Podcasts about biological technologies department

Join host Carl Brown as he and special guest Dr. John Hannan, Chief of the Digital Battlespace Management Division, in the Defense Threat Reduction Agency's Chemical and Biological Technologies Department, as they discuss the increasingly significant role artificial intelligence and machine learning has in developing protections against current and emerging chemical and biological threats.

Theodora Hatziioannou joins the TWiV team to discuss a macaque model for AIDS, and how a cell protein that blocks HIV-1 infection interacts with double-stranded RNA. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Guest: Theodora Hatziioannou Become a patron of TWiV! Links for this episode ASU-UofA Joint Virology Symposium Laboratory of Retrovirology, Rockefeller University HIV-1-induced AIDS in monkeys (Science) APOBEC3H bound to duplex RNA (Nat Comm) Center for HIV RNA studies Image: Two molecules of APOBEC3H bound to dsRNA This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. Get $30 off your first delivery and FREE SHIPPING by going to blueapron.com/twiv. This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com Weekly Science Picks Theodora - To Kill A Mockingbird by Harper Lee Kathy - 25 MILLION Orbeez in a pool Dickson - Fluid Dynamics of Paint Rich - The Hitchhiker's Guide to the Galaxy by Douglas Adams Alan - 30 days at sea: timelapse Vincent - TWiEVO 24 and Every Time Zone Listener Picks Fernando - Lego Women of NASA Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

At Tufts University Dental School in Boston, Vincent speaks with Katya Heldwein and Sean Whelan about their careers and their work on herpesvirus structure and replication of vesicular stomatitis virus. Host: Vincent Racaniello Guests: Katya Heldwein and Sean Whelan Become a patron of TWiV! Links for this episode Crystal structure of HSV gB (Science) Crystal structure of HSV fusion regulator gH-gL (Nat Struct Mol Biol) Nuclear Exodus: Herpesviruses Lead the Way (Ann Rev Virol) VSV Pseudotypes Bearing gB, gD, gH, and gL (J Virol) Recovery of infectious VSV from cDNA clones (PNAS) Structure of the L Protein of VSV (Cell) Unique strategy for mRNA cap methylation by VSV (PNAS) Molecular architecture of VSV RNA polymerase (PNAS) This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

The TWiViridae review the 2017 Nobel Prizes for cryoEM and circadian rhythms, and discuss modulation of plant virus replication by RNA methylation. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Become a patron of TWiV! Links for this episode Truth Wins by Jonathan Yewdell (epub or mobi) Gabriel Victora awarded MacArthur Prize Forty Years of mRNA Splicing (CSH) 2017 Chemistry Nobel: Jacques Dubochet, Joachim Frank, Richard Henderson 2017 Physiology or Medicine Nobel: Jeffrey C. Hall, Michael Rosbash, Michael W. Young 2017 Nobel Prize in Chemistry (pdf) 2017 Nobel Prize in Physiology of Medicine (pdf) Jonathan Weiner on TWiEVO 19 RNA methylation modulates plant virus infectivity (PNAS) Letters read on TWiV 463 This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. Get $30 off your first delivery and FREE SHIPPING by going to blueapron.com/twiv. This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com Weekly Science Picks Kathy - When biospheres collide Dickson - Blame 10 rivers for ocean plastic Alan - Farming in The Netherlands Vincent - Meet the Microbiologist Listener Picks Jay - OmegaTau podcast Trudy - Arrowsmith by Sinclair Lewis Mark - iOS app Human Anatomy Atlas and Master in Business podcast Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

The TWiM hosts and associated microbiomes review a fungus destroying salamanders in Europe, and genes for flagella in intracellular bacteria. Hosts:  Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter. Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a patron of TWiM. Links for this episode Fungus killing fire salamanders (Nature) Chlamydia with flagella (ISME J) Flagellar movement in rickettsia (PLoS One) Image credit Letters read on TWiM 162 Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com  

Vincent speaks with 1993 Nobel Laureate Phillip A. Sharp about his career and his seminal discovery of RNA splicing in mammalian cells, which changed our understanding of gene structure. Hosts: Vincent Racaniello Guest: Phillip A. Sharp Become a patron of TWiV! Links for this episode Meet the Microbiologist Sharp Laboratory Spliced segments of adenovirus late mRNA (PNAS) Video of this interview (YouTube) This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

The TWiVers discuss the declining readability of scientific texts, and review the use of self-inactivating rabies virus for tracing neural circuits. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Kathy Spindler Guest: Brianne Barker Become a patron of TWiV! Links for this episode Meet the Microbiologist TWiV 1: West Nile Virus Decreasing readability of scientific texts (eLife) Measure text readability Tracing neural circuits with self-inactivating rabies virus (Cell) Cre driver network (NIH) Monosynaptic tracing with rabies virus (Neuron) Letters read on TWiV 461 This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com Weekly Science Picks Kathy -Best eclipse video (to date) and solargraph Dickson - Photos by Will Eades Brianne - Pale Rider by Laura Spinney Rich - “Supergenes” Drive Evolution Vincent -Anatomy of a Moral Panic Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

Vincent travels to the University of Pennsylvania and speaks with virologists Gary Cohen, Scott Hensley, Carolina Lopez, and Susan Weiss about their careers and their research. Host: Vincent Racaniello Guests: Gary Cohen, Scott Hensley, Carolina Lopez, and Susan Weiss Become a patron of TWiV! Links for this episode Cohen Laboratory Hensley Laboratory Lopez Laboratory Weiss Laboratory This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

From the TWiM team, a discussion of Hurricane Harvey microbiology, and a bacterial enzyme that induces eukaryotic mating. Hosts:  Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter. Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a patron of TWiM. Links for this episode Tainted Houston floodwaters (NYTimes) Peter Hotez on TWiP 29 FAQ: Microbiology of Built Environments, American Academy of Microbiology Microbiomes of the Built Environment:  A Research Agenda for Indoor Microbiology, Human Health, and Buildings, The National Academies of Sciences Eukaryotic mating induced by bacterial enzyme (Cell) Image credit: Arielle Woznica Nicole King on TWiEVO 11 Letters read on TWiM 161 Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com

The TWiV team reviews the first FDA approved gene therapy, accidental exposure to poliovirus type 2 in a manufacturing plant, and production of a candidate poliovirus vaccine in plants. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Become a patron of TWiV! Links for this episode ASM Conference on Viral Manipulation of Nuclear Processes ASM Public Outreach Fellowship Kymriah approved (PennMed) CAR T cells (NCBI) Cost of Kymriah (NYTimes) Accidental exposure to poliovirus type 2 (Eurosurveill) GAPIII (WHO) Poliovaccine candidate in plants (Nat Commun) Vertical vaccine farm (TWiV 47) All picornaviruses, all the time (TWiV 425) Image credit Letters read on TWiV 459 This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com Weekly Science Picks Kathy - Cassini photos Dickson - Caliber Biotherapeutics Alan - Grav Rich - Google street view of the International Space Station (article) Vincent - the bioinformatics chat Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

The TWiVians present an imported case of yellow fever in New York City, and explain how a dengue virus subgenomic RNA disrupts immunity in mosquito salivary glands to increase virus replication. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Become a patron of TWiV! Links for this episode ASM Conference on Viral Manipulation of Nuclear Processes Roger W. Hendrix, 74 (Pittsburgh Post-Gazette) Roger Hendrix video on TWiV #135 Yellow fever in traveler returning from Peru (MMWR) Dengue subgenomic RNA in mosquito salivary gland (PLoS Path) Image credit Letters read on TWiV 458 This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com Weekly Science Picks Kathy - Antibody validation Editorial Asilomar meeting report Dickson - Despommierphotoart.com Alan - NOAA Hurricane Hunters Rich - Awakenings by Oliver Sacks (encephalitis lethargica) Vincent - Goodnight Lab by Chris Ferrie Listener Picks Pete - Change Agent by Daniel Suarez Paul - Pasteur's Gambit by Stephen Dando-Collins Maureen - Discovery Documentary First in Human Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

The TWiM team provides an update on Zika virus, and reveals a plasmid on the road to becoming a virus. Hosts:  Vincent Racaniello, Michael Schmidt, and Michele Swanson. Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a patron of TWiM. Links for this episode Regional Zika update, Americas (PAHO, WHO) FGCU, Zika (TWiV 454) CDC Graphic of US zika cases as of May 2017 Archaeal plasmid travels cell to cell via vesicles (Nature Micro) Letters read on TWiM 160 Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com

Brianne returns to the TWiV Gang to discuss the distribution of proteins on the influenza viral genome, and the evolution of myxoma virus that was released in Australia to control the rabbit population. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit Guest: Brianne Barker Become a patron of TWiV! Links for this episode First genetically engineered salmon sold in Canada Nucleoprotein on influenza virus RNA (Nucl Acids Res) Evolution of released myxoma virus in Australia (PNAS) Image credit Letters read on TWiV 457 This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free with your first purchase - WITH FREE SHIPPING - by going to blueapron.com/twiv. This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com Weekly Science Picks Brianne - 3D printed viruses Dickson - Secrets of Schooling Alan - Making sails in the Nevada desert Rich - David Vetter isolation suit (Wiki) Vincent - Confounds the Science Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

Brianne joins the TWiVMasters to explain how mutations in genes encoding RNA polymerase III predispose children to severe varicella, and detection of an RNA virus by a DNA sensor. Hosts: Vincent Racaniello and Rich Condit Guest: Brianne Barker Become a patron of TWiV! Links for this episode RNA pol III mutations underlie severe varicella (J Clin Inves) Dengue virus activates cGAS by release of mitochondrial DNA (Sci Rep) Dengue virus NS2B protein targets cGAS for degradation (Nat Micr) Image credit Letters read on TWiV 456 This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com Weekly Science Picks Brianne - Up-Goer Five Challenge (related to Thing Explainer) Rich - The Farthest: Voyager in Space and Vipassana Momma: Science Vincent - Episode of Revisionist History: The Basement Tapes Listener Pick Jennie - What Piece of Lab Equipment Are You? Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

Erin joins the TWiVirions to discuss a computer exploit encoded in DNA, creation of pigs free of endogenous retroviruses, and mutations in the gene encoding an innate sensor of RNA in children with severe viral respiratory disease. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Guest: Erin Garcia Become a patron of TWiV! Links for this episode DNA-based computer exploit (pdf) Inactivation of porcine endogenous retrovirus in pigs (Science) Severe viral respiratory infections in children with IFIH1 mutations (PNAS) IRF7 deficiency and severe respiratory infection (TWiV 336) Image credit Letters read on TWiV 455 This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at http://www.cbdstconference.com Weekly Science Picks Erin - What If? by Randall Monroe Rich - Art.Science.Gallery (J. Haley Gillespie) Kathy - Astronomy photographer of the year shortlist Alan - Upcoming Eclipses Vincent - Ford Thunderbird Automatic Transmission Rebuild Listener Pick Bryan - Neuroscientists tricks journals Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

An attack that seems to come from nowhere and advances like a silent predator creeping on its prey, through the ranks of troops and civilians alike – that is the fear a biological attack or emerging disease event brings: an unseen enemy striking without warning. Researchers from the Defense Threat Reduction Agency’s Chemical and Biological Technologies Department are working with other U.S. government, state, and local agencies to be able to make these unseen enemies visible by strengthening the Nation’s biosurveillance capabilities to provide early warning notification to warfighters and first responders.