Podcasts about dhea

Episode 2777 - Vinnie Tortorich speaks to nurse practitioner Cynthia Thurlow about her upcoming book and the importance of optimizing your gut. https://vinnietortorich.com/2026/03/optimizing-your-gut-cynthia-thurlow-episode-2777 PLEASE SUPPORT OUR SPONSORS Pure Vitamin Club Pure Coffee Club NSNG® Foods VILLA CAPPELLI EAT HAPPY KITCHEN YOU CAN WATCH THIS EPISODE ON YOUTUBE - @FitnessConfidential Podcast Vinnie's workout videos are available to purchase! Choose from a 2-day, 4-day, or 6-day workout–or buy all three at a discount! TO PURCHASE VINNIE'S WORKOUT VIDEOS, CLICK THIS LINK: https://vinnietortorich.com/workout Optimizing Your Gut Cynthia Thurlow is a nurse practitioner and has her own podcast, "Everyday Wellness," which focuses on women's health. (2:00) She has a book coming out, "The Menopause Gut," scheduled for release in late April 2026. You can go directly to her website and pre-order it. https://www.cynthiathurlow.com GLP1s can be helpful for morbidly obese people, but people who are not obese shouldn't be on them. Recent photos of certain celebrities show muscle wasting, which can lead to being fragile and long-term damage. Vinnie has concerns about GLP1s over the long term. What are some definitions of perimenopause, menopause, and post menopause? (27:30) The gut is important for hormonal health because it helps break down hormones for use in the body. Vinnie shares a story about his Mom and why the idea of hormones doesn't always sit well with him. (32:00) There is a difference between birth control pills and the bioidentical hormones of today. Hormones play a significant role in multiple organ systems, including the heart, bones, and brain. Is testosterone replacement necessary for men or women? (44:00) You still have to lead a healthy lifestyle; hormone replacement isn't a band-aid for a bad lifestyle. Mitochondrial health also plays a big role. (49:00) Sleep is foundational to your metabolic health as well. (54:00) Vinnie asks about DHEA and whether supplementation is beneficial. (57:00) What are things we can optimize for our health as we enter perimenopause and andropause? (1:04:00) Fiber from food is helpful for the gut for various reasons. Cynthia shares cautionary tales about being a long-term carnivore. (1:10:00) They discuss certain food addictions, especially to sugar and sweeteners. (1:13:00) A New Sponsor Jaspr Air Scrubbers has a discount code, VINNIE, that gets you $300 off for a limited time. Jaspr offers a lifetime warranty. Go to Jaspr.co for more information or to purchase. (1:05:00) You can book a consultation with Vinnie to get guidance on your goals. https://vinnietortorich.com/phone-consultation-2/ More News Serena has added some of her clothing suggestions and beauty product suggestions to Vinnie's Amazon Recommended Products link. Self Care, Beauty, and Grooming Products that Actually Work! https://www.amazon.com/shop/vinnietortorich/list/3GPVU29UHHPMY?ref_=aipsflist Don't forget to check out Serena Scott Thomas on Days of Our Lives on the Peacock channel. "Dirty Keto" is available on Amazon! You can purchase or rent it here.https://amzn.to/4d9agj1 Please make sure to watch, rate, and review it! Eat Happy Italian, Anna's next cookbook, is available! You can go to https://eathappyitalian.com You can order it from Vinnie's Book Club. https://amzn.to/3ucIXm Anna's recipes are in her cookbooks, on her website, and on Substack —they will spice up your day! https://annavocino.substack.com/ PURCHASE DIRTY KETO (2024) The documentary launched in August 2024! Order it TODAY! This is Vinnie's fourth documentary in just over five years. Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries Then, please share my fact-based, health-focused documentary series with your friends and family. Additionally, the more views it receives, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! PURCHASE BEYOND IMPOSSIBLE (2022) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries

Welcome back to Ask the Egg Whisperer! I'm so excited to have Dr. Steven Palter join me on today's episode. Dr. Palter is the medical and scientific director at Gold Coast IVF in Woodbury, New York, and an internationally recognized leader in fertility treatment. He's also the creator of the PCOS to Pregnancy Protocol -  the first comprehensive remote system targeting the root causes of PCOS and the Palter Fertility Method, a personalized approach to diagnosis and care that integrates metabolic health, surgical precision, and emerging reproductive technologies. Watch the full conversation (with more live chatted questions) on Dr. Aimee's Instagram Live.  In this episode, we tackle real questions from our community (women ranging from 36 to 47), dealing with everything from diminished ovarian reserve and repeated IVF failure to PCOS, endometriosis, and experimental treatments like mitochondrial replacement therapy. Dr. Palter and I don't always agree, and that's what makes this conversation so valuable. We get into the nuances of DHEA and testosterone supplementation, when genetic testing is worth it even with limited embryos, why your stimulation protocol might be the problem, and how targeting insulin resistance can transform outcomes for PCOS patients. In this episode, we cover: Why AMH predicts egg quantity, not quality  and why that distinction matters The truth about DHEA and testosterone priming, including a major new study showing no benefit Mitochondrial replacement therapy (three-parent IVF): promise, limitations, and what the data actually shows Fresh vs. frozen transfers with diminished ovarian reserve, and why PGTA testing is still valuable The #1 reason for immature eggs and no blasts and the protocol fix that works 80% of the time Endometriosis, BCL6 testing, and when suppression vs. surgery makes sense How targeting insulin resistance and inflammation in PCOS patients is changing outcomes dramatically Resources: Dr. Steven Palter's practice: Gold Coast IVF — goldcoastivf.com PCOS to Pregnancy Protocol by Dr. Palter Previous podcast episode with Dr. Palter on the Palter Fertility Method Dr. Aimee's fertility supplement stack Would you like to learn more about IVF?Click here to join Dr. Aimee for The IVF Class. The next live class call is on Monday, April 20, 2026 at 4pm PST, where Dr. Aimee will explain IVF and there will be time to ask her your questions live on Zoom.   Subscribe to my YouTube channel for more fertility tips! Join Egg Whisperer School Subscribe to the newsletter to get updates Dr. Aimee Eyvazzadeh is one of America's most well known fertility doctors. Her success rate at baby-making is what gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org.   Keywords fertility, IVF, egg quality, AMH, diminished ovarian reserve, DHEA, testosterone priming, PCOS, insulin resistance, mitochondrial replacement therapy, three-parent IVF, PGTA, PGT-A, genetic testing, embryo testing, endometriosis, BCL6, frozen embryo transfer, fresh transfer, egg maturity, dual trigger, ovarian PRP, progesterone support, IVF protocol, fertility doctor, reproductive endocrinology, Ask the Egg Whisperer, Dr. Aimee, Dr. Steven Palter, Gold Coast IVF, fertility supplements, CoQ10, NAD, rapamycin, hydrosalpinx, IVF failure, recurrent implantation failure, translocation, modified natural cycle

Menopause Mastery Show |  Hormone Health 101: HRT Myths & What Symptoms Really Mean | Q&A w/ Dr. Betty Murray, featuring guest Kelly Resendez

In this live Q&A episode of The Health Revival Show, Liz and Becca break down some of the most common questions they're seeing in functional medicine today—from chronic constipation to hormone therapy side effects. They dive deep into topics like redundant colon (elongated colon) and why it's often blamed for constipation when the real causes may be microbiome imbalance, bile flow issues, hormones, or nervous system dysfunction. You'll also learn why heartburn can appear after starting hormone replacement therapy (HRT) and why the hormones themselves are rarely the root problem. Instead, digestive weaknesses like low stomach acid, poor bile flow, or microbiome imbalances may be the real driver. The episode also covers teen digestive issues, exploring how puberty, estrogen fluctuations, stress, and poor digestion habits can create stomach pain after eating. Finally, Liz and Becca answer a key question about DHEA, cortisol, and adrenal health, explaining how hormone therapy influences the stress response and why supporting adrenal function is still essential. *** CONNECT:

You built a beautiful life. And somehow disappeared in the architecture.This episode explores the identity eclipse that happens when you spend a decade (or two) becoming everything to everyone else. It's about the woman who sits in the doctor's office and realizes she has no idea what brings her joy anymore. The marriage that became a logistics partnership. The body that started screaming through symptoms. And the biological reason why what you said yes to at 25 now creates resentment at 40. If you've ever wondered "who am I beyond mom/wife/career woman?" - this one will make you cry and feel seen in equal measure.In this episode we explore:Why DHEA (your stress resilience hormone) peaks at 25-30 and declines throughout life—making what was easy at 25 unbearable at 40How chronic stress depletes DHEA by 23-40%, equivalent to aging 20 years hormonallyThe silent agreements in marriage that replace intimacy with logistics (and the question: does he want you or just your usefulness?)Why perimenopause breaks you open to rewrite the rules and reclaim yourselfThree practical steps to start the joy quest and use your cycle as a map back homeResources:Book Fair Play by Eve RodskyLearn more about the Cyclical: Reclaiming You - 9 Month ProgramBook Your Free Hormone Clarity Call to start getting answers for all your hormone questions.About KateKate Nguy is the founder of Shee Revival and a Certified Hormone Health Practitioner and Cycle-Syncing Strategist who helps busy women in their 30s and 40s balance their hormones and reclaim their energy. Specializing in the hormonal ups and downs of midlife—from PMS and perimenopause to burnout and cortisol overload—Kate guides women to feel at home in their bodies and live in sync with their natural cycles. Through cycle syncing, hormone hacks, and nervous system regulation, Kate empowers women to rebalance their hormones, reconnect to their bodies, and revive the vibrant, grounded version of themselves underneath the overwhelm.Tune in now and join the movement toward better hormone health!Follow me @hormoneswithkate on Instagram for more insights, tips, and support!

Listen to the full episode Download the full episode on Apple or on your favorite podcast platforms. In this quick hits I sit down with Dr. Gillett, to exam the complex world of women's hormones today. We'll be focusing on androgens like testosterone, DHEA, and dihydrotestosterone, and their profound impact on female health. Dr. Gillett provides insights on the role of binding globulins, hormone replacement therapy, and the interplay between insulin and androgens. We also discuss the challenges of menopausal weight gain, the benefits of GLP-1 medications for weight loss, and practical strategies anyone can use for maintaining lean body mass. In this episode we discuss: How androgens such as testosterone, DHEA, and dihydrotestosterone affect women's well-being. Why sex hormone binding globulin (SHBG) is critical for hormone dynamics and stability. Understanding the impact of thyroid binding globulin and cortisol binding globulin on hormone balance. How hormone replacement therapy (HRT) influences women's bodies, especially regarding androgens. Managing testosterone replacement therapy to avoid virilization symptoms like facial hair and voice changes. The role of DHT blockers in managing androgen-related conditions. How SHBG can be harnessed for overall hormone stability and health benefits. Challenges of menopausal weight gain and how hormonal changes affect body composition. Why integrating proper lifestyle habits is essential alongside GLP-1 medications for effective weight loss. How to maintain lean body mass through hormone therapy and lifestyle changes. How oral contraceptives and other synthetic hormones impact SHBG levels and overall hormone balance. The significance of SHBG levels for individuals on hormone replacement therapy or contraceptives. Exploring different forms of testosterone administration, including subcutaneous and intramuscular injections. How estrogen and progesterone influence testosterone levels through negative feedback inhibition. How poor sleep quality and hormonal changes contribute to menopausal weight gain. The paradoxical effects of hormone replacement therapy on body composition and fat gain. Why high SHBG must be paired with adequate hormone levels to avoid feeling unwell. Discussing the challenges faced when SHBG levels are artificially high due to medication. Kyle Gillett https://gilletthealth.com/     Sponsors Get 50% off the Energy Reboot Program hackmyage.com use coupon code HORMONES50.     Are you in perimenopause or postmenopause and struggling with symptoms—but not getting the support you deserve? At Midlife Solutions, we specialize in hormone optimization for women in midlife. Our all-female clinical team offers telehealth care across all 50 U.S. states, with the ability to prescribe bioidentical estrogen, progesterone, testosterone, and thyroid medication.   Book your FREE Hormone Discovery Call Find out what's really driving your symptoms and what your next best steps are.   Visit the website: https://karenmartel.com   Shop the Midlife Solutions Store Over-the-counter bioidentical hormone creams and oils — no prescription needed. Including: • Progesterone • Estrogen Face Cream • Vaginal Moisturizer and more!   Take the Hormone Quiz Discover hidden hormone imbalances that could be driving your symptoms. Get personalized results (and yes, they may surprise you).   Women's Peptide Weight Loss Program Clinically guided, hormone-aware weight loss for midlife women.   Midlife RESET HRT Program A complete, supportive approach to hormone replacement therapy in midlife.   Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert   Karen's Facebook Karen's Instagram

