Podcasts about metabolic dysfunction

Dr. Ron Ehrlich welcomes back Associate Professor Dr. Jim Parker to explore emerging paradigm shifts in healthcare, focusing primarily on women's reproductive and metabolic health. Dr. Parker applies Thomas Kuhn’s cycle of scientific revolutions to modern medicine, explaining how traditional systems are failing by treating symptoms rather than maintaining optimal physiology. The conversation spans the evolutionary roots of PCOS, the critical impact of maternal lifestyle ("the soil") on pregnancy outcomes ("the seed"), and a call to action for measuring fasting insulin over glucose to combat the global metabolic health crisis. ◉

Two FDA-approved MASH therapies are changing care. Learn how resmetirom and semaglutide work—and what's next in the pipeline.  Credit available for this activity expires: 6/18/27 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/updates-metabolic-dysfunction-associated-steatohepatitis-2026a1000jmw?ecd=bdc_podcast_libsyn_mscpedu

Prostate cancer is the most commonly diagnosed cancer among men and remains a leading cause of cancer-related death worldwide. While age, family history, and genetics are well-established risk factors, researchers have increasingly focused on the role of metabolic health in prostate cancer progression. Obesity, insulin resistance, type 2 diabetes, and chronic inflammation have all been associated with more aggressive disease, but the molecular mechanisms connecting these conditions to prostate cancer remain incompletely understood. A research paper titled “Epigenetic dysregulation and biological function of PDX1 in prostate cancer” was published in Volume 17 of Oncotarget. In this study, the researchers investigated whether a gene best known for regulating pancreatic function may also play an important role in prostate tumor biology. The study was led by first author Tayo A. Adeyika and corresponding author Bernard Kwabi-Addo from Howard University, Washington, DC. Full blog - https://www.oncotarget.org/2026/06/16/pdx1-may-link-metabolic-dysfunction-to-prostate-cancer-progression/ DOI - https://doi.org/10.18632/oncotarget.28854 Correspondence to - Bernard Kwabi-Addo - bkwabi-addo@howard.edu Abstract video - https://www.youtube.com/watch?v=itYVsyXJJoE Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28854 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, PDX1, DNA methylation prostate cancer, shRNA knockdown, over-expression, glucose To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Send us Fan MailThis is a clinically grounded yet elegantly strategic episode exploring the deeper physiological roots of fatigue, including nutritional deficiencies, gut microbiome imbalance, and blood sugar instability.This episode unpacks how subtle disruptions in digestion, nutrient assimilation, and glucose regulation can quietly drain energy, cloud mental clarity, and disrupt metabolic harmony. With a refined, evidence-informed approach, it highlights foundational strategies to support gut health, stabilize blood sugar, and restore optimal nutrient status for sustained vitality.Designed for listeners seeking a luxurious, intelligent approach to energy restoration, metabolic balance, and whole-body wellness.Support the showDive Deeper On Your Journey:☆ Seeking 1:1 Nutrition Support? Apply to work with Selin here☆ Book your acupuncture session at student clinic (valid until July 2027!)☆ Let's connect on Instagram☆ Read The Painless Period Guide☆ Discover the Goddess Affirmation Colouring Book 

Perimenopause, Insulin Resistance, and Persistent Muscle & Joint Pain: A Functional Medicine Framework: Nutritionist Leyla Muedin discusses perimenopausal musculoskeletal symptoms—new or persistent joint pain, muscle aches, and tendon problems—and highlights a Clinician's Journal article by physical therapist Tara Moore proposing insulin resistance screening in perimenopausal musculoskeletal care. She explains that declining estradiol during the menopausal transition can worsen insulin signaling, increase visceral fat, and reduce insulin sensitivity, affecting skeletal muscle recovery and potentially contributing to tendinopathies and poor or short-lived responses to localized treatments like PT. The framework emphasizes assessing systemic metabolic contributors (e.g., sedentary behavior, high-carbohydrate nutrition patterns, PCOS, central weight gain, stress, sleep disruption) and addressing mediators such as inflammation and impaired glucose utilization. She suggests integrating metabolic risk assessment, sleep and stress strategies, resistance training, and interdisciplinary referrals, arguing that nutrition and supplementation—especially a low-carb approach—may improve recovery and pain outcomes.

Conventional oncology often misses root causes like stress, toxins, and microbiome imbalance. Quillin outlines what a true integrative approach should look like. #RootCauseMedicine #IntegrativeOncology #CancerPrevention

High cholesterol is one of the most common reasons people are told they're at risk for heart disease. But what if cholesterol isn't the root problem? What if it's actually a signal of deeper metabolic dysfunction—and focusing on the number alone causes us to miss what's really driving cardiovascular risk? In today's episode, we explore a functional medicine approach to cholesterol and heart health, including: Why high cholesterol is often a downstream effect of insulin resistance, inflammation, and metabolic dysfunction The surprising role sugar, refined carbohydrates, and ultra-processed foods play in driving unhealthy cholesterol patterns How healthy fats, protein, fiber, and gut health influence cholesterol regulation and cardiovascular risk The nutrition and lifestyle changes that can improve metabolic health—and begin shifting key biomarkers in as little as 10 days When it comes to cholesterol, the better question isn't always, "How do I lower this number?" It's, "Why is it elevated in the first place?" By addressing the root causes—from blood sugar imbalance and inflammation to diet, movement, sleep, and stress—you can improve not just your cholesterol, but the underlying metabolic health that drives long-term cardiovascular risk. Resources Mentioned: Learn more about the 10-Day Detox: https://bit.ly/3PIUoxf Listen to my full conversation with Dr. Aseem Malhotra: https://bit.ly/4x5wEUR Track your metabolic and cardiovascular health biomarkers: functionhealth.com/mark for 160+ lab tests at just $365/year. Use code MARK2026 for $50 off. Have a question you'd love answered on Office Hours? Submit it here (0:25) Introduction (1:11) Understanding and Addressing Cholesterol with Functional Medicine (2:20) Metabolic Dysfunction, Health Reset, and Dietary Recommendations (8:07) Example Daily Meal Plan and Importance of Movement (12:46) Sleep, Stress, and Supplements for Cholesterol (14:27) Cardiovascular Risk Insights and Dr. Asim Malhotra Clip (20:30) Closing Remarks, Listener Engagement, and Social Media (21:57) Disclaimer, Medical Guidance, and Gratitude to Sponsors

Dr Nicole Needham joins Dr Oliver Gale-Grant to discuss the BJPsych Advances article "Metabolic dysfunction in severe mental illness: updates on prevalence, aetiology and treatment options". Read the article: https://doi.org/10.1192/bja.2024.52 Authors: Nicole Needham, Ivana Kamenská, Ben Meadowcroft, Rachel Brown and Helen Grossi Follow us on X @TheBJPsych #BJPAdvances Podcast transcripts available: https://www.rcpsych.ac.uk/about-us/publications-and-books/journals/bjpsych-podcasts/podcast-transcripts Disclaimer: BJPsych Advances is not responsible for statements made by podcast contributors. Unless so stated, the content of this podcast does not necessarily reflect the views of the Editor-in-Chief or the Royal College of Psychiatrists.

