Podcasts about national research council nrc

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Best podcasts about national research council nrc

Latest podcast episodes about national research council nrc

Analytically Speaking
Ep. 36: A Day in the Life of a NIST Scientist

Analytically Speaking

Play Episode Listen Later May 14, 2025 49:43


In this episode, podcast co-hosts Dr. Dwight Stoll and Dr. James Grinias talk with Dr. Alix Rodowa, Research Chemist within the Organic Chemical Metrology Group at the National Institute of Standards & Technology (NIST) in Gaithersburg, Maryland. At NIST, she is the Environmental Sector Task Lead for the Organic Analysis Working Group for the Consultative Committee for Amount of Substance: Metrology in Chemistry and Biology (or CCQM). After discussing some of the events that sparked Dr. Rodowa's interest in science, and analytical chemistry in particular, we discuss her path to a career as a NIST scientist, including cold-emailing potential research advisors, and an experience as a National Research Council (NRC) postdoctoral fellow. We then discuss her work on polyfluoroalkyl substances (PFAS), including the development of the PFAS Interference List - affectionately known as the “PIL” - and the development of a Standard Reference Material (SRM) for that research area. We also touch on emerging uses of machine learning in workflows for analytical target and suspect screening. Finally, Alix provides some insight into a day in the life of a NIST scientist, why she enjoys working in a government laboratory, and how aspiring scientists can explore this environment as a potential career option.

SoundStage! Audiophile Podcast
Axiom Audio's New Performance44 Speakers

SoundStage! Audiophile Podcast

Play Episode Listen Later Jan 3, 2025 33:11


Axiom is a Canadian loudspeaker brand founded by Ian Colquhoun in 1980. It was one of the first companies to adopt the design principles based on the research Dr. Floyd Toole was conducting at Canada's National Research Council (NRC). Today, Colquhoun not only owns Axiom Audio, but also Bryston and Magnum Dynalab. This week, host Jorden Guth is joined by Ian Colquhoun to discuss the value engineering that made the company's new Performance44 loudspeaker line possible.  Sources: “Axiom Audio's Ian Colquhoun and NRC” on the SoundStage! Audiophile Podcast: https://www.soundstage.life/e/axiom-audio-s-ian-colquhoun-and-nrc-origin-dr-floyd-toole-music-types-twin-tweeters-measurements/ “Axiom Audio's M100 v4 Loudspeaker”: https://www.youtube.com/watch?v=7cdPUHJKx70 “Canadian Hi-Fi Trilogy: Axiom Audio, Bryston, and Magnum Dynalab—All Under One Expanding Roof” by Doug Schneider: https://www.soundstagehifi.com/index.php/opinion/1785-canadian-hi-fi-trilogy-axiom-audio-bryston-and-magnum-dynalab-all-under-one-expanding-roof Chapters: 00:00:00 Announcement 00:00:30 What makes Performance44 different? 00:15:00 Music Break: “My Bet” by RocknStock 00:16:12 Why now? 00:30:41 Outro: “Batteries Are for Flashlights, Not for Pickups” by Art Against Agony

Agripod
Rural municipalities AND Root rot in pulse crops

Agripod

Play Episode Listen Later Aug 22, 2024 23:21


It's a new chapter for Ray Orb, as he is now adjusting to life after being the president of the Saskatchewan Association of Rural Municipalities (SARM) for the last ten years, and twenty overall with the Board. Orb talks about what he has seen in his two decades with the organization, working with different levels of government, the key issues, accomplishments and regrets.Root rot in pulse crops has grown to be a devastating issue for growers across Western Canada, so a team of University of Saskatchewan (USask) researchers and colleagues at Agriculture and Agri-Food Canada (AAFC) and the National Research Council(NRC) led by Dr. Sabine Banniza (PhD) of USask's Crop Development Centre (CDC) is searching for ways to beat it.Banniza, a professor with the College of Agriculture and Bioresources, received more than $4.2 million from the Strategic Research Initiative (SRI) to uncover solutions for root rot in pea and lentil crops.As Banniza puts it, root rot in pea and lentil has become so prevalent in Western Canada it has caused growers to stop planting the crops in some areas.  See omnystudio.com/listener for privacy information.