Exklusiver staYoung Podcast Deal! Mit dem Code „staYoung“ erhalten Sie VITAQ®️ Omega3 1.100 für 49,00 €. inklusive MwSt. und Versand. Link: https://aspriva.com/stayoung Einmalige Verwendung pro Person. Maximal 2 Produkte. Gültig bis 31. März 2026 oder solange der Vorrat reicht. Eine Packung VITAQ®️ Omega3 1.100 enthält 90 Kapseln mit insgesamt 99.630 mg Omega-3-Fettsäuren. Pro Kapsel: 1.107 mg Omega-3, davon 667 mg EPA und 333 mg DHA. ***In dieser Folge spreche ich mit Dirk Steffens, dem wohl bekanntesten Wissenschaftsjournalisten im deutschsprachigen Raum, der als Host von „Terra X“ und dem GEO-Podcast „Kettenreaktion“ seit Jahrzehnten komplexe Naturphänomene erklärt. Dass das Thema Healthy Longevity eine enorme gesellschaftliche Relevanz besitzt, wurde für ihn spätestens dann greifbar, als er für eine große Dokumentation bei RTL Plus den Selbstversuch wagte. Wir analysieren in diesem Gespräch, warum eine erste Diagnose bei ihm zunächst für Erschütterung sorgte: Trotz eines scheinbar gesunden Lebensstils lag sein biologisches Alter drei Jahre über seinem chronologischen Alter. Wir tauchen tief in die wissenschaftliche Diagnostik ein, diskutieren die Präzision epigenetischer Uhren und hinterfragen kritisch die Mythen rund um die sogenannten Blue Zones von Okinawa bis Kalifornien. Dirk Steffens schildert eindrucksvoll, mit welchen präzisen Interventionen – von intermittierendem Fasten und Kraftsport bis hin zu spezifischen Supplements und Vagusnerv-Stimulation – er seinen Alterungsprozess nicht nur stoppte, sondern messbar umkehrte.In dieser Folge sprechen wir u.a. über folgende Themen: Warum ist das biologische Alter oft höher als das chronologische Alter, selbst bei vermeintlich gesundem Lebensstil? Was unterscheidet die Präzision epigenetischer Uhren von den Messsensoren herkömmlicher Smartwatches? Wie definieren Longevity-Kliniken den Unterschied zwischen einer Standard-Hausarztpraxis und einer ganzheitlichen Daten-Zusammenführung? Weshalb ist die sogenannte „Morbiditätskompression“ das eigentliche Ziel für ein gesundes Altern? Was steckt hinter dem Mythos der Blue Zone Okinawa und welche Rolle spielt die Realität der „Insel des Schweinefleisches“? Wie beeinflussen Investitionen aus dem Silicon Valley die Geschwindigkeit der weltweiten Longevity-Forschung? Warum ist Kraftsport ab dem 25. Lebensjahr eine der wichtigsten Versicherungen gegen spätere Sturzrisiken? Was bewirken Kälteschockenzyme im Körper und wie lassen sie sich durch tägliches Eisbaden triggern? Wie können Wirkstoff-Cocktails aus Metformin, DHEA und Wachstumshormonen die Thymusdrüse reaktivieren? Wie verändert eine konsequente Schlafhygiene und die Stimulation des Vagusnervs das allgemeine Wohlbefinden? Weitere Informationen zu Dirk Steffens findest du hier: https://de.wikipedia.org/wiki/Dirk_Steffens Du interessierst dich für Gesunde Langlebigkeit (Longevity) und möchtest ein Leben lang gesund und fit bleiben, dann folge mir auch auf den sozialen Kanälen bei Instagram, TikTok, Facebook oder YouTube. https://www.instagram.com/nina.ruge.official https://www.tiktok.com/@nina.ruge.official https://www.facebook.com/NinaRugeOffiziell https://www.youtube.com/channel/UCOe2d1hLARB60z2hg039l9g Disclaimer: Ich bin keine Ärztin und meine Inhalte ersetzen keine medizinische Beratung. Bei gesundheitlichen Fragen wende dich bitte an deinen Arzt/deine Ärztin. STY-164

Everyone is talking about inflammation. Fatigue? Inflammation. Weight gain? Inflammation. Brain fog? Inflammation. But here's the truth: inflammation is often the smoke — not the match. In this episode, Dr. Kacey Wallace breaks down what chronic inflammation actually is, what it's doing at a cellular level, and why it's usually a signal that something deeper is driving immune activation. If you feel wired but tired, inflamed, reactive, foggy, or stuck — even with “normal” labs — this episode will help you understand what's really happening beneath the surface. Inside this episode: • Acute vs. chronic inflammation (and why it matters) • Why “normal” lab ranges don't always mean optimal • The Tree Model: leaves (symptoms) vs. roots (drivers) • The 5 hidden matches that keep lighting inflammation • Why biohacking fails when foundations aren't stable • 3 simple anchors you can start this week You're not broken. You're not weak. And you're not crazy for feeling like something is off. When we support your metabolism, hormones, and brain together, your weight, energy, focus, and passion begin to return. — If you're ready to go deeper, here are your next steps: ✨ Free Guide: 9 Hidden Signs Your Metabolism Is Stuck in Survival Mode www.drkaceywallace.com/hiddenmetabolicmess ✨ Adrenal Optimization Test (see your cortisol rhythm + DHEA clearly) www.drkaceywallace.com/innercalm ✨ Resiliency Reboot Program www.drkaceywallace.com/resiliencyreboot — If this episode resonated with you, please like, subscribe, and share it with someone who needs to hear that it's not “just stress.” You deserve answers.

What if the clarity you've been searching for isn't in your mindset—but in your heart? In this conversation with Kimberly Snyder, we explore heart coherence, emotional regulation, intuition, and why so many high-achieving women are stuck in the “propelled heart” phase of constant doing. Kimberly shares the five stages of the heart + how stress, ambition, trauma, and ego keep us disconnected from our true power. We talk about nervous system rewiring, hormonal balance, and how dropping from the mind into the heart can change your relationships, health, and magnetism. From manifesting her husband in six weeks to building a wellness empire while raising two kids, Kimberly reveals how living from the heart creates ease, intuition, and alignment. If you're tired of forcing, hustling, or overthinking your next move—this episode will feel like a reset. We also talk about: The five heart stages: dark heart, propelled heart, steady heart, devoted heart, and clear heart Heart coherence and its impact on cortisol, DHEA, hormones, and longevity Why “manifestation culture” often keeps women in the mind instead of the heart Healing grief + how tragedy can open your heart Ego vs. authenticity in relationships The difference between emotional reactivity + true heart connection Nervous system regulation through heart-focused breathing Intuition vs. overthinking How partnership accelerates spiritual growth Magnetism, energy fields, and how your heart affects others Redefining success beyond hustle + achievement Why ordinary moments can feel extraordinary when you're embodied Resources: Website: mysolluna.com  Book: The Hidden Power of the Five Hearts: Empower Your Thoughts, Balance Your Emotions, and Unlock Vibrant Health and Abundance Order our book, Almost 30: A Definitive Guide To A Life You Love For The Next Decade and Beyond, here: https://bit.ly/Almost30Book.  Sponsors: Ka'Chava | Go to https://www.kachava.com and use code ALMOST30 for 15% off your next order. Ritual | Don't settle for less than evidence-based support. My listeners get 25% off your first month at https://www.Ritual.com/ALMOST30.  Hero Bread | Hero Bread is offering 10% off your order. Go to https://hero.co and use code ALMOST30 at checkout. Revolve | Shop at https://www.REVOLVE.com/ALMOST30 and use code ALMOST30 for 15% off your first order. #REVOLVEpartner BetterHelp | This episode is brought to you by BetterHelp. Give online therapy a try at https://www.betterhelp.com/almost30 and get on your way to being your best self with 10% off your first month. Chime | It just takes a few minutes to sign up. Head to https://www.Chime.com/ALMOST30. Paleovalley | Head to https://www.paleovalley.com/almost30 for 15% off your order! Our Place | Visit https://www.fromourplace.com/ALMOST30 and use code ALMOST30 for 10% off sitewide.  Fatty15 | Get an additional 15% off their 90-day subscription Starter Kit by going to https://www.fatty15.com/ALMOST30 and use code ALMOST30 at checkout.  Our Place | Visit https://www.fromourplace.com/ALMOST30 and use code ALMOST30 for 10% off sitewide.  To advertise on this podcast please email: partnerships@almost30.com. Learn More: https://almost30.com/about https://almost30.com/morningmicrodose https://almost30.com/book Join our community: https://facebook.com/Almost30podcast/groups https://instagram.com/almost30podcast https://tiktok.com/@almost30podcast https://youtube.com/Almost30Podcast Podcast disclaimer can be found by visiting: almost30.com/disclaimer.  Almost 30 is edited by Garett Symes and Isabella Vaccaro. Learn more about your ad choices. Visit megaphone.fm/adchoices

Today we will be covering the hormone DHEA. What it is and what it does, and how to use it correctly.DHEA is an anti-aging supplement. It does give an advantage. It is shown to play a role in improving libido, building muscle, and reducing risks of cardiovascular disease and cancer.To help us to share the health benefits of DHEA we have Hugh Woodward, He is the President of Health2Go, Inc the makers of Twist 25 DHEA cream.Hugh is a subject matter expert on DHEA dedicating the past 20+ years of his life to studying medical research about it, and starting a company to research, and develop the safest most effective DHEA supplement (cream) that can be made and distributed.DHEA is short for dehydroepiandrosterone, it is a naturally occurring prohormone we all make and have. DHEA is the most abundant naturally occurring prohormone in the human body.-A foundation or base building block for other smaller more specific hormones like testosterone and estrogens and about 50 other hormones that are smaller, more specific carbon chain molecules in the cascade of metabolism in the human body.-Hormones drive our energy, mood, muscle tone, fat, quality of sleep, mental sharpness, immune system, sex drive, and more.As a result of aging, and a gradual lowering of natural DHEA production after age 25, many of our natural body processes begin to slow down. As a result, most people start to have less energy and gain weight, have lower sex drive, and tend to start losing their mental sharpness and drive, have trouble sleeping and may start to get sick more often.Learn more at Twist25.com or call Health2Go with questions 1(888)489-4782 

