Modern Healthspan

DESCRIPTIONNeuroscience professor Dr. Glen Jeffery from UCL reveals how LED lighting's blue light spike damages mitochondria, accelerates aging, and contributes to diabetes - while explaining simple solutions using red light therapy and incandescent bulbs to protect your health.Neuroscience professor Dr. Glen Jeffery from UCL reveals how LED lighting's blue light spike damages mitochondria, accelerates aging, and contributes to diabetes - while explaining simple solutions using red light therapy and incandescent bulbs to protect your health.

Discover why muscle power—not just strength—is the key predictor of healthy aging and longevity. Exercise physiologist Dr. Stuart Phillips reveals groundbreaking research showing that older adults can safely engage in power training, challenging decades of conventional wisdom about senior fitness.In this interview renowned exercise physiologist and gerontology expert Dr. Stuart Phillips from McMaster University shares cutting-edge insights into optimizing exercise and nutrition for healthy aging. Dr. Phillips, who has spent decades researching muscle physiology and aging, breaks down the science behind successful aging and reveals why most people are focusing on the wrong metrics.

Revolutionary brain health breakthrough: Light therapy helmet shows remarkable results for memory loss and cognitive enhancement. Real patient stories reveal dramatic improvements in speech, balance, and memory function using photobiomodulation technology.n this comprehensive interview with Liam, co-founder of Neuronic, we explore the cutting-edge world of photobiomodulation therapy for brain health. Discover how their light therapy devices - resembling bike helmets with 300+ LEDs - are helping patients with Alzheimer's, stroke, concussion, and long COVID brain fog. Liam shares incredible patient testimonials, including families saying "I got my mother back" and "I got my dad back" after just weeks of treatment. We dive deep into the science behind 1070 nanometer light therapy, discuss ongoing clinical trials, the FDA approval process, and how this technology is being used in clinics worldwide. Whether you're dealing with cognitive decline, seeking peak performance, or interested in preventive brain health, this episode reveals how light therapy could be a game-changer for neurological wellness.

Discover why the standard B12 test might be missing your deficiency, and learn the better biomarkers that could reveal if brain fog, fatigue, and cognitive decline are actually nutrition-related rather than age-related.In this deep dive with Dr. Martin Warren, Chief Scientific Officer at the Quadrum Institute and leading B12 researcher, we explore why vitamin B12 deficiency is far more common and complex than most people realize. Dr. Warren explains why standard B12 blood tests are unreliable (with only 50/50 accuracy for detecting deficiency), why the current deficiency cutoff of 148 picomolar may be too low, and how homocysteine and methylmalonic acid are better indicators of functional B12 status. He reveals that B12 deficiency can masquerade as normal aging—causing brain fog, fatigue, and cognitive decline—but is often reversible with proper treatment. The discussion covers why plant-based diets create deficiency risks, how absorption changes with age due to intrinsic factor decline, the connection between B12 and brain health (including white matter damage), and practical testing and supplementation strategies. Dr. Warren also makes a compelling case for revolutionizing healthcare through regular micronutrient monitoring rather than waiting for disease symptoms to appear.

Dr. Nathan Bryan, the world's leading nitric oxide researcher, reveals how this simple molecule could be the key to preventing and reversing Alzheimer's disease, heart disease, and diabetes. He explains why nitric oxide drops by 80% after age 60 and shares practical solutions including his revolutionary lozenge technology.In this comprehensive interview, Dr. Nathan Bryan, founder of Bryan Therapeutics and author of "The Secret of Nitric Oxide," breaks down decades of groundbreaking research on nitric oxide's role in human health. Dr. Bryan explains how nitric oxide functions as both a vasodilator and hormone, controlling blood flow, immune function, stem cell mobilization, and cellular energy production.Key topics covered include:Why nitric oxide production declines dramatically with age (down to 20% by age 60)The two pathways your body uses to produce nitric oxide and what disrupts themHow mouthwash, antacids, and poor diet destroy nitric oxide productionThe connection between nitric oxide deficiency and Alzheimer's, heart disease, and diabetesDr. Bryan's innovative lozenge technology that produces nitric oxide directly in the mouthPractical lifestyle strategies: intermittent fasting, avoiding sugar, tongue scraping, and dietary choicesFuture drug therapies in development for Alzheimer's, heart disease, and wound healingDr. Bryan presents compelling evidence that nitric oxide deficiency is the root cause of most age-related diseases and offers hope for prevention and reversal through targeted supplementation and lifestyle modifications.

