Podcasts about hallmarks

In anticipation of The Odyssey's release, we're traversing the course of Christopher Nolan's career and plotting his signature hallmarks along the way. Plus: the box office-shattering success of Backrooms and Obsession, and the AI movie showing at Tribeca Film Festival. References Christian Zilko's IndieWire articleNolan's 60 Minutes interview The Nolan Variations: The Movies, Mysteries, and Marvels of Christopher Nolan by Tom ShoneIf you love what we do, please like, subscribe and leave a review!Produced and edited by Lily Austin and James BrailsfordOriginal theme music by James BrailsfordLogo design by Alfie GarlandFollow us: Instagram, TikTok & LetterboxdEmail us: groovymoviespod@gmail.comWebsite: groovymoviespod.co.uk

BUFFALO, NY — June 5, 2026 — A new #review was #published in Volume 18 of Aging on May 15, 2026, titled “Blue period – features of senescence 30 years after beta-galactosidase.” The review was led by first author Chisaka Kuehnemann and corresponding author Christopher D. Wiley from Tufts University. Cellular senescence has emerged as one of the most important biological processes linked to aging and age-related disease. Senescent cells stop dividing in response to stress or damage, yet they remain metabolically active and release a variety of signaling molecules that can influence surrounding tissues. Over the past three decades, evidence has increasingly shown that the accumulation of these cells contributes to chronic inflammation, tissue dysfunction, and many degenerative conditions associated with aging. In this review, the authors examine how the field has evolved since the landmark discovery of senescence-associated beta-galactosidase (SA-β-gal) in 1995. That finding provided one of the first practical methods for identifying senescent cells and helped establish that these cells accumulate in aging tissues. Since then, researchers have identified numerous additional characteristics of senescence and developed new approaches to study their role in health and disease. The review highlights several major features now recognized as hallmarks of senescent cells. These include stable proliferative arrest, increased lysosomal activity, secretion of inflammatory and signaling molecules collectively known as the senescence-associated secretory phenotype (SASP), mitochondrial dysfunction, alterations in nuclear architecture, accumulation of metals and lipofuscin, and enhanced survival despite exposure to cellular stress. Full press release - https://aging-us.net/2026/06/05/thirty-years-after-the-discovery-of-sa-%ce%b2-gal-researchers-revisit-the-hallmarks-of-cellular-senescence/ DOI - https://doi.org/10.18632/aging.206380 Corresponding author - Christopher D. Wiley - christopher.wiley@tufts.edu Abstract video - https://www.youtube.com/watch?v=lfMPJF6No7M Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206380 Keywords - aging, senescence, biomarkers, SASP, cell death To learn more about the journal, please visit https://www.Aging-US.com​​ and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

What he's not telling you, but desperately needs you to know || ⇢ WATCH ON YOUTUBE: https://www.youtube.com/watch?v=aYQmN89ary8 We talk a lot about what being in your feminine does for us, but what does it actually give our men? In this episode, Monica dives into the biological, hormonal, and emotional impact your feminine energy has on him and shares real messages from her husband on what it's like when she's fully in hers (and when she's not). If you've ever needed a reason beyond yourself to embody your feminine, this is the episode. What's inside: 

Your skin has a biological age and for most people, it's not the same as their chronological one. Mayo Clinic published the SkinSpan framework this year specifically to quantify it, and the 12 Hallmarks of Aging now have a direct application to dermal tissue.This raises an uncomfortable question: if you're already optimizing everything below the neck with NAD IVs, peptides, and red light, why is the skincare on your face still operating on a paradigm from 1987?In this new episode of the Biohacking Beauty Podcast, we give you a preview of the keynote we're delivering at Dave Asprey's Beyond Conference and walk you through the 3-pillar framework that replaces traditional anti-aging skincare with longevity science in mind.Because the results you can feel today and results you can measure in ten years are not the same thing. And we think you deserve both.Let's dive in.What's Discussed:(2:29) The gap no one in longevity talks about.(3:06) Why your moisturizer is 38 years behind your supplements.(6:21) The 12 Hallmarks of Aging, decoded.(9:42) Pillar 1: The master pathway of skin aging.(12:18) Why NAD in a jar doesn't work (and what does).(14:22) The cellular housekeeping system that quietly shuts down with age.(15:17) The peptide that affects 32% of your skin's genome.(16:55) Pillar 2: The software updates your cells stop sending.(20:09) The PRP lineage that changed regenerative aesthetics.(22:54) Pillar 3: The pillar our community doesn't want to hear about.(29:09) The protocol, tiered by where you're starting.(37:55) How Young Goose fits into what you're already doing.(40:32) The two tests we're building to measure skin longevity.Find more from Young Goose:Use code PODCAST10 to get 10% off your first purchase, and if you're a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincareHead to younggoose.com/products/youth-body-cream for 20% off

Last week's episode of The Redeemed Man introduced our audience to Matt Garner, The Redeemed's new director of groups and leader development, by giving him the chance to tell his backstory—an outwardly successful but secretly hollow life that was turned around by rediscovering his faith with his wife and family. This week founder Paul Amos talks with Matt about his present—how he first got connected with The Redeemed, what his new role entails, and what he's learned about real male friendship and leadership that he's excited to be sharing with other men in need of direction.Segments/chapters0:00 Intro/The importance of true community with other men4:52 How Matt got involved with The Redeemed8:19 How Matt's concept of male friendship has changed14:13 “When God really wants to use you, he's gonna have to break you”16:56 Matt's current role with The Redeemed21:11 What holds men back from taking on leadership roles25:20 Closing thoughts: What's YOUR next step?Find community, deepen your faith, join the brotherhood for free today at theredeemed.com/join.Visit The Redeemed's website for downloadable discussion question sets,  show notes, inspirational articles, more resources, or to share your testimony.Join our Exclusive Newsletter: Signup today and be the first to get notified on upcoming podcasts and new resources!The Redeemed is an organization giving men from all backgrounds a supportive, judgment-free environment, grounded in Christian love without demanding participation in any faith tradition, where they can open up about their challenges, worries, and failures—and celebrate their triumphs over those struggles.Have a redemption story? Share your redemption story here.Interested in being a guest on our podcast?   Email Nate@theredeemed.comFollow The Redeemed on Social Media: PodcastYouTubeFacebookInstagramLinkedInTwitter 

Derek Sewell | Genesis 17 | The hallmarks of God's people Those who belong to God are those who live by his promises and who walk before him.

This week James continued the 'Sent' series with the 7 Hallmarks of a sent person that we see displayed in Acts 1 & 2.Listen, enjoy and be blessed!Thanks for joining us at All Nations Church, we're so glad you're here. We hope you enjoy this message from our Sunday gathering. If you would like to visit in person, you can join us on Sundays, 10:30AM at the All Nations Centre, Cardiff (CF14 3NY).To connect with us online follow the links below:Website: www.allnationschurch.org.ukInstagram: @allnationschurch_cardiffFacebook: @allnationschurchcardiff

Longevity Science Explained: Mitochondria, DNA Damage, Senescent Cells & Peptides with Greg MacphersonHost Vicki Nguyen introduces One Body, One Life, a longevity-focused show sponsored by Jomei's Fine Foods, and interviews Greg Macpherson, a New Zealand pharmacist and founder of SRW Laboratories. Greg shares how working with residential care patients and discovering “The Hallmarks of Aging” shaped his focus on healthspan versus lifespan, using a Mount Everest analogy and noting healthspan is typically about 10 years shorter than lifespan. He highlights key drivers of aging including DNA damage (with lifestyle strategies like “sunscreen for your cells”), personal viral burden and immune fatigue (including attention to absolute lymphocyte count), mitochondrial decline and targeted antioxidants like mitoquinol, and chronic inflammation linked to oxidative stress. They discuss cellular senescence, fasting, time-restricted eating, exercise, and compounds like fisetin and quercetin, plus emerging areas like stem cells, peptides, biological age testing via DNA methylation, and future cellular “reprogramming,” along with Greg's top lifestyle practices and where to find him (srw.co).

