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In this episode of the Prolonged Field Care Podcast, Dennis sits down with J.R. Pickett — unpack the controversial and high-stakes topic of what used to be called excited delirium.They dig into the history of the syndrome (Bell's mania, acute exhaustive mania, agitated delirium), why major organizations including ACEP, ACMT, and the National Association of Medical Examiners have rejected the term, and the preferred modern language: hyperactive delirium with severe agitation. The conversation covers real-world presentation, the physiologic cascade that can lead to sudden cardiovascular collapse, the critical differences between a contained hospital environment and the uncontrolled street or austere setting, and the hard lessons from the Elijah McClain case.J.R. walks through practical decision-making for EMS and tactical medics: when de-escalation is possible, when sedation becomes necessary, why intramuscular ketamine remains the most forgiving and rapid option for the violently agitated patient, how to prepare for the predictable risks (brief apnea, loss of airway protection, metabolic derangement), and why continuous medical eyes-on monitoring after sedation is non-negotiable. They also address the dangerous intersection of law enforcement and medical care, the myth of “if they can talk they can breathe,” and the growing criminalization of medical decision-making that threatens providers' willingness to engage.Key TakeawaysThe condition is a true medical emergency with historically high mortality, even without restraint or intervention.Engagement ability is a practical field litmus test: if the patient cannot be redirected or answer basic questions, rapid intervention is usually required.Ketamine's wide therapeutic index and rapid IM onset make it the preferred agent for violent agitation when IV access is impossible — but it is not risk-free.Sedation is a procedure. Have airway equipment, monitors, and a clear team plan ready before the drug is given. Continuous medical provider eyes-on is mandatory in the early phase.“If you can talk, you can breathe” is dangerous teaching. Treat complaints of inability to breathe seriously.Noble intent + thorough preparation is the best defense against both bad outcomes and the growing criminalization of medical care.Chapters02:45 – What is (or was) excited delirium? History, physiology, and why the term is being abandoned09:30 – Real-world presentation vs. “just being a jerk” and the challenge of the uncontrolled environment15:20 – Elijah McClain case and the broader controversy around restraint, force, and medical justification21:00 – Causes of severe agitation and the difficulty of sorting them in the field26:45 – Clinical clues and the “can I engage?” litmus test32:10 – The physiology of sudden collapse: acidosis, rhabdomyolysis, and the danger of sudden quiet37:40 – “I can't breathe” and why that teaching is hazardous45:50 – Ketamine deep dive: dosing, therapeutic index, risks, and why it is still the safest rapid option55:20 – Comparison with benzodiazepines and antipsychotics; timing matters01:01:00 – Treating sedation like a procedure: airway readiness, monitoring, team roles, and continuous eyes-on01:10:30 – Police vs. medical roles, the myth of walking away, and the duty to act01:18:00 – Criminalization of medical care and final thoughts on honorable intentFor more content, go to www.prolongedfieldcare.orgConsider supporting us: patreon.com/ProlongedFieldCareCollective or www.lobocoffeeco.com/product-page/prolonged-field-care
In this episode Dr. Gillian Beauchamp sits down with Donna Papsun to discuss the nuance of forensic laboratory testing of Kratom products, especially with the development of synthetic Kratom alkaloids.
In this episode Dr. Gillian Beauchamp sits down with Dr. Patil Armenian to discuss how US federal law may hinder harm reduction efforts at mass gatherings/festivals and how toxicologists can get involved.
In this episode Dr. Gillian Beauchamp sits down with Dr. Cait Bonney to discuss MDMA.
ACMT Highlights Episode 70 - Festival Drugs In this episode Dr. Gillian Beauchamp sits down with Dr. Benjamin Hatten to discuss drug use during festivals including self report of substances used versus what is found on surveillance testing.
In this episode Dr. Gillian Beauchamp sits down with Dr. Tim Erickson to discuss CBRNE and mass casualty training in Ukraine.
In this episode Dr. Gillian Beauchamp sits down with Dr. Robert "Cole" Pueringer to discuss 3 key features of fentanyl which lead to high opioid tolerance. This high opioid tolerance can lead to more severe withdrawal syndromes and difficulty with initiating buprenorphine or methadone. Rapid inpatient methadone initiation may be more effective than outpatient initiation.