In this episode, Tara dives into one of the most important — and often overlooked — players in metabolic and gut health: Akkermansia muciniphila. She explains how this keystone bacteria influences weight regulation, inflammation, blood sugar balance, and gut integrity, and why both low and elevated levels can signal deeper issues in the body. Tara also breaks down the common misconceptions around weight loss, the role of the microbiome in supporting metabolic health, and why diet alone is often not enough to optimize gut function. You'll learn practical strategies to support Akkermansia naturally, when supplementation may or may not be helpful, and why proper testing is essential for understanding your unique gut environment. We cover: What Akkermansia is and why it's considered a "keystone" bacteria How it influences weight, metabolism, and inflammation Why both low and high levels can be a problem The truth about Akkermansia supplements (and why I don't rely on them) The exact foods and strategies that support healthy levels Why gut testing is essential if you actually want answers   Attend My Brand New Masterclass on May 7th at 8pm EST / 5pm PST! The Gut Fix Masterclass: Stop Blaming Food! The Real Reason You've Still Got Bloating and Pooping Problems & How to Fix Your Gut for Good Save Your Spot HERE

Liver disease is often overlooked in primary care, yet it is one of the fastest-growing causes of morbidity and mortality in the UK. Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease (NAFLD), now affects around one-third of the UK population, with prevalence rising and all-cause mortality worsening over time. In this second episode of a series on hepatology and hepatitis, Dr James Waldron is joined by Dr Rik Fijten (GP Partner, Hepatitis C GP Champion for Bexley and GP Clinical Fellow in Gastroenterology) to explore why MASLD matters to GPs, why it is so common and why primary care is central to identifying disease early and preventing progression. They discuss why clinicians need to raise this often “silent” disease proactively and how it should be considered alongside diabetes, hypertension and weight management. The conversation covers how to approach abnormal liver function tests, how to assess fibrosis risk using simple non-invasive tools and how MASLD fits into the wider cardio–renal–metabolic model of long-term condition care. The episode also looks ahead to emerging treatments and what the future may hold for patients.Access episode show notes containing key references and take-home points at:https://gpnotebook.com/en-GB/podcasts/infectious-disease/ep-205-metabolic-dysfunction-associated-steatotic-liver-disease-and-hepatitis.DisclaimerThis content is for medical education purposes only and does not constitute clinical advice. While specific drugs and dosages may be discussed, clinicians should always refer to local protocols and official prescribing information before administering medication.Did you know? With GPnotebook Pro, you can earn CPD credits by tracking the podcast episodes you listen to. Learn more.

Experts discuss the different roles of clinicians in managing metabolic dysfunction-associated steatohepatitis (MASH). Credit available for this activity expires: 4/28/27 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/multidisciplinary-management-metabolic-dysfunction-2026a1000d62?ecd=bdc_podcast_libsyn_mscpedu

Laura Beaton talks to hepatology research fellow Richard O'Halloran about his paper on metabolic dysfunction–associated fatty liver disease (MAFLD). Richard outlines risk factors and comorbidities to consider, and diagnostic tests for MAFLD. The conversation also covers management of MAFLD through risk stratification, addressing health risk behaviours, and surveillance. Read the full article in Australian Prescriber.

In the modern health landscape, neurodegenerative disorders such as Alzheimers, Parkinson's, ALS and Huntington's have become prevelant? But how did we get here? Can we reverse the trajectory? This week Dr. Barrett Deubert breaks down neurodegeneration and what the practical steps are to prevention.. . . Watch the episode on YouTube here! Click here to view the episode transcript! (00:00) - Intro (01:03) - Brain Health Overview (02:56) - What is Alzheimer's? (03:52) - Inflammation - Driver 1 (05:12) - Deficiency - Driver 2 (06:59) - Toxicity - Driver 3 (09:10) - Metabolic Dysfunction (10:55) - Prevention Tactics (16:09) - Closing Thoughts DISCLAIMERThis content is strictly the opinion of Dr. Barrett Deubert and is for informational and educational purposes only. It is not intended to provide medical advice or to replace medical advice or treatment from a physician. All viewers of this content are advised to consult their doctors or qualified health professionals regarding health questions and concerns. Neither Dr. Deubert nor the Real Health Co. takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All audience members, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement, or lifestyle program.

Dr. Hoffman continues his conversation with Dr. Bret Scher, medical director of the Coalition for Metabolic Health.

Dr. Bret Scher, medical director of the Coalition for Metabolic Health, discusses making metabolic health the foundation of medicine amid rising obesity and type 2 diabetes and reports that 93% of Americans have suboptimal metabolic health. Scher defines metabolic health using markers including glucose, insulin, triglycerides, HDL, blood pressure, and waist size, and cites evidence linking insulin resistance to heart disease, stroke, cancer, psychiatric illness, and other complications. They discuss simple self- and lab-assessments (waist-to-height ratio, fasting insulin with glucose/HOMA-IR, triglyceride-to-HDL ratio, CGMs). Scher critiques the Eat Lancet report for assuming one optimal diet, reliance on low-quality nutrition epidemiology, potential nutrient shortfalls, and environmental oversimplification, while supporting newer dietary guidelines that allow lower-carb approaches. Part two covers contradictory nutrition studies, distinctions between low-carb and ketogenic diets, emerging “metabolic psychiatry” and ketogenic therapy for mental illness and cognitive decline, limits and rebound risks of GLP-1 drugs, and Coalition efforts to improve school food and influence policy.

In this re-release episode of the Awake & Winning Podcast, Kaylor Betts sits down with returning guest Dr. Tyna Moore to tackle one of the most controversial health conversations happening right now: GLP-1 medications like Ozempic. Together they break down the difference between pharmaceutical propaganda, real clinical data, and the importance of critical thinking in a polarized health landscape. Dr. Tyna Moore is a naturopathic physician and regenerative medicine expert who has spent decades helping patients improve metabolic health, hormones, and longevity. In this conversation, she explains what GLP-1 peptides actually are, how they function in the body, and why the conversation around drugs like Ozempic has become so polarized online. Kaylor and Dr. Tyna explore metabolic dysfunction, the role of lifestyle foundations like strength training and nutrition, the dangers of oversimplified health narratives, and why nuance matters when evaluating new medical tools. This episode challenges listeners to think critically and examine how powerful interventions can be used responsibly within a comprehensive approach to health.     Episode Highlights: metabolic dysfunction crisis, GLP-1 peptides explained, Ozempic controversy, critical thinking in health, pharmaceutical industry influence, strength training for longevity, insulin resistance and middle age, metabolic health foundations, addiction and dopamine pathways, peptide therapy and longevity medicine, misinformation in health media, nuanced thinking in wellness       Takeaways:   Most chronic disease begins with metabolic dysfunction long before diagnosis GLP-1 peptides exist naturally in the body and influence appetite, metabolism, and brain signaling Lifestyle foundations like resistance training and nutrition remain non-negotiable Many health controversies exist because nuance is lost in polarized conversations Pharmaceutical tools can be useful when used responsibly within a broader health strategy Insulin resistance often develops silently for years before diabetes is diagnosed Educating yourself is one of the most powerful ways to take ownership of your health If this episode lit a fire under you, don't keep it to yourself. Screenshot it, throw it up on Instagram, and tag @thekaylorbetts or @bettsnation so we can share the love. And hey, if you're vibing with the show, take 30 seconds to drop us a 5-star review, it helps us reach more freedom-loving legends like you.   _____________________________   RESOURCES & LINKS MENTIONED IN THIS EPISODE:   Instagram | https://www.instagram.com/drtyna Ozempic Uncovered Course | https://www.drtyna.com/ozempicuncovered Podcast | The Dr. Tyna Show on Spotify | The Dr. Tyna Show on Apple Podcasts Website | https://www.drtyna.com Youtube | https://youtube.com/@drtyna _____________________________   SPONSORS: Truly Tallow | https://www.trulytallow.com/ Use code "SUNNYBALLS10" at checkout for 10% off your order _____________________________   IMPORTANT UPDATES:   Join the Betts Nation | https://bettsnation.ca/biz-kb/  Follow Kaylor on Instagram | https://www.instagram.com/thekaylorbetts/ Follow Betts Nation on Instagram | https://www.instagram.com/bettsnation/  Join Kaylor's Newsletter | https://awakeandwinning.lpages.co/optin/  _____________________________   CHAPTERS: 00:00 Introduction 01:00 The Current Political and Cultural Climate 05:00 Awakening, Politics and Independent Thinking 10:30 Why Nuance Matters in Health Conversations 14:30 What Ozempic and GLP-1 Peptides Actually Are 21:30 The Biggest Misconceptions About Ozempic 27:30 Metabolic Dysfunction and the Health Crisis 35:30 Muscle Loss, Weight Loss and Lifestyle Foundations 46:00 Why So Many Industries Fear GLP-1 Drugs 56:00 Brain Health, Addiction and Metabolic Healing 01:07:00 Risks, Side Effects and Responsible Use 01:11:00 How to Approach GLP-1 Treatment Safely  

