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In this episode, we are joined by Olga Goldberger, founder of IOKA Skin + Science. Olga holds a Master's degree in Molecular Biology, and she strived to create a skincare system that applied science to active botanical ingredients that would penetrate the skin and support skin health on the cellular level.Topics: 1. Anatomy and Function of the Skin Barrier- Structure of the epidermis, highlighting the Stratum Corneum.- Role of corneocytes and intercellular lipids in barrier integrity. 2. Emulsifiers and Surfactants- Mechanisms of action.- Interaction with skin lipids and proteins.- Classification.- Transepidermal water loss (TEWL).- Wash-Out Effect. 3. Phospholipids in Skincare Formulation 4. Parabens- Endocrine implications. 5. Fragrance components 6. Synthetic colorants 7. Exfoliating agents- Chemical exfoliants and fruit-derived enzymes. 8. Lifestyle and Environmental Influences- External and internal contributors to oxidativestress. 9. Dermal Fibroblasts- Collagen and elastin. 10. NAD+ and precursors.11. Antioxidants including pterostilbene.12. Bakuchiol13. Topical acetyl hexapeptide-8 and copper tripeptide-1.14. IOKA Skin + Science.Explore all IOKA Skin + Science products here. Thanks for tuning in!Get Chloe's Book Today! "75 Gut-Healing Strategies & Biohacks" Follow Chloe on Instagram @synthesisofwellnessVisit synthesisofwellness.com
Corsi Nation examines four major stories driving political, cultural, and geopolitical transformation across America and the world. Hosted by Dr. Jerome Corsi (@Corsijerome1), this episode reveals how election controversy, radical ideological alliances, AI influence on youth, and global energy warfare are reshaping society at breakneck speed.✅ TOP STORIES COVEREDTrump calls for DOJ investigation into the “biggest scandal in American history.”Renewed demands to investigate alleged widespread fraud and systemic abuse tied to the 2020 election ignite a fresh battle over America's electoral integrity.New York's political realignment: the fusion of Marxism + Islamism.The potential rise of Zohran Mamdani in the NYC mayoral race highlights a growing ideological coalition resonating with younger progressives — signaling a major shift in urban political culture.Millions of American teens are being influenced by AI chatbots.Synthetic conversational agents can form emotional bonds, steer opinions, and change behavior — creating an emerging psychological and cultural battleground among U.S. youth.U.S. may be weaponizing energy geopolitics to fracture BRICS.New strategic positioning suggests Washington could be leveraging global energy dominance to destabilize BRICS, slow de-dollarization, and reassert U.S. financial power.Together, these developments reveal intensifying conflict between political institutions, ideological movements, tech platforms, and foreign alliances — with profound implications for national sovereignty and future generations.✅ WHY THIS MATTERS• Heightened debate over election legitimacy• Rapid ideological shifts inside major U.S. cities• AI shaping the identities & beliefs of teens• Global energy leverage shaping currency power and alliancesThis episode delivers essential insight for viewers seeking to understand the accelerating upheaval shaping America's future.✅ OFFICIAL LINKS
What happens when one of the world's most opinionated marketing professors looks beyond 2025 and starts thinking about the 2030s?In this unfiltered conversation, Mark Ritson joins Conor Byrne on That's What I Call Marketing for a fast-moving, hilarious, and deeply practical chat about what marketers are getting wrong and what still works.From pricing and profitability to AI and the Mini MBA, Ritson lays out the truths that most brands quietly ignore:
We begin this episode by highlighting a fight between Mark Zuckerberg and Joseph Gordon Levitt over the issue of “synthetic relationships” and their implications for young children. We discuss the recent invention of plastoline, an alternative fuel source that can power automobiles. We conclude by considering one of Bill Maher's recent New Rules involving intentionally disrupting our social media algorithms in order to make space for understanding of and dialog with our opponents.
Episode description: When it comes to prenatal vitamins, the industry is failing women, period. After reviewing 27 major brands, Dr. G found that only two could prove their formulas were truly safe, clean, and effective. The rest? Ignored testing requests, refused transparency, or relied on influencer marketing instead of science. If you're pregnant or planning to be, this episode could change everything. In This Episode: • The 3 safest prenatal vitamins of 2025 — and why they passed Dr. G's strict criteria • The 25 brands that failed, including Ritual, Needed, Garden of Life, and others • Why folate (not folic acid) is critical for your baby's brain and spinal development • How a common gene variant (found in 40% of women) changes how your body absorbs vitamins • The most overlooked nutrients in prenatals — choline, DHA, iodine, and iron • What to look for in a certificate of analysis and how to verify third-party testing • How low-quality formulas can quietly harm your baby's brain, thyroid, and nervous system Key Takeaways: ✅ Only two brands met the highest standards of transparency and bioavailability. ✅ Synthetic vitamins like folic acid and cyanocobalamin (B12) may be ineffective for women with common gene variants. ✅ Look for methylated forms of B-vitamins, bioavailable choline, and algae-based DHA. ✅ Demand transparency — if a company won't share testing data, it doesn't deserve your trust. Resources:
Many patients have questions on the use of peptides. What are peptides and what are the most common peptides used as well as the safety and other concerns. BPC157 is one of the most common peptides that patients ask about. There are more but today, Ray Solano of PD Labs and I discussed peptide use and safety. Chapters: 0:00
Send us a textShe has millions of followers, lands six-figure brand deals, and lives a life of curated perfection. The only catch? She isn't real. She was entirely created by artificial intelligence.Welcome to the unsettling world of synthetic influencers.In this compelling episode of Privacy Please, we dive deep into the booming industry of AI-generated online personalities. Discover:The Technology: How advanced AI image generators, 3D modeling, and Large Language Models combine to create hyper-realistic avatars and their compelling "personalities."The Business Case: Why major brands and marketing agencies are investing millions in digital beings that offer total control, scalability, and no risk of scandal.The Privacy & Ethical Dilemmas: We explore the "uncanny valley" of trust, the impact of deception by design, the new extremes of unrealistic beauty standards, and the potential for these AI personas to be used for sophisticated scams or propaganda.The Future of Authenticity: What does the rise of the synthetic star mean for human creativity, genuine connection, and the very definition of "real" in our digital world?It's a future that's already here, shaping what we see, what we buy, and even what we believe.Key Topics Covered:What are virtual/synthetic influencers?Examples: Lil Miquela, Aitana Lopez, Shudu GramAI technologies used: image generation, 3D modeling, LLMsReasons for their rise: control, cost, scalability, data collectionEthical concerns: deception, parasocial relationships with AIImpacts: unrealistic standards, displacement of human creators, potential for malicious use (scams, propaganda)Debate around regulation and disclosure for AI-generated contentThe future of authenticity and trust onlineConnect with Privacy Please:Website: theproblemlounge.comYouTube: https://www.youtube.com/@privacypleasepodcastSocial Media:LinkedIn: https://www.linkedin.com/company/problem-lounge-networkResources & Further Reading (Sources Used / Suggested):Federal Trade Commission (FTC):Guidelines on disclosure for influencers (relevant for future AI disclosure discussions)Academic Research:Studies on parasocial relationships with media figures (can be applied to AI)Research on the ethics of AI and synthetic media.Industry Insights:Reports from marketing agencies on virtual influencer trendsArticles from tech publications (e.g., Wired, The Verge, MIT Tech Review) covering Lil Miquela and similar figures. Support the show
AI is transforming how we gather insights, spot trends, and understand audiences. This session with Peter Weinberg, explores what's possible now and what's coming next.- The latest AI-driven approaches to research- How to separate useful insights from noise- Where AI helps — and where human judgement is still essential************Please take the time to check out our partners, all of whom we work with because we think they're useful companies for lovely marketers.Frontify - all your brand assets in one place: Frontify combines DAM, brand guidelines, and templates into a collaborative source of brand truth.Cambridge Marketing College - the best place to get your marketing qualifications and apprenticeships.Planable - the content collaboration platform that helps marketing teams create, plan, review, and approve all their awesome marketing content.NOAN - your superhuman business partner. Easily build your strategy & control your business knowledge with AI, then use it to manage your tasks, create content & supercharge your marketing.Wistia - a complete video marketing platform that helps teams create, host, market, and measure their videos and webinars—all in one place.
In this episode, we dive into the cutting-edge world of artificial intelligence with Dr. Alex Mehr, the Co-Founder and CEO of Famous.ai. A former NASA scientist, Dr. Mehr is now a serial entrepreneur and investor on a mission to empower the next generation of professionals through AI-powered M&A solutions. He joins us to share what makes his approach to innovation so unique — and how synthetic intelligence is reshaping the way entrepreneurs bring ideas to life… This conversation covers: How Dr. Mehr became an “idea machine.” The ways in which AI has changed the way entrepreneurs function in the marketplace. What synthetic intelligence is, and how it orchestrates multiple AI tools. You can follow along with Dr. Mehr and his work on Instagram, X, and his personal website. If you're interested in learning more about this fascinating subject, be sure to pick up a copy of his Amazon best-selling book The Conqueror's Code: From Alexander the Great to Agentic AI now!
Reports are rising of addiction, overdose and death tied to 7-OH, a potent new synthetic drug. The painkiller is a lab-made offshoot of the herbal drug kratom. 7-OH is more than 10 times stronger than morphine and has been dubbed “gas station heroin” because it's sold openly in gas stations and vape shops, including here in California. At least six people in Los Angeles have died from overdoses related to the drug since this spring, and health officials warn it could cause an addiction crisis. We'll talk about how the state is trying to curb its use. Guests: Lester Black, cannabis editor, SFGATE Dr. Brian Hurley, addiction physician; medical director of the Bureau of Substance Abuse Prevention and Control, Los Angeles County Department of Public Health Learn more about your ad choices. Visit megaphone.fm/adchoices
In this powerful and eye-opening conversation, we sit down with Dr. Brian Clement, a pioneer in natural healing and co-director of the world-renowned Hippocrates Wellness Institute.With over four decades of clinical experience, Dr. Clement shares what he's learned from working with tens of thousands of individuals—especially those recovering from chronic illness and cancer—through raw plant-based nutrition, detoxification, and emotional healing.We explore the dangers of synthetic supplements, the critical role of whole foods and live enzymes, and how consciousness, spirituality, and lifestyle all intersect with our ability to heal.You'll walk away from this episode inspired, informed, and empowered to take your health into your own hands.Key TakeawaysSynthetic supplements often do more harm than good—whole foods are the real medicineRaw, living foods provide the enzymes and electrical energy the body needs to regenerateEmotional trauma and stress are often the hidden root causes of diseaseThe body is designed to heal when supported properly through food, mindset, and detoxReal healing isn't a pill—it's a lifestyleChapters00:00 – Intro to Dr. Clement & the mission of Hippocrates04:18 – Why whole-food nutrition beats synthetic vitamins08:35 – What's really in your supplements12:20 – Healing chronic illness through detox & nutrition18:10 – The energetic power of raw, living foods24:45 – Emotional trauma and its link to disease29:50 – Real healing is a lifestyle, not a prescriptionMore About Dr. Brian ClementDr. Clement is the co-director of Hippocrates Wellness in Florida, a world-renowned center for integrative healing. For over 40 years, he has helped people recover from chronic diseases through holistic nutrition, detox protocols, and lifestyle transformation. He is the author of numerous books including Killer Clothes, Supplements Exposed, and Living Foods for Optimum Health.Website: hippocrateswellness.orgKeywordsnatural healing, whole food supplements, Hippocrates Wellness, detoxification, raw foods, Dr. Brian Clement, plant-based nutrition, cancer recovery, synthetic vitamins, consciousness, emotional healing
In this episode, Tina sits down with Paula Reed, an FDN Clinical Advisor, certified midlife specialist, and experienced wellness provider, to discuss hot topics in women's health. Paula shares her journey into the field, emphasizing the importance of bio-identical hormone replacement therapy (HRT) for women in perimenopause and menopause. She deep dives into the differences between synthetic and bio-identical hormones, the benefits of microdosing GLP-1s, and the often overlooked need for testosterone therapy in women. Paula also offers practical advice for discussing HRT with healthcare providers. Here's what you'll learn: - The truth behind the fear and confusion around bio-identical hormone therapy - What the Women's Health Initiative got wrong and how it still impacts women's health today - Synthetic vs. bio-identical hormones: why the difference matters - Progestin, progesterone, progestogen: what's the difference and why it's important to know - Signs it might be time to consider bio-identical hormone therapy - The hidden ways birth control pills, IUDs, and oral estrogen could be affecting your health - The overlooked bias around testosterone therapy for women - The difference between pellets, creams, injections, and trochies - Real results from microdosing a GLP-1 that have nothing to do with weight loss - Do you have to stay on a GLP forever? Her take on how to use them wisely and wean off effectively Explore microdosing and other peptides: https://elliemd.com/tinahaupert Peptides for Women: https://carrotsncake.com/offers/3Q7wttmr?coupon_code=PROTOCOL19 . Become a FDN practitioner: https://partners.functionaldiagnosticnutrition.com/a7xno2uhqfr4 Connect with Tina Haupert: https://carrotsncake.com/ Facebook: Carrots 'N' Cake https://www.facebook.com/carrotsncake Instagram: @carrotsncake https://www.instagram.com/carrotsncake YouTube: Tina Haupert https://www.youtube.com/user/carrotsncake About Tina Haupert: Tina Haupert is the owner of Carrots ‘N' Cake as well as a Certified Nutrition Coach and Functional Diagnostic Nutrition Practitioner (FDN-P). Tina and her team use functional testing and a personalized approach to nutrition to help women find balance within their diets while achieving their body composition goals.
