Podcasts about metabolic research

Is obesity a choice or a disease? Join experts in obesity Dr Robert Kushner (Professor of Medicine at Northwestern Feinberg School of Medicine and Director of the Center for Lifestyle Medicine at Northwestern Medicine, in Chicago), Dr Louis Aronne (Professor of Metabolic Research and Director of the Comprehensive Weight Control Center, in the Division of Diabetes, Endocrinology and Metabolism at Weill Cornell Medicine, in New York City), and Dr Jamy Ard (Professor of Epidemiology and Prevention at Wake Forest School of Medicine and Co-Director of the Wake Forest Baptist Health Weight Management Center) as they raise awareness about obesity as a chronic, progressive disease with biological and environmental components. The podcast will focus on how obesity is misunderstood and often stigmatized as a choice or a lack of willpower instead of a disease; and where lack of education and bias can lead to underdiagnosis and under management of obesity. The panel will also discuss the weight-related comorbidities, such as cardiometabolic multimorbidities, and will share tips on how to engage your patients with obesity to start thinking about their weight management journey.  This program is intended for clinicians. The information presented is aligned with the views and opinions of the speakers and is sponsored by Novo Nordisk. This podcast is not to be used as medical advice and is intended for educational purposes only.  Faculty Presenters:  Robert Kushner, MD Professor, Departments of Medicine and Medical Education Northwestern University Feinberg School of Medicine Chicago, IL  Jamy Ard, MD Professor Wake Forest School of Medicine Winston-Salem, NC  Louis Aronne, MD, FACP, DABOM Sanford I. Weill Professor of Metabolic Research New York, NY 

Host: John Buse, MD, PhD Guest: Louis J. Aronne, MD, FTOS In the SURMOUNT-4 trial, 100 patients with obesity were on tirezpatide for 9 months, and the average weight loss was 20.9 percent. The patients were then randomized to receive either placebo with behavioral intervention or tirzepatide for another year, and the patients in the former group regained a significant amount of weight. Dive further into the study's findings and implications with Dr. John Buse and Dr. Louis Aronne, the Sanford I. Weill Professor of Metabolic Research at Weill Cornell Medical College in New York.