Dr. Deb Muth 0:00 Welcome back to Let’s Talk Wellness Now. I’m your host, Dr. Zab, and we are continuing our discussion this week on 0:08 peptides. And so, if you haven’t heard our first conversation about peptides, 0:13 please go back and look at that episode. We talk all about the manufacturing, the safety, the quality of peptides, and we 0:20 dove into GLP1s. And today we’re going to dive into peptides for sexual 0:26 wellness, immune function, growth hormone, and all the amazing fun things 0:32 we can do with peptides. So, as usual, grab your cup of coffee or tea, settle 0:37 in, and let’s talk wellness now. And we’re going to take a short pause from our sponsor. I know we’ve got to do 0:44 that, you guys. They’re who keep us on the air. So, I’m going to pause for just a minute and be right back after this 0:50 message from our sponsor. Ladies, it’s time to reignite your vitality. Primal 0:56 Queen supplements are clean, powerful formulas made for women like you who want balance, strength, and energy that 1:03 lasts. Get 25% off at primal queen.com. Serenity Health. That’s primalqueen.com. 1:10 Serenity Health. Because every queen deserves to feel in her prime. All 1:15 right, everybody. We are back. And are you ready? We are talking all things peptide and I am opening the show today 1:23 with sexual wellness. Yes, I’m going there, you guys. I am going there. You 1:29 know, this has really become a big issue for people um of all ages. It’s not just 1:3 4us older people. It’s younger people, too. And there’s a whole variety of reasons why we have sexual dysfunction. 1:42 And when we’re talking about sexual dysfunction, we’re not just talking about it doesn’t work, right? Or I can’t 1:48 reach orgasm. A lot of it is around desire and um the thought of it and 1:54 wanting to connect, wanting to be kinder to one another, wanting to be touching 2:00 one another. A lot of it resolves or revolves around that. And so there are some peptides that can help us and I’m 2:08 really excited to be able to talk about those today. So the first one is called PT-141. 2:14 This targets the brain not the periphery. Right? So for many women I 2:20 will always tell you sex starts between here. It is a brain thing for us. It is 2:26 not necessarily a physical thing. For guys that’s a little different. It’s very physical. For women it’s all in our 2:32 brain. So tip for you men that are listening. You have to prime your woman’s brain first if you want her to 2:38 have sex with you that night. You have to be nice to her. You have to bring her flowers. Do the dishes for her. Do 2:45 something kind. Bring her a cup of coffee or tea or a glass of wine. Take her to dinner. You have to woo her. And 2:51 I don’t care how long you’ve been married. That has to happen. And tip number two, don’t say anything stupid 2:57 that day. I’m just being honest. When you guys say things that make us upset, 3:03 that lingers with us for the rest of the day. And it’s it’s a turnoff for us. And 3:08 for a lot of women, we can’t get past that when it comes time to snuggle at night. And sex doesn’t always have to be 3:14 at night either. So, you can tell I really love talking about this conversation, but we’re going to get into the peptide part of it because this 3:21 is going to help people. So, um, PT-141 is marketed as I’m going to slaughter 3:28 this name, Vali, and it represents a fundamentally different approach to 3:34 sexual dysfunction than the PDE5s inhibitors like Slenden, Viagra, 3:40 Tedataphil, which is Seialis. And while the PDE5 inhibitors work specifically by 3:47 enhancing blood flow to the genital tissues, PT-141 works centrally in the brain by 3:54 modulating neural s neural circuits involved in the sexual desire and 4:00 arousal. Now PT-41 is a cyclic hpatipeptide. It’s seven amino acid 4:07 peptide arranged in a cyclic structure that acts as a melanoortin receptor 4:13 agonist and with particularly the infinity for MC3R and MC4R subtypes. 4:20 It’s actually a metabolite of the melanotan 2, a peptide originally 4:26 developed for tanning that was also found to enhance sexual desire in early 4:31 studies. Now the melanoortin system in the brain is involved in multiple functions including energy homeostasis 4:39 but it also is involved in sexual motivation and arousal behaviors. The FDA approved PT-141 in 2019 specifically 4:48 for the treatment of acquired generalized hypoactive sexual desire 4:54 HSDD in permenopausal women. So for the first time we have a medication that was 5:01 approved by the FDA to use for women for sexual dysfunction. We have had all of 5:07 these seialis tedataphil viagros for men but we had nothing for women. And so 5:12 this is amazing that this is available for women and approved by the FDA. It’s a big deal. This represents the first 5:19 and only FDA approved medication specifically targeting these circuits of sexual desire rather than the peripheral 5:27 arousal mechanisms. And this indication is quite specific, meaning it was developed at some point, not lifelong. 5:35 So I if you’ve had sexual dysfunction your entire life, this medication was 5:40 not approved for you. But if it’s something that you developed over time, like when you went through pmenopause or 5:46 menopause or some women have this experience happen after childirth, that’s what we’re talking about here. 5:53 Now, it’s also not just um supposed to be used if you dislike your partner, 5:59 right? If your relationship is bad and you dislike your partner, this probably isn’t going to fix a ton. It might help 6:05 a little bit, but that’s not what it’s meant for. So, you really have to know what you’re using it for and why. And 6:11 the other thing that I would say is this is something that we don’t go to if your hormones are not balanced properly. You 6:17 have to balance your hormones properly before using something like this because it still may not work. Now, the only 6:24 caveat to that is if you’re a woman that has a risk of breast cancer and can’t use hormones, then that’s a different 6:31 story and we would have that conversation about whether or not this medication would be appropriate for you. Now, the FDA label specifies PTA1 uh 6:39 PT-141 as it not being indicated for HSDD in causes where low sexual desire 6:46 is due to coexisting medical or psychiatric conditions, problems with relationships, like we had talked about, 6:53 side effects to medications or other substance use. This specifically reflects the importance of differential 6:59 diagnosis. Low sexual desire can have many root causes and PT-41 is only 7:05 appropriate when those causes have been ruled out. Now, I have I used PT41 in 7:10 people who have sexual dysfunction issues as a result of using 7:16 anti-depressants. Yes, I have. I’ve used Flynn in that effect as well. And it 7:21 does work sometimes, but it doesn’t work completely. But you need to know that that is not what the approval is for the 7:27 FDA. So that is done in something that we call off label use. So very important 7:33 to know. Now in these clinical trials leading to FDA approval, this was published by Kinsburg and colleagues in 7:40 obstetrics and gyne gynecology in 2019. PT-141 demonstrated statistically 7:46 significant improvements in sexual desire and decreases in distress related 7:51 to low desire compared to placebo. The effects manifest over 45 minutes to 7:56 several hours after the injection and the mechanisms involved modulation of dopamine and melanoorton pathways in the 8:04 hypothalamus and the brain regions that involved sexual motivation. Now cardiovascular effects of PT 141 require 8:12 careful attention. This drug causes transient increases in blood pressure about 3 to four points and transient 8:20 decreases in heart rate. And because of this, it is contraindicated in patients 8:25 with uncontrolled hypertension or known cardiovascular disease. And it has been studied in patients who’ve had recent 8:32 cardiovascular events or sorry hasn’t been studied hasn’t been studied in patients who’ve had recent 8:39 cardiovascular events. So patients need to have their blood pressures checked before starting therapy. Nausea is 8:45 extremely common. It is one of the biggest things I often will tell people to take an anti-nausea medicine if 8:52 they’re going to do this because the last thing you want to do is inject this medication and think it’s going to give 8:57 you this great time with your partner and you’re so nauseated that you can’t even perform, don’t want to kiss, don’t 9:05 want to do anything. It it can be pretty profound for some people. um it does affect about 40% of the patients in 9:12 clinical trials which is why many clinicians require or recommend an 9:17 anti-nausea medication like I had just said other common adverse effects include flushing injection site 9:24 reactions headache in about 13% of the population which I have seen worse if 9:30 people are prone to headaches and the headaches are pretty intense so I will also have them premedicate if they have 9:36 that um sensitivity ity with a Tylenol or Advil, Alie, whatever it is they 9:42 typically use for their headaches to help prevent that from occurring. Now, some patients also experience a 9:50 generalized hyperpigmentation of their skin, particularly in areas with chronic friction, and this may not be reversible 9:57 after discontinuation. So from an integrative perspective, PT-41 10:03 represents one tool in addressing female sexual dysfunction, but it should never be the first or only intervention. And 10:11 low sexual desire in women is complex. Multiffactorial involving hormonal imbalances, low testosterone, estrogen 10:18 deficiency, progesterone imbalances, thyroid dysfunction, adrenal dysfunction, and with elevated or 10:24 disregulated cortisol levels, sleep deprivation, relationship issues, unresolved trauma, including sexual 10:31 trauma, chronic pain, body image concerns, and medication side effects such as SSRIs are notorious for this. So 10:39 a comprehensive hormone panel including total and free testosterones, estradile, 10:45 progesterone, DHEA, thyroid function in cortisol assessment, ideally four-point 10:51 cortisol, salivary should precede any pharmacological intervention. And additionally, addressing the 10:57 psychological component and relationship dimensions through appropriate therapy is necessary. I have a lot of patients 11:03 that say, “This is just too much work for sex. I don’t want the side effects. I don’t want to deal with this.” and that’s totally fine. But for some 11:09 people, their sexual dysfunction is actually causing more problems on their 11:14 relationship and they want to do something to fix that. And just know that if you’re using a peptide like this 11:20 that comes with some of these side effects and you have to premedicate for it, it is not the end of the world. Um, 11:27 but it may be a possibility that you may need that. So, let’s dive into body composition and growth hormone access. 11:34 So Tesmarellin is the only FDA approved GH 11:40 analog. Tesarelin is marketed as Agrifta and Agria SV. It is a synthetic analog 11:48 of human growth hormone releasing hormone. So GH RH human growth hormone 11:53 releasing hormone. These things are such long names it’s confusing and it’s difficult to spit out, right? It 11:59 consists of 44 amino acids. The structure is identical to our own 12:05 body’s growth hormone GHR um with the addition of trans3 hexonol group which 12:14 stabilizes the molecule that extends its half-life compared to the native GHR. 12:19 The mechanism of tesmarellin is elegant in its preservation of physiological 12:24 growth hormone GH secretion patterns and rather than administering an exogenous 12:30 growth hormone directly, tesmarillin binds to the GH receptor in the anterior 12:36 pituitary gland stimulating the indogenous pulsatile release of GH. So 12:42 you know it it’s slower in that stimulation and it pulsates instead of a direct rise and fall. This pusile 12:49 pattern more closely mimics natural GH secretion which occurs in bursts 12:54 primarily during sleep. The GH then stimulates the liver to produce insulin-like growth factor IGF-1 which 13:01 exerts many of the downstream metabolic effects including lipolytic effects on 13:07 the atapost tissue. So fat atapose and how we break that down. The FDA approved 13:13 tesmarellin in 2010 for a very specific narrow indication, the reduction of 13:19 excess abdominal fat in HIV infected patients with lipodistrophe. This 13:25 condition characterized by abnormal fat redistribution with accumulation of visceral body fat and the loss of 13:32 subcutaneous fat in face and limbs developed as a complication of an 13:37 antiviral therapy particularly with older protease inhibitor reg uh 13:42 regimens. The visceral fat accumulation in patients is not just cosmetic. It’s associated with increased cardiovascular 13:49 risk, insulin resistance, and inflammatory markers. The pivotal trial that led to the FDA approval included 13:56 work by Stanley and colleagues published in the annuals of internal medicine in 2014. It demonstrated that tesmarillan 14:03 significantly reduced the visceral atapose measured by CT scan by approximately 15 to 20% which is a 14:10 significant difference to placebo over a short period of time only 26 weeks. Now, 14:16 interestingly, the total body uh weight typically remained stable or even 14:21 increased slightly as the reduction of visceral fat was sometimes offset by increases in lean body mass or 14:28 subcutaneous fat. This highlights an important point. Tesmearellin is not a weight loss drug in its conventional 14:34 sense. Its effects are specifically on body composition and fat redistribution. 14:40 Now the glucose metabolism effects of tesmarellin do require careful monitoring because GH and IGF1 can 14:47 induce insulin resistance. Tesmearellin can increase glucose levels and hemoglobin A1C and in these clinical 14:54 trials glucose tolerance and new onset diabetes occurred in some patients. So 14:59 this creates a therapeutic paradox while res reducing visceral fat we should theoretically improve metabolic health. 15:07 The GH mediated insulin resistance can worsen the glycemic control and patients 15:12 with diabetes require particularly close monitoring. The potential need for adjustment in diabetic medications can 15:19 occur. So I already know what you guys are thinking. Can I use Tesmarellin and 15:24 GLP1 at the same time? And the answer is yes. Especially in those people that we 15:30 know have an insulin resistance already or are prone to that, we can use lowd 15:36 dose micro doing GLP-1 along with tesmarellin to help prevent this from 15:42 occurring um or reduce the risk of it occurring. Now there are some other adverse related problems to growth 15:49 hormone access which include fluid retention which can uh manifest as uh 15:55 ankle swelling, joint pain, muscle pain, paristhesas, carpal tunnel syndrome is 16:01 common to see. Of course you can always see injection site reactions reported about 26 to 30% of the time in the trial 16:08 participants. And this also theoretically has a concern about IGF-1 elevation potentially promoting 16:14 malignancy through long-term data is limited. So we have to be cautious about 16:20 this but it is a growth hormone and anything that is a growth hormone can cause cells to grow and it cannot 16:26 necessarily differentiate between healthy cells and bad cells. So the drug is contraindicated is contraindicated in 16:33 patients with active cancer and in patients with the disruption of the HPA access from conditions like pituitary 16:40 tumors, pituitary surgery, head of radiation um and traumatic brain injury. 16:46 Now off label use of tesmarellin for general anti-aging or body composition 16:51 optimization in non-HIV population, it doesn’t have FDA approval. There is no 16:58 FDA studies. um that promote this, but practitioners do prescribe it for these 17:04 purposes under an experimental and not supported by FDA approved indications. 17:10 And um from an integrative medical standpoint, optimizing natural growth 17:15 hormone secretion through lifestyle interventions, high quality sleep is important. GH primarily is excreted 17:22 during sleep and deep sleep waves. So improving your deep sleep is important. Intermittent fasting can also increase 17:28 growth hormone by five-fold as demonstrated in a Hartman and colleagues uh study from the journal of clinical 17:35 endocrinology and metabolism in 1992. And highintensity interval training, adequate dietary protein, blood sugar 17:42 control, these all can help naturally increase your growth hormone. So, let’s 17:47 dive in now and talk about bone health. peptide hormones um such as oh I’m gonna 17:54 I’m gonna really slaughter this name. Terraparatide is a true bonebuilding 18:01 peptide. It’s marketed as forio. It’s a recumbent form of the first 34 amino 18:08 acids out of 85 of the human parathyroid hormone PTH. It represents a unique 18:13 approach to osteoporosis treatment because it’s one of the few truly anabolic anabolic bone therapies meaning 18:21 it actively binds new bone rather than simply preventing bone loss. The biology 18:26 of parathyroid is fascinating and seemly contraindicated or uh contradictory. 18:32 Continuously sustained elevations of PTH as occurs in hyperarathyroidism 18:37 is catabolic to bone. So people who have hyperarothyroidism typically have significant bone loss 18:44 especially before it’s diagnosed and it causes causes increased bone 18:49 reabsorption loss of bone density increased fracture risk and however 18:55 intermittent exposure to PTH as achieved with once daily uh injections of forio 19:01 has the opposite effect. This intermittent exposure preferentially stimulates osteoblasts bone building 19:08 cells over osteoclasts bone reabsorbing cells and it leads to 19:13 the net bone formation. So terraparatide binds to the PTH receptors on 19:20 osteoblasts and renal tubular cells in bone. It increases the number of 19:25 activity of osteoblasts stimulating the differentiation of osteoblast precursor cells and may 19:32 reduce osteoblast apoptosis basically programmed cell death allowing this bone 19:37 building cell to work longer. The result is increased bone formation, improved bone architecture and tbacular 19:45 connectivity and ultimately increased bone mineral density um particularly in the hip and the spine which is so 19:51 difficult to regain. The FDA approved this medication in 2002 based on pivotal 19:57 studies by Near and colleagues published in the New England Journal of Medicine in 2001 which demonstrated significant 20:05 reductions in vertebral and non-vebral fractures in post-menopausal women with 20:11 osteoporosis. specifically uh reduced new vertebral fractures by 20:17 65% and nonvettebral fragility fractures by 53% 20:23 compared to placebo over a median followup of 21 months. This is really 20:29 incredible because we have not seen this kind of um change uh in other 20:35 medications that we’ve used for osteoporosis. So current FDA approval 20:40 indicates uh this for post-menopausal women with osteoporosis at high risk for 20:46 fracture, men with primary or hypoconatal osteoporosis at high risk for fracture 20:53 and men and women with glucocord cord glucocordide 21:00 induced osteoporosis at high risk for fracture. The high risk qualifier is 21:05 important. uh terrapeptide is reserved for patients with severe osteoporosis, 21:11 multiple fractures, very low low bone density and those who have failed or are 21:16 intolerant of other therapies. The most significant concern for this medication 21:21 is highlighted in a boxed warning with rat toxicology studies where it caused 21:27 osteioaroma which is a bone cancer in a dose dependent and treatment duration dependent manner. The revolence of this 21:34 finding to humans is debated. Rats have fundamentally different bone biology than humans with continuous bone growth 21:41 throughout life and different PTH receptors. Now post marketing 21:46 surveillance in humans hasn’t shown a clear increase in osteocaroma risk but 21:51 theoretically concerns persist and because of this terapeptide is 21:57 contraindicated in patients at risk baseline risk for osteioaroma 22:02 including those with pageantss disease of the bone unexplained elevations of alkaline phosphate prior skeletal 22:10 radiations bone metastases or skeletal malignancies and pediatric patients or young adults 22:16 with open hyes. There’s also a lifetime treatment duration of only 2 years and 22:22 terrapeptide can cause transient hypercalcemia. So an elevated blood calcium and as PTH normally increases 22:31 calcium levels by enhancing bone reabsorption, increasing renal calcium 22:36 reabsorption and promoting activation of vitamin D which increases intestinal calcium absorption. Some patients 22:43 experience orthostatic hypotension within 4 hours of injecting requiring 22:48 caution in at risk populations for blood pressure. Common side effects include 22:53 muscle pain, joint pain, pain in the limbs, nausea, headache, and dizziness. So from an integrative bone health 23:00 perspective, terrapeptides should be part of a comprehensive strategy. Adequate calcium intake, 500 to a,000 23:08 milligrams of calcium a day from food and supplements combined. and vitamin D. 23:13 Getting vitamin D levels of at least 50 to 80 are essential for the drug to work 23:20 optimally. But beyond this, bone health requires vitamin K2, which directs calcium into the bones rather than soft 23:27 tissues, magnesium as a co-actor in bone metabolism, trace minerals like boron, 23:33 copper, silica, and of course, adequate protein intake, which many of us, especially as women, don’t do 0.8 8 to 1 23:42 gram of protein per kilogram of body weight, weightbearing exercise. Of 23:47 course, these all provide mechanical signals that complement the biochemical 23:52 symbol uh signals of terrapeptide. Sequential therapy is also critical. The 23:58 bone mass gains from terraparatide can be lost if patients don’t transition to 24:05 an anti-resorbbitive agent a bisphosphinate after completing this therapy and the anabolic effects to 24:12 build bone but maintaining the new bone requires preventing excess reabsorption. 24:18 So positive things about this but there are definitely some concerns as well. So 24:23 the next one we’re going to talk about is Lu Prolrooide. It is marketed under 24:29 the multiple brand names of Lupron, Depo, Eligard, and it’s a synthetic 24:34 nonapeptide analog of naturally occurring ginonadotropen releasing 24:39 hormone G&R, also called luteinizing hormone releasing hormone, LHR. 24:46 It’s a fascinating example of how manipulating natural hormonal feedback systems can create therapeutic effects. 24:53 So, G&RH is normally secreted in a pulsatile fashion by the hypothalamus 24:59 and travels to the anterior pituitary where it binds to G&R receptors and 25:05 stimulates the release of luteinizing hormone LH and follical stimulating hormone FSH. These ginatotropins signal 25:13 the ovaries or the testes to produce sex hormones, estrogen, progesterone in 25:18 women, testosterone in men. Uh, luoprololi lupron as a GNR agonist 25:26 initially mimics the action of natural G&R causing an acute flare response with 25:33 uh increased LHFSH secretion which temporarily increases sex hormone 25:38 production. However, the continuous administration which is in the depo 25:44 formulations, the GNR receptors in the pituitary become desensitized and 25:50 downregulated. And after about 2 to four weeks of continuous exposure, LH and FSH 25:56 secretion is profoundly suppressed, leading to what’s termed as chemical 26:01 castration. Testosterone levels in men drop to castrated levels less than 50 26:08 and estrogen production is marketkedly suppressed in women. This bifphasic 26:13 response creates both therapeutic applications and management challenges in prostate cancer where tumor growth is 26:20 typically androgen dependent and the ultimate goal is testosterone suppression. However, the initial 26:27 testosterone surge during the flare phase can temporarily worsen symptoms potentially causing increased bone pain, 26:34 urinary obstruction, or even spinal cord compression in patients with metastatic 26:40 disease. This is why uh luoprolide is often started with an anti-ad androgen 26:47 like bicladamide for the first two to four weeks to block the effects of the 26:52 testosterone surge. The FDA has approved lupalide for multiple indications across 26:59 formulations. In oncology, it’s used for palletive treatment of advanced prostate cancers. In gynecology, various 27:06 formulations are approved for endometriosis, for pain management and lesion reduction and for fibroids. 27:13 Typically for pre-operative uh hematological improvement in anemic patients. In pediatrics, it’s used for 27:20 central precocious p puberty basically to halt the premature sexual development of these young people. Now, there are 27:28 adex uh adverse effect profile that reflects profound hormonal suppression. 27:34 In men treated for prostate cancer, hot flashes affect about 59% of the patients. Other common effects include 27:41 general pain, swelling, bone pain. Um long-term use of these medications leads 27:47 to metabolic changes. It increases fat mass. It decreases lean mass. It worsens 27:53 insulin sensitivity, disrupts the cholesterol uh lipid panels, increases 27:59 diabetic risk, has some concerns over cardiovascular disease. And the metaanalysis have shown increased risks 28:06 of heart infarction, myocardial inffection, sudden cardiac death, and stroke in populations receiving 28:13 long-term androgen deprivation therapy. The bone effects are particularly dramatic. Without sex hormones, bone 28:20 density decreases significantly, typically 3 to 4% per year during the 28:26 first two to three years of therapy. And this bone loss may not fully be reversible after the the therapy 28:32 discontinues. The American Society of Clinical Oncology recommends bone density monitoring and consideration of 28:39 bisphosphinates uh in men receiving long-term androgen deprivation. In women treated for 28:46 endometriosis or fibroids, the estrogen suppression creates a hypoestrogenetic state similar 28:54 to menopause. Hot flashes affect 90% of patients with other common effects 29:00 including headaches, emotional irritability, decreased sex drive, vaginal dryness, bone density loss. And 29:08 because of these bone concerns and treatment duration with endometriosis, typically limited to six months, though 29:14 some formulations allow for longer use with adback hormonal therapy to 29:20 partially mitigate these side effects. The mood and cognitive effects can be s 29:25 significant. I’ve seen it over the years. the depression, the memory impairment, difficulty focusing and 29:31 concentrating. It can be very very traumatic and the quality of life that 29:37 happens for these uh women and men can be unbearing for many of them. Um, from 29:44 an integrative perspective, patients receiving this medication need comprehensive support care. Bone health 29:51 interventions using calcium, vitamin D, vitamin K2, weightbearing exercise, 29:58 cardiovascular risk management becomes critical, including blood pressure monitoring, lipid management, diabetes 30:05 screening. For hot flashes management, some patients respond to black coohos, 30:10 sage, or vitamin E. Though evidence is mixed and individual response varies, 30:16 omega-3s may help with the mood and the inflammation, resistance training becomes specifically important to 30:22 preserve lean muscle mass in the face of hormonal suppression. 30:27 Now there’s something called calcetonin salamon which is marketed as miaelin. 30:34 It is a nasal spray. It is now discontinued. And foral is the new 30:39 synthetic polyeptide hormone of 32 amino acids identical to calcetonin of salamon 30:47 origin. It represents an interesting case study in how initial promise gives 30:52 way to safety concerns that regulate a therapy to historical footnote status. 30:58 Calcetonin is naturally occurring hormone in humans. It’s secreted by the paraphalicular sea cells in the thyroid 31:04 gland. Its primary physiological role is to lower blood calcium levels by 31:10 directly inhibiting osteoclast activity, reducing bone reabsorption, increasing 31:16 renal calcium secretion or excretion, and possibly reducing the intestinal 31:21 calcium absorption. So, salamon calcetonin is used therapeutically because it’s more potent and longer 31:27 acting than human calcetonin. The FDA initially approved calceton and salmon 31:34 for several indications post-menopausal osteoporosis in women more than five 31:39 years post-menopausal when alternative treatments are not sustainable. Padet’s 31:44 disease for bone and hypercalcemium as emergency treatments. The nasal spray formulation is particularly popular for 31:53 osteoporosis because it offered a non-injectable alternative to bisphosphinates. 31:58 However, in 2012, the European Medicine’s Agency, EMA, conducted a 32:05 comprehensive safety safety review after a poolled analysis of 21 clinical trials 32:10 involving over 10,000 patients showed a statistically significant increase in 32:15 malignancy risk in patients treated with calceton salamon compared to compared to 32:21 placebo. The overall malignancy rate was 4.1% in calcetonin treated patients 32:28 versus 2.9% in placebo patients. The types of cancer 32:34 varied with no single cancer type predominating, making it difficult to establish a clear mechanistic link. 32:41 However, the signal was concerning enough that the EMA restricted the use of calcetonin containing medicines. In 32:48 the United States, the FDA issued communications about malignancy signal and conducted its own review. While they 32:56 didn’t fully withdraw the drug, the cons consensus shifted dramatically. The nasal spray formulations miaelson was 33:03 voluntarily discontinued by the manufacturer and current clinical practice guidelines now consider 33:10 calcetonin salamon as a second line or lower option for osteoporosis. While 33:15 behind bisphosphinates, dennism mob, uh, terrapeptide, the analesic effect of 33:21 calcetonin in bone pain, particularly in acute vitibbral, uh, compression 33:26 fractions from osteoporosis or pageantss disease may still provide a role for short-term use in these selected 33:32 patients. The mechanism of this pain relief is unclear, but may involve 33:38 effects of endorphin systems and/or direct actions on pathways. The history serves as an important reminder in 33:45 peptide medicine. Initial approval and early clinical use does not guarantee 33:50 long-term safety effects. Post marketing surveillance and poolled analysis of the clinical trial data can reveal adverse 33:58 effects that weren’t apparent in initial studies. It also underscores why newer 34:04 agents with better safety profiles um have largely replaced calcetonin in 34:10 clinical practice. So this is really an important thing. Not one thing stays the same forever. We have to change as we 34:18 identify new and better products as we identify problems and concerns. I will 34:24 always tell my patients if you are uncertain of taking a new drug which we 34:30 all should be wait five years. Within five years we are going to find the 34:36 problems that they didn’t find in the clinical studies. Remember, a lot of these clinical studies are small, small 34:43 groups, short periods of time. It’s expensive to do these trials. So, if you 34:49 wait for five years, in the first two to three years, you will see the problem start to emerge. And what are you going 34:55 to look for? You’re going to look for the the news um commercials from lawyers 35:02 suing a drug. And they will tell you what the problem is. and then you can decide, is this something that I want to 35:09 use or not. Don’t jump on bandwagon and be the first one to do this, especially 35:14 if you’re sensitive. You know, give it time so you can see exactly what’s going on. So, I’m going to end our show on 35:22 this and we are going to pick up on part three of peptide therapy in our next 35:28 segment where we’re going to talk about the investigational peptides and some 35:34 exciting things that are happening with that. So, I want to thank you for joining me today on Let’s Talk Wellness 35:39 Now. It’s always a pleasure having a conversation with you guys and I hope this brings value to you with what we’re 35:45 talking about. If you have ideas for topics that you want me to discuss, 35:51 please message us, you can share your comments on Facebook, you can email us, 35:58 um you can get a hold of us however you would like to share that. I do look at the comments below in the episodes as 36:04 well. So you can place your comments there. And once again, one of the best things you can do for me is like, 36:11 subscribe, and share so that we can spread the messages of what we’re doing. 36:16 I do this at no cost. I don’t make any money out of this. I do this as an 36:21 educational purpose for everybody else. I love doing it, but it really helps us 36:28 on the algorithms if you would be just willing to like, subscribe, and share. 36:33 So, thank you for spending your time with me. I know time is important.The post Episode 257 – Peptides for Sexual Wellness & Hormonal Health: PT-141, Growth Hormones, Bone Health & More! first appeared on Let's Talk Wellness Now.

In this episode of the IRH Clinician's Corner, Margaret Floyd Barry is joined by Dr. Anna Cabeca, who brings her expertise to unravel the complexities of female hormonal health, especially during the transition from perimenopause to menopause. Dr. Anna explains the hormonal shifts, discusses misunderstood symptoms like brain fog and mood swings, and shares her innovative Keto Green Method for metabolic and hormonal optimization.   In this interview, we discuss:   Foundational concepts for menopause and other hormonal transitions Traditional gynecological approaches vs.functional approaches Non-hormonal symptoms and the neuroendocrine connection Functional and dietary interventions (including Dr. Cabeca's Keto Green Method) Monitoring and customization of ketosis and alkalinity Hormone Replacement Therapy (HRT): When and How Dr. Anna's practitioner training program The Clinician's Corner is brought to you by the Institute of Restorative Health. Follow us: https://www.instagram.com/instituteofrestorativehealth/   Connect with Dr. Anna Cabeca Website: http://dranna.com or https://drannacabeca.com Facebook: https://www.facebook.com/DrAnnaCabeca Instagram: https://www.instagram.com/thegirlfrienddoctor Tiktok: https://www.tiktok.com/@drannacabeca  LinkedIn: https://www.linkedin.com/in/drannacabeca/ Podcast: dranna.com/show YouTube: https://www.youtube.com/thegirlfrienddoctor   Magic Menopause Certification Course: http://dranna.com/certifyme Julva - free sample: https://drannacabeca.com/products/julva-trial-pack?uid=2&oid=1&affid=5508004   Timestamps:  00:00 Hormonal Balance for Women's Health 07:45 Early Hormonal Fluctuations Insight 13:33 "Keto Green Diet for Women" 20:06 Ketosis Testing Tools Overview 25:56 Healing Through Balanced Nutrition 30:26 Prioritizing Oxytocin for Well-Being 35:19 "Keto, Uric Acid, and Health" 39:05 "Magic Menopause Program Benefits" 43:51 Holistic Health Tools & Balance 49:59 Magic Menopause Coaching Certification 55:59 Hormone Therapy for Sexual Health 59:43 Empowering the Body to Heal Speaker bio:  Anna Cabeca, DO, OBGYN, FACOG, is best selling author of The Hormone Fix and Keto-Green 16 and MenuPause. Dr. Anna is triple-board certified and a fellow of gynecology and obstetrics, integrative medicine, and anti-aging and regenerative medicine. She holds special certifications in functional medicine, sexual health, and bioidentical hormone replacement therapy.    She lectures frequently on those topics and shares the secret behind the ebb and flow of intimacy as she demystifies the fascinating hormonal changes over time. She will help you discover how the "love hormone", Oxytocin can breathe life into your relationship, and how Cortisol can take it away - and how the delicate balancing act of those hormones can reignite your libido and support a healthy relationship, most importantly the one you have with yourself. She is sassy, blunt, speaks from the heart and has a wonderful sense of humor, and this is why we call her The Girlfriend Doctor, because everyone needs a friend like her!    She has personally developed natural products to help women balance hormones and thrive through menopause including the highly acclaimed Julva® cream for the vulva and MightyMaca® Plus, a powerful superfood blend. She lives in Dallas with her daughters, horses and dogs.   Keywords:  menopause, perimenopause, hormone replacement therapy, progesterone, estrogen, DHEA, pregnenolone, neuroendocrine symptoms, insulin resistance, inflammation, adrenal health, SSRI, PMS, brain fog, ketogenic diet, Keto Green method, alkalizing foods, intermittent fasting, functional medicine, lab testing, lipid panel, FSH, uric acid, Mighty Maca, Julva cream, oxytocin, vitamin D, cardiovascular risk markers, women's health, restorative health Disclaimer: The views expressed in the IRH Clinician's Corner series are those of the individual speakers and interviewees, and do not necessarily reflect the views of the Institute of Restorative Health, LLC. The Institute of Restorative Health, LLC does not specifically endorse or approve of any of the information or opinions expressed in the IRH Clinician's Corner series. The information and opinions expressed in the IRH Clinician's Corner series are for educational purposes only and should not be construed as medical advice. If you have any medical concerns, please consult with a qualified healthcare professional. The Institute of Restorative Health, LLC is not liable for any damages or injuries that may result from the use of the information or opinions expressed in the IRH Clinician's Corner series. By viewing or listening to this information, you agree to hold the Institute of Restorative Health, LLC harmless from any and all claims, demands, and causes of action arising out of or in connection with your participation. Thank you for your understanding.  