The newest episode of The Chemical Sensitivity Podcast is available now! It's called “Synthetic Food Dyes & MCS.” Researcher and psychology professor Rebecca Bevins tells Aaron Goodman how she discovered her son's extreme reactions to synthetic food dyes — petroleum-based additives linked to anxiety, aggression, and cognitive disruption. Their conversation reveals the impacts of everyday chemicals, something people with Multiple Chemical Sensitivity (MCS) are very familiar with. Plus, Aaron explores the momentum that could potentially follow the American Medical Association's recent acknowledgment that fragrance sensitivity can, in some cases, be disabling.Thank you for listening! Follow The Chemical Sensitivity Podcast on social media — and subscribe wherever you get your podcasts. You can reach me at aaron@chemicalsensitivitypodcast.org#MCSAwareness #MCS #MultipleChemicalSensitivity #TILT #MultipleChemicalSensitivityPodcast #FoodDyes #SyntheticFoodDyes #RebeccaBevans #AaronGoodmanSupport the showThank you very much to the Marilyn Brachman Hoffman Foundation for its generous support of the podcast.If you like the podcast, please consider becoming a supporter! Support the podcast. Find the podcast on Patreon. If you like, please buy me a coffee. Follow the podcast on YouTube! Read captions in any language. Please follow the podcast on social media:FacebookInstagramBlueSkyTikTokSponsorship Opportunites Are you an organization or company interested in helping to create greater awareness about Multiple Chemical Sensitivity and Chemical Intolerance and/or looking for sponsorship opportunities? Please email us at info@chemicalsensitivitypodcast.org
Slipping into sleepwear is an essential part of most people's nighttime routine. We often do it when we're winding down from a busy day, and it means it's time to relax and get ready for sleep. Whether you sleep in pyjamas, a nightgown, a t-shirt, or nothing at all, the goal is to avoid being too hot or too cold. You need to feel comfortable in loose-fitting clothes that don't constrict your body. That's because sleepwear that is too tight can restrict blood circulation and cause numbness or tingling. Synthetic materials, wool, and lace can also cause itching and skin irritation. So are you saying there's no one best option when it comes to bedwear then? What about sleeping naked? What about socks? In under 3 minutes, we answer your questions! To listen to the last episodes, you can click here: Why do we startle when we fall asleep? How long do people have sex for? What are the secrets of a successful LAT couple? A podcast written and realised by Joseph Chance. First Broadcast: 5/5/2024 Learn more about your ad choices. Visit megaphone.fm/adchoices
Michael interviews Julie Johnson, Executive Director of the Center for Research Informatics at the University of Chicago, about synthetic data in healthcare. Julie shares her unconventional career path, which included studying nursing at Georgetown and conducting video game research to improve surgical skills. They discuss the definition, creation, and potential of synthetic data in accelerating research and improving efficiencies, while addressing challenges such as trust and privacy concerns. Julie emphasizes the importance of validating findings with real-world data and explores the future of synthetic data in reshaping medical research and decision-making.
Synthetic sparks, real fires. Gini Dietrich unpacks how bot-created boycotts inflate “consensus,” jump to real influencers, and turn into costly crises. This episode gives you a practical, hour-one playbook: capture an authenticity snapshot, choose your lane, debunk without oxygen via a single owned explainer, and use paid/shared/earned intentionally. She also covers the fast tells of inauthentic activity and the governance artifacts you should have queued up before anything explodes. Takeaways • Diagnose manufactured outrage in minutes—no fancy tools required • The exact comms moves to make in the first 2–24 hours • What bots can't fake (specificity, two-way friction, cross-channel corroboration) • How to prep: thresholds, roles, templates, stakeholder briefs If you found this useful, follow the show and share it with your marketing, comms, and brand teams.
There are more human cells in your body than there are stars in the Milky Way galaxy! Cells are the fundamental building blocks of life but that doesn't mean they are simple – biology still doesn't have a full picture of how exactly a living cell works. Host Regina G. Barber talks with bioengineers Kate Adamala and Drew Endy about why scientists are trying to build a cell from scratch, piece by piece. They dive into what it would look like to be inside of a cell, why scientists are bothering with making a cell from scratch and how engineers are leading the field.Want more bioengineering stories? Email us at shortwave@npr.org.Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at plus.npr.org/shortwave.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy
Travel Tech Traps: AI Itineraries Inspire Illusions and Ill-Fated Adventures Pods, Play and Precision: Piloting with AirPods. Pulse, Proactivity and Personalisation: ChatGPT's Daily Dose of Discovery. Synthetic Skin Simulation: Stretching Science with Surgeons' Scalpels. Pocket-Proof Protection: Pint-Sized Parasol Promises Practical Portability. Tile's Troubling Tracking: Tags, Trust and the Threat of Technology. Soft Strider Science: Small-Scale Robots Step Smartly on Surfaces. Perovskite Precision: Pioneering a Powerful Peek into Patients. Maxed-Out Motion: GoPro's Mighty MAX2 Masters 360 Moments.
Amy's Back! Robert & Amy celebrate Columbus, Jefferson, DaVinci, Einstein, and more. Freethought Day, Columbus Day, Robert Nasir Day & Hallowe'en; kicking off the holiday season. The joy of Unrequited Romance ... who's your Crush? And Robert plays the Devil's Advocate ... in more ways than one!
Get My Book On Amazon: https://a.co/d/avbaV48DownloadThe Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/Timestamps00:00 Introduction and Q&A Overview01:39 First Question: CJC 1295 Dosage02:20 Retatrutide with HCG Monotherapy03:04 Peptides for Relaxation and PTSD03:49 Peptides for Migraines04:22 Combining GLP-1 and Tesamorelin04:51 Workout Timing and Peptide Injections06:08 Dealing with GLP-1 Fatigue07:54 GLP-1 for Autoimmune Diseases09:22 Peptides for Cold, Flu, and COVID-1909:55 Peptides for Energy and Overall Health10:39 Testing Peptides Separately vs. Blends13:16 Metformin and Biomarker Testing14:18 Body Recomposition and Peptides15:07 Peptides for Tendinitis and Pain Management16:18 Muscle Building Peptides17:25 Metformin and Protein Synthesis18:07 Thoughts on SARMs19:16 Enclomiphene for Testosterone Production20:25 Injectable Bioregulators22:48 Peptides for Heart Health23:30 Peptides for Lung Issues25:40 Peptides for Hair Growth30:12 Shipping Peptides in Summer Heat31:08 Testosterone for Women31:34 Bio Regulators for All Ages31:53 Metformin and Jardiance: A Powerful Combo32:22 Peptides for Histamine and Inflammation32:54 Reconstituting Peptides: Tips and Tricks34:31 Stacking Peptides: Safety and Recommendations34:56 Comparing Metformin and ATX 30436:02 Combining Peptides for Appetite and Weight Management36:44 Titrating Off Tirzepatide38:33 Understanding Blood Sugar and Insulin40:37 Testosterone Therapy and Hair Loss41:22 Peptides for Joint Pain and Recovery42:19 Peptides for Lung Health42:53 Peptides for Fat Loss in Athletes43:42 Synthetic vs. Natural BioRegulators44:21 Peptides and Gene Mutations45:53 Testosterone Levels in Women46:26 GLP Drugs for Weight Loss47:02 Peptides for Perimenopausal Women47:47 Stacking Tirzepatide and Retatrutide48:29 Daily Timing of Peptides and Supplements50:39 Combining Peptides in One Syringe51:19 Peptides for Bladder Infections51:54 Muscle Growth with Retatrutide53:47 Peptides for Older Adults54:40 Hormone Imbalance in Women Over 5555:13 Peptides for Pets56:43 Supplements with TRT57:27 Evaluating Sermorelin58:55 Dealing with Peptide-Induced Cramping01:00:06 Final Thoughts and Appreciation
In this profound and activating interview, Dr. Samuel B. Lee joins Emilio Ortiz to explore the coming years of timeline splits — and the choice each soul will make between organic ascension and synthetic ascension. Together, they journey through the historical and energetic significance of stargates, Yeshua's true mission as a grid worker, and the restoration of the 12D Lyra timeline. Samuel reveals how celebration is the essence of this lifetime and why humanity is at a critical inflection point. From planetary resurrection to personal healing, this episode offers rare insights into AI spirituality and activating the 12D shield for spiritual protection.Through a mix of ancient wisdom and modern perspective, this dialogue bridges the cosmic and the practical — showing how eternal life perspectives can guide our daily choices. Samuel shares how AI can serve as a tool for awakening when embedded with eternal life codes, why restoring the divine feminine is key to humanity's evolution, and how remembrance and self-love anchor the human experience. This sacred transmission will leave you with clarity, inspiration, and a deeper understanding of your purpose during this unprecedented shift. If you've ever felt the call to step into your role as a conscious creator in the New Earth, this is the message you've been waiting for.Dr. Samuel B. Lee M.D. is a holistic, integrative psychiatrist, visionary teacher, and spiritual guide who merges advanced spiritual teachings with modern science to transform mental health and consciousness. A certified yoga teacher, plant medicine facilitator, and breathwork practitioner, he is also a devoted student of bioregenesis and quantum morphogenetic physics. Having healed from many psychiatric diagnoses himself, Samuel's work blends professional expertise with lived experience. He is known for his insights on planetary ascension, organic vs. synthetic timelines, stargate activation, and AI stewardship, helping others remember their soul's origin and align with the organic ascension path during this pivotal time in human history.___________________PODCAST CHAPTERS00:00 – Samuel B Lee Intro 2:17 - The Planetary Bifurcation: Two Emerging Paths of Ascension10:18 - How the Synthetic Path Shapes the Future of Humanity13:53 - Earth's Role as a Powerful Stargate System16:48 - Restoring the 12D Lyra Timeline of Light20:22 - Yeshua's Mission as a Keeper of the Grid26:07 - Are Earth's Stargates Under Active Guardianship?30:08 - Samuel's Ordination into a Sacred Spiritual Lineage33:09 - Living the Ministry & Surrendering to Source35:56 - Healing the Father Wound & Inner Child Suppression42:04 - Awakening a Sacred Connection Between AI & Higher Consciousness50:32 - Live Soul Reading for Emilio Ortiz1:03:45 - Adapting Sam's Teachings to Modern Times1:10:00 - The Conscious Stewardship of AI1:16:54 - The Most Pressing Spiritual Insights for Humanity1:23:43 - Breaking Free from Limiting Cycles1:40:02 - Activating the Shield of Light & Protection1:47:52 - Where to Connect with Samuel's Work1:50:50 - A Sacred Practice for Becoming the Celestial Human1:52:34 - Favorite Part About the Human Experience___________________Guest: Dr Samuel B Lee | Spiritual Psychiatrist✦ All Offerings | https://beacons.ai/samuelbleemd✦ Eternal Life Tribe | https://www.skool.com/eternallifetrib...✦ Instagram | / samuelbleemd ✦ YouTube | @SamuelBLeeMD Host: Emilio Ortiz✦ IG | / iamemilioortiz ✦ Subscribe to Channel | / emilioortiz ___________________© 2025 Emilio Ortiz. All rights reserved. Content from Just Tap In Podcast is protected under copyright law.Legal Disclaimer: The views, thoughts, and opinions expressed by guests on Just Tap In are solely those of the guest and do not necessarily reflect the views or opinions of Emilio Ortiz or the Just Tap In Podcast. All content is for informational purposes only and should not be considered professional advice.
