intrauterine demise and to neonatal respiratory distress syndrome associated with bile acids entering the lungs. Who is at risk for ICP?Multifetal pregnancies.Genetics: There is also a significant genetic influence that leads to variability of incidence by population. In North America, cholestasis is infrequent with an overall incidence approximating 1 case in 500 to 1000 pregnancies. Whereas its rate is high in indigenous women from Chile and Bolivia and nears 5.6 % among Hispanic women in Los Angeles. In other countries, for example Sweden, China, and Israel, the incidence varies from 0.25 to 1.5 %.Diet and environment can also have an influence. Research has shown an association of ICP with environmental and dietary factors such as seasonal changes of mineral dietary components and with gut-derived endotoxins subsequent to increased gastrointestinal permeability. This complex nature-nurture interaction suggests that ICP is strongly modulated by epigenetic mechanisms.Liver disease: Women with preexisting liver disease are at risk. Other risks include in vitro fertilization, cholelithiasis, advanced maternal age, and Hepatitis C and fatty liver disease.  History of ICP is an important risk, because it also recurs during subsequent pregnancies in 60 to 70 % of patients. Signs and symptoms:The main clinical presentation is an often-generalized pruritus in late second or third trimester, that usually starts and predominates on the palms and soles and is worse at night. It could range from mild to intolerable pruritus that may precede laboratory findings by several weeks and evidenced by possible presence of scratch marks and excoriations on physical examination. Jaundice arises in 14 to 25 % of patients and it typically develops 1 to 4 weeks after the onset of itching. Other accompanying symptoms may also occur such as nausea, RUQ pain, steatorrhea, poor appetite and sleep deprivation. Other signs include dark urine, pale stools. Diagnosis:To establish a diagnosis, careful history taking, physical examination, and laboratory evaluation are performed. Thus, in the absence of any other liver disease, ICP is diagnosed by the presence of pruritus that is associated with elevated total serum bile acid levels, elevated aminotransferases (seldom exceed 250 U/L), hyperbilirubinemia (4 to 5 mg/dL) and elevated alkaline phosphatase. In severe cases that account for 20%, cholestasis manifests as bile acids levels > 40 micromol/L.Differential diagnosis include: Preeclamptic liver disease, which is ruled out if blood pressure elevation or proteinuria are absent and cholelithiasis and biliary obstruction are excluded by sonography. Moreover, because of mild transaminitis in case of ICP, acute viral hepatitis is an improbable diagnosis. Liver biopsy is generally not needed. Even though not necessary for diagnosis, liver biopsy for research purposes, showed occurrence of changes with presence of cholestasis with bile plugs in the hepatocytes and canaliculi of the centrilobular regions, without inflammation or necrosis. These changes were found to fade after delivery with recurrence in successive pregnancies or with estrogen-containing contraceptives.Management:Management focuses mainly on reducing maternal discomfort due to pruritus and prevention of more serious fetal outcomes and reduce the risks of prenatal morbidity and mortality. For patients that have persistent clinical findings consistent with ICP without any biochemical evidence of ICP, we only treat with antihistamines and topical emollients such as calamine lotion and we perform a weekly evaluation of maternal total serum bile acid (TSBA) level.  In symptomatic patients with positive biochemical evidence of ICP we treat with ursodeoxycholic acid (UDCA) 300 mg BID or TID until delivery. UDCA was found in clinical trials to relieve pruritus, lower bile acid and serum enzyme levels, and to reduce preterm birth, fetal distress, respiratory distress syndrome, and neonatal intensive care unit admission. Along with treatment, we continue the weekly evaluation of the TSBA level with a warranted earlier delivery if TSBA ≥100 micromol/L and the related high risk of stillbirth.  Thus, delivery management is mainly based on the highest TSBA level at any time during pregnancy. If TSBA level is

Intrahepatic cholestasis of pregnancy (ICP or IHCP) is characterized by itching and an elevation in blood bile acids, that usually develops in the late second and/or third trimester and can be a high risk issue in pregnancy.  Check us out on our website or social media! www.truebirthpodcast.com Maternal Resources Social Facebook: https://www.facebook.com/maternalresourceshackensack |nstagram: @maternalresources Subscribe to the podcast on Apple Podcasts, Spotify, Google Podcasts, & Stitcher and leave a review!  

