Modern Healthspan

Here Dr Tara Walker talks about the latest research on how exercise impacts the brain and what the best exercise forms are to protect your cognitive ability as you age.

Here Dr Thomas Levy talks about the amazing power of Vitamin C as an antioxidant with amazing beneficial capabilities. We also discuss the other supplements in his Top 8 for cellular and mitochondrial health

Here Sebastian talks about rejuvenating the immune system with HSC transplants, how this can be done and the benefits. He proposes a model of proactive immune system renewal. We then talk about LongBio & wider progress to rejuvenation therapeutics.

Here Dr Kidd talks about phosphatidylserine the benefits it provides as shown by RTCs. Although not approved, it even seems to have a blessing from the FDA.

Here Dr Holick talks about Vitamin D3, how much we need and why it is so important for the bone health and the immune system.

Here Liz talks about her personal experience with gene therapy and the innovations, the state of the industry and what the future holds. The therapies exist why is it so difficult to make them available!

Here Liam and Will from Neuronic talk about their red light devices, the cognitive benefits and science and why they chose to use 1070 nm red light.

Here Dave Pascoe talks about his exercise, experience with exosomes and stem cells and his systems for managing his data.

Here Dave Pascoe talks about his protocol and some of his philosophy behind it. The interview ran to two hours so I have split it into two parts.

Here Leslie Kenny talks about the benefits of spermidine and the science behind it, while also sharing her personal health journey

Here Dr Lanna talks about his work in rejuvenating the immune system by rescuing senescent T--cells.

Here Dr Dror talks about the investment market for Longevity, who are some of the major players, what they are investing in and how it is different this time.

Here Dr Jepsen talks about the work they are doing at Openwater, using a consumer technology focus to bring affordable precision solutions to healthcare with an open source approach. The potential for the platform that they are developing is amazing.

Here Dr Phillips talks about her system for overall oral healthcare, improving teeth, gums and the oral microbiome.

Here Dr Breus, the Sleep Doctor, talks about how sleep changes with aging and gives some advice on getting good quality sleep, using a sleep tracker and getting back to sleep after you wake up in the middle of the night.

Here we talk with Dr Adam Perlman the Chief Medical Officer of Pendulum Therapeutics about the microbiome and probiotics and their impact on metabolic health. We also look into the results from the clinical trials of the products

Here we talk with Dr Adam Perlman the Chief Medical Officer of Pendulum Therapeutics about the microbiome and probiotics and their impact on metabolic health. We also look into the results from the clinical trials of the products.

Here we talk with Professor Mark Tarnopolsky from McMaster University about mitochondria, what goes wrong with them in aging and how to he has used a multi-supplement approach to improve their function in aging and in case of disease.

Here we talk with Don Moxley of Stemregen about how stem cells are critical for recovery and so determine your ability to train and positively adapt. We also discuss the new sport science function that he is setting up at Stemregen and using HRV in training.

Here we talk with Dr Bill Andrews all about telomeres, why they are on the critical path of aging and finding a way to lengthen them is required in an complete longevity solution.

Here we talk with Dr Shai Efrati about HBOT, Hyperbaric Oxygen Therapy and his protocol. It is counterintuitive but the mechanism is through the activation of HIF via hypoxia!

Here we talk with Dr Mitchell Clionsky, co-author of Dementia Prevention : Using Your Head to Save Your Brain, about strategies to prevent or delay the onset of dementia. Dr Clionsky discusses that the current scientific thinking is that 50% of dementia could be avoided through lifestyle factors.

Here we talk with Dr Paul Chazot of Durham University in the UK about the remarkable results he is seeing in using redlight therapy to address various dementias. And of course we get into the details of how it works and what the parameters of the light used are.

DESCRIPTION Here we talk with Dr Stephanie Venn-Watson about C15, an odd-chain saturated fatty acid which has been shown to have benefits in cellular health and is correlated with better metabolic health.

Here we talk with Dr Andrea Maier of NUS about the work she is doing in rethinking longevity therapies and how they can be delivered. We talk about some of the supplements such as AKG and NMN that they are trialing.

DESCRIPTION Here we talk with Tom Benson, CEO of Mitrix about mitochondrial transplantation to replace your old damaged mitochondria with new ones so that they can get back to full energy producing mode. His aim is to start a trial targeting to get the participants to live to 130.

Here we talk Christian Drapeau founder of Stemregen about the wonders of stem cells. We dive into the science of what they are, how they work to repair the body and how we can mobilize them to help us remain healthy.