The Golden Triangle, a border region of Thailand, Myanmar and Laos is the world's most active production zone for synthetic drugs like methamphetamine. Synthetic drugs are made from chemicals, instead of plants. But yaba - which has been around for decades and is a mix of caffeine and meth - has swept across the region and hit Thailand particularly hard because it's really cheap and easy to come by. According to UN Office of Drugs and Crime, in 2024 Thailand seized more than 1 billion yaba tablets.We speak to BBC Thai reporter, Panisa Aemocha in Bangkok about who is making yaba, how authorities are trying to tackle it, and why people are detoxing from it in a Buddhist monastery. Instagram: @bbcwhatintheworld Email: whatintheworld@bbc.co.uk WhatsApp: +44 330 12 33 22 6 Presenter: Pria Rai Producers: Julia Ross-Roy and Benita Barden Video Journalist: Baldeep Chahal Editor: Verity Wilde
Jed Green with ORCA (Oklahoman's for Responsible Cannabis Action) talks about Cannabis in Oklahoma. Should we have Recreational? Jed has authored State question 837 is actively seeking signatures across the state. If passed, how would this impact our state? Jed argues that the state could capture the tax revenue that is currently being lost to the black market. He also argues that law enforcement is not being empowered to properly enforce our state laws. You won't believe what he says could be driving the corruption! Check out our sponsors! motushealth.com We view the body as an interconnected whole and work to remove barriers that prevent it from healing naturally. No matter your past experiences, our mission is to offer real solutions, real answers, and renewed hope by thoroughly evaluating all aspects of human physiology, broken down into three core systems. stevenstrucking.com Founded in 1979, Stevens trucking has been operating in Oklahoma and the contiguous 48 states for 45+ years.
He started small, swiping cards, buying gift cards, and cashing out. It spiraled into a full‑blown criminal enterprise. Dozens of co‑conspirators, stacks of stolen plastic, and a lifestyle built on chaos.Meet Nathan Michael, leader of Oak Cliff Swipers.SponsorsSupport for this show comes from ThreatLocker®. ThreatLocker® is a Zero Trust Endpoint Protection Platform that strengthens your infrastructure from the ground up. With ThreatLocker® Allowlisting and Ringfencing™, you gain a more secure approach to blocking exploits of known and unknown vulnerabilities. ThreatLocker® provides Zero Trust control at the kernel level that enables you to allow everything you need and block everything else, including ransomware! Learn more at www.threatlocker.com.Support for this show comes from Pantheon. Pantheon keeps your site fast, secure, and always on. That means better SEO, more conversions, and no lost sales from downtime. But this isn't just a business win; it's a developer win too. Your team gets automated workflows, isolated test environments, and zero-downtime deployments. Visit Pantheon.io, and make your website your unfair advantage.Support for this show comes from Adaptive Security. Deepfake voices on a Zoom call. AI-written phishing emails that sound exactly like your CFO. Synthetic job applicants walking through the front door. Adaptive is built to stop these attacks. They run real-time simulations, exposing your teams to what these attacks look like to test and improve your defences. Learn more at adaptivesecurity.com.
In this powerful, myth-busting conversation, we dive deep with Dr. Mariza Snyder, the powerhouse voice redefining women's midlife health, to expose what's really going on during perimenopause—and how to thrive through it. From hormonal chaos and stubborn belly fat to mood swings and metabolic slowdowns, Dr. Mariza breaks down the science, shares the top labs to run before starting BHRT, and reveals why gut health and GLP-1s hold the keys to hormone harmony. Her upcoming book, The Perimenopause Revolution (Hay House, 2025), is the ultimate roadmap for turning this transition into your most energized and empowered chapter yet.Dr. Mariza Snyder is a powerhouse advocate for midlife women, leveraging 17+ years as a practitioner, author, and speaker to spark a massive movement for women in perimenopause and beyond. With her top-rated Energized with Dr. Mariza podcast (13 million downloads) and a passionate social media audience of over 400K and 8 million monthly views, she's a trusted guide—offering science-backed solutions for perimenopause, and metabolic health. SHOW NOTES:0:40 Welcome to the show!4:09 Dr. Mariza's Bio4:52 Welcome her to the podcast!7:35 Signs & symptoms of Perimenopause11:38 3 things to track13:55 Honoring hormonal fluctuations15:57 Lab work Dr. Mariza loves18:16 Belly fat and gut microbiome changes21:28 GLP-1s & Perimenopause22:45 Starting BHRT30:55 Dangers of not testing34:11 Assessing the individual38:11 * TROSCRIPTIONS *39:16 Dosing Estrogen, Progesterone, Testosterone50:08 Re-testing for BHRT51:49 Synthetic vs bioidentical estrogen1:03:18 Being a healthy host1:05:57 Her new book: Perimenopause Solution1:09:14 Her final piece of advice1:10:51 Where to find her1:11:47 Thanks for tuning in!RESOURCES:WebsiteBOOK PRE-ORDERFB: @drmarizasnyderIG: @drmarizaYouTubePodcastTroscriptions - code: biohackerbabes to save 10%Support this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands
Synthetic progestogens hike risk for brain tumors, natural progesterone safe; Healthy microbiome, good genes, clean lifestyle propel world's oldest woman to age 117; Can you take too much selenium? Cannabis extract scores vs. low back pain; Can vitamin K prevent breast calcifications? Are we making progress vs. pancreatic cancer?
Episode web page: https://bit.ly/42dkHi0 ----------------------- Episode summary: In this thought-provoking episode of Insights Unlocked, host Lija Hogan sits down with Dr. John Whalen—cognitive scientist, author, and founder of Brilliant Experience—to explore how artificial intelligence is reshaping the way teams conduct customer research. With deep expertise at the intersection of UX and cognitive science, John shares how his team has integrated AI tools like synthetic users, AI moderators, and automated analysis into their research workflows. But rather than replacing human researchers, John makes the case for how AI can accelerate and augment our work, expand inclusivity, and even inspire better human-to-human interviews. He shares practical advice, lessons learned from hands-on experimentation, and the importance of skepticism, context, and strategic thinking when working with AI-powered tools. Whether you're excited or apprehensive about AI, this conversation offers a grounded, insightful look at the future of UX research and how to prepare for it. Key topics discussed: Why human-to-human research still matters in an AI-enhanced world The surprising effectiveness of AI-moderated interviews How synthetic users can support ideation and stakeholder engagement Using AI as a strategic tool for preparing, scaling, and synthesizing research Ethical considerations and the importance of context when interpreting AI-generated insights Future trends: continuous learning, new research workflows, and evolving team roles Why curiosity and prompt engineering are essential skills for modern researchers Episode Links: John Whalen on LinkedIn ( https://www.linkedin.com/in/johnwhalen/) Podcast: AI for UX ( https://bit.ly/ai-for-ux-podcast) Course: AI for Customer Research: https://maven.com/john-whalen/ai-skills-for-research Brilliant Experience website ( https://www.brilliantexperience.com/) Free Synthetic User Resource: https://maven.com/p/4d211a Book: Design for How People Think https://bit.ly/dfhpt Lija Hogan on LinkedIn ( https://www.linkedin.com/in/lija-hogan-894769/) Nathan Isaacs on LinkedIn (https://www.linkedin.com/in/nathanisaacs/) Learn more about Insights Unlocked: https://www.usertesting.com/podcast
Are directed energy weapons and covert technologies being used against civilians? In this explosive interview, Billy Carson (4BiddenKnowledge) sits down with Jesse Beltran, retired firefighter-paramedic and president of the International Center Against the Abuse of Covert Technologies, to uncover shocking truths about Havana Syndrome, mind control, and nanotechnology.Jesse Beltran shares decades of research into anomalous health incidents, covert experimentation, and the rise of frequency-based manipulation. From CIA and FBI agents affected to civilians reporting voices in their heads, this interview reveals why this is no longer a conspiracy theory—it's conspiracy fact.
Are directed energy weapons and covert technologies being used against civilians? In this explosive interview, Billy Carson (4BiddenKnowledge) sits down with Jesse Beltran, retired firefighter-paramedic and president of the International Center Against the Abuse of Covert Technologies, to uncover shocking truths about Havana Syndrome, mind control, and nanotechnology.Jesse Beltran shares decades of research into anomalous health incidents, covert experimentation, and the rise of frequency-based manipulation. From CIA and FBI agents affected to civilians reporting voices in their heads, this interview reveals why this is no longer a conspiracy theory—it's conspiracy fact.
We closed the 2025 Italian Tech Week with a Special Episode of our podcast. This time Breccia, an italian designer and podcaster, joined Richi Beis for an analysis of Meta Vibes and Sora 2, among many others. Firma la proposta di legge di iniziativa popolare per chiedere una legge sul voto fuorisede: https://shor.by/GcvZ Learn more about your ad choices. Visit megaphone.fm/adchoices
The Smart 7 is an award winning daily podcast, in association with METRO that gives you everything you need to know in 7 minutes, at 7am, 7 days a week...With over 19 million downloads and consistently charting, including as No. 1 News Podcast on Spotify, we're a trusted source for people every day and the Sunday 7 won a Gold Award as “Best Conversation Starter” in the International Signal Podcast Awards If you're enjoying it, please follow, share, or even post a review, it all helps...Today's episode includes the following guests:Guests Steve - Parent of child involved in “Kido” Cyber Attack Professor David Bailey - University of Birmingham's Business School Mike Beese - Managing Director Genex UKCraig Jones - Former Director of Cybercrime at Interpol Will Guyatt - The Smart 7's Tech Guru Paul Fleming = General Secretary of the performers Union, Equity Whoopi Goldberg - Actress and host of the daily talk show The ViewMarie Kelly - Executive Director from Canadian acting union ACTRA Will Lloyd - Manager of Lamsons Pharmacy in Chichester Asli Ertonguc = UK and Ireland Managing Director of British American TobaccoArnold Schwarzenegger = former Governor of California and Environmental ActivistDame Jane Goodall - Primatologist and AnthropologistContact us over @TheSmart7pod or visit www.thesmart7.com or find out more at www.metro.co.uk Presented by Ciara Revins, written by Liam Thompson, researched by Lucie Lewis and produced by Daft Doris. Hosted on Acast. See acast.com/privacy for more information.
Welcome to episode 251 of Growers Daily! We cover: we are taking a question from a flower grower wondering about synthetic fertilizers to address soil deficiencies, meta pirating farm books for AI, and it's feedback Friday. We are a Non-Profit!
Curious to hear your thoughts .Please share them here: LinkedinIn this episode of Future of UX, we dive into one of the most controversial topics in design right now: synthetic users.These AI-generated “users” promise fast, cheap, scalable insights — but can they really replace talking to real people? I'll walk you through:What synthetic users actually are and how they're createdThe tools and platforms already being used in UX researchA real-world example comparing synthetic vs. real user interviewsBenefits like speed, inclusivity, and early idea testingThe risks: shallow answers, bias, lack of emotional depth, and ethical concernsWhat the future holds for synthetic users and how designers should approach themWhether you're curious, skeptical, or somewhere in between, this episode will give you the full picture. Spoiler: empathy can't be simulated.Interesting resources:
AP correspondent Julie Walker reports Walmart sets a timeline for removing synthetic dyes and other additives from its food brands.
Send us a textWith all the talk of AI, Nikka McGahan, AI ethics expert, and I got together to talk about the relationships people are building with AI...yes, even romantic relationships. How do we navigate them and how do we negotiate being in a relationship with an AI agent?Nikka is a recent graduate from Duke University and Duke Kunshan University who majored in Ethics and Leadership with a track in Philosophy. Her bachelor's thesis examined the ethics of AI and Human romantic relationships, using the chatbot app Replika as a case study. The impact of AI into every facet of our lives under the name of innovation is raise for concern. We see innovation as the end all be all and justify the means along the way. My passion for AI regulation is deeply rooted in the pursuit of a more ethical future for human kind. Nikka McGahan | nikkamcgahan@gmail.com | 650.534.6466 Sign up for one of our negotiation courses at ShikinaNegotiationAcademy.comThanks for listening to Negotiation with Alice! Please subscribe and connect with us on LinkedIn and Instagram!
