Podcasts about hallmarks

What if your migraine pattern is becoming more frequent before you even realize it?In this episode of Migraine Heroes Podcast, host Diane Ducarme explores eight subtle signs that episodic migraine may be moving toward a more chronic pattern—from mild headache days and longer recovery periods to increasing sensitivity and more frequent medication use.You'll discover:

Arena Church (Nottingham)Sunday 9th August 2026

Dandies Down Under: Breeding with Integrity and Soft Outlines Laura Reeves sits down with Emma Greenway of Jolly Gaze kennels in Victoria, Australia, for an in-depth conversation on the history, breeding and styling of the Dandie Dinmont Terrier. This episode of the Dandie Dinmont Terrier Diaries is part of Pure Dog Talk's Clubhouse. The series features members of the Club Partnership Program who are working to preserve the knowledge of their legacy breeders. [caption id="attachment_17065" align="alignleft" width="300"] Emma Greenway and two Jolly Gaze puppies.[/caption] Drawing on nearly 40 years of experience, a background as a historian, and a PhD in Australian canine history, Emma shares her unique perspective on how geographic isolation forced her to “interrogate” the breed standard. Whether you are a Dandie devotee or a general student of dog history, this episode offers a masterclass in breeding with integrity, mentoring across borders and staying true to the soul of your breed. From Schnauzers to Dandies: The Early Lessons of SportsmanshipEmma began her journey with Miniature Schnauzers, learning the ropes of grooming, showing and standard analysis from a generous mentor who modeled impeccable sportsmanship and grace in defeat.Her early love for the Dandie Dinmont Terrier eventually led her to seek out the breed, though she faced the hurdle of only one active breeder remaining in Australia at the time. "Generosity breeds generosity... we have to work together and we have to share our knowledge." — Emma Greenway The Quest for the Foundation Bitch: Flying to the UKDetermined to acquire a top-tier foundation bitch, Emma traveled to the UK. She studied the breed standard obsessively and chose a bitch at a Birmingham show purely based on her own standard evaluation rather than the judge's placement.Through the generosity of a prominent UK breeder, Emma secured her foundation bitch in 1992 (arriving in Australia in 1993), which she later bred to a respected male acquired from New Zealand expats. A Historian's Eye on the Australian Dandie Legacy Emma recounts the history of Dandie Dinmonts in Australia, noting they were reintroduced in 1969 by Mary McCall (initially a Westie breeder) using imports from the famous Bellmead Kennels.She shares the chilling story of Bellmead maid Peggy Hume, who described the tragic loss of bloodlines during WWII, wheeling down deceased dogs in wheelbarrows due to extreme wartime starvation.Other early Australian pioneers of the breed ultimately drifted away from Dandies because establishing lines and winning against flashy terriers was exceptionally difficult. "Our breed standard says body colour coming well down shoulder and hips gradually, gradually emerging into colour of legs. Not a line. Not a line anywhere. It's a gradual merging. It's natural." — Emma Greenway The Advantage of Isolation: Rejecting the "Cookie-Cutter" RecipeWhile isolation in Australia presented logistical hurdles, Emma credits it as a blessing. Without local handlers or a dominant local show trend to emulate, she was forced to deeply interrogate the breed standard to guide her grooming and breeding choices.She warns against "recipe grooming"—where exhibitors blindly copy winning handlers without understanding why. Interrogating the standard yourself builds a detailed eye for puppies and prevents kennel blindness. Grooming Philosophy: Soft Curves vs. Sharp Lines Coming from Miniature Schnauzers, Emma highlights the stark contrast in grooming: Schnauzers are about sharp, square lines and dramatic skirts.Dandies, by contrast, are defined by soft, natural curves. Emma notes that the standard explicitly calls for the body color to gradually merge into the leg furnishings, rather than displaying a sharp, abrupt line or skirt. "In dandies, we don't have the luxury of throwing everything out. Sometimes you have to go back a bit to go forward a bit. Or sideways." — Emma Greenway Breeding Priorities: Multi-Generational Planning in a "Gene Puddle"Emma describes the reality of breeding a rare breed with highly restricted genetics. Referencing Betty-Anne Stenmark's famous description, she notes that Dandie breeders are working in a "gene puddle" rather than a gene pool, where all living dogs trace back to just two 19th-century stud dogs.Because she is the sole active breeder in her region, Emma must plan 3 to 4 generations ahead to ensure genetic diversity and preserve future combination options.While she predominantly line breeds, she occasionally imports outside lines. Her selection criteria post-outcross focus heavily on keeping puppies that resemble the Jolly Gaze style while selecting for softer, more pet-friendly temperaments. The Hallmarks of a Dandie: Outline, Head and the Power of "Weasley" If summarized, the hallmark of the Dandie Dinmont lies in its outline and headpiece.Emma champions the preservation of the word "Weasley" (present in UK, Canadian, and original standards, but omitted from the US standard in the 1970s), which beautifully captures the breed's distinct curvy silhouette and athletic capability. The Social History of Breed Standards and the Future of Dog Shows Drawing on her PhD research, Emma discusses how modern breed concepts didn't exist before 1820. She notes that while working "utility" drove early types, the 19th-century middle class artificially shaped breed standards to elevate the dogs' social status.Looking ahead, Emma voices concern about the aging community, rising administrative regulations and the lack of young exhibitors learning to groom. She sees Asia's rising middle class as a shining hope for the future of purebred dogs.

Ilkeston Hub Campus Monday 27th July 2026

Arena Church Nottingham2nd August 2026

“Hallmarks of a Healthy Church” Acts 4:32-37 Download From fbcmw.org

Arena Church Mansfield26th July 2026

Arena Church, Belper. 26 July 2026, Andy Richardson, Hallmarks of Success - Living Purely