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Seed oils are not just a modern cooking swap — they represent a dramatic shift in how we fuel our bodies. In this episode, Dr. Jen sits down with Steven Rofrano, founder of Ancient Crunch, to explore how vegetable oils moved from industrial products to dietary staples and why that change may be contributing to oxidative stress, mitochondrial dysfunction, and insulin resistance. They discuss the historical roots of seed oil adoption, the metabolic consequences of unstable omega-6 fats, the importance of ancestral food preparation methods like nixtamalization, and practical ways to reduce seed oil exposure without feeling restricted or extreme.Steven Rofrano is an entrepreneur and founder of Ancient Crunch, the company behind MASA chips and Vandy potato chips. After reversing his own chronic health issues through diet and lifestyle changes, Steven began educating others about ancestral eating and seed oil avoidance. His work focuses on bringing traditionally prepared, tallow-fried snacks to market while challenging modern food industry practices and promoting ingredient transparency.Website: https://www.masachips.comInstagram:  https://www.instagram.com/reallytanmanTiktok:  https://www.tiktok.com/@reallytanmanX:  https://x.com/reallytanmanPODCAST: Thank you for listening please subscribe and share! Shop supplements: https://healthybydrjen.shop/CHECK OUT a list of my Favorite products here: https://www.healthybydrjen.com/drjenfavorites FOLLOW ME:Instagram: https://www.instagram.com/integrativedrmom/Facebook: https://www.facebook.com/integrativedrmomYouTube: https://www.youtube.com/@integrativedrmom FTC: Some links included in this description might be affiliate links. If you purchase a product through one of them, I will receive a commission (at no additional cost to you). I truly appreciate your support of my channel. Thank you for watching! Video is not sponsored. DISCLAIMER: This podcast does not contain any medical or health related diagnosis or treatment advice. Content provided on this podcast is for informational purposes only. For any medical or health related advice, please consult with a physician or other healthcare professionals. Further, information about specific products or treatments within this podcast are not to diagnose, treat, cure or prevent disease.

Could your sugar cravings be quietly setting the stage for your next migraine, even if you think you “handle carbs just fine”?In this episode of Migraine Heroes Podcast, host Diane Ducarme explores one of the most misunderstood migraine triggers: blood sugar instability. Not sugar itself but the spikes, crashes, and nervous-system stress that come with it.Many people with migraines are told to “just cut sugar.” But migraine brains don't respond well to restriction or perfection. They respond to rhythm, stability, and context.This episode breaks down why blood sugar swings matter and how to work with cravings instead of fighting them.In this episode, you'll learn:

In this special series on Metabolic-Dysfunction Associated Steatotic Liver Disease (MASLD) and Metabolic Dysfunction-associated steatohepatitis (MASH) our host, Dr. Neil Skolnik will discuss diagnosis and treatment of MASH using a case-based approach with two master clinicians, one a hepatologist and the other a primary care physician. This special episode is supported by an independent educational grant from Boehringer Ingelheim. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health Alina M. Allen, M.D. Associate Professor of Medicine at Mayo Clinic in Rochester, Minnesota, where she serves as the Director of Hepatology and Director of the MASLD Clinic. Susan Kuchera, M.D. - Program Director of the Jefferson Health Abington Family Medicine Residency Program, Clinical Associate Professor of Family and Community Medicine in the Sidney Kimmel Medical College of Thomas Jefferson University Selected references: Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD) in People With Diabetes: The Need for Screening and Early Intervention. A Consensus Report of the American Diabetes Association. Diabetes Care 2025;48(7):1057–1082  

Deuterium disrupts mitochondrial function and DNA integrity. Learn how water, geography, and hydrogen cycles shape your health. #DeuteriumScience #MitochondrialHealth #ChronicDisease #HealthTalks

GLP-1s like Ozempic and Wegovy are dominating the conversation around weight loss — but what happens when the prescription ends? In this episode, Shana sits down with Lindsay Venn, PA-C, RD, and Clinical Director of Insulin IQ, to unpack how to reverse metabolic dysfunction without relying on lifelong medication. They explore why insulin resistance is the real root issue, how to safely taper off GLP-1s without losing your progress, what labs can reveal your true healing status, and why many chronic diseases — including cancer — are deeply tied to your metabolism. This episode is a must-listen if you're struggling with fatigue, weight, hormonal chaos, or feeling like your body just isn't responding anymore. What We Covered: Why GLP-1s may help but not heal your metabolism The most important labs to run before tapering off Common mistakes when weaning off Ozempic & Wegovy How insulin, mitochondria, and inflammation connect to cancer The role of fasting insulin, meal timing, and light in true healing The #1 lifestyle shift to calm your hormones and burn fat naturally Links & Resources: Learn more about Lindsay: vennintegrativemedicine.com Reverse insulin resistance, fatty liver, and cholesterol issues: https://shanahussinwellness.com/fattyliverguide/ Join my 90-Day Insulin Reset: https://shanahussinwellness.com/programs-courses/reset/ Connect with Shana: Instagram: @shana.hussin.rdn Facebook: Shana Hussin Wellness

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Nutritionist Leyla Muedin discusses the renaming of fatty liver disease to metabolic dysfunction-associated steatotic liver disease (M-A-S-L-D) to reduce stigma and improve diagnosis. Dr. Mary Ella's efforts at the University of Chicago Medicine highlight how this change aids in better patient identification and treatment. Leyla emphasizes lifestyle changes like a low-carb diet to manage and reverse the disease. The episode also covers the prevalence of fake extra virgin olive oil (EVOO) on the market, ways to identify authentic olive oil, and the importance of choosing quality over mass-produced options.