Part two of this juicy convo is here, and Monica's diving straight in. ⇢ WATCH ON YOUTUBE: https://youtu.be/19sNR5gwNVUIf you haven't listened to Part One yet, go back and do that first. These two episodes together are basically a whole masterclass on healthy vs. unhealthy relationships, and that foundation will help this land so much better.In Part Two, Monica is cutting through the fear-mongering, black-and-white relationship content flooding your feed and getting into what a healthy relationship actually looks and feels like.She gets into:

Longevity – Buzzword oder wirklich möglich? PD Dr. Stephan ist top ausgebildet in dem, was guttut (promoviert in Medizin) und dem was schadet (habilitiert in Toxikologie) – und mit seinem riesigen Wissen durch viel berufliche wie private Expertise perfekt, um diese Frage zu beantworten. Im aktuellen Schnack und Snack im Podcast gibt Stephan viele Antworten auf die Fragen, wie das lange, gute Leben gelingen kann, warum er bei Longevity zwischen Gesundheits- und Lebensspanne unterscheidet und warum die Hallmarks of Aging, also die Kennzeichen des Alterns, in den Mitochondrien zu finden sind. Als Vorgeschmack auf sein Buch (unten mehr) beschreibt Stephan schon jetzt, warum für ihn der echte Longevity-Wirkstoff mit seinen diversen Effekten auf biologische Zielgrößen „Lebensstil“ heißt und wie seine Oma ihm schon als Junge Wegweisendes mitgeteilt hat. „Gesundheit ist kein Zufall!“ postuliert Stephan daher voller Überzeugung. Und so liegt die Frage nahe, ob er sich so – wenn Gesundheit eben kein Zufall ist – auch den Boom der Nahrungsergänzungsmittel erklären kann? Ist es vielleicht einfach der große Wunsch nach Kontrolle, wenn's um die eigene Gesundheit geht? Als öffentlich bestellten und vereidigten Sachverständigen für die Risikobewertung von Nahrungsergänzungsmitteln hat Heike einen exzellenten Gesprächspartner zu Gast, der Klarheit in den wilden Westen im Web bringt. Es werden jede Menge Kapseln, Pillen oder auch Dienstleistungen und Reisen angeboten, die in Frage gestellt werden dürfen. Insbesondere, wenn Meinungen über evidenzbasierte Aussagen dominieren. Spannend wird's, wenn Stephan die Unterschiede zwischen Lebensmitteln, Nahrungsergänzungsmittel und Arzneimitteln aufzeigt und warum die lange On-Hold-List der EU ein echtes Problem ist. Stephan, Experte „from soil to cell“, gibt klare Life-Hacks für den Kauf von Produkten (Spoiler: It's easy!), die du direkt anwenden kannst. Viel Freude beim Reinhören! Und wenn du noch mehr Tipps für deine bestmögliche Longevity haben möchtest, wirf mal einen Blick in Stephans aktuelles Buch „Die heimlichen Heldinnen des Stoffwechsels. Superpower Mitochondrien“ (Styria-Verlag, Veröffentlichung am 01.06.2026). Außerdem erfährst du noch mehr über Stephan Barth hinter diesen Links: Website: www.drstephanbarth.com LinkedIn (Stephan gehört zu den Top Voices): https://www.linkedin.com/in/dr-stephan-barth/ Gesundheitsheldinnen: www.gesundheitsheldinnen.de Wenn du mir oder uns von essenZ etwas mitteilen möchtest, schreib uns gern eine E-Mail an: team@essenZ.hamburg. Feedback, Anmerkungen, Fröhliches oder auch konstruktive Kritik sind sehr willkommen! Mehr von uns findest du auch auf unserer Website https://essenz.hamburg/ sowie auf Instagram https://www.instagram.com/essenz.hamburg/ oder Linked https://de.linkedin.com/company/essenz-hamburg Für Kolleg:innen und verwandte Disziplinen gibt es weitere Infos auf der essenZ-wissenswerk-Website: https://www.essenz-wissenswerk.hamburg sowie auf Instagram https://www.instagram.com/essenz.wissenswerk/

Longevity, gesundes Altern und ein aktiv verlängertes Leben stehen im Mittelpunkt dieser Episode des Allianz Gesundheitstalks. Der Auftakt der dreiteiligen Podcast Serie beleuchtet den aktuellen Stand der Altersforschung und zeigt, warum ein langes Leben heute neu gedacht wird: nicht als reines Erreichen hoher Lebensjahre, sondern als Verlängerung gesunder Lebenszeit. Zu Gast ist der Journalist und Bestsellerautor Thomas Schulz (DER SPIEGEL). Auf Basis internationaler Forschung, Einblicke aus dem Silicon Valley und Gesprächen mit führenden Wissenschaftlern erläutert er, wie Künstliche Intelligenz, moderne Medizin und neue Biomarker das Verständnis von Alterungsprozessen grundlegend verändern. Ein zentraler Schwerpunkt liegt auf den biologischen Grundlagen des Alterns, den sogenannten Hallmarks of Aging, sowie auf der Frage, welchen Einfluss Gene, Lebensstil, Bewegung und biologische Fitness tatsächlich auf die Lebenserwartung haben.

Ana is speaking about one of the hallmarks of pentecostalism - Adoration - pure, deep, joyful and passionate worship of Jesus

Hier die Links zur Übersichtsfolge Tumorpatho Teil 1:   Spotify: https://open.spotify.com/episode/7GRxZO9Pu18ChMStCg2UCO?si=9easLBRnTImo1oNVQ5iBlw    Apple: https://podcasts.apple.com/de/podcast/patho-aufs-ohr/id1596735972?i=1000744784709    Podbean: https://pathoaufsohr.podbean.com/e/ubersichtsfolge-tumor-pathologie-teil-1/    Youtube: https://youtu.be/XLgGnr9bujI    Wir freuen uns über euer feedback. Kontakt: sven.perner@pathopodcast.de linkedin.com/in/prof-dr-med-sven-perner-6a771b48 christiane.kuempers@pathopodcast.de linkedin.com/in/pd-dr-med-christiane-charlotte-kümpers-279a382b8   Disclaimer: Der Podcast dient ausschließlich allgemeinen Informationszwecken. Die Informationen dieses Podcast sind kein Ersatz für eine professionelle medizinische oder psychologische Beratung, Diagnose oder Behandlung. Die Nutzung der Informationen oder von Materialien, die mit diesem Podcast verlinkt sind, erfolgt auf eigene Verantwortung. Bei gesundheitlichen Fragen oder Beschwerden sollte ein Arzt/eine Ärztin Ihres Vertrauens konsultiert werden.

