Podcasts about aging research unit

In this episode of BrainStorm host Meryl Comer continues her compelling interview with "Rockstar of Science" Dr. Rudy Tanzi, the pioneering Director of the Genetics and Aging Research Unit and Director of the McCance Center for Brain Health at Mass General Hospital. Dr. Tanzi unveils the secrets of brain health and Alzheimer's research. Exploring his innovative SHIELD framework, Dr. Tanzi offers practical strategies for cognitive wellness, from sleep and stress management to diet and lifelong learning.The episode takes an innovative turn with AI-generated questions that probe the challenges of Alzheimer's research. Dr. Tanzi provides candid insights into prevention, early intervention, and the future of medical science, sharing an unexpectedly optimistic view of combating cognitive decline. Blending scientific expertise with actionable advice, this episode is a must-listen for anyone interested in brain health, aging, and medical innovation.Support the show

Today we have Dr. Rudolph E. Tanzi, who is perhaps best known for co-discovering all three familial early-onset Alzheimer's disease genes. In addition, Rudy's lab was the first to use human stem cells to create three-dimensional human brain organoids and three-dimensional neural-glial culture models of Alzheimer's disease, which became known as “Alzheimer's-in-a-Dish.” These models were the first to recapitulate all three of the key pathological hallmarks of Alzheimer's disease and have made drug screenings faster and cheaper. Rudy is the director of the Genetics and Aging Research Unit as well as the director of the Henry and Allison McCance Center for Brain Health. Rudy is also co-Director of the Massachusetts General Institute for Neurodegenerative Disease at Massachusetts General Hospital and serves as the Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard Medical School. Rudy has published more than 700 research papers and is one of the top 50 most cited neuroscientists in the world. He is author of “Decoding Darkness,” and a co-author of two books with Deepak Chopra, “Super Brain” and “The Healing Self.” Show notes: [00:03:18] Ken opens the interview mentioning that Rudy began playing the accordion when he was just seven years old. Ken goes on to ask Rudy about the time his father gave him a Jimmy Smith album and some advice. [00:05:51] Ken mentions that, in addition to Rudy's musical talents, he was also interested in science growing up. Ken asks about Rudy's participation in the Westinghouse Science Talent Search and what that experience was like. [00:07:09] Ken asks Rudy about growing up in Cranston, Road Island. [00:08:39] Rudy talks about how he ended up at the University of Rochester after high school. [00:09:51] Ken mentions that both Rudy's grandfather and father passed away at the age of 45. Ken asks Rudy if this played a role in his pursuit of a career in genetics research. [00:10:57] Rudy explains how he chose Harvard Medical School for his Ph.D. [00:12:47] Ken pivots to ask Rudy about his time working with Jim Gusella in the early 80's at Mass General, where they were the first to ever find a disease gene. Family studies at the time had shown that the Huntington's disease gene was linked to a polymorphic DNA marker. Rudy talks about this discovery and how the chromosomal localization of the Huntington's disease gene was the first step in using recombinant DNA technology to identify the primary genetic defect in this disorder. [00:16:07] Ken asks Rudy about his work in 1987, when he discovered the first Alzheimer's gene, recombinant DNA technology, which causes the production of amyloid. Ken goes on to explain that mutations in the APP gene can cause a rare form of early onset Alzheimer's. Rudy talks about the paper that came out in “Science” that detailed this discovery. [00:18:38] Rudy discusses his personal philosophy and approach to research. [00:19:43] Ken mentions that in Rudy's book, Decoding Darkness, he writes that few nightmares on Earth can compare to Alzheimer's disease. Ken asks Rudy to talk more about this book. [00:21:50] Ken explains that in the same way our physical capabilities will suffer some form of decline with age, it is also expected that we have some decline in memory and cognitive ability as we age as well. However, Ken goes on to say that when people begin to experience age-related memory lapses, it can lead to a lot of anxiety about their genetic predisposition to Alzheimer's. Ken asks Rudy to talk about the lifestyle factors that play into whether someone predisposed to develop Alzheimer's can stave off or avoid disease development. [00:26:09] Ken explains that aging appears to intensify when people stop challenging themselves with new things. Given this, Ken asks Rudy what his thoughts are on challenging our brains as they age to protect our cognitive abilities. [00:29:08] Ken asks Rudy about the principal advances in...