Polycystic ovary syndrome (PCOS) is a common condition impacting roughly one in four women of reproductive age. , In this show we discuss natural ways to reverse the underlying factors driving PCOS.  Save 15% OFF on Berberine HCl and Myo-Inositol containing Sleep Formulations from MYOXCIENCE Save with code podcast at checkout  Links to Studies, Images and the Video Version: https://bit.ly/3nMt9QJ Time Stamps 00:04 PCOS (polycystic ovarian syndrome) is about 1 in 5 of women of childbearing age. 00:26 The root cause of PCOS is poor metabolic health. 01:54 Ovaries hyper secrete androgens that are linked with challenges within the ovaries and the formation of water-forming cysts. 02:39 Hormonal birth control is frequently prescribed to increase sex hormone binding globulin and neutralize the elevated androgens. 04:04 Some cytochrome P450 enzymes are involved in the formation of steroid-like hormones, like testosterone. 05:04 Insulin and IGF-1 increase the activity of a cytochrome P450 enzyme called CYP17A1, which then increases testosterone, dihydrotestosterone, and DHEA within the ovaries. 06:36 Excessive levels of androgens cause hair loss, infertility, lack of ovulation, and cause the formation of water forming cysts within the ovaries. 08:24 Autoimmunity often co-occurs with PCOS. 08:44 Deliberate cold exposure helps metabolic health by stimulating brown and beige fat cells. 09:54 Metabolic health increases the activity of enzymes that create hormones. It does the inverse in men and women. 10:04 Men's poor metabolic health drives the formation of extra estrogen. 10:14 Women's poor metabolic health drives the formation of extra testosterone. 12:44 97% of obese women have PCOS. 65% of non-obese women have PCOS. 13:14 Fat cells secrete hormones, called adipocytokines. One of these is leptin. 13:54 Leptin decreases activity of T-regulatory cells that help to prevent autoimmunity. 16:04 Belly fat cells convert androgens into estrogens. This is impacted by insulin. 18:14 Nutrition and exercise are fundamental ways to address poor metabolic health. 18:24 A ketogenic or low carb diet is helpful because it manages blood sugar and insulin, and ketones have immune signaling properties. 19:24 Intermittent fasting can support glycemic variability and improve insulin sensitivity. 19:46 Time restricted feeding with a 16 or 18 hour fast is also helpful for longevity, burning fat, and supporting metabolic health. 20:14 Poor sleep exacerbates insulin resistance. Tape your mouth shut when you sleep. 21:24 Resistance training decreases androgens in women with PCOS. All exercise supports underlying metabolic dysfunction. 22:24 Magnesium is helpful for supporting insulin sensitivity. 23:15 Myo-inositol and inositol makes ovaries more sensitive to insulin, preventing the increase in androgens. 24:04 Vitamin D is involved in blood sugar regulation, immune health, and sleep quality. 24:19 Gut health is important to metabolic health. Eat real food and ferments. 24:54 Berberine hydrochloride, 500 mg 1 to 3 times per day, is a natural Metformin. Studies Mentioned Witchel, S. F., & Plant, T. M. (2020). Intertwined reproductive endocrinology: Puberty and polycystic ovary syndrome. Current Opinion in Endocrine and Metabolic Research, 14, 127–136. http://doi.org/10.1016/j.coemr.2020.07.004 Stefanaki, C., Bacopoulou, F., Kandaraki, E., Boschiero, D., & Diamandi-Kandarakis, E. (2019). Lean Women on Metformin and Oral Contraceptives for Polycystic Ovary Syndrome Demonstrate a Dehydrated Osteosarcopenic Phenotype: A Pilot Study. Nutrients, 11(9), 2055. http://doi.org/10.3390/nu11092055 Moghetti, P., & Tosi, F. (2020). Insulin resistance and PCOS: chicken or egg? Journal of Endocrinological Investigation, 44(2), 233–244. http://doi.org/10.1007/s40618-020-01351-0 Scarfò, G., Daniele, S., Fusi, J., Gesi, M., Martini, C., Franzoni, F., et al. (2022). Metabolic and Molecular Mechanisms of Diet and Physical Exercise in the Management of Polycystic Ovarian Syndrome. Biomedicines, 10(6), 1305. http://doi.org/10.3390/biomedicines10061305 Witchel, S. F., & Plant, T. M. (2020). Intertwined reproductive endocrinology: Puberty and polycystic ovary syndrome. Current Opinion in Endocrine and Metabolic Research, 14, 127–136. http://doi.org/10.1016/j.coemr.2020.07.004 Optimal management of polycystic ovary syndrome in adolescence. (2015). Optimal management of polycystic ovary syndrome in adolescence, 1–8. http://doi.org/10.1136/archdischild-2014-306471&domain=pdf&date_stamp=2015-06-22

In the first episode of season 3, Bea talks about diabetes and obesity to Professor Jens Brüning, a Director of the Max Planck Institute for Metabolic Research in Cologne, as well as head of the clinic for Endocrinology, Diabetes and Preventive Medicine at the University Hospital in Cologne. About 10% of the people worldwide have diabetes and it is one of the leading causes of death in the world, with its prevalence steadily increasing over the past few decades. Bea and Jens talk about the diabetes epidemic and the link between diabetes and obesity. Jens explains the two types of diabetes, the function of insulin, ghrelin, and leptin, and the role genetics and lifestyle play in diabetes and obesity. He also clarifies pre-diabetes and gestational diabetes, and sheds some light onto the connection between diabetes and COVID-19. Jens emphasises the importance of sports for metabolism, in general, and in diabetes, in particular. The two also discuss how realistic the plans for a miracle pill that could replace sports are and the importance of eating with your circadian rhythm. Professor Brüning's lab: https://www.sf.mpg.de/research/bruening Max Planck Institute for Metabolic Research: https://www.sf.mpg.de/en Facts in the description from: https://www.who.int/health-topics/diabetes Episode Art: Photo by Towfiqu barbhuiya (https://unsplash.com/@towfiqu999999) on Unsplash (https://unsplash.com/) You can follow us on: Twitter: https://twitter.com/MPPhdnetPodcast Instagram: https://www.instagram.com/offspringmagazine_thepodcast Linkedin: https://www.linkedin.com/company/offspring-magazine-the-podcast YouTube: https://youtube.com/c/MaxPlanckPhDnet If you have any feedback, comments or suggestions, reach out to us at offspring.podcasts@phdnet.mpg.de Check out the Offspring-Blog where we publish articles on a regular basis: https://www.phdnet.mpg.de/offspring-blog Intro - Outro music composed by Srinath Ramkumar: https://twitter.com/srinathramkumar Pre-Intro jingle composed by Gustavo Carrizo: https://www.instagram.com/carrizo.gus See you soon!

Dr. Benjamin Bikman is a research scientist who focuses on metabolic research and insulin resistance.  Dr. Benjamin is also a published author and associate professor at Brigham Young University (BYU). He conducts research on metabolic disorders like obesity, The post 892: How to Break Into Metabolic Research With Dr. Benjamin Bikman, Brigham Young University [Espresso Shots] appeared first on Time4Coffee.

Dr. Benjamin Bikman is a metabolic scientist who primarily researches insulin resistance. Benjamin is also a published author and associate professor at Brigham Young University (BYU). The post 837: What Metabolic Research Looks Like With Dr. Benjamin Bikman, Brigham Young University [K-Cup TripleShot] appeared first on Time4Coffee.

We’d love to hear from you (feedback@breakingbadscience.com)Look us up on social media Facebook: https://www.facebook.com/groups/385282925919540Instagram: https://www.instagram.com/breakingbadsciencepodcast/Website: http://www.breakingbadscience.com/Patreon: https://www.patreon.com/breakingbadscienceEvery week we look at a new scientific concept and delve into the science behind it. How do we go about that? What does it take to look at information that someone presents and evaluate its quality? Join hosts Shanti and Danny as we dive into Shanti’s fitness background and evaluate the work of Dr. Mike Israetel who influenced our co-host in his training days.ReferencesIsraetel, M., Hoffman, J., et. al.; The Renaissance Diet. Renaissance Periodization. 09-Feb-2019. ASIN: B07NKTD9MS.Hall, K.; What is the Required Energy Deficit Per Unit Weight Loss?. International Journal of Obesity. 11-Sep-2007. 32:3 (573 - 576). Doi: https://doi.org/10.1038/sj.ijo.0803720Forbes, G.; Body Fat Content Influences the Body Composition Response to Nutrition and Exercise. Annals of the New York Academy of Sciences. 25-Jan-2006. 904:1 (359 - 365). Doi: https://doi.org/10.1111/j.1749-6632.2000.tb06482.xDrazin, B, et. al.; Effect of Dietary Macronutrient Composition on AMPK and SIRT1 Expression and Activity in Human Skeletal Muscle. Hormone and Metabolic Research. 06-Jun-2012. 44:9 (650 - 655). Doi: https://doi.org/10.1055/s-0032-1312656Support the show (https://www.patreon.com/breakingbadscience?fan_landing=true)

Dr. Louis Aronne, MD, FACP, Chief Medical Officer of Intellihealth and medical director of the Comprehensive Weight Control Center at Weill Cornell, discusses the latest medical obesity treatment: Intellihealth’s Evolve -- a technology platform for medically-supervised weight management. Louis J. Aronne, MD, FACP is a leading authority on obesity and its treatment. He is the Sanford I. Weill Professor of Metabolic Research at Weill-Cornell Medical College and directs the Center for Weight Management and Metabolic Clinical Research, a state-of-the-art, multidisciplinary obesity research and treatment program. He has an adjunct appointment at Columbia University College of Physicians and Surgeons. Dr. Aronne is Founder and CEO of BMIQ, a weight control program that is delivered by health care providers to their patients during office visits. Dr. Aronne graduated Phi Beta Kappa from Trinity College with a BS in biochemistry and from Johns Hopkins University School of Medicine. He completed his internship and residency at Albert Einstein College of Medicine and the Bronx Municipal Hospital Center, followed by a Henry J. Kaiser Family Foundation Fellowship at New York Hospital-Cornell Medical Center. He is a member of the Alpha Omega Alpha Medical Honor Society. Dr. Aronne is former president of the Obesity Society and a Fellow of the American College of Physicians. Vice-chairman of the board of the American Board of Obesity Medicine, he has authored more than 60 papers and book chapters on obesity and edited the National Institutes of Health Practical Guide to the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults. He served as a consultant to the VA Weight Management/Physical Activity Executive Council in the development of the MOVE program, the nation’s largest medically based weight control program. Dr. Aronne has won several awards for medical teaching, including the Davidoff Prize from Albert Einstein College of Medicine and the Elliot Hochstein Award from Cornell University.

Scary fact? The average person puts on 15 pounds over the holidays, but you can avoid it with healthier choices! Chrissy Barwick from Metabolic Research in JAX joins me this week to give you some tips!

Noncommunicable diseases—or NCDs—are the leading cause of death around the world. And of those NCDs, chronic cardiometabolic conditions—such as heart disease and diabetes—are particularly deadly. For more than two decades, Gökhan Hotamışlıgil, James Stevens Simmons Professor of Genetics and Metabolism and and director of the Sabri Ülker Center for Nutrient, Genetic and Metabolic Research, has been working to understand the root causes of these diseases—what goes wrong at the cellular and molecular level to make us sick. In this week's episode we share a wide-ranging conversation with Hotamışlıgil, focusing on the burden of cardiometabolic diseases, the importance of basic scientific research in treating and preventing these conditions, and the unique challenges of running a lab like the Sabri Ülker Center. You can subscribe to Harvard Chan: This Week in Health by visiting iTunes or Google Play and you can listen to it by following us on Soundcloud, and stream it on the Stitcher app or on Spotify.

Noncommunicable diseases—or NCDs—are the leading cause of death around the world. And of those NCDs, chronic cardiometabolic conditions—such as heart disease and diabetes—are particularly deadly. For more than two decades, Gökhan Hotamışlıgil, James Stevens Simmons Professor of Genetics and Metabolism and and director of the Sabri Ülker Center for Nutrient, Genetic and Metabolic Research, has been working to understand the root causes of these diseases—what goes wrong at the cellular and molecular level to make us sick. In this week’s episode we share a wide-ranging conversation with Hotamışlıgil, focusing on the burden of cardiometabolic diseases, the importance of basic scientific research in treating and preventing these conditions, and the unique challenges of running a lab like the Sabri Ülker Center. Full Transcript: hsph.me/ncd-pod

In this months Cafe Scientifique Dr Giles Yo from the Institute of Metabolic Research at the University of Cambridge askes the question: Are my genes to blame when my Jeans don't fit?. He explores the behind our metabolism and fat storage and asks if these play a more crucial role than our environment in determining our weight. We also answer audience questions that reveal how our weight may also be affected by what happens when we're in the womb and how twin studies are crucial in understanding the role of our genes. Plus, we give you a heads up on what to expect at next months event! Like this podcast? Please help us by supporting the Naked Scientists

In this months Cafe Scientifique Dr Giles Yo from the Institute of Metabolic Research at the University of Cambridge askes the question: Are my genes to blame when my Jeans don't fit?. He explores the behind our metabolism and fat storage and asks if these play a more crucial role than our environment in determining our weight. We also answer audience questions that reveal how our weight may also be affected by what happens when we're in the womb and how twin studies are crucial in understanding the role of our genes. Plus, we give you a heads up on what to expect at next months event! Like this podcast? Please help us by supporting the Naked Scientists

Guest: Robert Henry, MD Host: Steven Edelman, MD The physiological effects of glucagon-like peptide-1 (GLP-1) are exciting because of the potential clinical relevance in treating two of the major abnormalities that contribute to type 2 diabetes: impaired insulin secretion and excessive glucagon secretion. GLP-1 also appears to have effects on gastric emptying and appetite suppression. Join host Dr. Steven Edelman and his guest Dr. Robert Henry, professor of medicine at the University of California, San Diego, and chief of both the section of endocrinology, metabolism and diabetes and the Center for Metabolic Research at the VA Medical Center in San Diego.