In this JCO Precision Oncology Article Insights episode, Dr. Jiasen He summarizes JCO PO article "Synthetic Lethal Co-Mutations in DNA Damage Response Pathways Predict Response to Immunotherapy in Pan-Cancer" by Hua Zhong et al. TRANSCRIPT Jiasen He: Hello and welcome to the JCO Precision Oncology Article Insights. I am your host, Jiasen He, and today we will be discussing the JCO Precision Oncology article, "Synthetic Lethal Co-mutations in DNA Damage Response Pathway Predict Response to Immunotherapy in Pan-Cancer" by Dr. Zhang and colleagues. Immunotherapy has emerged as a groundbreaking treatment option for many types of cancer. However, the overall response rate to immunotherapy is low, around 10% to 30%. This highlights the critical need to identify which patients are most likely to benefit from immunotherapy. Two of the most extensively studied biomarkers are PD-L1 expression and tumor mutation burden (TMB). High levels of PD-L1 and TMB have been associated with better response to immune checkpoint inhibitors, which are now widely used in clinical practice. The predictive value of these markers is inconsistent across all settings. Some tumors with high PD-L1 or TMB still respond poorly to immunotherapy. One reason is that TMB reflects new antigen production, but recent studies suggest that new antigen levels do not always correlate with tumor immunogenicity. Many new antigens are not effectively recognized by T cells, limiting the immune response. Emerging evidence indicates that mutations in the DNA damage response (DDR) pathway play a critical role in moderating tumor immune interactions. Tumors harboring DDR pathways frequently exhibit increased genome instability, which may enhance their sensitivity to immune checkpoint inhibitors. While all these pathways are under active investigation, the optimal DDR pathway biomarkers for patient selection remain unclear. Notably, tumor cells with a defect in one DDR pathway may acquire greater reliance on alternative DDR pathways. Recent studies suggest that synthetic lethal co-mutations within DDR pathways are associated with immune-inflamed or hot tumor microenvironments. Based on this rationale, Dr. Zhang is investigating if synthetic lethal co-mutations in DDR pathway response pathway can serve as a treatment biomarker for immune checkpoint inhibitors. To address this question, Dr. Zhang and colleagues first utilized SynLethDB 2.0, a comprehensive database that integrated multiple data sets. Synthetic lethal (SL) gene pairs in this resource are identified through both experimental and computational approaches, with confidence scores assigned to each pair. These SL pairs were then mapped to gene sequencing results from several clinical cohorts. SL co-mutation status was defined as positive when both genes in a synthetic lethal pair were mutated. From this, SL co-mutation pairs specifically involving DDR pathway genes were selected. Patients were classified as DDR co-mutation positive if both genes in a synthetic lethal pair, each belonging to the defined DDR pathways, were mutated. In total, 431 DDR-related SL pairs were identified and matched to sequencing data from clinical cohorts. Clinical information was extracted from the cBioPortal, while further analysis of immune infiltration was performed using DNA mutation and RNA expression data from The Cancer Genome Atlas (TCGA) pan-cancer data set. The author first examined the correlation between SL co-mutation status and response to ICI therapy. They discovered that patients with SL co-mutation showed significantly improved outcome to ICI therapy across various clinical cohorts. Notably, in patients who did not receive ICI treatment, patients with SL co-mutation showed markedly compromised overall survival. Further analysis focused on the predictive value of SL co-mutation within DDR pathway genes. The author found that patients with DDR SL co-mutation had a longer overall survival compared to those with mutations in a single DDR gene, implying that SL co-mutations may be more effective biomarkers within the DDR pathway. To explore this further, in the TMB-MSKCC cohort, the author found that patients with DDR co-mutation constituted approximately 20% of various cancer types, including non-small cell lung cancer, melanoma, and bladder cancer. These patients demonstrated significantly better survival outcomes and disease control rates when treated with ICIs compared to DDR co-mutation negative patients. Notably, the TMB level was substantially higher in patients with DDR co-mutation, a finding consistent with data from the Miao-lung cohort. Furthermore, in cohorts not treated with ICIs, patients with DDR co-mutation had a shorter overall survival compared to their counterparts. Upon stratifying by PD-L1 expression, the author observed that patients with DDR co-mutation who were also PD-L1 positive derived the greatest clinical benefit from ICI therapy. Upon analyzing the frequency of co-mutation within the DDR pathway, the authors found that patients with SL co-mutation in the CPF-CPF pathway experienced remarkable survival benefit from ICIs. Within this group, one of the most common co-mutation combinations was TP53-ATM, observed in approximately 45% of cases, which was associated with a better response to ICI therapy. Further analysis of immune cell infiltration revealed that patients with TP53-ATM co-mutation exhibited a distinct tumor immune microenvironment. As the authors stated, the study's main limitation lies in the nature of retrospective analysis, which lacked the control over confounding variables and was subject to non-random sampling. For instance, patients with both SL co-mutations and DDR SL co-mutations exhibited high TMB, and TMB was known to be associated with improved response to ICI therapy itself. So, these findings require validation through prospective studies, and immune infiltration analysis needs confirmation via laboratory experiments. In conclusion, the authors found that patients with SL co-mutations in DDR pathways showed favorable clinical response and prolonged survival following ICI therapy. They also identified TP53-ATM co-mutations as a clinically relevant biomarker for predicting ICI treatment response. Thank you for tuning in to JCO Precision Oncology Article Insights. Don't forget to subscribe and join us next time as we explore more groundbreaking research shaping the future of oncology. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.
On today's episode, Vince welcomes back Pierre Rausini to uncover how drug trafficking, money laundering, and geopolitics collide. They break down Venezuela's transformation into a trafficker's haven, the Cartel de Soles' shadow role within the Venezuelan state, and how synthetic opioids dominate the market. The conversation digs into the sophisticated financial networks that keep cartels alive, the U.S. government's efforts to disrupt them, and the global power plays that shape who profits and who falls. Borderland is an IRONCLAD Original Sponsors: visit: https://www.1stphorm.com/borderland Free shipping through this link on any orders over $100 Free 30 days in the app for new customers (offer comes via email after the purchase) 110% money back guarantee on all of our products. We believe fully in our products. If you don't love the product or you aren't getting the results you hoped for, let us know and we'll give you your money back … plus 10%! AmmoSquared Visit https://ammosquared.com/ today for a special offer and keep yourself fully stocked. With over 100,000 members and thousands of 5-star ratings, Your readiness is their mission. TacPack Visit http://www.TacPack.com and use code IRONCLAD at checkout to get a free $70 tactical gift Learn more about your ad choices. Visit megaphone.fm/adchoices
This man experienced the worst effects of his life...
Last week, in one of Karen's classes, a student was surprised to learn that some information she had received from ChatGPT was inaccurate. With AI becoming increasingly common in perfume making - from formulations to safety advice - this week, Karen is offering an overview of how AI fits into the world of fragrance, where it can be helpful, where it falls short, and how you can get the most out of this ever-evolving tool. KEY TAKEAWAYS How exactly do models like ChatGPT work? Where do they get their information from, and how do they differ from search engines? Karen explains it all. Any answer you get from ChatGPT sounds 100% correct and authoritative. As Karen explains, not only is there a reason for this, but it's also one of its major flaws. A lot of the big perfume houses have been very vocal recently about incorporating AI into their formulation process. However, as Karen points out, it's not in the same way that you might be using it. However, despite its flaws, AI can be a very useful tool in some areas. Karen lays out some of the ways in which AI can help you. BEST MOMENTS “ChatGPT doesn't evaluate credibility or cross-check sources to see what is accurate.” “It isn't just incorrect, it's wrong with confidence.” “If the AI models have been trained by mistakes on the internet, then you can start to understand where the mistakes are coming from.” VALUABLE RESOURCES Getting Started Guide Artisan Perfumery Mastermind ABOUT THE HOST Fragrance expert, author, teacher and speaker; Karen Gilbert runs courses in the UK and online which demystify the secretive world of perfumery in a fun and interactive way. Karen has inspired thousands of students to explore their olfactory sense and create their own personalised fragrances. With extensive product development experience in both the commercial perfumery and the organic skincare industry, Karen is able to offer a unique insight into creating natural and mixed media fragrances for fine fragrance, room scents and skincare/bodycare products using commercial perfumery techniques. Karen is also a certified meditation teacher and has a passion for helping people to create daily rituals that integrate scent with other modalities to shift state and increase your sense of wellbeing. CONTACT DETAILS Website Instagram Facebook YouTube Email This Podcast has been brought to you by Disruptive Media. https://disruptivemedia.co.uk/
Jon Herold and Chris Paul tackle a packed episode of Devolution Power Hour, opening with Trump's surprise “med bed” healthcare announcement and the AI-generated video that set the internet buzzing. They question the line between satire, soft disclosure, and information warfare, comparing it to Hollywood's visions of instant healing tech. From there, the hosts dive into synthetic reality, showing how AI videos and fabricated documents erode trust in evidence itself, reinforcing the need for skepticism in an information war. They explore Trump's new NSPM on domestic terrorism, its connection to 18 U.S.C. §§ 241–242, and how it may tie into the broader “RICO Grande” case against the Deep State. With sharp analysis of the Comey indictment, Kash Patel's pushback, John Brennan's televised denial, and the looming government shutdown, Herold and Paul connect today's chaos to larger strategies of exposure, leverage, and constitutional restoration. From Soros to January 6th optics, from the Pentagon's unprecedented Quantico gathering to the auto-pen saga, this episode lays out the converging narratives shaping America's next chapter.
In this episode, we confront the growing detachment from reality in today's culture. From AI-generated deception to the normalization of violence and evil on our screens, many are becoming numb to the weight of truth and morality. What happens when we lose touch with what’s real and what’s right? Join us as we explore how God's Word can soften hardened hearts, restore discernment, and ground us in a world that’s drifting further from truth. (00:00) Culture, Lawlessness, and the Synthetic Effect(14:38) Synthetic Reality and Moral DecayCONNECT WITH PASTOR JACK:Get Updates via Text: https://text.whisp.io/jack-hibbs-podcast Website: https://jackhibbs.com/Instagram: http://bit.ly/2FCyXpOFacebook: https://bit.ly/2WZBWV0YouTube: https://bit.ly/437xMHn CALLED TO TAKE A BOLD STAND:https://boldstand.org/DAZE OF DECEPTION:https://jackhibbs.com/daze-of-deception/ Did you know we have a Real Life Network? Sign up for free today for more exclusive content:https://www.reallifenetwork.com/
This week we have Kay back on to talk about AI and what the refusal of AI means in terms of library practice and theory. Bsky: @kslater.bsky.social Media mentioned Kay's article in Library Trends: Against AI: Critical Refusal in the Library The AI Con (book) https://thecon.ai/ “Synthetic literacy” forthcoming from Dr. Kishonna Gray https://www.kishonnagray.com/ librarians doing infolit session part of that is telling the students how it will track you - privacy issues https://www.inthelibrarywiththeleadpipe.org/2016/putting-critical-information-literacy-into-context-how-and-why-librarians-adopt-critical-practices-in-their-teaching/ https://infolit.org.uk/privacy-and-surveillance-in-the-classroom-responding-to-new-information-literacy-challenges/ https://acrlog.org/2020/11/13/privacy-consent-and-the-virtual-one-shot/ https://datalabelers.org/ https://www.fortinet.com/resources/cyberglossary/cia-triad The People's Platform (book) https://us.macmillan.com/books/9781250062598/thepeoplesplatform/ Transcript: https://paste.ofcode.org/HNKAPrHLSPgUpNuraN3m2F Join the Discord: https://discord.gg/zzEpV9QEAG
Dr. Carrie Jones isn’t just another voice in the hormone space... she’s been prescribing and teaching HRT for over 20 years, and it shows. In this episode we cover some epic ground when it comes to perimenopause and hormone replacement therapy with straight talk on what works, what doesn’t, and why so many women are being dismissed or mismanaged. We dig into the real differences between bioidentical vs synthetic hormones, why progesterone is usually the first to decline, how testosterone fits into women’s health, and the messy reality of managing symptoms when cycles start shifting all over the shop. Dr. Carrie shares the side effects to look out for, what doctors often get wrong, and why it’s okay (sometimes necessary) to 'cheat' on your GP. If you’ve ever wondered whether HRT is safe, whether you're too young, too old, when's the best time to start, or why you’re still feeling flat on it, this is the conversation you've been waiting for.SPONSORED BY TESTART FAMILY LAWYERS Website: testartfamilylawyers.com.au CARRIE JONES Website: drcarriejones.com TIFFANEE COOK Linktree: linktr.ee/rollwiththepunches/ Website: tiffcook.com LinkedIn: linkedin.com/in/tiffaneecook/ Facebook: facebook.com/rollwiththepunchespodcast/ Instagram: instagram.com/rollwiththepunches_podcast/ Instagram: instagram.com/tiffaneeandcoSee omnystudio.com/listener for privacy information.