In part two of our interview with Dr. Rudy Tanzi, host Meryl Comer, asked about the different brain health supplements currently on the market and their ability to increase cognitive longevity.  Dr. Tanzi, Director of the Genetics and Aging Research Unit, Director of The McCance Center for Brain Health at Massachusetts General Hospital, and Kennedy Professor of Neurology at Harvard Medical School also spoke about the role AI plays in accelerating clinical trials. You won't want to miss part 2 of the interview!SHIELD - Sleep, Handle stress, Interact with others, Exercise, Learn new things, DietSupport the show

Brain health and lifestyle interventions play an important role in longevity.  Dr. Rudy Tanzi, Director of the Genetics and Aging Research Unit, Director of The McCance Center for Brain Health at Massachusetts General Hospital, and Kennedy Professor of Neurology at Harvard Medical School, spoke with host Meryl Comer about the latest brain health research. Dr. Tanzi explains the tools for presymptomatic detection and the importance of early diagnosis. Listen as they discuss the benefits of a healthy diet and exercise, and what he's learned about super agers. You won't want to miss this episode! SHIELD - Sleep, Handle stress, Interact with others, Exercise,  Learn new things, DietSupport the show

Today's Episode Dr. Raj talks with Dr. Rudy Tanzi about his work in Alzheimer's Disease research, his acronym SHIELD for evading its progression, and how his background as a musician has intersected with this work.  Today's Guest Dr. Tanzi is the Vice-Chair of Neurology, Director of the Genetics and Aging Research Unit, Co-Director of the Henry and Allison McCance Center for Brain Health, and Co-Director of the MassGeneral Institute for Neurodegenerative Disease at Massachusetts General Hospital. He also serves as the Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard Medical School. Dr. Tanzi received his BS (microbiology) and BA (history) at the University of Rochester in 1980 and his PhD (neurobiology) at Harvard Medical School in 1990. Dr. Tanzi co-discovered the first Alzheimer's disease (AD) gene, the amyloid precursor protein (APP) gene, and the two other early-onset familial AD genes, presenilin 1 and presenilin 2. As leader of the Cure Alzheimer's Fund Alzheimer's Genome Project, Dr. Tanzi identified several other AD genes, including CD33, the first AD gene shown to regulate neuroinflammation. He also discovered the Wilson's disease gene and other neurological disease genes. Dr. Tanzi's team was the first to use human stem cells to create three-dimensional neural-glial; cell culture organoids of AD, dubbed “Alzheimer's-in-a-Dish”. This model was the first to recapitulate all three key AD pathological hallmarks in vitro, and first to definitively show that amyloid plaques directly cause neurofibrillary tangles - and also made drug screening for AD faster and more cost-effective. Using this system, Dr. Tanzi has developed several novel therapies for AD including gamma secretase modulators targeting amyloid pathology and AMX0035, which was already successful in a clinical trial of ALS and now seeking FDA approval. Dr. Tanzi also discovered that beta-amyloid plays a functional role in the brain as an anti-microbial peptide, supporting a role for infection in AD pathology. Dr. Tanzi serves as Chair of the Cure Alzheimer's Fund Research Leadership Group and numerous advisory and editorial boards. He has been named to TIME magazine's list of TIME100 Most Influential People in the World. Dr. Tanzi is a New York Times bestselling author who has co-authored the books Decoding Darkness, and the bestsellers Super Brain, Super Genes, and The Healing Self with Dr. Deepak Chopra. Dr. Tanzi has hosted several shows on public television, regularly appears on television news programs, and has testified to Congress on both Alzheimer's disease and brain health. About Dr. Raj Dr Raj is a quadruple board certified physician and associate professor at the University of Southern California. He was a co-host on the TNT series Chasing the Cure with Ann Curry, a regular on the TV Show The Doctors for the past 7 seasons and has a weekly medical segment on ABC news Los Angeles. Want more Dr. Raj? Check out the Beyond the Pearls lecture series! The Ultimate High Yield Bundle: The complete review of high-yield clinical medicine topics necessary for graduate medical education board exams including NBME, USMLE Steps 1/2/3, ITE and ABIM Boards. You can also listen to the Beyond the Pearls podcast. Check out our other shows: Physiology by Physeo Step 1 Success Stories The InsideTheBoards Study Smarter Podcast The InsideTheBoards Podcast Produced by Ars Longa Media To learn more about us and this podcast, visit arslonga.media. You can leave feedback or suggestions at arslonga.media/contact or by emailing info@arslonga.media. Produced by: Christopher Breitigan and Erin McCue. Executive Producer: Patrick C. Beeman, MD Legal Stuff The information presented in this podcast is intended for educational purposes only and should not be construed as professional or medical advice. Learn more about your ad choices. Visit megaphone.fm/adchoices

Judith Warner speaks with Dr. Rudolph Tanzi, a neurologist and professor at Harvard University, about the possible causes of and coming treatments for Alzheimer's Disease. One of the most complex and mysterious diseases ever known, Alzheimer's has been the focus of Dr. Tanzi's professional life for forty years; in 1987 he co-discovered the first gene that causes early onset Alzheimer's as a graduate student.  DR. RUDOLPH TANZIi is the Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard Medical School and Vice-Chair of the Neurology Department at Massachusetts General Hospital where he also serves as the Director of the Genetics and Aging Research Unit. A transcript of their conversation can be found at Aventine.org/podcast. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices

In this episode Dr Tanzi discusses whether Alzheimer's and other brain diseases are happening at a younger age and why that might be, along with his own protocol to maintaining a young and healthy mind! Dr. Rudolph Tanzi is the Director of the Genetics and Aging Research Unit, Co-Director of the McCance Center for Brain Health, Co-Director of the Mass General Institute for Neurodegenerative Disease, and Vice-Chair of Neurology (Research), at Massachusetts General Hospital, and the Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard Medical School. Dr. Tanzi co-discovered the first three Alzheimer's disease genes, including APP and directs the Cure Alzheimer's Fund Alzheimer's Genome Project, which identified the first neuroinflammation-related Alzheimer's gene, CD33. He has also been developing therapies for treating and preventing AD using 3D human neural glial culture models of AD and is now testing them in various clinical trials. Dr. Tanzi has published over 600 papers, received numerous awards, including the Metropolitan Life Award, Potamkin Prize, Smithsonian American Ingenuity Award, and was one of the TIME100 Most Influential People in the World. Dr. Tanzi is a New York Times bestselling author, who co-authored “Decoding Darkness” “Super Brain”, “Super Genes”, and “The Healing Self”. He has also hosted three PBS shows and made numerous appearances on network and cable news and medical television shows. In his spare time, he plays keyboards for Joe Perry, Aerosmith and other musicians. Professor Tanzi's page at Harvard https://brain.harvard.edu/?people=rudolph-e-tanzi Books by Professor Tanzi https://amzn.to/3kyqxVQ Super Genes: Unlock the Astonishing Power of Your DNA for Optimum Health and Well-Being https://amzn.to/3zsenSl The Healing Self: A Revolutionary New Plan to Supercharge Your Immunity and Stay Well for Life https://amzn.to/3kwwwKx Super Brain: Unleashing the Explosive Power of Your Mind to Maximize Health, Happiness, and Spiritual Well-Being https://amzn.to/3zx5h6Q Decoding Darkness: The Search For The Genetic Causes Of Alzheimer's Disease If you would like to support our channel, we'd love a coffee ☕…thank you! https://www.buymeacoffee.com/mhealthspan You can also find us on YouTube at https://www.youtube.com/c/modernhealthspan 15% off Bulletproof products at https://www.bulletproof.com/ with discount code HEALTHSPAN15. Renue By Science 10% discount code MHS at https://renuebyscience.com/all-products-2/ 10% off all products at DoNotAge with code MODERNHEALTHSPAN at https://donotage.org/

In this episode Dr Tanzi talks about some of the future potential options are to treat Alzheimer's once it has started and neural inflammation has set in. Dr. Rudolph Tanzi is the Director of the Genetics and Aging Research Unit, Co-Director of the McCance Center for Brain Health, Co-Director of the Mass General Institute for Neurodegenerative Disease, and Vice-Chair of Neurology (Research), at Massachusetts General Hospital, and the Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard Medical School. Dr. Tanzi co-discovered the first three Alzheimer's disease genes, including APP and directs the Cure Alzheimer's Fund Alzheimer's Genome Project, which identified the first neuroinflammation-related Alzheimer's gene, CD33. He has also been developing therapies for treating and preventing AD using 3D human neural glial culture models of AD and is now testing them in various clinical trials. Dr. Tanzi has published over 600 papers, received numerous awards, including the Metropolitan Life Award, Potamkin Prize, Smithsonian American Ingenuity Award, and was one of the TIME100 Most Influential People in the World. Dr. Tanzi is a New York Times bestselling author, who co-authored “Decoding Darkness” “Super Brain”, “Super Genes”, and “The Healing Self”. He has also hosted three PBS shows and made numerous appearances on network and cable news and medical television shows. In his spare time, he plays keyboards for Joe Perry, Aerosmith and other musicians. Professor Tanzi's page at Harvard https://brain.harvard.edu/?people=rudolph-e-tanzi Books by Professor Tanzi https://amzn.to/3kyqxVQ Super Genes: Unlock the Astonishing Power of Your DNA for Optimum Health and Well-Being https://amzn.to/3zsenSl The Healing Self: A Revolutionary New Plan to Supercharge Your Immunity and Stay Well for Life https://amzn.to/3kwwwKx Super Brain: Unleashing the Explosive Power of Your Mind to Maximize Health, Happiness, and Spiritual Well-Being https://amzn.to/3zx5h6Q Decoding Darkness: The Search For The Genetic Causes Of Alzheimer's Disease If you would like to support our channel, we'd love a coffee ☕…thank you! https://www.buymeacoffee.com/mhealthspan You can also find us on YouTube at https://www.youtube.com/c/modernhealthspan 15% off Bulletproof products at https://www.bulletproof.com/ with discount code HEALTHSPAN15. Renue By Science 10% discount code MHS at https://renuebyscience.com/all-products-2/ 10% off all products at DoNotAge with code MODERNHEALTHSPAN at https://donotage.org/