This episode covers:Why vitamin B1 (thiamine) may be one of the most overlooked yet critical nutrients for cellular energy, brain health, and metabolic function. They explore how widespread B1 deficiency, driven by stress, diet, toxins, and modern lifestyles, can contribute to fatigue, brain fog, cardiovascular symptoms, and chronic disease, and how cutting-edge testing and targeted nutrition may help identify and address the root causes.Dr. Darren Schmidt, D.C., is a chiropractor and clinical nutrition expert who has dedicated his practice exclusively to holistic nutrition since 1998 and is the founder and CEO of the Nutritional Healing Center of Ann Arbor. He combines modern nutritional science with time-tested therapeutic principles to help patients uncover the root causes of chronic illness and restore lasting health.Dr. Schmidt is also a sought-after speaker and educator, sharing his insights with thousands of healthcare professionals through seminars and online platforms. His work emphasizes whole-food nutrition, individualized care, and a comprehensive approach to wellness that addresses underlying mechanisms of disease.Links mentioned during this episode:Dr. Schmidt's website: https://thenutritionalhealingcenter.com/Free Initial Consultation with Dr. Megan: https://p.bttr.to/3a9lfYk Lyons' Share Instagram: www.instagram.com/thelyonsshareJoin Megan's newsletter: www.thelyonsshare.org/newsletter

Everyone knows someone with diabetes or heart disease or non-alcoholic fatty liver disease. It's impossible to find somebody who doesn't have at least one victim of these diseases in their family or friends circle. That's how widespread they've become. All these disorders share one thing in common – all are ‘lifestyle diseases' linked to insulin resistance and metabolic dysfunction. For the longest time, India's biggest public health challenge was controlling infectious diseases. But now we have an epidemic of lifestyle diseases, causing millions of premature deaths. A new book ‘Sick Nation', drills down to the root causes of this epidemic. What are the factors driving it? Why do people ignore the signs until it is too late? And what can you, as an individual, do to protect yourself from this growing epidemic of metabolic dysfunction? Guest: Karan Sarin, metabolic health coach, and author of ‘Sick Nation: Inside India's Lifestyle Disease Epidemic and How to Fix it'. Host: G Sampath Recorded, produced, and edited by Jude Weston Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Venkat Katapatna breaks down the newly adopted MASLD nomenclature and its implications for diagnosing and managing metabolic dysfunction–associated steatotic liver disease. He highlights updated AASLD guidelines, the expanding role of advanced imaging, and how radiologists are central to early detection, treatment selection, and longitudinal disease monitoring. Current Update on Nomenclature, Diagnosis,and Management of Metabolic Dysfunction–associated Steatotic Liver Disease:Radiologists' Perspective. Osta et al. RadioGraphics 2025; 45(12):e240221.   

In this special series on Metabolic-Dysfunction Associated Steatotic Liver Disease (MASLD) and Metabolic Dysfunction-associated steatohepatitis (MASH) our host, Dr. Neil Skolnik will discuss Epidemiology, Importance, Screening, Diagnosis and Treatment of MASH. This special episode is supported by an independent educational grant from Boehringer Ingelheim. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health Alina M. Allen, M.D. Associate Professor of Medicine at Mayo Clinic in Rochester, Minnesota, where she serves as the Director of Hepatology and Director of the MASLD Clinic. Selected references: Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD) in People With Diabetes: The Need for Screening and Early Intervention. A Consensus Report of the American Diabetes Association. Diabetes Care 2025;48(7):1057–1082

Visit ⁠⁠⁠https://longevitybuilders.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠to discover book and The Longevity Builder Health Lab.Episode SummaryFor decades, the standard medical advice for cancer patients was simple: "Rest. Take it easy. Avoid exertion." Today's guest has spent her career proving that advice is not just outdated—it is dangerous.In this episode, Shane Stubbs sits down with Dr. Kathryn Schmitz, the world's leading authority in Exercise Oncology. Dr. Schmitz is the scientist who literally wrote the book on moving through cancer. She spearheaded the "Exercise is Medicine" initiative and has led over $30 million in research funding to prove that exercise changes the biology of cancer.We dive deep into why building a resilient body is your best defense, the specific "Move, Lift, Eat, Sleep, Log" framework, and how resistance training impacts survivorship.PLUS: Stay tuned until the very end for a "Science Spotlight" Bonus Segment. Shane breaks down new research highlighted by Dr. Rhonda Patrick on "Shear Stress"—explaining the physics of how vigorous exercise can mechanically destroy circulating tumor cells and reverse heart aging by 20 years.The Paradigm Shift: Why the old advice to "rest" during cancer treatment is being replaced by a prescription for movement.The Science: Dr. Schmitz's $30M+ research journey and her role in writing the ACSM guidelines for cancer survivors.The Protocol: The "Move, Lift, Eat, Sleep, Log" framework for building a body that can withstand the "Big Four" (Cancer, Heart Disease, Metabolic Dysfunction, Neurodegeneration).Exercise as Medicine: How specific doses of activity can alleviate symptoms, improve chemotherapy tolerance, and boost survival rates.BONUS Segment: The physics of Shear Stress. We discuss Dr. Rhonda Patrick's breakdown of how high-intensity blood flow can kill Circulating Tumor Cells (CTCs) and scrub your arteries.Dr. Kathryn Schmitz is a Distinguished Professor of Public Health Sciences and a Professor of Physical Medicine and Rehabilitation. A trailblazer in the field of Exercise Oncology, she served as the President of the American College of Sports Medicine (ACSM) and founded the Moving Through Cancer initiative.With a PhD in Exercise Physiology, an MPH in Epidemiology, and over 300 peer-reviewed scientific papers, Dr. Schmitz is the foremost voice on the intersection of movement and malignancy. She is the author of the book Moving Through Cancer.Book: Moving Through Cancer by Dr. Kathryn SchmitzInitiative: Moving Through Cancer (ACSM)Research Spotlight: Dr. Rhonda Patrick on Shear Stress & Circulating Tumor CellsReady to put this science into practice? Don't just listen—execute.Join the Longevity Builder Health Lab to access the protocols, community, and tools you need to build a body that lasts.

Join in for a rapid-fire discussion of the latest in testing and treatment of metabolic dysfunction-associated steatohepatitis (MASH). Credit available for this activity expires: 11/26/2026 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/metabolic-dysfunction-associated-steatohepatitis-countdown-2025a1000wkh?ecd=bdc_podcast_libsyn_mscpedu

Malnutrition should be defined as any diet that results in metabolic derangement. Few Americans suffer from lack of access to calories. But we are unhealthy, with metabolic and chronic diseases increasing steadily. These are true statements, but how we should respond to them individually and societally is controversial. Peter Ballerstedt ("Sodfather of the Ruminati”) earned his bachelor's and master's degrees at the University of Georgia and his doctorate at the University of Kentucky. He was the forage extension specialist at Oregon State University from 1986 to 1992. He worked in the forage seed industry from 2011 until 2023. He is a member of several national and international scientific societies, participates in related global initiatives, and is a Past-President of the American Forage and Grassland Council. Peter's personal experience has led him to re-examine human diet and health. What he has learned doesn't agree with the advice given for the past several decades. Peter is an advocate for ruminant animal agriculture and the essential role of animal source foods in the human diet. He strives to build bridges between producers, consumers, and researchers across a wide variety of scientific disciplines – increasing awareness of metabolic health and ruminant animal agriculture's essential role in social, economic, and ecological sustainability. Peter has spoken at many different events in the US and internationally. Many of his presentations are available on YouTube. Peter and Nancy live in western Oregon (northwestern USA) with their three dogs, Conor, Noni, and Iris. The Art of Range Podcast is supported by the Idaho Rangeland Resources Commission; Vence, a subsidiary of Merck Animal Health; and the Western Extension Risk Management Education Center. Go to the episode page at https://artofrange.com/episodes/aor-169-peter-ballerstedt-metabolic-dysfunction-opportunities-eaters-and-graziers for a transcript of this interview and links to resources mentioned in the episode.

