Podcasts about Northwestern Medicine

Tiziana Life Sciences CEO Ivor Elrifi joined Steve Darling from Proactive to announce an important milestone in the company's neuroimmunology pipeline, with the first three participants receiving their initial doses of intranasal foralumab in the Phase 2a Healey ALS MyMatch BANYAN clinical trial. The study is evaluating intranasal foralumab as a potential treatment for amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disease that damages nerve cells responsible for controlling voluntary muscle movement. The BANYAN trial is sponsored by Tiziana Life Sciences and co-funded by the ALS Association through its Hoffman ALS Clinical Trial Awards Program. Elrifi said the dosing of the first participants represents an important step in advancing the clinical development of foralumab and supports Tiziana's broader strategy of investigating therapies designed to target neuroinflammatory mechanisms that may play a role in neurological diseases. The Phase 2a study is initially being conducted at the Sean M. Healey & AMG Center for ALS at Mass General Brigham in Boston. The company expects the trial to expand to additional clinical sites, including Northwestern Medicine's Les Turner ALS Center in Chicago, the University of Minnesota in Minneapolis and Nova Southeastern University in Florida. BANYAN is expected to enroll 44 people with early-stage ALS who meet specific clinical and biomarker criteria. Participants must have experienced symptom onset within the previous 24 months, have a slow vital capacity of at least 65%, and demonstrate elevated levels of neurofilament light chain (NfL) of 40 pg/mL or greater. Participants will be randomized in a 3-to-1 ratio to receive either intranasal foralumab or placebo during a 12-week controlled treatment period. This will be followed by a 12-week extension phase during which all participants will receive active treatment. The primary objective of the study is to assess the safety and tolerability of intranasal foralumab in people with ALS. Investigators will also evaluate a series of secondary and exploratory endpoints intended to provide additional information on the treatment's biological activity and its potential effects on disease-related biomarkers. As enrollment and treatment continue, Tiziana expects the BANYAN study to generate additional data on the safety profile and immunological activity of intranasal foralumab in ALS patients. The company says the research could also contribute to a broader understanding of how modulation of the immune system may influence processes associated with neurodegenerative disease. #proactiveinvestors #tizianalifescienceslts #nasdaq #tlsa #newceo #ivorelrifi #Foralumab #ALS #AmyotrophicLateralSclerosis #Biotech #ClinicalTrials #NeurodegenerativeDisease #Neuroimmunology #DrugDevelopment #LifeSciences #HealthcareInnovation #Biotechnology #MedicalResearch #SteveDarling

In this episode of Better Edge, Shan H. Siddiqi, MD, discusses how connectivity-based, image-guided neuro-navigation is refining transcranial magnetic stimulation (TMS) protocols for treatment-resistant depression, anxiety and other psychiatric disorders. He details findings from a recent JAMA Psychiatry trial that found that this approach raised response rates from 60% to 80%, with lesion-network mapping potentially expanding TMS use to bipolar disorder, PTSD, OCD and Parkinson's disease. Dr. Siddiqi also highlights Northwestern Medicine's emerging interventional psychiatry program, which integrates TMS, ketamine and ECT services with a broad portfolio of neuromodulation clinical trials and a newly accredited brain stimulation fellowship.

Dr. Sterling Elliott, clinical pharmacist at Northwestern Medicine and assistant professor of orthopedics at Feinberg School of Medicine, joins Wendy Snyder, filling in for Lisa Dent, to discuss the process of weaning off and eventually quitting opioids, and the relation between GLP-1’s and remedying addiction.

Chief Medical Officer of Northwestern Medicine's Northwest region of hospitals Dr. Irfan Hafiz joins Bob Sirott to talk about a study that focuses on cancer in younger people related to alcohol, the risk of lung cancer in people who don’t smoke, and how to know if you’re eating enough whole grains. He also discusses how […]

Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice.In this Mind Moments episode, Jennifer Fokas, MD, and Minali Nigam, MD, neurologists at Northwestern Medicine with specialized training in headache medicine, join the podcast to discuss current challenges and evolving strategies in the management of cluster headache. They highlighted the substantial burden of disease, particularly among patients with chronic cluster headache, and the diagnostic difficulties that arise from overlap with migraine features. They emphasized the importance of recognizing cranial autonomic symptoms as key distinguishing features, along with typical attack duration and circadian or seasonal patterns. The conversation also covered practical approaches to acute and preventive treatment, including high-flow oxygen via non-rebreather mask, subcutaneous sumatriptan, bridge therapies, and preventive options such as high-dose verapamil and, in selected cases, lithium. The physicians also review emerging and adjunctive options while noting limitations in evidence, indications, and access. They concluded by underscoring the need for clinician preparedness and tailored therapy to enable more assertive and appropriate management of cluster headache. Looking for more Headache and Migraine discussion? Check out the NeurologyLive® Headache and Migraine focus page.Episode Breakdown: 1:54 – Biggest unmet need in cluster headache 5:01 – Importance of multimodal acute management and access issues 7:39 – Neurology News Minute  10:03 – Emerging and experimental therapies 13:03– Preventive options and special situations 17:51 – Key clinical takeaway: preparation and access to therapies The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here: FDA Approves Zilganersen, First Treatment for Alexander Disease FDA Priority Review Puts Satralizumab on Track as First MOGAD Drug FDA Approves Apitegromab for Spinal Muscular Atrophy Thanks for listening to the NeurologyLive® Mind Moments® podcast. To support the show, be sure to rate, review, and subscribe wherever you listen to podcasts. For more neurology news and expert-driven content, visit neurologylive.com.REFERENCE1. Burish MJ, Pearson SM, Shapiro RE, Zhang W, Schor LI. Cluster headache is one of the most intensely painful human conditions: Results from the International Cluster Headache Questionnaire. Headache. 2021;61(1):117-124. doi:10.1111/head.14021

This week on The Beat, CTSNet Editor-in-Chief Joel Dunning spoke with James Cox, Professor of Cardiac Surgery at the Feinberg School of Medicine at Northwestern Medicine in Chicago, Illinois, USA, and Patrick McCarthy, Executive Director of the Bluhm Cardiovascular Institute, Heller-Sacks Professor of Cardiothoracic Surgery, Professor of Cardiac Surgery at the Feinberg School of Medicine at Northwestern Medicine in Chicago, Illinois, USA, about the surgical treatment of atrial fibrillation (AF). Chapters  00:00 Intro  01:32 CMS NCD on TAVR Heart Team  04:22 JANS 1, Tarlatamab Clinical Responses   05:23 JANS 2, No Stent Hybrid Revasc Robotic TECAB  06:45 JANS 3, STS Risk Model for SAVR After TAVR  08:43 JANS 4, Surgical Exposure Bilat Lung Transplant  10:12 JANS 5, Heart Drug Failure Challenges Theory  12:53 Video 1, Off-Pump TECAB da Vinci 5  14:00 Video 2, Aortic Uncrossing, Circumflex Aorta  14:50 Video 3, Ross Face-Off, Twin Root Replacement  15:57 Dr. Cox & McCarthy, Atrial Fib Surgery  27:00 Upcoming Events  They discussed the vital importance of surgical treatment for AF, the current underutilization of these procedures, the rationale for why AF should be treated, and abating AF. Furthermore, they explored the role of AF as a quality marker, the necessity for surgeons to develop proficiency in these techniques, and the importance of resident training on this procedure. Additionally, they reviewed the benefits of devices for AF, examined arrythmias in general, and their newly published textbook on the subject. Joel also highlights recent JANS articles on the Society of Thoracic Surgeons risk model for surgical aortic valve replacement after transcatheter aortic valve replacement, a promising heart drug failing which challenged a long-held theory of disease, clinical responses to tarlatamab among patients with pulmonary carcinoid, hybrid revascularization with robotic totally endoscopic coronary bypass and stents, and the effect of surgical exposure on outcomes in bilateral lung transplantation. In addition, Joel explores off-pump totally endoscopic coronary artery bypass using the da Vinci 5, aortic uncrossing procedure for circumflex aorta, and a twin root replacement combined with coronary artery bypass after a previous Ross procedure. Before closing, Joel highlights upcoming events in CT surgery. JANS Items Mentioned The Society of Thoracic Surgeons Risk Model for Surgical Aortic Valve Replacement After Transcatheter Aortic Valve Replacement A Promising Heart Drug Fails, Challenging a Long-Held Theory of Disease Clinical Responses to Tarlatamab Among Patients With Pulmonary Carcinoid Hybrid Revascularization With Robotic Totally Endoscopic Coronary Bypass and Stents: What Are the Outcomes When The Stent Does Not Happen? Effect of Surgical Exposure on Outcomes in Bilateral Lung Transplantation: Insight From the International Multicenter Extracorporeal Life Support in Lung Transplantation Registry CTSNet Content Mentioned Off-Pump Totally Endoscopic Coronary Artery Bypass Using the da Vinci 5: Closed-Chest Stabilizer Technique Aortic Uncrossing Procedure for Circumflex Aorta Ross “Face-Off”: Twin Root Replacement Other Items Mentioned Oral Board AI Simulator CTSNet Innovation Video Competition Career Center CTSNet Events   Disclaimer The information and views presented on CTSNet.org represent the views of the authors and contributors of the material and not of CTSNet. Please review our full disclaimer page here.