Perimenopause is something the vast majority of women will experience and yet so many of us feel blindsided by it. I'm Dr. Jenny and in this episode, I talk about why perimenopause often isn't discussed in conventional medical appointments and why so many women are left hearing about it through social media instead of their doctor's office. Menopause is diagnosable. It shows up clearly on blood work. Perimenopause? Not so much. The 5–15 years before menopause can feel like a hormone roller coaster: Exhaustion Brain fog Night sweats and hot flashes Mood swings Irregular cycles Low libido Weight changes Feeling like you're "losing your mind" Here's the truth: If you feel like you're on a roller coaster, it's because your hormones are on a roller coaster. In this episode, I break down: Why adrenal health (your stress response system) is the foundation of hormone balance How chronic stress impacts DHEA and testosterone (hello brain fog and low libido) Why blood work can miss perimenopausal shifts How estrogen processing in the liver and gut plays a massive role in symptoms Why progesterone often declines first and what that means for sleep and mood How comprehensive testing (like the DUTCH test) gives us a real map instead of a single snapshot Most importantly, I explain how you can take your power back. We created a FREE Perimenopause Mini Podcast Series to help you understand: What actually is perimenopause (and what isn't) Why symptoms show up years before menopause What works, what doesn't How to get to the root cause of your symptoms quickly Listen to the FREE perimenopause series here: https://dr-beth-westie.mykajabi.com/perimenopause-3

Our hormones are essential to our mental and physical health, yet we often don't understand (or we minimize) the key role hormones play in fostering our wellbeing. And to make matters worse, many--or dare I say most – medical practitioners are not given adequate training when it comes to understanding the role hormones play in the health of our bones, heart, muscles, and brain. And when our bodily systems are not functioning well – whether we're experiencing issues such as a lack of focus, sleep disruption, weight gain, or low libido – our mental health can be deeply affected. Today, I'm joined by a top medical expert, Carrie Levine, who will help us discover key components of HRT (hormone replacement therapy) and so much more. Topics discussed include mental heath, depression, psychotherapy, support, physical health, hormones, HRT, hormone replacement therapy, estrogen, progesterone, progestin, DHEA, HPA Axis, cortisol, stress, stress management, exercise, resistance training, weight training, carbohydrates, protein, testosterone, Women's Health Initiative, menopause, perimenopause, post-menopause, relationships, A1C, blood glucose, sex, and libido. Please note that this episode contains sensitive material; listener discretion is advised. Note: If you or someone you know needs immediate support, please call your emergency services. In the US, 24/7 help is available by calling "911," "988" (Suicide and Crisis Hotline), or SAMSA (Substance Abuse and Mental Health Services Administration) at 1-800-662-HELP (4357). As applicable, additional resources may be provided in the show notes. Non-Emergency Online Mental Health Information:https://www.nami.org/support-education/nami-helpline/https://odphp.health.gov/myhealthfinder/healthy-living/mental-health-and-relationships IMPORTANT DISCLAIMER: No expert is offering medical or psychological direction or advice; the content is purely informational in nature. Please consult your physician or healthcare provider before undertaking any new regimen or procedure.https://www.nami.org/support-education/nami-helpline/Connect with Dr. Carla Manly:Website: https://www.drcarlamanly.comInstagram: https://www.instagram.com/drcarlamanly/Twitter: https://www.twitter.com/drcarlamanly/Facebook: https://www.facebook.com/drcarlamanlyLinkedIn: https://www.linkedin.com/in/carla-marie-manly-8682362b/YouTube: https://www.youtube.com/@dr_carlamanly_imperfect_loveTikTok: https://www.tiktok.com/@dr_carla_manlyBooks by Dr. Carla Manly:Joy From Fear: Create the Life of Your Dreams by Making Fear Your Friend Date Smart: Transform Your Relationships and Love FearlesslyAging Joyfully: A Woman's Guide to Optimal Health, Relationships, and Fulfillment for Her 50s and BeyondThe Joy of Imperfect Love: The Art of Creating Healthy, Securely Attached RelationshipsImperfect Love Relationship & Oracle Card Deck by Dr. Carla Manly:EtsyAmazonConnect with Carrie:Website: https://carrielevine.com/Instagram: https://www.instagram.com/carrielevine.cnm/Facebook: https://www.facebook.com/CarrieLevine.cnm/LinkedIn: https://www.linkedin.com/in/carrie-levine-cnm/Love the show? Subscribe, rate, review, and share! https://drcarlamanly.com/

In this Your Health University episode, Jamie sits down with Nurse Practitioner, Brooke Howard, President of Clinical Operations, to talk about Biote, wellness, and bioidentical hormone optimization—and why it has been life-changing for both of them. Brooke shares how a trusted colleague pushed her to look deeper when she was exhausted, gaining weight, and “holding it together by a thread.” Jamie opens up about anxiety, ADD medication, and how feeling hormonally balanced gave him the confidence to step into a new chapter. This conversation is for anyone who feels “off,” has been told their labs are “normal,” and wants to explore a more complete picture of wellness. www.YourHealth.Org

Midlife can feel like your body suddenly changed the rules. The supplements that once boosted energy, hair growth, and metabolism might now be causing bloating, acne, brittle hair, belly fat, dry skin, hormone imbalance, and even abnormal lab results. In this episode, Chalene breaks down the popular supplements many women over 40 are still taking that could be quietly sabotaging their health, thyroid labs, skin barrier, bone density, and hormones. If you're navigating perimenopause or menopause and wondering why you don't feel like yourself anymore, this conversation will challenge what you think you "should" be taking. This is not about fear. It's about testing, not guessing, and making smarter choices in midlife. Check out this video on YouTube

In this episode, Dr. Fiona Lovely sits down with the renowned "Queen of Hormones," Dr. Carrie Jones, for a candid and wide-ranging conversation that cuts through the noise surrounding women's health at midlife. As a Naturopathic Physician with advanced degrees in public health and endocrinology, Dr. Jones brings over two decades of clinical experience to the discussion, offering listeners a masterclass in understanding their own physiology. The conversation explores why Gen X and elder millennial women are uniquely positioned to challenge the status quo when it comes to perimenopause and menopause. Dr. Jones explains that hormone therapy isn't a one-size-fits-all solution—it's a nuanced process that requires individualized attention, much like finding the perfect skincare routine. She addresses the moving target of hormone optimization, explaining how factors like skin thickness, lifestyle, and even climate can affect absorption and efficacy. Listeners will gain valuable insight into the distinction between early and late perimenopause, why progesterone typically declines first, and how estradiol influences everything from serotonin production to joint health. Dr. Jones also sheds light on the critical connection between declining hormones and mental health, explaining why so many women are misdiagnosed and prescribed antidepressants when what they truly need is hormone support. Throughout the episode, both hosts emphasize the importance of testing to understand what's actually happening under the hood rather than relying on guesswork. This is an empowering discussion about taking ownership of your health journey and refusing to accept inadequate answers. Find Dr. Carrie Jones here: Instagram: @dr.carriejones Titkok: @dr.carriejones Youtube: https://www.youtube.com/@drcarriejones Spotify: https://open.spotify.com/show/0QMOu9ma6Xljf5omizAhNz?si=4dbaaf83a8cf4508 Apple Podcast: https://podcasts.apple.com/us/podcast/hello-hormones-with-dr-carrie-jones/id1813934931  Website: www.drcarriejones.com    Thank you to our sponsors for this episode: Berkeley Life is a health brand that helps women feel vibrant by addressing the crucial role nitric oxide and circulation play in daily wellness, especially around menopause. If you're navigating perimenopause and want to support your cardiovascular health and your menopause transition proactively, Berkeley Life's Menopause and Heart Health support is designed exactly for this moment. You can learn more and explore their supplements at BerkeleyLife.com and get 20% off your first order (use code LOVELY) If you're noticing fine lines, wrinkles, or sagging skin — thanks menopause —ugh, me too. Menopause can deplete your skin's collagen, speeding up aging. But here's the game-changer: Vitali Skincare has built its entire line on the power of GHK-Cu copper peptides — a proven ingredient that signals your skin's stem cells to produce new, healthy collagen. Head to vitaliskincare.com and use the code LOVELY at checkout for 20% off.  Check out their brand new exosomes product - Vita.  It's unlike anything else I have used leaving my skin smoother, tighter and glowing.   Stop tolerating menopause discomfort. If dryness and painful sex feel like your new normal, it's not just aging—it's estrogen loss. Velvet V, created by hormone expert Karen Martel, is a clean, prescription-free vaginal moisturizer packed with estriol and DHEA to restore moisture, thicken tissue, and improve sensation. Experience real relief and more confidence in just weeks. No doctor visit required!  Go to midlifesolutions.org and use code LOVELY for 10% off your first order. Because glowing skin and great sex shouldn't be optional in midlife.   Dr. Fiona Lovely is a longevity, health and wellness expert with specialties in menopause medicine, functional neurology and functional medicine.  She is speaking to the topics of women's health around perimenopause and menopause. How to work with Dr. Lovely: We get many requests for this info, so here it is!  First off, thank you for listening to the NYMM podcast.  It's because of your support, we can continue to dispense this information.❤️ Follow Dr. Lovely on IG and TikTok: @drfionalovely Follow the podcast on Facebook:  www.facebook.com/@notyourmothersmenopausepodcast There are resources available on our website:  www.drlovely.com Please sign up for our newsletter - Fiona's Friday Favourites!  This is where we make the first announcements, share course offerings, drop new episodes,  blog posts and the coveted 'Fiona's Favourites' column, etc.   drlovely.com Finally, a humble request:  If you love the podcast, please leave us a review!  It helps more people find useful info for a challenging time: https://podcasts.apple.com/ca/podcast/not-your-mothers-menopause-with-dr-fiona-lovely/id1097326296  Please scroll to the bottom of the page to leave a review.  Thank you! 

"Since the 80s, we've been brainwashed to believe that eggs are bad for us, butter is bad for us, dairy is bad for us, red meat is bad for us. And it's just not true." If you've been told your cholesterol is "too high"... if you're on a statin drug and wondering if it's actually helping... if you care about preventing heart disease instead of just managing it... this episode is your wake-up call. It's Heart Health Month, and Dr. Terri is cutting through decades of misinformation to reveal what's REALLY driving cardiovascular disease — and it's not cholesterol. From the gut-heart connection to the six hormones that could save your life, this is the heart health conversation your doctor probably isn't having with you. Here's the truth: "The highest gross revenue producing drug in the history of drugs — billions of dollars — and since they've come out in the 80s, cardiovascular disease rates and death from cardiovascular disease have actually gotten worse, not better." WHAT YOU'LL DISCOVER: → Why heart disease is a disease of INFLAMMATION, not cholesterol → The shocking truth about statin drugs — and why heart disease has gotten WORSE since the 80s → How cholesterol-lowering drugs are literally shrinking your brain (the brain is 70% cholesterol) → The connection between statins, insulin resistance, and Alzheimer's (now called Type 3 Diabetes) → Why "all disease begins in the gut" — Hippocrates said it 2,000 years ago and it's still true → How estradiol reduced cardiovascular disease progression by 50% in women who already had plaque → Why testosterone is powerfully protective for men's hearts (not just for energy and muscle) → The one organ that can't make its own T3 thyroid hormone — your heart → Why your "normal" lab ranges are based on a sick population (and what optimal ACTUALLY looks like) → The phone scrolling habit that's destroying your melatonin AND your heart health → The inverse relationship between cortisol and DHEA that's wrecking your cardiovascular system → The vitamin D level that triggers a 5x cancer risk and 160% increased cardiovascular disease risk → The 6 hormones you need optimized for true heart disease prevention This isn't about managing heart disease with more prescriptions. It's about understanding the root cause — inflammation — and optimizing the hormones your body needs to protect itself. YOUR ACTION STEPS: Get a deep-dive lipid panel (particle size, ApoA, ApoB), check your hormone levels, ask about a coronary artery calcium score, and focus on OPTIMAL — not just "normal." TIMESTAMPS: 0:00 - Intro: It's Heart Health Month 2:15 - Heart disease is NOT a cholesterol problem 4:20 - The statin drug soapbox: billions in revenue, worse outcomes 6:40 - How statins are connected to Alzheimer's and insulin resistance 7:55 - It all begins in the gut: inflammation and lipid polysaccharides 9:05 - The one statin study — and why it doesn't apply to everyone 10:20 - Estrogen: a powerfully protective anti-inflammatory molecule 11:25 - The study showing 50% reduction in plaque progression with estrogen 14:05 - Testosterone: protective for cardiovascular disease in men 14:45 - Thyroid: the heart can't make its own T3 16:15 - Why "normal" lab ranges are based on sick populations 17:15 - Optimal Free T3 levels and what pediatric data actually shows 17:50 - Melatonin: the hormone you're destroying with your phone 19:10 - DHEA: the cortisol-DHEA inverse relationship 20:25 - Vitamin D: the hormone-like molecule with massive cardiovascular impact 21:20 - Recap: The 6 hormones for heart disease prevention ---- The Dr. Terri Show is presented by EVEXIAS Health Solutions. For more, visit: https://www.evexias.com ---- Connect with Dr. Terri DeNeui, DNP:

Perimenopause libido dropping after 40? If sex feels different—lower desire, more dryness, shorter fuse, less connection—your hormones (not your relationship) may be the missing piece. In this episode of Ask a Sex Therapist, Heather Shannon talks with board-certified OB-GYN + functional/integrative hormone expert Dr. Tara Scott about the most common hormone shifts that impact women's sex drive across postpartum, perimenopause, and menopause—and why women's desire is often more “Goldilocks” than linear (too little or too much estrogen can cause problems).You'll learn how hormone testing can be interpreted when timing is right, why blood levels don't always match what's happening in your tissues, and how chronic stress can quietly deplete DHEA and testosterone (even in your 30s and 40s). Dr. Scott also breaks down practical, realistic ways to support hormone health—movement, food quality, sleep, stress tools, and reducing endocrine disruptors—without trying to overhaul your entire life overnight. If you're dealing with low libido, vaginal dryness, painful sex, fatigue, sleep changes, or irritability, this conversation will help you understand what's normal, what's treatable, and how to advocate for better care.Chapters00:00 Introduction to Hormonal Health01:22 Understanding Hormonal Shifts Throughout Life03:41 Differences in Male and Female Libido14:00 Personalizing Hormonal Treatment28:46 The Impact of Lifestyle on Hormonal BalanceWant to address the emotional and psychological factors blocking your sex life? Request a free consultation for coaching/therapy with Heather or a member of her team here: Booking A Consultation With The Right PersonLearn more about our guest Dr. Tara Scott at:Website - https://drtarascott.com/YouTube - https://www.youtube.com/@TaraScottMDThis podcast uses the following third-party services for analysis: Podtrac - https://analytics.podtrac.com/privacy-policy-gdrp

You've heard of burnout. But what if the real crisis starts long before the breaking point? In this short opener, host Stacie introduces allostatic load — the scientific term for the cumulative "wear and tear" the body accumulates under chronic, unresolved stress. It's not a bad week. It's what happens when the body never fully recovers, and the nervous system learns to treat survival mode as its new normal. Research shows women carry a disproportionate allostatic burden — driven not just by biology, but by the invisible labor, emotional weight, and systemic pressures that don't clock out at 5pm. And for leaders and HR professionals, this matters: what often looks like a performance problem in your workforce may actually be a health signal hiding in plain sight. This episode opens a series that follows allostatic load where it leads — into autoimmune disease, hormonal disruption, ADHD, and what it truly costs women, leaders, and organizations when we keep misreading the signal. Under 5 minutes. But it might change how you see everything else. Stacie Origins of the Term The concept of allostasis — meaning "stability through change" — was first introduced by neurobiologist Peter Sterling and epidemiologist Joseph Eyer in 1988 to describe how the brain dynamically recalibrates internal physiological systems in anticipation of environmental demands, rather than simply reacting to them. Building on this foundation, neuroscientist Bruce McEwen and physiologist Eliot Stellar coined the term allostatic load in 1993, defining it as the cumulative physiological "wear and tear" the body experiences when allostatic systems are chronically activated, fail to shut off, or never perform normally. McEwen later described this as "the price of adaptation" — the physiological cost the body pays for sustained attempts to manage chronic stress. The Biological Cascade: What Happens in the Body When the brain perceives a stressor — real or anticipated — it activates two primary physiological systems: the sympathetic-adrenal-medullary (SAM) axis, which releases catecholamines (adrenaline, noradrenaline), and the hypothalamic-pituitary-adrenal (HPA) axis, which releases glucocorticoids, primarily cortisol. In the short term, these responses are adaptive and protective. However, under conditions of chronic, unresolved stress, this cascade remains activated. Over time, the brain and organ systems undergo measurable physiological changes: ↑  Elevated cortisol, epinephrine, and norepinephrine (neuroendocrine markers) ↑  Elevated inflammatory markers: C-reactive protein (CRP), interleukin-6 (IL-6), fibrinogen ↑  Dysregulated blood pressure, lipid levels, glycated hemoglobin (metabolic markers) ↓  DHEA (dehydroepiandrosterone) — the protective counterpart to cortisol A 2001 landmark study using the MacArthur Studies of Successful Aging demonstrated that higher allostatic load scores at baseline were significantly associated with increased 7-year mortality risk and declines in both cognitive and physical functioning. A comprehensive 2020 systematic review of 267 studies confirmed that allostatic load and allostatic overload are robustly associated with poorer physical and mental health outcomes across a wide range of conditions.

The FBI Claims There Were No Sex Rings in Epstein Files | Did Trump and Homan Deliver Properly on Deportations | SEC and SDNY Drain Stock Market Entrepreneur and Investors | Dr. Mark Sherwood, Michael CastilleroFollow BBN on X: @dloydfaulk @bf_frontlineOn pickax.com: @dlloydfaulk, @BFBroadcastingOn Telegram: https://t.me/BFBroadcastingOn Rumble: BFBroadcastingSupport independent media:- Visit https://sherwood.tv/battlefront and discover the new Kingdom Fuel, Kingdom Kandy, and Kingdom Cup. Also, choose preventative health plans from the Functional Medical Institute.- New items are arriving like the MyPillow 2.0 and MyMattress Topper 2.0. Save up to 66% now with the code: Battle. Visit https://mypillow.com/battle and https://mystore.com or call (800) 559-7535.- Join a true America First mobile network where righteous principles matter and your values are represented at https://patriotmobile.com/battlefront⁃ Defy the ordinary and drink the brew of the defiant with the code BATTLE at https://supermassiveblackcoffee.com .-B17 can prevent abnormal cell growth within the body. Starting at 3 apricot seeds per day you can begin to rid your body of abnormal cells such as tumors according to founder John Richardson. Big Pharma has shut down these treatments. You can get it now at https://rncstore.com/battle and using the code BATTLE you get 10% off. Begin your treatment today.- Unlock the powerful natural antibiotic and healing properties of Micronic Silver at https://www.micronicsilver.com/?af=921EY- As legacy media continues to decline, I believe yourNEWS.com is poised to become the future of mainstream media. This is why I'm involved, and why my content is featured on the platform. yourNEWS.com is by the people, for the people, and I believe ownership should reflect that. They're currently conducting an Equity Crowdfunding campaign, allowing you to invest with as little as $200 or substantially more if you prefer. If you support this mission, I encourage you to click the link below, watch the video, and consider making an investment. I personally know the CEO and believe strongly in his vision, which is why I'm also a shareholder. https://issuanceexpress.com/nico-regcf/

Dr. Natalie Crawford, board-certified OB-GYN and REI, answers your fertility questions.1. Husband has low sperm morphology. IUI didn't work—how much does morphology really matter? 2. After 5 losses and 2 years trying, she's scared to do IVF with genetic testing. What are her next steps? 3. Low AMH, 3 miscarriages, 3 IUIs, 1 IVF—doctor recommended DHEA without checking testosterone. Could her high testosterone have affected IVF? 4. Thoughts on phone-based fertility monitors for someone with PCOS? Are urine hormone measurements reliable? 5. Miscarriage 6 months ago, now trying again. Husband has low testosterone—what safe options or natural approaches can help? Pre-order Dr. Crawford's debut book, The Fertility Formula, now! ⁠⁠⁠⁠https://www.nataliecrawfordmd.com/book⁠⁠⁠⁠ Want your questions answered on the next episode? ⁠Ask them here!⁠ ⁠⁠https://www.nataliecrawfordmd.com/qa-submissions⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

In this empowering episode, Dr. Anna Cabeca, The Girlfriend Doctor, sits down with internationally respected gynecologist and menopause expert Dr. Maria Sophocles to break the silence around vaginal and vulvar atrophy, hormonal shifts, and declining intimacy in midlife. They explore why pain, dryness, and loss of desire are often normalized—and how this fuels what Dr. Sophocles calls "The Bedroom Gap." You'll learn how hormones, anatomy, stress, and communication impact pleasure, plus evidence-based strategies to restore comfort, confidence, and connection at any age. Menopause is natural. Suffering is optional—and pleasure is your birthright.   ⏱️ Key Timestamps 00:00 – Welcome to The Girlfriend Doctor Show 01:45 – Why sexual medicine is missing from OB-GYN training 04:20 – What The Bedroom Gap really means 07:15 – Why women's sexual pain is often normalized 10:00 – The ABCs of sexual health: Acceptance, Being present, Communication 19:25 – Hormones, dryness, pain & loss of desire in midlife 23:10 – Vulvar anatomy & early signs women shouldn't ignore 28:15 – DHEA, estrogen & testosterone for tissue health 42:30 – Practical strategies to close the bedroom gap 58:00 – Reclaiming intimacy, confidence & pleasure at any age  

DHEA was first identified in 1931 by Dr. Adolf Butenandt, who was awarded the Nobel Prize for Chemistry in 1939. Frequently called “the anti-aging hormone”, DHEA is a base for more than 50 hormones that are smaller or more specific carbon chain molecules in human biochemistry. As a precursor for all estrogenic and androgenic hormones, humans make DHEA naturally from birth.It's now well established that chronic stress leads to an out-pouring of cortisol and with that, a gradual depletion of DHEA. DHEA is a prohormone – a natural building block for hormones our bodies make.Over time, this hormonal imbalance can lead to brain fog, thinning bones, weight gain, low sex drive and poor Immune function.Maintaining proper DHEA levels in the body is important to your overall health and may lead to Increased energy, enhanced mood and focus, sound sleep, and better letting skin.Guest: Joining us today is Hugh Woodward, He is the President of Health2Go, Inc the makers of Twist 25 DHEA cream. Hugh is a subject matter expert on DHEA dedicating nearly 2 decades of his life studying the medical research about it, and starting a company to research, develop the safest most effective DHEA supplement that can be made and distributing it.In 2007 Mr. Woodward started Health2Go, Inc. to research and develop leading edge anti-aging and wellness products and bring them to people conveniently and cost effectively.Quality matters when supplementing with DHEA.Twist 25 DHEA Cream puts exactly what the body makes naturally – bioidentical DHEA -in the skin, where the body processes DHEA.  As a base building block for hormones, DHEA gives the body a key foundation it uses to make hormones, (especially the androgens our feel-good hormones.)Visit Twist25.com to learn more and order online. Or call 888-489-4782 that's888-489-4782. Look your best feel your best with Twist 25 DHEA creamthat's twist25.comListeners can save 10% OFF using the code: forever at checkout.Helpful Articles

Women with psoriasis consistently show lower progesterone and DHEA, two hormones that normally quiet inflammation, making flare-ups stronger and more frequent Estrogen dominance — where estrogen feels too strong relative to progesterone — heightens immune reactivity and explains why symptoms worsen before your period, after childbirth and during menopause Intracellular estrogen, not blood estrogen, drives inflammation in psoriatic skin, which is why your labs can look "normal" even when your symptoms intensify Long-term hormone replacement therapy increases psoriasis risk by overstimulating inflammatory pathways, especially in post-menopausal women whose hormones are already shifting You can ease flare patterns by supporting progesterone and DHEA, eliminating estrogen-mimicking triggers, avoiding seed oils, optimizing vitamin D and reducing stress-related hormonal strain

Welcome back to our weekend Cabral HouseCall shows!   This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track!   Check out today's questions:    Savanna: Hi Dr Cabral. My daughter was diagnosed with PANDAS through blood work after i noticed âlot of behavioral regression. She has also been recently diagnosed with level one, high functioning autism. I feel like a detective trying to figure out whats causing these flares. Some months she has seemingly zero symptoms. Then something sets it off (of course the sickness is one culprit causing the PANDAS) but over laps into autistic behaviors. I guess Im trying to ask for help in this mystery of triggers. Also suggestions of where to start to boost her immune system to prevent the sickness in the first place. I feel so discouraged as a parent not knowing how to help my child and watching her suffer. Just as I think I find a good supplement, it stops working. Such as valerian. We were using it as one calming aid and it worked for months and now all the sudden doesnt seem to be doing anything. This has happened with supplements in the past. I did your heavy metal detox and parasite cleanse with her a few years ago. Thnx                                                                                         Yvonne: As a post-menopausal woman, according to my gynecologist, I am not eligible for bioidentical hormones.  Is it ok to take DHEA after a certain age due to ongoing menopause symptoms of facial aging, insomnia, vaginal dryness etc and, if so, what dosage?                                                                            Emily: Hi Dr Cabral, I am currently working through an autoimmune face rash. I am working with a local integrative functional doctor who is recommending low dose naltrexone, and many other items. What are your thoughts on LDN? Harmful, helpful? How long should one stay on it?     Laura: Hi, I'm interested in what ingredients are ok in supplements and food.. for example, hydroxypropyl methylcellulose in baking or in supplements, different gums, which additives are ok? Thank you     Sheena: HI Dr.C! Hope you and your team are well. I'm a 45 year old in perimenopause and would like to prevent osteoporosis. Could you give me some advice on what's the best way to do this? I take foundational level 3 plus added vitamin D, magnesium, zinc and vitamin b. complex. I'm not not taking any calcium supplements except from my multi. Is this a prob? Do I need a special protocol for perimenopause support and osteo? Any advice and recommendations will be appreciated! thank you!     Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions!      - - - Show Notes and Resources: StephenCabral.com/3641 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

Broadcast from KSQD, Santa Cruz on 1-22-2026: An emailer from Canada asks about long-term Remicade (infliximab) use for her 16-year-old daughter's ulcerative colitis. Dr. Dawn explains the drug blocks tumor necrosis factor, which stops autoimmune attacks but also weakens infection defense—increasing risk of fungal infections, tuberculosis, and after about 10 years, slightly elevated blood cancer risk. She recommends the daughter practice good hygiene and mask in high-risk settings. For achieving full remission, she suggests vitamin D levels around 75-80, DHEA supplementation, strict gluten avoidance due to its pro-inflammatory effects, and working with a certified functional medicine practitioner to heal the gut and potentially withdraw medication. Dr. Dawn presents a case study of a 27-year-old woman with progressive weakness, pins-and-needles sensations, and impaired balance. Despite normal B12 blood levels, elevated homocysteine and methylmalonic acid revealed functional B12 deficiency from using 20-30 nitrous oxide whippets daily. Nitrous oxide oxidizes the cobalt atom in methylcobalamin, permanently inactivating the enzyme needed for myelin sheath maintenance. Treatment requires months of daily B12 injections with recovery taking up to 84 weeks. She warns that nitrous oxide also interacts dangerously with Viagra-type drugs (causing dangerous blood pressure drops), methotrexate, stimulants, hallucinogens, and respiratory depressants. She describes Canadian researchers developing a miniaturized 3D printer for vocal cord repair. After removing nodules that cause hoarseness, the device prints hydrogel along the wound to create a flat surface preventing keloid-like regrowth, rather like spackling a wall before healing occurs underneath. Dr. Dawn discusses lipoprotein(a), written as Lap(a), a genetic cardiovascular risk factor discovered in the 1960s. This relative of LDL carries a protein that promotes blood clots, thus raising heart attack and stroke risks. In a recent large survey, only about 14% of people have been screened despite its significance. New drugs like pelicarsin can reduce Lp(a) levels up to 80%,trials underway to confirm a benefit of reduced cardiac events. She notes tennis star Arthur Ashe had high Lp(a) contributing to his coagulopathy. A natural option is already available. She recommends lumbrokinase, derived from earthworms and used in traditional Chinese medicine, as an existing treatment that combats high Lp(a) and counteracts its procoagulant effects. The product Boluoke is commercially available, offering an alternative to high-dose niacin which causes intolerable flushing and diarrhea. Dr. Dawn reports research finding people with anxiety disorders have 8% lower choline levels in brain regions regulating emotion. Increasing choline could help. Choline sources include eggs (two eggs provide 300mg of the 500mg daily choline need), organ meats, salmon, soybeans, and lecithin supplements.

"From GABA to DHEA, why are so many things not available in the UK?"Thanks for listening to Age Well with Dr Sophie Shotter!Find out more about Dr Sophie by heading to https://drsophieshotter.com/Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en*****This show is sponsored by Nooānce Paris - offering award winning premium skincare and next-generation LED masks.Head to https://www.nooance-paris.com/ – and get 15% off with the code DRSOPHIE*****This show is sponsored by Microbz – harnessing good bacteria directly from UK soil which means more diversity and at least 15 strains of good bacteria in every shot.Buy now at https://microbz.co.uk/ and use the discount code SOPHIE20 for 20% off.*****This show is sponsored by Primeadine – a clean, natural, and science-backed spermidine supplement – proven to up-regulate a range of health markers.Buy now at https://oxfordhealthspan.com/ and use the discount code DRSOPHIE for 20% off.*****This podcast was produced by https://thepodcastpeople.co/Co-host: https://fionamattesini.co.uk/The content in this podcast is for general information purposes only and is not meant to serve as medical advice or to replace or substitute advice given by, or consultation with, your doctor or any other healthcare professional. Please contact your healthcare provider if you have any questions or concerns about your health. Dr Sophie Shotter, her company and any employees or representatives are not liable for any claims arising out of or in connection with this podcast.Mentioned in this episode:This show is sponsored by NOOANCE Paris - offering next-gen LED masks and premium skincare with powerful, precisely dosed active ingredients. Buy now at https://www.nooance-paris.com and use the discount code DRSOPHIE for 15% off.This show is sponsored by Primeadine – a clean, natural, and science-backed spermidine supplement – proven to up-regulate a range of health markers. Buy now at https://oxfordhealthspan.com/ and use the discount code DRSOPHIE for 20% off. This show is sponsored by Microbz – harnessing good bacteria directly from UK soil which means more diversity and at least 15 strains of good bacteria in every shot. Buy now at https://microbz.co.uk/ and use the discount code SOPHIE20 for 20% off.

Send me a text! I'd LOVE to hear your feedback on this episode!I break the silence around vaginal atrophy, share the research behind local estrogen, and explain why systemic HRT often misses this common, under-treated problem. I compare a couple of creams, DHEA, and low-dose estradiol inserts, and share practical steps for personalized care.• defining vaginal atrophy and why it accelerates after menopause• how estrogen loss drives dryness, pain, urgency, and infections• why systemic HRT often fails to restore vaginal tissue• estriol versus estradiol: forms, dosing, and convenience• safety and systemic absorption with low-dose vaginal estrogen• UTI risk reduction and pelvic floor benefits• off-label DHEA and testosterone: where they may fit• finding knowledgeable clinicians and tailoring therapy• personal outcomes with estradiol inserts and symptom reliefPlease if this helps, I would love for you to share this, leave me some comments, likes, and share this with a friend.  And always remember when you rate, review, subscribe, you help to support my content and help me to keep going and bring these conversations to you each and every week.If you have topics or would love to open up a discussion or comments you'd like for me to read on one of my podcast episodes, please email me at sandy@sandyknutrition.ca.Also be sure to follow me on all of my social media platforms - Instagram, Facebook, TikTok, Threads, Lemon8, YouTube - it's sandyknutrition everywhere!Support the showPlease rate & review my podcast with a few kind words on Apple or Spotify. Subscribe wherever you listen, share this episode with a friend, and follow me below. This truly gives back & helps me keep bringing amazing guests & topics every week.Instagram: https://www.instagram.com/sandyknutrition/Facebook Page: https://www.facebook.com/sandyknutritionTikTok: https://www.tiktok.com/@sandyknutritionYouTube: https://www.youtube.com/channel/UCIh48ov-SgbSUXsVeLL2qAgRumble: https://rumble.com/c/c-5461001Linkedin: https://www.linkedin.com/in/sandyknutrition/Substack: https://sandykruse.substack.com/Podcast Website: https://sandykruse.ca

In this episode, Prof Chapman draws on nearly 40 years of IVF experience to unpack the growing use of so-called IVF “add-ons” or adjuvants. He explains why many treatments offered after failed cycles—such as CoQ10, DHEA, and testosterone—are not supported by strong scientific evidence, despite their popularity. Prof Chapman also clarifies real IVF success rates over multiple cycles, challenges misleading claims, and offers a grounded perspective on where hope truly comes from in fertility treatment. Explore the 'Prof. Michael Chapman - The IVF Journey' Facebook Page, your reliable destination for cutting-edge insights and guidance within the realm of In Vitro Fertilization (IVF). Don't miss out on the IVF Journey podcast; stay informed with the latest episode updates. Tune in for expert discussions and valuable information on navigating the intricate path of IVF.

DHEA is one of the most commonly self-prescribed hormones—and one of the most misunderstood. In this episode of The Health Revival Show, we break down the real difference between DHEA vs DHEA-S, how cortisol patterns impact adrenal health, and why taking DHEA without testing can worsen acne, anxiety, estrogen dominance, and fatigue. We cover when DHEA supplementation actually helps, when it hurts, how stress, under-eating, over-training, menopause, and chronic illness affect adrenal output—and what to fix before reaching for hormones. If you're dealing with fatigue, low libido, stubborn weight gain, hormone imbalance, or burnout… this episode is a must-listen. Labs Decoded - Free 5 Day Webinar Lunch-n-Learn Reserve Your Spot Now A free 5-day Lunch & Learn series teaching you how to understand your lab work through a functional medicine lens — so symptoms finally make sense. *** CONNECT:

Feeling wiped after workouts that used to energize you? This episode breaks down the real reason exercise can start working against you. We dive into exercise intolerance, mitochondrial dysfunction, chronic stress, cortisol, DHEA, hormone shifts, long viral activation, and why “pushing through” often backfires—especially for women in high-stress seasons or perimenopause. Learn how fatigue, soreness, inflammation, poor recovery, and stalled progress are signs your body needs support, not more grind. If your labs look “normal” but your body feels broken, this conversation connects the dots. Labs Decoded - Free 5 Day Webinar Lunch-n-Learn Reserve Your Spot Now A free 5-day Lunch & Learn series teaching you how to understand your lab work through a functional medicine lens — so symptoms finally make sense. *** CONNECT:

Broadcast from KSQD, Santa Cruz on 1-08-2026: Dr. Dawn concludes her 2025 medical advances recap, noting that while GLP-1 weight loss drugs showed unexpected benefits for addiction, schizophrenia, and dementia risk, Novo Nordisk recently reported semaglutide had no effect on cognition in people with existing dementia or mild cognitive impairment. She describes the first successful human bladder transplant performed on May 4th. The 41-year-old recipient received both kidney and bladder due to the bladder's complex blood vessel network. Surgeons practiced on cadavers with active circulation before achieving success, opening pathways for future bladder-only transplants for the 84,000 Americans diagnosed with bladder cancer annually. An emailer follows up about purslane for cognitive health. Dr. Dawn reviewed the referenced studies and found neither actually supported claims about purslane and cognition—one discussed the Lyon Heart Study's Mediterranean diet, the other described antioxidant properties. She cautions listeners that websites citing "scientifically proven" claims often reference articles that don't support their assertions. An emailer asks about statin alternatives after developing severe muscle pain on both atorvastatin and rosuvastatin. Dr. Dawn suggests he shouldn't be on statins given his classic adverse reaction. She recommends ezetimibe plus oat bran for cholesterol, metformin for his elevated triglycerides indicating insulin resistance, and checking LDL particle size and inflammation markers. She emphasizes that cholesterol is a risk factor, not a disease, and treating 50 low-risk people for 10 years prevents only one heart attack. A caller discusses plaque formation theory, comparing it to calluses. Dr. Dawn explains Linus Pauling's similar hypothesis that plaque forms at vessel bifurcations to protect against turbulent blood flow damage. She warns against driving total cholesterol below 130, as it disrupts steroid hormone production. The caller shares his mother's near-fatal rhabdomyolysis from statins—muscle breakdown releasing myoglobin that clogs kidneys—and criticizes data transfer failures between hospital systems. An emailer reports four UTIs in two months at age 79. Dr. Dawn questions whether all were true infections, since vaginal contamination causes false positives on dipstick tests. For confirmed UTIs, she recommends D-mannose and cranberry to prevent bacterial adhesion, post-void residual ultrasound to check for incomplete emptying, lactobacillus probiotics, and vaginal DHEA (Intrarosa) to restore mucosal thickness and disease resistance. Dr. Dawn describes Stanford's Phase III trial for dystrophic epidermolysis bullosa, where defective collagen-7 causes skin layers to separate at the slightest touch. Researchers take patient skin biopsies, use retroviruses to insert corrected genes, grow credit-card-sized skin grafts over 25 days, then suture them onto wounds. At 48 weeks, 65% of treated wounds fully healed versus 7% of controls. She reports a Stanford study showing premature babies who heard recordings of their mothers reading for 2 hours 40 minutes daily developed more mature white matter in language pathways. The left arcuate fasciculus showed greater development than controls, demonstrating how early auditory stimulation shapes brain circuitry even in NICU settings. Dr. Dawn concludes with tattoo safety concerns. Modern vivid inks contain compounds developed for car paint and printer toner, including azo dyes that break down into carcinogenic aromatic amines—especially during laser removal. Pigment particles migrate to lymph nodes and persist in macrophages, causing prolonged inflammation. She advises those with tattoos to avoid laser removal, wear sunscreen, practice lymphatic hygiene, and reconsider extensive new tattoos.

Send us a textEver feel wired but somehow exhausted, like your brain won't shut off even when your body begs for rest? We dive into the hidden physiological price of being everyone's go-to, especially for women in their 40s and 50s, and why chronic busyness silently derails sleep, mood, and metabolism. Drawing on real-world patient patterns, we connect the dots between nonstop demands and hormonal shifts that don't show up as “willpower problems” but as progesterone dips, low DHEA, cortisol swings, and sluggish thyroid conversion.We break down how the lizard brain flags late-night emails as danger, setting off survival mode that flattens your spark. You'll learn the lived signs of low progesterone—irritability, restless nights, pre-period sensitivity—and how adrenal depletion pulls resources away from calm and toward stress chemistry. We also unpack the cortisol and DHEA partnership, what happens when DHEA declines faster than age alone would predict, and the overlooked link between stress and poor T4-to-T3 thyroid conversion that produces brain fog, cold intolerance, brittle nails, hair shedding, constipation, and weight creep despite “doing everything right.”Most importantly, we map out a sustainable path back. Cycle intensity instead of grinding daily: swap some HIIT for walks, yoga, Pilates, mobility, or breath work to give adrenals a true break. Build protein-first mornings with healthy fats to stabilize blood sugar and support cortisol rhythms. Create real sleep boundaries by setting Do Not Disturb two hours before bed while allowing emergency contacts. Consider gentle adaptogens like ashwagandha, rhodiola, and holy basil, and move from guessing to clarity with targeted labs: DHEA-S, TSH with free T3 and free T4, and appropriately timed progesterone testing. You'll walk away with a practical, compassionate toolkit to protect energy, restore mood, and feel grounded again without abandoning the people and work you love.Start the free Harmonize Your Energy Workshop and destress during this 90-minute workshop:Harmonize Your EnergyIf this helped, follow the show, share it with a friend who needs permission to slow down, and leave a quick review so others can find it. Your next step: set your phone's nighttime mode tonight and tell us how your wind-down changes your sleep.Welcome to the Art of Healing Podcast community. This podcast is devoted to helping you find what works on your journey to health and wellness. This podcast is devoted to providing information on many healing modalities. Learn more about:ReikiFunctional MedicineMeditationEnergy Healingand more!Learn more about Dr. Charlyce here. Never miss an episode of Art of Healing Podcast...the podcast devoted to helping you heal your mind, body and spirit.Sign up for my weekly newsletter, and never miss an episode along with other great content:Art of Healing PodcastStay in touch socially here:Healing Arts LinksLearn more about me and my offerings here:Healing Arts Health and Wellness

Emerging research shows that human egg cells resist mitochondrial aging, challenging the idea that menopause is irreversible Scientists have successfully reactivated dormant ovarian follicles in women with premature ovarian insufficiency using stem cell strategies and metabolic interventions Mitochondrial health, not egg depletion, may be the key to reversing menopause symptoms and restoring reproductive function Hormones like DHEA, T3, and progesterone, along with nutrients like vitamin A and E, are being studied for their role in rejuvenating ovaries These findings suggest menopause may be a reversible metabolic state — not a permanent shutdown

Consequences of weight loss with weight loss drugs...Enter myostatin inhibitor drugsMy latest HgbA1c is 5.9, and I'm doing everything right. What gives?I'm approaching 80. Could you discuss aging?

What are your thoughts on Alpha-ketoglutarate for healthy aging?A treatment for warts?Am I destined to develop diabetes given my strong family history of diabetes and high blood pressure?

DHEA was first identified in 1931 by Dr. Adolf Butenandt, who was awarded the Nobel Prize for Chemistry in 1939. Frequently called “the anti-aging hormone”, DHEA is a base for more than 50 hormones that are smaller or more specific carbon chain molecules in human biochemistry. As a precursor for all estrogenic and androgenic hormones, humans make DHEA naturally from birth.It's now well established that chronic stress leads to an out-pouring of cortisol and with that, a gradual depletion of DHEA. DHEA is a prohormone – a natural building block for hormones our bodies make.Over time, this hormonal imbalance can lead to brain fog, thinning bones, weight gain, low sex drive and poor Immune function.Maintaining proper DHEA levels in the body is important to your overall health and may lead to Increased energy, enhanced mood and focus, sound sleep, and better letting skin.Guest: Joining us today is Hugh Woodward, He is the President of Health2Go, Inc the makers of Twist 25 DHEA cream. Hugh is a subject matter expert on DHEA dedicating nearly 2 decades of his life studying the medical research about it, and starting a company to research, develop the safest most effective DHEA supplement that can be made and distributing it.In 2007 Mr. Woodward started Health2Go, Inc. to research and develop leading edge anti-aging and wellness products and bring them to people conveniently and cost effectively.Quality matters when supplementing with DHEA.Twist 25 DHEA Cream puts exactly what the body makes naturally – bioidentical DHEA -in the skin, where the body processes DHEA.  As a base building block for hormones, DHEA gives the body a key foundation it uses to make hormones, (especially the androgens our feel-good hormones.)Visit Twist25.com to learn more and order online. Or call 888-489-4782 that's888-489-4782. Look your best feel your best with Twist 25 DHEA creamthat's twist25.comListeners can save 15% OFF using the code: forever at checkout.Helpful Articles

Welcome back to our weekend Cabral HouseCall shows!   This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track!   Check out today's questions:    Lara: Hi, dr. Cabral! Hope you and your family are well.. I'm wondering about some ingredients in supplements, how to know which are ok? Have you maybe done a podcast about it ? It would be great to have a check list when it comes to supplements, please.. For example, gellan gum? You've said xanthan gum is not ok, guar is ok, what about the others? And I am wondering about other ingredients as well, fillers and additives.. which are ok and which are not Thank you so much! Happy healing to everyone!                                                                                                                                                      Rachel: Love your podcast thank you for all you do and hope to become an IHP one day! Anyway, this question is about my Dad. I have been doing some research, but would love your advice. He is 66 years old with diabetes and takes metformin. He has recently developed the early onset of neuropathy in his foot. What can he do to help slow the progression or even reserve the neuropathy? Supplement suggestions or diet advice? Thanks so much!                            Sarah: Hi Dr. Cabral! Will you please suggest an all natural method to get rid of flat warts I have all over my legs? I did run the big five labs and I've been working on all the imbalances for six months now, but the flat warts have not budged. Thank you so much for all you do!                                                                                                                                               Tony: Hello Dr. Cabral, Suffered some early trauma and have had chronic stress most of my life. Never ate vegetables and fruits growing up. Now, @34 I have sibo, dysbiosis, leaky gut and nervous system dysregulation. Working on them with the DESTRESS protocol,and therapy. Wondering how to introduce new foods. I'm not kidding when I say I've been on a restricted diet my whole life and new foods cause immune flares and can tank me for a few days. I'm sure like the graduated exercise program in IHP, it's about introducing them slowly and letting the immune system adapt, but wondering if you had any tips on food expansion. Ran the big 5. Low potassium/sodium. DHEA of 3, some yeast and fungal markets elevated. Want to regulate nervous system and repair my gut over the next 12 months. Thanks!                    Kelsey: Hi Dr. Cabral! Hoping you can shed some light on this. After coming off hormonal birth control earlier this year, my cycle has been irregular and my PMS symptoms have become intense. I'm wondering how long it typically takes the endocrine system to rebalance? I'm also curious if supporting the liver or increasing certain micronutrients might help speed the process. Thank you so much!                                 Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions!    - - - Show Notes and Resources: StephenCabral.com/3613 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

‣ Book Your COMPLEMENTARY CONSULATION and CALORIE CALCULATION call:- how much & what to eat

En este video te explico qué es la DHEA y por qué juega un papel tan importante en tu salud. Hablaremos de cómo sus niveles cambian con la edad y qué impacto tiene sobre el sistema inmune, el metabolismo y el bienestar general.También te contaré cuáles son sus funciones principales, los beneficios más destacados, las dosis recomendadas y los posibles efectos secundarios para que entiendas cuándo puede ser útil y cuándo no está indicada.⚡️Mi instagram: https://www.instagram.com/dr.ahernandez/

Is caffeine actually good for you? Learn from Stephen Cherniske, author of 'Caffeine Blues' as we dive into the secrets behind coffee, DHEA, cortisol, and saffron for anxiety!New episodes of Welcome to Wellness released every Friday!Hyperlinked show notes at https://www.ashleydeeley.com/w2w/caffeine

“If you really want to be strong and you want to do strength training, you need to eat carbohydrates,” explains Ana Kausel, M.D.  Ana Kausel, M.D., a board-certified endocrinologist and women's health expert, joins us today to share how women can build metabolic strength from the inside out—through muscle, nutrition, hormones, and lifestyle. - Her experience gaining 9 lbs of muscle (~3:40) - GLP-1 dosage (~6:10) - The importance of lifestyle on GLP-1s (~6:45) - Her approach to training (~11:00) - Balancing fat & protein (~14:15) - Increasing protein intake (~17:00) - The role of carbs (~17:30) - Improving metabolic health (~19:00) - Creatine & taurine (~21:00) - Testing female hormones (~22:15) - Symptoms vs. lab work (~23:45) - HRT: Compounding vs. bioidentical (~27:40) - Her take on DHEA (~28:45) - Testosterone levels (~31:15) - Use cases of GLP-1s (~35:55) - Her nutrition philosophy (~37:20) - Are NAD supplements worth it? (~47:25) - The importance of calcium (~48:00) Referenced in the episode:  - Follow Kausel on Instagram (@dranakausel)  - Check out her YouTube (https://www.youtube.com/@DraAnaKausel)  - Work with her (https://anzarahealth.com/)  This podcast was made in partnership with Gaia Herbs. Your path to stress support starts now.* Visit gaiaherbs.com and use promo code MBGPod to get 20% off. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.We hope you enjoy this episode, and feel free to watch the full video on YouTube! Whether it's an article or podcast, we want to know what we can do to help here at mindbodygreen. Let us know at: podcast@mindbodygreen.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

What are your thoughts on the benefits of magnesium threonate?Is creatine helpful in building bone strength in osteoporosis?What are your thoughts on the REMS ultrasound to diagnose bone mineral density status?What should I do about my PSA, which appears to be trending upward?  Are my diabetes meds causing erectile dysfunction?Does maltodextrin spike blood glucose tremendously?

Antioxidants and resistance training for treatment of sarcopeniaAnabolic resistance with advancing ageAre there any holistic medicine approaches to treating Lewy Body Syndrome?Is canned fish like sardines safe to eat?

Dr. Kelly Casperson is back to dig into the world of hormones, hormone replacement therapy, and how to make informed decisions for optimal health. Dr. Casperson, a board-certified urologist and women's sexual health specialist, discusses common misconceptions about menopause, the importance of timing in hormone therapy, and the benefits of vaginal estrogen and DHEA. They also touch on cardiovascular health, skin health, and the challenges of aging well in today's world. If you're a woman interested in understanding how hormones impact your overall well-being, this episode is a must-watch! As Dr. Casperson aptly puts it, 'I want you to make a decision based on facts, not fear.'Episode Overview:(0:00) Intro/Teaser(4:00) Educating on Menopause and Hormones(12:00) Estrogen and Cardiovascular Health(16:00) Redefining Menopause and Hormone Therapy(23:00) Navigating Hormone Therapy Conversations With Providers(32:00) Hormones, Skin, and Longevity(39:00) The Fallacy of Naturalistic Health(48:00) Menopause, Hormones, and Genital Health(51:00) Hormones and Female Sexual Health(1:03:00) Informed Consent and Women's Health(1:08:00) BONUS: After-Party with Dr. StephanieResources mentioned in this episode can be found at https://drstephanieestima.com/podcasts/ep441We are grateful to our sponsors:BON CHARGE - Achieve glowing skin, gain more energy, and uplevel your recovery practice with a suite of red light products. Get 15% off at https://boncharge.com/better with code BETTER.PIQUE - Designed to deeply hydrate, enhance skin elasticity & firmness and support sustained energy—exactly what we need during this stage of life. Start your daily ritual today with 20% off for life—plus a free gift to elevate your routine. Head to https://piquelife.com/drestima.LVLUP - Ultimate GI Repair combines powerful gut-healing peptides with gut-nourishing naturals to soothe your changing digestion. Go to https://lvluphealth.com/DRSTEPHANIE and use code DRSTEPHANIE for 15% off.BIOPTIMIZERS - Your digestion can take a hit in midlife, but you don't have to suffer. Learn how enzymes can help at https://bioptimizers.com/better and use code BETTER to get 10% off your order.ONESKIN - Use the power of peptides for firmer, glowing skin. Save 15% at https://oneskin.co/better with code BETTER. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Thank you for joining us for our 2nd Cabral HouseCall of the weekend!   I'm looking forward to sharing with you some of our community's questions that have come in over the past few weeks…   Lynette: I have Celiac Disease and worry about cross-contamination when eating at restaurants or friends' homes. People have suggested taking a gluten digestive enzyme, but I don't want to digest gluten. Is there anything I can take prior to eating that would rid my body of gluten, should I unknowingly come into contact with it? I'm a "silent celiac" so don't experience immediate GI upset, but instead suffer joint pain, headaches, and skin issues afterward. Living gluten-free out in the world is tough, so any suggestions to make things easier and safer are appreciated. Thanks!                                          Anonymous: I received a complimentary bottle of CBD Gummies -- thanks! Are there any contraindications with taking them? I'm thinking about them for my older parents, who are on the typical American old-age pharmaceuticals, including high blood pressure medication, statins, and Gabapentin. Will the gummies help with general aches and pains? Thank you.                                                                                                                                                                                            Sarah: I did labs through Equilife and found that my testosterone and DHEA were significantly low. For reference, I am a 49 year-old perimenopausal female. I started using about 8 mg of DHEA orally daily. (at that point I had 25 mg capsules I was splitting) Within three days of starting I had some longer lasting cystic acne on my face starting to appear. I gave it a few weeks to resolve and then began 25 mg of 7 keto DHEA daily and have had no acne breakouts at all. On my call with my IHP through Equilife to follow up from the labs, I was told that 7 keto DHEA is the same as regular DHEA and is likely just a marketing tool. Can you tell me why I reacted significantly different to the 7 keto DHEA? Several companies, some quite reputable sell it, do you recommend it in my case?                                              Anonymous: Hello, I appreciate the work you do, and would like your input to help me make a purchasing decision. I wanted to buy some Japanese selvedge jeans and notice they contain 2% Polyurethane. I had difficulty establishing whether the use of Polyurethane in clothing is harmful and wanted to know if you could direct me to resources which could provide me with more insight on this topic? Please let me know.                                                                                               Anonymous: I struggle with brain fog and low energy in the afternoons, even though I get enough sleep. Could this be related to blood sugar balance, and if so, what are some easy ways to stabilize it throughout the day?               Thank you for tuning into this weekend's Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right! - - - Show Notes and Resources: StephenCabral.com/3558 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

I am thrilled to reconnect with my dear friend, Dr. Stephanie Estima, today. In this episode, we dive into questions from listeners once more, exploring topics that range from navigating the challenges of perimenopause and parenting to shifting perspectives on fasting, nutrition, and changes in hunger and thirst cues, especially during perimenopause and menopause. We also examine how dairy may become an inflammatory food item in midlife, the benefits of hormesis, hormone therapy, and so much more. Our conversation today is honest and warm, so it is like sitting down with two close friends. Both Stephanie and I look forward to sharing many more of these Q&A sessions with you in the future. IN THIS EPISODE, YOU WILL LEARN: Some advice for mothers navigating perimenopause  How to adjust your fasting in midlife What perimenopause and menopause mean for satiety and hydration signals, and how to adapt Why some women find dairy problematic in midlife, and how to experiment with reducing it How hormesis builds resilience, and how stressors, like exercise, fasting, and cold/heat exposure, can improve metabolic and overall health What you need to consider with hormones like DHEA and pregnenolone How women with MTHFR can support methylation and detox pathways The benefits of combining strength training, Zone 2 cardio, and occasional HIIT for fitness in midlife Why you should embrace your callouses as badges of honor instead of trying to remove them The value of micro-dosing with peptides and GLP-1s Connect with Cynthia Thurlow   Follow on X Instagram LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Dr. Stephanie Estima On Instagram On her weekly podcast, Better! With Dr. Stephanie

Your sister's new deadbeat boyfriend belongs to a 1%er "outlaw" motorcycle club, which you find 100% concerning. Welcome to Feedback Friday!And in case you didn't already know it, Jordan Harbinger (@JordanHarbinger) and Gabriel Mizrahi (@GabeMizrahi) banter and take your comments and questions for Feedback Friday right here every week! If you want us to answer your question, register your feedback, or tell your story on one of our upcoming weekly Feedback Friday episodes, drop us a line at friday@jordanharbinger.com. Now let's dive in!Full show notes and resources can be found here: jordanharbinger.com/1207On This Week's Feedback Friday:Your 48-year-old sister is dating a guy from an outlaw motorcycle club where members aren't "allowed" to leave. She pays for everything while he lives with his parents, and there's been violence and federal charges against other chapters. Is your 100% concern about her relationship with this 1%er warranted? [Thanks to former FBI agent and guest Scott Payne for helping us with this one!]Your 24-year-old stepdaughter returned home after an abusive relationship, but she's lying, hoarding, possibly using substances, and creating total chaos. She vanished in the night after you tried to have an honest conversation. How do you reach someone who refuses to let you in? [Thanks to clinical psychologist Dr. Erin Margolis for helping us with this one!]You moved your family to a small Canadian island community where everyone knows everyone. Now your landlady has convinced half the town that your wife is trying to steal her partner — and it's affecting your kids. Is it time to abandon this island paradise?Recommendation of the Week: Getting regular bloodwork and checking levels on hormones, DHEA, etc.Your ex-wife fraudulently obtained over $300,000 in COVID relief funds, used the money to move away and gain custody of your son, but the FBI won't prosecute despite clear evidence. Do you keep fighting for justice or focus on rebuilding your life with what you have left?Have any questions, comments, or stories you'd like to share with us? Drop us a line at friday@jordanharbinger.com!Connect with Jordan on Twitter at @JordanHarbinger and Instagram at @jordanharbinger.Connect with Gabriel on Twitter at @GabeMizrahi and Instagram @gabrielmizrahi.Like this show? Please leave us a review here — even one sentence helps! Consider leaving your Twitter handle so we can thank you personally!And if you're still game to support us, please leave a review here — even one sentence helps! Sign up for Six-Minute Networking — our free networking and relationship development mini course — at jordanharbinger.com/course!Subscribe to our once-a-week Wee Bit Wiser newsletter today and start filling your Wednesdays with wisdom!Do you even Reddit, bro? Join us at r/JordanHarbinger!This Episode Is Brought To You By Our Fine Sponsors:DeleteMe: 20% off: joindeleteme.com/jordan, code JORDANBetterHelp: 10% off first month: betterhelp.com/jordanGrammarly: Get 20% off premium at grammarly.com/jordanHomes.com: Find your home: homes.comLand Rover Defender: landroverusa.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.