SoundStage! Audiophile Podcast
Dr. Floyd Toole: An Oral History 1 - Two Ears and a Brain | Transistors | Rules and Data

SoundStage! Audiophile Podcast

Play Episode Listen Later Jul 5, 2024 56:55


This week, host Jorden Guth is joined by the loudspeaker legend himself, Dr. Floyd Toole, whose research at Canada's National Research Council (NRC), followed by his tenure at Harman International, resulted in arguably more improvements to the fidelity of audio we hear at home than anything attributable to any one person. In this first of our two-part discussion, Dr. Toole discusses his path from university to the NRC and right up to the onset of the Athena project, where we'll pick up in the second part. Sources: “Canada's NRC: A Forthcoming Look at Its Role in the Advancement of Canadian Loudspeaker Design” by Doug Schneider: https://www.soundstagehifi.com/index.php/opinion/1849-canadas-nrc-a-forthcoming-look-at-its-role-in-the-advancement-of-canadian-loudspeaker-design “The Loudspeaker Class of '74: A Canadian Reunion” by Doug Schneider: https://www.soundstagehifi.com/index.php/opinion/1866-the-loudspeaker-class-of-74-a-canadian-reunion “Floyd Toole, NRC, SoundStage!—Filming of Our Upcoming Documentary” by the soundstagenetwork on YouTube: https://youtu.be/k8ykCTEOhZI?si=BfcmIAWg1s6BKyQm Chapters: 00:00:00 Announcement 00:00:28 Introductions 00:04:39 The dawning of the age of the transistor 00:11:05 Two ears and a brain 00:21:28 A fateful interview 00:27:58 Music break: "Turkish March” by T. Bless & the Professionals 00:29:24 Friday afternoon experiments 00:33:54 The differences between musicians and audiophiles 00:38:54 An industry operating without rules 00:49:45 What can we learn from a set of data? 00:54:01 “When I Get Home” by Brian Claxton

The Angus Conversation
Fish Farms, Male Fertility and Angus Cattle — Genetic Innovations of the Present and Future

The Angus Conversation

Play Episode Listen Later Dec 19, 2023 58:58


Could the epigenetics of a male sperm cell tell us anything about cow herd fertility? What advancements in the aquiculture industry could be applied to the beef business? Two scientists give an outside perspective on how technology is shaping improvements in everything from patient care to feeding a growing world population. They share challenges that sound familiar, such as barriers to data collection and applying genetic tools across diverse production environments. This episode is meant to stretch perspectives by showing what is, what could be, and cautions and encouragement for the future. HOSTS: Miranda Reiman and Kelli Retallick-Riley, president, Angus Genetics Inc.GUESTS: Debbie Plouffe, co-founder and vice president of business development-genetics for the Center for Aquaculture Technologies (CAT). The full-service R&D company helps improve productivity, efficiency, and sustainability in the aquaculture industry.  Debbie graduated with a bachelor's in invertebrate biology and a doctorate in physiology and cell biology from the University of Alberta, and she's held leadership roles at the National Research Council (NRC) and AquaBounty Technologies. There she contributed to the regulatory approval of the world's first genetically engineered food animal, the AquAdvantage salmon. She's now based at CAT's San Diego, Calif., office, working with collaborators across the globe on genetic improvement in fish.  Kristin Brogaard, chief scientific officer and co-founder of Inherent Biosciences, leads the design and execution studies that validate their products that focus on using epigenetic discoveries to answer unexplained medical conditions. Currently much of her work focuses on the DNA methylation patterns associated with male infertility.Kristin received her doctorate in molecular biology from Northwestern University, where she developed a novel epigenetic technology that allowed for single-base pair resolution mapping of DNA binding proteins genome-wide. She did postdoctoral work with Leroy Hood, a pioneer in personalized medicine technologies, and then served as director of program management for Arivale before joining Inherent Biosciences in 2019. Co-founding the startup allowed Kristin to combine her passion for epigenetics and personalized medicine to help put a stop to trail-and-error medical procedures. Don't miss news in the Angus breed. Visit www.AngusJournal.net and subscribe to the AJ Daily e-newsletter and our monthly magazine, the Angus Journal.

To The Point - Cybersecurity
Cyber Conundrum: The Higher the Wall, The Higher the Ladder with Herb Lin

To The Point - Cybersecurity

Play Episode Listen Later Apr 12, 2022 48:34


This week we are joined by Herb Lin, Senior Research Scholar, CISAC and Hank J. Holland Fellow, Hoover Institution at Stanford University – and author of the book Cyber Threats and Nuclear Weapons. Herb shares his deep expertise in cyber policy and security to shed light on key questions that should be on everyone's mind, such as “Why are innovation and cybersecurity opposites” and “Why are we always behind in cybersecurity?”. He also breaks down why complexity is the enemy of security, cyber war vs nuclear war, three roads to ruin, and the role of a Chief Luddite Officer. Prepare for your mind to be blown! Herb Lin, Senior Research Scholar at Stanford's Center for International Security and Cooperation Dr. Herb Lin is senior research scholar for cyber policy and security at the Center for International Security and Cooperation and Hank J. Holland Fellow in Cyber Policy and Security at the Hoover Institution, both at Stanford University. His research interests relate broadly to policy-related dimensions of cybersecurity and cyberspace, and he is particularly interested in the use of offensive operations in cyberspace as instruments of national policy and in the security dimensions of information warfare and influence operations on national security. In addition to his positions at Stanford University, he is Chief Scientist, Emeritus for the Computer Science and Telecommunications Board, National Research Council (NRC) of the National Academies, where he served from 1990 through 2014 as study director of major projects on public policy and information technology, and Adjunct Senior Research Scholar and Senior Fellow in Cybersecurity (not in residence) at the Saltzman Institute for War and Peace Studies in the School for International and Public Affairs at Columbia University; and a member of the Science and Security Board of the Bulletin of Atomic Scientists. In 2016, he served on President Obama's Commission on Enhancing National Cybersecurity. Prior to his NRC service, he was a professional staff member and staff scientist for the House Armed Services Committee (1986-1990), where his portfolio included defense policy and arms control issues. He received his doctorate in physics from MIT. For links and resources discussed in this episode, please visit our show notes at https://www.forcepoint.com/govpodcast/e176

HDTV and Home Theater Podcast
Podcast 1034: 2022 CES Innovation Awards

HDTV and Home Theater Podcast

Play Episode Listen Later Jan 14, 2022 43:38


2022 CES Innovation Awards On today's show we rundown some of the 2022 Innovation Award winners. We are discussing products related to home theater and audio as well as the Smart Home for this discussion. The full list can be found here… Headphones & Personal Audio, Portable Media Players & Accessories Introducing the Anker Soundcore Frames—inspired by home audio systems and stylish eyewear. Soundcore Frames have a unique interchangeable frame design and the world's first OpenSurround System for open-ear surround sound which offers users a completely new lifestyle and technology experience. Starting at $199 Experience golden sound from true-wireless earbuds. Using ACAA 2.0, the second generation of the world's first coaxial hybrid driver unit, the Anker Liberty 3 Pro produce stunning sound which has achieved Hi-Res Audio Wireless certification and features Soundcore's innovative HearID ANC for noise cancelling that's tailored to your ears. $169 ROG Cetra TWS Pro in-ear headphones offer wireless and wired connections for total versatility and high-quality sound in a variety of scenarios. It features a hi-res ESS 9281 DAC for true-to-life audio, and an ASUS AI Noise-Canceling Microphone provides crystal clear communications. Also, low-latency wireless connections keep video and audio in-sync for advanced gaming experiences anywhere. The SOUNDFORM Immerse Noise Cancelling Earbuds are high-fidelity earbuds featuring superior sound quality with Hybrid Active Noise Cancellation (ANC), advanced six (6) microphone technology, Bluetooth LE audio in Gaming Mode, and locating features using Apple Find My and the SOUNDFORM app. The SOUNDFORM Immerse earbuds are the next-generation edition of its original earbuds offering introduced in April 2021, one of the first-ever accessories to work with Apple's vast and global Find My network, made up of hundreds of millions of Apple devices. The Soundform Immerse noise-canceling earbuds will launch in the second quarter of 2022 for $180 High Performance Home Audio & Video Nebula Cosmos Laser 4K shines with laser-powered brightness giving consumers the power to stream all day. Powered with ALPD 3.0 technology, the projector is the smallest 4K Android TV home projector, projecting content at 2,400 ANSI Lumens. The Smart Image Adaption Engine reduces setup time to seconds with the following features: Gridless Horizontal and Vertical Auto Keystone Correction, Autofocus, Auto-Obstacle Avoidance, and Screen Alignment. If consumers want to move Cosmos Laser 4K around the home, they can with its easy-to-use handle. Content options are abundant with 7,000+ applications available on the Android TV 10.0 operating system.  The Cosmos Laser 4K will be available for pre-purchase on Kickstarter from Jan. 11 through mid-March for $2,100. The PSB Speakers' Synchrony T600 towers represent the finest application of the brand's "True to Nature" design philosophy. Like all PSB Speakers products, the T600s were designed and engineered at Canada's National Research Council (NRC) by a team of highly regarded acoustic specialists guided by renowned PSB Speakers Founder and Chief Acoustic Designer, Paul Barton. This flagship tower features a new 5-way transitional driver array employing three 6½′′ woofers, a 5¼′′ midrange driver, and a 1′′ titanium dome tweeter, in a heavily braced, four-chamber MDF enclosure and custom IsoAcoustic isolators to deliver an immersive, tonally accurate, true to nature soundscape. $8,000/Pair Immersive, jaw-dropping sound marries up with simple, seamless control, and versatile connectivity in the groundbreaking SVS Prime Wireless Pro Powered Speaker Pair. For the first time, all the benefits of wireless smart speakers with the stunning dynamics and pristine clarity of a complete HiFi system, at a fraction of the cost. The Prime Wireless Pro speakers will be available in March 2022 in black or white finish options and are expected to sell for $799/pair Home Audio & Video Components & Accessories Harman Kardon Citation Amp brings HD streaming to any loudspeaker and supports a multi-channel wireless surround sound system with other HK Citation products. User can play their favorite music via Chromecast built-in™ and AirPlay or connect to a TV via HDMI ARC. The simple and intuitive remote control allows the user to control Amp easily and efficiently. A local website provides detailed configuration options for the user to customize and enjoy the premium sound. No US pricing available but can be found for $1000 AUS ($715 USD) Harman Kardon Citation MultiBeam 1100 is the first soundbar combining MultiBeam™ beam-forming surround sound and up-firing speakers that enable 3D-surround formats like Dolby Atmos enhances the TV sound with best-in-class acoustic performance. With the well-integrated LCD touch screen on the top panel, users can easily set up a Wi-Fi connection and stream music over AirPlay, Chromecast, Alexa MRM, Spotify connect. No US Pricing but can be found for £799.00 ($900 USD) Smart Home Homeowners can take control and give themselves 360° of protection with eufy Security Floodlight Cam 2 Pro. With pan and tilt, consumers can get peace of mind by rotating Floodlight Cam 2 Pro in a full circle and blasting 3,000 ANSI Lumens of brightness without a single blind spot. When something triggers Floodlight Cam 2 Pro, the smart subject lock and tracking follows any suspicious activity. Homeowners can then review tiny details with 2K resolution. The light color temperature is also adjustable to provide the most optimal and aesthetically pleasing viewing. $300 The Niro®2 is a wifi garage controller with an added functionality of the a 2K wifi camera.  Open and close your garage door directly through the app from your smart phone and stream live in 2K HD resolution.  Advanced features such as human shape detection, LED light, and auto motion tracking makes it the perfect home security product for a home. Video Displays The LG 83G2 83-inch 4K OLED TV takes home entertainment to the next level with its enormous screen, true-to-life picture quality, and crystal clear audio and advanced AI-based processing performance. Designed with gamers in mind, the LG 86QNED99 Mini LED TV checks off all the boxes with its stunning picture quality, huge screen, and compelling gaming features. The 86-inch 8K ultra-large screen takes advantage of LG's Mini LED and Quantum Dot NanoCell Color Technology to ensure more precise light control for enhanced picture quality and more accurate color reproduction for dynamic, realistic, and vivid gaming experiences. $4500 The LG 97” G2 is the world's largest 4K OLED TV. At 97” it provides the best realistic sensory experience through its ultra-large OLED screen and 4.2 channels (virtual 7.1.2ch) of 100W of immersive audio. The G2 transforms into a stunning digital canvas when turned off. When not in use, its large screen can display various images, from iconic paintings and works of art to picturesque landscapes and famous landmarks. PORTL is a human-sized, booth-shaped device with a 4K touch screen and high fidelity speakers designed to display live streamed and pre-recorded content. The volumetric presentation gives the viewer the impression that the person or object on screen is 3D. A built in forward camera with motion capability, as well as AI features, can create a fully interactive experience.  

Last Week on Earth with Global Arena Research Institute
#19 Science and Diplomacy with William Colglazier

Last Week on Earth with Global Arena Research Institute

Play Episode Listen Later Sep 6, 2021 38:19


This episode's guest is the American physicist Dr. William Colglazier. With an impressive resume, Colglazier's long career has taken him to the Secretary of State, where he provided scientific and technical expertise and advice in support of the development and implementation of U.S. foreign policy as a Science and Technology Adviser. Today, he is the Editor-in-Chief of Science & Diplomacy and Senior Scholar in the Center for Science Diplomacy at the American Association for Advancement of Science (AAAS).Colglazier got his Ph.D. in theoretical physics at the California Institute of Technology in 1971. He has since then worked at several prestigious institutes such as the Stanford Linear Accelerator Center, the Institute for Advanced Study in Princeton, the Center for Science and International Affairs at Harvard's Kennedy School of Government.  The years before his time at the Secretary of State, he oversaw studies in the U.S. National Academy of Sciences (NAS) and the National Research Council (NRC) to provide independent, objective scientific advice on domestic and international public policy issues.In this episode, Colglazier talks about his way into science and politics and his work to implement the Sustainable Development Goals through science, technology and innovation. He describes the current setbacks to science in public policies such as the Paris Agreement, Iran Nuclear Deal and the unpreparedness of the US in the recent pandemic.Global Arena Research Institute is an independent, non-partisan research organisation that combines the most advanced methods of AI-driven data, scientific and other artificial reasoning capabilities, elevating data science into completely new levels of opportunity. Our goal is to provide unprecedented insights into the nature, impact, and management of globalization in order to improve institutional and governmental as well as business, energy and other sectors' decision making. Our mission is to make the most of organically connecting AI-level reasoning capacities with the human-level critical reasoning capacities for the sake of a better future.

Cyber Security Weekly Podcast
Episode 262 - Cyber Influence and Misinformation – a growing threat in Cyber Space

Cyber Security Weekly Podcast

Play Episode Listen Later May 12, 2021


Interview by Jane Lo, Singapore Correspondent with Dr. Herbert Lin, Senior research scholar, Cyber Policy and Security, Center for International Security and Cooperation; Hank J. Holland Fellow, Cyber Policy and Security, Hoover Institution; and Elected Fellow, American Association for the Advancement of Science. In addition to his positions at Stanford University, Dr. Lin is Chief Scientist, Emeritus for the Computer Science and Telecommunications Board, National Research Council (NRC) of the National Academies, where he served from 1990 through 2014 as study director of major projects on public policy and information technology, and Adjunct Senior Research Scholar and Senior Fellow in Cybersecurity (not in residence) at the Saltzman Institute for War and Peace Studies in the School for International and Public Affairs at Columbia University; and a member of the Science and Security Board of the Bulletin of Atomic Scientists. He served on President Obama’s Commission on Enhancing National Cybersecurity. Prior to his NRC service, he was a professional staff member and staff scientist for the House Armed Services Committee (1986-1990), where his portfolio included defense policy and arms control issues. He received his doctorate in physics from MIT. Dr. Lin’s research interests relate broadly to policy-related dimensions of cybersecurity and cyberspace, and he is particularly interested in and knowledgeable about the use of offensive operations in cyberspace, especially as instruments of national policy. Avocationally, Dr. Lin is a long-time folk and swing dancer and a poor magician. Apart from his work on cyberspace and cybersecurity, he is published in cognitive science, science education, biophysics, and arms control and defense policy. He also consults on K-12 math and science education. In this podcast, Dr Lin discussed cyber influence and the modern phenomenon of misinformation, offering historical perspectives and insights into how technological tools are leveraged in today’s misinformation campaigns. He emphasised the key differences between cyber operations and cyber enabled information operations, where the former (e.g. ransomware) targets computer systems, the latter (misinformation) targets our hearts and minds.  Giving examples observed in the U.S., he noted challenges with implementing effective mitigation measures against misinformation whilst preserving the free flow of ideas. He also addressed some commonly asked questions for deploying misinformation and information warfare as a psychological operation from a national security perspective. With non-stop advances in technology and no-shortage of opportunities to sow misinformation, Dr. Lin also shared his thoughts on the evolution of the threat landscape.  

The REAL David Knight Show
The David Knight Show - Wednesday 10Mar2021

The REAL David Knight Show

Play Episode Listen Later Mar 10, 2021 167:37


Today's Guests: Lawyers' Committee for 9/11 Inquiry Petition to Initiate a Congressional Investigation of Anthrax Attacks —#DarkWinter was the Simulation, Model State Health Emergency Powers Act was the Legislation, but Anthrax attack, was the event used to lay the foundation of dictatorial governors, lockdown and mandatory vaccination w/o #InformedConsent FBI Director Robert Mueller (same one) lead a sham investigation that ignored CIA connections and pinned it on a dead scientist And,  * "Operation Chokepoint", Obama's attempt to financially strangle 2A, is back under Biden to kill 1A * CNN brags about "identity papers" being required (vaccine passports) as China rolls them out * Christian REBUTTAL to campaign demonizing Christian who gather for worship as "unloving of their neighbors" and having "spiritual heart issues" TOPICS by TIMECODE 9:19  the idiotic culture just keeps getting more and more like an idiocracy. 17:03 Operation Chokepoint 38:47 Another GOP Gov takes his boot off our necks (in a week from now) — are we supposed to thank them?  It's just the next step in the plan.  The tyrants are now pushing vaccines 41:57 Masks — the psychological and physical damage to children, the mumbling confusion and the Stockholm Syndrome as people want to continue to wear them even when govt doesn't mandate 54:27 A Christian rebuttal to attacks on those attending in-person worship as “unloving” of their neighbors and having “spiritual heart issues”.  23 reasons to worship God — IN PERSON 1:17:32 Drudge, FOX & CNN are pushing vaccine passports as a positive thing even though CNN begins their report with a movie clip of Nazi's asking for “your identity papers”. Reuters talks about gradually handing back little bits of freedom for those vaxxed, as China rolls out the first vaccine passports 1:34:01 INTERVIEW Lawyers' Committee For 9/11 Inquiry (LCfor911.org) joins to discuss the only attack on Congress using a Weapon of Mass Destruction (WMD biological).   After a botched FBI investigation criticized by National Research Council (NRC) and media across the political spectrum, why is Congress NOT reopening an investigation Find out more about the show and where you can watch it at TheDavidKnightShow.com If you would like to support the show and our family please consider subscribing monthly here: https://www.subscribestar.com/the-david-knight-show Or you can send a donation through, PayPal at:  https://www.paypal.com/paypalme/davidknightshow Venmo at:  venmo@davidknightshow Cash App at:  $davidknightshow BTC to:  bc1qkuec29hkuye4xse9unh7nptvu3y9qmv24vanh7 Mail: David Knight, POB 1323, Elgin, TX 78621

Be Healthy in a Hurry Podcast
Episode 86: Water – What About Fluoride in Our Drinking Water?

Be Healthy in a Hurry Podcast

Play Episode Listen Later Sep 22, 2020 35:56


 Is there dental support evidence or scientific research that supports that fluoridation helps save teeth? What the National Research Council (NRC) says about Fluoride in Drinking Water What the Harvard University School of Dental Medicine says about young children who drink Fluoridated Water. What Fluoride really is  Chief Biochemist of the National Cancer Institute statement on what Fluoridated Drinking Water really does to the body

Stats + Stories
CSI - Crime Stats Investigated | Stats + Stories Episode 4

Stats + Stories

Play Episode Listen Later Jul 31, 2018 31:22


Karen Kafadar, Rudy Professor of Statistics and Physics at Indiana University, joined the Stats+Stories regulars to discuss forensic science, the evidence used help solve crimes. She was a member of a National Research Council (NRC) committee that produced the report Strengthening Forensic Science in the United States: A Path Forward, and she has written on Statistical Issues in Assessing Forensic Evidence.

Medizinische Fakultät - Digitale Hochschulschriften der LMU - Teil 15/19

Background: Childhood overweight has become a growing public health challenge. It has been suggested that inadequate or excessive gestational weight gain (GWG) may result in permanent metabolic and neuronal changes in the developing fetus. Although effects of GWG on birth weight are established, less is known about its effects on the long-term weight status of the child. In 2009, the Institute of Medicine (IOM) and the National Research Council (NRC) published recommendations for trimester-specific and total GWG depending on maternal pre-pregnancy body mass index (BMI). It is unknown, however, how well the trimester-specific IOM/NRC recommendations for GWG identify women at risk of total GWG outside those recommendations. It is also unknown, whether a reverse from excessive GWG in early or mid-pregnancy reduces the risk of childhood overweight. Aims: Contribute to the existing knowledge on the association between GWG and childhood overweight (study 1). Examine whether and to what extent inadequate or excessive total GWG can be predicted in the first, second and third trimester, based on trimester-specific GWG cut-off values (study 2). Investigate whether a reverse from excessive GWG before the third trimester is associated with a risk reduction of childhood overweight (study 3). Methods: A retrospective cohort study was conducted. The sample was recruited prior to the school entry health examinations in 2009 and 2010. Data on maternal weight was derived from medical records and child’s anthropometric data were measured. From 11,730 mother-child pairs available, 6,837 were included in study 1, 7,962 in study 2 and 6,767 in study 3. To investigate the effect of total GWG, overall and stratified by maternal pre-pregnancy BMI, and reverse from excessive GWG in early or mid-pregnancy, multivariate logistic regression analyses were conducted including a large number of potential confounders. Odds ratios (OR) and 95% confidence intervals (CI) were calculated. The prognostic values of lower and upper trimester-specific GWG cut-off values were examined by calculating sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and positive diagnostic likelihood ratio (DLR+). Results: 1) Overall, the risk of childhood overweight increased by 4% per additional kg GWG (OR: 1.04, 95% CI: 1.02, 1.05). Excessive total GWG was associated with a 57 % higher risk of childhood overweight (OR: 1.57, 95% CI: 1.30, 1.91). Stratified by maternal pre-pregnancy BMI, significant associations between excessive GWG and childhood overweight found among normal weight mothers (OR: 1.29, 95% CI: 1.01, 1.66) and overweight mothers (OR: 1.64, 95% CI: 1.06, 2.63). 2) Prediction of total GWG within the IOM/NRC recommendations increased with gestational age and was related to the maternal BMI category and outcome. In trimester two, inadequate total GWG could be predicted with a sensitivity of 49% and 60.2% and a PPV of 72.1% and 68.3% in underweight and normal-weight mothers, respectively. Excessive GWG could be predicted with a sensitivity of 72.7% and 70.4% and a PPV of 94.3% and 93.3% in overweight and obese mothers, respectively. 3) Compared to mothers who always gained below the excessive GWG cut-off values (reference category), children of mothers with excessive GWG in the third and any previous trimester had a 42% higher risk of overweight at school entry (OR: 1.42, 95% CI: 1.17, 1.72). There was a 39% higher risk if mothers gained excessively in the third trimester only (OR: 1.39, 95% CI: 1.06, 1.82). No higher risk was observed for mothers who reversed from excessive GWG before the third trimester compared to reference category. Conclusions: Excessive total GWG appears to be a risk factor for childhood overweight. It can be well predicted from the second trimester on, in particular in overweight and obese women. Reverse from excessive GWG before the third trimester may reduce the risk of childhood overweight. More research is required to further establish the strength of association between GWG and childhood overweight. It appears possible to identify women at risk of gaining outside the recommendations as early as the second trimester. Those women should be allocated to appropriate weight modifying measures. The long-term benefit of GWG modifying measures on childhood overweight, especially a reverse from excessive GWG in the first or second trimester, should be investigated in randomised controlled studies.

Carnegie Science Center Podcast
Cafe Sci Q&A: "Open Forum on the Future of Space Exploration at NASA"

Carnegie Science Center Podcast

Play Episode Listen Later Apr 19, 2011 41:39


John Radzilowicz Director of Science & Education Carnegie Science Center Dan Malerbo Planetarium Education Coordinator Carnegie Science Center Historic Open Forum on the Future of Space Exploration at NASA At the invitation of the National Aeronautics and Space Administration (NASA), Carnegie Science Center is holding this town hall meeting to gather feedback for NASA's consideration in its strategic planning for the next decade of planetary and space science. This is the first time that NASA has asked its volunteer network and affiliates to hold an open forum on such an important topic. Carnegie Science Center is one of a few select locations across the nation employed by NASA to hold this public dialogue. How will it work? Two Science Center staff with extensive expertise in astronomy – John Radzilowicz, and Dan Malerbo – will share the results of the 2013 Planetary Science Decadal Survey, released by the National Research Council (NRC), then solicit and record your feedback on the survey's findings! NASA uses the Decadal Survey to guide its goals and objectives for space research, such as identifying the composition of our solar system, revealing the process that formed our universe, mapping the bio-history of the Earth and its relationship to the Sun, and predicting the future of our environment. NASA has six weeks to respond to the NRC with its reactions to the 2013 Decadal Survey. NASA will then use the data to shape its own 10-year plan for future space endeavors. Join us for this unique and historic opportunity to influence the future of space exploration! Recorded on April 4, 2011 at Carnegie Science Center in Pittsburgh, PA.

Carnegie Science Center Podcast
Cafe Scientifique: "Open Forum on the Future of Space Exploration at NASA"

Carnegie Science Center Podcast

Play Episode Listen Later Apr 19, 2011 65:52


John Radzilowicz Director of Science & Education Carnegie Science Center Dan Malerbo Planetarium Education Coordinator Carnegie Science Center Historic Open Forum on the Future of Space Exploration at NASA At the invitation of the National Aeronautics and Space Administration (NASA), Carnegie Science Center is holding this town hall meeting to gather feedback for NASA's consideration in its strategic planning for the next decade of planetary and space science. This is the first time that NASA has asked its volunteer network and affiliates to hold an open forum on such an important topic. Carnegie Science Center is one of a few select locations across the nation employed by NASA to hold this public dialogue. How will it work? Two Science Center staff with extensive expertise in astronomy – John Radzilowicz, and Dan Malerbo – will share the results of the 2013 Planetary Science Decadal Survey, released by the National Research Council (NRC), then solicit and record your feedback on the survey's findings! NASA uses the Decadal Survey to guide its goals and objectives for space research, such as identifying the composition of our solar system, revealing the process that formed our universe, mapping the bio-history of the Earth and its relationship to the Sun, and predicting the future of our environment. NASA has six weeks to respond to the NRC with its reactions to the 2013 Decadal Survey. NASA will then use the data to shape its own 10-year plan for future space endeavors. Join us for this unique and historic opportunity to influence the future of space exploration! Recorded on April 4, 2011 at Carnegie Science Center in Pittsburgh, PA.