In this episode Professor Tanzi talks about SHIELD, his acronym for the things that you can do to protect your brain. S - Sleep, H - Handle Stress, I - Interactions with friends, E - Exercise, L - Learn new things and D - Diet and we dive into detail on a few of them. Dr. Rudolph Tanzi is the Director of the Genetics and Aging Research Unit, Co-Director of the McCance Center for Brain Health, Co-Director of the Mass General Institute for Neurodegenerative Disease, and Vice-Chair of Neurology (Research), at Massachusetts General Hospital, and the Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard Medical School. Dr. Tanzi co-discovered the first three Alzheimer's disease genes, including APP and directs the Cure Alzheimer's Fund Alzheimer's Genome Project, which identified the first neuroinflammation-related Alzheimer's gene, CD33. He has also been developing therapies for treating and preventing AD using 3D human neural glial culture models of AD and is now testing them in various clinical trials. Dr. Tanzi has published over 600 papers, received numerous awards, including the Metropolitan Life Award, Potamkin Prize, Smithsonian American Ingenuity Award, and was one of the TIME100 Most Influential People in the World. Dr. Tanzi is a New York Times bestselling author, who co-authored “Decoding Darkness” “Super Brain”, “Super Genes”, and “The Healing Self”. He has also hosted three PBS shows and made numerous appearances on network and cable news and medical television shows. In his spare time, he plays keyboards for Joe Perry, Aerosmith and other musicians. Professor Tanzi's page at Harvard https://brain.harvard.edu/?people=rudolph-e-tanzi Books by Professor Tanzi https://amzn.to/3kyqxVQ Super Genes: Unlock the Astonishing Power of Your DNA for Optimum Health and Well-Being https://amzn.to/3zsenSl The Healing Self: A Revolutionary New Plan to Supercharge Your Immunity and Stay Well for Life https://amzn.to/3kwwwKx Super Brain: Unleashing the Explosive Power of Your Mind to Maximize Health, Happiness, and Spiritual Well-Being https://amzn.to/3zx5h6Q Decoding Darkness: The Search For The Genetic Causes Of Alzheimer's Disease If you would like to support our channel, we'd love a coffee ☕…thank you! https://www.buymeacoffee.com/mhealthspan You can also find us on YouTube at https://www.youtube.com/c/modernhealthspan 15% off Bulletproof products at https://www.bulletproof.com/ with discount code HEALTHSPAN15. Renue By Science 10% discount code MHS at https://renuebyscience.com/all-products-2/ 10% off all products at DoNotAge with code MODERNHEALTHSPAN at https://donotage.org/

In this episode Professor Tanzi talks about the causes of Alzheimer's, from the plaques and tangles to neural inflammation, and what treatments exist for these symptoms. Dr. Rudolph Tanzi is the Director of the Genetics and Aging Research Unit, Co-Director of the McCance Center for Brain Health, Co-Director of the Mass General Institute for Neurodegenerative Disease, and Vice-Chair of Neurology (Research), at Massachusetts General Hospital, and the Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard Medical School. Dr. Tanzi co-discovered the first three Alzheimer's disease genes, including APP and directs the Cure Alzheimer's Fund Alzheimer's Genome Project, which identified the first neuroinflammation-related Alzheimer's gene, CD33. He has also been developing therapies for treating and preventing AD using 3D human neural glial culture models of AD and is now testing them in various clinical trials. Dr. Tanzi has published over 600 papers, received numerous awards, including the Metropolitan Life Award, Potamkin Prize, Smithsonian American Ingenuity Award, and was one of the TIME100 Most Influential People in the World. Dr. Tanzi is a New York Times bestselling author, who co-authored “Decoding Darkness” “Super Brain”, “Super Genes”, and “The Healing Self”. He has also hosted three PBS shows and made numerous appearances on network and cable news and medical television shows. In his spare time, he plays keyboards for Joe Perry, Aerosmith and other musicians. Professor Tanzi's page at Harvard https://brain.harvard.edu/?people=rudolph-e-tanzi Books by Professor Tanzi https://amzn.to/3kyqxVQ Super Genes: Unlock the Astonishing Power of Your DNA for Optimum Health and Well-Being https://amzn.to/3zsenSl The Healing Self: A Revolutionary New Plan to Supercharge Your Immunity and Stay Well for Life https://amzn.to/3kwwwKx Super Brain: Unleashing the Explosive Power of Your Mind to Maximize Health, Happiness, and Spiritual Well-Being https://amzn.to/3zx5h6Q Decoding Darkness: The Search For The Genetic Causes Of Alzheimer's Disease If you would like to support our channel, we'd love a coffee ☕…thank you! https://www.buymeacoffee.com/mhealthspan You can also find us on YouTube at https://www.youtube.com/c/modernhealthspan 15% off Bulletproof products at https://www.bulletproof.com/ with discount code HEALTHSPAN15. Renue By Science 10% discount code MHS at https://renuebyscience.com/all-products-2/ 10% off all products at DoNotAge with code MODERNHEALTHSPAN at https://donotage.org/