In this episode Dr. Gillian Beauchamp sits down with Dr. Benjamin Hatten to discuss the potential role of psychedelics in palliative care medicine. Specifically data that shows improved outcomes in individuals who experience psychological stress related to a terminal or life limiting illness that is refractory to more traditional treatments such as antidepressants
In this episode Dr. Gillian Beauchamp sits down with Dr. Patil Armenian to discuss strategies to promote physiologic as well as well as mental/emotional/psychiatric safety when psychedelics are used therapeutically and recreationally.
In this episode Dr. Gillian Beauchamp sits down with Dr. Laurie Halmo discuss the challenges of making informed recommendations in regard to use of substances during pregnancy.
In this episode Dr. Gillian Beauchamp sits down with Dr. John Downs to discuss recommendations for at risk occupational PFAS testing (Aviation fire fighters, certain agricultural workers (exposure to “ bio sludge” , workers exposed to organofluorines, ski waxers) and challenges of generalized testing.
In this episode Dr. Gillian Beauchamp sits down with Dr. Albert Garcia Romeu to discuss the history of psychedelic use, current treatment protocols and research on using psychedelics to support recovery from substance use disorders.
In this episode Dr. Gillian Beauchamp sits down with Dr. Michael Twiner and Dr. Brett Johnson to discuss harmful algal blooms (HABs) such as inhalation toxicity from Red Tide, neurotoxic shellfish toxicity, diarrheal shellfish poisoning, and amnestic shellfish toxicity.
In this episode Dr. Gillian Beauchamp sits down with Dr. Michael Toce to discuss naloxone access laws, increased community availability of naloxone and who still doesn't have access to naloxone. They also discuss the difference between naloxone and nalmefene and the future of nalmefene.
In this episode Dr. Gillian Beauchamp sits down with Dr. Kevin Wenzel, PhD to discuss the importance of family involvement including identifying substance use disorder, seeking treatment and providing support during treatment.
In this episode Dr. Gillian Beauchamp sits down with Jonathan Jarry MSc to discuss trends in health related pseudoscience and our role in fighting misinformation.
In this episode Dr. Gillian Beauchamp sits down with Dr. Andrew Stolbach to discuss the mechanishm of action, toxicity and management of checkpoint inhibitors (immunotherapeutic agents used in the treatment of cancer).
intelligent ASIA & DIGITIMES & IC之音 聯合製播Live Studio主持人 李立達 Ft. ACMT協會理事長 蔡銘宏精彩重點:1. 分散生產蔚為主流!ACMT協會連結一萬多家台灣業者,深諳市場動態,為您分析美中貿易戰大環境下的模具與成型製造業發展趨勢,以及全球供應鏈如何變遷。2. 模具與成型產業95%靠技術與經驗,5%靠老師傅Knowhow。今天,AI與機聯網扮演哪些更積極的角色?3. 現在台商不缺工廠,缺訂單!中小企業跨區設廠風險高,如何透過公協會整合平台發展,引進AI技術、轉型智慧製造,讓台灣業者取得訂單,提供高品質產品?新型態智動化-Live Studio 直播間各場次精彩對談:9/2 17:00 全球節能科技與 AI 製造9/3 17:00 AIOT 賦能技術到自動化工廠9/4 17:00 產業設施永續發展 OT & IT 數位化整合解決方案9/5 17:00 線性移載設備與拖鏈在前沿領域應用9/6 17:00 強化彈性生產 - 機器人末端工具快換模組應9/9 17:00 未來工廠藍圖:工業 AI 運算與工業網路9/10 17:00 智慧成型專業顧問服務建構智慧化產業供應鏈9/11 17:00 工業 AI 如何有效提升製造創新9/12 17:00 改變從創新開始 共創智慧倉儲解決方案9/13 17:00 不懂 AI 也能成為工業 AI 專家,將資料變金礦找出企業獲利命題
intelligent ASIA & DIGITIMES & IC之音 聯合製播Live Studio主持人 李立達 Ft. ACMT協會理事長 蔡銘宏精彩重點:1. 分散生產蔚為主流!ACMT協會連結一萬多家台灣業者,深諳市場動態,為您分析美中貿易戰大環境下的模具與成型製造業發展趨勢,以及全球供應鏈如何變遷。2. 模具與成型產業95%靠技術與經驗,5%靠老師傅Knowhow。今天,AI與機聯網扮演哪些更積極的角色?3. 現在台商不缺工廠,缺訂單!中小企業跨區設廠風險高,如何透過公協會整合平台發展,引進AI技術、轉型智慧製造,讓台灣業者取得訂單,提供高品質產品?新型態智動化-Live Studio 直播間各場次精彩對談:9/2 17:00 全球節能科技與 AI 製造9/3 17:00 AIOT 賦能技術到自動化工廠9/4 17:00 產業設施永續發展 OT & IT 數位化整合解決方案9/5 17:00 線性移載設備與拖鏈在前沿領域應用9/6 17:00 強化彈性生產 - 機器人末端工具快換模組應9/9 17:00 未來工廠藍圖:工業 AI 運算與工業網路9/10 17:00 智慧成型專業顧問服務建構智慧化產業供應鏈9/11 17:00 工業 AI 如何有效提升製造創新9/12 17:00 改變從創新開始 共創智慧倉儲解決方案9/13 17:00 不懂 AI 也能成為工業 AI 專家,將資料變金礦找出企業獲利命題
intelligent ASIA & DIGITIMES & IC之音 聯合製播Live Studio:智慧成型專業顧問服務建構智慧化產業供應鏈
In this episode Dr. Gillian Beauchamp sits down with Dr. Joshua Trebach to discuss the benefits and drawbacks of utilizing social media to increase awareness and promote medical toxicity.