Apologies for the delay in releasing this. Should be more regular in the future! DESCRIPTION Here we talk with Dr Torkil Færø the author of the Pulse Cure about what HRV is, how it is linked to health and how we can use it to improve our longevity protocol

Here we talk with Dr Steve Simpson and Dave Raubenheimer about their concept of Nutritional Geometry and how this helps to think about the optimal macro and micro nutrient mix. Of particular note is Protein Leverage, the idea that humans will eat until we have had sufficient protein.

Here we talk with Professor Ellen Langer of Harvard University about her research and her latest book, The Mindful Body : Thinking Our Way To Chronic Health. The mind and body are one and we can control the body with the mind.

Here we talk with Dr William Li about how food can be medicine, both in a preventative and a therapeutic way. We focus mostly on stem cell activation and preservation and also look at angiogenesis - building new blood vessels.

Here we talk with Dr Glen Jeffery from University College London about how red light energizes your mitochondria and some of the amazing benefits of this. We also discuss some of the detrimental effects of blue light.

DESCRIPTION Here we talk with Dr Diogo Barardo, who is head of research and development at NOVOS, about NOVOS Vital, a supplement which comes in a gummie form and have a catch-up on other activities at NOVOS.

DESCRIPTION Dr. Greg Fahy is a world renowned cryobiologist and is also the chief science officer, and co-founder, of Intervene Immune, a company which pioneers treatments for thymus regeneration and age-related immune system decline. Dr. Fahy Designed and led the pilot TRIIM trial which first time showing both thymus rejuvenation and reversal of human epigenetic age. We talk to him about the results to the TRIIM follow up trial, TRIIM-XA, further trials in the works and plans for getting the TRIIM protocol into the clinic.

Description Hi all, apologies for the erratic release schedule recently. We have now changed the way that we release interviews on our YouTube channel and from now on will post the whole interview in a single video. The podcasts will follow the same pattern. This will mean that we have fewer, though longer podcasts. I hope that this works for you all. Thanks Richard Dr Keirstead talks about his work with stem cells and using the factors that young stem cells secrete to rejuvenate the immune system which then has systemic effects across the whole body. Dr Keirstead's therapy is currently in phase 1/2a human trials. Some links are affiliate links so we will earn a commission when they are used to purchase products.

Hi all, apologies for the erratic release schedule recently. We have now changed the way that we release interviews on our YouTube channel and from now on will post the whole interview in a single video. The podcasts will follow the same pattern. This will mean that we have fewer, though longer podcasts. I hope that this works for you all. Thanks Richard Dr. Bryan was the first to describe nitrite and nitrate as indispensable nutrients required for optimal cardiovascular health. He was the first to demonstrate and discover an endocrine function of nitric oxide via the formation of S-nitrosoglutathione and inorganic nitrite. Through the drug discovery program in natural product chemistry, Dr. Bryan discovered unique compositions of matter than can be used to safely and effectively generate and restore nitric oxide in humans. This technology is now validated in six published clinical trials. He is also a successful entrepreneur who has commercialized his nitric oxide technology through the formation of Human, to the Power of N, Inc (formerly Neogenis Labs) where he is a Founder and inventor. Dr. Bryan has been involved in nitric oxide research for the past 18 years and has made many seminal discoveries in the field. These discoveries and findings have transformed the development of safe and effective functional bioactive natural products in the treatment and prevention of human disease and may provide the basis for new preventive or therapeutic strategies in many chronic diseases. Dr. Bryan has published a number of highly cited papers and authored or edited 5 books. He is an international leader in molecular medicine and nitric oxide biochemistry. Dr Bryan talks about why nitric oxide is so essential to our health and longevity. It is well known as a vasodilator which helps with CVD risk but it also impacts dementia and metabolic syndrome.

Here Dr Reis talks about what causes aging of the skin, and UVB is one of the main causes and what her longevity protocol looks like. Dr. Carolina Reis is the co-found and CEO of OneSkin Technologies. She holds a biochemistry degree and a Ph.D. focused on stem cell and tissue engineering. After more than 10 years of developing science in academia, she is thrilled to translate basic science into products that will extend our healthspan. As a founder of OneSkin, she and the team have been working to develop the first anti-senescence topical product designed to promote skin health from within. Dr. Reis is an alumnus of IndieBio, the world's largest seed biotech accelerator. She has moved from Latin America to Silicon Valley 4 years ago to found OneSkin and has been actively engaged in the longevity ecosystem in the Bay Area.