Dr. Rudolph Tanzi is the Director of the Genetics and Aging Research Unit, Co-Director of the McCance Center for Brain Health, Co-Director of the Mass General Institute for Neurodegenerative Disease, and Vice-Chair of Neurology (Research), at Massachusetts General Hospital, and the Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard Medical School. Dr. Tanzi co-discovered the first three Alzheimer's disease genes, including APP and directs the Cure Alzheimer's Fund Alzheimer's Genome Project, which identified the first neuroinflammation-related Alzheimer's gene, CD33. He has also been developing therapies for treating and preventing AD using 3D human neural glial culture models of AD and is now testing them in various clinical trials. Dr. Tanzi has published over 600 papers, received numerous awards, including the Metropolitan Life Award, Potamkin Prize, Smithsonian American Ingenuity Award, and was one of the TIME100 Most Influential People in the World. Dr. Tanzi is a New York Times bestselling author, who co-authored “Decoding Darkness” “Super Brain”, “Super Genes”, and “The Healing Self”. He has also hosted three PBS shows and made numerous appearances on network and cable news and medical television shows. In his spare time, he plays keyboards for Joe Perry, Aerosmith and other musicians. Professor Tanzi's page at Harvard https://brain.harvard.edu/?people=rudolph-e-tanzi Books by Professor Tanzi https://amzn.to/3kyqxVQ Super Genes: Unlock the Astonishing Power of Your DNA for Optimum Health and Well-Being https://amzn.to/3zsenSl The Healing Self: A Revolutionary New Plan to Supercharge Your Immunity and Stay Well for Life https://amzn.to/3kwwwKx Super Brain: Unleashing the Explosive Power of Your Mind to Maximize Health, Happiness, and Spiritual Well-Being https://amzn.to/3zx5h6Q Decoding Darkness: The Search For The Genetic Causes Of Alzheimer's Disease If you would like to support our channel, we'd love a coffee ☕…thank you! https://www.buymeacoffee.com/mhealthspan You can also find us on YouTube at https://www.youtube.com/c/modernhealthspan 15% off Bulletproof products at https://www.bulletproof.com/ with discount code HEALTHSPAN15. Renue By Science 10% discount code MHS at https://renuebyscience.com/all-products-2/ 10% off all products at DoNotAge with code MODERNHEALTHSPAN at https://donotage.org/

Dr. Tanzi is the Vice-Chair of Neurology, Director of the Genetics and Aging Research Unit, Co-Director of the Henry and Allison McCance Center for Brain Health, and Co-Director of the MassGeneral Institute for Neurodegenerative Disease at Massachusetts General Hospital. He also serves as the Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard Medical School. Dr. Tanzi received his B.S. (microbiology) and B.A. (history) at the University of Rochester in 1980 and his Ph.D. (neurobiology) at Harvard Medical School in 1990. Dr. Tanzi was a key member of the teams that discovered the first Alzheimer's disease (AD) gene, the amyloid precursor protein (APP) gene, and the two other early-onset familial AD genes, presenilin 1 and presenilin 2. As leader of the Cure Alzheimer's Fund Alzheimer's Genome Project, Dr. Tanzi identified several other AD genes, including CD33, the first AD gene shown to regulate neuroinflammation in AD. He also discovered the Wilson's disease gene and several other neurological disease genes. Dr. Tanzi's team was the first to use human stem cells to create three-dimensional mini human brain organoids of AD, dubbed “Alzheimer's-in-a-Dish”. This model was the first to recapitulate all three key AD pathological hallmarks. He and his team have successfully used these organoids to screen for approved drugs and natural products that can stop AD brain pathology. Dr. Tanzi has developed several novel therapies for AD including gamma secretase modulators targeting amyloid pathology (Phase 1 planned 2021) and AMX0035, which was already successful in a clinical trial of ALS and now under priority review for approval at the FDA. Dr. Tanzi also discovered that beta-amyloid plays a functional role in the brain as an anti-microbial peptide, supporting a potential role for infection in the etiology of AD. Dr. Tanzi serves as Chair of the Cure Alzheimer's Fund Research Leadership Group and on numerous scientific advisory and editorial boards. He has published over 600 research papers and is one of the top 50 most cited neuroscientists in the world. He has received the highest awards in his field, including the Metropolitan Life Foundation Award, Potamkin Prize, Ronald Reagan Award, Oneness in Humanity Award, Silver Innovator Award, the Smithsonian American Ingenuity Award, the Brain Research Foundation Award, and the Kary Mullis Award for Medical Research. He has also been named to TIME magazine's list of TIME100 Most Influential People in the World. Dr. Tanzi is also a New York Times bestselling author, who has co-authored the books Decoding Darkness, and bestsellers, Super Brain, Super Genes, and The Healing Self. Dr. Tanzi joins us to mark The One Way Ticket Show's 10th anniversary for our special series--a “one way ticket to optimal mental, physical and spiritual well-being”. On this episode of the program, Dr. Tanzi's conversation with Host Steven Shalowitz includes why today is rapidly becoming the golden age for solving age related brain diseases, lifestyle changes we can make to reduce the risk of Alzheimer's and questions around the brain-consciousness connection. Dr. Tanzi is just one of the engaging personalities featured on The One Way Ticket Show. During the regular season of the program, Host Steven Shalowitz explores with his guests where they would go if given a one way ticket, no coming back. Their destinations may be in the past, present, future, real, imaginary or a state of mind. Steven's guests have included: Nobel Peace Prize Winner, President Jose Ramos-Horta; Legendary Talk Show Host, Dick Cavett; Law Professor, Alan Dershowitz; Fashion Expert, Tim Gunn; Broadcast Legend, Charles Osgood; International Rescue Committee President & CEO, David Miliband; Former Senator, Joe Lieberman; Playwright, David Henry Hwang; Journalist-Humorist-Actor, Mo Rocca; SkyBridge Capital Founder & Co-Managing Partner, Anthony Scaramucci; Abercrombie & Kent Founder, Geoffrey Kent; Travel Expert, Pauline Frommer, as well as leading photographers, artists, chefs, writers, intellectuals, etc.

The world-famous Harvard brain scientist and a musician who plays with Joe Perry and Jonny Depp, tells us what is the latest in brain research, and the very promising future for Alzheimer's prevention and treatment. We are getting very close...Can we detect neurodegenerative diseases, like Alzheimer’s disease, before irreversible damage is done? What supplements can we take to get ahead of neurodegenerative diseases? What role does loneliness play in brain health? Is there a connection between our microbiome and our brain? Dr. Rudolph Tanzi joins us on the SuperAge podcast to dive into these questions and more. Dr. Tanzi is the Vice-Chair of Neurology, Director of the Genetics and Aging Research Unit, Co-Director of the Henry and Allison McCance Center for Brain Health, and Co-Director of the MassGeneral Institute for Neurodegenerative Disease at Massachusetts General Hospital. He also serves as the Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard Medical School. Dr. Tanzi discovered the first Alzheimer’s disease (AD) gene and co-discovered the two other early-onset familial AD genes. His team was the first to use human stem cells to create three-dimensional cell culture organoids of AD, dubbed “Alzheimer’s-in-a-Dish”. This model was the first to recapitulate all three key AD pathological hallmarks in vitro, and first to definitively show that amyloid plaques directly cause neurofibrillary tangles. The 3-D model also made drug screening for AD faster and more cost-effective. Using this system, Dr. Tanzi has developed several novel therapies for Alzheimer’s disease. What you will learn in this episode: How neurons regenerate lost information after damage from a neurodegenerative diseaseThe importance of lifestyle for promoting brain health How we are inducing neurogenesis in mice, and what it means for us The supplements that seem to mimic the benefits of exercise to improve brain functionWhat supplements Dr. Tanzi takes and whyWhat we are learning from Dr. Tanzi’s Alzheimer’s-in-a-Dish researchHow we may be able to detect declining brain health before it leads to neurodegenerative diseasesThe danger of loneliness and lack of social interactionWhat to eat for gut health and how your gut health impacts your brain healthHow Dr. Tanzi is using glasses with light and sound therapy to promote deeper sleep“If you’re going to take fish oil for omega-3s, make sure you’re paying a lot of money for it and it’s triple distilled, just to get those metals out.”“I feel like I’m firing out all cylinders. It not only helps with brain health but a healthy brain helps with mental vitality, as well. “That’s how we are going to stop Alzheimer’s disease. Early detection, early intervention.”“The brain suffers from not being social and from not having social interaction. Loneliness, meaning being alone, and stress about it, increases risk for Alzheimer’s two fold.”“The brain actually depends on the gut and the bacteria there and the metabolites they make from your food to control everything from mood, to the amount of amyloid you make or break or get rid of, to neuro-inflammation.” Donate to the Cure Alzheimer’s Fund to help support research: https://curealz.orgCheck out Dr. Tanzi's music: https://www.n1m.com/rudytanzi

Dr. Rudy Tanzi is a Harvard neuroscientist, Director of the Genetics and Aging Research Unit at Mass General in Boston, and a pioneer in identifying genetic markers for Huntington's and Alzheimer's diseases.