In this episode Dr. Gillian Beauchamp sits down with Dr. Filza Hussain to discuss transplant organ allocation in patients who have organ failure secondary to a suicide attempt.
In this episode Dr. Gillian Beauchamp sits down with Dr. Matthew Salzman discusses the complications associated with the use of illicit fentanyl containing xylazine from wounds to withdrawal.
In this episode Dr. Gillian Beauchamp sits down with Dr. Alan Wolfe to discuss the possible clinical effects of POPs (Persistent Organic Pollutants) and PFAS (Per and polyfluoroalkyl substances).
In this special episode of Dennis Anyone, Dennis is joined by five friends he's known since 1986 when he moved from Arizona to Los Angeles to take part in a 12-week long performing workshop put on by American Center for Musical Theater at held at the Dorothy Chandler Pavilion in downtown Los Angeles. This reunion meal happened in 2017 and was held at the Moorpark, CA home of Kristin Dahl and her husband Eric and the other attendees are Sherri Fleming, Karole Forman, Dennis Osborne and Jon Thomas. The group talks about what that intensive workshop meant for them in their lives and share what they remember about that time and each other. Other topics include: bad auditions, dream roles and teachers that hurl insults, play mind games and worse in order to toughen you up for show business.
In this episode Dr. Gillian Beauchamp sits down with Dr. Travis Olives to discuss gap junctions and cardiac effects of bupropion toxicity.
In this episode Dr. Gillian Beauchamp sits down with Dr. Stephanie Weiss to discuss HERG channel blockade, QTc prolongation and cardiotoxicity.
In this episode Dr. Gillian Beauchamp sits down with Dr. Meghan Spyres to discuss the evolution of antivenom treatment of North American Pit Viper envenomation with specific discussion of the differences between Fab (CroFab) and F(ab)2 (ANAVIP) antivenom.
In this episode Dr. Gillian Beauchamp sits down with Dr. Christian Tomaszewski to discuss risk factors for delayed cardiomyopathy and mortality after carbon monoxide exposure.
In this episode Dr. Gillian Beauchamp sits down with Dr. Alex Manini to discuss single nucleotide polymorphisms (SNPs) of the Mu receptor and how they may relate to overdose severity of opioid overdose.
In this episode Dr. Gillian Beauchamp sits down with Dr. Fiona Garlich to discuss mechanisms and clinical presentations of aconitine, veratrum alkaloid and grayanotoxin cardiotoxicity.
For most of us, responding to an inquiry of where we are from is an easy answer. Even if we have to move around within that country, we always are able to point to where our roots are laid down. This has not always been the case for Bonnie, this week's guest. Please join us as we learn about her childhood as the daughter of a proud Air Force man, the many different countries she lived in, the two seismic unexpected losses she experienced as an adult, and her current work in massage therapy assisting those dealing with mental health challenges.Bonnie Rose Aherin, ACMT, BTEC6Bonnie's dissertation title is: 'The Effects of the Online Jing Method™ of Advanced Clinical Massage on Mental Health in Adults' If you would like to register for the Online Clinical Research Conference, please visit: https://www.jingmassage.com/latest/online-clinical-massage-research-conference-20-7-23/ is a link to register for the Online Clinical Research Conference. Once registered you can watch live or watch the recording. Bonnie will be talking about her dissertation, research study and results at 1200 GMT on July 20th. Website: www.knotsology.comEmail: hello@knotsology.com@knotsology on Instagram, Facebook,Twitter, TikTok, YouTubeEditorial note: Sad Times is committed to sharing various stories from generous guests. The hope is to allow any number of stories to be shared to help people feel less alone and, perhaps, more empathetic. It is important to clarify that the guests' stories, perspectives, and sentiments do not necessarily reflect the views and beliefs of Sad Times in any waySad Times Website: www.sadtimespodcast.coFollow Sad Times on Facebook: https://www.facebook.com/groups/373292146649249Follow Sad Times on Instagram: @sadtimespodcast
In this episode Dr. Gillian Beauchamp sits down with Dr. Robert Haley to discuss Gulf War Illness and what caused over 100,000 people to become ill during and after the Gulf War. Dr. Haley describes the gene-environment interaction between PON-1 polymorphism and exposure to sarin gas.