Revolutionary brain health breakthrough: Light therapy helmet shows remarkable results for memory loss and cognitive enhancement. Real patient stories reveal dramatic improvements in speech, balance, and memory function using photobiomodulation technology.In this comprehensive interview with Liam, co-founder of Neuronic, we explore the cutting-edge world of photobiomodulation therapy for brain health. Discover how their light therapy devices - resembling bike helmets with 300+ LEDs - are helping patients with Alzheimer's, stroke, concussion, and long COVID brain fog. Liam shares incredible patient testimonials, including families saying "I got my mother back" and "I got my dad back" after just weeks of treatment. We dive deep into the science behind 1070 nanometer light therapy, discuss ongoing clinical trials, the FDA approval process, and how this technology is being used in clinics worldwide. Whether you're dealing with cognitive decline, seeking peak performance, or interested in preventive brain health, this episode reveals how light therapy could be a game-changer for neurological wellness.

Vitamin A is essential for brain health, but are you getting the right amount? In this interview with Dr. Peter McCaffery (University of Aberdeen), we explore vitamin A's critical role in memory, Alzheimer's risk, and why blood tests fail to detect deficiency or toxicity. Learn how to optimize your levels—without risking overconsumption from liver or supplements.

In this eye-opening interview, board-certified psychiatrist and nutritional psychiatry expert Dr. Drew Ramsey reveals the 9 essential tenets of mental fitness from his new book, Healing the Modern Brain. Learn how to optimize your brain health, prevent dementia, and build resilience with actionable habits backed by neuroscience—from nutrition and sleep hacks to combating isolation and trauma.

Benji explains how Pump Science leverages blockchain and cryptocurrency to revolutionize the search for longevity supplements. By using an automated, standardized process, Pump Science efficiently funds research and collects robust data to accelerate the discovery and validation of effective supplements for extending healthspan

Here Dr Ryan Rossner of Minicircle talks about plasmid gene therapy. We get into what it is, how it works, why it is simpler than viral vector gene therapy and look at some of the results that they have seen.

Here Dr Ben Lynch, author of Dirty Genes talks about what SNPs are, how they effect us but also why they do not define our destiny and what we can do about them. We dive into detail on histamine intolerance.

Here Michael Bush, talks about how to identify what probiotics could be helpful to you and how to identify ones that will work. We also look at the future where there are probiotics protecting you from kidney stones and producing GABA to make you less stressed!

DESCRIPTIONHere Dave Watumull of AX3 Life takes us through the amazing properties of astaxanthin. It is a powerful antioxidant and anti-inflammatory and the only supplement to show a greater than 10% increase in lifespan in the ITP trials. Here we dive into the chemistry, trial results and benefits of the molecule

In this video, I interview Dr Ross Walker a leading cardiologist with 40 years' experience and Consultant Cardiologist & Chairperson of Gut Foundation Australia. We talk about the importance of our microbiome, how it has such a large impact on many areas of our physical and mental health and what we can do to improve it.Links in this video:The Gut Foundation of Australia https://gutfoundation.com.au/*Thanks to our Sponsor*Theronomic by Wellizen. www.theronomic.com

Here Dr Joy Kong talks about stem cells, their amazing properties and how they can be used in medicine.

Here Dr Michael Lustgarten from Conquer Age or Die Trying talks about the approach that has put him head of the leader board on the Longevity World Cup. We also dive into aging clocks, rapamycin and upcoming technologies.

In this video, I interview Greg Macpherson, founder of SRW Laboratories, about their revolutionary supplement system, Cel System. Developed to address the hallmarks of ageing, SRW Laboratories have recently been published in the Aging Journal US (https://www.aging-us.com/article/206221/text), demonstrating measures to show reversal in biological age with clinical study participants. Greg explains the core principles behind their supplements and how they target the fundamental processes of ageing to potentially improve healthspan. Tune in to learn about this exciting development in the field of longevity science!Links in this video:SRW Laboratories Web site https://scienceresearchwellness.coEffects of a natural ingredients-based intervention targeting the hallmarks of ageing on epigenetic clocks, physical function, and body composition: a single-arm clinical trial https://www.aging-us.com/article/206221/text*Thanks to our Sponsor*SRW Laboratories https://scienceresearchwellness.co

Here Dr Robbins discusses what are the active factors in exosomes which help them to work their magic and cause systemic rejuvenation. This is the next step to making a reproducible therapy.

Here Ariel Garten introduces the new Muse S Athena with added near infrared light sensors and how these detect blood flow in the brain to determine how hard it is working. She also talks about new features in the app for sleep tracking and monitoring alpha waves.

Here Dr Tara Walker talks about the latest research on how exercise impacts the brain and what the best exercise forms are to protect your cognitive ability as you age.

Here Dr Thomas Levy talks about the amazing power of Vitamin C as an antioxidant with amazing beneficial capabilities. We also discuss the other supplements in his Top 8 for cellular and mitochondrial health

Here Sebastian talks about rejuvenating the immune system with HSC transplants, how this can be done and the benefits. He proposes a model of proactive immune system renewal. We then talk about LongBio & wider progress to rejuvenation therapeutics.

Here Dr Kidd talks about phosphatidylserine the benefits it provides as shown by RTCs. Although not approved, it even seems to have a blessing from the FDA.