The Royal Commission into Aged Care Quality and Safety continues to hear damning reports about how the sector has been mismanaged. Professor Joseph Ibrahim is Head of the Health Law and Aging Research Unit in the Department of Forensic Medicine at Monash's Victoria Institute of Forensic Medicine, and a practicing consultant physician in geriatric medicine. His paper publised in The Conversation  in July this year, 4 steps to avert a full-blown coronavirus disaster in Victoria's aged care homes, sets out the problems with the sector. Joseph Ibrahim joins me on Listening Notes to discuss the current crisis and what has to change. As Scott Morrison progresses his gas-led Covid recovery plans, community groups are standing up for the environment against enormous odds. A few weeks ago Julia Stockitj told us about the Save Westernport Campaign to prevent AGL from installing a floating regassification terminal at Crib Point on the Mornington Penninsula.Another project attracting strong community opposition is the Santos coal-seam gas project proposed for Narrabri, New South Wales. The New South Wales Department of Planning, Industry and Environment (DPIE) has given the project the green light but the New South Wales Independent Planning Commision (IPC), the body which makes the ultimate decision, has received 23,000 submissions, 98% of which oppose the project. Madeline Taylor ia a lecturer at the University of Sydney Law School specialising in Energy and Natural Resources Law. She argues that DPIE's approval is based on flawed evidence and that Santos' proposed coal seam gas project may endanger critical water supplies, farmland and threatened species.       

As one of the most influential researchers in Neuroscience with over 100,000 citations, an international bestseller and a keyboardist with Aerosmith, Dr. Rudolph Tanzi is a Professor of Neurology at Harvard Medical School. He is also the Vice-Chair of Neurology, Director of the Genetics and Aging Research Unit, Co-Director of the Henry and Allison McCance Center for Brain Health and Co-Director of the MassGeneral Institute for Neurodegenerative Disease at Massachusetts General Hospital. As an avid communicator of brain health, Dr. Tanzi co-discovered some of the first Alzheimer’s disease genes and received the nation’s highest awards in research and innovation. He also discovered the Wilson’s disease gene and contributed to the discovery of several other neurological disease genes. This episode takes you on his journey into science, music, and mindfulness, leaving no doubt that he truly is a legend!