In this episode Dr. Gillian Beauchamp sits down with Dr. Spencer Greene to discuss his recent case series of antimuscarninic delirium treated with rivastigmine in the setting of physostigmine shortages.
Apologies for being MIA for a month now. Been busy! But am back and in this episode talk about calcium channel blocker toxicity. The physiology behind it, a little pharmacology and then the treatment. Busting some myths and reinforcing the need for proactive emergency medicine evidence based treatment. You can check out these papers and do more research for yourselves too - 1. Wightman RSHRA. Cardiologic Principles II: Hemodynamics. In: Nelson LS, Howland MA, Lewin NA, et al, editors. Goldfrank's toxicologic emergencies. 11th Edition. New York City, NY: McGraw Hill; 2019. p. 260–7 2. Levine M, Brent. Beta-Receptor Antagonists. In: Brent J, Burkhart K, Daragan P, et al, editors. Critical care toxicology. New York City, NY: Mosby; 2017. p. 771–86. Wallukat G. The beta-adrenergic receptors. Herz 2002;27(7):683–90. 4. Ranniger C, Roche C. Are one or two dangerous? Calcium channel blocker exposure in toddlers. J Emerg Med 2007;33(2):145–54 5. Gummin DD, Mowry JB, Beuhler MC, et al. 2019 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 37th Annual Report. Clin Toxicol 2020;58(12):1360–541. 6. Holger JS, Engebretsen KM, Obetz CL, et al. A comparison of vasopressin and glucagon in beta-blocker induced toxicity. Clin Toxicol 2006;44(1):45–51 7. Jang DH, Donovan S, Nelson LS, et al. Efficacy of methylene blue in an experimental model of calcium channel blocker-induced shock. Ann Emerg Med 2015;65(4):410–5. 8. Laes JR, Williams DM, Cole JB. Improvement in hemodynamics after methylene blue administration in drug-induced vasodilatory shock: a case report. J Med Toxicol 2015;11(4):460–3. 9. Wang GS, Levitan R, Wiegand TJ, et al. Extracorporeal membrane oxygenation (ECMO) for severe toxicological exposures: review of the toxicology investigators consortium (ToxIC). J Med Toxicol 2016;12(1):95–9 10. Hayes BD, Gosselin S, Calello DP, et al. Systematic review of clinical adverse events reported after acute intravenous lipid emulsion administration. Clin Toxicol 2016;54(5):365–404 11. American College of Medical Toxicology. ACMT position statement: guidance for the use of intravenous lipid emulsion. J Med Toxicol 2017;13(1):124–5. 12. Kerns W 2nd. Management of beta-adrenergic blocker and calcium channel antagonist toxicity. Emerg Med Clin North Am. 2007 May;25(2):309-31; abstract viii. doi: 10.1016/j.emc.2007.02.001. PMID: 17482022. 13. Cole JB, Arens AM. Cardiotoxic Medication Poisoning. Emerg Med Clin North Am. 2022 May;40(2):395-416. doi: 10.1016/j.emc.2022.01.014. Epub 2022 Apr 5. PMID: 35461630.
In this episode Dr. Gillian Beauchamp sits down with Dr. Tricia Wright to discuss risk factors leading to methamphetamine use disorder, associated complications in pregnancy and management of substance use disorder in pregnant and postpartum patients.
In this episode Dr. Gillian Beauchamp sits down with Dr. Tricia Wright to discuss the known and theoretical risks of cannabis use during pregnancy and lactation.
In this episode Dr. Gillian Beauchamp sits down with Dr. Mishka Terplan to discuss stigma, discrimination and prejudice in relation to substance use in pregnancy.
We love taking the tradeshow live to the Aerospace Component Manufacturer's Aerospace Alley tradeshow! This episode was recorded with guests from the tradeshow floor and has all the energy you'd expect from a tradeshow. Ari starts out with the President of the Aerospace Components Manufacturer's organization, and President of ACMT, Inc, Michael Polo. Michael is so passionate about getting students involved in manufacturing and talks all about how they do that in the ACM and at ACMT, Inc as well. At 18:10 Jack Lukasik, President of Satellite Tool & Machine Co, Inc joins Ari to talk about the cool things they are making , the growth of the organization, and their new VP of Engineering. Finally, join Ari at 34:37 to hear Paul Surowaniec, General Manager of J&P Manufacturing, talk about their small, but growing turning shop, what it's like working with family, and his excitement about being at his very first ACM tradeshow. ACMT Inc: Company Website: https://acmt.aero/ Company LinkedIn: https://www.linkedin.com/company/adchem-manufacturing-technologies-inc-/ Michael's LinkedIn: https://www.linkedin.com/in/michael-polo-81260912/ Satellite Tool & Machine Co Company Website: http://www.satellitetoolmachine.net/ Company LinkedIn: https://www.linkedin.com/company/satellite-tool-machine-co-inc Jack's LinkedIn: https://www.linkedin.com/in/jack-lukasik-b50159127 J&P Manufacturing Company Website: https://jandpmanufacturing.com/ Paul's LinkedIn: https://www.linkedin.com/in/paul-j-surowaniec-21bb19167 Ari Santiago, CEO, CompassMSP Company Website: https://compassmsp.com/ Company Facebook: https://www.facebook.com/MadeinAmericaPodcast Company LinkedIn: https://www.linkedin.com/company/made-in-america-podcast-with-ari Company YouTube: https://youtube.com/c/MadeinAmericaPodcastwithAri Ari's LinkedIn: https://www.linkedin.com/in/asantiago104/ Podcast produced by Miceli Productions: https://miceliproductions.com/
In this episode Dr. Gillian Beauchamp sits down with Dr. Lori Devlin to discuss Neonatal Abstinence Syndrome (NAS), Neonatal Opioid Withdrawal Syndrome (NOWS) and the treatment of NOWS.
In this episode Dr. Gillian Beauchamp sits down with Dr. Kurt Kleinschmidt to discuss the differences between dependence, addiction, and substance use disorder and how it relates to medication associated treatment (MAT).
In this episode Dr. Gillian Beuachamp sits down with Assistant Chief of Police Matthew Myers to discuss the Drug Recognition Evaluation (DRE) and the Drug Influence Evaluation (DRE) assessments.
Michael Polo, Founder and President, of ACMT has a unique story leading him to manufacturing and an even better story of building ACMT! In this episode of the podcast, Mike shares his many stories with Ari to show that risk pays off, creativity wins, and trying the impossible can sometimes be your best bet. This rapid fire episode is full of fun and laughter that leads to some great manufacturing wisdom along the way. ACMT's Website: https://acmt.aero/ ACMT's LinkedIn: https://www.linkedin.com/company/adchem-manufacturing-technologies-inc-/ Michael's LinkedIn: https://www.linkedin.com/in/michael-polo-81260912/ Ari Santiago, CEO, CompassMSP Company Website: https://compassmsp.com/ Company Facebook: https://www.facebook.com/MadeinAmericaPodcast Company LinkedIn: https://www.linkedin.com/company/made-in-america-podcast-with-ari Company YouTube: https://youtube.com/c/MadeinAmericaPodcastwithAri Ari's LinkedIn: https://www.linkedin.com/in/asantiago104/ Podcast produced by Miceli Productions: https://miceliproductions.com/
In this episode Dr. Gillian Beauchamp sits down with Patrick Harding to discuss anterograde and retrograde ethanol calculations and how they are used in forensic toxicology.
In this episode Dr. Gillian Beauchamp sits down with Dr. Laura Tormoehlen to discuss the nuances of brain death declaration in the toxicology patient
In this episode Dr. Gillian Beauchamp sits down with Dr. Andrew Monte to discuss common nomenclature used in pharmacogenetics and pharmacogenetic factors that impact patient care in the ICU.
In this episode Dr. Gillian Beauchamp sits down with Dr. Brenna Farmer to discuss the process of gaining approval to use medications past their original expiration dates.
In this episode Dr. Gillian Beauchamp sits down with Dr. Donna Seger to discuss the clinical advantages of having a medical toxicologist at the bedside
Jeff and Greg attempt to chew through an opioid sammy and Greg ponders the collective childhood of test question writers
Jeff and Greg douse their inner Grinch with toxicologic goodness