Arena Church

Arena Church Ilkeston

Arena Church Ilkeston26th April 2026

Arena Church Mansfield

Arena Church Nottingham26th April 2026

Your immune system isn't just fighting off colds. It's the foundational system that influences all 14 hallmarks of aging — and when it declines, everything downstream accelerates. In this episode, I sit down with Courtney Van Bussum, COO of Longevity Launch Labs, to dive deep into immunosenescence — the aging of the immune system — and why it starts far earlier than most people realise. We unpack what Stanford's landmark 1000 Immunomes Project revealed about the real driver of biological aging, why your supplement stack might be missing the most important piece, and how we built Re:juvenate Pro (Cell Restore in the US) to target immune aging at its root. We get into the fire station analogy that makes the immune system finally make sense, why 70-80% of your immune system lives in your gut and what that means for barrier health, the science behind four synergistic ingredients — Immune Defense Protein, Immunel colostrum extract, carnosic acid from NZ rosemary, and kawakawa — and why standard colostrum supplements aren't cutting it. We also cover why NSAIDs are impairing your recovery, what CXCL9 is and why most practitioners have never heard of it, Isobel's lymphocyte count recovery story, the immune age calculator app, and why "boost your immune system" is the wrong approach — modulation is everything. This is not another colostrum product. This is upstream immune intervention. Links: Shop Re:juvenate Pro (NZ): https://shop.lisatamati.com/pages/rejuvenate Aevum Labs: https://aevumlabs.co.nz Cell Restore (US practitioners): https://aevumlabs.us Cell Restore (US patients): https://ohphealth.com Longevity Launch Labs: https://longevitylaunch.com Lisa's books: https://shop.lisatamati.com/collections/books Longevity newsletter: https://www.lisatamati.com/lisa More episodes: https://www.lisatamati.com/ptl-podcast/                

Pastor Ben teaches from Acts 11 and shows what a healthy, world-changing church actually looks like. In this passage, we see that it begins with ordinary people whose lives have been transformed by Jesus and who cannot help but share that hope with others. As the Church lives this out, lives are changed, communities are formed, and the Gospel continues to advance. Key Verses // Acts 11 — Give towards what God is doing through Passion City Church: https://passioncitychurch.com/dc/give — Subscribe to our Youtube channel to see more messages https://www.youtube.com/passioncitychurchdc — Follow along with Passion City Church DC: https://www.instagram.com/passioncitydc — Follow along with Pastor Ben Stuart: https://www.instagram.com/ben_stuart_ — Passion City Church is a Jesus church with locations in Atlanta and Washington D.C. For more info on Passion, visit https://passioncitychurch.com Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Frailty isn't just something that happens “later”; it's a gradual loss of resilience that can begin much earlier than most people think. Katy Bowman and Dr. Jeannette Loram unpack what frailty and pre-frailty mean biologically. They explore the five key hallmarks used to identify frailty, including walking speed and grip strength, and how a large proportion of people in their 30s and 40s already fall on the spectrum of pre-frailty.The conversation also explores the muscle–gut connection, explaining how frailty is influenced by exercise, diet, and the health of your microbiome. Katy and Jeannette also discuss the potential for rapid-onset frailty linked to the use of GLP-1 medications.Most importantly, frailty can be reversed and this episode focuses on what you can do. From simple ways to improve resilience through movement, nutrition, and rest, to understanding how your attitude toward aging might influence your resilienceEnhanced Show Notes and Full Transcript00:00 – Intro + Sponsors  01:30 – What Is Frailty (and Pre-Frailty)  03:00 – The 5 Hallmarks of Frailty  10:50 – How Pre-Frailty Can Start in Your 30s  12:40 – Muscle–Gut Connection & the Microbiome  19:40 – Exercise as “Fuel” for Your Microbiome  27:30 – Supplementation and the Psychology of Change  29:50 – GLP-1 Medication & Rapid-Onset Frailty  42:20 – Listener Question: Finding Glute Strength (Sponsored by Peluva)Resources and Books Mentioned:Joyspan by Kerry Burnight Frailty Sets In Far Earlier Than You'd Expect But You Can Reverse It, by David Cox in the New Scientist Frailty and pre-frailty in middle-aged and older adults and its association with multimorbidity and mortality: a prospective analysis of 493 737 biobank participants by Hanlon et al 2018Evidence For The Contribution Of Gut Microbiota To Age-Related Anabolic Resistance by Watson et al 2021Semaglutide Therapy and Accelerated Sarcopenia in Older Adults With Type-2 Diabetes: A 24-Month Retrospective Cohort Study by Ren et al 2025Connect, Move & Learn:Join Our Newsletter: Movement Colored GlassesFollow Katy on SubstackTry Katy's Virtual Studio Free for 7 days!Made Possible By Our Wonderful Sponsors:.My Happy Feet: Toe-spacing socks that gently realign toes for comfortable recovery—take 20% off with code MYDNAIkaria Design: The Soul Seat® offers height-adjustable, multi-position sitting—get 10% off new chairs and desks with code DNA10Venn Design: Beautifully upholstered ball-shaped Air Chairs that encourage dynamic sittingPeluva: Five-toe minimalist shoes that move like you do—take 10% off with code NUTRITIOUSMOVEMENTSmart Playrooms: Beautiful playroom design and movement-rich equipment—save 10% on monkey bars and rock-wall items with code DNA10Movemate: Active standing boards with smoothly articulating wooden slats. Designed to keep you moving without interrupting your focus.Thoughts/questions email us at podcast@nutritiousmovement.comYour Voice on the Podcast: Read The Credits 

Leslie Kenny was told in her 30s that she had five years to live. Diagnosed simultaneously with lupus, rheumatoid arthritis, and Hashimoto's thyroiditis — and told to give up her dream of having children — she did what true Betties do: she refused the prognosis, threw everything she had at it, and got to work. Now 60 years old, Leslie reports a biological age of 21. She is autoimmune disease-free. And she naturally conceived a child at 43. Her recovery journey led her to collaborate with University of Oxford scientists and to discover spermidine — a naturally occurring, food-derived longevity compound that was hiding in plain sight. It's been in our food for millennia, it's in breast milk, and it's in every plant on earth. And it addresses 9 of the 12 hallmarks of ageing identified by science as the root causes of why we get older. For 20% off Primeadine, go to: https://www.oxfordhealthspan.com/DRSTEPHANIE  Episode Overview (timestamps are approximate): (0:00) Intro/Teaser (4:00) What Is Spermidine and Why Do We Lose It? (8:00) Autophagy, Hair, Nails & the Biological Dashboard (17:00) The 12 Hallmarks of Ageing, Explained for Real Life (23:00) mTOR, Muscle Loss, and Why Spermidine Is Different (27:00) Food Sources, Dosage & Lifestyle Levers (38:00) Leslie's Story: The Diagnosis, the Prognosis, the Refusal (55:00) IVIG, Trauma Therapy & the Surprise Pregnancy at 43 (1:18:00) Femspan, Future Research & Where to Find Leslie (1:22:00) The After-Party Thoughts with Dr. Stephani Resources mentioned in the Episode can be found at: https://drstephanieestima.com/podcasts/ep464  We couldn't do it without our sponsors: JUST THRIVE HEALTH - Take the Just Thrive FEEL BETTER challenge today, and save 20% on your first order. Go to https://justthrivehealth.com/better and use the code BETTER to see the difference for yourself. BON CHARGE - Achieve glowing skin, gain more energy, and uplevel your recovery practice with a suite of red light products. Get 15% off at https://boncharge.com/better with code BETTER. HIGHER DOSE - If you're noticing thinning, shedding, or simply want to support scalp and hair health proactively, this is a powerful addition to your routine. Get 15% off the Red Light Hat at https://higherdose.com with code BETTER at checkout. KENETIK - You think carefully about how you fuel your body but are you fueling your brain? Learn more about Kenetik and try it for yourself by going to https://drinkkenetik.com/BETTER and use code BETTER for 15% off QUALIA LIFE - Boost energy, DNA health, and cellular protection. Save 15% at https://qualialife.com/better with code BETTER. ****************************P.S. When you're ready, here are two ways Dr. Stephanie can help you:Subscribe: The Mini Pause — My weekly newsletter packed with the most actionable, evidence-based tools for women 40+ to thrive in midlife.Build Muscle: LIFT — My progressive strength training program designed for women in midlife. Form-focused, joint-friendly, and built for real results. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