In this special series on Metabolic-Dysfunction Associated Steatotic Liver Disease (MASLD) and Metabolic Dysfunction-associated steatohepatitis (MASH) our host, Dr. Neil Skolnik will discuss Epidemiology, Importance, Screening and treatment of MASH. This special episode is supported by an independent educational grant from Boehringer Ingelheim. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health Jay Shubrook, D.O., Professor and Diabetologist in the Department of Clinical Sciences and Community Health At Touro University California College of Osteopathic Medicine Selected references: Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD) in People With Diabetes: The Need for Screening and Early Intervention. A Consensus Report of the American Diabetes Association. Diabetes Care 2025;48(7):1057–1082  

Summary2 min: Quick Intro and Welcome from REYL Founder, John Busch as this is the Re-Launch of REYL Talk and what to expect with new weekly episodes.20 min: In this episode of Real Talk, John Busch IV addresses the pressing issues surrounding men's health, focusing on the crisis of low testosterone, heart disease, and metabolic health. He emphasizes the importance of understanding these issues and taking proactive steps towards better health through lifestyle changes and supplements. The conversation aims to empower men to take charge of their health and well-being, highlighting the preventable nature of many health issues they face today.Sponsored by REYL Supplements, check out quality solutions to these issues today.TakeawaysMen need to recommit to their health daily.Low testosterone affects energy, mood, and overall health.Heart disease is the leading cause of death for men.Metabolic health is crucial for longevity and well-being.Lifestyle changes can significantly improve health outcomes.Supplements can support testosterone and heart health.Education and awareness are key to addressing health issues.Testing is easy, available and can be completed in the privacy of your home. Learn MoreMen should prioritize sleep and stress management.Community and support are vital for men's health journeys.Sound bites"Most of it is completely preventable.""The hope is it's not permanent.""We have to show up for our own health."Chapters00:00 Introduction to Men's Health Crisis08:55 Heart Health: The Silent Killer17:08 The Path Forward: Solutions and Hope

In this episode of The Better Life, Dr. Marianne Pinkston and guest Ray Solano, owner of PD Labs, a compounding pharmacy, explore the intricate link between gut health and neurological well-being. They discuss how an integrative approach, combining functional medicine principles with modern therapeutics, can address the root causes of mental health conditions like anxiety, depression, and ADHD. The conversation covers the impact of diet, genetics, and lifestyle on mental health, and introduces natural and compounded solutions like L-theanine, oxytocin, and BH4. Chapters 0:00 - 4:14: Introduction and the Problem with Conventional Solutions. Dr. Pinkston introduces Ray Solano and the topic of neurological problems. They discuss the rising rates of conditions like depression and ADD and argue that conventional medicine often only treats symptoms with pharmaceuticals, ignoring the root causes. 4:14 - 8:40: The Gut-Brain Connection and Inflammatory Foods. Ray and Dr. Pinkston explain the direct link between gut health and brain function, highlighting how neurotransmitters are made in the GI tract. They emphasize that inflammatory foods like gluten, processed items, and alcohol can significantly impact mental health. 8:40 - 13:28: The Role of Genetics and Foundational Treatments. The discussion shifts to the role of genetic predispositions (SNPs) and how lifestyle and diet can either turn these genes on or off. They introduce the importance of a holistic approach, viewing health as a puzzle with multiple pieces, including nutrition, exercise, sleep, and gut health. 13:28 - 19:38: Nutraceuticals and Hormonal Support. Dr. Pinkston and Ray detail natural, accessible remedies. Ray highlights L-theanine for its calming effects and introduces oxytocin, explaining its role in social bonding and mood elevation. They discuss its use as a compounded treatment for conditions like OCD and autism. 19:38 - 25:22: The Power of Compounded Pharmaceuticals. The focus returns to specific, targeted solutions. Ray explains BH4 (tetrahydrobiopterin), a pharmaceutical used to treat a specific genetic deficiency that impacts serotonin and dopamine production. They also discuss the compounding of natural thyroid medication and the importance of personalized medicine. 25:22 - 30:40: Progesterone and Metabolic Dysfunction. The conversation broadens to include hormonal balance, with Dr. Pinkston highlighting progesterone's role in sleep and anxiety. They also discuss metabolic dysfunction, the prevalence of belly fat, and its link to hormonal disruption and chronic disease. 30:40 - 34:25: Addressing ADD and Brain Inflammation. Dr. Pinkston and Ray focus on ADD and the importance of removing inflammatory foods from the diet. Ray introduces Synapsin, a compounded nasal spray containing RG3-Ginseng, as an effective tool for reducing brain inflammation associated with ADD and other neurological issues. 34:25 - 39:05: Conclusion and Final Thoughts. Dr. Pinkston and Ray encourage listeners to seek professional support for their health issues. They emphasize the value of telehealth and the growing field of longevity medicine, which aims to fix underlying problems rather than just treating symptoms. They conclude by providing contact information for their respective websites and podcasts. Visit my website: https://www.drpbetterlife.com/ Connect with me on social media:https://www.facebook.com/pinkston4lifehttps://instagram.com/drmariannepinkstonhttps://www.linkedin.com/in/marianne-pinkston-md-857ba069https://twitter.com/pinkston4lifehttps://www.tiktok.com/@drmariannepinkston See omnystudio.com/listener for privacy information.

We live in a culture obsessed with treating symptoms, weight gain, fatigue, high blood pressure, brain fog, poor sleep, as if each were an isolated problem. But what if these struggles aren't the problem at all? What if they're just the flashing check engine lights on the dashboard of your body, pointing to a deeper issue that's been hiding in plain sight: Metabolic Disease. In this episode, Dr. JC Doornick pulls back the curtain on why nearly every chronic health crisis in America today — from obesity and Type 2 diabetes to heart disease, hypertension, and even dementia — can be traced back to metabolic dysfunction. He explains how the healthcare industry profits from keeping us stuck in a never-ending cycle of pills, injections, and quick fixes, rather than empowering us to address the root cause upstream. You'll also learn about Metabolic Synchronization — a practical, upstream approach that helps realign the body and mind through five key foundations: Proper diet & nutrition Proper movement & muscle development Proper sleep Proper education & mental detox Proper community & support This episode is a wake-up call: the lights are flashing, and the choice is yours. Will you keep patching symptoms downstream, or will you finally pop the hood and reclaim control of your health, your mind, and your future?

Dr Ankur Vermur sees heart attack patients daily in his emergency room in New Delhi, India, almost all of them with normal cholesterol levels. We discuss the key, underappreciated metabolic risk factors for aetherosclerosis (ASCVD) and how you can avoid them with lifestyle changes.SUPPORT MY WORK

Are you ready to transform liver care with the latest evidence-based strategies? Credit available for this activity expires: 9/5/26 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/implementing-metabolic-dysfunction-associated-2025a1000n6j?ecd=bdc_podcast_libsyn_mscpedu  

BONUS ORIGINAL CONTENT: The introduction and limitations of the drug Addyi, known as the 'female Viagra,' including its side effects and mixed effectiveness; A listener's concerns about liver fibrosis, providing dietary and supplement recommendations for liver health; The impact of plastic exposure on cardiovascular health, emphasizing the widespread and harmful effects of phthalates found in plastics.

Is the promise of weight-loss drugs too good to be true? Or are they a valuable tool when used wisely? This week on Mind Over Matters, we break down the bold claims, the real risks, and the practical role that medications can play in sustainable weight loss. Inspired by Mo Perry's insightful article from Experience Life magazine, this episode offers a clear-eyed, compassionate look at one of today's most buzzed-about health topics. As a bonus, I'll share the truth about GLP-1 and Metabolic Dysfunction and help you decode what you food cravings are really trying to tell you!

Description: In the third and final episode of the healthspan series, Dr. Erin Faules and Dr. Jeff Graham explore the intersection between neurodegenerative disease and metabolic dysfunction—two often-connected drivers of decline. They discuss early detection strategies, the role of genetics, and insulin resistance, and emerging clinical tools to assess and reduce long-term risk. Key Topics Covered: Distinguishing normal aging from neurodegenerative disease Early signs of cognitive decline and how to detect them The role of APOE-4 and other genes in Alzheimer's risk Metabolic dysfunction as a driver of brain aging ("Type 3 diabetes") Blood-based biomarkers: phospho-tau, NFL, CRP, fasting insulin, and more Lifestyle interventions: sleep, strength training, CGMs, circadian-aligned eating Tools like CNS Vital Signs, PET scans, and neuroquant MRIs Supplements and prescriptions: Omega-3s, creatine, berberine, GLP-1s, inositol Connecting muscle mass to glucose control and long-term healthspan

Lara Briden is a naturopathic doctor and women's health advocate with over 25 years of clinical experience. Lara has written Period Repair Manual and Hormone Repair Manual. Her latest book, Metabolism Repair For Women,  a compassionate, science based guide to balancing insulin, losing weight and improving health, empowers women to understand and heal their metabolism for lasting health. Lara is also one of my co-founders at MenoClarity. We talk about: - The inspiration for and differences in Lara's books - The importance of understanding metabolic dysfunction - The role of hormones like insulin, estrogen, and testosterone in metabolic health and how they interact during different life stages - The impact of our modern lifestyle - Challenges in balancing blood sugar - Defining metabolic dysfunction and its manifestations - The impact of insulin resistance on women's health - Strategies to restore metabolic balance - The role of circadian rhythm - Practical tips for improving metabolic health  And lots more! If you enjoyed this episode, please subscribe, share it and leave us a 5* review on iTunes or wherever you're listening. Order the ebook or audiobook (narrated by Rachel) versions of Rachel's book, Magnificent Midlife: Transform Your Middle Years, Menopause And Beyond at magnificentmidlife.com/book The paperback can be purchased on Amazon or other online retailers: UK: https://www.amazon.co.uk/Magnificent-Midlife-Transform-Middle-Menopause/dp/173981150X/ US & Canada: https://www.amazon.com/Magnificent-Midlife-Transform-Middle-Menopause/dp/173981150X/ Australia: https://www.amazon.com.au/Magnificent-Midlife-Transform-Middle-Menopause/dp/173981150X/ You can listen to all the other episodes and get the show notes at magnificentmidlife.com/podcast. Recommended by the Sunday Times. Feedspot #9 in 40 Best Midlife Podcasts and #7 in 60 Best Women Over 50 Podcasts You'll find lots of strategies, support, and resources to help make your midlife magnificent at magnificentmidlife.com. Check out Rachel's online Revitalize Experience, a 6-week intensive small group mentoring experience or 1-1 Midlife Mentoring.

Welcome to my podcast. I am Doctor Warrick Bishop, and I want to help you to live as well as possible for as long as possible. I'm a practising cardiologist, best-selling author, keynote speaker, and the creator of The Healthy Heart Network. I have over 20 years as a specialist cardiologist and a private practice of over 10,000 patients. In this podcast, Dr. Warrick Bishop, a cardiologist and CEO of the Healthy Heart Network, discusses the critical issue of heart disease in Australia, where someone suffers a heart attack every twenty minutes. He emphasizes the importance of understanding factors such as blood pressure, weight, and cholesterol for better health. The conversation focuses on inflammation, its role in heart attacks, and how it is often linked to metabolic dysfunction and chronic conditions like diabetes.

214: In this episode, I'm diving into all things histamine—what it is, how it functions, and why it might be the missing link in your hormone and immune health journey. After sharing insights on the connection between histamine sensitivity and hormone replacement therapy (HRT), the response was massive.  I'm unpacking why histamine issues are more than just food reactions, how they relate to estrogen, menopause, and chronic inflammation, and why there's no one-size-fits-all solution. I've dealt with histamine challenges my whole life and supported countless patients through it.  This episode is a deep, honest look at the bigger picture behind histamine imbalance. Topics Discussed:  What are the symptoms of histamine intolerance and how is it connected to hormone imbalances? How does histamine affect estrogen levels and hormone replacement therapy (HRT)? What causes high histamine levels and how can you support balance naturally? What is the difference between histamine intolerance and mast cell activation syndrome (MCAS)? How do lifestyle factors, diet, and gut health influence histamine sensitivity? Sponsored By: Nutrisense | Head over to nutrisense.io/drtyna to get 30% off your Nutrisense plan. Code TYNA at checkout Puori | Go to Puori.com/drtyna and use code DRTYNA to get 20% off Timeline | Timeline is offering 10% off your order of Mitopure Go to timeline.com/drtyna LVLUP | Head over to LVLUPHealth.com and use code DRTYNA at checkout to get 20% off your order sitewide.  LMNT | Get your free Sample Pack with any LMNT purchase at drinkLMNT.com/drtyna Liver Love | Go to https://store.drtyna.com/products/liverlove Use code LIVER20 for 20% off On This Episode Cover:  00:00:00 – Introduction  00:01:57 – Histamine and Your Immune System 00:06:01 – Mast Cells, Allergies, and Inflammation 00:09:55 – My Personal Histamine Story 00:12:38 – Why Histamine Acts Fast 00:15:01 – The Role of Histamine in the Body 00:19:55 – Histamine Intolerance vs. MCAS 00:24:19 – How Menopause Impacts Histamine 00:26:32 – Why Your Histamine Is Out of Balance 00:28:20 – DAO Deficiency Explained 00:32:37 – DAO Blockers and High-Histamine Foods 00:34:32 – Lifestyle Stressors and Chronic Illness 00:36:19 – Common Mast Cell Triggers 00:42:08 – Top High-Histamine Foods 00:43:36 – What Are Histamine Liberators? 00:44:42 – Estrogen, HRT, and Histamine 00:48:10 – Histamine and Metabolic Dysfunction 00:48:34 – Recognizing Histamine-Related Symptoms 00:51:22 – My Clinical Insights on Histamine 00:54:50 – GLP-1 Meds, Histamine, and MCAS Show Links: GLP1 Uncovered Find A Doc Further Listening: EP 41: Dangers of NSAIDS - Solo Episode EP. 199 | Hot Flashes Are a Warning Sign: The Truth About Metabolic Dysfunction | Quick + Dirty EP 106: GLP1 Done Right Part 1 | Solo Episode Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease

TakeawaysMASH is a significant obesity-related complication.Semaglutide shows promise in treating MASH.Weight loss is crucial for improving liver health.Bariatric surgery remains the most effective treatment.The Essence trial indicates a 63% resolution of NASH.New medications are being developed for obesity treatment.Early intervention is key to preventing severe liver damage.Accessibility of medications is a major concern.Comparative studies are essential for evaluating new treatments.Future treatments may include innovative delivery methods.Chapters00:00 Introduction to MASH and Semaglutide Study04:29 Understanding Metabolic Dysfunction and Its Implications08:02 Essence Trial: Semaglutide's Impact on MASH12:58 Comparative Analysis of New Treatments for MASH17:30 The Future of Obesity Treatment and Drug AccessibilityJoin Vineyard - Dr. Spencer's online clinicSee the study

Subscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsBreast cancer screening, prevention, and treatment are evolving, and in this episode, integrative oncologist and former breast surgeon Dr. Jenn Simmons reveals why it's time to rethink the mammogram. With breast cancer rates rising globally, many women are undergoing aggressive treatments for conditions that may never become life-threatening. Dr. Simmons breaks down the truth about mammography risks, the limitations of early detection, and introduces safer, more effective screening methods grounded in functional medicine and metabolic health.This powerful conversation covers the real root causes of breast cancer, including chronic inflammation, environmental toxins, and metabolic dysfunction. Dr. Simmons shares her deeply personal story,  from leading a top surgical practice to becoming a patient herself — and how that experience transformed her approach to care. She also explains why prevention must go beyond imaging.You will learn how nutrition, lifestyle changes, hormone therapy, and advanced lab testing can play a transformative role in both preventing breast cancer and improving outcomes after diagnosis. This is a must-watch episode for anyone ready to move from fear to empowerment in their breast health journey.Thank you to our sponsorGet 15% off your first order with the code DRTAZ at oneskin.co/drtazConnect further to Hol+ at https://holplus.co/- Don't forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.About Jenn Simmons:Dr. Jenn Simmons is an Integrative Oncologist, Breast Surgeon, Author, Podcast Host, and the founder of PerfeQTion Imaging. Her journey into breast cancer care began with a personal tragedy. At the age of 16, Dr. Jenn's cousin, acclaimed singer-songwriter Linda Creed, died of metastatic breast cancer just weeks after Whitney Houston's recording of her iconic song, "The Greatest Love of All," topped the charts. This loss became a defining moment, inspiring Dr. Jenn to dedicate her life to transforming how we approach breast cancer treatment and prevention.Dr. Jenn became Philadelphia's first fellowship-trained breast surgeon and spent 17 years leading the field. However, her perspective changed significantly when she became a patient herself. Through this personal experience, Dr. Jenn saw how broken the conventional medical system can be. This led her to discover and embrace functional medicine, a revelation that sparked her journey towards a more holistic approach to breast cancer care.This personal journey led her to create Real Health MD in 2019, a practice dedicated to holistic healing for breast cancer. It integrates conventional wisdom with root cause medicine and the drivers of health: nutrition, lifestyle changes, detoxification, and stress management. Dr. Jenn's innovative approach doesn't stop there. As the founder of PerfeQTion Imaging, she is establishing safe imaging centers across the nation, armed with revolutionary technology that promises to redefine breast cancer screening. This technology is not only fast and safe but also comfortable, affordable, radiation-free, and boasts 40 times the resolution of MRI. It has received FDA clearance, signaling a new era in breast health and breast cancer screening.In addition to her clinical practice, Dr. Jenn hosts the "Keeping Abreast" podcast, where she shares her expertise and encourages women to take control of their breast health. Her book, "The Smart Woman's Guide to Breast Cancer," challenges conventional wisdom and promotes a holistic approach. It emphasizes the importance of nutrition, lifestyle choices, and addressing environmental toxins, providing practical steps for women seeking to navigate breast cancer treatment and regain control of their health.Beyond her professional endeavors, Dr. Jenn is a devoted wife, mother, stepmother, grandmother, and athlete. Her life's mission is deeply personal, rooted in her cousin's memory, and driven by a desire to make a lasting impact on all those who desire breast health. As she famously says, "Breast Health is Health!"Stay ConnectedSubscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsFollow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Join the conversation on X: https://x.com/@drtazmdTikTok: https://www.tiktok.com/@drtazmdFacebook: https://www.facebook.com/drtazmd/Follow Dr. Jenn Simmons on Instagram:https://www.instagram.com/drjennsimmons/https://www.instagram.com/perfeqtionimaging/Host & Production TeamHost: Dr. Taz; Produced by Rainbow Creative (Executive Producer: Matthew Jones; Lead Producer: Lauren Feighan; Editors: Jeremiah Schultz and Patrick Edwards)00:00 Introduction 02:50 Meet Dr. Jenn Simmons11:43 Discovering Functional Medicine14:36 The Flaws in Conventional Breast Cancer Screening25:01 The Mammogram Debate35:19 Self-Breast Examination: Know Your Lumps37:00 Introducing the ARIA Test43:30 The Role of Diet and Metabolic Health48:43 Alcohol and Breast Cancer Risk57:08 Hormone Replacement Therapy: Myths and Facts01:04:00 A Message of Hope and Empowerment01:06:42 Conclusion 

For decades, gut health was reduced to yogurt commercials and vague promises from probiotics that barely worked. But what if we've been targeting the wrong bugs, using the wrong delivery, and ignoring the true source of chronic inflammation and accelerated aging? In this thought-provoking episode, Dave sits down with Hannah Kleinfeld, a leader in microbiome innovation, to expose why most probiotics fail—and how one company's scientifically validated approach could redefine your gut, brain, immune system, and even your metabolism. You'll learn how dysbiosis may be wrecking your brain without you knowing it, why your probiotic likely died in your stomach acid, and the secret to rebooting your microbiome after antibiotics, GLP-1 drugs, or years of toxic exposure. This isn't just about digestion—your gut controls your cravings, energy, sleep, mood, and aging trajectory. So what's the one upgrade that can actually reset your gut… for good? What You'll Learn in This Episode: • Why your gut—not your brain—is making most of your decisions • How 93% of probiotics on the market fail before they reach your intestines • The “AB 10” protocol that rebuilds your gut after antibiotics or SIBO • What GLP-1 weight-loss drugs are doing to your microbiome (and how to stop it) • The shocking gut–brain–heart axis connection you've never heard of • Why inflammation, brain fog, and mood swings may start with leaky gut • Which probiotic strains are clinically proven to improve cognition and mood • What to do if you want to eat gluten again—or survive American wheat • How a fermented papaya concentrate could replace your acid reflux meds • Why optimizing your gut could extend your lifespan by 40% ***Get 20% off your next purchase by going to https://omnibioticlife.com/pages/dave-asprey/ or omnibioticlife.com/dave*** SPONSORS -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • OMNi-BiOTiC's Instagram – https://www.instagram.com/fatty15/ • OMNi-BiOTiC's Website: https://omnibioticlife.com/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey's Website: https://daveasprey.com • Dave Asprey's Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 03:15 – Intro • 05:05 – Probiotics, Prebiotics, and Postbiotics Explained • 08:21 – The Importance of Delivery Mechanisms • 17:36 – Addressing SIBO and Gut Health Protocols • 31:55 – The Impact of GLP-1 Drugs on Gut Health • 39:26 – The Role of Gut Bacteria in Hunger and Fasting • 40:01 – Painkillers and Gut Health: A Personal Experience • 40:51 – The Dangers of Proton Pump Inhibitors • 42:00 – The Importance of Stomach Acid • 44:55 – Probiotics for Chronic Conditions • 48:38 – The Impact of Glyphosate on Gut Health • 57:04 – Alcohol and Gut Bacteria • 01:02:01 – New Solutions for Acid Reflux • 01:07:57 – The Future of Gut Health and Longevity • 01:11:33 – Conclusion and Special Offer See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Hot flashes aren't just annoying—they're your body's way of waving a giant red flag. They're not just about estrogen; they're about metabolic health, brain function, and long-term resilience. In this quick and dirty episode, I'm breaking down exactly why normalizing hot flashes is a mistake and what they're really telling you about your health. Topics Discussed: What hot flashes really are (hint: it's not just about hormones) The link between metabolic dysfunction and brain health Why ignoring or normalizing hot flashes is a dangerous game How to support your metabolic health for long-term vitality If you've been told to “just deal with it,” this episode is your wake-up call. Let's get into it!  On This Episode We Cover:  00:00:00 – Introduction  00:01:45 – What Is a Hot Flash? 00:04:04 – Vasomotor Symptoms Explained 00:05:25 – Hot Flashes & Metabolic Dysfunction 00:09:39 – The Obesity Connection 00:12:07 – Fixing Metabolic Health 00:13:53 – Don't Normalize Hot Flashes! Show Links:  GLP-1s Done Right University  Further Listening:  GLP1s  Uncovered FREE 4 Part Video Series  EP. 171: STOP Aging with This One Simple Trick | Nathalie Niddam EP. 196 | The Answer Is The Gym | Quick + Dirty Sponsored By: BIOptimizers Go to bioptimizers.com/tyna and use promo code TYNA10 to order Masszymes now and get 10% off any order Nutrisense Head over to nutrisense.io/drtyna to get $125 off your program.  Sundays As a Listener of The Dr Tyna Show, you can Get 40% off your first order of Sundays. Go to sundaysfordogs.com/DRTYNA and use code DRTYNA at checkout. Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Ralph DeFronzo is a distinguished diabetes researcher and clinician whose groundbreaking work on insulin resistance has reshaped the understanding and treatment of type 2 diabetes. In this episode, Ralph shares insights from his five decades of research, including his pivotal role in bringing metformin to the U.S. and developing SGLT2 inhibitors. Ralph explores the impacts of insulin resistance on specific organs, the pharmacologic interventions available, and the gold-standard euglycemic clamp method for measuring insulin resistance. This episode is a masterclass in the pathophysiology and treatment of type 2 diabetes, featuring an in-depth discussion of GLP-1 receptor agonists, metformin, and a lesser-known class of drugs that opened Peter's eyes to new possibilities in diabetes care. We discuss: Metabolic disease as a foundational driver of chronic illness [4:00]; Defining insulin resistance: effects on glucose, fat, and protein metabolism, and how it varies between healthy, obese, and diabetic individuals [8:15]; The historical significance of the development of the euglycemic clamp technique for measuring insulin resistance [11:45]; How insulin affects different tissues: liver, muscle, and fat cells [15:00]; The different ways insulin resistance manifests in various tissues: Alzheimer's disease, cardiovascular disease, and more [25:00]; The dangers of hyperinsulinemia, and the importance of keeping insulin levels within a physiological range [29:00]; The challenges of identifying the genetic basis of insulin resistance and type 2 diabetes [37:00]; The “ominous octet”—a more comprehensive model of type 2 diabetes than the traditional triumvirate [45:45]; The kidneys' unexpected role in worsening diabetes, and how SGLT2 inhibitors were developed to treat diabetes [55:45]; How insulin resistance in the brain and neurocircuitry dysfunction contribute to overeating and metabolic disease [1:04:15]; Lipotoxicity: how overeating fuels insulin resistance and mitochondrial dysfunction [1:07:30]; Pioglitazone: an underappreciated and misunderstood treatment for insulin resistance [1:10:15]; Metformin: debunking the misconception that it is an insulin sensitizer and explaining its true mechanism of action [1:19:15]; Treating diabetes with triple therapy vs. the ADA approach: a better path for diabetes management [1:24:00]; GLP-1 agonists, the Qatar study, and rethinking diabetes treatment [1:31:30]; Using a hyperglycemic clamp to look for genes that cause diabetes [1:45:15]; The superiority of measuring C-peptide instead of insulin to assess beta-cell function [1:46:45]; How GLP-1-induced weight loss affects muscle mass, the benefits and risks of myostatin inhibitors, and the need for better methods of evaluating functional outcomes of increased muscle mass [1:51:30]; The growing crisis of childhood obesity and challenges in treating it [2:02:15]; The environmental and neurological factors driving the obesity epidemic [2:07:30]; The role of genetics, insulin signaling defects, and lipotoxicity in insulin resistance and diabetes treatment challenges [2:11:00]; The oral glucose tolerance test (OGTT): detecting early insulin resistance and beta cell dysfunction [2:18:30]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

Welcome to the metabolism masterclass!Dr. Ben Bikman (Ph.D Professor BYU), a powerhouse in metabolism science, joins Dave to expose the truth about insulin resistance—the silent epidemic fueling obesity, chronic disease, and low energy. Forget the outdated calorie-counting nonsense (it doesn't work)—Dr. Bikman reveals how your hormones, not just your diet, control your metabolism and what you can do to reset it fast. From debunking diet myths to uncovering why some people can eat 400 grams of carbs and never gain fat (hint: it's not what you think), this episode unpacks the real science of fat storage, energy, and optimal health. Get ready for mind-blowing insights, metabolic hacks, and a new way to think about food, fasting, and longevity. What You'll Learn: • The #1 driver of insulin resistance—and why most doctors miss it • Why eating more fat (yes, really) could be the key to reversing metabolic dysfunction • How fasting, cold therapy, and red light impact your metabolism • The truth about carbs, seed oils, and why some people can't gain fat • How to tell if insulin resistance is wrecking your energy & health Resources: • Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • Benjamin's new book How Not To Get Sick : https://a.co/d/aADlMWv • Benjamin's YouTube Page – https://www.youtube.com/@benbikman • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey's Website: https://daveasprey.com • Dave Asprey's Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com SPONSORS: -Lumiram | Go to http://healthlighting.com/dave to save 10% on your order. -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Timestamps: 00:00 Trailer 00:52 Introduction to Dr. Benjamin Bikman 02:20 The Battle Against Conventional Dietetics 04:12 Understanding Insulin Resistance 06:29 The Two Paths to Insulin Resistance 10:19 Fasting and Metabolic Health 14:11 Insulin and Cognitive Enhancement 18:16 Identifying Insulin Resistance 30:12 The Role of Insulin in Fat Storage 42:04 Understanding Glucose and Insulin Dynamics 42:26 The Role of Exercise in Glucose Regulation 42:54 AMPK and Muscle Contraction 45:21 Calories In, Calories Out Debate 46:15 The Myth of Calorie Counting 50:13 Ketosis and Metabolic Rate 51:14 Intermittent Fasting and Muscle Preservation 55:21 Insulin Resistance and Ketogenic Diets 01:02:04 Circadian Rhythm and Insulin Sensitivity 01:08:08 Environmental Toxins and Insulin Resistance 01:13:03 The Impact of Seed Oils on Insulin Resistance 01:19:22 Final Thoughts and Resources See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.