Jono Kirk, Arena church IlkestonThe 26th of July, 2026

✅ Hallmarks of Health PodcastFIVE PRIMARY POINTS of the PODCASTHeart Rate Variability (HRV) is a powerful predictor of resilience and longevity.HRV reflects the balance between your sympathetic (”fight or flight”) and parasympathetic (”rest and digest”) nervous systems. Higher HRV is associated with fewer surgical complications, lower inflammation, improved recovery, and reduced risk of death. Consumer devices such as Apple Watch, WHOOP, Fitbit, and Oura can track HRV over time, although values should only be compared within the same device.Four simple habits can improve HRV at little or no cost.The podcast highlights four evidence-based strategies to strengthen your nervous system: practice five deep breaths three to four times daily, engage in meaningful conversation to increase social connection, prioritize high-quality sleep, and exercise consistently. Together these habits increase parasympathetic activity, helping your body better withstand physical and psychological stress.Exercise is nature's peptide therapy.Rather than relying on unproven peptide injections, exercise stimulates muscles to release hundreds of beneficial signaling molecules called myokines. These naturally occurring proteins help regulate inflammation, metabolism, brain function, and muscle growth while promoting long-term health. The podcast argues that regular exercise is a safer, evidence-based alternative to commercially marketed peptide injections.Exercise is powerful medicine, including for cancer prevention and recovery.Emerging research suggests exercise-induced myokines may suppress breast cancer cell growth, while regular exercise is associated with roughly a 20% lower risk of breast cancer recurrence and mortality. The broader message is that exercise should be viewed not only as fitness but also as an effective, low-cost therapy for chronic disease prevention.Breathing is an overlooked foundation of vitality.Consistent deep breathing—particularly cyclic sighing and inspiratory muscle training—can improve lung function, increase HRV, reduce stress, and support healthy oxygen saturation. The podcast recommends treating breathing exercises like brushing your teeth: a simple daily habit that strengthens both physical and mental health while improving resilience over time.Copyright, VyVerse, LLC. All Rights Reserved. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit vitalityexplorers.substack.com/subscribe

Mark Hamrick, chief economic analyst at The Hamrick Brief, says that the current affordability crisis has the potential to trigger a recession, if it gets to where there's a slowdown in spending that spills over to impact employment levels. That said, Hamrick says current conditions aren't yet deserving of the label of "economic crisis," even if it feels that way for some individuals and households, effectively the bottom portion of the k-shaped recovery. Still, Hamrick says the remarkable facet of the U.S. economy is that it has been able to avoid recession for this long. Vijay Marolia, chief investment officer at Regal Point Capital, says "Mr. Market is a manic depressive," and is showing those tendencies by getting so excited by positive guidance and potential that the reaction to strong earnings reports has been horrible stock action. He expects that to potentially continue this week, when the focus of earnings season shifts to A.I.-driven companies like Alphabet, Intel and Tesla. Marolia says the market's earnings swings have contributed to an ongoing downturn for tech stocks, though he believes it's more of a buying opportunity than the start of a correction. Plus, with June's inflation reading being partly positive (better than May) mixed with negative (worse than when conflict started with Iran), "Captain Inflation" gives his take on how to best read and cope with the numbers. David Trainer, founder and president at New Constructs, says that while fans may believe Jersey Mike's is "a sub above," the company's initial public offering is a deal from below. While the IPO's launch date hasn't been determined, Trainer says the expected $12 billion valuation is at least double what he thinks the numbers justify, and that the deal — particularly at that level — mostly benefits the private-equity firm that took control of Jersey Mike's in 2025.