Here Dr Reis talks about some of the customer feedback that they have received. The feedback is available at the bottom of the product pages on the OneSkin website. Dr. Carolina Reis is the co-found and CEO of OneSkin Technologies. She holds a biochemistry degree and a Ph.D. focused on stem cell and tissue engineering. After more than 10 years of developing science in academia, she is thrilled to translate basic science into products that will extend our healthspan. As a founder of OneSkin, she and the team have been working to develop the first anti-senescence topical product designed to promote skin health from within. Dr. Reis is an alumnus of IndieBio, the world's largest seed biotech accelerator. She has moved from Latin America to Silicon Valley 4 years ago to found OneSkin and has been actively engaged in the longevity ecosystem in the Bay Area.

Here Dr Reis talks about the human as well as in vitro trials that her company is doing. The papers can be found on the OneSkin website (including the one that she refers to in the video as being published in the next week) Dr. Carolina Reis is the co-found and CEO of OneSkin Technologies. She holds a biochemistry degree and a Ph.D. focused on stem cell and tissue engineering. After more than 10 years of developing science in academia, she is thrilled to translate basic science into products that will extend our healthspan. As a founder of OneSkin, she and the team have been working to develop the first anti-senescence topical product designed to promote skin health from within. Dr. Reis is an alumnus of IndieBio, the world's largest seed biotech accelerator. She has moved from Latin America to Silicon Valley 4 years ago to found OneSkin and has been actively engaged in the longevity ecosystem in the Bay Area.

Here Dr Reis talks about the new series of products that the team at OneSkin have developed, including for body, eyes, sun protection and a cleanser. Dr. Carolina Reis is the co-found and CEO of OneSkin Technologies. She holds a biochemistry degree and a Ph.D. focused on stem cell and tissue engineering. After more than 10 years of developing science in academia, she is thrilled to translate basic science into products that will extend our healthspan. As a founder of OneSkin, she and the team have been working to develop the first anti-senescence topical product designed to promote skin health from within. Dr. Reis is an alumnus of IndieBio, the world's largest seed biotech accelerator. She has moved from Latin America to Silicon Valley 4 years ago to found OneSkin and has been actively engaged in the longevity ecosystem in the Bay Area.

Here Dr Reis talks about the development of OS-1 the peptide used in One Skins products, its senomorphic effects and other ingredients which are included in the One Skin product range. Dr. Carolina Reis is the co-found and CEO of OneSkin Technologies. She holds a biochemistry degree and a Ph.D. focused on stem cell and tissue engineering. After more than 10 years of developing science in academia, she is thrilled to translate basic science into products that will extend our healthspan. As a founder of OneSkin, she and the team have been working to develop the first anti-senescence topical product designed to promote skin health from within. Dr. Reis is an alumnus of IndieBio, the world's largest seed biotech accelerator. She has moved from Latin America to Silicon Valley 4 years ago to found OneSkin and has been actively engaged in the longevity ecosystem in the Bay Area.

Here Dr Trommelen talks about practical take aways from his study. How much protein should we eat, how often and what type is best. He also talks about his personal protocol.

Here Dr Trommelen talks about how the MPS continues for more than 12 hours, because of the presence of amino acids in the blood, however, mTOR does not appear to be activated and autophagy is not suppressed and provides his explanation for these findings.

Here Dr Trommelen talks about the amount of protein required to initiate MPS, what muscle break down is and how MPS is measured. Key take away: It is muscle synthesis which determines muscle mass much more then breakdown as breakdown remains in a very tight range.

Here Dr Trommelen talks about exercise and protein and how they are related to muscle protein synthesis. The importance of having both, the time window for MPS and the training stimuli required.

Here Dr Trommelen talks about the background to the study, the major results and the type of protein used.

Here Dr Joffrey discusses Medicine 3.0 - how you can take control of your own health and his top 10 supplements (and three drugs) for longevity.

Here Dr Joffrey discusses sleep, how important it is and some tips for getting the best sleep.

Here Dr Joffrey discusses exercise for longevity and how it is different from exercise for other purposes including what is the minimum effective dose. He also talks about cardiovascular disease and why we should not die from it.

Here Dr Joffrey discusses the keys to a healthy diet. Time restricted feeding, controlling glucose in general and spikes in particular, and ensuring that you have sufficient protein.

Here Dr Joffrey discusses his view on future of aging and the most promising technology that he sees which will make a difference. He also talks about Longevity Escape Velocity.