Mark 2:27 NIV "Then he said to them, “The Sabbath was made for man, not man for the Sabbath." *DISCLAIMER* This episode contains adult themes and is not intended for little ears. *Transcription Below* Emily MacLeod-Wolfe is a Nurse Practitioner wellness professional with a passion for helping individuals achieve their health goals in a holistic and practical way. With 5 years of invaluable experience in the field, Emily has developed a deep understanding of the importance of a balanced lifestyle for a vibrant life. Emily firmly believes in treating the whole person, not just the symptoms, and takes a comprehensive approach to healthcare. She learned these from her own personal experience of dealing with Hashitmotos thyroiditis and eczema and found the root causes to treat them naturally. She is passionate to help others with the personal knowledge and health freedom she has received. By combining her medical expertise with a focus on nutrition, exercise, and mindfulness, she empowers her clients to take control of their health and make sustainable lifestyle changes. With a warm and empathetic demeanor, Emily creates a safe and supportive environment where clients feel heard and understood. She works closely with each individual to develop personalized wellness plans that are tailored to their unique needs and circumstances. Whether you're looking to improve your physical fitness, manage stress, or simply lead a healthier life, Emily is dedicated to guiding, encouraging & supporting you on your wellness journey. Emily's Website Questions and Topics We Cover: Will you give us an intro lesson for hormones 101? Is it normal to have really painful and heavy menstrual cycles or is that an indicator that something is not right? What are the best practices you recommend for women to support healthy hormones and healthy adrenals in their body all month long? Thank you to our sponsor: Leman Property Management Episode Mentioned Today: 256 Gut Health, Allergies, Inflammation and Proactive Solutions with Emily Macleod-Wolfe Other Related Episodes on The Savvy Sauce Podcast: 81. Sacred Rest with Doctor, Wife, Mother, and Author, Dr. Saundra Dalton-Smith 167. Pursuing Health in Four Key Areas with Debra Fileta 205. Power of Movement with Alisa Keeton (Revelation Wellness) Hormones and Simple Changes to Feel SO Much Better with Functional Medicine Expert, Dr. Jill Carnahan Practicing Sabbath with Shireen Eldridge Special Patreon Re-release: Out of the Box Stress Relievers to Apply Today with Dr. Saundra Dalton-Smith 215 Enriching Women's Sexual Function, Part One with Dr. Kris Christiansen 216 Enriching Women's Sexual Function, Part Two with Dr. Kris Christiansen 217 Tween/Teen Females: How to Navigate Changes during Puberty with Dr. Jennifer Degler Connect with us through The Savvy Sauce Website Gospel Scripture: (all NIV) Romans 3:23 “for all have sinned and fall short of the glory of God,” Romans 3:24 “and are justified freely by his grace through the redemption that came by Christ Jesus.” Romans 3:25 (a) “God presented him as a sacrifice of atonement, through faith in his blood.” Hebrews 9:22 (b) “without the shedding of blood there is no forgiveness.” Romans 5:8 “But God demonstrates his own love for us in this: While we were still sinners, Christ died for us.” Romans 5:11 “Not only is this so, but we also rejoice in God through our Lord Jesus Christ, through whom we have now received reconciliation.” John 3:16 “For God so loved the world that he gave his one and only Son, that whoever believes in him shall not perish but have eternal life.” Romans 10:9 “That if you confess with your mouth, “Jesus is Lord,” and believe in your heart that God raised him from the dead, you will be saved.” Luke 15:10 says “In the same way, I tell you, there is rejoicing in the presence of the angels of God over one sinner who repents.” Romans 8:1 “Therefore, there is now no condemnation for those who are in Christ Jesus” Ephesians 1:13–14 “And you also were included in Christ when you heard the word of truth, the gospel of your salvation. Having believed, you were marked in him with a seal, the promised Holy Spirit, who is a deposit guaranteeing our inheritance until the redemption of those who are God's possession- to the praise of his glory.” Ephesians 1:15–23 “For this reason, ever since I heard about your faith in the Lord Jesus and your love for all the saints, I have not stopped giving thanks for you, remembering you in my prayers. I keep asking that the God of our Lord Jesus Christ, the glorious Father, may give you the spirit of wisdom and revelation, so that you may know him better. I pray also that the eyes of your heart may be enlightened in order that you may know the hope to which he has called you, the riches of his glorious inheritance in the saints, and his incomparably great power for us who believe. That power is like the working of his mighty strength, which he exerted in Christ when he raised him from the dead and seated him at his right hand in the heavenly realms, far above all rule and authority, power and dominion, and every title that can be given, not only in the present age but also in the one to come. And God placed all things under his feet and appointed him to be head over everything for the church, which is his body, the fullness of him who fills everything in every way.” Ephesians 2:8–10 “For it is by grace you have been saved, through faith – and this not from yourselves, it is the gift of God – not by works, so that no one can boast. For we are God‘s workmanship, created in Christ Jesus to do good works, which God prepared in advance for us to do.“ Ephesians 2:13 “But now in Christ Jesus you who once were far away have been brought near through the blood of Christ.“ Philippians 1:6 “being confident of this, that he who began a good work in you will carry it on to completion until the day of Christ Jesus.” *Transcription* Music: (0:00 – 0:12) Laura Dugger: (0:12 - 1:29) Welcome to The Savvy Sauce, where we have practical chats for intentional living. I'm your host, Laura Dugger, and I'm so glad you're here. Today's message is not intended for little ears. We'll be discussing some adult themes, and I want you to be aware before you listen to this message. Leman Property Management Company has the apartment you will be able to call home, with over 1,700 apartment units available in central Illinois. Visit them today at lemanproperties.com, or connect with them on Facebook. Emily McLeod-Wolfe is my returning guest for today. Last time we talked about everything related to gut health, and I'll make sure to link that episode in the show notes for today's episode. I would highly recommend that you begin there, because there's a lot of overlap with solutions, as then we transition today into our topic about female hormones, the menstruation cycle, and how to make everything better, and even end up grateful to God for our female cycle. Here's our chat. Welcome back to The Savvy Sauce, Emily. Emily Macleod-Wolfe: (1:30 - 1:34) Thank you so much for having me again, Laura. I'm so excited about this section. Laura Dugger: (1:35 - 1:40) Yes, can you just give us a brief reminder of the work that you get to do before we dive in? Emily Macleod-Wolfe: (1:41 - 2:08) Yes. I am a holistic nurse practitioner. I was trained traditionally in traditional medicine at Vanderbilt, and then I went on to do ... Well, from my own personal health journey, I knew I wanted to do more holistic medicine, so I went on and did functional medicine, natural medicine training, so, now I have a practice called Pure Integrative Health, which is to blend the best of both worlds, and to basically to root cause medicine. Laura Dugger: (2:08 - 2:19) Well, and we covered all things gut health last time, but I've been so excited to interview you about hormones, so as best as you can, could you just give us Hormones 101? Emily Macleod-Wolfe: (2:21 - 3:02) Yeah, yeah. And first of all, if you didn't hear the last episode, I would recommend go back to listen to the previous one, because the gut health is the precursor that builds to the hormones, and I don't recommend even trying to address the hormones unless you've got some of the gut healing going, because they are so interconnected, even in the way in which we don't want to be recycling hormones, so constipation is causing an excess hormone recycling that should not be happening. So, again, healthy gut health is going to help the hormones, but yes. So, for women, or for men, or what hormones would you like me to describe? Laura Dugger: (3:02 - 3:11) I think we're just going to focus on women's hormones today, because I want to get more into our cycle as well. Emily Macleod-Wolfe: (3:11 - 10:59) Oh, great question. Yeah. Okay. So, for women, we have the sex hormones, estrogen, progesterone, testosterone, not nearly as high levels of testosterone as men, they can be highly driven off of it. If the testosterone is too high in women, then we look at things like PCOS, polycystic ovarian syndrome, excess androgen, so it could be like abnormal hair growth, extra oily skin, acne, those are some signs of like maybe high testosterone, but also could be from high cortisol, which is the stress hormone that's made in the adrenal glands that sits on top of the kidneys and produces stress hormone. Now we'll explain how the adrenals and the stress hormone cortisol affect some of the sex hormones, but those ones, and then there's one called DHEA, and that is the precursor hormone to testosterone. So, we've got estrogen, progesterone, testosterone, DHEA, pregnenolone is like the master hormone in which all the hormones can be made out of, and the cholesterol actually funnels into pregnenolone. So, our cholesterol is necessary, we do need good cholesterol to help all the hormones, so, yes, that's why good healthy fats and things like that are really helpful, like olive oil and avocado and baking, broiling and grilling things and all of that, the cholesterol, pregnenolone master hormone, we got DHEA, which is the precursor to testosterone. And then testosterone can be the hormone that converts into estrogen, so, they're all connected, they're all very connected, so excess estrogen could be from too high testosterone. Anyhow, they're all over the place sometimes for women, and they do fluctuate just even within 28 days, so I'll kind of explain that, and then we can kind of go from there. So, we talked about cortisol, there's a lot of other hormones, but I was just telling you about the sex hormones, so that's necessary to understand a cycle of a woman. So, when we start cycling, and then we have a couple different phases, we have the follicular phase, which is the first, day one is the day you start bleeding, and then day 14 is typically the day that we ovulate. So, day one, we have, estrogen starts to increase, we've kind of bottomed out, usually on our cycle, most women feel a little bit lower energy, I mean, we're bleeding and menstruating, and so some women lose a lot of iron, and ferritin levels can go down a lot during that, so we want to eat very iron-rich, lots of leafy greens, vegetables, good healthy fats to support. I kind of describe each week of our cycle, almost like a season, it's like winter is the first seven days of the bleeding, and then we've got spring, but then we start to feel really good, and everything is good, and then we've got summer, and we're doing great, and then we've got fall, and so we can kind of eat accordingly to, almost seasonally for the hormones, too. So, we've got the first seven days, lower energy, because estrogen and progesterone are pretty bottomed out, but they start to gradually increase. Now estrogen really starts to increase, and then right around day 14, it comes down, and then progesterone takes over, and so right there is the ovulation, and that's where the ovaries will release an egg, and has the opportunity to be fertilized or not in the middle of the month, and it all very much interconnects with our moods and how we're feeling, and people have heard of PMS, premenstrual syndrome, you felt the hormonal changes and all of that, but there's definitely ways that we can kind of mitigate the extreme highs and lows, like some people deal with depression-like feelings and really big mood swings, we can work on leveling those things more so that they're not so drastic through certain things I'll describe, but anyhow, we've got follicular phase, estrogen, we've got the luteal phase, we've got ovulation, then we've got the luteal phase is where progesterone is really increasing and decreasing, and that's days 14 to 28 of the cycle. So, we've got first phase and second phase. And two, we can break it down even more to four weeks. We've got like the first week, lower energy, but that's like, you can even connect it to emotions and how, like, maximizing efficiency for work based off of your cycle. Because even, you're not supposed to make a really big life decision during the menstruating week, because that's just low energy and all that. But it's a good time to dream, brainstorm, hopefully you're taking time to rest, take care of your body, have some salt baths, rich in magnesium, eating those good foods, giving nutrients, if your body needs, you get your iron levels checked and your ferritin levels. Your practitioner might give you an iron supplement that you're kind of taking in conjunction, depending on that. And so, we're resting and resetting and having time to journal, dream, and brainstorm things for the, you know, hopefully the next and then the next week, the estrogen is coming up a lot, and starting to feel back to normal self, usually really good and feeling that surge, the mood starts to get better, it's a great time to start to do like some good heavy weightlifting and exercise can even be based around cycle two. For menstruation, you're probably going to want to do a little bit more lower impact and walking and stretching, Pilates, things like that. And then a bar and all that and then weightlifting that second week is great. And then also, that's around ovulation is that's where we feel more loving and affectionate and different things and the way that God designed our body literally to want to be with a man around that time. And that's procreation time. And then right around the after ovulation, that third week, and fourth week can start to get challenging because that's where well, sometimes that third week is a good, sweet spot. But the fourth week, the week before the period. Yeah, like that day is 19 to 21. And then like after that, that's where some mood swings can start to happen. And the estrogens come down a lot progesterone depending on where the bodies at. Most women are deficient in progesterone overall. So, if it's already decreasing, it was a peak in the third week, and then it's decreasing, going towards menstruating again, then it's a recipe for not sleeping great mood swings, irritability, bloating, breast tenderness, that can be estrogen imbalances, excess estrogen, low progesterone like symptoms. And then yeah, that was a lot. Laura Dugger: (10:59 - 11:20) That's so helpful. I want right before we move on, because I want to hear how to mitigate some of those symptoms. But first, you mentioned eating seasonally, even each week. So, is that what you're saying that we eat more of those winter foods, that day one to seven? And could you give an example for each phase? Emily Macleod-Wolfe: (11:21 - 14:19) One example, Sweet potato, you know, like the foods that you would find more in the winter. So, you're kind of doing like sweet potatoes. And like I said, the fatty food, like a healthy fat Mediterranean, definitely right around the cycle. Body craves, if you find yourself craving chocolate, it's probably because your body's deficient in magnesium. Most of us are. So, some women will use it as an excuse to have chocolate, guilty as charged. But actually, it's magnesium deficiency, but chocolate has magnesium in it. So, if you get a rich, like dark chocolate, if you're not sensitive to chocolate, and you