David Blyth, Belper Campus, Hallmarks of Success, Relationships, 19th July 2026

Arena Church Ilkeston

Krebsforscher Dr. Moritz Przybilla erklärt, warum sich Krebs meist über viele Jahre entwickelt, welche Rolle Alter, erbliche Veranlagung, Rauchen, Infektionen, Alkohol, Körpergewicht und Bewegung spielen und was an Mythen wie „Zucker füttert Krebs“, Fasten oder ketogener Ernährung dran ist. Außerdem sprechen wir über Biopsien, Immuntherapie, personalisierte Krebsmedizin und die Forschung an Krebsimpfstoffen – und darüber, warum eine Erkrankung niemals eine Frage persönlicher Schuld ist. ------------------------------------------------------------------------ Dominiks Buch zur pflanzenbasierten Sporternährung im UTB-Verlag: https://www.utb.de/doi/book/10.36198/9783838560328 Dominiks Gesundheitscommunity: www.gsundes-hannover.de Dominiks Online-Knie-Kurs: https://gsundes-hannover.de/knieschmerzen/ Dominiks Online-Rücken-Kurs: https://copecart.com/products/34bd5abb/checkout Marcs veganes Online-Fitness-Coaching: https://vegainer-academy.com/ Marcs Online-Kurs: https://www.copecart.com/products/a50f88f2/checkout Moritz Instagram-Kanal: https://www.instagram.com/dr.moritzprzy/?hl=de ------------------------------------------------------------------------ Dieser Podcast wird unterstützt von der Firma Watson Nutrition. Die Firma bietet als einzige umfassend laborgeprüfte Nahrungsergänzungsmittel für eine optimierte Nährstoffversorgung. Zum Angebot zählen Multi-Supplemente, Mono-Supplemente, Sportsupplemente wie Kreatin oder auch Proteinriegel, Shakes und essenzielle Aminosäuren Mit dem Code veganperformance erhältst du 5 % Rabatt auf deine Bestellung.  Zur Firmenwebseite: Watson Nutrition ------------------------------------------------------------------------ Redaktionelle Anmerkungen 00:34:26: Nicht 99 Prozent der DNA sind „ohne Funktion“. Rund 98,5–99 Prozent sind nicht proteincodierend; Teile davon erfüllen regulatorische und strukturelle Aufgaben. 01:40:15–01:41:12: Verarbeitetes Fleisch ist IARC-Gruppe 1, rotes Fleisch dagegen Gruppe 2A. Richtig erklärt wird anschließend, dass die Gruppe die Stärke der Evidenz und nicht die Größe des Risikos beschreibt. 01:40:50–01:41:12: Die Kombinationspille enthält Östrogen und ein Gestagen. Ihre IARC-Einstufung muss organspezifisch erklärt werden: Für einige Krebsarten bestehen Risikoerhöhungen, während das Risiko für Eierstock- und Gebärmutterkörperkrebs sinkt. 01:10:01–01:10:27: Dass Vaping künftig zu „hohen Lungenkrebsraten“ führen werde, bleibt eine Prognose. Eine aktuelle Bewertung hält nikotinhaltige E-Zigaretten zwar für wahrscheinlich krebserregend, bezeichnet das tatsächliche Ausmaß künftiger Krebsfälle aber ausdrücklich als noch unbekannt. Quellenverzeichnis Blass, E., & Ott, P. A. (2021). Advances in the development of personalized neoantigen-based therapeutic cancer vaccines. Nature Reviews Clinical Oncology, 18(4), 215–229. Bouvard, V., Loomis, D., Guyton, K. Z., Grosse, Y., El Ghissassi, F., Benbrahim-Tallaa, L., Guha, N., Mattock, H., & Straif, K. (2015). Carcinogenicity of consumption of red and processed meat. The Lancet Oncology, 16(16), 1599–1600. de Martel, C., Georges, D., Bray, F., Ferlay, J., & Clifford, G. M. (2020). Global burden of cancer attributable to infections in 2018: A worldwide incidence analysis. The Lancet Global Health, 8(2), e180–e190. Drexler, U., Dörfler, J., von Grundherr, J., Erickson, N., & Hübner, J. (2023). Fasting during cancer treatment: A systematic review. Quality of Life Research, 32(5), 1427–1446. Faubert, B., Solmonson, A., & DeBerardinis, R. J. (2020). Metabolic reprogramming and cancer progression. Science, 368(6487), Article eaaw5473. Fink, H., Langselius, O., Vignat, J., Rumgay, H., Rehm, J., Martinez, R. X., Santero, M., Lopez-Perez, L., Inoue, M., Zeng, H., Shield, K., Morgan, E., Ilbawi, A., Bray, F., & Soerjomataram, I. (2026). Global and regional cancer burden attributable to modifiable risk factors to inform prevention. Nature Medicine, 32, 1306–1315. Green, A. C., Williams, G. M., Logan, V., & Strutton, G. M. (2011). Reduced melanoma after regular sunscreen use: Randomized trial follow-up. Journal of Clinical Oncology, 29(3), 257–263. Hanahan, D. (2022). Hallmarks of cancer: New dimensions. Cancer Discovery, 12(1), 31–46. Havel, J. J., Chowell, D., & Chan, T. A. (2019). The evolving landscape of biomarkers for checkpoint inhibitor immunotherapy. Nature Reviews Cancer, 19(3), 133–150. International Agency for Research on Cancer. (2012). A review of human carcinogens: Part A. Pharmaceuticals (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 100A). Lei, J., Ploner, A., Elfström, K. M., Wang, J., Roth, A., Fang, F., Sundström, K., Dillner, J., & Sparén, P. (2020). HPV vaccination and the risk of invasive cervical cancer. The New England Journal of Medicine, 383(14), 1340–1348. Ligibel, J. A., Bohlke, K., May, A. M., Clinton, S. K., Demark-Wahnefried, W., Gilchrist, S. C., Irwin, M. L., Late, M., Mansfield, S., Marshall, T. F., Meyerhardt, J. A., Thomson, C. A., Wood, W. A., & Alfano, C. M. (2022). Exercise, diet, and weight management during cancer treatment: ASCO guideline. Journal of Clinical Oncology, 40(22), 2491–2507. López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2023). Hallmarks of aging: An expanding universe. Cell, 186(2), 243–278. Malone, E. R., Oliva, M., Sabatini, P. J. B., Stockley, T. L., & Siu, L. L. (2020). Molecular profiling for precision cancer therapies. Genome Medicine, 12, Article 8. Martincorena, I., Fowler, J. C., Wabik, A., Lawson, A. R. J., Abascal, F., Hall, M. W. J., Cagan, A., Murai, K., Mahbubani, K. T. A., Stratton, M. R., Fitzgerald, R. C., Handford, P. A., Campbell, P. J., Saeb-Parsy, K., & Jones, P. H. (2018). Somatic mutant clones colonize the human esophagus with age. Science, 362(6417), 911–917. McTiernan, A., Friedenreich, C. M., Katzmarzyk, P. T., Powell, K. E., Macko, R., Buchner, D., Pescatello, L. S., Bloodgood, B., Tennant, B., Vaux-Bjerke, A., George, S. M., Troiano, R. P., & Piercy, K. L. (2019). Physical activity in cancer prevention and survival: A systematic review. Medicine & Science in Sports & Exercise, 51(6), 1252–1261. Muscaritoli, M., Arends, J., Bachmann, P., Baracos, V., Barthelemy, N., Bertz, H., Bozzetti, F., Hütterer, E., Isenring, E., Kaasa, S., Krznaric, Z., Laird, B., Larsson, M., Laviano, A., Mühlebach, S., Oldervoll, L., Ravasco, P., Solheim, T. S., Strasser, F., … Bischoff, S. C. (2021). ESPEN practical guideline: Clinical nutrition in cancer. Clinical Nutrition, 40(5), 2898–2913. National Cancer Institute. (2024a). Common cancer myths and misconceptions. National Cancer Institute. (2024b). Genetic testing for inherited cancer risk: Fact sheet. National Human Genome Research Institute. (2020). Deoxyribonucleic acid (DNA) fact sheet. Robertson, E. G., & Baxter, G. (2011). Tumour seeding following percutaneous needle biopsy: The real story! Clinical Radiology, 66(11), 1007–1014. Schreiber, R. D., Old, L. J., & Smyth, M. J. (2011). Cancer immunoediting: Integrating immunity's roles in cancer suppression and promotion. Science, 331(6024), 1565–1570. Sremanakova, J., Sowerbutts, A. M., & Burden, S. (2018). A systematic review of the use of ketogenic diets in adult patients with cancer. Journal of Human Nutrition and Dietetics, 31(6), 793–802. Stewart, B. W., Marshall, H., Bonevski, B., Griffin, H. J., Hopkins, A. M., Itchins, M., Mazza, C. J., Modi, N. D., Ryan, M., Varlow, M., & Sitas, F. (2026). The carcinogenicity of e-cigarettes: A qualitative risk assessment. Carcinogenesis, 47(1), Article bgag015.

Arena Church Mansfield

Blood Flow Restrictions Exercises & Sauna Sizzles PodcastFive Primary Points of the Podcast* Health is more than the absence of disease—it is the body's ability to protect, adapt, and repair itself.The podcast highlights the emerging concept of the Hallmarks of Health, arguing that true health depends on maintaining strong biologic systems such as protective barriers, effective communication between organs, efficient recycling of damaged cells, healthy biologic rhythms, resilience to stress, and the capacity for repair and regeneration.* Small daily habits strengthen the body's natural defenses.Practical recommendations include protecting the skin, eating a fiber-rich diet or practicing intermittent fasting to support gut health, prioritizing exercise and sleep, and using controlled stressors such as sauna bathing and cold exposure to build resilience. These habits reinforce multiple hallmarks of health simultaneously.* Aging occurs in distinct “waves,” not as a steady decline.Research involving more than 4,300 people suggests that major biologic shifts occur around ages 33, 60, and 78, when molecular and structural changes accelerate. Rather than reacting after these transitions occur, the key is to prepare years in advance by investing consistently in physical, mental, social, and spiritual well-being.* A personal “Vitality Flywheel” provides a framework for thriving throughout life.Dr. Mishra's flywheel consists of Faith, Family & Friends, Fitness, Focus, and Fun. Together, these five elements create momentum for sustained vitality, helping people withstand life's inevitable physical and emotional challenges while improving long-term performance and fulfillment.* Vitality is a skill that must be practiced intentionally every day.The central message is that vitality is not something we inherit or receive from others—it is earned through deliberate daily actions. By strengthening the body, training the mind, nurturing meaningful relationships, serving others, and maintaining a sense of purpose, individuals become more resilient and better equipped to flourish through every stage of life.Copyright VyVerse, LLC. All Rights Reserved. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit vitalityexplorers.substack.com/subscribe

As Christians, not only must we boldly proclaim and hold fast to the good news of Jesus Christ, but we must also attend churches that embrace and proclaim the same message. In today's study, Tom explains why Jesus Christ and the good news of salvation is crucial for every church—and every individual Christian.