In this episode, Emily C. Jakacki, President of Northwestern Medicine Delnor Hospital, discusses leading a smooth leadership transition, maintaining top decile quality scores, and focusing on patient safety, equity, and efficiency. She also shares priorities for 2026, including managing emergency department throughput, leveraging data for informed decision making, and expanding ambulatory, diagnostic, and surgical services to meet community needs.

In this episode, Emily C. Jakacki, President of Northwestern Medicine Delnor Hospital, discusses leading a smooth leadership transition, maintaining top decile quality scores, and focusing on patient safety, equity, and efficiency. She also shares priorities for 2026, including managing emergency department throughput, leveraging data for informed decision making, and expanding ambulatory, diagnostic, and surgical services to meet community needs.

Dr. Leiszle Lapping-Carr, Psychologist at Northwestern Medicine joins Lisa Dent to talk about the differences between postpartum depression and postpartum psychosis in the wake of the Lindsay Clancy trial as well as Corie Walsh’s alleged murder of her two-year-old son, Barrett, in Frankfort, Illinois.

Dr. Sterling Elliott, clinical pharmacist at Northwestern Medicine and assistant professor of orthopedics at Feinberg School of Medicine, joins Lisa Dent to discuss how to properly take Tylenol, are certain antibiotics safe to take with others, the side effects of post-breast cancer medication, and more!

Chief Medical Officer of Northwestern Medicine's Northwest region of hospitals Dr. Irfan Hafiz joins Bob Sirott to talk about the vaccine that is linked to a lower dementia risk, the FDA’s approval of a pill for pancreatic cancer, and the study of the impact of excess belly fat in older adults. He also discusses other […]

In this episode of Better Edge, Eric Ruderman, MD, sits down with Anisha Dua, MD, and Brian Jaros, MD, co-directors of Northwestern Medicine's Vasculitis Center to walk through practical approaches to vasculitis care.They discuss:• Early recognition and diagnostic workup• Treatment decisions and evolving therapies• When to refer to a specialized center• How guideline updates and clinical trials are shaping practice

Dr. Ian Grant, behavioral neurologist at Northwestern Medicine's Cognitive Neurology & Alzheimer's Disease Center, joins Bob Sirott to talk about a blood test that can detect Alzheimer’s disease, which was recently approved by the FDA. He explains how similar tests are used at Northwestern and how doctors can use this test to personalize treatment plans.

Emergency medicine physician and associate chief medical officer for Northwestern Medicine's Central DuPage Hospital Dr. Jeffrey Bohmer joins Bob Sirott to talk about how AI is used in the healthcare field and which way is the most accurate to get your blood pressure reading. He also explains how athletes use eye-training technology that also supports […]

How much time do you spend looking at a screen when you'd rather be making eye contact with your patient? In this MedAxiom HeartTalk, R. Kannan Mutharasan, MD, MBA, FACC, FAHA, cardiologist at Northwestern Medicine, shares how AI is helping clinicians stay focused on patients and uncover insights that could lead to earlier diagnoses. As the technology advances, the real work of realizing AI's potential in everyday cardiovascular care is just beginning.

Dr. Jim Adams, Chief Medical Officer at Northwestern Medicine, joins Lisa Dent to discuss recent health headlines. He addresses topics including a new GLP-1 treatment that comes in the form of a pill, an update on the loneliness epidemic, and whether or not current medicine is designed to treat illness, specifically, over treating the patient […]

Dr. Sterling Elliott, clinical pharmacist at Northwestern Medicine and assistant professor of orthopedics at Feinberg School of Medicine, joins Lisa Dent to discuss whether grapefruit interferes with prescription medications and other pharmaceutical questions from listeners.

Emergency medicine physician and associate chief medical officer for Northwestern Medicine's Central DuPage Hospital Dr. Jeffrey Bohmer joins Wendy Snyder (in for Bob Sirott) to talk about other foods that are linked to the cyclospora outbreak and if this is something that will go away on its own. He also discusses the popularity of protein-rich […]

Dr. Sterling Elliott, clinical pharmacist at Northwestern Medicine and assistant professor of orthopedics at Feinberg School of Medicine, joins Lisa Dent to discuss taking supplements in conjunction with medication, taking more than one anxiety medication, and if GLP-1’s are reshaping insurance costs for other people. Later, Dr. Elliott answers listeners’ medical questions.

Chief Medical Officer of Northwestern Medicine's Northwest region of hospitals Dr. Irfan Hafiz joins Bob Sirott to discuss the updated cholesterol guidelines for 2026, the benefits of daily multivitamins for older adults, and the differences between melatonin and magnesium. He also talks about the pros and cons of the keto diet, how an early dinner […]

Emergency medicine physician and associate chief medical officer for Northwestern Medicine's Central DuPage Hospital Dr. Jeffrey Bohmer joins Bob Sirott to talk about what foods you should try to avoid during the cyclospora outbreak and what exactly peptides are. He also discusses the symptoms of heart attacks in women and knowing what the potential causes […]

Dr. Jim Adams, Chief Medical Officer at Northwestern Medicine, joins Lisa Dent to discuss recent health headlines. He addresses topics including why we wake up in the middle of the night to use the bathroom as we get older, how measles cases are set to surpass last year’s total, the one factor that leads to […]

Elizabeth Wehrle of Montezuma went into the hospital in February and this week she gets to go home. In March, she received a first-of-its-kind lifesaving surgery, a quadruple organ transplant. On this episode, we talk with Wehrle and Dr. Ankit Bharat of Northwestern Medicine, the lead surgeon for this groundbreaking procedure. We hear about the health issues that led to these transplants, what this surgical advancement means and what goes into the decision to perform a surgery that hasn't been done before. Then, we talk with Suzanna de Baca, Iowa author of 'You Were Never Lost: Poems From The Tallgrass Prairie.' De Baca didn't expect to write about grief, but when back at the place where she spent her childhood with a friend who died, poetry and nature helped her cope.

Dr. Chitaru Kurihara, thoracic surgeon and surgical director of the Lung Transplant Program at Northwestern Medicine, joins John Williams to share details surrounding the first known quadruple-organ transplant involving retransplanted lung that Northwestern surgeons performed.

Dr. Chitaru Kurihara, thoracic surgeon and surgical director of the Lung Transplant Program at Northwestern Medicine, joins John Williams to share details surrounding the first known quadruple-organ transplant involving retransplanted lung that Northwestern surgeons performed.

Dr. Chitaru Kurihara, thoracic surgeon and surgical director of the Lung Transplant Program at Northwestern Medicine, joins John Williams to share details surrounding the first known quadruple-organ transplant involving retransplanted lung that Northwestern surgeons performed.

Emergency medicine physician and associate chief medical officer for Northwestern Medicine's Central DuPage Hospital Dr. Jeffrey Bohmer joins Bob Sirott to explain what the diarrhea-causing-parasite cyclosporiasis is and how to properly wash fresh produce, as well as why Pepto-Bismol is recommended for diarrhea while traveling. He also talks about a Northwestern study that focuses on […]

In this episode, Akhil Narang, MD, Cardiologist and Director of the Echocardiography Lab at Northwestern Medicine Bluhm Cardiovascular Institute, and Amogh Karnik, MD, Cardiologist at Northwestern Medicine Bluhm Cardiovascular Institute, join the podcast to discuss the operational requirements for successfully implementing AI in cardiovascular care. They also explore the growing role of AI-assisted imaging technology and how it is enhancing diagnostic accuracy, improving clinical workflows, and supporting better patient outcomes.

Dr. Sterling Elliott, Clinical Pharmacist at Northwestern Medicine and Assistant Professor of Orthopedics at Feinberg School of Medicine, joins Lisa Dent to answer listener questions. From statins to fish oils, Dr. Sterling Elliott gives his recommendations.

Susan Resko, CEO and President at Josselyn, joins John Williams to talk about their mission of providing quality outpatient mental health care, the work they do with Northwestern Medicine, why someone might reach out to Josselyn, the importance of having better awareness about mental health therapy, the various types of services they offer, some of […]

Dr. Dinee Simpson, Transplant Surgeon and Chief Health Equity Executive, and Ann Hall, Vice President of Administration, Northwestern Medicine, join John Williams to talk about the launch of the Kathy Schreiber Community Health Institute, the importance of community health at Northwestern Medicine, why moving barriers to care matters, what the term ‘community health’ means and […]

Dr. Quentin R. Youmans, Heart Failure and Heart Transplant Cardiologist, Northwestern Medicine, joins John Williams to talk about heart health, why he encourages patients to start small when on the path to better heart health, why it’s important to bring heart health screenings into the community, what you should know about the early signs of […]

Isa Alvarez, Northwestern Medicine Scholar, joins John Williams to talk about the Northwestern Medicine Scholars Program, what it was like being in the inaugural class of the program, how the Scholars Program helped with her preparation for college, when she first became interested in medicine, the mentors that provided support throughout her journey, the interaction […]

Isa Alvarez, Northwestern Medicine Scholar, joins John Williams to talk about the Northwestern Medicine Scholars Program, what it was like being in the inaugural class of the program, how the Scholars Program helped with her preparation for college, when she first became interested in medicine, the mentors that provided support throughout her journey, the interaction […]

Susan Resko, CEO and President at Josselyn, joins John Williams to talk about their mission of providing quality outpatient mental health care, the work they do with Northwestern Medicine, why someone might reach out to Josselyn, the importance of having better awareness about mental health therapy, the various types of services they offer, some of […]

Dr. Quentin R. Youmans, Heart Failure and Heart Transplant Cardiologist, Northwestern Medicine, joins John Williams to talk about heart health, why he encourages patients to start small when on the path to better heart health, why it’s important to bring heart health screenings into the community, what you should know about the early signs of […]

Dr. Dinee Simpson, Transplant Surgeon and Chief Health Equity Executive, and Ann Hall, Vice President of Administration, Northwestern Medicine, join John Williams to talk about the launch of the Kathy Schreiber Community Health Institute, the importance of community health at Northwestern Medicine, why moving barriers to care matters, what the term ‘community health’ means and […]

Isa Alvarez, Northwestern Medicine Scholar, joins John Williams to talk about the Northwestern Medicine Scholars Program, what it was like being in the inaugural class of the program, how the Scholars Program helped with her preparation for college, when she first became interested in medicine, the mentors that provided support throughout her journey, the interaction […]

Susan Resko, CEO and President at Josselyn, joins John Williams to talk about their mission of providing quality outpatient mental health care, the work they do with Northwestern Medicine, why someone might reach out to Josselyn, the importance of having better awareness about mental health therapy, the various types of services they offer, some of […]

Dr. Quentin R. Youmans, Heart Failure and Heart Transplant Cardiologist, Northwestern Medicine, joins John Williams to talk about heart health, why he encourages patients to start small when on the path to better heart health, why it’s important to bring heart health screenings into the community, what you should know about the early signs of […]

Dr. Dinee Simpson, Transplant Surgeon and Chief Health Equity Executive, and Ann Hall, Vice President of Administration, Northwestern Medicine, join John Williams to talk about the launch of the Kathy Schreiber Community Health Institute, the importance of community health at Northwestern Medicine, why moving barriers to care matters, what the term ‘community health’ means and […]

Dr. John Friedewald, Nephrologist at Northwestern Medicine, joins Wendy Snyder, filling in for Lisa Dent, to educate the audience on kidney transplants. He addresses the issue of finding compatible donors, the finances behind giving or receiving a kidney, as well as why someone who even want to donate their organ in the first place. Later, […]

Chief Medical Officer of Northwestern Medicine's Northwest region of hospitals Dr. Irfan Hafiz joins Bob Sirott to talk about what could be a sign of high blood pressure, why you shouldn’t scratch bug bites, and the benefits of drinking tap water when taking pills. He also discusses why you should think twice before taking a […]

In this episode, R. Kannan Mutharasan, MD, MBA, Medical Director of Health Network Development, Sarah Plaskett, PA, Vice President of Operations, and Kaleigh Powers, MSN, RN, Director of Operations at Northwestern Medicine Bluhm Cardiovascular Institute, join the podcast to discuss the importance of system integration in delivering coordinated cardiovascular care. They also share how AI is supporting clinical and operational teams by improving efficiency, enhancing workflows, and helping create a more connected patient experience.

Dr. Michael Ziffra, psychiatrist at Northwestern Medicine, joins Lisa Dent to discuss how extreme heat affects those who are neurodivergent and how hot weather affects stress and anxiety as a whole. While intense heat inherently causes people to be come more irritable and run down, certain medications only make the experience worse. Some possess side […]

In this episode, Sanjiv Shah, MD, Director of Research at Northwestern Medicine Bluhm Cardiovascular Institute, joins the podcast to discuss strategies for improving provider satisfaction and supporting clinicians in an increasingly complex healthcare environment. He also shares why strong data infrastructure serves as the foundation for innovation, enabling organizations to advance research, improve care delivery, and drive better outcomes for patients.

What if the next breakthrough in your supply chain doesn't require a massive budget or a complicated system implementation? In this episode of Power Supply, Alisha Beringer, Director of Supply Chain at Northwestern Medicine, shares how some of the most impactful innovations come from listening to frontline staff, solving real-world problems, and making better use of the tools already at your fingertips. From simple workflow improvements and AI-powered productivity tools to building trust with IT and fostering a culture of continuous improvement, Alisha offers practical strategies that healthcare supply chain leaders can apply immediately. She also explains why successful innovation starts with understanding the work, engaging the people doing it every day, and focusing on progress over perfection. If you're looking for practical ways to innovate without adding complexity, this episode is the perfect way to close out Season 18! Once you complete the interview, jump on over to the link below to take a short quiz and download your CEC certificate for 0.5 CECs! – https://www.flexiquiz.com/SC/N/ps18-08 #PowerSupply #Podcast #AHRMM #HealthcareSupplyChain #SupplyChain #Innovation #FrontlineLessons #ContinuousImprovement #Technology #Leadership

When linen spend rises, are you seeing the full picture, or just the invoice? On this week's Power Supply Vendor Spotlight™, we're joined by Jason Isherwood, CEO and Co-Founder of ClearVu-IQ, and Mike Hopkins, Vice President of Supply Chain at Northwestern Medicine, to explore how utilization intelligence is helping health systems better understand linen usage across their facilities. Learn how ClearVu-IQ reveals linen utilization patterns across health systems, helping teams move beyond assumptions and make more informed decisions about ordering, inventory, and spend. Plus, you'll hear how Mike's team at Northwestern Medicine is putting those insights into practice. What could a clearer picture of linen utilization mean for your health system? Tune in to find out! Learn more about ClearVu-IQ's utilization intelligence platform by visiting www.clearvuiq.com. To request a complimentary utilization assessment or schedule a discovery conversation, contact Jason at Jason.isherwood@linsightshealth.com. Be sure to follow ClearVu-IQ on LinkedIn for additional resources and industry insights!

Dr. Jennifer Miles-Thomas is Vice Chair of Integration and Innovation at Northwestern Medicine, Executive Treasurer of the American Urological Association, and a former CEO of one of the largest private urology groups in the country. She earned her MD at Northwestern, completed her residency and fellowship at Johns Hopkins, and her MBA at MIT Sloan. In this episode of DGTL Voices, Jennifer talks with Ed about the spinal meningitis diagnosis at age three that pointed her toward medicine, what changed when she got to MIT and started thinking alongside multinational CFOs and SpaceX engineers, and why she left a CEO seat for protected innovation time at a health system. She shares her perspective as a Black female urologist on what it took to navigate her training, how she leads through really listening, and why she believes failure is part of the path to anything worth building. https://marxadvisory.com

Chalene Johnson recorded this one on the road, starting in New York and wrapping up in Paros, Greece, and it might be one of the most information-packed episodes she's done all year. There's a comparison being made right now that Chalene can't stop thinking about. Two women, both 32, both at the height of their careers. One of them died. The parallels today are ones she felt compelled to address out loud, even without easy answers. Then a study just dropped from Northwestern Medicine that reframes the entire perimenopause and brain fog conversation, and it has nothing to do with hot flashes. If you've ever walked into a room and forgotten why you're there, this research explains something your doctor probably never mentioned. Plus, brand new data from Fitbits and Apple Health devices reveals what's actually happening to people on GLP-1 medications that nobody is talking about yet. And a Stanford study just identified a compound that could change the muscle loss conversation entirely. Chalene also gives you a heads up on a deeply disturbing documentary trending on Netflix right now and why she wants you to watch it before Friday.