It's the day of the Christmas party, and there's excitement in the air! Can you hear the distant snap of a Christmas cracker? No, us neither… Jane and Fi chat building a holiday around Harold Wilson's bungalow, who would play them in their biopics, Austrian sewer tours, and misleading Tube stops. Plus, writer and producer Catherine Carr discusses her book Who's the Favourite? Our new playlist 'Coiled Spring' is up and running: https://open.spotify.com/playlist/4tmoCpbp42ae7R1UY8ofza Our next book club pick is 'A Town Like Alice' by Nevil Shute.Our most asked about book is called 'The Later Years' by Peter Thornton.If you want to contact the show to ask a question and get involved in the conversation then please email us: janeandfi@times.radioFollow us on Instagram! @janeandfiPodcast Producers: Eve SalusburyExecutive Producer: Rosie Cutler Hosted on Acast. See acast.com/privacy for more information.

Tim LaComb joined DJ to examine the BYU basketball program as Kevin Young's program enters the NCAA Tournament.

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In this episode of the Future of Fitness Podcast, host Eric Malzone sits down with Chris Mirabile, founder of NOVOS, to unpack the science and business of longevity. Chris shares how surviving a brain tumor as a teenager reshaped his perspective on health and pushed him to study aging at a biological level. The conversation dives into what longevity actually means beyond buzzwords—how it differs from simply living a healthy lifestyle, why healthspan matters just as much as lifespan, and the science behind targeting the biological "hallmarks of aging." Chris also explains why some popular trends like hormone optimization and peptides are more complex than they seem, and how NOVOS approaches longevity by addressing the root cellular mechanisms that drive aging, disease risk, and long-term performance. Key Takeaways:

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Sudan: UN fact-finding mission finds ‘Hallmarks of Genocide' in El Fasher Gaza: OHCHR warns of possible ethnic cleansing South Sudan: WFP scales up aid as conflict deepens hunger crisis 

In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. Louise Hecker, Associate Professor of Medicine at Baylor College of Medicine. Together, they dive into Louise's recent research exploring how psilocybin, the active compound in psychedelic mushrooms, may influence aging biology at the cellular and organismal level.Louise shares the story behind her curiosity about psilocybin, sparked by conversations with a friend and fueled by a lack of scientific answers. She explains how her team overcame regulatory hurdles to study the effects of psilocybin on human cells and aging mice. Their findings showed that psilocybin extended cellular lifespan and reduced hallmarks of aging, such as oxidative stress and DNA damage. In mice, regular dosing improved survival, reversed visible signs of aging, and affected organs beyond the brain.The conversation also covers the challenges of translating these findings into humans, the need for more research on dosing and safety, and the importance of funding in moving this field forward. Louise encourages listeners to stay curious, think beyond established paths, and keep an open mind as new questions and discoveries emerge in the science of aging.Guest-at-a-Glance

A secure relationship isn't one where nothing ever goes wrong — it's one where the foundation is strong enough to hold the hard stuff. For many people (especially those with anxious attachment), insecurity doesn't come from being “too sensitive,” but from being in dynamics that lack safety, consistency, or clarity.In this episode, I break down five key qualities that tend to be present in secure relationships, and how they actually feel on a nervous system level.I cover:What emotional safety really looks like (and what it doesn't)Why trust is about reliability and consistency, not just honestyHow secure couples approach conflict and repair after ruptureWhat it means for a relationship to be a secure base rather than a constant projectWhy shared vision and felt commitment are essential for long-term securityWhether you're assessing your current relationship, healing after an insecure one, or wanting to understand what you're moving towards, this episode offers a grounded framework for what relational security is built on — and what helps it endure.Explore my couples course, Secure TogetherFree resources for building secure attachment

Most strategies fail before they even begin. This book summary reveals the surprising reason why, and what truly effective leaders do instead.

Jon Haley

In this episode of the Ageless Future Podcast, host Cade Archibald reframes aging as a modular, systems-based process rather than a simple function of time. Drawing on the Hallmarks of Aging and the geroscience framework, Cade explores how different biological systems—immune function, mitochondrial health, stem cell signaling, cellular senescence, vascular elasticity, brain plasticity, and nutrient sensing—decline at different rates and influence one another. He explains how chronic inflammation acts as a unifying driver of dysfunction and highlights practical strategies to target specific aging bottlenecks, including nutrition, exercise, mitochondrial optimization, peptides, detoxification, and metabolic support. The core message: aging is not inevitable or uniform—it's engineerable. By focusing on system repair instead of surface-level anti-aging, we can enhance resilience, cognitive function, recovery, and long-term vitality.AGELESS FUTURE:Book Comprehensive Labs: https://agelessfuture.com/longevity-labs/FREE copy of The Peptide Blueprint: https://agelessfuture.com/blueprintSign up for future Health Accelerator Challenges calls LIVE! https://us02web.zoom.us/webinar/register/WN_YZsiUMOzSyqcE8IinC5YEQ#/registrationBooks: https://www.amazon.com/Books-Regan-Archibald/s?rh=n%3A283155%2Cp_27%3ARegan%2BArchibaldArticles: https://medium.com/search?q=Regan+ArchibaldLIKE/FOLLOW/SUBSCRIBE AGELESS FUTURE:YouTube -https://www.youtube.com/@ReganArchibald / https://www.youtube.com/@Ageless.FutureLinkedIn: https://www.linkedin.com/in/regan-archibald-ab70b813Instagram: https://www.instagram.com/ageless.future/Facebook: https://www.facebook.com/AgelessFutureHealth/DISCLAIMER: This video is for educational purposes only and does not provide medical advice, diagnosis, or treatment.  Many of the molecules discussed in this video are research compounds and are not approved by the U.S. Food and Drug Administration (FDA) for any specific medical use, indication, or condition. They are mentioned only in the context of existing scientific literature and ongoing research and are not being recommended, prescribed, sold, or offered through this video.  This content does not endorse or recommend any specific tests, products, procedures, or treatment protocols.References to our clinic are for general educational context only; investigational or non‑approved products are not available for direct ordering or prescribing based solely on viewing this content.  Do not start, stop, or change any medication, peptide, or supplement based on this video. All medical decisions must be made with a licensed prescribing clinician after a proper evaluation. No provider–patient relationship is created by viewing this content or contacting our clinic.  Regan Archibald is a Licensed Acupuncturist and longevity coach. He is not a medical doctor. Cade Archibald is COO and Co-Founder of Ageless Future, also not a medical doctor. All medical decisions, lab ordering, and prescribing in our clinic are performed only by our licensed medical team (MD, APRN, PA).  Viewers should follow the guidance of their own licensed clinicians and local health authorities regarding diagnosis and treatment decisions.

Jon Haley

Jon Haley

In this episode, Dr. Datis Kharrazian explores longevity medicine and the hallmarks of aging and disease. How do early signs of loss of resilience—like cognitive decline or changes in physical appearance—offer clues about our biological age? What can cutting-edge studies, such as the Dunedin Longitudinal Study, teach us about predicting poor aging trajectories and preventing chronic diseases like cardiovascular issues and cancer, before they silently take hold?Dr. Kharrazian uncovers the mechanisms underlying tissue degeneration, explores why resilience is central to healthy aging, and explains how functional medicine clinicians can use biomarkers and in-depth assessments to help shift morbidity later in life. Whether you're a healthcare practitioner, a nutrition enthusiast, or facing chronic health challenges, this episode bridges the gap between complex science and actionable steps you can implement right now.Learn functional longevity strategies from Dr. Datis Kharrazian. Discover how to use personalized nutrition, diet, and lifestyle approaches to optimize healthspan. Enroll in the Longevity Mastery Program at: https://pages.kharrazianinstitute.com/longevityFor patient-oriented functional medicine courses, visit https://drknews.com/online-courses/For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/00:00 "Longevity, Wellness, and Disease"03:51 "Pace and Markers of Aging"09:02 "Aging Mechanisms and Disease Links"13:33 Aging, Resilience, and Clinical Outcomes14:52 "Hallmarks of Aging Explained"20:11 "Aging Tissues and Inflammation"22:18 Mitochondria, Aging, and Vascular Health25:59 Cancer Warning Signs32:21 "Aging's Role in Cancer Progression"33:13 "Functional Health Solutions Podcast"Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

Jon Haley

In this episode, Dr. Kharrazian covers the physiological mechanisms that drive aging and how you can take proactive steps to slow disease progression and extend your healthspan.Learn the foundational concepts of geroscience, the difference between anti-aging appearance medicine and true longevity medicine, and actionable clinical strategies for healthier longevity. You'll learn why maintaining resiliency is key to a healthy, vibrant life, what laboratory markers and lifestyle interventions actually make a difference, and how to spot early signs of aging before they become disease. If you're passionate about functional medicine, working with chronic patients, or simply want to invest in your own healthy future, this conversation is packed with the essentials you need.Learn functional longevity strategies from Dr. Datis Kharrazian. Discover how to use personalized nutrition, diet, and lifestyle approaches to optimize healthspan. Enroll in the Longevity Mastery Program at: https://pages.kharrazianinstitute.com/longevityFor patient-oriented functional medicine courses, visit https://drknews.com/online-courses/For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/00:00 "Exploring Aging, Health, and Longevity"04:43 "Understanding Geroscience and Longevity"09:46 "Hallmarks of Aging Explained"13:36 "Addressing Chronic Inflammaging Challenges"17:15 "Aging Pathophysiology in Practice"18:41 "Restoring Physiological Resiliency"24:11 Extending Human Lifespan Potential25:47 "Secrets of Longevity: Jean Calment"29:28 "Longer Lives, Declining Quality"32:32 "Functional Medicine Resource Hub"Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

Angela talks to Dr. Ash Kapoor, a longevity specialist and cellular health expert, who shares his approach to health that focuses on understanding and addressing the root causes of disease and aging, particularly through the lens of the 12 Hallmarks of Aging.  Dr. Kapoor talks about the fact that true longevity is not just about extending lifespan, but about maximising independence, purposefulness, and fulfilment, explaining that modern stress depletes the body's primary energy source (ATP), forcing it to steal from the immune, hormonal, and nervous systems KEY TAKEAWAYS: Longevity Redefined: True longevity is defined not merely by living longer, but by being independent, purposeful, and pursuing fulfilment until an achievable age of 123. The Root Cause of Decline: All 126,000 known diseases can be traced back to the 12 Hallmarks of Aging, a breakdown in the body's cellular systems that is often driven by chronic modern stress A Strategy for Optimisation: Dr. Kapoor's approach involves a multi-stage strategy of detoxifying (cleaning the liver and gut), repairing (restoring hormones and nutrients, and re-establishing circadian rhythm), and renewing the body's cellular environment The Power of Inner Energy: The core problem is operating on stress-based energy (like cortisol and immune/hormonal reserves) instead of the primary mitochondrial energy (ATP) TIMESTAMPS AND KEY TOPICS: 0:01:25: Defining Longevity: What true "living" means beyond just existing. 0:03:00: The Science of the 12 Hallmarks of Aging and the control we have over them. 0:08:48: The link between the external world (success) and internal depletion (energy crash). 0:18:25: The fundamental strategy: Detox, Repair, and Renew in the correct order. 0:25:05: Understanding hormone depletion: Why the body "steals" hormones and the concept of "restorative hormone therapy." VALUABLE RESOURCES ⁠Join The High Performance Health Community⁠ ⁠Click here⁠ for discounts on all the products I personally use and recommend A BIG thank you to our sponsors who make the show possible Ozlo Sleepbuds® – Fall asleep faster and stay asleep longer | Use code ANGELA at https://ozlosleep.com/angela  for your exclusive discount.•  Go to https://lvluphealth.com/angela  Use code ANGELA for an exclusive 15% off Reverse your biological age in 2026 - join Live Younger, Angela's longevity membership for women.  Click here and use code “VIP” for 30% off. ABOUT THE HOST Angela Foster is an award winning Nutritionist, Health & Performance Coach, Speaker and Host of the High Performance Health podcast. A former Corporate lawyer turned industry leader in biohacking and health optimisation for women, Angela has been featured in various media including Huff Post, Runners world, The Health Optimisation Summit, BrainTap, The Women's Biohacking Conference, Livestrong & Natural Health Magazine. Angela is the creator of BioSyncing®️ a blueprint for ambitious entrepreneurial women to biohack their health so they can 10X how they show up in their business and their family without burning out. CONTACT DETAILS ⁠Instagram⁠ ⁠Facebook⁠ ⁠LinkedIn⁠ Disclaimer: The High Performance Health Podcast is for general information purposes only and do not constitute the practice of professional or coaching advice and no client relationship is formed. The use of information on this podcast, or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be a substitute for medical or other professional advice, diagnosis, or treatment. Users should seek the assistance of their medical doctor or other health care professional for before taking any steps to implement any of the items discussed in this podcast. This Podcast has been brought to you by Disruptive Media. ⁠https://disruptivemedia.co.uk/

In this solo episode of The SuperLife Podcast, Darin Olien dives deep into the true biology of energy—not motivation, not stimulants, not willpower, but the mitochondria themselves. Inspired by a groundbreaking conversation between Dr. Andrew Huberman and Dr. Martin Picard, Darin reframes energy as an emergent property of how we live, not just what we eat or how much we sleep. This episode explores how mitochondria act as signal translators, listening to your food, stress, sleep, movement, emotions, purpose, and environment—and turning those signals into either vitality or depletion. Darin connects cutting-edge mitochondrial science with real-world practices around recovery, meaningful stress, consistency, connection, and alignment, showing how true longevity and resilience are built at the cellular level.     What You'll Learn in This Episode 00:00  – Welcome to SuperLife & the mission of sovereignty and vitality 00:32 – Thera Sage sponsor: family-built healing tech & red light 02:10 – Why this episode is different: diving into cellular energy 02:42 – Inspiration from Huberman & Picard's mitochondria conversation 03:11 – Rethinking mitochondria: not just ATP, but information processors 04:03 – Energy as potential for change, not calories or fuel 04:39 – How thoughts, emotions, food, and stress shape energy 05:05 – Energy is dynamic, adaptive, and responsive to how you live 06:02 – Mitochondria as signal integrators: sleep, hormones, purpose, connection 06:50 – Mitochondria as antennas, not factories 07:16 – Translating life experience into biological energy 08:09 – Why we don't feel "energy," we feel energy flow 08:53 – Flow states, purpose, and why passion creates vitality 09:32 – Different organs, different mitochondrial roles 10:26 – Why energy optimization is not one-size-fits-all 10:49 – Energy resistance: the hidden cause of fatigue and burnout 11:47 – Chronic stress, poor sleep, and ultra-processed food as energy blockers 12:12 – Why recovery is non-negotiable for longevity 12:20 – Caldera Lab sponsor: clean, performance-driven skincare 14:20 – The danger of constant output without recovery 14:45 – Sleep as a mitochondrial reset and repair system 15:40 – Exercise, adaptation, and why recovery completes the signal 16:22 – Intentional stress vs. chronic stress 17:29 – Food as information, not just fuel 18:05 – Time-restricted eating, fresh food, and metabolic signaling 18:27 – Meaning, purpose, and emotional states as cellular inputs 19:23 – Mitochondria, aging, and the potential reversibility of decline 20:06 – SuperLife framework: alignment over optimization 20:37 – Consistency beats intensity at the cellular level 21:19 – Stable rhythms: sleep, nourishment, hydration, movement 21:45 – Stillness, meditation, and parasympathetic repair 22:35 – Growth requires both resistance and recovery 24:44 – Connection, community, and loneliness as biological signals 25:27 – Eliminating fatal conveniences to restore vitality 26:02 – Your mitochondria are listening—change the signals 26:21 – Honoring Huberman & Picard's contribution to human health 27:12 – Energy flow as the foundation of a SuperLife 28:11 – Closing reflections and invitation to apply this work     Thank You to Our Sponsors Therasage: Go to www.therasage.com and use code DARIN at checkout for 15% off Caldera Lab: Experience the clinically proven benefits of Caldera Lab's clean skincare regimen and enjoy 20% off your order by visiting calderalab.com/darin and using code DARIN at checkout.     Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien     Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences     Key Takeaway "Your mitochondria are not broken. They are responding perfectly to the signals you give them. Change the signals, and your energy, resilience, and life will follow."     Bibliography & Sources Here is the bibliography based on the sources referenced in the document, formatted with direct links to the scientific papers, books, and the podcast episode. Primary Source Material Huberman, A. (Host). (2025, December 15). Improve Energy & Longevity by Optimizing Mitochondria with Dr. Martin Picard [Audio/Video podcast]. Huberman Lab. Link to Episode Picard Lab. Mitochondrial Psychobiology Group. Columbia University Irving Medical Center. Link to Lab Website Key Scientific Literature & Books Hood, D. A., Memme, J. M., Oliveira, A. N., & Triolo, M. (2019). Exercise and Mitochondrial Biogenesis. Physiological Reviews, 99(1), 669–715. Read Study Lane, N. (2015). The Vital Question: Energy, Evolution, and the Origins of Complex Life. W.W. Norton & Company. Book Link López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013). The Hallmarks of Aging. Cell, 153(6), 1194–1217. Read Study Mattson, M. P., Moehl, K., Ghena, N., Schmaedick, M., & Cheng, A. (2018). Intermittent Metabolic Switching, Neuroplasticity and Brain Health. Nature Reviews Neuroscience, 19, 63–80. Read Study Picard, M., & McEwen, B. S. (2018). Psychological Stress and Mitochondria: A Systematic Review. Psychosomatic Medicine, 80(2), 126–140. Read Study Picard, M., & Shirihai, O. S. (2022). Mitochondrial Psychobiology: Foundations and Applications. Current Opinion in Behavioral Sciences, 43, 102–110. Read Study Speakman, J. R., & Selman, C. (2011). The Free-Radical Damage Theory: Accumulating Evidence Against a Simple Link. Trends in Ecology & Evolution, 26(1), 33–39. Read Study Wallace, D. C. (2015). Mitochondria and Cancer. Nature Reviews Cancer, 12, 685–698. (Note: Often referenced alongside his Annual Review of Genetics work on aging). Read Study