Ira Pastor, ideaXme life sciences ambassador, interviews Dr. Rudolph Tanzi, Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard University, Vice-Chair of Neurology, Director of the Genetics and Aging Research Unit, and Co-Director of the Henry and Allison McCance Center for Brain Health at Massachusetts General Hospital. Ira Pastor Comments: On this episode we are going to journey back to the topic of Alzheimer’s disease (AD), projected to affect over a 100 million people worldwide by mid century.  Dr. Rudolph Tanzi: Dr. Rudolph Tanzi is the Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard University, Vice-Chair of Neurology, Director of the Genetics and Aging Research Unit, and Co-Director of the Henry and Allison McCance Center for Brain Health at Massachusetts General Hospital (MGH), and has been investigating the genetics of neurological disease since the 1980s when he participated in the first study that used genetic markers to find a disease gene for Huntington's disease. In 1990, Dr. Tanzi received his Ph.D. in neurobiology at Harvard Medical School, where his doctoral thesis was on the discovery and isolation of the first Alzheimer's disease gene - the amyloid precursor protein (APP), published in 1987 in Science. Dr. Tanzi's work in Alzheimer's disease research: Dr Tanzi co-discovered all three familial early-onset Alzheimer's disease (FAD) genes and several other neurological disease genes including those responsible for Wilson’s disease. Dr Tanzi also serves as Chair of the Cure Alzheimer's Fund Research Leadership Group and leader of the Cure Alzheimer's Fund Alzheimer’s Genome Project, where he has carried out multiple genome wide association studies (GWAS) of thousands of Alzheimer’s families leading to the identification of novel AD candidate genes, including CD33, and ADAM10 genes. Dr Tanzi has also worked on the role of zinc and copper in AD, on gamma secretase modulators for the prevention and treatment of Alzheimer's, and on human stem cells to create an “Alzheimer’s-in-a-Dish”, three-dimensional neural culture system, that was the first to recapitulate both pathological hallmarks of Alzheimer’s disease. Dr. Tanzi has published over 500 scientific papers, including the top three most cited papers in the field of Alzheimer's disease research. Dr. Tanzi also co-authored the books "Decoding Darkness: The Search the Genetic Causes of Alzheimer's Disease", the New York Times Best Selling book “Super Brain: Unleashing the Explosive Power of Your Mind to Maximize Health, Happiness, and Spiritual Well-Being”, "Super Genes: Unlock the Astonishing Power of Your DNA for Optimum Health and Well-Being", and "The Healing Self: A Revolutionary New Plan to Supercharge Your Immunity and Stay Well for Life" with Deepak Chopra. Dr. Tanzi in the Media Dr. Tanzi has made numerous television appearances on shows such as CBS This Morning and Dr. Oz. He also hosts the shows "Super Brain with Dr. Rudy Tanzi", "Super Genes with Dr. Rudy Tanzi" and "The Brain Body Mind Connection with Dr. Rudy Tanzi and Dr. Deepak Chopra" on PBS television. In addition to his work in AD and brain health, Dr. Tanzi has wide ranging musical pursuits. Dr Tanzi professionally plays keyboards, most recently with Joe Perry and Aerosmith. He also co-wrote the song tribute to Alzheimer's patients called "Remember Me", performed by singer Chris Mann. He plays keyboards on the albums: "Aerosmith: Music from Another Dimension", and "Joe Perry: Switzerland Manifesto." On this episode we will hear from Dr Tanzi about: His background; how he developed an interest in neurobiology and the domain of AD. His work on the Alzheimer's Disease - Infectious Disease connection and the Alzheimer's Disease - Neuro-inflammation connection. His work with stem cells and regenerative medicine. His work in the area of aging, brain health and the "psycho-biologic" aspects of health and wellness. About mental health and self care during the COVID-19 crisis. Credits: Ira Pastor interview video, text, and audio. Follow Ira Pastor on Twitter:@IraSamuelPastor If you liked this interview, be sure to check out ourinterviewexploring the viral causes of Alzheimer's! Follow ideaXme on Twitter:@ideaxm On Instagram:@ideaxme Find ideaXme across the internet including on iTunes,SoundCloud,Radio Public,TuneIn Radio,I Heart Radio, Google Podcasts, Spotify and more. ideaXme is a global podcast, creator series and mentor programme. Our mission: Move the human story forward!™ ideaXme Ltd.

We talk to Rudy Tanzi, professor of neurology at Harvard University and Director of the Genetics and Aging Research Unit at Massachusetts General Hospital, about what he’s learned from over 35 years of research on the brain.

For this Alzheimer’s Talks presented by UsAgainstAlzheimer's, we were honored to have Dr. Rudy Tanzi share with us his fascinating new work on a microbial hypothesis of the causes of Alzheimer’s disease. Dr. Tanzi is the Vice Chair of Neurology and Director of the Genetics and Aging Research Unit at Massachusetts General Hospital and a Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard Medical School. He was chosen by the Geoffrey Beene Foundation as a ‘Rock Star of Science’ and is a Founding Member of our ResearchersAgainstAlzheimer’s network. Support the show (https://www.usagainstalzheimers.org/ways-donate)

The Sages & Scientists Symposium presents “Genetics, Epigenetics, and Neuroscience” with Deepak Chopra, MD, of UC San Diego School of Medicine; and Rudolph Tanzi, PhD, Professor of Neurology at Harvard University and Director of the Genetics and Aging Research Unit at Massachusetts General Hospital. Joining them is Jonathan Rosand, also a Professor of Neurology at Harvard Medical School. Series: "Wellbeing " [Health and Medicine] [Show ID: 31448]

The Sages & Scientists Symposium presents “Genetics, Epigenetics, and Neuroscience” with Deepak Chopra, MD, of UC San Diego School of Medicine; and Rudolph Tanzi, PhD, Professor of Neurology at Harvard University and Director of the Genetics and Aging Research Unit at Massachusetts General Hospital. Joining them is Jonathan Rosand, also a Professor of Neurology at Harvard Medical School. Series: "Wellbeing " [Health and Medicine] [Show ID: 31448]

Dr. Rudolph Tanzi is a neuroscientist and renowned researcher at Harvard University. Selected as one of TIME Magazine's 100 most influential people of 2015 for his groundbreaking alzheimer's research, Dr. Tanzi also serves as the Director of the Genetics and Aging Research Unit at Massachusetts General Hospital (MGH). In this interview, Dr. Tanzi shares his perspective on the relation of thought, the “self,” and free will - as well as his perspective on human enhancement and evolution (which he believes will occur at a biological and genetic level, not through a merger with machines).