Here Dr Holick talks about Vitamin D3, how much we need and why it is so important for the bone health and the immune system.

Here Liz talks about her personal experience with gene therapy and the innovations, the state of the industry and what the future holds. The therapies exist why is it so difficult to make them available!

Here Liam and Will from Neuronic talk about their red light devices, the cognitive benefits and science and why they chose to use 1070 nm red light.

Here Dave Pascoe talks about his exercise, experience with exosomes and stem cells and his systems for managing his data.

Here Dave Pascoe talks about his protocol and some of his philosophy behind it. The interview ran to two hours so I have split it into two parts.

Here Leslie Kenny talks about the benefits of spermidine and the science behind it, while also sharing her personal health journey

Here Dr Lanna talks about his work in rejuvenating the immune system by rescuing senescent T--cells.

Here Dr Dror talks about the investment market for Longevity, who are some of the major players, what they are investing in and how it is different this time.

Here Dr Jepsen talks about the work they are doing at Openwater, using a consumer technology focus to bring affordable precision solutions to healthcare with an open source approach. The potential for the platform that they are developing is amazing.

Here Dr Phillips talks about her system for overall oral healthcare, improving teeth, gums and the oral microbiome.

Here Dr Breus, the Sleep Doctor, talks about how sleep changes with aging and gives some advice on getting good quality sleep, using a sleep tracker and getting back to sleep after you wake up in the middle of the night.

Here we talk with Dr Adam Perlman the Chief Medical Officer of Pendulum Therapeutics about the microbiome and probiotics and their impact on metabolic health. We also look into the results from the clinical trials of the products

Here we talk with Dr Adam Perlman the Chief Medical Officer of Pendulum Therapeutics about the microbiome and probiotics and their impact on metabolic health. We also look into the results from the clinical trials of the products.

Here we talk with Professor Mark Tarnopolsky from McMaster University about mitochondria, what goes wrong with them in aging and how to he has used a multi-supplement approach to improve their function in aging and in case of disease.

Here we talk with Don Moxley of Stemregen about how stem cells are critical for recovery and so determine your ability to train and positively adapt. We also discuss the new sport science function that he is setting up at Stemregen and using HRV in training.

Here we talk with Dr Bill Andrews all about telomeres, why they are on the critical path of aging and finding a way to lengthen them is required in an complete longevity solution.

Here we talk with Dr Shai Efrati about HBOT, Hyperbaric Oxygen Therapy and his protocol. It is counterintuitive but the mechanism is through the activation of HIF via hypoxia!

Here we talk with Dr Mitchell Clionsky, co-author of Dementia Prevention : Using Your Head to Save Your Brain, about strategies to prevent or delay the onset of dementia. Dr Clionsky discusses that the current scientific thinking is that 50% of dementia could be avoided through lifestyle factors.

Here we talk with Dr Paul Chazot of Durham University in the UK about the remarkable results he is seeing in using redlight therapy to address various dementias. And of course we get into the details of how it works and what the parameters of the light used are.

DESCRIPTION Here we talk with Dr Stephanie Venn-Watson about C15, an odd-chain saturated fatty acid which has been shown to have benefits in cellular health and is correlated with better metabolic health.

Here we talk with Dr Andrea Maier of NUS about the work she is doing in rethinking longevity therapies and how they can be delivered. We talk about some of the supplements such as AKG and NMN that they are trialing.

DESCRIPTION Here we talk with Tom Benson, CEO of Mitrix about mitochondrial transplantation to replace your old damaged mitochondria with new ones so that they can get back to full energy producing mode. His aim is to start a trial targeting to get the participants to live to 130.

Here we talk Christian Drapeau founder of Stemregen about the wonders of stem cells. We dive into the science of what they are, how they work to repair the body and how we can mobilize them to help us remain healthy.

Apologies for the delay in releasing this. Should be more regular in the future! DESCRIPTION Here we talk with Dr Torkil Færø the author of the Pulse Cure about what HRV is, how it is linked to health and how we can use it to improve our longevity protocol

Here we talk with Dr Steve Simpson and Dave Raubenheimer about their concept of Nutritional Geometry and how this helps to think about the optimal macro and micro nutrient mix. Of particular note is Protein Leverage, the idea that humans will eat until we have had sufficient protein.

Here we talk with Professor Ellen Langer of Harvard University about her research and her latest book, The Mindful Body : Thinking Our Way To Chronic Health. The mind and body are one and we can control the body with the mind.

Here we talk with Dr William Li about how food can be medicine, both in a preventative and a therapeutic way. We focus mostly on stem cell activation and preservation and also look at angiogenesis - building new blood vessels.

Here we talk with Dr Glen Jeffery from University College London about how red light energizes your mitochondria and some of the amazing benefits of this. We also discuss some of the detrimental effects of blue light.