Our understanding of Intrahepatic Cholestasis of Pregnancy has changed just over the last 5 years. What is the best laboratory test to help diagnose this condition? At what level of total serum bile acids is the risk of fetal death greatest? What does the SMFM say about induction of labor for these patients? In this episode, we will highlight and summarize the latest clinical brief on ICP from the SMFM (2021). This is SMFM consult series # 53.

Caroline Ovadia (King's College London) discusses an individual participant data meta-analysis on the treatment of intrahepatic cholestasis of pregnancy with ursodeoxycholic acid.

This week we welcome Dani. Dani is a first time mum to baby Wyatt and discusses very openly about her diagnosis of Intrahepatic cholestasis of pregnancy (ICP) at week 25 and shares her story for other mums to be aware of the symptoms, what to expect if you have ICP and how it effected her overall experience. You can read Dani's guest blog about her experiences with ICP over at www.theswaneffectmum.com If you have a story you'd like to share and would like to be a guest on the show then please email Lynne at theswaneffectmumblog@gmailcom

We cover an important topic today on IHCP.How do you diagnose cholestasis? When should you deliver?  Come find out on this episode of CREOGs Over Coffee.  Twitter: @creogsovercoff1  Instagram: @creogsovercoffee Facebook: www.facebook.com/creogsovercoffee Website: www.creogsovercoffee.com Patreon: www.patreon.com/creogsovercoffee You can find the OBG Project at: www.obgproject.com

Donna Benavides, Founder and Chair of the non-profit ICPcare.org joins host Chris Stallman, a certified genetic counselor, and special guest expert Alfred Romeo, RN, PhD to talk about the less known condition of Intrahepatic Cholestasis of Pregnancy (ICP). Chris and Alfred answer commonly asked questions Donna receives through her supportive community of pregnancy women affected by ICP. This episode contains evidence-based information that's current as of the day published and may change as data emerges. To get the very latest information about this topic in pregnancy/breastfeeding, please contact a MotherToBaby specialist at 866-626-6847, via text message at 855-999-3525 or through https://mothertobaby.org. 

When Bryn got pregnant with her third child, she planned for another unmedicated birth in a birth center. The plan changed when she was diagnosed with Intrahepatic Cholestasis of Pregnancy(ICP) at 33 weeks and risked out of the birth center.

Madeline shares about giving birth during COVID-19 and discusses ICP.

In episode 57 of Kiwi Birth Tales I speak with Katie Hawkey about the birth of her daughter Coco. Katie takes us through their journey getting pregnant, her extreme Hyperemesis Gravidarum which was paired with antenatal anxiety (and mainly linked to this). Katie was living in London and takes us through the healthcare model there, as well as antenatal mental health appointments to assist with anxiety. Katie returned to NZ at the end of her pregnancy and discusses this experience, as well as having Intrahepatic Cholestasis of Pregnancy and needing to be induced as a result. Katie was induced twice as the first time didn't work, she takes us through the induction process and her labour / birth where she needed an episiotomy and later on had surgery to remove scar tissue. Katie then discusses their difficult start to breastfeeding, persisting with it and now still feeding 1 year on. Katie is a Midwife here in NZ and it's great to hear about this from her perspective as both a Midwife and a first time Mum. Thanks so much for joining me on the podcast Katie - if you want to head over and follow her page you can do so @katieinthekitchenThis episode is proudly sponsored by New Edition - New Edition by Green Group Collective, create affordable essentials that are designed and made in New Zealand with non-toxic materials, natural ingredients and less packaging. Simpler for you, safer for baby, and kinder to our planet. They like to reduce waste, keep things simple and ensure everything they do is making caring for your babe as safe and stress free as possible. Theteam are proud to launch the very first NZ designed and manufactured manual breast pump as well as a sanitisation range, which is also made in our home land.

Intrahepatic Cholestasis of pregnancy (ICP) is a condition that can occur during pregnancy that typically causes very uncomfortable itching for the expectant mother but can be more serious for the baby.  Our guests  Dr. Emiliano Chavira and Midwife Davi Khalsa discuss what cholestasis is,, how often it occurs, signs and symptoms, testing and treatment options. Learn more about your ad choices. Visit megaphone.fm/adchoices

Nicole Phelps shares her experience being pregnant while her partner, Michael Phelps, was training for the Olympics. She hired a doula and prepared to possibly give birth without Michael there. A few weeks before her due date, Nicole started experiencing extreme itchiness, especially on the palms of her hands, and was tested for Intrahepatic Cholestasis of Pregnancy (ICP). However, she went into labor before the results came back. Michael made it just in time, and her son, Boomer, was born healthy. The test result came back positive and she knew she'd have to be on the lookout for another ICP diagnosis with future pregnancies. On this episode, she also shares her second pregnancy and birth story and how her doctor monitored her for ICP leading up to her son Beckett's birth. Nicole wanted to share her story to raise awareness about ICP so other women can be on the lookout for the symptoms.

In this episode of Stillbirth Matters, Chris Duffy visits with Yasuko Yamamura, MD about Intrahepatic Cholestasis of Pregnancy (IHCP). Dr. Yamamura is Assistant Professor in the Department of Obstetrics, Gynecology and Women’s Health at the University of Minnesota . She received her medical degree from the Ponce School of Medicine in 2001. She went on […]

Intrahepatic Cholestasis of Pregnancy by The Society for Academic Specialists in General Obstetrics and Gynecology

Hi, Momma! Today’s episode is so special as the beautiful Kelly shares her story + experience Intrahepatic Cholestasis of Pregnancy (ICP). Her heart for mommas with this condition shines as she shares in honor of her son James. We hope you feel informed and equipped on all things ICP after listening! XOXO

Dr. Sara Kim discusses the etiology, diagnosis, and management of intrahepatic cholestasis of pregnancy. Website Slack Patreon feedback@obgyn.fm Fast, B., & Roulston, T. (1963). Idiopathic jaundice of pregnancy. Am J Obstetrics and Gynecology, 314-320. Geenes, V., & Williamson, C. (2009). Intrahepatic cholestasis of pregnancy. World Journal of Gastroenterology, 2049-2066. Gynecologists, R. C. (2011). Obstetric Cholestasis. Jurate, K., Rimantas, Z., Jolanta, S., Vladas, G., & Limas, K. (2017). Sensitivity and specificity of biochemical tests for diagnosis of intrahepatic cholestasis of pregnancy. Annals of Hepatology, 569-573. Kenyon, A., Piercy, C. N., Girling, J., Williamson, C., RM, T., & Shennan, A. (2002). Obstetric cholestasis, outcome with active management: a series of 70 cases. BJOG: an International Journal of Obstetrics and Gynecology, 282-288 Lammert, F., Marschall, H.-U., Glantz, A., & Matern, S. (2000). Intrahepatic cholestasis of pregnancy: molecular pathogenesis, diagnosis and management. Journal of Hepatology, 1012-1021. Lindor, K., & Lee, R. (2018). Intrahepatic cholestasis of pregnancy. Retrieved from UptoDate: https://www.uptodate.com/contents/intrahepatic-cholestasis-of-pregnancy?search=cholestasis%20of%20pregnancy&source=search_result&selectedTitle=1~59&usage_type=default&display_rank=1 Pusl, T., & Beuers, U. (2007). Intrahepatic cholestasis of pregnancy. Orphanet Journal of Rare Diseases.   

The Brave Files returns this week with an inspiring story of friendship, surrogacy, and jumping into a familiar unknown. Heather sits down with longtime friend, Karen Kitto, this week to talk about her brave and selfless decision to be a surrogate for friends who were unable to carry their own children.One day about 10 years ago Karen had a random thought that simply wouldn't go away. She thought about being a surrogate for her friends, who were struggling to have their own children. Karen describes the decision as her “buying them admission to the amusement park.” She could carry the baby so that they could have the lifetime adventure of parenthood. After one failed attempt to inseminate, Karen was surprised to learn she was carrying two babies! It was a wonderful shock to her and to the mother of the babies.As with all stories, there were some struggles. Learning to juggle caring for Juggling taking care of her own two children and carrying two babies was a difficult job! She also developed Intrahepatic Cholestasis during the pregnancy which resulted in an early c-section.All in all, Karen says she would make this sacrifice again if presented the opportunity.Details show notes here.

In this session, we will cover intrahepatic cholestasis of pregnancy. We will cover background, work-up, and management options for this condition.

Join Aglaée as she interviews Amelia Barnes to first talk about the benefits of yoga for moms and the important role yoga has played in her life, including during both of her pregnancies and postpartum periods. In the second part of the interview, you will learn about Amelia's incredibly inspiring story with her first baby, Landon, unexpectedly passing away only 4 days after he was born and how he saved his sister's life. Enjoy the listen! :) Amelia Barnes's bio: Amelia Kathryn Barnes is a yoga teacher, retreat facilitator and small business owner. She teaches at Moksha Yoga Winnipeg and is a guide at the yoga and wellness website oneOeight.com. She is also the creator of PranaVidaStyle, a unique line of inspired and Canadian-made yoga apparel. Amelia lives in Winnipeg, Canada with her husband Justin, daughter Lily and their big white mutt Cody. Amelia Barnes TIMESTAMPS: [0:00] Intro [3:27] Welcome Amelia! - Let's talk about yoga for moms! How she got started with yoga Pros and cons of practicing at home vs at a studio [8:27] Yoga beyond the physical practice [11:25] Yoga for better immunity [12:40] Yoga as a tool to reconnect to our bodies [14:10] Anxiety about going to a yoga studio for the 1st time!!! [17:35] Yoga and body image / self-acceptance [22:10] Amelia's 3 favorite poses for moms           ********** [27:05] Landon's story [33:10] Tips for moms dealing with baby loss [37:30] Amelia's thoughts on "letting go" vs "setting free"           ********** [39:44] Lily's story and why you need to know about ICP (ICP stands for Intrahepatic Cholestasis of Pregnancy) [50:15] Where to find more about Amelia [51:00] Outro Click here to listen or find the podcast on iTunes or Stitcher! Shownotes: Online yoga platform: oneOeight.comAmelia's yoga apparel: PranaVida Style Amelia's book: Landon’s Legacy: The Power of a Short Life Other resources: ICP (intrahepatic cholestasis of pregnancy) icpcare.org  Yoga Body Coalition on Instagram Steph's Healthy Mama, Happy Baby Virtual Pregnancy Handbook Aglaée's Free 7-day Bloat-Free Forever Online Course   Disclaimer Please remember that the views on this podcast and website are not meant to be substituted for medical advice, shouldn’t be used to diagnose, treat or cure any conditions, and are intended for general information purposes only.

Intrahepatic cholestasis of pregnancy (ICP) is a cholestatic disorder characterized by (i) pruritus with onset in the second or third trimester of pregnancy, (ii) elevated serum aminotransferases and bile acid levels, and (iii) spontaneous relief of signs and symptoms within two to three weeks after delivery. ICP is observed in 0.4-1% of pregnancies in most areas of Central and Western Europe and North America, while in Chile and Bolivia as well as Scandinavia and the Baltic states roughly 5-15% and 1-2%, respectively, of pregnancies are associated with ICP. Genetic and hormonal factors, but also environmental factors may contribute to the pathogenesis of ICP. Intrahepatic cholestasis of pregnancy increases the risk of preterm delivery (19-60%), meconium staining of amniotic fluid (27%), fetal bradycardia (14%), fetal distress (22-41%), and fetal loss (0.4-4.1%), particularly when associated with fasting serum bile acid levels > 40 mu mol/L. The hydrophilic bile acid ursodeoxycholic acid (10-20 mg/kg/d) is today regarded as the first line treatment for intrahepatic cholestasis of pregnancy. Delivery has been recommended in the 38(th) week when lung maturity has been established.