Most conversations about longevity focus on tactics. This episode breaks down the biology underneath them. You'll hear a systems level analysis of how insulin signaling, mTOR, mitochondrial function, inflammation, and nutrient sensing interact to determine biological age, disease risk, and long term human performance. This is not surface level biohacking. It is a deep dive into the mechanisms that actually control aging, metabolism, muscle preservation, and brain optimization, and why most anti aging strategies fail when they ignore these foundations. This all-time classic episode from 2024, has host Dave Asprey joined by Mark Hyman, a practicing physician and one of the most respected leaders in functional medicine. Dr. Hyman is the founder and senior advisor of The UltraWellnessCenter, the founder and former head of strategy and innovation at the Cleveland Clinic Center for Functional Medicine, and a long time advocate for treating root causes instead of managing disease. With over 30 years of clinical experience, his work focuses on restoring mitochondrial health, optimizing metabolism, reversing chronic disease, and slowing biological aging using science backed interventions. Together, Dave and Mark dismantle common myths around protein, carnivore diets, ketosis, fasting, supplements, and longevity drugs. They explain why sugar accelerates aging faster than protein, how mTOR must cycle instead of staying suppressed, and why muscle, mitochondria, and metabolic flexibility matter more than calorie restriction. The conversation also covers nootropics, sleep optimization, neuroplasticity, AI driven diagnostics, and how functional medicine reframes aging as a reversible biological process rather than an inevitable decline. You'll learn: • How insulin and nutrient sensing control aging speed • Why mitochondria sit at the center of longevity and disease • The truth about mTOR, fasting, and protein intake • How ketosis and metabolic flexibility protect long term health • Where supplements and nootropics actually fit in brain optimization • Why functional medicine outperforms symptom based care • How AI and advanced testing are reshaping modern medicine Thank you to our sponsors! - MASA Chips | Go to https://www.masachips.com/DAVEASPREY and use code DAVEASPREY for 25% off your first order. -ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. -OneSkin | Try OneSkin for 15% off with code DAVE at https://www.oneskin.co/DAVE. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: longevity biohacking, functional medicine longevity, biological age reversal, mitochondria and aging, mTOR pathway aging, insulin resistance and aging, metabolic flexibility, fasting and longevity, ketosis and metabolism, protein intake and mTOR, muscle and longevity, inflammaging, chronic inflammation aging, mitochondrial dysfunction, nutrient sensing pathways, rapamycin longevity, metformin longevity debate, carnivore diet longevity, sugar and aging, brain optimization longevity, neuroplasticity and aging, sleep optimization biohacking, supplements for longevity, anti aging metabolism, human performance optimization, Dave Asprey longevity, Mark Hyman longevity Resources: • Mark's Website: https://drhyman.com/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 - Trailer 0:45 - Introduction 4:49 - Aging as a Treatable Disease 7:50 - The Hallmarks of Aging 14:23 - Nutrient Sensing and Longevity Switches 17:37 - Time Restricted Eating and Autophagy 20:44 - The Four Longevity Pathways 21:49 - Metformin Debate 25:30 - Ozempic and Weight Loss 28:42 - Rapamycin and mTOR 36:23 - Meat, Protein, and Aging 39:46 - Protein Quality and Muscle Synthesis 45:50 - Protein Timing for Muscle Building 48:08 - Metabolic Flexibility 51:32 - Inflammaging 55:26 - Zombie Cells and Senescence See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of Skin Anarchy, Dr. Ekta Yadav sits down with Smitha Rao—biotechnologist, longtime beauty innovator, and founder of Pareva Beauty—for a grounded, science-first conversation on what skin longevity actually means. Part of the Lessons in Longevity series, this episode challenges the tired idea of “anti-aging” and reframes skincare as long-term biological support rather than surface-level correction.With nearly two decades in biotech and beauty, Smitha brings a rare perspective shaped by molecule development, patents licensed across major brands, and leadership roles behind more than 200 products. That experience revealed a growing disconnect: while consumers want clarity and real science, the industry often defaults to hype, fear-based claims, and trend chasing. Pareva Beauty was born as a response—built on transparency, rigor, and the belief that longevity is about extending skin function and resilience, not reversing time.At the center of the discussion is Molecur 3™, Pareva's proprietary, plant-based technology inspired by the Hallmarks of Aging. Smitha explains how targeting inflammation, cellular stress, and age-related decline—rather than isolated “anti-aging” claims—creates a more realistic and sustainable path for skin health. The conversation also dives into plant-derived exosomal signaling, why it differs from human-derived systems, and how it offers a safer, scalable approach for topical longevity skincare.Together, Dr. Ekta and Smitha unpack why fewer, better-designed products outperform complex routines, why transparency matters more than vague “clean” labels, and how longevity skincare must earn trust through data—not promises.Listen to the full episode to hear how Smitha Rao is helping redefine the future of skincare—where science, honesty, and long-term skin health come first.Shop Parëva Beauty and use code SA20 for 20% through 3/17.CHAPTERS:(0:02) - Introduction, Lessons in Longevity & Smitha Rao(1:21) - From Biotech to Beauty Innovation(2:50) - Why Pareva Was Created & The Longevity Gap(3:33) - Defining Skin Longevity & Extending Your Prime(5:38) - Rejecting Anti-Aging & Reframing Aging Quality(8:51) - Molecure 3™: Hallmarks of Aging Inspiration(10:27) - Plant Stem Cells, NAD⁺ & Exosome Signaling(14:00) - Exosomes Explained: Plant vs Human-Derived(22:51) - Simplifying Skincare: Fewer Steps, Better ResultsPlease fill out this survey to give us feedback on the show!Don't forget to subscribe to Skin Anarchy on Apple Podcasts, Spotify, or your preferred platform.Reach out to us through email with any questions.Sign up for our newsletter!Shop all our episodes and products mentioned through our ShopMy Shelf!*This is a paid collaboration Hosted on Acast. See acast.com/privacy for more information.

In this episode of "Women of Impact," Lisa Bilyeu welcomes Dr. Orion Taraban, psychologist, YouTube creator, and author of the bestselling book "The Value of Others." Dr. Taraban brings a refreshingly candid — and sometimes controversial — perspective to the complex world of romantic relationships, power dynamics, and emotional safety. Together, they pull back the curtain on common traps women fall into, how to recognize manipulation (especially from narcissists or cluster B personalities), and the essential mindsets needed to reclaim your relationship power once and for all. Dr. Taraban and Lisa set the groundwork by tackling why no one can technically manipulate your emotions — unless you allow them to. This is essential listening for anyone looking to understand how to protect themselves while dating—or simply elevate their personal relationships to a new level of autonomy. In this episode: The Nature of Manipulation & Emotional Vulnerability Why “Poker Face” Tactics Matter for Safety Real-World Examples: DARVO & the Anatomy of Gaslighting The 10 Principles of Power: Who Really Holds the Cards? Women, Power, and the Unspoken Rules of Pursuit The Role of Optionality in Relationships Double Standards, Gendered Power, and Inequality Attraction, Fantasy, and the Dangers of Projecting Red Flags, Rationalizations & Why We Stay Cluster B Personalities and the Hallmarks of Narcissistic Abuse Thank you to our sponsors:  Macy's: Upgrade your glam at https://macys.com Vital Proteins: Get 20% off by going to https://www.vitalproteins.com and entering promo code WOI at check out. Found: Open a Found account for FREE at http://found.com True Classic: Discounts at https://trueclassic.com/WOI OneSkin: 15% off code LISA at https://oneskin.co Shopify: Sign up for your one-dollar-per-month trial period at https://shopify.com/lisa Magic Spoon: code LISABILYEU $5 off https://magicspoon.com/lisabilyeu Follow Dr. Orion Taraban: YouTube: https://www.youtube.com/@psychacks Website: https://oriontarabanpsyd.com/ FOLLOW LISA BILYEU: Instagram: ⁠https://www.instagram.com/lisabilyeu/⁠ YouTube: ⁠https://www.youtube.com/womenofimpact⁠ Tik Tok: ⁠https://www.tiktok.com/@lisa_bilyeu?lang=en Facebook: https://www.facebook.com/lisabilyeu Learn more about your ad choices. Visit megaphone.fm/adchoicesSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of "Women of Impact," Lisa Bilyeu welcomes Dr. Orion Taraban, psychologist, YouTube creator, and author of the bestselling book "The Value of Others." Dr. Taraban brings a refreshingly candid — and sometimes controversial — perspective to the complex world of romantic relationships, power dynamics, and emotional safety. Together, they pull back the curtain on common traps women fall into, how to recognize manipulation (especially from narcissists or cluster B personalities), and the essential mindsets needed to reclaim your relationship power once and for all. Dr. Taraban and Lisa set the groundwork by tackling why no one can technically manipulate your emotions — unless you allow them to. This is essential listening for anyone looking to understand how to protect themselves while dating—or simply elevate their personal relationships to a new level of autonomy. In this episode: The Nature of Manipulation & Emotional Vulnerability Why “Poker Face” Tactics Matter for Safety Real-World Examples: DARVO & the Anatomy of Gaslighting The 10 Principles of Power: Who Really Holds the Cards? Women, Power, and the Unspoken Rules of Pursuit The Role of Optionality in Relationships Double Standards, Gendered Power, and Inequality Attraction, Fantasy, and the Dangers of Projecting Red Flags, Rationalizations & Why We Stay Cluster B Personalities and the Hallmarks of Narcissistic Abuse Thank you to our sponsors:  Macy's: Upgrade your glam at https://macys.com Vital Proteins: Get 20% off by going to https://www.vitalproteins.com and entering promo code WOI at check out. Found: Open a Found account for FREE at http://found.com True Classic: Discounts at https://trueclassic.com/WOI OneSkin: 15% off code LISA at https://oneskin.co Shopify: Sign up for your one-dollar-per-month trial period at https://shopify.com/lisa Magic Spoon: code LISABILYEU $5 off https://magicspoon.com/lisabilyeu Follow Dr. Orion Taraban: YouTube: https://www.youtube.com/@psychacks Website: https://oriontarabanpsyd.com/ FOLLOW LISA BILYEU: Instagram: ⁠https://www.instagram.com/lisabilyeu/⁠ YouTube: ⁠https://www.youtube.com/womenofimpact⁠ Tik Tok: ⁠https://www.tiktok.com/@lisa_bilyeu?lang=en Facebook: https://www.facebook.com/lisabilyeu Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is sponsored by Flipping 50 Menopause Fitness Specialist. Become a health & fitness coach who finally speaks midlife women's language. Learn how to design workouts that balance hormones that actually get results for women in menopause. Other Episodes You Might Like: Previous Episode - Thyroid Health Next Episode - What's Still Missing from Women's Fitness Programs More Like This: What They Don't Teach Trainers About Exercise Prescription The ONE Thing Your Menopause Fitness Routine Is Missing Effects of Menopause Exercise on 12 Hallmarks of Aging Resources: Join Flipping 50 Menopause Fitness Specialist® to become a coach! Don't know where to start? Book your Discovery Call with Debra. Leave this session with insight into exactly what to do right now to make small changes, smart decisions about your exercise time and energy. Get the Exercise RX for Women Over 40 and master the programming variables that make or break results for women in midlife! Use Flipping 50 Scorecard & Guide to measure what matters with an easy at-home self-assessment test you can do in minutes. Women's fitness programs don't always tell the truth about what really works in menopause—and that's exactly why this episode matters.  If you've been working out harder, longer, or “like you used to” and still not seeing results, consider this your turning point.  Midlife fitness isn't about doing more—it's about doing what actually works with your hormones, your energy, and your real life.  Let's talk about how the right women's fitness programs can finally help you feel stronger, sleep deeper, tone faster, and love your workouts again.