A church that does not hold to the biblical Jesus and the biblical gospel is not a true church. In today's message, Pastor Tom explains why the gospel of Jesus Christ is one of the hallmarks of a biblical church.

According to the New Testament, it starts by regularly coming together for corporate worship on the Lord's day, as well as regularly observing the ordinances of believer's baptism and the Lord's table, two ordinances that Scripture commands faithful churches to administer.

Arena Church Mansfield

Today we come to the fourth hallmark, and it's how a biblical church intentionally structures church life to reflect what the Bible teaches. Friend, does your own church place a high priority on that? One that reflects what the Bible actually teaches?

As Tom will show us in today's study, a biblical understanding of man puts into perspective man's condition before a holy God: He is a wretched sinner, one who has rebelled and sinned against a holy God and is thus unable to save himself.

The truth is that a biblical church understands and embraces what the Bible teaches about man: his nature, problems, and their solutions. While the culture continues to understand man through psychology and other philosophies, we, as Christians, must be committed to what the Bible says about man.

In order for a church to be both biblical and spiritually healthy, it's essential they have a high view of God's Word. In other words, they must treat the Bible with the utmost respect as they would God Himself.

For a church to be a biblical church, they must affirm that the Bible is God-breathed, it is sufficient, and it speaks authoritatively for all of life, including how churches should conduct themselves.

Part two of our Christopher Nolan recap takes us from Inception - the movie that made his name as an “IP” director - all the way to the present day and our hellish scramble to get IMAX tickets for The Odyssey. If you haven't got yours yet, what are you waiting for? On our next and final episode, we'll be concluding our 5-year run of Groovy Movies with a special episode discussing this most major cinematic event. References The Film Data Scientist (not the film stats guy, as we called him)The Amazing Digital CircusPatrick H Williams on How IMAX made Nolan a better directorAtonement Dunkirk scene, directed by Joe WrightWatch Mussolini: Son of the Century, directed by Joe Wright on Sky or Apple TVIf you love what we do, please like, subscribe and leave a review!Produced and edited by Lily Austin and James BrailsfordOriginal theme music by James BrailsfordLogo design by Alfie GarlandFollow us: Instagram, TikTok & LetterboxdEmail us: groovymoviespod@gmail.comWebsite: groovymoviespod.co.uk

The JournalFeed podcast for the week of June 29 – July 3, 2026.These are summaries from just 2 of the 5 articles we cover every week! For access to more, please visit JournalFeed.org for details about becoming a member.Monday's Spoon Feed:Consider beta blocker (BB) and calcium channel blocker (CCB) toxicity in patients presenting with bradycardia and hypotension. Hallmarks of treatment are quick action, escalation to vasopressors, high dose insulin (HDI) if initial treatment fails, and subsequent consideration of ECMO and intralipid rescue therapy in the sickest patients.Friday's Spoon Feed:In this retrospective analysis of patients with non-traumatic abdominal pain, increased age was associated with increased CT ordering, increased findings of acute pathology, and increased surgery and hospitalizations. Tenderness on physical exam was less sensitive for adverse outcomes in patients aged ≥60.

On today's program, Tom Pennington demonstrates from Scripture that all biblical churches must have a high view of God—and their philosophy of ministry must flow from that commitment.

As leaders in Christ's church, we don't get to establish our own guiding principles. But rather, we must do exactly what Christ commands. In this series, we will discover several hallmarks that Scripture defines as essential to being a biblical church.

What if the future of aging is no longer defined simply by lifespan, but by how long we can remain mentally sharp, physically active, emotionally connected, and fully engaged with life? In this thought-provoking episode, Dr. Gillian Lockitch speaks with documentary filmmaker,  David Donnelly, director of the acclaimed documentary,  Forever Young, about the rapidly evolving science of longevity and the questions for humanity, emerging alongside the science. Together, they explore the difference between lifespan and healthspan, the growing role of biomarkers, wearables, epigenetics, and lifestyle medicine, and the ethical and emotional implications of extending human life. Listeners will gain insight into the science driving the longevity revolution while reflecting on what it truly means to age well in a technology-driven world. David Donnelly is an award-winning documentary filmmaker and director. His work focuses on science, human performance, creativity, technology, and the evolving human experience. His first internationally distributed documentary, Maestro, explored musical mastery and Estonia's Singing Revolution through the life of conductor Paavo Järvi. He later directed documentaries including Nordic Pulse, Forte, and The Cost of Convenience, examining culture, technology, and human autonomy. In Forever Young, Donnelly spent three years documenting leading longevity scientists and exploring the biological, ethical, and philosophical dimensions of extending human healthspan and lifespan. His work bridges scientific complexity with accessible storytelling that invites audiences to reflect on the future of aging and humanity itself.   Episode Timeline  00:00 – Welcome and introduction  02:35 – The longevity revolution and redefining healthy aging  03:58 – David Donnelly's journey from pre-med student to filmmaker  05:30 – The documentary Maestro and Estonia's Singing Revolution  08:37 – Why longevity science became the focus of Forever Young  10:59 – Dr. Lockitch's personal journey into epigenetics and healthspan  13:17 – Healthspan versus lifespan and the science-fiction future of aging  15:06 – The "Death Doula" concept and the death-positive movement  17:46 – Death meditation, grief, and facing mortality consciously  19:43 – Longevity science, biomarkers, and rethinking how we spend our lives  22:15 – Wearables, biological age testing, and tracking healthspan  26:28 – Hallmarks of aging and emerging biomarkers of longevity  29:01 – Ethical questions around lifespan extension and "escape velocity"  31:13 – Human trials targeting aging itself and the future of longevity medicine  33:27 – Epigenetics, lifestyle medicine, and personal responsibility for health  35:47 – Environment, socioeconomic factors, and the cultural barriers to longevity  37:00 – Digital dementia, screen addiction, and modern threats to brain health  38:40 – The powerful message: Your genes are not your destiny  41:12 – Where to watch Forever Young and connect with David Donnelly   Connect with the work of David Donnelly Forever Young Film Official Website  Forever Young Substack  Watch the documentaries  Forever Young  and Maestro  Call to Action  Subscribe to Growing Older Living Younger on your favorite podcast platform and leave a review to help others discover the show. Join the Growing Older Living Younger Community at Growing Older Living Younger Community  Connect with Dr. Gillian Lockitch at Ask Dr. Gill Official Website or email: askdrgill@gmail.com  Download Guide to Nature's Colorful Antioxidants 2026: Nature's Colorful Antioxidants Guide 

Brian Dunseth joined DJ & PK to talk about the World Cup and what the United State Men's National Team has accomplished to this point.

What if one of the most powerful anti-aging tools already exists within your body? This episode explores autophagy, the body's natural cellular renewal system, and how activating it can support healthy aging and longevity. Longevity expert Leslie Kenny shares her personal journey of reversing autoimmune disease and translating cutting-edge science into practical strategies. Listeners will discover how autophagy promoting spermidine, proper nutrition, and baseline lifestyle habits influence cellular repair, resilience, and biological aging.  Leslie Kenny is the founder of Oxford Healthspan, a company focused on translating longevity science into practical health solutions. She is a longevity researcher with expertise in cellular aging, autophagy, and immune system modulation. Her career includes work in finance and policy before a personal medical crisis led her to transition into health science. She specializes in spermidine research and its role in activating autophagy and influencing the hallmarks of aging. She is co-founder of the Oxford Longevity Project, a nonprofit dedicated to education in healthy aging.  Episode Timeline  00:00 – Welcome and introduction  02:00 – Reframing aging as a modifiable biological process  03:50 – Leslie Kenny's autoimmune diagnosis and turning point  10:50 – Limitations of modern healthcare and the need for prevention  14:50 – What autophagy is and why it matters for longevity  17:00 – Spermidine and its role in cellular renewal pathways  21:30 – Nutrition, mushrooms, and dietary sources of spermidine  24:30 – Hallmarks of aging and systemic cellular decline  31:00 – Development of Primadine and supplement formulation science  37:00 – Practical strategies: fasting, diet, and supplementation  41:30 – Key takeaways on influencing biological agin  Connect with Leslie Kenny  https://oxfordhealthspan.com  Instagram: @lesliesnewprime @oxfordhealthspan @oxfordlongevityproject To try Primadine Spermidine Supplement:Code: GOLY15 Link: https://www.oxfordhealthspan.com/GOLY15 Please note that Dr. Lockitch retired from medical practice and does not diagnose, prescribe for or treat any medical conditions. Before ordering any product discussed in these podcasts, consult your health care practitioner. Connect with Dr. Gillian Lockitch  at https://www.askdrgill.com/ or email: askdrgill@gmail.com  Subscribe to Growing Older Living Younger on your favorite podcast platform and leave a review to help others discover the show.   Join the Growing Older Living Younger Community at https://www.facebook.com/groups/growingolderlivingyoungercommunity  Download Guide to Nature's Colorful Antioxidants 2026 

In anticipation of The Odyssey's release, we're traversing the course of Christopher Nolan's career and plotting his signature hallmarks along the way. Plus: the box office-shattering success of Backrooms and Obsession, and the AI movie showing at Tribeca Film Festival. References Christian Zilko's IndieWire articleNolan's 60 Minutes interview The Nolan Variations: The Movies, Mysteries, and Marvels of Christopher Nolan by Tom ShoneIf you love what we do, please like, subscribe and leave a review!Produced and edited by Lily Austin and James BrailsfordOriginal theme music by James BrailsfordLogo design by Alfie GarlandFollow us: Instagram, TikTok & LetterboxdEmail us: groovymoviespod@gmail.comWebsite: groovymoviespod.co.uk

BUFFALO, NY — June 5, 2026 — A new #review was #published in Volume 18 of Aging on May 15, 2026, titled “Blue period – features of senescence 30 years after beta-galactosidase.” The review was led by first author Chisaka Kuehnemann and corresponding author Christopher D. Wiley from Tufts University. Cellular senescence has emerged as one of the most important biological processes linked to aging and age-related disease. Senescent cells stop dividing in response to stress or damage, yet they remain metabolically active and release a variety of signaling molecules that can influence surrounding tissues. Over the past three decades, evidence has increasingly shown that the accumulation of these cells contributes to chronic inflammation, tissue dysfunction, and many degenerative conditions associated with aging. In this review, the authors examine how the field has evolved since the landmark discovery of senescence-associated beta-galactosidase (SA-β-gal) in 1995. That finding provided one of the first practical methods for identifying senescent cells and helped establish that these cells accumulate in aging tissues. Since then, researchers have identified numerous additional characteristics of senescence and developed new approaches to study their role in health and disease. The review highlights several major features now recognized as hallmarks of senescent cells. These include stable proliferative arrest, increased lysosomal activity, secretion of inflammatory and signaling molecules collectively known as the senescence-associated secretory phenotype (SASP), mitochondrial dysfunction, alterations in nuclear architecture, accumulation of metals and lipofuscin, and enhanced survival despite exposure to cellular stress. Full press release - https://aging-us.net/2026/06/05/thirty-years-after-the-discovery-of-sa-%ce%b2-gal-researchers-revisit-the-hallmarks-of-cellular-senescence/ DOI - https://doi.org/10.18632/aging.206380 Corresponding author - Christopher D. Wiley - christopher.wiley@tufts.edu Abstract video - https://www.youtube.com/watch?v=lfMPJF6No7M Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206380 Keywords - aging, senescence, biomarkers, SASP, cell death To learn more about the journal, please visit https://www.Aging-US.com​​ and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

What he's not telling you, but desperately needs you to know || ⇢ WATCH ON YOUTUBE: https://www.youtube.com/watch?v=aYQmN89ary8 We talk a lot about what being in your feminine does for us, but what does it actually give our men? In this episode, Monica dives into the biological, hormonal, and emotional impact your feminine energy has on him and shares real messages from her husband on what it's like when she's fully in hers (and when she's not). If you've ever needed a reason beyond yourself to embody your feminine, this is the episode. What's inside: 

Your skin has a biological age and for most people, it's not the same as their chronological one. Mayo Clinic published the SkinSpan framework this year specifically to quantify it, and the 12 Hallmarks of Aging now have a direct application to dermal tissue.This raises an uncomfortable question: if you're already optimizing everything below the neck with NAD IVs, peptides, and red light, why is the skincare on your face still operating on a paradigm from 1987?In this new episode of the Biohacking Beauty Podcast, we give you a preview of the keynote we're delivering at Dave Asprey's Beyond Conference and walk you through the 3-pillar framework that replaces traditional anti-aging skincare with longevity science in mind.Because the results you can feel today and results you can measure in ten years are not the same thing. And we think you deserve both.Let's dive in.What's Discussed:(2:29) The gap no one in longevity talks about.(3:06) Why your moisturizer is 38 years behind your supplements.(6:21) The 12 Hallmarks of Aging, decoded.(9:42) Pillar 1: The master pathway of skin aging.(12:18) Why NAD in a jar doesn't work (and what does).(14:22) The cellular housekeeping system that quietly shuts down with age.(15:17) The peptide that affects 32% of your skin's genome.(16:55) Pillar 2: The software updates your cells stop sending.(20:09) The PRP lineage that changed regenerative aesthetics.(22:54) Pillar 3: The pillar our community doesn't want to hear about.(29:09) The protocol, tiered by where you're starting.(37:55) How Young Goose fits into what you're already doing.(40:32) The two tests we're building to measure skin longevity.Find more from Young Goose:Use code PODCAST10 to get 10% off your first purchase, and if you're a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincareHead to younggoose.com/products/youth-body-cream for 20% off

Last week's episode of The Redeemed Man introduced our audience to Matt Garner, The Redeemed's new director of groups and leader development, by giving him the chance to tell his backstory—an outwardly successful but secretly hollow life that was turned around by rediscovering his faith with his wife and family. This week founder Paul Amos talks with Matt about his present—how he first got connected with The Redeemed, what his new role entails, and what he's learned about real male friendship and leadership that he's excited to be sharing with other men in need of direction.Segments/chapters0:00 Intro/The importance of true community with other men4:52 How Matt got involved with The Redeemed8:19 How Matt's concept of male friendship has changed14:13 “When God really wants to use you, he's gonna have to break you”16:56 Matt's current role with The Redeemed21:11 What holds men back from taking on leadership roles25:20 Closing thoughts: What's YOUR next step?Find community, deepen your faith, join the brotherhood for free today at theredeemed.com/join.Visit The Redeemed's website for downloadable discussion question sets,  show notes, inspirational articles, more resources, or to share your testimony.Join our Exclusive Newsletter: Signup today and be the first to get notified on upcoming podcasts and new resources!The Redeemed is an organization giving men from all backgrounds a supportive, judgment-free environment, grounded in Christian love without demanding participation in any faith tradition, where they can open up about their challenges, worries, and failures—and celebrate their triumphs over those struggles.Have a redemption story? Share your redemption story here.Interested in being a guest on our podcast?   Email Nate@theredeemed.comFollow The Redeemed on Social Media: PodcastYouTubeFacebookInstagramLinkedInTwitter 

Part two of this juicy convo is here, and Monica's diving straight in. ⇢ WATCH ON YOUTUBE: https://youtu.be/19sNR5gwNVUIf you haven't listened to Part One yet, go back and do that first. These two episodes together are basically a whole masterclass on healthy vs. unhealthy relationships, and that foundation will help this land so much better.In Part Two, Monica is cutting through the fear-mongering, black-and-white relationship content flooding your feed and getting into what a healthy relationship actually looks and feels like.She gets into:

Your immune system isn't just fighting off colds. It's the foundational system that influences all 14 hallmarks of aging — and when it declines, everything downstream accelerates. In this episode, I sit down with Courtney Van Bussum, COO of Longevity Launch Labs, to dive deep into immunosenescence — the aging of the immune system — and why it starts far earlier than most people realise. We unpack what Stanford's landmark 1000 Immunomes Project revealed about the real driver of biological aging, why your supplement stack might be missing the most important piece, and how we built Re:juvenate Pro (Cell Restore in the US) to target immune aging at its root. We get into the fire station analogy that makes the immune system finally make sense, why 70-80% of your immune system lives in your gut and what that means for barrier health, the science behind four synergistic ingredients — Immune Defense Protein, Immunel colostrum extract, carnosic acid from NZ rosemary, and kawakawa — and why standard colostrum supplements aren't cutting it. We also cover why NSAIDs are impairing your recovery, what CXCL9 is and why most practitioners have never heard of it, Isobel's lymphocyte count recovery story, the immune age calculator app, and why "boost your immune system" is the wrong approach — modulation is everything. This is not another colostrum product. This is upstream immune intervention. Links: Shop Re:juvenate Pro (NZ): https://shop.lisatamati.com/pages/rejuvenate Aevum Labs: https://aevumlabs.co.nz Cell Restore (US practitioners): https://aevumlabs.us Cell Restore (US patients): https://ohphealth.com Longevity Launch Labs: https://longevitylaunch.com Lisa's books: https://shop.lisatamati.com/collections/books Longevity newsletter: https://www.lisatamati.com/lisa More episodes: https://www.lisatamati.com/ptl-podcast/                

Pastor Ben teaches from Acts 11 and shows what a healthy, world-changing church actually looks like. In this passage, we see that it begins with ordinary people whose lives have been transformed by Jesus and who cannot help but share that hope with others. As the Church lives this out, lives are changed, communities are formed, and the Gospel continues to advance. Key Verses // Acts 11 — Give towards what God is doing through Passion City Church: https://passioncitychurch.com/dc/give — Subscribe to our Youtube channel to see more messages https://www.youtube.com/passioncitychurchdc — Follow along with Passion City Church DC: https://www.instagram.com/passioncitydc — Follow along with Pastor Ben Stuart: https://www.instagram.com/ben_stuart_ — Passion City Church is a Jesus church with locations in Atlanta and Washington D.C. For more info on Passion, visit https://passioncitychurch.com Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Frailty isn't just something that happens “later”; it's a gradual loss of resilience that can begin much earlier than most people think. Katy Bowman and Dr. Jeannette Loram unpack what frailty and pre-frailty mean biologically. They explore the five key hallmarks used to identify frailty, including walking speed and grip strength, and how a large proportion of people in their 30s and 40s already fall on the spectrum of pre-frailty.The conversation also explores the muscle–gut connection, explaining how frailty is influenced by exercise, diet, and the health of your microbiome. Katy and Jeannette also discuss the potential for rapid-onset frailty linked to the use of GLP-1 medications.Most importantly, frailty can be reversed and this episode focuses on what you can do. From simple ways to improve resilience through movement, nutrition, and rest, to understanding how your attitude toward aging might influence your resilienceEnhanced Show Notes and Full Transcript00:00 – Intro + Sponsors  01:30 – What Is Frailty (and Pre-Frailty)  03:00 – The 5 Hallmarks of Frailty  10:50 – How Pre-Frailty Can Start in Your 30s  12:40 – Muscle–Gut Connection & the Microbiome  19:40 – Exercise as “Fuel” for Your Microbiome  27:30 – Supplementation and the Psychology of Change  29:50 – GLP-1 Medication & Rapid-Onset Frailty  42:20 – Listener Question: Finding Glute Strength (Sponsored by Peluva)Resources and Books Mentioned:Joyspan by Kerry Burnight Frailty Sets In Far Earlier Than You'd Expect But You Can Reverse It, by David Cox in the New Scientist Frailty and pre-frailty in middle-aged and older adults and its association with multimorbidity and mortality: a prospective analysis of 493 737 biobank participants by Hanlon et al 2018Evidence For The Contribution Of Gut Microbiota To Age-Related Anabolic Resistance by Watson et al 2021Semaglutide Therapy and Accelerated Sarcopenia in Older Adults With Type-2 Diabetes: A 24-Month Retrospective Cohort Study by Ren et al 2025Connect, Move & Learn:Join Our Newsletter: Movement Colored GlassesFollow Katy on SubstackTry Katy's Virtual Studio Free for 7 days!Made Possible By Our Wonderful Sponsors:.My Happy Feet: Toe-spacing socks that gently realign toes for comfortable recovery—take 20% off with code MYDNAIkaria Design: The Soul Seat® offers height-adjustable, multi-position sitting—get 10% off new chairs and desks with code DNA10Venn Design: Beautifully upholstered ball-shaped Air Chairs that encourage dynamic sittingPeluva: Five-toe minimalist shoes that move like you do—take 10% off with code NUTRITIOUSMOVEMENTSmart Playrooms: Beautiful playroom design and movement-rich equipment—save 10% on monkey bars and rock-wall items with code DNA10Movemate: Active standing boards with smoothly articulating wooden slats. Designed to keep you moving without interrupting your focus.Thoughts/questions email us at podcast@nutritiousmovement.comYour Voice on the Podcast: Read The Credits 

Leslie Kenny was told in her 30s that she had five years to live. Diagnosed simultaneously with lupus, rheumatoid arthritis, and Hashimoto's thyroiditis — and told to give up her dream of having children — she did what true Betties do: she refused the prognosis, threw everything she had at it, and got to work. Now 60 years old, Leslie reports a biological age of 21. She is autoimmune disease-free. And she naturally conceived a child at 43. Her recovery journey led her to collaborate with University of Oxford scientists and to discover spermidine — a naturally occurring, food-derived longevity compound that was hiding in plain sight. It's been in our food for millennia, it's in breast milk, and it's in every plant on earth. And it addresses 9 of the 12 hallmarks of ageing identified by science as the root causes of why we get older. For 20% off Primeadine, go to: https://www.oxfordhealthspan.com/DRSTEPHANIE  Episode Overview (timestamps are approximate): (0:00) Intro/Teaser (4:00) What Is Spermidine and Why Do We Lose It? (8:00) Autophagy, Hair, Nails & the Biological Dashboard (17:00) The 12 Hallmarks of Ageing, Explained for Real Life (23:00) mTOR, Muscle Loss, and Why Spermidine Is Different (27:00) Food Sources, Dosage & Lifestyle Levers (38:00) Leslie's Story: The Diagnosis, the Prognosis, the Refusal (55:00) IVIG, Trauma Therapy & the Surprise Pregnancy at 43 (1:18:00) Femspan, Future Research & Where to Find Leslie (1:22:00) The After-Party Thoughts with Dr. Stephani Resources mentioned in the Episode can be found at: https://drstephanieestima.com/podcasts/ep464  We couldn't do it without our sponsors: JUST THRIVE HEALTH - Take the Just Thrive FEEL BETTER challenge today, and save 20% on your first order. Go to https://justthrivehealth.com/better and use the code BETTER to see the difference for yourself. BON CHARGE - Achieve glowing skin, gain more energy, and uplevel your recovery practice with a suite of red light products. Get 15% off at https://boncharge.com/better with code BETTER. HIGHER DOSE - If you're noticing thinning, shedding, or simply want to support scalp and hair health proactively, this is a powerful addition to your routine. Get 15% off the Red Light Hat at https://higherdose.com with code BETTER at checkout. KENETIK - You think carefully about how you fuel your body but are you fueling your brain? Learn more about Kenetik and try it for yourself by going to https://drinkkenetik.com/BETTER and use code BETTER for 15% off QUALIA LIFE - Boost energy, DNA health, and cellular protection. Save 15% at https://qualialife.com/better with code BETTER. ****************************P.S. When you're ready, here are two ways Dr. Stephanie can help you:Subscribe: The Mini Pause — My weekly newsletter packed with the most actionable, evidence-based tools for women 40+ to thrive in midlife.Build Muscle: LIFT — My progressive strength training program designed for women in midlife. Form-focused, joint-friendly, and built for real results. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

It's the day of the Christmas party, and there's excitement in the air! Can you hear the distant snap of a Christmas cracker? No, us neither… Jane and Fi chat building a holiday around Harold Wilson's bungalow, who would play them in their biopics, Austrian sewer tours, and misleading Tube stops. Plus, writer and producer Catherine Carr discusses her book Who's the Favourite? Our new playlist 'Coiled Spring' is up and running: https://open.spotify.com/playlist/4tmoCpbp42ae7R1UY8ofza Our next book club pick is 'A Town Like Alice' by Nevil Shute.Our most asked about book is called 'The Later Years' by Peter Thornton.If you want to contact the show to ask a question and get involved in the conversation then please email us: janeandfi@times.radioFollow us on Instagram! @janeandfiPodcast Producers: Eve SalusburyExecutive Producer: Rosie Cutler Hosted on Acast. See acast.com/privacy for more information.

// GUEST //   Miguel & Carlos   // SPONSORS // Blockware Solutions: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://mining.blockwaresolutions.com/breedlove⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Performance Lab Supplements: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.performancelab.com/breedlove⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ The Farm at Okefenokee: ⁠⁠⁠⁠⁠⁠⁠https://okefarm.com/⁠⁠⁠⁠⁠⁠⁠ Efani — Protect Yourself From SIM Swaps: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.efani.com/breedlove⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠   // PRODUCTS I ENDORSE // Protect your mobile phone from SIM swap attacks: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.efani.com/breedlove⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Lineage Provisions (use discount code BREEDLOVE): ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://lineageprovisions.com/?ref=breedlove_22⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Colorado Craft Beef (use discount code BREEDLOVE): ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://coloradocraftbeef.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Salt of the Earth Electrolytes: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://drinksote.com/breedlove⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Jawzrsize (code RobertBreedlove for 20% off): ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://jawzrsize.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ // UNLOCK THE WISDOM OF THE WORLD'S BEST NON-FICTION BOOKS // ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://course.breedlove.io/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠   // SUBSCRIBE TO THE CLIPS CHANNEL // ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/@robertbreedloveclips2996/videos⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠   // TIMESTAMPS //   0:00 – Stage 2 Episode Trailer 1:26 – Peptides, Nootropics & the Nose-to-Brain Pathway 6:10 – BDNF, Flow States & Cognitive Performance 12:17 – Peptides as Biological Signals 18:58 – The Master Pathways of Growth, Repair & Detox 23:26 – Fasting, Autophagy & Fat Adaptation 30:12 – The Hallmarks of Aging Explained 42:31 – Mine Bitcoin with Blockware Solutions 43:54 – Proactive Health vs Reactive Medicine 48:32 – Seasonal Peptide Protocols 57:11 – Brain Repair, Immune Resilience & Longevity Genes 1:12:40 – Why Timing Matters More Than Dosing 1:35:41 – Performance Lab Supplements 1:36:50 – Signaling vs Forcing the Body 1:52:08 – Metabolic Flexibility & Cellular Recovery 2:07:23 – The Farm at Okefenokee 2:08:35 – Immune System Hierarchy & Long-Term Health 2:29:10 – Cellular Energy, Inflammation & Modern Disease 2:57:11 – Efani: Protect Yourself From SIM Swaps 2:58:17 – Unlock the Wisdom of the Best Non-Fiction Books 2:59:20 – Outro   // PODCAST // Podcast Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://whatismoneypodcast.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Apple Podcast: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://podcasts.apple.com/us/podcast/the-what-is-money-show/id1541404400⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Spotify: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://open.spotify.com/show/25LPvm8EewBGyfQQ1abIsE⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ RSS Feed: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://feeds.simplecast.com/MLdpYXYI⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠   // SUPPORT THIS CHANNEL // Bitcoin: 3D1gfxKZKMtfWaD1bkwiR6JsDzu6e9bZQ7 Sats via Strike: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://strike.me/breedlove22⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Paypal: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.paypal.com/paypalme/RBreedlove⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Venmo: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://account.venmo.com/u/Robert-Breedlove-2⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠   // SOCIAL // Breedlove X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://x.com/Breedlove22⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ WiM? X: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://x.com/WhatisMoneyShow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Linkedin: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/in/breedlove22/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/breedlove_22/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ TikTok: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.tiktok.com/@breedlove22⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Substack: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://breedlove22.substack.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ All My Current Work: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://linktr.ee/robertbreedlove⁠

In this episode of the Future of Fitness Podcast, host Eric Malzone sits down with Chris Mirabile, founder of NOVOS, to unpack the science and business of longevity. Chris shares how surviving a brain tumor as a teenager reshaped his perspective on health and pushed him to study aging at a biological level. The conversation dives into what longevity actually means beyond buzzwords—how it differs from simply living a healthy lifestyle, why healthspan matters just as much as lifespan, and the science behind targeting the biological "hallmarks of aging." Chris also explains why some popular trends like hormone optimization and peptides are more complex than they seem, and how NOVOS approaches longevity by addressing the root cellular mechanisms that drive aging, disease risk, and long-term performance. Key Takeaways:

A secure relationship isn't one where nothing ever goes wrong — it's one where the foundation is strong enough to hold the hard stuff. For many people (especially those with anxious attachment), insecurity doesn't come from being “too sensitive,” but from being in dynamics that lack safety, consistency, or clarity.In this episode, I break down five key qualities that tend to be present in secure relationships, and how they actually feel on a nervous system level.I cover:What emotional safety really looks like (and what it doesn't)Why trust is about reliability and consistency, not just honestyHow secure couples approach conflict and repair after ruptureWhat it means for a relationship to be a secure base rather than a constant projectWhy shared vision and felt commitment are essential for long-term securityWhether you're assessing your current relationship, healing after an insecure one, or wanting to understand what you're moving towards, this episode offers a grounded framework for what relational security is built on — and what helps it endure.Explore my couples course, Secure TogetherFree resources for building secure attachment

Most conversations about longevity focus on tactics. This episode breaks down the biology underneath them. You'll hear a systems level analysis of how insulin signaling, mTOR, mitochondrial function, inflammation, and nutrient sensing interact to determine biological age, disease risk, and long term human performance. This is not surface level biohacking. It is a deep dive into the mechanisms that actually control aging, metabolism, muscle preservation, and brain optimization, and why most anti aging strategies fail when they ignore these foundations. This all-time classic episode from 2024, has host Dave Asprey joined by Mark Hyman, a practicing physician and one of the most respected leaders in functional medicine. Dr. Hyman is the founder and senior advisor of The UltraWellnessCenter, the founder and former head of strategy and innovation at the Cleveland Clinic Center for Functional Medicine, and a long time advocate for treating root causes instead of managing disease. With over 30 years of clinical experience, his work focuses on restoring mitochondrial health, optimizing metabolism, reversing chronic disease, and slowing biological aging using science backed interventions. Together, Dave and Mark dismantle common myths around protein, carnivore diets, ketosis, fasting, supplements, and longevity drugs. They explain why sugar accelerates aging faster than protein, how mTOR must cycle instead of staying suppressed, and why muscle, mitochondria, and metabolic flexibility matter more than calorie restriction. The conversation also covers nootropics, sleep optimization, neuroplasticity, AI driven diagnostics, and how functional medicine reframes aging as a reversible biological process rather than an inevitable decline. You'll learn: • How insulin and nutrient sensing control aging speed • Why mitochondria sit at the center of longevity and disease • The truth about mTOR, fasting, and protein intake • How ketosis and metabolic flexibility protect long term health • Where supplements and nootropics actually fit in brain optimization • Why functional medicine outperforms symptom based care • How AI and advanced testing are reshaping modern medicine Thank you to our sponsors! - MASA Chips | Go to https://www.masachips.com/DAVEASPREY and use code DAVEASPREY for 25% off your first order. -ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. -OneSkin | Try OneSkin for 15% off with code DAVE at https://www.oneskin.co/DAVE. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: longevity biohacking, functional medicine longevity, biological age reversal, mitochondria and aging, mTOR pathway aging, insulin resistance and aging, metabolic flexibility, fasting and longevity, ketosis and metabolism, protein intake and mTOR, muscle and longevity, inflammaging, chronic inflammation aging, mitochondrial dysfunction, nutrient sensing pathways, rapamycin longevity, metformin longevity debate, carnivore diet longevity, sugar and aging, brain optimization longevity, neuroplasticity and aging, sleep optimization biohacking, supplements for longevity, anti aging metabolism, human performance optimization, Dave Asprey longevity, Mark Hyman longevity Resources: • Mark's Website: https://drhyman.com/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 - Trailer 0:45 - Introduction 4:49 - Aging as a Treatable Disease 7:50 - The Hallmarks of Aging 14:23 - Nutrient Sensing and Longevity Switches 17:37 - Time Restricted Eating and Autophagy 20:44 - The Four Longevity Pathways 21:49 - Metformin Debate 25:30 - Ozempic and Weight Loss 28:42 - Rapamycin and mTOR 36:23 - Meat, Protein, and Aging 39:46 - Protein Quality and Muscle Synthesis 45:50 - Protein Timing for Muscle Building 48:08 - Metabolic Flexibility 51:32 - Inflammaging 55:26 - Zombie Cells and Senescence See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.