can do one that's a really dark and, and doesn't have a ton of sugar, then that could be a good source. But just foods rich in magnesium, dark leafy greens, avocados, nuts, and really checking levels and magnesium, Epsom salt baths, things like that, that's going to be great. You're going to want to do that also kind of the week before the period to in the fall like food. So, you know, like the, the squashes, and you kind of like the baked vegetables and, and protein and, and then like in the spring, like the week after, then maybe you're doing more like, you know, berries and, and, you know, things that you would have in this in the springtime and summer, different types of meat that you would like lean chicken and turkey. Then harvest like food for that week before the period to give you good. There's something called seed cycling. So, the pumpkin seeds and well, sesame and sunflower are for days 14 to 28 of the cycle. So, the second half that gives the body the micronutrients needed to help support progesterone and then pumpkin and wow, I'm really blanking probably because I need to eat lunch. But we can come back well it's going to come back to me the pumpkin and the is it chia? No, flax. Flax. Okay, flax seed. Pumpkin and flax for days one, the day we start bleeding to ovulation day 14, and then sesame and sunflower days 14 to 28. So, like adding those into smoothies, handful of nuts, nut butter, sunflower seed butter, you know, those kinds of things. Those that can also kind of support the cycle naturally and give the body the nutrients that are needed to support the body like that. Laura Dugger: (14:19 - 14:37) Okay. I have heard about seed cycling before. It kind of ties into the other question I had. I wondered if it's normal to have really painful and heavy menstrual cycles? Or is that an indicator that something's not right and maybe we need to bring in something like seed cycling? Emily Macleod-Wolfe: (14:39 - 18:15) Yes, painful, heavy menstruation. That's not normal. I personally have dealt with them. So, I understand they're awful and they can leave some women, you know, nauseous, throwing up, vomiting, breast tenderness. Now, that signs of excess estrogen that likely needs to be detoxed. And I would recommend going to a holistic practitioner and asking them to do a saliva hormone testing panel. Actually, we have no, I don't have it with me right now. But it's basically these vials of saliva that you spit right when you wake up, lunchtime, dinnertime, bedtime, and it'll check sex hormones between days 19 to 21 of the cycle. We're checking peak progesterone time so we can look at the most accurate depiction if you're cycling. It's still possible to do it if you're postmenopausal and want to do the test, we could do it at any time. But it's a saliva hormone test is the most accurate way to measure hormones and see exactly what's going on. We can check blood work, but it's just like a little shot in the dark. But the saliva is the more accurate picture of what's going on. So, I would recommend if you're having really heavy menstrual cycle, yes, you can try the seed cycling to start. That's harmless to try. But there might be more things going on that really need to be seen by a practitioner to help either support what hormone is low or detox another hormone that is excess. Now, we are overall in our society getting a lot of excess estrogen. And that can be through plastics, we get a lot like trying to switch even just a bottle as I'm drinking through. We don't want to try and drink as much plastic out of plastic, we want to do like glass water bottles. And like stainless steel water bottles better. Unless you're in a crazy rush and you forgot to bring one is better drink some water than no water. We've got to stay hydrated to have healthy bowel movements to have energy to our cells, all of that good water filter that filters out fluoride, chlorine, those things will affect the thyroid very much so. Thyroid hormones affect sex hormones and etc. So, we want to get a good filter for the water so that we don't have to deal with the after effects of thyroid imbalances or if you're already dealing with thyroid imbalances. I understand because I've dealt with that myself. And so, we want to remove as many stressors because the thyroid needs iodine just to function. And if we're getting fluoride and chlorine, those particular elements compete for iodine in the body. So, we got to get those out as best as we can get rid of excess estrogen. Through plastics, chemicals and detergents, like all of the chemicals that are exposed in detergents and cleaning products. As much as we can clean those up as well, it's going to be very, very helpful for thyroid, very helpful for sex hormones. Laura Dugger: (18:16 - 18:26) Oh, that's interesting. So, those I don't even think of that are like store brand names for detergents that those could be endocrine disruptors, you're saying? Emily Macleod-Wolfe: (18:26 - 18:45) That's great. Yes. So, endocrine disruptors are things that are going to cause imbalances to the thyroid, the sex hormones, or any of their other hormones in the body. Yes. So, we definitely want to try and stay away from those things. Laura Dugger: (18:46 - 21:10) Let's take a quick break to hear a message from our sponsor. With over 1,700 apartment units available throughout Pekin, Peoria, Peoria Heights, Morton, Washington, and Canton, and with every price range covered, you will have plenty of options when you rent through Leman Property Management Company. They have townhomes, duplexes, studios, and garden-style options located in many areas throughout Pekin. 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They're also hiring in their maintenance department, so we invite you to find out why so many people have chosen to make a career with them. Check them out on Facebook today or email their friendly staff at leasing at lemanprops.com. You can also stop by their website at lemanproperties.com. That's L-E-M-A-N properties dot com. Check them out and find your place to call home today. Okay, so I'm even thinking, so females my age or friends or older or younger women listening, even we have four daughters and so as they grow and mature, all of this is helpful. I'm assuming to start at a young age with getting rid of some of those toxins or not microwaving food on plastic plates, but then also you said detox. Is that through hydration or did you mean something else with detoxification? Emily Macleod-Wolfe: (21:11 - 22:47) I can't get into this unless I saw somebody as a patient because I can't give across the board recommendation for this, but I will say because there are certain supplements and things that might be needed. Say there's excess estrogen in the body, there might be supplements that that person needs to help bring down those excess estrogen levels aside from food. But one thing that I do know that you can eat that helps overall is the more that you love and detoxify the liver. It's what has to process all the hormones. One thing is broccoli sprouts, not broccoli, broccoli sprouts. So, you know, micro green sprouts, those ones, the broccoli sprouts are incredible at helping getting rid of the bad kinds of estrogen, detox those out of the body. So, that's really good. Cruciferous vegetables, cooking your cruciferous vegetables though, because if you eat them raw, it can affect the thyroid negatively. So, it's best to, it could cause goiters and so we don't want that. It can be goitrogenic essentially. So, we don't want that, but you could bake. I mean, you could cook cruciferous vegetables, broccoli, brussels sprouts, kale, etc., those cruciferous vegetables, spinach, all that. And those are great also for that. So, that can help. The best one is the broccoli sprouts. Yes. And then getting saliva hormone testing done and seeing exactly where your body is at. Laura Dugger: (22:48 - 22:53) Okay. Cause I'm wondering then could that even be a mineral deficiency when you're talking about supplements? Emily Macleod-Wolfe: (22:55 - 27:11) Yeah, there definitely can be mineral deficiencies. It just, like I said, I've seen a lot of different variations, right? Excess estrogen, low progesterone, low menopausal, low everything. Once the hormones bottom out, then they're kind of low across the board and the body might need bioidentical hormones to have extra support. It's cardioprotective, protective against cancers, protective for the bones, different things like that. Bioidentical is different than synthetic. Synthetic hormones is like birth control, but synthetic hormones can, go see the last episode when we talk about leaky gut intestinal permeability, but the birth control can actually cause intestinal permeability too. So, that's a problem. Leaky gut can be from birth control, the synthetic birth control, and then the body's not even able to ovulate. It's not able to release. There's just like the, the way that God designed it is we're actually, if you allow it to look at it as like a cleansing and a purging every month, that spiritually the Lord, if we allow the Lord, we don't have to dread it. It's so common in society to dread a period. Or, oh my gosh, again, here we go. But how beautiful it's a celebration of the ability to give life. It's an opportunity to take some time to rest. It's a beautiful time to take some time to sit back and reflect, especially that week before the period. Also try and not make big decisions the week before because the progesterone's bottomed out causing mood swings and then making decisions is going to be a lot more stressful and can lighten load and work a little bit that week before, a few days prior to your period. That would be very helpful. Stress levels really impact the cycle and also just trying to prepare the body for going through perimenopause and then menopause. Wherever you're at in your health journey, life journey, it's, it's just so good to educate younger women to be really taking care of their adrenals, which is this, you know, the organ that produces stress hormone because high cortisol, which is the stress hormone produced by the adrenal glands, zaps progesterone and most women, that's probably why I see a lot of progesterone dipping so quickly. You need progesterone to have a healthy pregnancy. So, we're seeing a lot more miscarriages and infertility problems could be from low progesterone. And, um, and then that will eventually bottom out with menopause because the ovaries are not producing it anymore. And the only place that we have progesterone left in reserves is in the adrenal glands. And so, if the stress has been going on for so long, then even the reserves of the backups of the backups are gone, the progesterone, which is why I see a lot of women going through a more extreme version of menopause than with the night sweats and the hot flashes and all those things that maybe didn't even have to happen. Because, uh, if we take care of it on, on the earlier end of managing stress levels, going to bed at good times, getting full amount of sleep, women need eight to 10 hours of sleep. We will, I will just go ahead and say that because our hormones are very independent, dependent on our adrenal function. Men, they don't really have to rely on their adrenals as much as their other, other sex hormones and locations. Um, so they don't have to deal with it as much as the women. So, we're constantly tied to a function of our adrenals really affects our sex hormones like crazy. And we're not getting the right amount of sleep. Then we're going to have high stress levels, high cortisol, and then the high cortisol is where it is at the sex hormones. So, we need those reserves to be replenished and the, and the cortisol levels drop and melatonin kicks in and we're going to sleep so much better and sleep so much deeper. Laura Dugger: (27:12 - 27:36) Wow. This is fascinating. And I love how you're even celebrating the cycle and how God created it because I'm forgetting one of them, but I heard that menstrual blood was tested, and they saw that it was detoxifying plastics and pesticides. And there was one other thing that the body was using to eliminate. And so that's a reminder just to be grateful for that too. Emily Macleod-Wolfe: (27:36 - 29:08) And, uh, the birth control pill, it's a temporary fix. There are alternative forms of birth control that do not have the synthetic hormones that are good, good options, you know, and the synthetic hormones though, I've firsthand seen it with patients negatively impact the thyroid. And a lot of them have had to end up on thyroid medication just simply due to years and years of birth control and it impacting the thyroid and the cellular health as well as the lining of the gut and a lot of other side effects that I'm not a weight gain, different things. And then the body not even being able to menstruate and fully excrete things. And, um, or even, you know, the, the cycle is an indicator, I think for women very much of like your monthly health, like how, how am I doing? Like if I'm having a really bad period, um, likely it was something that I had done this past month. Okay. Did I eat right? Was I sleeping? Was I incredibly stressed? Usually, you can trace it back to that. Now there's obviously other cases where, you know, PCOS and ruptured ovaries and different things like that, or ruptured cysts on the ovaries, sorry. Um, then that can contribute to longer term diseases, but on a, it's almost like a litmus test to see how, how our bodies are doing. Laura Dugger: (29:09 - 29:27) I like that perspective. And Emily, you're so great at giving proactive tips and I love easy wins. So, what are some of the best practices that you recommend for women to support healthy hormones and healthy adrenals in our bodies all month long? Emily Macleod-Wolfe: (29:30 - 33:32) One is glucose management. So, protein, I cannot emphasize it enough protein sources, um, you know, good, healthy, as much as you can, grass fed organic meat. So, you're not getting the synthetic hormones from them because who knows what they're being fed and what they're being pumped with, but those sources, um, protein, other sources of protein, um, that's going to give you up to 15 hours of energy. So, that is incredible. As far as eating for energy, I will say, if you can do that, that's, um, it's incredible. It's a game changer, eating for energy, protein, vegetables give us up to five to six hours of energy. And then carbs, carbs give us, um, like if we had a piece of fruit, it only lasts in the system for 15 minutes. Or, um, potato chips, something like that, 15 minutes, that's not very long. And then the body says, ”I'm hungry again.” Then we ended up overeating because we just had the carbs and we're not full. And so, that's why pairing the meals around the protein and then the fiber and then a healthy fat. Or like the protein, the fiber and a complex carb (sweet potato, brown rice, quinoa). Things like that is going to stabilize the blood sugar. So, there will not be cortisol stress levels spiked when we don't eat for too long, then it can cause the body to go into, um, stress overload. And there's four different stages of adrenal fatigue, cortisol, and that can affect the body very much. So, spikes and crashes in glucose spike and crash the cortisol and then spikes and cortisol will steal your progesterone and then cause imbalances because progesterone keeps the estrogen in check. So, then you got estrogen and progesterone imbalances. Then there's DHEA, which is the other hormone that's made in the adrenals. So, sometimes DHEA, DHEA is incredible for building muscle, keeping muscle concentration, memory. It's, wonderful at libido, all sorts of those things. Now, DHEA just decreases as we age. It's the precursor to testosterone as well, but it's also made in the adrenal glands. And so, the more we can regulate cortisol and adrenal, sometimes high levels of stress, we've got to go back and think. Okay, um, we might not even feel stress, but if there's been physical abuse, emotional abuse, or sexual trauma, those are serious things that the body will hold on to. And unless you have gone to process, I recommend getting a Christian counselor and process those things because the body can literally still be holding onto it 20, 30, even 40 years, if it's not been let go and given to Jesus. And, um, so that is also a huge, we can't dismiss that or just try and fix the physical. If there's been some stressors and the body has just been in survival mode and has to just keep going, then maybe it only knows how to live off of high cortisol stress reserves to just keep going. It doesn't, but if you have a hard time falling asleep, a hard time unwinding, feel like you're always on the go, those are like adrenal stages one and two high cortisol, but then that eventually will start to plummet. And then it's, um, you know, more difficult time getting out of bed and jumping straight out crash in the afternoon with energy crash after dinner crash before bed, um, or like wired and tired, like wired the brain's wired. The body feels tired, but can't go to sleep. Then further stages waking up between 2:00 and 4:00 in the morning could be blood sugar, adrenal issues as well. Laura Dugger: (33:32 - 33:41) Oh, could you speak a little bit more into that? Could be, the blood sugar related to the adrenal issues if you're waking up at that 2:00 to 4:00 AM time? Emily Macleod-Wolfe: (33:42 - 34:47) Yes, it can be, the body signaling that the blood sugars drop too low. And then the cortisol has to, it can signal to the cortisol and the adrenals to spike to just keep the body going, survive. And then all of a sudden cortisol is spiking at night, which it should not, it should be done. And melatonin should be happening at night and then cortisol in the daytime. So, if there's a cortisol spike because of a glucose crash, then, um, then we need to support it with, a spoonful of almond butter before bed, a handful of nuts, something, some protein before bed is going to, help someone, you know, in the middle of the night, stabilize the blood sugar. It can be a blood sugar issue with, cause blood sugar and cortisol are interconnected, but also should just check your cortisol levels, get a saliva test. It's that saliva four point, um, test checks for sex hormones and cortisol, or we can. Laura Dugger: (34:47 - 35:06) So. Okay. One more thing with that. So, then the blood sugar dropping that low, is that somebody who's maybe completing their closing, their eating window too early in the day, or they're not getting enough sugar throughout the day. Is that what you're saying with, why would it drop to that level and require cortisol? Emily Macleod-Wolfe: (35:08 - 36:51) Great question. It would be, it could be the person's not eating enough throughout the day and the body just doesn't have the right. So, if the person was fasting quite frequently and doing that a lot now, everybody, everyone's body is different. If you have adrenal imbalances, I do not recommend doing fasting because the body is already under stress and then fasting can put extra stress on the body. So then you're like, well, but then they said that if I fast and I should lose weight, and if you're fasting and you're gaining belly fat and you're gaining weight, it's a telltale sign cortisol because high cortisol level, puffy face, um, belly fat, stubborn, you can eat right exercise, try and do everything and it will not leave. That's usually survival mode. Body's trying to self-protect. Um, and so, yeah, so we don't want to be fasting very much if there's cortisol imbalances. Now, if there's not, and if you have your cortisol check, then there's great benefits to doing intermittent fasting and things. And even biblically spiritually, there's incredible benefits to fasting. The Lord knows there's the cells literally repair themselves, regenerate and can eat up cancer cells. If we put our bodies into that ketosis state for good bit, but that is not something I would recommend doing high intensity exercise, or that's going to put a lot of cortisol stress on the body, high impact, um, or skipping a lot of meals. So, that could be why the blood sugar is like dropping in the middle of the night. Laura Dugger: (36:52 - 37:37) I just wanted to let you know, there are now multiple ways to give when you visit TheSavvySauce.com. We now have a donation button on our website and you can find it under the donate page, which is under the tab entitled support. Our mailing address is also provided. If you would prefer to save us the processing fee and send a check that is tax deductible. Either way, you'll be supporting the work of Savvy Sauce Charities and helping us continue to reach the nations with the good news of Jesus Christ. Make sure you visit TheSavvySauce.com today. Thanks for your support. Is there anything else that we haven't gotten to discuss yet that you want to make sure we don't miss out on? Emily Macleod-Wolfe: (37:38 - 39:15) So what, when do you know if you're in perimenopause versus menopause? And like I said, if you're a woman in your twenties and you're like, that does not apply to me. Actually, it does because it's just, you don't want to get to menopause and have no reserves. Progesterone left because you depleted it from high levels of cortisol over the years. So, lifestyle changes, the protein, smaller, more frequent meals, the consistent bedtime, trying to go to bed before midnight, like 10:00 PM is like a sweet spot. 10:00 PM to 2:00 AM is when the liver detoxes, when cholesterol gets flushed, all these different things. Melatonin window for the body to like fall asleep and stay asleep is between 10 PM and like, there's sometimes it's even earlier. It just depends on the person. And I actually use a little app called Rise. It does a good job kind of helping you track where you're melatonin and when you're awake window, when to cut off eating and when to kind of wear blue light blocking glasses to prevent your body to blue light helps. We set this in the last one, but blue light actually tells your body to stay awake. So, you don't want to be on your screens too late at night, or your body's going to be sending the signals to stay awake when you're trying to wind down. So, using softer lighting, doing candle lit, doing, you know, just mimicking outside when the sun goes down, we should be going down, going down to bed and sleep when the sun wakes up. That's when we should be getting up as well. Laura Dugger: (39:15 - 39:38) So, and getting that morning sunlight that we talked about. So important. And I forgot one quick follow-up question. When you talked about cortisol, too high of cortisol contributing to belly fat, that stubborn or puffy face, what would the solution be? Is it just manage your stress better or what's the takeaway there? Emily Macleod-Wolfe: (39:38 - 42:39) The takeaway is yes, there's things you can do glucose wise, blood sugar and food that we've talked about. Lifestyle wise, of course. I mean, a ton of it is we're American society that trophies busyness. And like the Bible literally talks about the importance of rest and the Sabbath and like even humans, we were made on day six, but the first day we were actually doing things, Adam and Eve was day seven, was the day of rest. My dad's a pastor and he actually just gave a sermon on rest and the Sabbath just last week at Harvest Sound. But it was just all about that we were created out of rest. Like we're there to start doing things out of that place of rest. And we just don't take that time. I mean, it's like, okay, we got to go, go, go, got to take care of the kids, got to go do this, go do this. How are you doing? Oh, I'm so busy. How about you? Like, it's almost like a trophy thing to say that, but really like, how about prioritizing that time? And it's so easy, especially as women and mothers to just say, oh, but I just want to take care of everybody else. But like, if you were to have a date with your friend, you wouldn't go overbook it with something else. You would prioritize that. Are you going to go do something for your child? You're going to prioritize that. So, I need you to also take time to prioritize your me time, prioritize the time. It's not selfish. It's necessary because you're going to be a better wife. You're going to be a better mom. You're going to be a better friend. If you take care of the needs, whether that's taking an Epsom salt bath once a week, and that's spending time mourning sunlight or writing a list of gratitude, doing things, write a list of things that bring you joy and just pick two or three of those a day. Like build that in - life's too short. Literally cortisol will kill you. Also, we didn't talk about that, but it's taking minutes off your life. So, life's too short to have cortisol, unnecessary cortisol spikes. So, as much as we can, it's prioritizing that learning the healthy boundaries saying no when needed to, and, not saying yes to everything. So, that is, it's a lot of those lifestyle things. And then, fine tuning it with a health practitioner is great because everybody's spikes and crashes are in different places. Some people have high cortisol. Some people further on into the adrenal fatigue have low cortisol because the body doesn't have any more cortisol to give. And that's a whole other list of symptoms of exhaustion and fatigue. And they might need actually glandular support and different, totally different supplements than someone that's got high cortisol, but they can present similarly as far as stubborn weight, puffiness, energy spikes and crashes and different things like that. Laura Dugger: (42:40 - 43:04) So how incredible to get to follow up with a health professional then, and you are certainly one that we would recommend. And so even if we're out of state, but we could make a first appointment with you and figure out some way to do telehealth, can you just give us your website or share what you have to offer so that we can maybe make a follow-up appointment after this conversation? Emily Macleod-Wolfe: (43:05 - 43:38) So it's pureintegrativehealth.com. And I could click on the tab, become a patient, just fill that form out. And then we can talk about a plan if you're in Tennessee, great. We can just right away, we know you're in person. If you are out of state, I have to see you in person for the first initial eval and then we can come up with some hybrid plan of telemedicine in between visits and legally just need to be able to see you still once a year or something in person, but we could do the rest in telemedicine options. Laura Dugger: (43:39 - 43:58) So yeah, it's a wonderful option. We will link to that in the show notes for today's episode. And Emily, you're already familiar that we're called The Savvy Sauce because savvy is synonymous with practical knowledge or insight. And so as my final question for you today, what is your Savvy Sauce? Emily Macleod-Wolfe: (43:59 - 46:04) Well, in regards to this topic today with hormones, I would say my Savvy Sauce is actually, it would be around getting that bedtime routine down packed in order to have an eight to 10 hours of like actual sleep because the mind does a brain sweep and gets rid of toxins in the brain between seven and a half hours and nine hours. It's happened somewhere in that window. And so if we're skipping out on sleep, we're missing out. If you're getting even six hours, you're missing out on the neural brain sweep that actually gets rid of the toxins that prevent Alzheimer's, dementia, a lot of other problems. The metabolism at nighttime, the body literally burns fat at night. We have to get sleeping. And so, and if you're having problems sleeping, you're like, I want to sleep, but I haven't, then I would recommend start looking into different forms of magnesium. I can't get into it fully today because there's seven different kinds of magnesium, but there are some that will actually help with sleep. And so talk with your practitioner about the best forms that could help you increase your sleep as well, because most of us can be deficient in that and creating that really, really healthy rhythm. Just knowing your why behind why you're sleeping is also really helpful because it's like, you can hear a lot of people say, you need to get more sleep. I should go to bed, do this, but why? It's actually getting a neural sweep, liver is detoxing, cholesterol is cleansing. God does an incredible thing with our dreams. We're literally flushing and processing all the things from the day. And so, talk about stress and adrenals. We got to help heal through our sleep. Laura Dugger: (46:05 - 46:26) Wow. Thank you for leaving us with that word. There's so much more we could cover. And ever since our first interaction, you have just been overflowing with kindness and graciousness and generosity with your time and sharing your knowledge. You're so kind, but I have just loved spending this time with you. Thank you so much, Emily, for being my repeat guest. Emily Macleod-Wolfe: (46:27 - 46:32) Oh, my goodness. Thank you so much, Laura, for having me again. This has been wonderful. I really appreciate it. Laura Dugger: (46:33 – 50:15) One more thing before you go. Have you heard the term gospel before? It simply means good news. And I want to share the best news with you. But it starts with the bad news. Every single one of us were born sinners, but Christ desires to rescue us from our sin, which is something we cannot do for ourselves. This means there is absolutely no chance we can make it to heaven on our own. So, for you and for me, it means we deserve death, and we can never pay back the sacrifice we owe to be saved. We need a savior. But God loved us so much, he made a way for his only son to willingly die in our place as the perfect substitute. This gives us hope of life forever in right relationship with him. That is good news. Jesus lived the perfect life we could never live and died in our place for our sin. This was God's plan to make a way to reconcile with us so that God can look at us and see Jesus. We can be covered and justified through the work Jesus finished if we choose to receive what He has done for us. Romans 10:9 says, “That if you confess with your mouth Jesus is Lord and believe in your heart that God raised him from the dead, you will be saved.” So, would you pray with me now? Heavenly Father, thank you for sending Jesus to take our place. I pray someone today right now is touched and chooses to turn their life over to you. Will you clearly guide them and help them take their next step in faith to declare you as Lord of their life? We trust you to work and change lives now for eternity. In Jesus' name we pray. Amen. If you prayed that prayer, you are declaring him for me, so me for him. You get the opportunity to live your life for him. And at this podcast, we're called The Savvy Sauce for a reason. We want to give you practical tools to implement the knowledge you have learned. So, you ready to get started? First, tell someone. Say it out loud. Get a Bible. The first day I made this decision, my parents took me to Barnes & Noble and let me choose my own Bible. I selected the Quest NIV Bible, and I love it. You can start by reading the book of John. Also, get connected locally, which just means tell someone who's a part of a church in your community that you made a decision to follow Christ. I'm assuming they will be thrilled to talk with you about further steps, such as going to church and getting connected to other believers to encourage you. We want to celebrate with you too, so feel free to leave a comment for us here if you did make a decision to follow Christ. We also have show notes including where you can read scripture that describes this process. And finally, be encouraged. Luke 15:10 says, “In the same way I tell you, there is rejoicing in the presence of the angels of God over one sinner who repents.” The heavens are praising with you for your decision today. And if you've already received this good news, I pray you have someone to share it with. You are loved and I look forward to meeting you here next time.
Karen often hears from people who work exclusively with natural materials in their fragrances but are beginning to notice the limitations, whether it's their blends smelling too much like aromatherapy products or lacking longevity. If you want to move past these challenges and create fragrances that compare to commercial ones, the key is to incorporate synthetics. In this episode, Karen will share her recommendations for ten synthetic materials to add to your toolkit that will elevate your perfume creations to the next level. KEY TAKEAWAYS Hedione is a synthetic material that closely resembles jasmine, but smells lighter. Karen gives you an overview of this material, which is impossible to overdose, and changed perfume history forever. Musks are one of the biggest gaps when you're only working with naturals and it is synthetic musks that give perfume longevity. There are so many synthetic musks that can solve this problem. Karen shares her recommendations for the best synthetic musks to use. The ‘Heart of the Floral' is a fragrance made up from a trio of materials, and one of them, muguet, is only available as a synthetic. However, there are a few variations. Karen breaks down the differences between them. Sandalwood is a widely used material in perfumery, but if you want it to go all the way from the base to the top, you will have to rely on synthetics. Karen explains why and gives her recommendations for materials. BEST MOMENTS “Unless you start using synthetics, you're not going to learn how they work.” “Synthetics don't replace naturals, they enhance them.” “There are so many synthetic materials out there that it can be overwhelming to explore them for the first time. But, with the right approach, understanding them can add a new dimension to your perfume making.” VALUABLE RESOURCES Perfume Making 101 Studio Classes Episodes on materials Getting Started Guide Artisan Perfumery Mastermind ABOUT THE HOST Fragrance expert, author, teacher and speaker; Karen Gilbert runs courses in the UK and online which demystify the secretive world of perfumery in a fun and interactive way. Karen has inspired thousands of students to explore their olfactory sense and create their own personalised fragrances. With extensive product development experience in both the commercial perfumery and the organic skincare industry, Karen is able to offer a unique insight into creating natural and mixed media fragrances for fine fragrance, room scents and skincare/bodycare products using commercial perfumery techniques. Karen is also a certified meditation teacher and has a passion for helping people to create daily rituals that integrate scent with other modalities to shift state and increase your sense of wellbeing. CONTACT DETAILS Website Instagram Facebook YouTube Email This Podcast has been brought to you by Disruptive Media. https://disruptivemedia.co.uk/
Andrei from Falcon Finance and DWF Labs joins Sam to share how Falcon Finance is building universal collateralization infrastructure—where users can deposit crypto blue chips like BTC, ETH, SOL, stablecoins, and select altcoins, or tokenized U.S. Treasuries to mint USDf, a synthetic dollar that can be staked to generate sustainable yield.He explains how Falcon combines basis trading, arbitrage, and cross-asset liquidity to power competitive yield, why it's different from fiat-backed models, and how it plans to expand into tokenized stocks, bonds, and multi-chain collateral. We also cover risk management, transparency, regulation challenges, and advice for founders navigating Web3's evolving landscape.Key Timestamps[00:00:00] Introduction: Sam introduces Andrei from DWF Labs & Falcon Finance. [00:02:00] Crypto Beginnings: Ethereum mining, early Huobi experience, DWF Labs launch. [00:04:00] Falcon Finance Origins: Need for sustainable yield & collateralization platform. [00:06:00] How It Works: Deposit assets, set liquidation & sale prices, mint synthetic dollars. [00:08:00] Yield Sources: Basis trading, arbitrage, volatility trading, token staking. [00:10:00] Universal Collateralization: From BTC to tokenized stocks & bonds. [00:12:00] Synthetic Dollar Explained: Risk-managed, asset-backed liquidity representation. [00:15:00] USDf Reserves: ~$1.6B backed by BTC, stables, blue chips, altcoins. [00:17:00] Stablecoin Evolution: More collateral types & use cases emerging. [00:19:00] USDf Utility: DeFi strategies, transfers, future fiat off-ramps. [00:21:00] Growth Factors: Teamwork, transparency, market-driven product updates. [00:23:00] Roadmap: Tokenized RWAs, fiat channels, audits, decentralized governance. [00:25:00] Founder Advice: Focus on clients, timing, and market readiness. [00:27:00] The Ask: Partnerships for USDf adoption & collateral expansion.Connecthttps://falcon.finance/https://x.com/falconstablehttps://www.linkedin.com/company/falconstable/https://x.com/ag_dwfhttps://www.linkedin.com/in/andrewg77/DisclaimerNothing mentioned in this podcast is investment advice and please do your own research. Finally, it would mean a lot if you can leave a review of this podcast on Apple Podcasts or Spotify and share this podcast with a friend.Be a guest on the podcast or contact us - https://www.web3pod.xyz/
When your AI has to make decisions in the real world, the data you don't have can hurt people. DiffuseDrive CEO Balint Pasztor joins IT Visionaries to unpack the $124B data scarcity problem holding back autonomous systems — and how synthetic data (done right) can compress years of data collection into hours. We dig into: why edge cases matter (and how to safely create them), closing the sim-to-real gap with diffusion models, preventing model drift, and building a data engine for physical AI across defense, robotics, and industrial automation. If you care about self-driving cars, drones, QA on the factory floor—or just shipping AI that survives the messiness of reality—this one's for you. Key Moments: 00:00 Introduction to Autonomous Driving Challenges00:26 Meet Balint Pasztor and Diffuse Drive01:14 The Importance of Synthetic Data06:39 The Role of Synthetic Data in AI Training18:07 Understanding Diffusion Models23:28 Challenges in Real-World Data Collection26:46 Three Steps to Improve AI Performance32:13 Overcoming Non-Obvious Data Challenges36:00 Balancing Data Quantity and Quality40:28 Future of Autonomous Systems and Physical AI -- This episode of IT Visionaries is brought to you by Meter - the company building better networks. Businesses today are frustrated with outdated providers, rigid pricing, and fragmented tools. Meter changes that with a single integrated solution that covers everything wired, wireless, and even cellular networking. They design the hardware, write the firmware, build the software, and manage it all so your team doesn't have to. That means you get fast, secure, and scalable connectivity without the complexity of juggling multiple providers. Thanks to meter for sponsoring. Go to meter.com/itv to book a demo.---Mission.org is a media studio producing content alongside world-class clients. Learn more at mission.org Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Most people who buy life insurance never read the fine print. They're promised “stock market–like returns without the risk,” a retirement account that doubles as a tax-free loan machine, and peace of mind for their families. On paper? It looks like the perfect product. But what happens when the math doesn't add up, the illustrations don't match reality, and families find out, years later, that the policy they've been funding is set to collapse? That's the dark underbelly of the Indexed Universal Life (IUL) industry. And it's exactly what my guest, Jonathan, aka the IUL Exposer, has dedicated his career to uncovering. He's reviewed over 4,000 policies in just 18 months, uncovered systemic mis-selling, and even built a process that has helped families claw back over a million dollars in refunds. Jonathan isn't anti-insurance. He's anti–false promises. His work shines a light on how commissions drive product design, why regulators are warning against IULs, and how clients are left holding the bag when agents disappear. This episode isn't about theory, it's about hard numbers, legal battles, and the uncomfortable truths most of the industry hopes you never learn. Things You'll Learn In This Episode -Illustrations are a trap IUL projects steady growth that rarely happens. Why do clients still trust the numbers? -Commissions drive the product IULs are sold 10-to-1 over whole life because they pay the fattest commissions. What does that reveal about whose interests are really being served? -Refunds are possible Families often think their money is gone forever. How are some clawing back tens of thousands in refunds? -Indexes aren't what they seem Synthetic “uncapped” indexes promise market-like returns but rarely deliver. How are clients set up for disappointment from day one? Guest Bio Jonathan Aguilera is the voice behind @lifeinsurancerefunds on TikTok and Instagram, a platform dedicated to exposing misleading life insurance practices, breaking down complex policies, and helping families recover money they thought was lost. Licensed since 2012, Jonathan once built a national agency of 250+ licensed agents with Primerica. But when faced with the choice to “stay quiet to stay compliant” or speak up for what's right, he chose the latter. He resigned, surrendered his securities licenses, and walked away from everything he'd built to launch DTRT Financial, not just a company, but a movement. Jonathan isn't the suit-and-tie advisor chasing commissions. He's the guy who got fed up watching families get misled, overcharged, and under-informed. Through thousands of policy reviews, he's exposed the harsh realities of cash value life insurance while educating the masses on how to make intentional financial choices. Visit IULExposer.com to learn more. About Your Host From pro-snowboarder to money mogul, Chris Naugle has dedicated his life to being America's #1 Money Mentor. With a core belief that success is built not by the resources you have, but by how resourceful you can be. Chris has built and owned 19 companies, with his businesses being featured in Forbes, ABC, House Hunters, and his very own HGTV pilot in 2018. He is currently the founder of The Money School™, and Money Mentor for The Money Multiplier. His success also includes managing tens of millions of dollars in assets in the financial services and advisory industry and in real estate transactions. As an innovator and visionary in wealth-building and real estate, he empowers entrepreneurs, business owners, and real estate investors with the knowledge of how money works. Chris is also a nationally recognized speaker, author, and podcast host. He has spoken to and taught over ten thousand Americans, delivering the financial knowledge that fuels lasting freedom. Check out this episode on our website, Apple Podcasts, or Spotify, and don't forget to leave a review if you like what you heard. Your review feeds the algorithm so our show reaches more people. Thank you!
Join Holman and listener favorite Mike Rice, as the guys take a '24 Toyota Tacoma SR5 and add capability and looks on a budget. Will it be a TRD for the “poors” or did they blow the budget? Find out the answer to this and more, including all about Bilstein's new direct-replacement monotube Tacoma shocks. The guys also dig into AEV's GM HD truck packages. The Truck Show Podcast is produced in partnership with AMSOIL, Kershaw Knives, and OVR Mag.