Other Episodes You Might Like: Previous Episode - The Perimenopause Brain Health Window with Mariza Snyder Next Episode - Thyroid Health with McCall McPherson More Like This: Exercise Recovery After 40: Connective Tissue in Menopause Effects of Menopause Exercise on 12 Hallmarks of Aging 5 Things I Do When I Need a Reset or I've Had a Fitness Plateau Resources: Get the Flipping 50 STRONGER 12-week program for your at-home safe, sane, simple exercises. Join Flipping 50 Menopause Fitness Specialist® to become a coach! Don't know where to start? Book your Discovery Call with Debra. Leave this session with insight into exactly what to do right now to make small changes, smart decisions about your exercise time and energy. If you've been doing all the right things but still not seeing the results you deserve, this episode will show you exactly what your menopause fitness routine is missing. You're eating right, lifting weights, walking, and following all the “they say” advice — yet your metabolism, muscle tone, or energy still feels stuck. Today, I'm revealing the one game-changing ingredient most midlife women overlook. No… it's not another supplement, diet tweak, or fancy fitness app. You'll hear why your workouts may be quietly working against you. You'll understand why your menopause fitness routine is missing this essential piece — and how adding it back brings your energy, metabolism, and confidence roaring back.

In this episode VDH and Jack cover Trump's immigration policies and missing migrant children, Claudine Gay attacking her successor at Harvard, and the alarming parallels between modern America and ancient Rome.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Josh Spitalnick is a clinical and research psychologist with expertise in treating a variety of anxiety conditions with cognitive-behavioral therapy (CBT) and other evidence-based approaches. In this episode, Josh unpacks the four layers of anxiety—psychological, emotional, cognitive, and behavioral—highlighting why avoidance is the key feature that transforms ordinary worry into disorder. He explains why he continues to treat OCD and PTSD as anxiety conditions despite their DSM-5 reclassification, and he draws important distinctions between worries versus worrying and thoughts versus thinking. The discussion explores health anxiety, illness anxiety, and the impact of modern contributors such as wearables, social media, and the COVID era, while weaving in real-world case studies and Josh's structured assessment approach. Josh also breaks down evidence-based treatments, from exposure therapy and cognitive-behavioral therapy (CBT) to acceptance and commitment therapy (ACT), along with the role of medication, lifestyle factors, and how shifting from avoidance to committed action can build long-term resilience. We discuss: Josh's professional background and his holistic approach to treating anxiety [3:00]; Definition of anxiety and changes in the DSM-5 [5:00]; The psychological and cognitive aspects of anxiety [10:45]; Breaking down anxiety symptoms: triggers, fears, and hidden mental rituals [17:00]; Thoughts versus thinking and worries versus worrying: what constitutes dysfunction [20:15]; Health anxiety and the limits of medical reassurance: understanding illness anxiety and somatic symptom disorder [24:30]; Triggering events for health anxiety, symptom fixation, heritability, and the role of nature versus nurture [36:30]; Historical and modern shifts in health anxiety, from HIV/AIDS in the 1980s to today's heightened fears of cancer [45:30]; Modern factors and recent events that have amplified societal anxiety levels [47:15]; Josh's approach to patients with excessive health-related rituals and/or OCD using CBT and exposure therapy [54:30]; Hypothetical example of treating a person with a fear of flying: assessment, panic disorder, and the role of medication and exposure therapy [1:03:15]; The four types of exposure therapy and the shift from habituation to inhibitory learning [1:14:00]; Treating people with OCD that manifests in disturbing and intrusive thoughts, and why therapy focuses on values over reassurance [1:21:00]; Acceptance and commitment therapy (ACT): reorienting patients toward values-driven living rather than symptom elimination [1:31:45]; Mindfulness as a tool to cultivate presence, awareness, and healthy engagement with life [1:36:30]; Hallmarks of successful therapy and red-flags that therapy is not going well [1:38:15]; The relationship between anxiety and substance use, and the therapeutic challenges it creates [1:44:45]; Anxiety's overlap with ADHD, OCD, autism, and physical health conditions [1:49:45]; Debunking the harmful myth that health anxiety is a “made up” condition [1:51:30]; Prevalence, severity, and evolving treatments for health anxiety and OCD [1:54:45]; Treating health anxiety is about providing patients with skills to improve quality of life—a discussion on how to address symptoms often attributed to long COVID [2:01:30]; Balancing the benefits of abundant health information with the risks of fueling health anxiety [2:06:30]; Advice for finding a telehealth provider with expertise in health anxiety [2:11:00]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube