Podcasts about Insulin

Most of us think of inflammation when an ankle swells or a cut turns red. It's our body's immune system, and without it, we couldn't fight infections or repair injuries.  But when it stays switched on, this chronic inflammation can drain your energy, can affect your health over the years, and even lead to heart disease. Eventually, 1 in 3 of us will develop an inflammatory disease. In today's episode, Professor Luke O'Neill - one of the world's top 1% immunologists - explains why that matters and what you can do about it. He explores how everyday foods can push inflammation up, or help calm it. He also explains why balance matters more than banning foods like sugar, red meat, gluten, and dairy. As for your gut, you'll learn how anti-inflammatory foods like plants, fibre, and a healthy microbiome can help keep inflammation down.  By the end of the episode, you'll know how to eat, rest, and enjoy life in ways that can keep inflammation in check.  Could the way you eat help your body's healer do its job without going into overdrive? 

Find out how 31 million Americans developed high blood pressure overnight. Discover the best blood pressure tips, common high blood pressure causes, and how to lower blood pressure naturally in this comprehensive guide to everything you need to know about high blood pressure. 

What labs should women actually be asking for, and what do those numbers really tell you about your health? In this episode of Healthy As A Mother, Dr. Leah Gordon breaks down the key labs she believes women should understand, from blood sugar and fasting insulin to thyroid, iron, inflammation, reproductive hormones, vitamin D and more. She explains what these markers can reveal about metabolic health, fertility, energy, hormones, symptoms and overall health, and why looking at a single lab without the right context can sometimes miss the bigger picture.The conversation also dives into reproductive hormone testing, including estradiol, progesterone, FSH, LH, AMH, testosterone, SHBG and DHEA, with a major emphasis on understanding where you are in your menstrual cycle when certain labs are drawn. Leah and Morgan discuss why cycle tracking and understanding ovulation can give women important context about their own health, whether they are trying to conceive, trying to avoid pregnancy, navigating postpartum or breastfeeding, or approaching perimenopause.They also cover thyroid markers, ferritin and iron studies, hs-CRP and inflammation, cortisol, vitamin D, ANA, and the importance of considering a partner's semen analysis when trying to conceive. The episode ultimately comes back to one central idea: learning the basics of your own health can help you ask better questions, recognize when something deserves further investigation, and become more informed about what is happening in your body.00:00 Trailer + Introduction03:26 Understanding Women's Health Labs04:58 Why Testing Matters for Women's Health09:29 Blood Sugar, Insulin & Metabolic Health16:34 Thyroid Labs: TSH, T3, T4 & Antibodies23:18 Iron & Ferritin: What Women Should Know29:10 Inflammation & hs-CRP33:59 Why Preconception Lab Testing Matters38:57 Reproductive Hormones & Cycle Timing40:52 Estradiol: When to Test Estrogen42:17 Progesterone: When to Test It45:37 Cycle Tracking & Knowing When You Ovulate49:46 FSH & LH: What They Tell You54:42 AMH & Ovarian Reserve57:54 Testosterone, SHBG & DHEA61:14 Cortisol, Vitamin D & Stress62:38 ANA, Fertility & Partner Testing63:56 Understanding Your Labs & Advocating for Your HealthResources From This Episode:Dr. Leah's Free Fertility Lab Guide - https://drleahgordon.com/fertility-lab-guide-freebieDr. Leah's Free Fertility Masterclass - https://fertilitymasterclass.drleahgordon.com/Dr. Leah's Taking Back Fertility Program - https://takebackfertility.drleahgordon.com/Dr. Leah's Womanhood Wellness Membership - https://drleahgordon.com/joinHealthy As A Mother Podcast | YouTubeHealthy As A Mother Podcast | InstagramHealthy As A Mother Podcast | TikTokHealthy As A Mother Podcast | Merch StoreFind more from Dr. Leah:Dr. Leah Gordon | InstagramDr. Leah Gordon | WebsiteWomanhood Wellness | WebsiteFind more from Dr. Morgan:Dr. Morgan MacDermott | InstagramDr. Morgan MacDermott | WebsiteUse code HEALTHYMOTHER and save 10% at EarthleyUse code HEALTHYMOTHER and save 15% at RedmondFor 20% off your first order at Needed, use code HEALTHYMOTHERSave $260 at Lumebox, use code HEALTHYASAMOTHERUse code HAAM and save 10% at Fond

Like all animals, horses need energy to survive. That energy comes from fuel, which is why many health issues focus on what horses eat—grains, hay, supplements, and treats are all fuels we can see and buy. We often ignore how well a horse's cells turn fuel into energy, since we can't see the process or buy a quick fix. We tend to focus on taking action, usually by giving something, rather than changing how we keep them. But for hundreds of thousands of years, horses have adapted to survive on very little fuel when needed. In this podcast, we talk about why horses need their cell engines—the mitochondria, or MT—to stay flexible in how they use different fuels. Today, horses often get the same type of fuel all the time, which can cause their MT to get stuck. Just like a car engine that loses power, adding more fuel or supplements won't restore full power if the engine itself isn't working right. Timestamps: 0:00 - How do hay, water, and air make a horse move? 1:28 - Insulin resistance/dysregulation is a distraction from the actual cause of EMS (Equine Metabolic Syndrome). 2:40 - The Cell has an energy budget. 3:30 - What makes a horse thrive? 5:00 - Adding food or supplements can't cause the horse to make more energy. 6:15 - First-principles thinking about energy production in horses. 6:50 - Mitochondrial flexibility. 8:23 - Fructose is unlike glucose in that it drains energy. 9:29 - Body fat is a system that buffers energy use and can also get stuck. 10:10 - Mitochondria manage energy production in several ways. 10:50 - Summary of the energy budget. 12:40 - Mitochondrial flexibility is critical for the horse's health. 14:05 - The Laws of Thermodynamics are the physics behind biology. 15:35 - How can "sugar" be required for life, but also blamed for all diseases? ******************************* #horses #veterinary #horseteeth #horsecare #equinedentistry Join us at The Horses Advocate Community page: https://community.thehorsesadvocate.com/yt Dentistry: https://theequinepractice.com/ Horsemanship Dentistry School: https://www.horsemanshipdentistryschool.com/c/information/ Facebook: https://www.facebook.com/TheHorsesAdvocate Instagram: https://www.instagram.com/horsesadvocate/ Geoff Tucker is a veterinarian and horseman who has worked with horses since 1973, earning his Doctor of Veterinary Medicine from Cornell University in 1984. Geoff went from mucking stalls as a farmhand to starting his own equine practice. He advocates for horses by educating owners through his extensive experience, emphasizing dentistry, horsemanship, nutrition, and more.

In 2016, Singapore declared a War on Diabetes. This BRAVE compilation looks at what the Singapore blueprint gets right on health and public policy, and what that stability may cost in entrepreneurial drive. Dr. Sue-Anne Toh of NOVI Health explains TOFI (thin outside, fat inside), why Asians develop diabetes at lower BMI, and how insulin resistance works. Adriel Yong of Clouted lays out the efficiency paradox: when public services work this well, fewer people grow up as problem solvers, and state ownership leaves few business families to build on. Dr. Joshua Wang of VerImmune covers why cancer is detected too late, why new therapies are tested on late-stage patients first, and how diabetes went from a death sentence to a chronic disease. Watch the full episodes: Navigating the Longevity Market | Dr. Sue-Anne Toh - E718 https://www.youtube.com/watch?v=pP0L_qhSRJA  Singapore Works Too Well To Be A Great Startup Hub? | Adriel Yong - E705 https://www.youtube.com/watch?v=eOimzcac29w  Joshua Wang: Reprogramming Cancer, Biotech's Funding Shift & Why AI Will Rewrite Biology – E628 https://www.youtube.com/watch?v=roXPyXASiRk  Watch, listen or read the full insight at https://www.bravesea.com/blog/singapore-health-policy  BRAVE is Southeast Asia's leading tech podcast, hosted by Jeremy Au. Honest conversations with the region's top founders, investors, and operators on building startups in Southeast Asia. New episodes every week. Subscribe so you never miss one. Listen & Subscribe YouTube (English), YouTube (Bahasa Indonesia), Spotify (English), Spotify (Bahasa Indonesia), Spotify (Chinese), Spotify (Vietnamese), Apple Podcasts Follow BRAVE LinkedIn, X (Twitter), Instagram, TikTok, WhatsApp Follow Jeremy Au LinkedIn, X / Twitter, Instagram, TikTok, Facebook, Threads, Twitch Resources Get transcripts, startup resources & community discussions at www.bravesea.com #Singapore #Healthcare #SoutheastAsia #PublicHealth #Diabetes #WarOnDiabetes #HealthPolicy #Longevity #Biotech #Cancer #Immunotherapy #Startups #SingaporeStartups #VentureCapital #Founders #Entrepreneurship #SEAstartups #TechPodcast #BRAVEsea 00:00 Intro 01:02 Dr. Sue-Anne Toh: Singapore's War on Diabetes 01:47 TOFI: thin outside, fat inside 03:38 Insulin resistance and the pancreas "factory" 06:43 AI, manual labor and the WALL-E future 08:28 Adriel Yong: the Efficiency Paradox 10:04 Temasek, GLCs and the missing business families 11:39 Focus or numbing? HF0 and founder distraction 14:21 Why swing for a billion? 16:12 Dr. Joshua Wang: therapeutic, not preventative 18:36 Why cancer is detected too late 21:27 From death sentence to chronic disease 22:55 Outro

Is your breakfast keeping your menopause belly?If you're over 40 and the scales won't budge even though you're doing "everything right," the problem might not be what you're eating. It might be when you start.In this episode, I explain why I believe breakfast is one of the most important meals of the day in menopause, and why skipping it could be working against you.Inside this episode, you'll discover:✨ Why menopause changes the game. Insulin resistance and cortisol team up to store abdominal fat, and how your first meal can help break that pattern.✨ The 30g + 10g breakfast formula. 30 grams of protein and 10 grams of fibre, with simple ideas for what that looks like (including exactly what I eat every day).✨ Why rhythm matters. How a pre-workout snack, a steady eating window and a strong circadian rhythm help you protect muscle, steady your energy and feel like yourself again.You'll also hear how to beat the 3pm energy crash, what to avoid first thing in the morning, and where intermittent fasting fits.This isn't about restriction or willpower. It's one small shift that can make a big difference to your energy, your cravings and your routine.

It turns out that carb cycling does NOT improve fat loss or your metabolism. But does it have other benefits?You've heard you should load carbs on lifting days and cut them on rest days, especially after 40. Where did this idea come from?I'm breaking down the one study that comes closest to testing carb cycling and what happened when a second group of researchers reanalyzed the data. You'll also hear why the insulin and fat storage argument doesn't hold up, what one study found about insulin sensitivity after menopause, and the number of hard sets that determines whether carbs before training do anything for you. Where carb cycling comes from and why it spread beyond bodybuilding The Campbell 2020 refeed study (and later reanalysis)Why insulin and “storage hormone” arguments do not predict fat loss under matched calories What leptin and metabolic flexibility claims get (partially) rightWhat research suggests about menopause, insulin sensitivity, and body fat as the driverHow to set weekly calories, daily protein, and fiber before worrying about carb timingWhen pre-workout carbs matter most, and fed vs. fasted trainingWhy underfueling and low-carb patterns can backfire for recovery and your relationship with food If you want to stop earning your carbs and put them where your week needs them, hit play.Ask me a question for the podcast!Get the free Refeeds and Diet Breaks Guide, so you know when a structured high day is worth running and when it just makes your week harder, built for adults over 40 who lift:https://witsandweights.com/freeTimestamps:0:00 - 4 carb questions from the community 3:14 - Where carb cycling came from 7:22 - The refeed study and later reanalysis 11:59 - Insulin, storage, and a metabolic ward 13:16 - Leptin and fat-burning arguments 15:52 - Can a structured high-carb day be worth it? 17:37 - Does insulin sensitivity drop at menopause? 20:31 - Carb cycling in your actual week 22:42 - Complex carbs on lifting days 24:32 - Eating before and after you lift 27:07 - Bonus: hard sets and carbs before trainingEpisode Resources:Send me your question and get a direct reply, plus a shout-out on the show if you want oneTry Fitness Lab, my AI coaching app, with 20% off exclusive to podcast listeners

Managing type 2 diabetes can change over time, but having the right information for your patients can make those changes feel a lot more manageable. CGM can help your patients see what's happening with their blood sugar and guide what comes next.In this episode of the TCOYD Podcast, Dr. Steve Edelman and Dr. Jeremy Pettus discuss how continuous glucose monitoring is changing the way type 2 diabetes is managed for your patients, especially as treatment needs evolve over time. They explain why type 2 diabetes can progress from lifestyle changes and oral medications to GLP-1 therapies and insulin, and why needing insulin isn't a personal failure. They also explore how seeing glucose data in real time can help your patients better understand how meals, exercise, medications, and insulin affect their glucose throughout the day. The conversation gets practical with how CGM can help guide your patients' transition to basal insulin, make insulin adjustments easier and safer, and identify when mealtime insulin may be needed. Dr. Edelman and Dr. Pettus explain what overnight glucose patterns can tell you about your patients' basal insulin dose, how to recognize post-meal spikes, and why starting mealtime insulin doesn't necessarily mean adding injections at every meal for your patients. They also discuss newer basal insulins, avoiding too much basal insulin, and how automated insulin delivery systems may fit into the future of type 2 diabetes management. Ultimately, CGM gives your patients living with type 2 diabetes more than glucose numbers. It provides feedback that can help them recognize patterns, see how their treatment is working, and work with their healthcare team to make more informed adjustments as their diabetes management needs change.Key Topics:Why type 2 diabetes treatment needs can change over timeHow insulin resistance and declining insulin production affect glucose managementWhy needing insulin is not a personal failureHow CGM use is expanding in type 2 diabetesUsing CGM with lifestyle changes, oral medications, GLP-1 therapies, and insulinWhat time in range, GMI, and glucose variability can tell youHow CGM can help determine when basal insulin may be neededUsing overnight glucose patterns to adjust basal insulinWhy insulin titration matters more than the initial starting doseHow CGM can make insulin adjustments easier and saferWhen mealtime insulin may be neededWhy mealtime insulin doesn't always have to be taken with every mealHow to recognize and avoid too much basal insulinThe benefits of newer long-acting basal insulinsWhen patients with type 2 diabetes may want to consider an insulin pump or automated insulin delivery systemHow real-time glucose feedback can help people take a more active role in their diabetes management✨ Subscribe for practical diabetes management tips, technology updates, and treatment breakthroughs that help people with diabetes live healthier, more flexible lives.More diabetes resources:Website: tcoyd.orgBlog: tcoyd.org/blogPodcast: tcoydthepodcast.transistor.fmInstagram:   / tcoydFacebook:   / tcoydStay connected! Sign up for our monthly newsletter here!Support TCOYD's educational programs: tcoyd.org/donate ★ Support this podcast ★

Send us Fan MailWhat should you be doing in your 20s, 30s and 40s if you want a healthy brain at 80?This week, we're joined by registered dietitian and cognitive health expert Barbie Boules to talk about what we actually know about protecting our brains as we age and why brain health deserves our attention long before we start worrying about dementia.Barbie has been a registered dietitian for over 25 years, and her work has become increasingly focused on women's health, healthy aging and cognitive health. After her mom was diagnosed with Alzheimer's disease, the conversation around dementia prevention and protecting cognitive function also became deeply personal for her.We talk about the connection between cardiovascular health and brain health, including cholesterol, ApoB, Lp(a), blood pressure, insulin resistance and body composition, and why many of the things we do to protect our hearts may also matter for our brains.We also get into brain fog and normal forgetfulness, social media and our shrinking attention spans, multitasking, AI and whether outsourcing our thinking could have consequences for cognitive health.Then, of course, we talk nutrition: the MIND diet, berries, leafy greens, whole grains, fatty fish, coffee, alcohol, creatine and supplements. Plus, Barbie breaks down what we actually know about menopause and cognition, including the viral claim that your brain starts to “eat itself” when estrogen declines.In this episode, we cover:• How early brain health and cognitive decline should be on our radar• Normal forgetfulness vs. changes worth paying attention to• Modifiable risk factors for dementia and cognitive decline• The connection between cholesterol, metabolic health and brain health• Whether social media, multitasking and AI are changing how we use our brains• The MIND diet and what to eat for long-term brain health• Coffee, alcohol, creatine and supplements for cognitive health• Menopause, estrogen and the female brain• Cognitive reserve and why protecting your brain involves more than doing Sudoku• The realistic habits you can start now to support a healthier brain laterIf you've ever wondered how to keep your brain healthy as you age, whether brain fog is something to worry about, or what actually matters for reducing your risk of cognitive decline, this episode is for you.More about Barbie? Her websiteHer SubstackHer Instagram SHOP OUR MERCH HERE

On this episode of Vitality Radio, Jared welcomes Ellie Anderson, founder of Elevated Integrative Wellness, for a deeper look at metabolic health and why metabolism is about far more than calories and weight loss. Ellie explains how chronic stress and nervous system dysregulation can influence blood sugar, inflammation, digestion, hormone communication, sleep, and the way the body stores energy. You'll learn why the body's response to stress may actually be protective, even when the symptoms are frustrating. Jared and Ellie also discuss the importance of shifting into “rest and digest,” protecting mealtime, prioritizing quality sleep, creating margin in your day, and learning to listen differently to the signals your body is sending. The goal isn't to fight your body, but to create an environment that supports metabolic resilience and overall vitality.Additional Information:Elevated | Conversations About Health & HealingFacebook: https://www.facebook.com/elevatedintegrativewellness Instagram: https://www.instagram.com/elevated_ellie/ 378: Emotional Vitality: Using Curiosity to Take Back Control of Your Subconscious MindVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.This podcast is produced by DrTalks.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drtalks.com/channel-growth

Sleep, Growth Hormone, and Autophagy: How Rest, Diet, and Fasting Support Metabolic Health and Longevity: Nutritionist Leyla Muedin discusses how deep, early non-REM sleep boosts growth hormone for muscle, bone, fat burning, and metabolic health, and reviews a Cell study in which UC Berkeley researchers mapped hypothalamic circuits and feedback through the locus coeruleus showing a tight balance between sleep, growth hormone release, and wakefulness, with implications for metabolic disease and neurodegeneration. She connects poor sleep to higher blood sugar, insulin, and cortisol, which can suppress growth hormone, and advises avoiding sweet post-workout foods (e.g., smoothies, bananas, fruit yogurt) that stimulate insulin and blunt growth hormone, recommending protein and fat instead. She then explains autophagy and mitophagy as cellular cleanup processes linked to longevity, noting autophagy peaks after 12 hours of fasting, highlighting roles in mitochondrial quality control, immunity, and neurodegenerative disease, and mentions interventions such as fasting, exercise, ketogenic diets, and investigational inducers like rapamycin and urolithin A.

My thyroid labs are "normal," but my hair's falling out, and I'm exhausted. Is this menopause or my thyroid?If that sounds familiar, you're in good company. Andrea Donsky, nutritionist and bestselling author of Nourishing Menopause, has had Hashimoto's for more than 20 years, and once she hit menopause, her thyroid symptoms changed completely. The cold hands and weight gain she'd learned to watch for were replaced by a hoarse voice, fast weight loss, and depression.So she sat down with Dr. Jade Guerra, a chiropractor and family nurse practitioner who has spent decades in functional medicine. They talk about what Hashimoto's actually is, why so many doctors don't check thyroid antibodies, and the kinds of testing Dr. Jade uses to look for what's behind your symptoms. Then they get into blood sugar: why insulin resistance gets more common in menopause, which fruits spike you (watermelon did it to Andrea), and why a continuous glucose monitor (CGM) can tell you more than any food list.And if you've ever walked out of an appointment feeling brushed off, Dr. Jade's closing message is for you.WHAT YOU'LL LEARN- Why your thyroid symptoms can look different in menopause- What Hashimoto's is and why a thyroid antibody test is worth asking about- How mold and other toxins can sneak into everyday food- Why insulin resistance gets more common after menopause- Which fruits are easier on your blood sugar, and how to get a CGM without a prescription in the USCHAPTERS4:04 Why Doctors Don't Test Thyroid Antibodies7:27 Meet Dr. Jade Guerra + Andrea's Hashimoto's Story After Menopause9:45 Normal Thyroid Labs? Testing That Looks for the Root Cause12:52 What Is Hashimoto's? 3 Things Every Woman Should Know14:42 Plastics, Air and Water: Lowering Your Toxic Load16:32 Mold in Your Food, Mold Testing and Why Daily Poops Matter19:48 Insulin Resistance in Menopause: Why Is It Happening?23:11 Eating for Steady Blood Sugar: Fruit, Watermelon and CGMs26:25 Hair Loss, TSH and Being Dismissed by Your Doctor29:35 It's Not Your Fault: Finding a Provider Who ListensMENTIONED IN THIS EPISODEDr. Jade Guerra on Instagram: https://www.instagram.com/drjadeguerra/Fiberus (U.S. only): https://wearemorphus.com/products/fiberusEp #192, Thyropause & Hashimoto's with Dr. Amie Hornaman: https://www.buzzsprout.com/1374700/episodes/19178901-ep-192-thyropause-hashimoto-s-with-dr-amie-hornamanEp #207, Insulin, GLP-1s & Menopause with Dr. Sarah Wilson, ND: https://www.buzzsprout.com/1374700/episodes/19818368-ep-207-insulin-glp-1s-menopause-dr-sarah-wilson-ndNothing in this episode is medical advice. Talk to your own provider before starting or stopping any medication or supplement.#thyroid #menopause #hashimotosSend us Fan Mail ======Morphus: Menopause Reimagined

What is normal insulin? Learn what fasting insulin levels can reveal about insulin resistance, how to lower fasting insulin, how to decode A1C levels, and what you can learn to help prevent type 2 diabetes.

In this episode, Dr. David Jockers breaks down the hormonal loop behind stubborn belly fat that almost nobody is talking about: the cortisol-insulin death spiral. Visceral fat isn't passive storage, it's a hormone factory with two to three times more cortisol receptor sites than other fat, and the more of it you carry, the more cortisol it pulls in and the more insulin resistant it becomes.   You will learn exactly how the loop runs, from a stress response to a liver glucose dump to an insulin spike that shuts fat burning off, and why this keeps happening even when you eat clean, stay low carb, or fast. Dr. Jockers also explains how modern living flips your cortisol rhythm backward, so cortisol runs low in the morning and surges at 9:00 PM, midnight, and 3:00 AM, wrecking melatonin, deep sleep, and overnight fat burning.   From there he walks through the four cortisol traps he sees most often and a seven-step fix, including the bedtime snack that stops 3:00 AM wake-ups, why walking beats jogging for fat loss, how to swap chronic cardio for sprint bursts that raise growth hormone by 450%, and the protein target that makes fasting work instead of backfire. He closes with listener questions on testing cortisol properly, spotting visceral fat without a scan, timing your morning coffee, and why thin people can still be dangerously fat on the inside. In This Episode:  00:00 Testing Cortisol Right 00:14 Podcast Intro And Coaching 03:38 Visceral Fat Hormone Factory 04:57 Cortisol Insulin Death Spiral 07:15 Cortisol Rhythm Gone Wrong 08:53 Four Cortisol Traps 13:16 Fix Step 1 No Late Eating 14:12 Fix Step 2 Stop 3AM Wakeups 17:44 Fix Steps 3 To 7 Lifestyle 23:56 Q And A Cortisol Visceral Fat 27:41 Final Takeaways And Outro   Glutathione is your body's master antioxidant, protecting your cells from oxidative stress and supporting your natural detoxification pathways, but not all glutathione supplements are absorbed the same way. Purality Health's glutathione is a spray you simply mist onto your tongue instead of swallowing another capsule, formulated with their advanced delivery technology and extra vitamin C, and it tastes surprisingly good. Visit masterantioxidant.com/drj for a buy one, get one free special backed by a 180-day money back guarantee.   Optimizing your mineral levels is one of the most overlooked aspects of wellness, and Beam Minerals makes it a one-minute habit. The Advanced Set pairs Electrolyte and Micro Boost, made with naturally occurring plant-based humic and fulvic mineral complexes in a liquid your body absorbs easily, with no refrigeration needed, they taste like water, and they won't break your fast. Head to beamminerals.com/drjockers and use code DRJOCKERS for 20% off your first order.   "One 20-second all-out sprint has been shown to raise growth hormone by 450% for hours afterwards." ~ Dr. Jockers     Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio     Resources: Visit masterantioxidant.com/drj to get a buy one, get one free special on Purality Health glutathione, backed by a 180-day money back guarantee Visit beamminerals.com/drjockers and use code DRJOCKERS to get 20% off your first order Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/   If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/ 

Ryan, Dana, and Chris Trenkmann discuss Florida Attorney General James Uthmeier suing insulin makers and a pharmacy benefit manager over high prices.See omnystudio.com/listener for privacy information.

On this episode of Diabetes Dialogue, Diana Isaacs, PharmD, and Natalie Bellini, DNP, FNP-BC, talk through the latest addition to the weekly basal insulin landscape and what it means for clinicians starting or switching patients. Their conversation centers on real-world considerations for bringing a new insulin option into practice.Watch the video and get the full description: https://www.hcplive.com/view/diabetes-dialogue-weekly-insulin-efsitora-alfa-gets-fda-approval-for-type-2-diabetes #Diabetes #Endocrinology #DiabetesDialogue

SPONSORS: 1) AMENTARA: Head to www.amentara.com/go/JULIAN & use code JDP22 for 22% off your FIRST order. JOIN PATREON FOR EARLY UNCENSORED EPISODE RELEASES: https://www.patreon.com/JulianDorey CLIPPERS DISCORD: https://discord.gg/8QmWEKJ3BT NEWSLETTER: https://juliandoreypodcast.beehiiv.com/get-julians-top-10-books (***TIMESTAMPS in Description Below) ~ Dr. Abud Bakri, MD is a board-certified Internal Medicine physician, health educator, and medical consultant specializing in metabolic health, longevity, and clinical peptide therapies. He gained mainstream recognition as a leading expert on the biochemistry, safety, and regulation of experimental and therapeutic peptides. ABUD'S LINKS: - WEBSITE: https://abudbakri.com/ - IG: https://www.instagram.com/abud_bakri/?hl=en - X: https://x.com/AbudBakri FOLLOW JULIAN DOREY IG: https://www.instagram.com/julianddorey/ X: https://x.com/juliandorey JULIAN YT CHANNELS - SUBSCRIBE to Julian Dorey Clips YT: https://www.youtube.com/@juliandoreyclips - SUBSCRIBE to Julian Dorey Daily YT: https://www.youtube.com/@JulianDoreyDaily - SUBSCRIBE to Best of JDP: https://www.youtube.com/@bestofJDP ****TIMESTAMPS**** 0:00 - Dr. Abud, Gaza & "Medicine Lost Its Soul" 10:29 - Twelve Minutes: How Little Doctors See You 20:20 - COVID, the Thymus & Weakened Immunity 30:10 - Zinc, T Cells & Blue Zones Debunked 41:35 - Why mRNA Trust Broke Down 51:00 - Peptides Explained, Insulin in 1922 1:01:22 - GLP-1's Origin: Lizard Venom 1:10:15 - Pharma's New Target: Healthy People 1:20:00 - Sunlight, Melanoma & Cancer as Immune Escape 1:32:00 - BPC-157 and the Growth Hormone Debate 1:44:40 - Pill Mills & the Peptide Community 1:47:57 - GLP-1s, Dopamine & AI Horror Stories 1:59:30 - Why We Should Love the Sun 2:07:49 - Russian Peptides & Vladimir Khavinson's Death 2:20:14 - Epitalon & Soviet Research Lost 2:32:15 - Circadian Rhythm & Vegas Casino Design 2:42:47 - Black Market Peptides & Research Grade 3:00:22 - Where Medicine Goes in Ten Years 3:03:07 - Abud's Work CREDITS: - Host, Editor & Producer: Julian Dorey - COO, Producer & Editor: Alessi Allaman - https://www.youtube.com/@UCyLKzv5fKxGmVQg3cMJJzyQ - In-Studio Producer: Joey Deef Julian Dorey Podcast Episode 479 - Abud Bakri Music by Artlist.io Learn more about your ad choices. Visit podcastchoices.com/adchoices

This episode of Rest, Eat, Move explores why no single health marker—whether Apo B, LDL, insulin, calcium score, cortisol, or another lab value—should be viewed in isolation. The conversation argues for looking at trends and the “big picture,” combining blood work with foundational measures such as resting heart rate, blood pressure, breathing, sleep, nutrition, movement, and how you actually feel. Matt and Chris emphasize shifting from simply reacting to abnormal numbers toward understanding what may be driving them and focusing on sustainable behaviors that support long-term health.#HealthAndWellness #HeartHealth #Cholesterol #ApoB #HealthyLivingontargetliving.com

Send us Fan MailEric Moyal, founder of Project Insulin, joins Bill Bartholomew to explain how his nonprofit is working to create and sell generic insulin directly to patients at cost. The conversation covers the insulin affordability crisis, why Rhode Island can be a powerful place for early-stage startup growth, and what it takes to build a long-term biotech project in a tough fundraising environment.00:00 - Introduction to Eric Moyal and Project Insulin00:08 - How Project Insulin plans to sell insulin at cost00:42 - The real cost of insulin for patients without insurance01:11 - Why a few for-profit manufacturers control the market02:10 - Learning the issue through a partner with type 1 diabetes03:06 - The statistic that pushed him to get involved03:36 - Why this is a nonprofit and fundraising challenge, not just a science problem04:27 - Rhode Island's push into health and sciences05:26 - Why Rhode Island was a strong place for early-stage growth06:23 - Social Enterprise Greenhouse and the accelerator experience07:41 - Why Rhode Island works best as an early-stage startup ecosystem08:45 - Why building major pharmaceutical infrastructure in-state is difficult09:11 - Rhode Island's interpersonal network as its “secret sauce”10:33 - The idea of Rhode Island as a pass-through for talent and growth11:51 - Why not every business needs to become a billion-dollar unicorn13:34 - Why raising money for a long-horizon nonprofit is difficult14:54 - Project Insulin's current fundraising target and development phase15:46 - Long-term plans for national and global insulin distribution Support the showFollow Bill on Instagram and YouTube

A ketogenic diet can dramatically improve metabolic health while sending LDL-C through the roof. So what's actually happening? Dr. Josh Wageman and Dr. Laura Buchanan break down their new study, "Increased LDL-C reduction with ezetimibe in ketogenic diet-induced hypercholesterolemia." The results raise some fascinating questions. In 14 patients who developed very high LDL-C while following a ketogenic diet, ezetimibe cut median LDL-C from 254 to 127 mg/dL—a remarkable 53% reduction. Why was the response so much greater than what's typically seen with ezetimibe? Could altered cholesterol absorption help explain why some people experience dramatic LDL increases on keto? Josh Wageman, Matt Calkins, and Laura Buchanan take us inside the study, explore the biology behind the findings, discuss what the results can—and cannot—tell us about cardiovascular risk, and explain why much more research is needed. If you've ever wondered why LDL can rise so dramatically on a ketogenic diet—and what might be driving it—this is a conversation you won't want to miss. In this episode, Dr. Tro, Dr. Buchanan, Dr. Calkins, and Dr. Wageman talk about… (00:00) Intro (05:07) Statins, lipids, and ezetimibe (08:44) Insulin resistance, the liver, and the ketogenic diet (15:01) The results from Drs. Josh, Laura, Tro, and Matt's cohort study (see links below) (24:24) Some side effects and other downsides of statins (25:47) Statins and lipid lowering (32:26) Plaque reduction (41:45) Recent studies on statin use and effectiveness in reduction of all-cause mortality (43:50) Why it is such a massive task to begin changing long-held medical paradigms (54:43) Rapping about lipids (57:38) Outro For more information, please see the links below. Thank you for listening! Links: Please consider supporting us on Patreon: https://www.lowcarbmd.com/ Resources Mentioned in this Episode: Increased LDL-C reduction with ezetimibe in ketogenic diet-induced hypercholesterolemia (STUDY): https://www.researchgate.net/publication/413581066_Increased_LDL-C_reduction_with_ezetimibe_in_ketogenic_diet-induced_hypercholesterolemia Josh Wageman: IG: https://www.instagram.com/wagemanjosh/ Book: https://www.amazon.com/dp/B0DTJ1HJ4Y?lv=shuf&channelId=500&plpRedirect=mhFallback Website: https://lifelovelipids.com Dr. Laura Buchanan: X: https://x.com/LauraBuchananMD The Society of Metabolic Health Practitioners: https://thesmhp.org Dr. Matt Calkins: X: https://x.com/MattCalkinsMD Dr. Brian Lenzkes:  Website: https://arizonametabolichealth.com/ Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author Dr. Tro Kalayjian:  Website: https://toward.health Twitter: https://twitter.com/DoctorTro IG: https://www.instagram.com/doctortro/ Toward Health App Join a growing community of individuals who are improving their metabolic health; together.  Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.  Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888  Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US Learn more: https://toward.health/community/

APR Health Solutions Peptides: www.aprhealthsolutions.com - code nyleOptimize HRT Clinic: https://members.optimize-hp.com - code nyleMerch: https://www.aykons.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'nyle' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘nyle' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.com00:00:00 Intro 00:01:41 Growing Up Across the Middle East00:02:40 College at ASU & Age Banter00:04:08 Soccer to Bodybuilding Transition00:05:32 First Cycle & Men's Physique Debut00:08:03 Middle East vs US Bodybuilding Culture00:10:27 The Oxygen Gym Kuwait Formula00:12:05 Vegas vs Dubai: The Bodybuilder Lifestyle00:13:46 Founding The Dungeon Gym Dubai00:16:42 Coaching Elite IFBB Pros00:17:17 Old-School Grit vs Modern Optimization00:20:39 Why New Lifters Quit Too Fast00:22:17 Social Media Pressure & Derek Lunsford00:24:09 Faith, Mindset & Diversity in Dubai00:29:13 The Hard Truth About Genetics00:32:00 Customizing Protocols for Longevity00:36:26 Troubleshooting Digestion & Biofeedback00:40:39 Post-Show: Rebound vs Health Phase00:43:10 Learning When Not to Be a Bodybuilder00:45:17 Starting an Off-Season & Waist Control00:47:03 Physiological Weight Adaptation00:48:39 The Reality of Open Bodybuilding Gear00:52:07 Finding Your Sweet Spot & Allostatic Load00:54:34 Modern Cardiovascular Health Monitoring00:56:33 Why Health Supplements Are a Scam01:01:17 Winning the Pro Card in Morocco01:02:30 The Physical Toll of Open Bodybuilding01:04:23 Prepping on 600g Carbs & Peak Week01:06:24 The 2022 Breakthrough Off-Season01:07:32 Adding GH & Insulin to Break Plateaus01:09:48 Training Evolution: Full Body to 4-Day Split01:12:16 Why Heavyweight Pros Need More Rest01:14:31 Eating 6,000 Calories in an Off-Season01:17:06 High-Dose GH Side Effects & Edema01:18:22 Sleep Apnea & Heavyweight Sleep Hacks01:22:45 Post-Show Disaster: HbA1c Spikes to 9.001:24:35 High-Dose Mealtime Insulin Protocols01:26:42 Coaching IFBB Olympians01:27:45 Case Study: 98kg Classic to 112kg Open01:31:28 The Hardest Obstacle: US Visa Denials01:34:17 Using GLP-1s to Make Weight in Classic01:35:30 The Science of Back-to-Back Show Peaking01:37:50 Hosting Patrick Tuor at The Dungeon01:39:15 Compounds to Avoid: The Case Against Boldenone01:40:49 Primobolan vs Masteron Breakdown01:44:25 Trenbolone vs Testosterone: Myth vs Reality01:45:22 Prepping on 2,000mg Sustanon with Zero AIs01:46:22 The Dubai Pro Scene01:47:29 Optimal Protein Intake per Kg01:49:17 Managing Cystatin C & Blood Pressure Spikes01:51:08 Moving from Light Heavy to Heavyweight01:56:06 Drug Protocols for the Post-Show Rebound01:57:31 Pulling Gear & GH During Peak Week01:59:09 One Message to the World: Cherish Life

On this episode of Vitality Radio, Jared takes a deep dive into gout, uric acid, and the metabolic factors that may be driving the problem. He explains how uric acid is produced, why poor clearance may matter as much as overproduction, and how insulin resistance, fructose, sugary drinks, alcohol, and dietary purines can influence uric acid balance. You'll also learn why red meat may not deserve all of the blame it gets and why liquid sugar and beer are far more important considerations. Jared also explores natural options including tart cherry, celery seed extract, quercetin, and systemic enzymes, along with practical strategies for supporting healthy uric acid levels, kidney function, a balanced inflammatory response, and overall metabolic health.Gout Support ProductsAdditional Information:#567: Systemic Enzymes in Action: How to Pair Supplements for Pain, Scar Tissue, Cysts, and Women's Health#568: Systemic Enzymes in Action: How to Pair Supplements for Autoimmune Conditions, Immune Health, Cardiovascular Support, and Athletic RecoveryVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.This podcast is produced by DrTalks.comhttps://drtalks.com/channel-growth

A condition named for the ovaries turns out to run through the muscle, the liver, and the pancreas. Insulin is the signal connecting them, and different organs hear it differently. Oluyemisi Famuyiwa, reproductive endocrinologist and founder of the Montgomery Fertility Center, returns to walk through it. This episode is based on her article "How insulin drives polyendocrine metabolic ovarian syndrome," published on KevinMD. You will hear why the pancreas makes more insulin when muscle stops responding, and why the ovary and the liver are still listening when it does. You will hear what that does to androgen levels, and why acne, chin hair, and stubborn weight show up before irregular cycles. You will hear why body weight is a poor guide to who has PCOS, since lean patients carry the same elevated androgens and irregular cycles. And you will hear which tests she orders and why she works this across internal medicine and endocrinology. Press play for the reframe she leaves clinicians with: this is more than the ovary and more than insulin. This episode is brought to you by ModMed. Welcome to your new AI-Powered Practice from ModMed. We're transforming specialty care by embedding AI Assistants across your entire workflow. Our all-in-one platform of EHR, patient engagement, practice management, and RCM helps reduce repetitive work while keeping you firmly in control. Trained on de-identified data from nearly a billion patient encounters, this isn't just smarter software. It's a new way of working for specialty medicine, more efficient and more connected to the patient experience. Start building your AI-Powered Practice at modmed.com. VISIT SPONSOR → https://www.modmed.com/ SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast

My labs came back "normal." So why do I feel like I'm falling apart and gaining weight?If you've heard that from your doctor, this one's for you. Andrea sits down with her friend (and her own doctor), Dr. Sarah Wilson, ND, founder and clinical director of Advanced Women's Health. They recorded this with no script, for both of their podcasts, and it shows. They laugh a lot, and they still get into the stuff most doctors skip.Sarah explains why she tests insulin and inflammation, not just FSH and LH, and why you can feel off for years before your labs show perimenopause. She uses a bank account analogy for insulin and fat storage that finally makes it click. Then they talk honestly about GLP-1 medications, what the big weight loss trials actually did, and why food, supplements, and medication don't have to be an either/or choice.Sarah also shares something personal. She used to weigh 100 pounds more than she does now, while eating well and working out, and it took years to find out why.WHAT YOU'LL LEARN- Why your labs can look normal when you feel anything but, and what "late reproductive" means- Which blood tests to ask about in perimenopause, including fasting insulin and inflammation markers- How insulin affects where your body stores fat, and why eating less often backfires- What the GLP-1 studies don't put in the headlines- 3 surprising things that can add to perimenopause weight gainCHAPTERS2:00 Why a Doctor Who Won't Budge Is a Red Flag2:31 Meet Dr. Sarah Wilson, ND5:36 "I Don't Know Where to Start" and How Your Feed Shapes What You Know8:06 Normal Labs but You Don't Feel Like Yourself? The Stage Before Perimenopause11:25 Blood Tests to Ask for in Perimenopause: Insulin and Inflammation15:08 How Insulin Drives Menopause Belly Fat (the Bank Account Analogy)19:46 Food First, and When You Need Extra Help24:20 GLP-1s in Menopause: What the Weight Loss Studies Don't Tell You27:47 Why Doing Everything at Once Backfires32:18 "When Did You Last Feel Like Yourself?" Weight, Confidence and Real Goals38:27 3 Surprising Causes of Perimenopause Weight Gain40:34 Menopause as Your "Done Caring" Era, and Why Laughing Helps50:56 How to Find a Doctor Who Actually ListensMENTIONED IN THIS EPISODEAdvanced Women's Health (Dr. Sarah Wilson's clinics in Ontario and BC): https://www.advancedwomenshealth.ca/Finally Lose It by Dr. Sarah Wilson, ND: https://amzn.to/4jpTM9eThe Advanced Women's Health Podcast: https://podcasts.apple.com/us/podcast/the-advanced-womens-health-podcast/id1772009349Dr. Sarah Wilson on Instagram: @drsarah_ndSarah's first visit to the show, Perimenopause Decoded: 7 Root Causes of Hot Flashes, Weight Gain & Brain Fog: https://youtu.be/u_otR4Oy-70Ep #195, GLP-1 and Muscle Loss with Natalie Bean: https://www.buzzsprout.com/1374700/episodes/19287911-ep-195-glp-1-and-muscle-loss-in-perimenopause-what-to-eat-to-protect-it-with-natalie-beanEp #203, Perimenopause Weight Gain and the 17 Reasons Why: https://www.buzzsprout.com/1374700/episodes/19670683-ep-203-perimenopause-weight-gain-and-the-17-reasons-whyThis episode is not medical advice. Talk to your own provider before starting or stopping any medication or supplement.Send us Fan Mail ======Morphus: Menopause Reimagined

In this episode, Tara answers your health questions straight from Instagram, covering everything from gastritis and SIBO to leaky gut, insulin resistance, thyroid issues, low ferritin and B12, and GLP-1 medications. She dives into why H. pylori should be properly ruled out with gastritis, why SIBO requires breath testing, the limitations of zonulin testing, and why low ferritin doesn't automatically mean iron deficiency. She also shares her thoughts on supporting insulin sensitivity through muscle, protein, fibre, stress management and lifestyle before reaching for supplements. The conversation also gets into thyroid health and Hashimoto's, the realities of aging, iron and B12 testing, and GLP-1 medications. It's a wide-ranging Q&A designed to help you look beyond symptoms and single test results and take a more thoughtful approach to your health. In this episode:  Chronic gastritis and the importance of ruling out H. pylori SIBO testing: why symptoms and stool tests aren't enough Leaky gut, intestinal permeability and the limitations of zonulin testing Insulin resistance and PCOS: supplements vs. foundational lifestyle strategies Building muscle, protein and fibre for metabolic health Thyroid health, Hashimoto's and the impact of stress and viral illness Why aging doesn't mean you have to suffer through symptoms Understanding low ferritin, iron deficiency and more comprehensive iron testing B12 testing, absorption and the gut connection GLP-1 medications, muscle preservation, digestion and side effects MENTIONED IN THIS EPISODE: EPS 130: Do not take oral / IV iron until you've listened to this.   ------------------------------------------------------------------------- You're Invited to my upcoming Gut Masterclass! Cut gluten, dairy, soy, sugar, gone low FODMAP, and paid for expensive tests, yet still having bloating and poop problems? This is the simple fix nobody has told you about!   Here's what I'll be covering:  Why chasing trigger foods keeps you stuck in a harmful elimination cycle that makes your gut worse, and the shift that changes your relationship with food Why "I've done the testing and taken the supplements" has not given you answers or relief yet, and what to do instead  The missing layer to gut healing that moves you from the test-supplement-restrict cycle to a strategy that heals your gut for good [ SAVE YOUR SPOT HERE ]  

Samuel Reich, Chief Executive Officer at SAB Bio, is developing a fully human antibody therapy designed to transform type 1 diabetes treatment by preserving patients' beta cells and their ability to produce insulin, rather than just managing symptoms with insulin and glucose monitoring. The drug is produced using the company's bovine platform which uses genetically modified cows to generate human immunoglobulins offering a safer more scalable alternative to rabbit-derived therapies. If successful, this approach could represent a functional cure, potentially transforming type 1 diabetes from a disease requiring daily insulin management to one requiring only periodic infusions. Samuel explains, "Our mission at SAB Bio is to transform what it means to get a type 1 diabetes diagnosis by changing the course of the disease, and not just treating the symptoms, with our new medicine, which is called SAB-142. Why type 1 diabetes? It's a major global unmet medical need that has largely been underserved in research until recently."  "Insulin and glucose monitoring are the standard of care, but they don't treat the disease. They don't treat the patient's illness. They just manage the symptoms and allow the patient to survive. So, they're essential, but they're not helping the patient be healthier or manage the disease process. Our mission is to treat the disease causing type 1 diabetes by saving the patient's beta cells and saving the patient's ability to make their own insulin. And exogenous insulin is no substitute for the patient's own ability to make insulin." "So we have a platform at SAB called the TcBovine, which is a transchromosomal bovine. And these are cows that are healthy and happy cows that look like normal dairy cows, but the cows make human IgG, or human antibodies, instead of cow IgG. And we vaccinate our cows with human thymocytes and purify the IgG from the cow plasma. And our drug is a fully human immunoglobulin, which targets human thymocytes. So, it does what the rabbit drug does, thymoglobulin, but it's human and can be given more safely without making the patient sick, and can be given for the life of the patient to continue to preserve their beta cells for the long term." #SABBio #Type1Diabetes #TD1 #JDRF#Immunology #ClinicalResearch #Endocrinology #AutoimmuneDisease #MedicalInnovation #BetaCells #T1D #HealthcareInnovation #ClinicalTrials sab.bio Download the transcript here

Samuel Reich, Chief Executive Officer at SAB Bio, is developing a fully human antibody therapy designed to transform type 1 diabetes treatment by preserving patients' beta cells and their ability to produce insulin, rather than just managing symptoms with insulin and glucose monitoring. The drug is produced using the company's bovine platform which uses genetically modified cows to generate human immunoglobulins offering a safer more scalable alternative to rabbit-derived therapies. If successful, this approach could represent a functional cure, potentially transforming type 1 diabetes from a disease requiring daily insulin management to one requiring only periodic infusions. Samuel explains, "Our mission at SAB Bio is to transform what it means to get a type 1 diabetes diagnosis by changing the course of the disease, and not just treating the symptoms, with our new medicine, which is called SAB-142. Why type 1 diabetes? It's a major global unmet medical need that has largely been underserved in research until recently."  "Insulin and glucose monitoring are the standard of care, but they don't treat the disease. They don't treat the patient's illness. They just manage the symptoms and allow the patient to survive. So, they're essential, but they're not helping the patient be healthier or manage the disease process. Our mission is to treat the disease causing type 1 diabetes by saving the patient's beta cells and saving the patient's ability to make their own insulin. And exogenous insulin is no substitute for the patient's own ability to make insulin." "So we have a platform at SAB called the TcBovine, which is a transchromosomal bovine. And these are cows that are healthy and happy cows that look like normal dairy cows, but the cows make human IgG, or human antibodies, instead of cow IgG. And we vaccinate our cows with human thymocytes and purify the IgG from the cow plasma. And our drug is a fully human immunoglobulin, which targets human thymocytes. So, it does what the rabbit drug does, thymoglobulin, but it's human and can be given more safely without making the patient sick, and can be given for the life of the patient to continue to preserve their beta cells for the long term." #SABBio #Type1Diabetes #TD1 #JDRF#Immunology #ClinicalResearch #Endocrinology #AutoimmuneDisease #MedicalInnovation #BetaCells #T1D #HealthcareInnovation #ClinicalTrials sab.bio  Listen to the podcast here

Performance-Einbruch auf langen Strecken oder mitten im Rennen? Wenn der „Mann mit dem Hammer“ kommt, liegt das oft nicht am falschen Training, sondern an deinem Stoffwechsel. Die Lösung heißt: Metabolische Flexibilität. In dieser Folge sprechen wir mit der Ernährungswissenschaftlerin Prof. Dr. Anja Carlsohn genau darüber: Du erfährst, wie du deinen Körper trainierst, effizient zwischen Fett- und Kohlenhydratverbrennung zu wechseln, um im Wettkampf und Alltag leistungsfähiger zu sein.(00:05:25) - Metabolische Flexibilität, was ist das?(00:09:10) - Vorteile einer guten metabolischen Flexibilität(00:13:40) - Bist du metabolisch flexibel?(00:17:45) - Messbarkeit & Diagnostik(00:28:25) - So trainierst du deinen Stoffwechsel(00:38:40) - Nüchterntraining als Stoffwechselboost?(00:47:00) - Deshalb solltest du Krafttraining machen!(00:51:55) - Welche Rolle spielt Insulin?(00:58:30) - Train-Low-Modell(01:03:30) - Low Carb & Ketogene Ernährung(01:15:30) - 3 Take-Home Messages für dich!Die findest du Anjas Kontakt über die HAW Hamburg: https://www.haw-hamburg.de/person/anja-carlsohn/Hier findest du die Arbeitsgruppe Sporternährung der DGE: https://www.dge.de/gesunde-ernaehrung/gezielte-ernaehrung/ernaehrung-und-sport/hFoto: Anja CarlsohnMusik: The Artisian Beat - Man of the Century➡️ Zalando x Berlin MarathonZalando ist auch dieses Jahr wieder Hauptsponsor des Berlin Marathons am 27.9.! Auf Zalando.de findest du ein riesiges Sortiment an Laufkleidung und Inspiration für deinen Race-Look. Vom 24.-27.09.2026 erwartet dich in Berlin am Kurfürstendamm 229 außerdem ein hammer Programm: Kostenlose Laufband-Analysen, Panel-Talks mit Pros, Community Runs, Fueling Station, und am Marathon-Sonntag eine fette Afterparty. Hier geht's zur kostenlosen Anmeldung: https://www.zalando-events.com/runzoneOder komm am Sonntag vorbei in der Zalando-CheerZone direkt vor der U-Bahn-Station Nollendorfplatz! Hosted on Acast. See acast.com/privacy for more information.

20260915 Tuesday Topics on diabetes and ACB Diabetics in Action (ACBDA) This episode of Tuesday Topics focuses on diabetes and the work of ACB Diabetics in Action (ACBDA), a Special Interest Affiliate of the American Council of the Blind. Over the past three years, ACBDA has made significant progress on issues that many once considered extremely difficult to address. Insulin pumps, the cost of insulin, and accessible ways to monitor blood sugar are just some of the many areas in which ACBDA has worked to bring about greater access and change. Larry Gassman, president of ACBDA and a member of the Tuesday Topics team, has assembled a panel to discuss where things stand today for people living with diabetes, particularly those who are blind or have low vision. Diabetes remains one of the leading causes of vision loss among working-age adults and also affects many blind and low-vision young people living with Type 1 diabetes. Our guests discuss the progress that has been made, the challenges that remain, and the work ACBDA continues to do on behalf of people with diabetes. Find out more at https://acb-tuesday-topics.pinecast.co

John Wilcox was diagnosed on his ninth birthday, noticed insulin pooling in his pod window, and turned it into a company. He talks about building Diatech Diabetes, selling it, and running marathons with type 1. twiist - A different type of insulin pump has arrived ABLEnow save for today's needs or invest for tomorrow Eversense CGM MiniMed Tandem Mobi ** Use code JUICEBOX to save 20% at Cozy Earth  CONTOUR NextGen smart meter and CONTOUR DIABETES app Dexcom G7 Go tubeless with Omnipod 5 or Omnipod DASH * Get your supplies from US MED  or call 888-721-1514 Touched By Type 1 Take the T1DExchange survey Apple Podcasts> Subscribe to the podcast today! The podcast is available on Spotify, Google Play, iHeartRadio, Radio Public, Amazon Music and all Android devices The Juicebox Podcast is a free show, but if you'd like to support the podcast directly, you can make a gift here or buy me a coffee. Thank you! *The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Omnipod 5 Controller is not waterproof.  ** t:slim X2 or Tandem Mobi w/ Control-IQ+ technology (7.9 or newer). RX ONLY. Indicated for patients with type 1 diabetes, 2 years and older. BOXED WARNING:Control-IQ+ technology should not be used by people under age 2, or who use less than 5 units of insulin/day, or who weigh less than 20 lbs. Safety info: tandemdiabetes.com/safetyinfo Disclaimer - Nothing you hear on the Juicebox Podcast or read on Arden's Day is intended as medical advice. You should always consult a physician before making changes to your health plan.  If the podcast has helped you to live better with type 1 please tell someone else how to find it!  

In this episode of Reclaim Your Rise, Lauren sits down with Kelsey Lynn Stokes and Francesca Spinello, co-founders of Calycanthus Lingerie, a company creating feminine, functional insulin pump holders for women who wear tubed pumps.Kelsey's story with Risely started years before Calycanthus existed. After living with T1D since age 13, she came to Risely at one of her lowest points with diabetes. Through 1:1 coaching, she brought her A1C from 8.1% to 6.3% and began changing her relationship with T1D.Now, she's taking an insecurity she remembers having as a 22-year-old woman starting on an insulin pump and turning it into something that gives other women more choice in how they dress, date, celebrate, and express themselves.Plus, Kelsey takes us behind the scenes of her career in film and television as a script supervisor, and how living with T1D has given her a unique perspective on diabetes representation on screen.WHAT WE COVER:How Kelsey went from an 8.1 A1C and nearly in tears asking for help to a 6.3 and building a company for the T1D communityThe heartbreaking question Kelsey asked the night before getting her first insulin pump at 22How losing a dress on a train in Italy eventually led to a patented product for women with T1DWhy Kelsey once wondered, “Who's going to love me if I have this on?” and the emotional side of wearing an insulin pump while dating and being intimateThe difference between hiding your diabetes and simply not wanting it to be the first thing people seeWhat TV gets painfully wrong about T1D, from someone who works behind the scenesWhy Kelsey says her 13-year-old self would have been “less scared” if she could see her life nowCONNECT WITH KELSEY + CALYCANTHUS:Kelsey Lynn Stokes(founder): @thewanderingdiabeticCalicanthus Lingerie: @calycanthuslingerieShop ProductsWHAT'S NEXT:

In this episode of Dismantling You, I sit down with Bracha Banayan, Family Nurse Practitioner, Founder & CEO of IVDRIPS and Hello Dose, for a conversation that reframes almost everything we are told about weight loss. Bracha argues that the number on the scale is the least interesting part of the story, and that what we should actually be chasing is metabolic health. We unpack the glucose and insulin dance happening in the body every day, why so many of us are living in a high insulin state without knowing it, and how that quietly drives the inflammation sitting underneath so many modern conditions. For anyone navigating fertility, this matters far more than it might sound. Every system in the body, from cognitive function to egg quality, works better when inflammation comes down.We also get personal. Bracha has been openly candid about her own egg freezing journey, including the rounds that did not go the way she hoped, and what she learned about the difference between fighting reality and accepting it. She shares why she believes women should be checking their AMH levels in their twenties rather than their mid thirties, and why muscle is the closest thing we have to a cheat code for longevity. We get into her upcoming book, the idea of a body set point and why willpower is not the whole story, and where she thinks women's healthcare is heading over the next decade. It is a conversation about biology, but it is really about refusing to live with regret.__________________________________________________

You haven't changed your food. You haven't changed your workouts. So why does the scale keep climbing?Dr. Tamara Beckford breaks down what's actually happening in your body during this shift, and why "eat less, move more" misses the real cause. Using a story many women will recognize, she walks through the SHIFT Method: five hormonal changes driving this weight gain, and a specific move for each one. Muscle loss. Insulin resistance. Where hormone therapy fits. What tools actually help and why.You deserve to know the rules have changed before you spend one more year blaming yourself for something your hormones are doing.Resources & Next Steps:The 5 biggest lies keeping you sharp, rested, and feeling like yourself again (live webinar, Sept 22) https://go.trulybalancedwc.com/brain-fog-exhaustion-webinarNot sure if it's hormonal? Take the free menopause quiz: https://api.leadconnectorhq.com/widget/quiz/WxaSc55oV4C7b0jwBFAP

Try TrueDark glasses: https://truedark.comTry Danger Coffee: https://dangercoffee.com/discount/davetubeTry Suppgrade Labs: https://shopsuppgradelabs.com/Try Longevity Gummies: https://www.timeline.com/partners/dave-aspreyThis video walks you through the complete biological timeline of a 36-hour sugar fast, from insulin dropping and liver glycogen draining to fat burning, ketone production, lower inflammation, and sharper mental clarity. You'll see how quickly your metabolism can start switching back to the fuel system it was built to use.Thank you to our sponsors!Butcher Box | Go to ButcherBox.com/HUMANUPGRADE to get $20 off your first box, plus your choice of free ground beef for life, or free chicken thighBrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power BundleiRestore | Unlock your best hair & skin with @iRestorelaser and HUGE savings on iRESTORE with code DAVE at irestore.com/DAVE00:00 – Sugar's Deadly Toll01:31 – Insulin's Hidden Damage02:52 – The Glycogen Reserve04:12 – Liver Fuel Runs Low05:29 – Reversing Insulin Resistance07:30 – Brain's Fuel Problem07:53 – Ketones: Backup Fuel09:24 – The Hormonal Reset10:46 – Visible Physical ChangesConnect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Upgrade Labs: https://upgradelabs.com40 Years of Zen: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Episode SummaryHbA1c turns up on almost every routine blood panel, and in this Monday mini episode Mikki looks at how much it can genuinely tell you. She starts with the physiology — haemoglobin picks up glucose non-enzymatically, red cells live 100 to 120 days, and the result is a weighted average of glucose exposure that leans heavily on the most recent month. That matters more than it first appears, because anything that shortens or lengthens red cell lifespan moves the number without blood glucose changing at all. Iron deficiency, heavy menstrual bleeding, foot strike haemolysis in runners, thalassaemia and sickle trait, recent blood donation and B12 deficiency can each push a result in one direction or the other.From there Mikki works through the research-based critiques: insulin resistance and beta cell decline can precede an abnormal HbA1c by many years, the test is highly specific but only about 50 per cent sensitive against an oral glucose tolerance test, an average conceals the shape of the glucose curve, and both genetics and ordinary measurement noise move the number independently of glucose. She closes on the practical side — where HbA1c does earn its place, why she still thinks a result of 40 or 41 deserves a conversation with your doctor, and which markers are worth reading alongside it.Key TopicsWhat HbA1c actually measures. Glycation is non-enzymatic with no regulatory brake, so it proceeds in proportion to how much glucose is around and how long the cell is exposed. A red cell cannot repair it, making it a passive record of the preceding 8 to 12 weeks.The "three-month average" is weighted, not even. About 50 per cent of the movement toward a new value happens in the first month, which is why a result can shift over six weeks.Falsely low results. Haemolysis of any cause, haemoglobinopathies such as sickle trait and thalassaemia trait, ongoing blood loss, blood donation, recent transfusion, advanced liver disease, and starting iron treatment in someone iron deficient.Falsely high results. Untreated iron deficiency anaemia, B12 and folate deficiency, splenectomy or functional asplenia, and aplastic anaemia.Athletes get it from both directions. Foot strike haemolysis lowers A1c relative to true glucose exposure, while the iron deficiency common in female athletes raises it — and the two distortions can partly cancel out, so the number alone will not tell you which is happening.Correcting iron can drop A1c without any dietary change. Mikki's worked example is a woman going from 42 to 37 mmol/mol once her iron is sorted, and her concern is that the change gets credited to a nutrition intervention she never needed.The cut-offs, in New Zealand and US units. Roughly 30 to 39 mmol/mol normal, 41 mmol/mol pre-diabetes and 50 mmol/mol diabetes locally, against WHO and ADA thresholds of 42 and 48 mmol/mol. Type 2 diabetes throughout, not type 1.HbA1c is a lagging signal. Insulin markers can diverge from controls up to 20 years before diagnosis, and beta cell function is already down around 50 per cent by the time someone meets diagnostic criteria — so a normal HbA1c is compatible with a long stretch of compensated insulin resistance.Specific but not sensitive. Against an oral glucose tolerance test, sensitivity of about 50 per cent with specificity around 97 per cent, and screening work in which the HbA1c criteria missed a large majority of pre-diabetes.What to read alongside it. Fasting glucose, ideally fasting insulin, waist-to-height ratio, triglyceride-to-HDL ratio and a fasted lipid panel — plus your own historic trend rather than the population cut-off.Chapters00:00 How HbA1c works and what distorts it03:41 Athletes, foot strike haemolysis and iron06:23 New Zealand and US cut-offs08:40 Why HbA1c lags insulin resistance12:12 Averages, genetics and measurement noise15:41 Your own trend, and ethnic differences18:41 Where HbA1c earns its place21:31 Sign-off and new recipesGuest / ResourcesSolo episode — no guest.Referenced in the episodeWorld Health Organization — pre-diabetes around 42 mmol/mol (6%), diabetes at 48 mmol/mol (6.5%)American Diabetes Association — diabetes at 48 mmol/mol (6.5%)Mikki discusses findings from a number of published studies through the episode. They are described in the audio rather than cited by name, so no reference list is given here.Tests and markers discussedHbA1c · fasting glucose · fasting insulin · oral glucose tolerance test · continuous glucose monitor · HOMA2-IR · HOMA2-B · ferritin · fasted lipid panel · triglyceride-to-HDL ratio · waist-to-height ratioFind MikkiInstagram, Threads and X — Mikki WillidenFacebook — Mikki Williden NutritionWebsite — mikkiwilliden.com — one-on-one calls and the recipe portal Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwillidenNZ listeners - save 10% off Calocurb by using the code Mikkipedia10 at www.calocurb.co.nzSave 20% on all Nuzest Products WORLDWIDE with the code MIKKI at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comCurranz supplement: MIKKI saves you 25% at www.curranz.co.nz or www.curranz.co.uk off your first order

Can you reverse cataracts naturally? It depends. Find out what causes cataracts, tips for natural cataract reversal, the connection between cataracts and blood sugar, and the best eye health tips to support your eyes long term. 

*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]*Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2 *HEALTH AUTONOMY [COURSE]*Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy*JOIN THE COMMUNITY*Join my Community [It's Free!]: https://bit.ly/PhysionicCommunity2*EMAIL LIST*1-2 Weekly Email of Value [It's Free!]: http://bit.ly/2AXIzK6*HIRE ME FOR CONSULTING:* Consulting: https://bit.ly/3dmUl2H Created with Biorender0:00 - Introduction1:09 - No Good Research on Health Effects of Fiber5:21 - This is what we Need!8:08 - Whoops.. Hypocrisy? 12:50 - Main PointsReferences [1] Park Y, Subar AF, Hollenbeck A, Schatzkin A. Dietary fiber intake and mortality in the NIH-AARP diet and health study. Arch Intern Med. 2011;171(12):1061-1068. doi:10.1001/archinternmed.2011.18[2] Chuang SC, Norat T, Murphy N, et al. Fiber intake and total and cause-specific mortality in the European Prospective Investigation into Cancer and Nutrition cohort. Am J Clin Nutr. 2012;96(1):164-174. doi:10.3945/ajcn.111.028415[3] Buil-Cosiales P, Zazpe I, Toledo E, et al. Fiber intake and all-cause mortality in the Prevención con Dieta Mediterránea (PREDIMED) study. Am J Clin Nutr. 2014;100(6):1498-1507. doi:10.3945/ajcn.114.093757[4] Li S, Flint A, Pai JK, et al. Dietary fiber intake and mortality among survivors of myocardial infarction: prospective cohort study. BMJ. 2014;348. doi:10.1136/bmj.g2659[5] Katagiri R, Goto A, Sawada N, et al. Dietary fiber intake and total and cause-specific mortality: the Japan Public Health Center-based prospective study. Am J Clin Nutr. 2020;111(5):1027-1035. doi:10.1093/ajcn/nqaa002[6] Burn J, Bishop DT, Mecklin JP, et al. Effect of aspirin or resistant starch on colorectal neoplasia in the Lynch syndrome. N Engl J Med. 2008;359(24):2567-2578. doi:10.1056/NEJMoa0801297[7] Robertson MD, Bickerton AS, Dennis AL, Vidal H, Frayn KN. Insulin-sensitizing effects of dietary resistant starch and effects on skeletal muscle and adipose tissue metabolism. Am J Clin Nutr. 2005;82(3):559-567. doi:10.1093/ajcn.82.3.559[8] Ziai SA, Larijani B, Akhoondzadeh S, et al. Psyllium decreased serum glucose and glycosylated hemoglobin significantly in diabetic outpatients. J Ethnopharmacol. 2005;102(2):202-207. doi:10.1016/j.jep.2005.06.042[9] Abutair AS, Naser IA, Hamed AT. Soluble fibers from psyllium improve glycemic response and body weight among diabetes type 2 patients (randomized control trial). Nutr J. 2016;15(1):86. doi:10.1186/s12937-016-0207-4[10] Solà R, Bruckert E, Valls RM, et al. Soluble fibre (Plantago ovata husk) reduces plasma low-density lipoprotein (LDL) cholesterol, triglycerides, insulin, oxidised LDL and systolic blood pressure in hypercholesterolaemic patients: A randomised trial. Atherosclerosis. 2010;211(2):630-637. doi:10.1016/j.atherosclerosis.2010.03.010[11] Burke V, Hodgson JM, Beilin LJ, Giangiulioi N, Rogers P, Puddey IB. Dietary protein and soluble fiber reduce ambulatory blood pressure in treated hypertensives. Hypertension. 2001;38(4):821-826. doi:10.1161/hy1001.092614[12] Wolever TM, Jenkins DJ, Mueller S, et al. Psyllium reduces blood lipids in men and women with hyperlipidemia. Am J Med Sci. 1994;307(4):269-273. doi:10.1097/00000441-199404000-00005Please use the following link to submit your critique: https://bit.ly/PhysionicCritiqueDisclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.

We are now on major podcast streaming services!! Catch NOFODcast every Tuesday night at the following links: @nofodcast itunes.apple.com/us/podcast/id1363254594 www.stitcher.com/podcast/nofodcast @nofodcast player.fm/series/nofodcast playmusic.app.goo.gl/?ibi=com.googl…o-pr-mu-pod-16 open.spotify.com/show/2chygBiLWVQDy70vDK6cbQ www.youtube.com/channel/UCvo0YoRFkPGCipJ-_6Vjiqg www.twitch.tv/nofodcast

TL;DRA few weeks ago someone asked me on Instagram: if I could only choose four tests to check whether the terrain — the internal environment — is still safe for cancer to return, which four would I pick? This episode is the answer. The four are a metabolic panel (glucose, insulin, HbA1c, triglyceride/HDL ratio, hsCRP, vitamin D, homocysteine), deuterium levels, the omega-3 index, and 8-Oxo-guanine (a marker of oxidative DNA damage). I also cover four bonus markers — LDH, NK cell activity, ferritin, and GlycoMark — and where to get several of these run yourself if your doctor won't order them.* Book a Metabolic Blueprint Session with me: calendly.com/tripleplaydoc/complimentary-consult* Order your own omega-3 index test: OmegaQuant* The core idea: the right question isn't “did it come back” — it's “is my body still a place cancer could thrive.” That's the terrain, and it's what conventional follow-up rarely checks.* Test 1 — Metabolic Terrain Panel: glucose, insulin, HbA1c, triglyceride/HDL ratio, hs-CRP, vitamin D, and homocysteine. Insulin resistance and chronic inflammation are consistently linked to cancer recurrence,¹ and “normal” lab ranges are far looser than the optimal ranges Dr. Mike targets post-cancer.* Case story: “Sandra” had a clean oncology bill of health, but her metabolic panel told a different story — every marker inside “normal,” every one outside optimal. Six months of correcting it, and she felt like herself again.* Test 2 — Deuterium levels: an overlooked marker of mitochondrial function. Excess deuterium gums up ATP production, and cancer cells' metabolism may get a competitive edge in a high-deuterium environment.³* Test 3 — Omega-3 Index: a ~3-month tissue-level reading of EPA/DHA in red blood cells — a better marker than diet recall, with direct ties to inflammation and immune surveillance.⁵ Order it yourself through OmegaQuant.* Test 4 — 8-Oxo-guanine: a direct, real-time biomarker of oxidative DNA damage — not theoretical risk.⁶* Bonus markers: LDH, NK cell activity, ferritin, and GlycoMark round out the picture when standard labs won't order the core four.* Bottom line: these aren't one-and-done tests — they're a dashboard. Ask for them by name, and track trends over 3/6/12 months.References* Obesity, metabolic syndrome, insulin resistance, and chronic inflammation as drivers of cancer risk and recurrence — Klinická onkologie: 10.48095/ccko2026S36* Vitamin D's role in immune function, anti-tumor effect, and patient prognosis — Nutrients: 10.3390/nu15112592* Blocking intracellular deuterium accumulation prevents cancer-related gene expression, tumor development, and tumor recurrence — 10.1177/10732748211068963* Deuterium-depleted water inhibits proliferation and migration of cancer cells in vitro — Biomedicine & Pharmacotherapy: 10.1016/j.biopha.2013.02.001* Omega-3 index / red blood cell EPA+DHA methodology — Journal of Clinical Lipidology: 10.1016/j.jacl.2019.07.001* OGG1 and repair of 8-oxoguanine oxidative DNA lesions, linking oxidative damage to cancer and inflammation — DNA Repair: 10.1016/j.dnarep.2025.103827* Natural killer cell activity and tumor immune surveillance — International Immunopharmacology: 10.1016/j.intimp.2026.117160Links mentioned:* Book a Metabolic Blueprint Session: calendly.com/tripleplaydoc/complimentary-consult* Order an omega-3 index test: OmegaQuantDisclaimer: This article is educational, not medical advice. Please talk to your doctor or a qualified functional medicine practitioner before ordering or acting on any of the labs discussed below, especially if you're currently in treatment, pregnant, nursing, or managing another chronic condition. Optimal ranges cited here reflect my own clinical approach and are not a replacement for guidance from your own care team. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit tripleplaydoc.substack.com/subscribe

Join us for a FREE live Q&A with Dr. Salcedo on September 10 at 9:00 AM PT / 12:00 PM ET and ask her your questions directly. Register here.What if the uterus is an end organ, responding to insulin and inflammation the same way the heart, kidneys, and liver do?Dr. Andréa Salcedo is a board-certified OBGYN (DO, MPH, FACOG) and associate professor at Loma Linda University School of Medicine whose research and clinical practice, which she calls conscious gynecology, examine gynecologic disease through a metabolic lens.In this episode she walks through the evidence that uterine fibroids share progenitor cells with atherosclerotic plaque, why she now teaches residents that fibroids are cardiovascular disease of the uterus, and how high insulin acts at the level of the brain stem to block ovulation. The conversation also covers her clinical observations on fasting insulin thresholds by body type, the renaming of PCOS to PMOS, what hormonal contraceptives do and do not treat, the role of chronic stress and adversity in gynecologic disease, and the four insulin-resistant transitions of a woman's life.Questions Answered in This Episode:Why are uterine fibroids being reframed as cardiovascular disease of the uterus?Can the menstrual cycle function as a metabolic vital sign?How does insulin, acting as a stress hormone, shut down ovulation?Is there an optimal fasting insulin for reproductive health, and does body type change the answer?What does the shift from PCOS to PMOS change for diagnosis and treatment?What happens to insulin resistance in perimenopause, and was the Women's Health Initiative misread?Viewers will come away with a physiological framework that treats heavy periods, fibroids, irregular cycles, and PCOS as early signals of metabolic dysfunction rather than isolated hormone problems.Special thanks to the sponsors of this episode:✅ Genova Connect: Get 15% off any Genova Connect test kit with code METABOLICLINK here. ✅ Cowboy Colostrum: Get 25% off your entire order with code METABOLIC here. ✅ Zocdoc: Find and instantly book a top-rated doctor here. ✅ fatty15: Get 15% off a 90-day starter kit with code METABOLICLINK here.More LinksLive Q&A with Dr. Salcedo, September 10, 9:00 AM PT (free): register hereDr. Salcedo's website: consciousgynecology.comDr. Salcedo on YouTube: @consciousgynecologistDr. Salcedo on Instagram: @consciousgynecologistPaper: The uterus is an end organ: a preliminary study of the association between abnormal uterine bleeding and hyperinsulinemia (Menopause, 2025)Paper: Therapeutic Carbohydrate Restriction as a Metabolic Modality for the Prevention and Treatment of Abnormal Uterine Bleeding (Nutrients, 2023)Dr. Salcedo is speaking on chronic stress, adversity, and gynecologic health at the Ketogenic Foundation conferenceThe Metabolic Initiative (expert lectures, CME, ad-free episodes, live Q&As; first 7 days free): membership.metabolicinitiative.comIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: InstagramFacebookYouTubeLinkedInPlease keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

This is the final week of our four-part series on the 7th-leading cause of death in the United States.  In this episode, you'll find out:—Why it is vital to get checked because so many people are unaware that they have Diabetes or Pre-Diabetes.—The symptoms of Diabetes you should be aware of.  And how Type 2 Diabetes leads to weight gain, while Type 1 Diabetes leads to weight loss. —The importance of breastfeeding to reduce a child's chance of developing Diabetes in their lifetime.  And why Dr. Prather says proper prevention includes getting both parents checked even before the baby is conceived. —Why Dr. Prather always checks for Enteroviruses as a contributor to the development of Diabetes. —How antibiotics and vaccines can cause added stressors to a child's immune system.  And why having pets can make a difference in strengthening a child's immune system. —The astonishing difference in the food supply since the 1980's in terms of the amount of chemicals now in our food.  And why Fiber is so essential for both weight loss and Diabetes.    —The "magic number" for fat percentage in men and women that causes a jump in Diabetes. —The definition of Insulin Resistance and how it can be prevented. —How Holistic Integration can help Type 1 Diabetics to reduce their need for Insulin by as much as 50%, which improves their overall health and longevity. —Why Dr. Prather says that Holistic Integration is "extremely, extremely successful" in reversing Neuropathy.http://www.TheVoiceOfHealthRadio.com*Receive exclusive bonus content as a member of our Voice Of Health Patreon Community:https://www.patreon.com/cw/VoiceofHealthPodcast

What if the cholesterol numbers you've been watching aren't telling you the whole story about your heart? In this episode, Dr. Mariza sits down with cardiothoracic surgeon Dr. Philip Ovadia to explore why he believes metabolic dysfunction and insulin resistance deserve far more attention when assessing cardiovascular risk, especially for women entering perimenopause and menopause. Dr. Ovadia shares what he's learned after 25 years in heart surgery, including why he's now routinely operating on patients in their 40s and even 30s. They break down the metabolic warning signs that can appear decades before advanced heart disease, from rising blood pressure and waist circumference to fasting insulin, glucose, triglycerides, and HDL. You'll also hear their discussion about cholesterol and advanced lipid testing, how changing hormones can affect women's cardiometabolic health, and why resistance training, real food, muscle, sleep, and blood sugar stability matter. Plus, Dr. Ovadia explains how continuous glucose monitors can provide real-time insight into your metabolic health and the heart imaging he recommends women discuss with their healthcare providers. Listen now to discover the metabolic clues your body may be giving you today and how to start protecting your heart for decades to come. DR. PHILIP OVADIA Dr. Philip Ovadia is a board-certified cardiothoracic surgeon, founder of Ovadia Heart Health Center, and author of Stay Off My Operating Table and Stay Off My Kitchen Table. After performing thousands of heart surgeries, Dr. Ovadia shifted part of his work toward prevention, helping patients identify and address metabolic dysfunction before it progresses to advanced cardiovascular disease. His virtual practice focuses on improving metabolic health as a strategy for reducing heart disease risk. IN THIS EPISODE Why Dr. Ovadia believes insulin resistance deserves more attention in heart disease prevention The five basic metabolic markers he wants women tracking Why your personal blood pressure baseline matters in midlife What fasting insulin can reveal before blood sugar becomes obviously abnormal Why cholesterol alone may not give you the complete picture of cardiovascular risk How muscle and resistance training support metabolic and heart health What a continuous glucose monitor can teach you about food, energy, and blood sugar When Dr. Ovadia recommends considering coronary artery calcium imaging QUOTES “It's never too early to start thinking about this, but it's also never too late.” “Cholesterol is not the main thing driving heart disease.” “Low-fat diets, they simply don't work.” RESOURCES MENTIONED Order my newest book: The Perimenopause Revolution http://drmariza.com/book Stop surviving and start thriving, join Midlife on Fire Collective now https://drmariza.com/trial Stay Off My Operating Table by Dr. Philip Ovadia Dr. Ovadia Website Dr. Ovadia Facebook Dr. Ovadia Instagram Dr. Ovadia Youtube RELATED EPISODES 769: Is It Perimenopause or Something Else? How to Finally Connect the Dots with Dr. Mariza 750: The Underlying Cellular Cause of Midlife Fatigue, Brain Fog & Low Motivation with Andrew Salzman 650: Unlock Your Health: The Ultimate Biomarker & Lab Blueprint to Thrive in Midlife and Beyond

In this episode, Dr. David Jockers goes solo to break down five of the most common health myths he hears on a regular basis, the ones most people you know believe and are unknowingly putting into practice against their own health. You will learn why sunshine isn't the enemy your dermatologist made it out to be, why skipping breakfast can be one of the healthiest things you do, why saturated fat and cholesterol aren't driving your heart disease risk, why a low-salt diet might be working against you, and why a high-protein diet isn't damaging your kidneys, plus the real, evidence-backed root causes behind each of these conditions. In This Episode:  00:00 Heart Health Myth Teaser 00:21 Welcome and Share Request 01:03 Reviews Email and Coaching 04:30 Myth 1 Sunshine Benefits 07:23 Myth 2 Rethink Breakfast 10:40 Myth 3 Saturated Fat Truth 14:10 Myth 4 Salt and Insulin 18:04 Myth 5 Protein and Kidneys 21:07 Wrap Up and Next Steps   Purality Health's Glutathione Spray is a simple way to support your body's master antioxidant, delivered by spray instead of another capsule or tablet, formulated with advanced delivery technology and added vitamin C. Go to masterantioxidant.com/drj for a buy-one-get-one-free offer backed by a 180-day money-back guarantee.   Navigating the endless supplement and diet noise is exhausting. Quince Daily Superfood Greens packs 78 expertly sourced vitamins, minerals, probiotics, adaptogens, and superfoods into one scoop, sweetened naturally with monk fruit so it won't spike blood sugar. Go to quince.com/drjockers for free shipping and 365-day returns.   "What actually increases your risk of heart disease are things that promote oxidative stress and inflammation — sugar, refined carbohydrates, and processed seed oils." ~ Dr. Jockers     Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio     Resources: Visit masterantioxidant.com/drj to get a buy-one-get-one-free offer on Purality Health's Glutathione Spray Visit quince.com/drjockers for free shipping and 365-day returns on Quince Daily Superfood Greens Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/   If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/ 

Stan Efferding is an icon of bodybuilding, powerlifting, and elite evidence-based coaching.Stan returns with his unique ability to interpret cutting-edge research and combine it with decades of real-world experience coaching athletes at every level.We discuss:• Whether you actually need to be in a calorie surplus to build muscle• How large a calorie surplus should be if the goal is maximizing muscle while minimizing fat gain• Whether the traditional “dirty bulk” is finally dead• Why gaining weight faster does not necessarily mean gaining muscle faster• Which populations may still benefit from more traditional bulk-and-cut cycles• How bodybuilding and fitness influencers have distorted expectations around realistic rates of muscle growth• The impact of performance-enhancing drugs on what people believe is naturally achievable• What is really happening with so-called “hardgainers”• Why increases in NEAT can make gaining weight surprisingly difficult for some people• Practical strategies for eating more when gaining weight is the goal• Whether people starting at a higher body-fat percentage should get leaner before focusing on maximizing muscle growth• Insulin resistance, body composition, and recomposition• What matters more for muscle growth: nutrition or mechanical tension?• Why training provides the signal and nutrition supports the adaptation• Why simply consuming more protein cannot compensate for inadequate training• Mechanical tension and what actually drives hypertrophy• Effort and effective rep ranges• Training volume and time efficiency• Where diminishing returns begin with additional training volume• Minimum effective volume versus maximizing muscle growth• Why more exercise does not automatically produce more weight loss• Common mistakes people make when using exercise for fat loss• The role of cardio in weight management• Why cardio calories are more complicated than simply reading the number on a machine• How to reconcile step counts, structured cardio, and energy expenditure• Why exercise needs to be enjoyable enough to sustain• And much moreFollow Stan on Instagram:@stanefferdingCHAPTERS01:47 Do You Need a Calorie Surplus to Build Muscle?05:41 Training Matters More Than the Surplus09:24 PEDs and Unrealistic Muscle-Growth Expectations14:36 Hardgainers, Appetite, and NEAT18:02 Practical Strategies to Eat More29:55 Training Beats Simply Eating More Protein31:18 Mechanical Tension Explained32:48 Effort and Effective Rep Ranges33:22 Training Volume and Time Efficiency36:35 Diminishing Returns From More Training39:21 High-Volume Training Anecdotes42:20 Minimum Effective Training Volume44:34 Exercise and Weight-Loss Mistakes52:43 Make Exercise Enjoyable53:48 Reconciling Steps and Structured Cardio55:57 Final Thoughts and Where to Find StanSUPPORT THE SHOWIf this episode helped you better understand nutrition, muscle growth, training volume, or fat loss:• Subscribe and check out more episodes• Share the episode on social media and tag @andrewcoatesfitness• Send it to someone who still thinks building muscle requires eating everything in sightFOLLOW ANDREW COATESInstagram: @andrewcoatesfitnesshttps://www.andrewcoatesfitness.comPARTNERS AND RESOURCESRP STRENGTH APPUse code COATESRP:https://www.rpstrength.com/coatesJUST BITE ME MEALSUse code ANDREWCOATESFITNESS for 10% off:https://justbitememeals.comMACROSFIRST — FREE PREMIUM TRIAL• Download MacrosFirst• Begin setting up your account• When asked, “How did you hear about us?” enter: ANDREWKNKG BAGS — 15% OFFhttps://www.knkg.com/Andrew59676VERSA GRIPPShttps://www.versagripps.com/andrewcoatesTRAINHEROIC — FREE 90-DAY TRIAL• Visit: https://www.trainheroic.com/liftfree• Reply to the email you receive or email trials@trainheroic.com• Let them know Andrew sent youL1 BIOMECHANICS AND ASSESSMENT COURSEUse code COATES:https://pro.activelifeprofessional.com/assessmentworkshopevents

Episode 26-35 My 4 Favorite Supplements For Reversing Chronic Disease Too much sugar (glucose) and/or Insulin floating around in your blood is NOT good for you. Why? Because it damages the lining of your blood vessels which then leads to a host of chronic diseases.  Or, stated another way… Most chronic diseases are caused from having too much sugar and/or Insulin in your blood. If you understand this you can understand that the key to REVERSING chronic disease is found in: 1) Reducing the amount of sugar and Insulin in the blood. 2) Healing the damage that has already occurred. On this episode I talk about whole food, natural supplements that help with this process. Give this episode a good listen if you are interested in a natural approach for preventing, and/or reversing, chronic disease. And, as always, be sure to share this episode with a friend.  Thanks!  ———————- Want to learn more? Continue the conversation regarding this episode, and all future episodes, by signing up for our daily emails. Simply visit: GetHealthyAlabama.com  Once there, download the "Symptom Survey" and you will automatically added to our email list. ———————- Also, if you haven't already, we'd appreciate it if you'd subscribe to the podcast, leave a comment and give us a rating. (Thanks!!!)  

           * This podcast is for informational and educational purposes only. It is not intended to diagnose or treat any disease. Please consult with your health care provider before making any health-related changes.

Ladies, if you have ever been told your labs look normal while your body says otherwise, this one is for you. Dr. Amy Loden is a physician who nearly died from preeclampsia and now builds her practice around what medicine misses in women. She breaks down why pregnancy complications are a warning sign, what perimenopause is really doing to you, and why heart disease deserves your attention more than you think. You will walk away knowing what to ask for and why it matters.If you have any questions about this episode or want to get some of the resources we mentioned, head over to LesleyLogan.co/podcast https://lesleylogan.co/podcast/. If you have any comments or questions about the Be It pod shoot us a message at beit@lesleylogan.co mailto:beit@lesleylogan.co. And as always, if you're enjoying the show please share it with someone who you think would enjoy it as well. It is your continued support that will help us continue to help others. Thank you so much! Never miss another show by subscribing at LesleyLogan.co/subscribe https://lesleylogan.co/podcast/#follow-subscribe-free.In this episode you will learn about:How pregnancy complications reveal health risks that were already there.Why perimenopause symptoms get dismissed as normal aging.The heart disease signs that look nothing like the classic ones.Why good quality sleep matters more than hours in bed.How to eat and move to protect your metabolic health.Episode References/Links:Vitality Medical and Wellness - https://www.vitalitymwc.orgDr. Amy's TEDx talk on pregnancy - https://beitpod.com/amytedxDr. Amy Tiffany on Instagram - https://www.instagram.com/dramytiffanyDr. Amy Loden on LinkedIn - https://www.linkedin.com/in/amy-lodenThe Postpartum Pivot by Dr. Amy Loden - https://vitalitymwc.org/read-the-bookSubmit your wins or questions - https://beitpod.com/questionsGuest Bio:Dr. Amy Loden Tiffany is a St. Louis-based physician entrepreneur, author, and TEDx speaker dedicated to women's metabolic, hormonal, and cardiovascular health. After surviving severe preeclampsia and experiencing burnout in traditional, high-volume medicine, she pivoted her career toward a personalized, root-cause approach to patient care. As the founder of Vitality, she guides women through major life transitions—from postpartum to perimenopause—to help them recognize subtle warning signs and prevent long-term illness. Through her clinical work and her book, The Postpartum Pivot, Dr. Loden empowers high-achieving women to listen to their bodies, optimize performance, and take control of their long-term health.  If you enjoyed this episode, make sure and give us a five star rating and leave us a review on iTunes, Podcast Addict, Podchaser or Castbox. https://lovethepodcast.com/BITYSIDEALS! DEALS! DEALS! DEALS! https://onlinepilatesclasses.com/memberships/perks/#equipmentCheck out all our Preferred Vendors & Special Deals from Clair Sparrow, Sensate, Lyfefuel BeeKeeper's Naturals, Sauna Space, HigherDose, AG1 and ToeSox https://onlinepilatesclasses.com/memberships/perks/#equipmentBe in the know with all the workshops at OPC https://workshops.onlinepilatesclasses.com/lp-workshop-waitlistBe It Till You See It Podcast Survey https://pod.lesleylogan.co/be-it-podcasts-surveyBe a part of Lesley's Pilates Mentorship https://lesleylogan.co/elevate/FREE Ditching Busy Webinar https://ditchingbusy.com/Resources:Watch the Be It Till You See It podcast on YouTube! https://www.youtube.com/channel/UCq08HES7xLMvVa3Fy5DR8-gLesley Logan website https://lesleylogan.co/Be It Till You See It Podcast https://lesleylogan.co/podcast/Online Pilates Classes by Lesley Logan https://onlinepilatesclasses.com/Online Pilates Classes by Lesley Logan on YouTube https://www.youtube.com/channel/UCjogqXLnfyhS5VlU4rdzlnQProfitable Pilates https://profitablepilates.com/about/Follow Us on Social Media:Instagram https://www.instagram.com/lesley.logan/The Be It Till You See It Podcast YouTube channel https://www.youtube.com/channel/UCq08HES7xLMvVa3Fy5DR8-gFacebook https://www.facebook.com/llogan.pilatesLinkedIn https://www.linkedin.com/in/lesley-logan/The OPC YouTube Channel https://www.youtube.com/@OnlinePilatesClasses Episode Transcript:Amy Loden Tiffany, MD, MBA 0:00  If we're going to call pregnancy a stress test, which is becoming an increasingly common term, is pregnancy a stress test of a woman's metabolism and her cardiovascular system? Then we have to ask, what are we stressing it for? And the way I'm looking at this is a little bit different than how I was trained, which again was if you got the problem, the solution is in the pregnancy. So what if we started looking at pregnancy from the perspective of this is an unveiling, an unveiling of what was already there, and that nothing's actually gone wrong. Lesley Logan 0:29  Welcome to the Be It Till You See It podcast where we talk about taking messy action, knowing that perfect is boring. I'm Lesley Logan, Pilates instructor and fitness business coach. I've trained thousands of people around the world and the number one thing I see stopping people from achieving anything is self-doubt. My friends, action brings clarity and it's the antidote to fear. Each week, my guest will bring bold, executable, intrinsic and targeted steps that you can use to put yourself first and Be It Till You See It. It's a practice, not a perfect. Let's get started. Lesley Logan 1:11  Oh my God, Be It babe. Get ready. Get your notepad out. Get ready. If you're driving, listen. You're gonna re-listen. You're gonna share this episode with everybody. I am so freaking stoked about the guest that we have. I fell in love with her with every single answer, and we need women like this in the medical world. So Dr. Amy Loden is our guest today. We're going to talk everything from postpartum to perimenopause and heart health, because ladies, you can't be it till you see it if you get sick, cannot. And I know it's confusing. There's so much information out there in the world, and it's like, who do we trust? What do we do? And I'm just so grateful I found her, and you're gonna love it. So make sure you get ready to hit share on this episode for women in your life and the men who need to know about what women are going through. My mind is blown on the episode. Here's Dr. Amy Loden.Lesley Logan 1:54  All right, Be It babe, I'm excited. I'm super stoked. We're gonna talk about all things women, health-related, with an amazing professional person who actually studies this stuff, not what I've read, and then I'm asserting to you because I don't want to be that influencer. I think those people need to take a little step back and let the professionals do it. We have Dr. Amy Loden here on the show, who's going to tell us everything we need to know. But Dr. Amy, we tell everyone who you are and what you rock at, kind of how you got here.Amy Loden Tiffany, MD, MBA 2:20  Sure, thanks for inviting me. I'm happy to be here, Dr. Amy Loden. I am in St. Louis, Missouri. I help primarily women over 40, but certainly anyone who's like, "How are my hormones working for my life or not? How is my weight in the mirror matching the weight in my head or not?" And all the things that come with life transitions from postpartum to perimenopause, beyond, my goal is that women who've interacted with our team will have a better care experience because it's the care experience we want each of us to have had ourselves, and because each of us are not only professionals within the medical nursing communities, we're patients too, or daughters and sisters and mothers and neighbors and all the things. We know how much it sucks to be patient, right? And so we've tried to redesign what is the best thing for our ladies. Now, in full transparency, we do have a few dudes, but most of them have had their arms twisted by our rock-star ladies, and they are the ones that are coming because they're forced to. And eventually, they decide they like us, but we're pretty cool too. So that's who we serve, and that's what we do. And happy to go into any detail or rabbit hole you want to chase?Lesley Logan 3:21  Oh my God, Amy! I love that. When people ask about the people who listen to this podcast, we have mostly women and a few good men because there are some men out there, including my husband. They want to be interested. They want to. They want their partners, the women, their lives. They want to get what's going on. They don't want them to feel like an alien or like they're alone in this journey. So I think that's really, really cool. I also just want to highlight. I love that you brought up your patients too, because as someone who I feel very lucky to go through my perimenopause journey in today's time when people actually are talking about it, versus even 10 years ago, generations were not talking about this stuff, and I just feel it's really nice because then there's information I would never have known about HRT unless my girlfriend had told me about it. Oh, that could be going on, and then I could talk to someone. Can we go back though? Yeah, I feel like to be a doctor like yourself, who has empathy and understands, like you must have gone through a journey as well. You don't just want to do this Amy Loden Tiffany, MD, MBA 4:13  Because you wanted to do this. That's true. Lesley Logan 4:16  Maybe there are a few. There might be a few, but typically, like there there has there's a story there that got you to be like I want to care about this. So can you tell us a little bit more about that?Amy Loden Tiffany, MD, MBA 4:24  Absolutely, yeah. So definitely with the traditional college to medical school road, really didn't understand that there's a and I say this with all the love in my heart, but there is a bit of brainwashing to be a good doctor, right? And what is a good doctor was who you've been told it is. It's not necessarily an external criteria. It's who does academic medical center say, and that was very different. I learned through transferring all of my non-medical student fears into the actual application of those fears, and then being a patient and living those fears. That I realized there's a whole lot we're not talking about. There's a whole lot that we're not being told, both as doctors and as women, as patients, and it's hard to realize you don't know what you don't know if you've been told you're the expert and you know everything, right? And most doctors don't go around saying they know everything, but there's enough patients who feel like that's what's communicated, that that's the language I'm using.Lesley Logan 5:18  Yeah.Amy Loden Tiffany, MD, MBA 5:19  And that's really frustrating as a patient, so I didn't realize how frustrating though it was until I was a patient, and I'm a mom of five kids, my third and fourth are twins, and really I am so grateful to live in the United States in a time in history where complicated pregnancies does not mean that mom dies, because I developed severe preeclampsia with heart failure, and my twins came 31 weeks instead of at least 37, and I nearly died the night they were born. They nearly died the night they were born, and I just am grateful that God let me be in this situation that I had the help I needed. Historically, these are not good situations. We see this on TV and in movies frequently. And something like 70,000 women a year across the globe die of the same disease I had, preeclampsia. So it's not nothing, even in our day and age, in certain countries, and even in countries where you have advanced medical care and they do everything right. It can still happen. So, that for me was the pinnacle of this isn't working. What we're telling people to do isn't working because I had done all the things.Lesley Logan 6:30  Right, you were a doctor. You did all the things. I did all the things. You enjoyed all the appointments. You were probably doing, and this is your third and fourth. So you knew what it should feel like. You knew what you should be eating. You knew all the vitamins to take.Amy Loden Tiffany, MD, MBA 6:41  Correct, and it didn't work, right? It didn't work, and so I think that is the fundamental kind of if you place a pivot on why did I change how I think about healthcare as a doctor, it was because of my experience as a patient for myself. My husband had cancer twice, so being the advocate for him in those types of things, guiding my children and now my parents through healthcare, you start to carry a lot of stories, and you start to see, wow, they're not doing what I think is just the bare minimum. And if they're not doing that for me or for my family, I know they're not doing it for everybody else.Lesley Logan 7:11  Yeah.Amy Loden Tiffany, MD, MBA 7:12  And then at the same time, holding a ton of grace in my heart because that's—they're doing what they were taught.Lesley Logan 7:17  Right?Amy Loden Tiffany, MD, MBA 7:17  Right. And they can't do differently if they don't know differently. You can't be better if you don't know to be better.Lesley Logan 7:23  Yeah.Amy Loden Tiffany, MD, MBA 7:23  So that is a really tight tension. But I thought I would just keep plodding through and just be a better doctor in that context of me being a patient until a little—I guess it was two years later. My daughter at that time, my oldest, was seven, and I had about 3000 patients. I was working somewhere between 65 and 80 hours a week, and had four kids at that time. And my daughter came up to me one night, and I'm opening the computer. I'm doing work like I do every night, and she says, "You're gonna make my birthday gifts. Like, can I help?" Right, totally innocent seven-year-old looking forward to her birthday knows that her mom shops online, right? And so she's like, "I want to pick my birthday presents," and I kind of stared at her. I was like, "No, no, I'm going to work. We'll do that later," and go watch whatever show. It's probably Paw Patrol for all I know, right? That's in the background. Go watch it. It's gonna be bedtime soon. And she just stands there, and I haven't even looked at her at this point. My eyes are on my computer. I'm just telling her this as I'm going. I'm totally not in the moment, right?Lesley Logan 8:19  Of course, because like you have so many, you have 3000 patients and four kids.Amy Loden Tiffany, MD, MBA 8:23   I can't keep up. I can't keep up. Right? I'm barely getting enough sleep. I'm not exercising, and I'm just trying to survive. And she doesn't move. And so I remember not totally slow motion, but I remember turning to her and feeling like I was going to be like, "What?" Right? What do you need? And she's just got out of the shower, so her hair's wet. She's got her pink pajamas on, bright big blue eyes, and they're full of tears. And there are just silent tears tracking down her face, and I'm horrified. Oh my gosh, what's wrong? Right now, I'm in fix-it mode.Lesley Logan 8:55  Yeah.Amy Loden Tiffany, MD, MBA 8:55  And she still doesn't really budge, and she just says in a very sad voice, "Mommy. Why do you love your job more than me?"Lesley Logan 9:05  Oh.Amy Loden Tiffany, MD, MBA 9:07  Yes. So the twins tried to kill me. She did kill me, right? Like, that was a knife in my heart because nothing ever had I wanted to be better than a so-called good doctor than to be a good mom.Lesley Logan 9:17  Yeah.Amy Loden Tiffany, MD, MBA 9:18  And that was for me the moment that I realized I'm not doing either of these well, and I'm not showing up how I want to be personally or professionally. I'm certainly not taking care of my health. I'm not doing the things I'm telling my patients to do. Like, it was a moment where I really felt the failures. I felt all the feelings, and I told my husband that night, "This is not working anymore." And he actually thought I thought was talking about our marriage, and so he was like, "Oh my gosh, what's wrong with our marriage?" Right? No, but I need to, like, redo. We have to redo this. I either have to retire, or I have to do something different.Lesley Logan 9:51  Yeah.Amy Loden Tiffany, MD, MBA 9:51  And he was like, "You're not retiring. You will drive me crazy. Go find something different to do, and I will make sure our family is okay." And so I did. And this June will be five years of having Vitality here in St. Louis and serving women and trying to lean into all the pain and the things and the feelings they're dealing with from all the things and the feelings I dealt with having walked that path.Lesley Logan 10:13  Yeah. Oh, Dr. Amy, I love that you shared that whole story because I think there's so many women who are listening here and, like, they don't have, they may have one kid or they have no kids, but, like, I think we can all relate to, like, having just too much on the plate because.Amy Loden Tiffany, MD, MBA 10:27  Right.Lesley Logan 10:28  Hello, my high-achieving woman. I see you, everyone here listening. We call recovering perfectionists and overachievers. There's nothing wrong with being a high achiever, but what happens is we tend to just keep saying yes to things, and we're like, yeah, we can fit that one more thing in, that one more thing. All of a sudden, it just comes to, like, a volcano breaking point. Yes, and because we don't, we don't see the signs early that we are at the breaking point. We don't, you know, we, it's almost, it's actually proven to be not true. But everyone uses the frog in the boiling water, right? Like, we just kind of, like, you don't realize how hot it's getting until it's until your daughter is crying in front of you. Oh, exactly.Amy Loden Tiffany, MD, MBA 11:05  Yes, it was awful. I never want to relive that moment.Lesley Logan 11:08  Yeah, but also, like, thank goodness for her because that she felt brave enough to say that. Like, what a badass she is. I mean, she's just going to be, like, she's just going to be a girl who speaks her mind. She does.Amy Loden Tiffany, MD, MBA 11:18  She's 13 now, and she heard me tell that story once, and now she's like, "Well, you have to credit me for opening your business because I hadn't said what I did." I was like, "Won't you just tone it down a notch, please?"Lesley Logan 11:27  It's called balance, babe. It's called balance. Yes. Okay. So, can we, like, let's get to some of the health stuff that I think our listeners want to—I want to definitely get into perimenopause, but I do want to, because we started with a pregnancy, and I have had family members who, you know, have had preeclampsia in their, and it's scary. So, how are pregnancy complications connected to long-term heart risk? I don't think anyone's thought about that. I just thought, like, if it's because I don't have kids, like it's going to screw up your pelvic floor, and you might have to rebuild your abs and these other things. But I didn't know it can affect your heart long term.Amy Loden Tiffany, MD, MBA 12:01  I had no idea. I'm so glad you brought that up. So I actually did a TEDx talk on this very topic, where the idea is pregnancy is so much more than just the birth of a kid. That's how we think about pregnancy in our culture. That's even how we think of it medically, right? Like if you have preeclampsia, you have gestational diabetes, you have high blood pressure, whatever in pregnancy, the answer is end the pregnancy, deliver the kid if they're old enough, right? Like, get, move it along and it's gone. But that I strongly believe is not true. We can't test this in a lab, so you have to do a little bit of extrapolation here. But if we're going to call pregnancy a stress test, which is becoming an increasingly common term, is pregnancy a stress test of a woman's metabolism and her cardiovascular system? Then we have to ask, what are we stressing it for? And the way I'm looking at this is a little bit different than how I was trained, which again was, if you got the problem, the solution is in the pregnancy. So, what if we started looking at pregnancy from the perspective of this is an unveiling, an unveiling of what was already there, and that nothing's actually gone wrong. It's scary. It's horrifying. And yes, absolutely, people die. So how can I say nothing's gone wrong? What I mean is nothing has gone wrong in the context of the situation we put your body in. It's exactly responding the way it should for the context it's in. So if I have underlying insulin resistance, and then I put a pregnancy on top of that or perimenopause, and I'm starting to have more insulin resistance. Well, of course I'm going to develop gestational diabetes. If I'm having a lot more fluid retention and I'm putting up a low weight, of course my blood pressure is going to go up, right? If I've got underlying inflammation, of course preeclampsia is going to develop. So I think we need to stop and think about it as it's not done; it is unmasked.Lesley Logan 13:42  Got it. Amy Loden Tiffany, MD, MBA 13:42  And then once you know it's unmasked, you treat it.Lesley Logan 13:45  I see. I see. Because again, we think of pregnancy as just the baby, so you have the baby, but it's well, but there's a problem, an underlying problem that the pregnancy revealed is what you're saying. And so great if having the baby is the safest thing for both people, we do that. But also, you still have this underlying issue.Amy Loden Tiffany, MD, MBA 14:01  Yes, it's still there. Correct.Lesley Logan 14:03  Yes, and I don't think anyone does that. I think they're just, "Okay. Now you don't have gestational diabetes anymore." But I have had clients who had it, and then afterwards, so what do we got? Oh, I'm fine. Are you correct? I don't think so. I'm not a doctor, but they're not fine. Don't just be diabetes. Yeah, for a moment. Yes.Amy Loden Tiffany, MD, MBA 14:19  So I actually experienced this as a patient too. I went in after my first pregnancy with gestational diabetes. At the time, I was living in New York City. I walked everywhere. I was a normal weight. I ate pretty clean, and despite being in residency, I'd got decent sleep. I didn't have any other kids. It's my first kid, so I got decent sleep. Right, but I had the baby after having had gestational diabetes. I go see my OB, and she's, "Oh, just follow up with your primary doctor." I go see my primary doctor, and he's, "Your weight's normal, your labs are normal. We're done," and that is how I was trained too. So again, lots of love in my heart. They're not; they're just not told. But for more than 10 years, we've known that women who have these high-risk pregnancies are at high risk not just for diabetes, but heart disease, stroke, kidney failure, dementia. Listen, I can't treat dementia well in the clinic, right? So why wouldn't I want all hands on deck trying to prevent it?Lesley Logan 15:07  Yeah.Amy Loden Tiffany, MD, MBA 15:07  But that's not how our medical professionals are trained—nurses, advanced practice providers, any of them. And so we're asking people and expecting people to fill in a gap they don't know exists, and so all these reproductive-age women are falling into it. And then where it gets really interesting is some of the same things you have immediately postpartum in all your different types of hormone fluctuations are matched intermittently for 10 to 15 years before menopause when you're in the perimenopausal years.Lesley Logan 15:32  What?Amy Loden Tiffany, MD, MBA 15:33  Correct, but that's why these women are feeling, "I'm going to my doctor, I'm putting on weight, I'm doing all the things, it's not working," and they're being gaslit, partly because their doctors don't know what they don't know, and partly because we're not acknowledging this is the same physiologic status of hormones that are different than baseline. So we're not in a country, and we don't have the testing that would promote or facilitate checking what is your normal hormone level at 18, so that we know what 18 should look like, and then by 45, you know, we're not. So we're trying to patchwork together a whole bunch of tests, and different labs have different testing, and different people say different things about testing. It's very confusing.Lesley Logan 16:10  Yeah.Amy Loden Tiffany, MD, MBA 16:11  And you end up with women suffering. And at the end of the day, that's the problem I'm trying to solve: is how do we stop these women from suffering? Because they are called to live big lives, to be ambitious for a purpose, for a calling. They have a lot to do, and their health is one of their biggest assets. It should not be a liability.Lesley Logan 16:27  Yeah.Amy Loden Tiffany, MD, MBA 16:27  And that's what's happening, especially for women who are trying to not work just in the home but outside the home. Right? There's a lot they're carrying. Yeah. So that's, I don't remember. Sorry, I'm having a total perimenopause moment. I don't remember where we started with that question here. I'll stop there. Lesley Logan 16:42  Don't worry, babe. I got my focus meds on the ADHD today, so I'm tracking. So we're good. But we were talking about the postpartum, and then we got into those hormones that switch as, and they can repeat into perimenopause. And I think this is fascinating. I love that you brought up. It doesn't matter if you're in the home or out of the home. We have big lives. Correct. We can't have our health be a liability, and I think for a lot of us, it feels like, like my girlfriend's a weight-loss coach for women over 40 who feel like their body gave a middle finger. That's what her coaching is, and it's all about not going to yo-yo diet. That's not going to work. We have to figure out what is the underlying issues, and it can only go so far because you said we don't test our hormones at 18. We don't do that, so we don't know what is normal for us, and I remember I was having a lot of health issues, digestive issues in my 30s, and no doctor could help me. In fact, one doctor sending me to, I was in this weird part where they study HIV and Ebola in the hospital, and she's like, "Do you know why you're here?" I don't know why I'm here. I don't. This scares the hell out of me. This feels like a department I should not be in. I'm not in any pain. I feel like I'm taking someone's spot, and so because he could, he just couldn't figure out what's going on my stomach. So I found someone who did an actual test of everything. He's so range normal. We don't know what normal is for you. We just know what the average person of this population of people that who knows who they were that were tested. So what is normal for you might not be the average. And I was, "Oh well, that's the first time anyone said anything that makes sense. That's the first time." So you can be in range, but for your hormones, but it wasn't in range for you because maybe you were used to higher testosterone, you're used to higher things. And so I love that people like you exist. I'm sorry for the frustration of your own journey, but also without people like you, women like me wouldn't have someone going, "Hey, actually, maybe you should be on testosterone right now," even though the, this is what it is. Mine was actually zero, but people, you know, we can actually get you help because I feel so much better because someone finally was listening to me and thought, "Yes, we're not going to compare you to a random person. We got to compare you to how you're used to feeling."Amy Loden Tiffany, MD, MBA 18:42  Correct. And for most people, that can't happen in the traditional system.Lesley Logan 18:47  Yeah.Amy Loden Tiffany, MD, MBA 18:47  You can't do that in a 10-minute visit.Lesley Logan 18:49  Right.Amy Loden Tiffany, MD, MBA 18:50  You can't do it when your doctor has 3000 patients, 10-minute visits, and they really don't actually know who you are.Lesley Logan 18:55  Yeah.Amy Loden Tiffany, MD, MBA 18:56  You just can't. So we've got a little bit of unrealistic expectations as a society, and then you know any women's magazine or journal article you read says, "Talk to your doctor about this." So then you go in, I'm all prepared. I have my list. I've done it too, folks. Right? This is not a criticism, but they, they can't. They don't have the ability to process it, and the way they're paid is based on the questions they ask you for insurance. So every incentive is misaligned, and at the end of the day, women, people are being screwed.Lesley Logan 19:22  Yeah, yeah. No, it's so true. So I'm glad we talked about the postpartum. I want to get into now. We're in the perimenopause, and yep, this is hard because you mentioned the hormone shift of people after postpartum is its own crazy world. I keep checking on my sister-in-law every day. How are you feeling? Are you feeling okay? Right. You feel okay? She's, "I'm fine." Are you fine? Let me just, I just want you to know. It's okay if you feel different, right? I think I'm crazy, but I know that that people don't realize how they're feeling, and it's hard to get to the doctor until it's too late. So I'm just, I'm on her. But for people like me, we didn't have children, so we have never experienced a crazy shift. We just start to experience, "I don't feel like my, anymore," and all the symptoms are so different for every single person. I'm not having hot flashes, but I'm, I got to keep my hair still here. But my inflammation was insane. I was putting on weight and working out and eating the same. And I don't understand what's going on. You know, so can we talk a little bit about what, I don't know where you want to start with that. So you tell me where you want to start with my post, my perimenopausal people who are not necessarily attributing these changes to that.Amy Loden Tiffany, MD, MBA 20:27  So I think the biggest confusion I see in the exam room conversations is that there's just question of, am I in perimenopause or not? And it's more of a less of a yes-no and more of, are you on the spectrum, and where on the spectrum are you? And so if you think of it as a sliding scale, because some months those ovaries are working really great, and you feel all the feels, and you're 18 again, but a lot of months maybe you're more like 20 or 25, right? And then maybe out of the blue, I feel like I got run over by shock. Nothing's working for two or three months, and then we're back to 25, right? And so it's ups and downs. You're like, what is happening? It is a roller coaster, and it runs anywhere from 10 to 15 years before you actually go through menopause. So I think of it as reverse adolescence, and I think it's completely ironic that God lets us have teenage girls when moms are going through perimenopause because that is just double-adolescence whammy, right?Lesley Logan 21:19  And no wonder, no wonder marriages don't survive certain things. Right, you have a daughter going through puberty and a wife with a pair of menopause. Good luck to the husband. Correct, becauseAmy Loden Tiffany, MD, MBA 21:28  I want to have sex. I don't want to have sex. I have pimples all over my face. I don't want to go to the house. I do. My belly's bloated. It's not like my mood's up. All the things, and it's all in reverse. So it's a it's a period of a woman's life that I think needs to be acknowledged, and then within the healthcare system, there's more noise about it over the last five years. You're seeing more and more people talk about this, but there's not a lot of standardization, and so you're getting chiropractic, functional medicine, traditional medicine. You're getting all sorts of different recommendations. So my hope is that over the next decade, we start to see some standardization, and we start to say this is what is normal for this population. You still have to apply it to the person. You cannot take population data and apply it to individuals and say that you're going to have good luck, bye. We'll see you in a year. That doesn't work. What I do think is that women need to know what's normal for that time, and then they need to decide, do they want to do something about it beyond what their body is experiencing? And here's some really interesting data that I hope your listeners suddenly stop and listen. If they don't hear anything I've said yet, this will be really important for women who have hot flashes and night sweats. Either one, they're actually the same thing. We call them vasomotor symptoms. When you have those at a certain degree, so that they're happening most days of the week, more than 10 times a day would be an easy target to kind of pay attention to. You have that, and you choose not to take hormones. You actually have an increased risk for cardiovascular disease and stroke. That does not mean every woman in that category can or should take it. There may be reasons they can't, but the hormones we use today are different than what in the Women's Health Initiative that came out in the early 2000s. So you're getting a lot of confusion because women are reading about data from that, not realizing that it has changed, and that study is not going to be redone. It was a huge study. We're not going to see data like that, so we have to make really informed decisions. But cardiovascular disease, hear me, ladies. Cardiovascular disease, which includes stroke and heart failure, kills more women every year than all your cancers combined. Yeah, I get the women and they come in religiously for their mammograms or their Pap tests, right? But they don't know that the bigger risk is that they're going to die of heart disease, cardiovascular stroke, and we know that one in eight women, roughly, have breast cancer risk, and those women get it. One in two women are getting heart disease. So there's one inLesley Logan 23:50  Two.Amy Loden Tiffany, MD, MBA 23:51  One in two. So that means there's two of us on this call, right? We already know I'm going to get it because I had preeclampsia. So I'm the one. Lesley Logan 23:56  I was going to say. I hope it's not maybe. I hope it's not you. But, like, thank God you know that because I think it's one and two, especially if you don't know. Because if you know that you're at risk, you do. Then you can you do something. I am. I'm double the risk for breast cancer, so I have to do an MRI and a mammogram every six months, and I have some decisions I might have to make in my life. But because I know.Amy Loden Tiffany, MD, MBA 24:18  Right, I can take.Lesley Logan 24:20  I can take action. Yeah, correct.Amy Loden Tiffany, MD, MBA 24:22  And you know, using that same kind of history, if someone comes in my office and says that I don't want to take hormones because I was a breast cancer, I'm like, that's fine. But let's look at all the facts. Let's lay it out like your financial advisor does, and then you can make an informed decision. Because just acting out of fear or reacting is not wise either.Lesley Logan 24:38  I actually really appreciate you mentioning that because it's true. If I'm, I'm very lucky in that I still get to do the HRT that I'm on, even with my risk. But also they're checking me every six months, and I'm checking me. So if anything's going to happen, we're going to catch it so much more quicker. Whereas the hard stuff, there's only so much you can do with that. And so if you're, especially if you're not aware. Say there's all conversations, but I liked the way you laid it out with the wealth manager. I just met with mine. He laid out here's where we're being aggressive. Here's where we're doing this. Here's what's going on here. We're going to move this over here because we're going to risk-manage these risks. And I think that's that's a better way to look at it because we're not going to, every single one of us is unfortunately going to experience something because it's a body. We're not a machine. Amy Loden Tiffany, MD, MBA 25:21  It wears out.Lesley Logan 25:22  I did not know it was one in two, girl.Amy Loden Tiffany, MD, MBA 25:26  Yeah, and what's even more disturbing, you may have heard a lot of women have by now that women's heart disease presents differently than men.Lesley Logan 25:32  Yeah, can you tell us just in case my people haven't heard because I didn't know it was one in two? So let's go over the signs.Amy Loden Tiffany, MD, MBA 25:38  A lot of times people think of what's the so-called traditional? It's the jaw pain, the radiation of pain from your chest up to your jaw, to your back, down your left arm. Very classic symptoms. Classic because it was studied in men, and then we have these so-called atypical for women because they're not typical compared to men, but they're classic for women. And so, got a little bit of lingo here that it doesn't make total sense. But for women, sometimes it's they just feel a lot more anxious than they've been for unclear reasons. They have this sense that something bad is on the horizon. They can't really place why their sleep is different. Maybe they're having some shortness of breath they didn't used to have. Maybe they go up the stairs in their house, with a laundry basket, and they're huffing and puffing when six months ago they weren't. So it can be very subtle differences. It could be a new fatigue. Check labs are normal, but the fatigue's still there. That worries me when I hear women say this. Unfortunately, the number one sign that you have heart disease is sudden death.Lesley Logan 26:33  Oh.Amy Loden Tiffany, MD, MBA 26:34  So let that sink in for a second. So we can't always wait on what the signs are.Lesley Logan 26:39  Yeah, we can't fix that. Right. Correct. Okay, so that's hard because our signs are also. I feel like high-achieving women would so easily brush away that anxiety.Amy Loden Tiffany, MD, MBA 26:51  All the stuff. Correct. Because I have a lot of tabs open.Lesley Logan 26:54  Yeah, I got this going on, or I haven't been working out, so of course I'm out of breath going up the stairs. They would just so easily.Amy Loden Tiffany, MD, MBA 26:58  It's May, it's graduation season. It's wedding season, right? This is just aging, and that's not the story at all. The problem is 10-minute visit with your doctor who has 3000 patients. They don't know who you are. They're not going to notice that this is different for you.Lesley Logan 27:13  Yeah.Amy Loden Tiffany, MD, MBA 27:13  Decreased exercise tolerance is a big one. And so, if you could walk three miles every day in your neighborhood, now you're like, "Wow, I'm really struggling to get through one." I'm worried about that. I want to know what's going on and why.Lesley Logan 27:25  Yeah. So I guess since one getting a 10-minute visit is hard. I, where I live in, I live in Las Vegas. Last I heard, we are short general practitioners by 1400. I don't have one. I go to a women's clinic, and I'm really grateful. It's a, it's also a student-teacher thing. So I actually, they've caught things because the students are asking the questions because they'reAmy Loden Tiffany, MD, MBA 27:44  Yes, yes.Lesley Logan 27:46  I love them. I'm so grateful for them, but are there things that women can do to check their heart, or is it just being, is it just noticing the one mile versus a three mile? What can we, what are the signs we need to be checking on?Amy Loden Tiffany, MD, MBA 27:57  Certainly be aware of what your body is telling you. Again, if you have to remember nothing else, this is another one: is that your body is smart; it will talk to you, but you have to listen.Lesley Logan 28:05  Yeah.Amy Loden Tiffany, MD, MBA 28:06  So that's really essential. If something's different, say something. You're right. There's a big collapse, if you will, of how much support we have in healthcare, whether it's nurse practitioners or chiropractor or whatever. And the issue is not all of them are trained the same way. So when I worked in the OB/GYN clinic, it became apparent to both of us, on both sides of it, that OBs know stuff about women's health. I don't know, but I know stuff about metabolic and heart health that the OBs aren't taught, and most women use their OBs as their primary care, at least to a certain age.Lesley Logan 28:32  Right.Amy Loden Tiffany, MD, MBA 28:33  And again, you don't know what you don't know, so you don't realize what you're not looking for that you should be. And our system's not set up for good collaboration. So if I could tell women, here's a checklist of things I want to make sure you get, your doctor is going to give you some resistance, most likely because they don't realize that lipoprotein with a little a, it's like in parentheses at the end of it, not the big A. Lipoprotein little a. If you have that mutation, and 10 to 20% of our population does, you have a different rate of plaque development, at least risk for that than the average risk will miss. If you have high insulin levels, you have a higher risk that you're going to be on a pathway toward diabetes. Those are not things that are standard checks. So knowing that there's other tests you can ask for, and even if your insurance doesn't cover it, they're not expensive tests. Just get it once, right? Have an idea of what's going on in your body once gives you a ton of information. I offer a lot of our patients to wear different glucose monitors, even if they're not on diabetes. And all my physicians who are listening to this are probably like, "You do what?" But the reason is, if you can figure out that your glucose and insulin are high before you develop diabetes or pre-diabetes, if you figured out that insulin-resistant stage, that's a lot easier to fix, and our doctors aren't even taught about what is insulin resistance, what is the criteria for it, and how do we reverse it?Lesley Logan 29:47  Right, because there's some prevention we can do if we have information.Amy Loden Tiffany, MD, MBA 29:50  There's a ton, and it's things women can do in their homes or their businesses. It's not stuff I'm doing in the exam room.Lesley Logan 29:56  Yeah, and that's also, you know, you're listening to this podcast, you're kind of a go. Anyway, so you're gonna, you'll take the action. Our health insurance is very bizarre. I thought it was crap because, but it has a lot of preventative stuff that goes on with it. Hey, we want to put this thing in your house and check your heart and some other levels every, I don't know, two or three times a week. They keep calling them. I have two adults. We have two ADHD adults in this household. The box is here. One of us will open it when it becomes the pressure. I just have to hang tight. We'll get there. But I'm really impressed by that because we don't have access to a regular doctor. So what information can we gather so we could be watching it and monitoring it? So we can advocate for ourselves if something comes up. So having that prevention is really amazing. Okay, so we talked a little bit about the perimenopause and the different things. What are some simple shifts that women can make now to protect their future? I mean, obviously we have a wide range of women, so the now is different. But what are some things that they could be doing? Because I do think that they are getting information from the magazines and the Instagrams, and we should get it from the person who's experienced it and has seen it. You know, so you.Amy Loden Tiffany, MD, MBA 31:00  Some easy things, and I say easy relative because they're easy to do, which means they're easy not to do. So acknowledging that, right? It's real. Number one, understanding that just because you get eight hours of sleep, if they're not high-quality hours, you've got a metabolic risk from your sleep not being normal. That's important to understand because you spend a third of your life asleep, right?Lesley Logan 31:19  What's a metabolic risk? Just in case my people. So.Amy Loden Tiffany, MD, MBA 31:22  If you don't get good-quality sleep, your cortisol goes up. It's one of your stress hormones, and when cortisol goes up, glucose goes up. When glucose goes up, insulin goes up. Insulin's your fat-storing hormone. So even without your sex hormones being involved, or the ghrelin and leptin you're hearing about with weight and GLPs and all that, just those, you're not getting good sleep. It's going to be a problem. Insulin resistance is going to go up. Insulin resistance means your cells are not listening to the insulin your body is giving it, so your body works harder to get more insulin, and the cells work harder to ignore it, and it just keeps going in a vicious cycle. So if we consider that that's the root cause of a lot of these problems we've been talking about, we fix that. Number one is get good sleep, get good-quality sleep, and it's not, not just enough time in bed.Lesley Logan 32:02  Yeah, so.Amy Loden Tiffany, MD, MBA 32:03  That's important. Number two is most people don't realize that they're doing it backwards. They're, if they're, if they're even able to get exercise in their life right now, right? So we're going to make the assumption that you figured out some exercise regimen you like. We're, we're at that level, but they're doing it at the wrong time, and they're doing it in a way that they're sabotaging their end result. So rather than going to the gym and then going and eating dinner, or going to the gym first thing in the morning and skipping breakfast and all these things, you need to eat protein and fat, and then you need to move your thighs. I don't care if that's jumping jacks, going for a walk, running up the stairs, something where your thighs are moving regularly for 10 minutes. So make it whatever you like doing. This can be the mom at home who's doing all sorts of fun class activity with her kid, right? Like moving the baby around or the teenager can be equally fun to move around for what it's worth. And then it could be the CEO who's getting ready for a meeting and has 10 minutes after eating whatever lunch she had in the five-minute break she did, right? So looking at what makes sense in your life, but 10 minutes of physical activity, ideally after every meal, that's not realistic, but that's ideal. And then you start with the one meal a day you can do, and you do it most days of the week to start with, because most of us have to figure out how to make it a habit.Lesley Logan 33:15  Yeah.Amy Loden Tiffany, MD, MBA 33:15  But movement for 10 minutes after eating, it's, it's crucial. I cannot stress that enough.Lesley Logan 33:20  I didn't realize it was. It makes total sense moving your body after eating because I like to go for a walk after I have lunch. Otherwise, I'm tired. Correct. I can't go back to work now. Amy Loden Tiffany, MD, MBA 33:30  The reason you're tired though is because your glucose goes up and your insulin went up to match it. When you walk right after you eat, glucose still goes up, but it's less, and so you have less insulin spike. Insulin is the bright driver here, and so you've got to do the movement after. And if it helps to understand why, think back to what our ancestors did 1000 years ago. Right? We weren't checking hormones. We weren't checking insulin. We weren't talking about hacks. We were trying to survive most of the time. Yeah. But the things they did is they, if they, what, after they ate, they moved around. Right? Like they were building their shelters. They were taking care of the kids. They were moving in the community, helping build, create, relocate, whatever. They were always moving, and they did not get the whole three square meals a day. That's bogus. You don't need three meals a day, okay? And most of my ladies don't realize that they're eating their nutrients potentially in the wrong order for their body. That they're eating them in the wrong time for the cycle of the month they're in, they're not getting enough protein, not getting enough fat for their hormones and their brain, and it doesn't happen quickly, right? It's months, years, maybe even a couple decades before they're, I don't know what happened, but my body in the mirror is not the body in my head. This is not who I am. There's a disconnect, and they finally are at that place where they have to do something, where the body is forcing them to stop because they've pushed it as hot as you know.Lesley Logan 34:44  Oh my God, that's a whole episode. We're having you back. I'm just telling you right now because I want to have a whole episode on the whole. Because what I do know is if you eat certain things, if you work out too late, if you get your cortisol up, sleep that. I have been trying to figure out sleep for over a decade, and I, I get good-quality sleep most of the time. But I'm obsessed with it because I'm like, I don't want Alzheimer's. I do not want heart problems. It doesn't really matter what I'm doing at the gym if I'm not sleeping. None of that matters. Doesn't matter what you're, If you don't get good sleep, all the rest is gonna just fall apart anyways. So it's interesting. It makes sense about the food because I remember when I was having problems with my cycle and I had my one of my doctor friends, she said you should try seed cycling because I just, the worst cramps and, like, the worst everything was just the worst in the world, and so I tried seed cycling and my goodness, you know, I'm not a woo-woo girl, but the seed cycling makes, I got, I had no more zits, my boobs didn't hurt as bad, everything leveled out, and I didn't need any extra hormones for it. I was, whoa, so now there must be more. We need to know about it. So we'll have to have you back for that. I can talk to you forever. So we'll just, this is part one of many. I'm just going to take a brief break and then find out if people can find you, follow you, and work with you. All right, Dr. Amy Loden, where do you hang out? You mentioned St. Louis. Can people work with you if they're not in St. Louis? How does this work?Amy Loden Tiffany, MD, MBA 36:03  Yes, absolutely. Best way to get into contact with our office is just going to our website, www.vitalitymwc.org. They can sign up for a consultation, and we can go through what their options are. There is also lots of opportunity if you don't want to work with us directly, but you want to continue the conversation and hear what we're seeing. I do all the social media I can so that people can hear what's being said in their exam rooms and have it in their real lives too. So you can do that on follow me at Dr. Amy Tiffany, whether it's on Instagram or TikTok or Facebook. You find it where they're also on LinkedIn at Dr. Amy Loden. So lots of places depends on what their needs are. One special offer I do have for your audience: we talked about pregnancy and perimenopausal bit through this conversation, they can contact my office for a free physical copy of my book, The Postpartum Pivot. And before you stop listening, ladies, and you think, "Well, I'm not postpartum." If you've had a baby, you're postpartum even it's 20 years ago. Your body's different than it was before that baby, and so you can understand what does this look like for perimenopause and other types of areas that we go through as we grow less young, but grow more wise.Lesley Logan 37:03  Oh my God! Every one of my female females, that's where your Christmas present is. Sorry, just gonna get a doctor because they don't. It's, if their doctor doesn't tell them, they don't know, right? And then they are just going through it. And I feel so bad because every woman in my life is such a badass, and then they get their body doesn't keep up with what they're wanting to do in life, and then it just becomes not just like a liability, but like this hangup. So you are amazing. Okay, you've given us some great stuff already. I mean, we're gonna have to rewind, and I'll listen to this. I've got, you know, getting my notepad out, but our bold, executable, intrinsic, or targeted steps people can take to be it till they see it. What do you have for us?Amy Loden Tiffany, MD, MBA 37:37  I want each one. When you be it as you see it, I want you to be true to what your body's telling you, and recognize nothing's gone wrong. Listen when things are happening and they seem like it's a crisis. Nothing's gone wrong. Your body's talking to you. Listen, and when you listen, you become more wise. You become a better version of yourself.Lesley Logan 37:55  Okay, I really love that. We talked about that earlier, but it's true. Some of us think our body is against us, and it's doing something to us. But really, it's like, hello. The alarm bells. Amy Loden Tiffany, MD, MBA 38:05  It's doing exactly what it should do for the situation we've put it in. That doesn't mean we like it. You get diabetes. No one's like, oh yeah, my body did exactly what it's supposed to do. But if we understand that, then it becomes a neutral thought. It's not bad or wrong. It's I didn't listen, so now I'm going to stop, and the best place to reverse is as soon as you realize you're going in the direction. Right? It's not to keep going in the wrong direction. So nothing has gone wrong. We just need to listen. We need to turn around, create a better story.Lesley Logan 38:33  Love it. Love it. This is and then so enlightening. This is so fun. Thank you so much for being you and your and and the journey that you've been on is something we can all benefit from. So thank you for that, you guys. We all need to share this episode with all the women in our lives, and I would love for you to make sure that Dr. Amy knows your favorite takeaways. Send them to the Be It Pod as well. And since I'm going to have her back, not that I even like asked her beforehand, but I'm just going to tell her she's doing that. You can send your questions, and we'll make sure we get that. So, beitpod.com/questions. Until next time, my loves, Be It Till You See It. Lesley Logan 39:03  That's all I got for this episode of the Be It Till You See It Podcast. One thing that would help both myself and future listeners is for you to rate the show and leave a review and follow or subscribe for free wherever you listen to your podcast. Also, make sure to introduce yourself over at the Be It Pod on Instagram. I would love to know more about you. Share this episode with whoever you think needs to hear it. Help us and others Be It Till You See It. Have an awesome day. Be It Till You See It is a production of The Bloom Podcast Network. If you want to leave us a message or a question that we might read on another episode, you can text us at +1-310-905-5534 or send a DM on Instagram @BeItPod.Brad Crowell 39:45  It's written, filmed, and recorded by your host, Lesley Logan, and me, Brad Crowell.Lesley Logan 39:50  It is transcribed, produced and edited by the epic team at Disenyo.co.Brad Crowell 39:54  Our theme music is by Ali at Apex Production Music and our branding by designer and artist, Gianfranco Cioffi.Lesley Logan 40:02  Special thanks to Melissa Solomon for creating our visuals.Brad Crowell 40:05  Also to Angelina Herico for adding all of our content to our website. And finally to Meridith Root for keeping us all on point and on time.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

You cannot open your phone anymore without hearing about Ozempic, Wegovy, Mounjaro, Zepbound, retatrutide, and before-and-after transformations. One person says GLP-1s are the greatest thing ever. Another says they are going to destroy your health. As usual, the truth is somewhere in the middle. In this episode, I break down GLP-1s specifically through the lens of perimenopause and menopause, because midlife women are dealing with a completely different metabolic landscape. Estrogen is changing. Muscle is easier to lose. Insulin sensitivity may be shifting. Sleep is falling apart. Belly fat is showing up where it never used to. And simply telling a woman to eat less and exercise more is not a strategy. We talk about where GLP-1s can be incredibly useful, why HRT and GLP-1s are not interchangeable, and why protecting muscle has to be one of your top priorities if you are using these medications. I also get into dosing, microdosing, appetite suppression, thyroid and hormone optimization, realistic weight-loss rates, and why the goal should never be to get as skinny as possible as fast as possible. The goal is to lose fat while preserving muscle, supporting hormones, improving metabolic health, and having an actual plan for what happens after the weight comes off. In this episode, we cover: Why menopause changes fat distribution and increases abdominal fat for many women How declining estrogen, muscle loss, sleep, and insulin resistance affect midlife weight How GLP-1 medications work beyond simple appetite suppression Why GLP-1s are not "cheating" Why GLP-1 therapy does not replace HRT Whether HRT and GLP-1s can be used together Why muscle loss is one of the biggest concerns with GLP-1 use Why protein and resistance training matter so much Why having no appetite does not mean your dose is perfect Microdosing versus standard GLP-1 dosing Why increasing your dose too quickly can backfire What a realistic rate of weight loss can look like The importance of thyroid and hormone optimization when weight loss stalls Why maintenance needs to be part of the plan from day one Who This Episode Is For This episode is for women in perimenopause and menopause who are considering a GLP-1, already taking one, or wondering whether these medications could help with stubborn midlife weight gain. It is especially for women who want to lose fat without sacrificing muscle, energy, hormones, bone health, or long-term metabolic health. If you are confused by the microdosing hype, worried about muscle loss, unsure whether you should do HRT or a GLP-1 first, or wondering why your weight loss has stalled even though you are taking medication, this episode is for you.     Sponsors BEAM: Use coupon code HORMONE for 20% off your order Try the power of copper peptides on your skin today and get 20% off your order with coupon code km20 here.     Are you in perimenopause or postmenopause and struggling with symptoms—but not getting the support you deserve? At Midlife Solutions, we specialize in hormone optimization for women in midlife. Our all-female clinical team offers telehealth care across all 50 U.S. states, with the ability to prescribe bioidentical estrogen, progesterone, testosterone, and thyroid medication.   Book your FREE Hormone Discovery Call Find out what's really driving your symptoms and what your next best steps are.   Visit the website: https://karenmartel.com   Shop the Midlife Solutions Store Over-the-counter bioidentical hormone creams and oils — no prescription needed. Including: • Progesterone • Estrogen Face Cream • Vaginal Moisturizer and more!   Take the Hormone Quiz Discover hidden hormone imbalances that could be driving your symptoms. Get personalized results (and yes, they may surprise you).   Women's Peptide Weight Loss Program Clinically guided, hormone-aware weight loss for midlife women.   Midlife RESET HRT Program A complete, supportive approach to hormone replacement therapy in midlife.   Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert   Karen's Facebook Karen's Instagram

Can insulin have a place in a fat loss diet? Scott McNally, Skip Hill and Andrew Berry talk about insulin use while dieting, whether bioidentical hormones can limit bodybuilding progress, PED use in natural shows, Anavar vs. Anadrol pre-workout, cardio vs. daily step count, knowing when body fat is too high, and the coaches who influenced them most. Support the podcast! Check out our advertisers and research partners at: http://www.thinkbigbodybuilding.com 0:00 Insulin During a Fat Loss Diet 0:30 Support the Podcast 1:20 Do Bioidentical Hormones Limit Your Progress? 9:00 PED Use in Natural Bodybuilding Shows 14:40 Should You Use Insulin While Dieting? 26:00 Anavar vs. Anadrol Pre-Workout 30:30 Pre-Workout Rituals & Getting Ready to Train 36:30 Do You Need Cardio With a High Daily Step Count? 40:00 Cheap Chicken at Costco 44:30 How Do You Know When Body Fat Is Too High? 49:45 Who Taught Us the Most About Coaching? 58:45 Listener Physique Critique 1:05:00 Skip's Word of the Day 1:08:45 Behind the Scenes

Learn how to lower blood sugar fast with simple strategies for natural blood sugar control. Discover how to support healthy blood sugar levels naturally and improve overall metabolic health.

In this Huberman Lab Essentials episode, my guest is Dr. Sara Gottfried, M.D., a Harvard-trained, board-certified gynecologist and expert in female hormone health. We discuss the key biomarkers women should track at each stage of life and how cortisol, thyroid hormone, estrogen, progesterone, and testosterone shape energy, mood, metabolism, and long-term disease risk. We also discuss PCOS, the risks and benefits of oral contraceptives, and the shift in brain metabolism that begins in perimenopause. Dr. Gottfried explains actionable tools for hormone and micronutrient testing, nutrition, stress management, and cardiometabolic screening that women can use at any age. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/huberman Eight Sleep: https://eightsleep.com/huberman Timestamps (00:00:00) Female Hormone Health (00:00:24) Family History, Intergenerational Trauma; Endometriosis, Fibroids, PCOS (00:01:31) Biomarkers by Decade; Teens & Cortisol; 20s & Sex Hormones (00:03:35) Tool: Hormone Test Timing; Micronutrient Testing, Magnesium (00:05:41) Sponsor: LMNT (00:07:17) Tool: Smoothies, Greens Powders & Microbiome (00:08:12) Nutrient Panels, Antioxidants, B Vitamins, Glutathione (00:09:34) Constipation, Thyroid Dysfunction; Trauma & Female Physiology (00:11:50) Tools: Reduce Perceived Stress, Meditation, Yoga, Breathwork (00:13:30) Opportunities by Decade; Androgens & Testosterone Decline (00:14:50) PCOS, Diagnostic Criteria, Hirsutism, Cardiometabolic Risk (00:17:10) Insulin & Glucose; Tool: Continuous Glucose Monitors (00:18:05) Democratizing Health Data (00:18:52) Sponsor: AG1 (00:20:07) Longevity "Don'ts"; Chronic Cardio & Cortisol; Tool: Adaptive Exercise (00:22:46) Oral Contraceptives, Benefits & Ovarian Cancer Risk (00:24:27) Ovarian Cancer Symptoms, Bloating, CA-125 (00:25:51) Oral Contraceptive Risks, Progestins, Inflammation; SHBG & Testosterone (00:29:08) Clitoral Shrinkage; Tools: Alternatives for Painful Periods (00:30:14) Sponsor: Eight Sleep (00:31:32) Menopause & Perimenopause; 30s Hormonal Baseline (00:33:07) Female Brain, Cerebral Hypometabolism & Alzheimer's Risk (00:35:02) Slow Brain Energy, Hormone Therapy; Hot Flashes as Biomarkers (00:36:54) Tool: Coronary Artery Calcium Score Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices