Podcasts about neurobiology

TWiN explains how visual neurons show functional flexibility by selectively responding to subsets of inputs representing attended objects while ignoring those conveying information about irrelevant objects. Hosts: Vincent Racaniello, Vivianne Morrison, and Tim Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode MicrobeTV Discord Server Gamma-band synchronization in visual cortex (Nat Comm) Timestamps by Jolene Ramsey. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv

Sign up for updates on webinars, events, and resources for the Parkinson's community—delivered to your inbox. https://dpf.org/newsletter-signup In the final episode of this three-part series, Connie Carpenter Phinney and Dr. Mark Mapstone explore the emotional and cognitive changes that can occur as Parkinson's progresses. They talk openly about issues like apathy, anxiety, executive function decline, and how these changes can affect relationships, communication, safety, and daily life—including decisions around driving and independence. While the conversation acknowledges grief, frustration, and loss, it also offers insight, practical advice, and strategies for living well through change. This episode is for anyone facing or seeking to understand the emotional and cognitive realities of Parkinson's—people diagnosed, care partners, and clinicians alike. Connie Carpenter Phinney is a co-founder of the Davis Phinney Foundation and has been her husband's care partner for over 25 years. Her background in science combined with her lived experience and curiosity helped shape this conversation with neuropsychologist Dr. Mark Mapstone. Connie is the host of the Foundation's Care Partner Meetup, a monthly virtual meetup for Parkinson's care partners held the first Tuesday of each month. To attend the meetup, sign up here: https://davisphinneyfoundation.org/events/parkinsons-care-partner-meetup/ Dr. Mark Mapstone is Professor of Neurology at the University of California, Irvine School of Medicine. He is a member of the UCI Institute for Memory Impairments and Neurological Disorders and a Fellow of the UCI Center for Neurobiology of Learning and Memory. His research focuses on pre-clinical detection of neurological disease using cognitive tests and biomarkers obtained from blood. He has a special interest in developing strategies to maintain successful cognitive aging. In the clinic, he specializes in cognitive assessment of older adults with suspected brain disease. Dr. Mapstone earned a PhD in Clinical Psychology at Northwestern University and completed fellowship training in Neuropsychology and Experimental Therapeutics at the University of Rochester. He received a Career Development Award from the National Institute on Aging and his research has been funded by the National Institutes of Health, the Michael J. Fox Foundation, and the Department of Defense. This content is possible thanks to the generosity of our listeners. Every day more people are diagnosed with Parkinson's, and this means our work is more important than ever. Please support our work by visiting https://dpf.org/donate. Interested in our Living with Parkinson's Meetup, Care Partner Meetup, or Live Well Today Webinars? Learn how to join. https://dpf.org/webinars

Imagine waking up to find your company's most valuable IP leaked—not by hackers, but by the very AI tools you trusted.This isn't a distant scenario; it's happening inside pharma and biotech right now.And the cost isn't just financial—it's patient lives, broken trust, and an industry on the edge of losing credibility. In this episode, Kat Kozyrytska shares how leaders can act before invisible risks become catastrophic. From her personal journey in post-Soviet Ukraine to building frameworks in global biotech, Kat reveals why “yesterday problems” with AI demand urgent attention today.You'll learn how data privacy failures propagate quietly, why embedding organizational values into AI is essential, and how collaboration across companies can safeguard innovation and accelerate therapies. The future of biotech won't be secured by hype or speed—but by trust, ethics, and the courage to act before it's too late. 

What if empathy isn't gone—just thirsty—and the rehydration begins in your nervous system and  our emotional bodies? We sit down with author, neuroscience educator, and my teacher, Sarah Peyton, to explore accompaniment, the body-based practice of bringing your full self into relationship and letting resonance change you. From the rise of fascism to climate grief and information overload, we trace how overwhelm disconnects us from a healthy, sacred NO—and how tending to our disgust circuit becomes an inoculation to the manipulation, scapegoating, and burnout. We talk about unconscious contracts and how to spot, revoke, and replace them with life‑honoring vows. Along the way, we surface the baked-in conditioning culture has trained us to direct disgust at people instead of the harms done to them, and we share practical steps to reorient toward collective care and courage, empathy and agency.♨ show notes from the jacuzzi-verse ♨Free grounding meditation with Dana—a practice of calling your energy back/nervous system tending/reclaiming your attention) ~ (http://bit.ly/grounding-now)Enter to win a free coaching session ~ when you leave a 5-star rating (only) and a written review, you'll be entered into a monthly drawing for a free 90-min coaching session with dana (value of $388). Send the name of your review (title and/or reviewer name) via IG @danablix or email dana@ danabalicki .com ~ Winner announcements will be made across platforms mid-month.

Before the written word — and possibly even before speech — humans have communicated through drawing. From crude scratches in the dirt or on cave walls to the arcane symbology of the laboratory whiteboard, our instinct for conveying our thoughts visually is pretty extraordinary. We see or understand something in the world, we build an idea in our mind of what we think we see, and then using our hand and the utensil we re-create it to communicate the share our perception with others. Along the way, we add in our own understanding and experience to craft that communication in ways that might not correspond with a specific object in the world at all.How we do this — and how we can learn to be better visual communicators — is at the heart of our conversation with Judy Fan, who runs the Cognitive Tools Lab in Stanford University's Department of Psychology.We've been nominated for a 2025 Signal Award for Best Science & Education Podcast! Vote for us in the "Listener's Choice" category by October 9.Learn More:Cognitive Tools Lab, Stanford Department of PsychologyFan, J., et al. (2023) "Drawing as a versatile cognitive tool." Nature Reviews Psychology. (pdf)Hawkins, R., Sano, M., Goodman, N., and Fan, J. (2023). Visual resemblance and interaction history jointly constrain pictorial meaning. Nature Communications. [pdf]Fan, J., et al. (2020). Relating visual production and recognition of objects in human visual cortex. Journal of Neuroscience. [pdf]Fan, J., Yamins, D., and Turk-Browne, N. (2018). Common object representations for visual production and recognition. Cognitive Science. [pdf]More recent papersWe want to hear from your neurons! Email us at at neuronspodcast@stanford.eduSend us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.

Sign up for updates on webinars, events, and resources for the Parkinson's community—delivered to your inbox. https://dpf.org/newsletter-signup In this episode, Connie and Dr. Mapstone dive into the role of neuropsychology in Parkinson's care. They explain what a neuropsychological evaluation is, what to expect during an office or virtual visit, and how results can help guide treatment, daily planning, and care strategies. This episode also discusses why someone might be referred, how testing works, and what insights it can offer for both individuals and families. **This content is possible thanks to the generosity of our listeners. Every day more people are diagnosed with Parkinson's, and this means our work is more important than ever. Please support our work by visiting https://dpf.org/donate.** Connie Carpenter Phinney Connie Carpenter Phinney is a co-founder of the Davis Phinney Foundation and has been her husband's care partner for over 25 years. Her background in science combined with her lived experience and curiosity helped shape this conversation with neuropsychologist Dr. Mark Mapstone. Connie is the host of the Foundation's Care Partner Meetup, a monthly virtual meetup for Parkinson's care partners held the first Tuesday of each month. To attend the meetup, sign up here: https://davisphinneyfoundation.org/events/parkinsons-care-partner-meetup/ Dr. Mark Mapstone Mark Mapstone is Professor of Neurology at the University of California, Irvine School of Medicine. He is a member of the UCI Institute for Memory Impairments and Neurological Disorders and a Fellow of the UCI Center for Neurobiology of Learning and Memory. His research focuses on pre-clinical detection of neurological disease using cognitive tests and biomarkers obtained from blood. He has a special interest in developing strategies to maintain successful cognitive aging. In the clinic, he specializes in cognitive assessment of older adults with suspected brain disease. Dr. Mapstone earned a PhD in Clinical Psychology at Northwestern University and completed fellowship training in Neuropsychology and Experimental Therapeutics at the University of Rochester. He received a Career Development Award from the National Institute on Aging and his research has been funded by the National Institutes of Health, the Michael J. Fox Foundation, and the Department of Defense. Interested in our Living with Parkinson's Meetup, Care Partner Meetup, or Live Well Today Webinars? Learn how to join. https://dpf.org/webinars

Despite the many psychedelics clinical trials underway, there is still much we don't know about how these drugs work. Preclinical studies represent our best viable avenue to answer these lingering questions.

Sign up for updates on webinars, events, and resources for the Parkinson's community—delivered to your inbox. https://dpf.org/newsletter-signup In the first episode of our three-part series about neuropsychology and Parkinson's, Connie Carpenter Phinney and Dr. Mark Mapstone explore how brain chemistry, especially dopamine, relates to thinking, movement, and mood in Parkinson's. They break down key terms like cognition and executive function and offer insights into how Parkinson's affects brain systems beyond motor symptoms. This episode lays the groundwork for understanding how the brain works—and what happens when it changes. **This content is possible thanks to the generosity of our listeners. Every day more people are diagnosed with Parkinson's, and this means our work is more important than ever. Please support our work by visiting https://dpf.org/donate.** Interested in our Living with Parkinson's Meetup, Care Partner Meetup, or Live Well Today Webinars? Learn how to join. https://dpf.org/webinars Visit https://dpf.org to learn more about the Davis Phinney Foundation for Parkinson's. Speaker Bios: Connie Carpenter Phinney Connie Carpenter Phinney is a co-founder of the Davis Phinney Foundation and has been her husband's care partner for over 25 years. Her background in science combined with her lived experience and curiosity helped shape this conversation with neuropsychologist Dr. Mark Mapstone. Connie is the host of the Foundation's Care Partner Meetup, a monthly virtual meetup for Parkinson's care partners held the first Tuesday of each month. To attend the meetup, sign up here: https://davisphinneyfoundation.org/events/parkinsons-care-partner-meetup/ Dr. Mark Mapstone Mark Mapstone is Professor of Neurology at the University of California, Irvine School of Medicine. He is a member of the UCI Institute for Memory Impairments and Neurological Disorders and a Fellow of the UCI Center for Neurobiology of Learning and Memory. His research focuses on pre-clinical detection of neurological disease using cognitive tests and biomarkers obtained from blood. He has a special interest in developing strategies to maintain successful cognitive aging. In the clinic, he specializes in cognitive assessment of older adults with suspected brain disease. Dr. Mapstone earned a PhD in Clinical Psychology at Northwestern University and completed fellowship training in Neuropsychology and Experimental Therapeutics at the University of Rochester. He received a Career Development Award from the National Institute on Aging and his research has been funded by the National Institutes of Health, the Michael J. Fox Foundation, and the Department of Defense.

Why do we get goosebumps, racing hearts, and shaky hands when we're scared? In this episode, we explore the fascinating biology behind fear — from the amygdala's alarm system to the “fight-or-flight” response that helped our ancestors survive. You'll discover how fear is stored in memory, why some people chase thrills, and how scientists are learning to rewire fear responses to help those with trauma. Whether it's facing a wild animal or stepping onto a rollercoaster, fear is both a lifesaving instinct and, surprisingly, a source of pleasure. This episode was prepared with the help of AI, and the content is written by OYLA authors. For subscription, please visit: oyla.us, oyla.uk, oyla.au, oyla.eu, oyla.co.in to check it out!

Birds do the darnedest things. They fly, of course. They sing. They hunt in pitch darkness. They hide their food and remember where they put it. They use tools and migrate over astonishingly vast distances—sometimes even sleeping while in flight. How do they do all this? What's going on in their brains that makes these and other remarkable behaviors possible? How did their evolutionary path mold them into the incredible creatures they are today? My guests today are Dr. Andrew Iwaniuk and Dr. Georg Striedter. Andrew is a comparative neuroscientist and Associate Professor at the University of Lethbridge in Canada. Georg is a Professor of Neurobiology and Behavior at the University of California, Irvine. Together they are the authors of the new book, Bird Brains and Behavior: A Synthesis (available open access here). Here, Georg, Andrew, and I consider the deep history of birds—how they skirted the mass extinction event that felled the dinosaurs, and then radiated out into the 11,000 plus species we know today. We talk about how bird brains differ from those of mammals and reptiles—in terms of their size, but also in terms of their major structures, and in terms of their wrinkliness. We tour some of the most peculiar and perplexing bird behaviors, and consider their neural and anatomical underpinnings. Finally, we consider what we can learn from bird brains, not just about birds but about brains in general—how they evolve, how they get wired up, how they do and do not vary. Along the way we touch on barn owls, hummingbirds, megapodes, mallards, pigeons, parrots, starlings, and underestimated waterfowl; we touch on how birds' brains change with the seasons; the enduring mystery of magnetoreception; the possibility of olfactory maps; the optocollic reflex; the social intelligence hypothesis and the extractive foraging hypothesis; precocial versus altricial bird species; split-body gynandromorphy; and the future of non-invasive work in bird neuroscience. Season 7 of Many Minds is now gathering steam. We've got some great episodes in the works for you. Just a little reminder that we'd be grateful—thrilled, even—if you could help us get the word out about our show. You might do this by leaving a rating or a review, or by telling a colleague about us. We really appreciate the support, friends! Without further ado, here's my conversation with Dr. Georg Striedter and Dr. Andrew Iwaniuk. Enjoy!   Notes 8:00 – For more on the deep history of the brains of birds and other vertebrates, see: Dr. Striedter's book (co-authored with R. Glenn Northcutt), Brains Through Time; this paper authored by Dr. Striedter and colleagues; and this paper authored by Dr. Iwaniuk and colleagues. 9:30 – The paper on neuron density in birds, by Dr. Pavel Němec and colleagues. 20:00 – For more about Dr. Striedter and colleagues revising some of the terminology for bird brain structures, see here and here. 24:00 – A paper by Dr. Striedter and colleagues on cortical folding.  34:00 – A recent paper describing seasonal neurogenesis in European starlings. 38:00 – A paper on the phenomenon of unihemispheric sleep across species. 42:00 – A video demonstrating the optocollic reflex in a bird. 45:00 – A paper on the puzzles of magnetoreception in birds and other animals. 51:00 – A classic paper on sound localization in barn owls.  54:00 – A paper by Dr. Iwaniuk and colleagues showing that harriers have an auditory system much like the (better-studied) owl. 58:00 – For more on place cells, the hippocampus, and cognitive maps, see our previous episode with Dr. Hugo Spiers. For more on the evolution of the hippocampus in birds and reptiles, see Dr. Striedter's paper here. 1:02:00 – For images of gynandromorphy in birds, see here and here. 1:10:00 – For a recent paper on “parental provisioning,” the precocial-altricial spectrum, and brain size in birds, see here. 1:13:00 – For examples of research on the social intelligence hypothesis in birds and other animals, see here and here. 1:18:00 – For work by Dr. Iwaniuk and colleagues on some of the most interesting features of parrot brains, see here. 1:27:00 – The Avonet database.   Recommendations Flight Paths, by Rebecca Heisman An Immense World, by Ed Yong [former guest!] Mind of the Raven, by Bernd Heinrich Bird Brain, by Nathan Emery Soul Made Flesh, by Carl Zimmer   Many Minds is a project of the Diverse Intelligences Summer Institute, which is made possible by a generous grant from the John Templeton Foundation to Indiana University. The show is hosted and produced by Kensy Cooperrider, with help from Assistant Producer Urte Laukaityte and with creative support from DISI Directors Erica Cartmill and Jacob Foster. Our artwork is by Ben Oldroyd. Subscribe to Many Minds on Apple, Stitcher, Spotify, Pocket Casts, Google Play, or wherever you listen to podcasts. You can also now subscribe to the Many Minds newsletter here! We welcome your comments, questions, and suggestions. Feel free to email us at: manymindspodcast@gmail.com. For updates about the show, visit our website or follow us on Bluesky (@manymindspod.bsky.social).

Today's episode continues with visual thinking. We will learn more about the accelerated learning patterns with visual thinking and the Autistic phenotype. Autistic individuals create detailed mental "catalogs" of images and experiences, much like AI's data processing. We explore Temple Grandin's vivid descriptions of thinking in pictures, alongside early observations from Kanner (1943) and Asperger (1944), who noted autistic intelligence in their "little professors." The discussion covers weak central coherence theory & specific details drives exceptional learning but can complicate social interactions and broader contextual understanding.We will discuss the Autistic brain and machine learning, from pattern recognition to iterative refinement. Enhanced neural connections, like those linking the visual and frontal cortex, enable Autistic individuals to excel in tasks requiring precision, such as spotting subtle differences or memorizing facts. The episode contrasts this unique cognitive style with societal norms, advocating for embracing these strengths.Frith & Happe Weak Central Coherence https://link.springer.com/article/10.1007/s10803-005-0039-0Visual Thinking part 1: Neurobiology & Autistic's Intense Inner World https://youtu.be/XqQ8jCvWzYc?si=3cEIm1omi0JUAKSKDaylight Computer Companyuse "autism" for $50 off athttps://buy.daylightcomputer.com/autismChroma Light Devicesuse "autism" for 10% discount athttps://getchroma.co/?ref=autism00:00 - Introduction to Visual Thinking; "movies" in the mind, and its impact on learning.02:02 - Historical Context of Autism References to Leo Kanner (1943) and Hans Asperger (1944) highlight early observations of autistic intelligence, with terms like "little professors" and "autism" (from "autos," meaning self)04:01 - Social Norms vs. Autistic Phenotype The autistic cognitive style contrasts with societal expectations, which favor fitting individuals into predictable "boxes" for evaluation and acceptance, making social integration and education challenging for autistic individuals.06:01 - Cataloging and AI Parallels; mental catalogs & specific images or experiences, similar to AI & machine learning, catalogs for categories08:46 Weak Central Coherence Theory; local, detail-oriented processing over global integration, enabling strengths like spotting hidden shapes10:28 Enhanced Perceptual Functioning, visual and auditory domains, allowing precise cataloging of sensory details, tasks & precision.12:02 Anecdotal Person Comparison & Associative Learning15:30 Pattern Recognition and Detail Focus18:26 Types of Visual Thinkers20:36 Neural Connectivity23:22 Perceptual Learning and Neuroplasticity; Accelerated learning27:04 AI and Autistic Brain Similarities33:35 Daylight Computer Company (and Daylight Kids !), use "autism" for $50 discount35:53 Chroma Light Devices, use "autism" for 10% discount38:59 Don't underestimate this Autistic Phenotype.X: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

Today's episode is all about visual thinking. We will explore vivid mental imagery and sensory processing. We will cover why Autistic individuals process detailed "pictures and movies" in the mind, exemplified by an anecdote of visualizing oak tree bark with tactile detail. Sensory challenges are highlighted, with a Bee Movie analogy illustrating the intense, efficient visual input. The Autistic sensory journey is described as fast but rocky, contrasting with non-autistic processing. Hyperconnectivity in visual pathways amplifies detail-oriented cognition, often leading to sensory overload.The episode explains how retinal ganglion cells and visual cortex hyperactivity enhance imagery in Autism. Kanner and Asperger's observations underscore visual memory strengths and technical interests, like pattern recognition. Increased mini-column density and reduced inhibition boost local processing but risk overload. Temple Grandin's insights show visual thinking's strengths in tasks like designing animal pathways, though social tasks challenge due to weaker prefrontal connectivity. The Autistic brain's wiring is framed as a unique strength, fostering intense, detailed cognitionTemple Grandin https://www.templegrandin.com/templegrandinbooks.htmlSensory Processing part 1 https://youtu.be/HTnFm8nY4oY?si=4Xso_tI_hMwhY_SXSensory Processing part 2 https://youtu.be/n31gyLb4ddM?si=CouaBhiVm8KixtG-Supplementing Relationships part 1 https://youtu.be/lglEGQ7pSlc?si=ncpla784LxOyUcQcSupplementing Relationships part 2 https://youtu.be/W8E2B7Qu4mg?si=UJE850SwvPmtOmEkDaylight Computer Companyuse "autism" for $50 off athttps://buy.daylightcomputer.com/autismChroma Light Devicesuse "autism" for 10% discount athttps://getchroma.co/?ref=autism00:00 Introduction to Visual Thinking02:00 Anecdote: Oak Tree Visualization; tree bark, tactile05:50 Sensory Processing Challenges; overload, information rate, avoidance09:40 Anecdote: Bee Movie Analogy; synchronized, intense, fast13:30 Autistic Sensory Rates/Speeds17:20 Eye Biology and Neural Relays; Retinal ganglion, SHANK3; Building Models details-to-general21:10 Magnocellular vs. Parvocellular Pathways; Motion, color, glutamate, GABA signaling25:00 Visual Cortex Hyperactivity; V1-V4, fMRI, synaptic pruning, details28:50 Mini-Columns and Sensory Overload; Neural units, inhibition, dense connections32:40 Kanner and Asperger Insights; Social isolation, technical interests, patterns38:39 Daylight Computer Company (and Daylight KIDS !), use "autism" for $50 discount40:54 Chroma Light Devices, use "autism" for 10% discount44:07 Reviews/Ratings & Contact InfoX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

My guest is Dr. Christof Koch, PhD, a pioneering researcher on the topic of consciousness, an investigator at the Allen Institute for Brain Science and the chief scientist at the Tiny Blue Dot Foundation. We discuss the neuroscience of consciousness—how it arises in our brain, how it shapes our identity and how we can modify and expand it. Dr. Koch explains how we all experience life through a unique “perception box,” which holds our beliefs, our memories and thus our biases about reality. We discuss how human consciousness is changed by meditation, non-sleep deep rest, psychedelics, dreams and virtual reality. We also discuss neuroplasticity (rewiring the brain), flow states and the ever-changing but also persistent aspect of the “collective consciousness” of humanity. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AGZ by AG1: https://drinkagz.com/huberman BetterHelp: https://betterhelp.com/huberman Our Place: https://fromourplace.com/huberman Helix: https://helixsleep.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps (0:00) Christof Koch (2:31) Consciousness; Self, Flow States (8:02) NSDR, Yoga Nidra, Liminal States; State of Being, Intelligence vs Consciousness (13:14) Sponsors: BetterHelp & Our Place (15:53) Self, Derealization, Psychedelics; Selflessness & Flow States (19:53) Transformative Experience, VR, Racism & Self; Perception Box, Bayesian Model (28:29) Oliver Sacks, Empathy & Animals (34:01) Changing Outlook on Life, Tool: Belief & Agency (37:48) Sponsors: AGZ by AG1 & Helix Sleep (40:23) Alcoholics Anonymous (AA) & Higher Power (42:09) Neurobiology of Consciousness; Accidents, Covert Consciousness (51:09) Non-Responsive State; Disability Bias, Will to Live, Resilience (55:34) Will to Live, Akinetic Mutism, Neural Correlates of Consciousness (57:43) Conflicting Perception Boxes, Meta Prior, Religion, AI (1:06:47) AI, Violence, Swapping Perception Boxes, Video (1:12:19) 5-MeO-DMT, Psychedelics, Light, Consciousness & Awe; Loss of Self (1:20:54) Death, Mystical Experience, Ocean Analogy; Physicalism & Observer (1:27:57) Sponsor: LMNT (1:29:29) Meditation, Tool: Spacetime Bridging; Ball-bearing Analogy; Digital Twin (1:36:16) Mental Health Decline, Social Media, Pandemic, Family & Play, Tool: Body-Awareness Exercises (1:41:34) Dog Breeds; Movement, Cognitive Flexibility & Longevity (1:47:17) Cynicism, Ketamine, Tool: Belief Effect; Heroes & Finding Flaws (1:52:46) Cynicism vs Curiosity, Compassion; Deaths of Despair, Mental Health Crisis (1:57:26) Jennifer Aniston, Recognition & Neurons; Grandmother Hypothesis (2:03:20) Book Recommendation; Meaning of Life (2:09:10) Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

ReferencesMol Neurobiol. 2019 Oct 8;57(2):910–925.Neural Regen Res. 2025 Apr 29;21(3):1037–1057.Open Biol. 2017 May 31;7(5):170069.Neurobiology of Disease 2025. v.207, April , 106852Chamber, W&J.1966 Time Has Come Today. Chambers Brothers. https://music.youtube.com/watch?v=4GPh7PLjUs4&si=N42P6DJJBBOjbPIrRagovoy and Meade. 1963. Time is on my Side. Rolling Stones.https://music.youtube.com/watch?v=ZHKz7FBUF1w&si=GdRI9xB7q_pOWY9vRogers/Slade/Mann 1975.Time is Right. Manfred Mannhttps://music.youtube.com/watch?v=WKtbbCB0Nm8&si=2J5ef4X0zO-PrKRVWaters/Gilmour/Mason/Wright 1973. Time. Pink Floyd. DSotMhttps://music.youtube.com/watch?v=yl-Ms_ek-kE&si=44M9K5WUf24LssAO

On today’s episode, we interview Dr. Brian Erkkila, the Director of Regulatory Science at Swedish Match North America, a subsidiary of Philip Morris International – makers of ZYN. A former scientist at the Food and Drug Administration’s (FDA) Center for Tobacco Products, Dr. Erkkila offers detailed insights on a new generation of smoke-free products and outlines opportunities for tobacco harm reduction. He also addresses common misconceptions about nicotine and explains how the FDA can do more to arm medical professionals with better advice for their patients who smoke. PMI U.S. recently released a white paper on the topic entitled "Getting Smart on Reduced Harm." Dr. Brian Erkkila is a regulatory scientist with a history of tackling complex regulatory issues, specializing in human health risk assessment, pharmacology, tobacco regulation, database development and science policy. He currently serves as the director of regulatory science at Swedish Match North America, a wholly owned subsidiary of Philip Morris International. Prior to this role, he worked at the Foundation for a Smoke-Free World, the Food and Drug Administration’s (FDA) Center for Tobacco Products, Office of Science, and the National Institutes of Health (NIH). Erkkila holds a BA in Neurobiology from The Johns Hopkins University and earned his PhD in Neurobiology from the University of Alabama at Birmingham. See omnystudio.com/listener for privacy information.

This and all episodes at: https://aiandyou.net/ .     I'm talking with Megan Peters, who researches thinking about thinking, or metacognition. She is an Associate Professor in the UC Irvine Department of Cognitive Sciences, studying how the brain represents and uses uncertainty, focusing on how these abilities support metacognitive evaluations of the quality of our decisions. She's a Fellow in the UCI Center for the Neurobiology of Learning and Memory, the UCI Center for Theoretical Behavioral Sciences, and the Canadian Institute for Advanced Research (CIFAR) Brain Mind & Consciousness program. She's also President and Co-founder of Neuromatch, an educational platform serving over 30,000 students in over 120 countries across computational neurosciences, deep learning, computational climate science, and neuroAI. In our conclusion, we talk about Turing Tests, measuring the brain, the Haunted Mansion, some cool experiments on brains, and… cats. All this plus our usual look at today's AI headlines. Transcript and URLs referenced at HumanCusp Blog.            

Dr Tatkin is a clinician, researcher, teacher, and developer of the psychobiological approach to couples therapy, often referred to as PACT. He is assistant clinical professor in the family medicine department at the University of California. Dr Tatkin has authored numerous bestselling books on attachment and couples therapy, including: Wired for Love, Wired for Dating, In Each Other's Care, and Your Brain on Love. In this conversation, we explore: — How human beings behave according to procedural memory most of the time and why this is important to understand in couples work — Why relationships can be so difficult for humans — The difference between a secure functioning relationship and secure attachment And more. You can learn more about Dr Tatkin's work by visiting: thepactinstitute.com --- Stan Tatkin, PsyD, MFT, is a best-selling author, clinician, researcher, teacher, and developer of a Psychobiological Approach to Couple Therapy® (PACT). He has a clinical practice in Calabasas, CA, where he has specialized for the last 15 years in working with couples and individuals who wish to be in relationships. He and his wife, Tracey Boldemann-Tatkin, developed the PACT Institute to train clinicians to help challenging couples find secure-functioning relationships. He is the author of best-selling books We Do, Wired for Love, Wired for Dating and Love and War in Intimate Relationships, as well as the audio books Your Brain on Love and Relationship Rx. Dr. Tatkin also teaches family medicine residents at Kaiser Permanente, Woodland Hills, CA, and is an assistant clinical professor at the UCLA David Geffen School of Medicine, Department of Family Medicine. He travels throughout the United States and abroad with the PACT Institute teaching therapists how to help couples build secure-functioning relationships. --- 3 Books Dr Stan Tatkin Recommends Every Therapist Should Read: — Handbook of Attachment: Theory, Research, and Clinical Applications - Jude Cassidy - https://amzn.to/4aIbYGJ — Lyons-Ruth, K., L. Dutra, M. R. Schuder, and I. Bianchi. 2006. "From Infant Attachment Disorganization to Adult Dissociation: Relational Adaptations or Traumatic Experiences?" Psychiatric Clinics of North America 29 (1): 63–86. - https://psycnet.apa.org/record/2006-03379-005 — Schore, A. N. 2000. "Attachment and the regulation of the right brain." Attachment & Human Development 1 (2): 23–47. - https://www.allanschore.com/pdf/SchoreAttachHumDev.pdf

Dr. Hancock was raised in the San Francisco Bay Area, where she was active in Pony Club, competing in lower level three day eventing. Dr. Hancock completed her studies at Colorado State University, graduating with a BS in Equine Science, an MS in Anatomy and Neurobiology, and a Doctorate of Veterinary Medicine in 2003. She spent 10 years as general equine practitioner in Eastern North Carolina where she built her skills in emergency, dentistry, performance horse and lameness evaluation, reproduction, preventative medicine and integrative health. She also trained with the International Veterinary Acupuncture Society and completed her EDO certification with the Vluggen Institute to become an equine osteopath. Eager to offer progressive and superior services, she continually strives to improve her veterinary diagnostic, integrative medicine, and performance horse education. In 2013, Dr. Hancock purchased Rectortown Equine and permanently relocated the practice to Warrenton, Virginia at which point the practice changed to True North Equine Veterinary Services. Dr. Hancock's goal is to nurture successful partnerships with horses and their owners that can last a lifetime.

This and all episodes at: https://aiandyou.net/ . Have you ever thought about thinking? That's called metacognition, and Megan Peters thinks about that, a lot. She is an Associate Professor in the UC Irvine Department of Cognitive Sciences, researching how the brain represents and uses uncertainty, focusing on how these abilities support metacognitive evaluations of the quality of our decisions. She's a Fellow in the UCI Center for the Neurobiology of Learning and Memory, the UCI Center for Theoretical Behavioral Sciences, and the Canadian Institute for Advanced Research (CIFAR) Brain Mind & Consciousness program. She's also President and Co-founder of Neuromatch, an educational platform serving over 30,000 students in over 120 countries across computational neurosciences, deep learning, computational climate science, and neuroAI. We get really meta here: talking about thinking about thinking,  how we build models of the world, how language shapes our thinking, whether AI is doing metacognition in its chains of thought, statistical learning in AIs and humans, consciousness in humans and animals and AIs, and theories of consciousness. All this plus our usual look at today's AI headlines. Transcript and URLs referenced at HumanCusp Blog.            

Scientific Sense ® by Gill Eapen: Prof. Kanaka Rajan is Associate Professor of Neurobiology at Harvard Medical School, and a founding faculty member of the Kempner Institute for the Study of Natural and Artificial Intelligence at Harvard University. Her research seeks to understand how important cognitive functions—such as learning, remembering, and deciding—emerge from the cooperative activity of multi-scale neural processes. Please subscribe to this channel:https://www.youtube.com/c/ScientificSense?sub_confirmation=1

Dr. Chris Masterjohn is the host of the Mastering Nutrition Podcast and founder of Mitome, where he helps people optimize their mitochondrial health through advanced analysis. He received his PhD in Nutritional Sciences from the University of Connecticut, completed his postdoctoral research at the University of Illinois, and served as Assistant Professor at Brooklyn College before choosing to work independently - free from institutional constraints - in science research and education. His groundbreaking SSRI series on his substack hasn't just exposed the truth about these drugs. It's revealed that we've been looking at them completely wrong. Dr. McFillin and Dr. Masterjohn expose how these drugs act as mitochondrial toxins, disrupt cellular energy, and deplete serotonin. They also explore the consequences no one talks about: from prenatal exposure to why so many patients say they feel “dead inside.”Chris Masterjohn, PhD Website Dr. Roger McFillin / Radically Genuine WebsiteYouTube @RadicallyGenuineDr. Roger McFillin (@DrMcFillin) / XSubstack | Radically Genuine | Dr. Roger McFillinInstagram @radicallygenuineContact Radically GenuineConscious Clinician CollectivePLEASE SUPPORT OUR PARTNERS15% Off Pure Spectrum CBD (Code: RadicallyGenuine)10% off Lovetuner click here

In this episode Fred interviews Dr. Shaleen Kendrick, the creator of the cutting-edge Neuro-Relational Leadership™ model, which merges neuroscientific understanding with Enneagram wisdom to create cultures where humans can grow, thrive, and evolve. Shaleen's aim is to contribute to humanity's forward momentum by helping the integration of humanity's three intelligence centers—mental (mind), instinctual (body), and emotional (spirit)—in unique ways and with interdisciplinary insights. This interdisciplinary model can be practically applied across various contexts to create growth and emergent abilities in individuals, organizations, and societal systems. NRL™ creates dynamic balance, adaptive functioning, and new emergent ability. https://www.shaleenkendrick.com/ https://www.nrintegration.com/  

BUFFALO, NY — August 26, 2025 — A new #research paper was #published in Volume 17, Issue 7 of Aging (Aging-US) on July 21, 2025, titled “Association of DNA methylation age acceleration with digital clock drawing test performance: the Framingham Heart Study.” In this study, led by first author Zexu Li from the Department of Anatomy and Neurobiology at Boston University Chobanian and Avedisian School of Medicine, and corresponding author Chunyu Liu from Boston University Chobanian and Avedisian School of Medicine and Boston University School of Public Health, researchers found that individuals with signs of faster biological aging had lower scores on a digital cognitive test taken seven years later. The findings suggest that the rate at which a person ages at the molecular level may be associated with how well their brain functions as they grow older. Using data from the Framingham Heart Study, the researchers examined the relationship between biological aging and cognitive health. They used DNA methylation (DNAm) patterns—chemical changes that occur in the DNA with aging, known as epigenetic aging—to estimate biological age acceleration, and used the digital Clock Drawing Test (dCDT) to assess cognitive performance. The dCDT is a computerized version of a traditional pen-and-paper test that evaluates memory, thinking speed, and motor control. It provides an overall score and measures performance in specific areas such as spatial reasoning and movement. Among 1,789 participants, higher levels of epigenetic age acceleration were associated with significantly lower cognitive scores, particularly those over age 65. Of all the epigenetic aging markers examined, the DunedinPACE measure showed the strongest association with reduced brain function in both younger and older adults. Other measures, such as Horvath and PhenoAge, were associated with lower scores only in older adults. Key areas affected included motor skills and spatial reasoning. The researchers also studied blood-based protein markers used in an aging measure called GrimAge. Two proteins, PAI1 and ADM, were closely associated with lower cognitive scores, especially in older individuals. These results suggest that declines in brain and motor functions may reflect broader aging-related changes throughout the body. “Digital cognitive measures displayed stronger associations with most DNAm aging metrics among older compared to younger participants, likely to reflect the cumulative and nonlinear age influences on both brain health and DNAm.” This study supports the idea that epigenetic age may be a more accurate predictor of cognitive decline than chronological age. The dCDT, which is easy to use, automated, and more precise than traditional tools, may help detect early signs of brain aging. When combined with DNAm measures, it could become a valuable part of regular health screenings. Overall, the findings provide strong evidence that faster biological aging is associated with cognitive decline. This research may lead to better ways of identifying and monitoring brain health in aging populations. DOI - https://doi.org/10.18632/aging.206285 Corresponding author - Chunyu Liu - liuc@bu.edu Video short - https://www.youtube.com/watch?v=4hyjDqnPs8w Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts To learn more about the journal, please visit our website at https://www.Aging-US.com​​ and connect with us on social media at: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Bluesky - https://bsky.app/profile/aging-us.bsky.social Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Sich viele Gedanken über etwas machen, das kennt Nele. Sie neigt zum Overthinking. Was Ursachen für das übermäßige Nachdenken sind und wie wir das Gedankenkarussell wieder verlassen können, erklären zwei Expertinnen. (Wiederholung vom 7. Mai 2025)**********Ihr hört: Gesprächspartnerin: Nele, grübelt vor und nach sozialen Situationen Gesprächspartnerin: Julia Funk, Psychologin, Wissenschaftliche Mitarbeiterin an der Ludwig-Maximilians-Universität München, hat zu repititivem negativen Denken promoviert Gesprächspartnerin: Birgit Derntl, Professorin für psychische Gesundheit und Gehirnfunktion von Frauen, Universitätsklinik für Psychiatrie und Psychotherapie am Universitätsklinikum Tübingen Autor und Host: Przemek Żuk Redaktion: Friederike Seeger, Stefan Krombach, Lena Mempel, Lara Lorenz Produktion: Susanne Beyer**********Quellen:Funk, J. (2025): Repetitive negative thinking in adolescents and young adults: key features, etiological factors and psychological interventions. Dissertation, LMU München: Fakultät für Psychologie und Pädagogik.Hilmer, H. (2021). Mit Grübeln umgehen. In: Konflikte in Projekten. Springer Gabler, Berlin, Heidelberg.Rosenbaum, D. et al. (2021). Insights from a laboratory and naturalistic investigation on stress, rumination and frontal brain functioning in MDD: An fNIRS study. Neurobiology of Stress 15, Nov. 2021.**********Mehr zum Thema bei Deutschlandfunk Nova:Overthinking: Wenn wir unsicher sind, wie wir rüberkommenPsychologie: Woran wir denken, wenn wir "nichts Besonderes" denkenStille und Lärm: Achtsam mit unseren Gedanken umgehen lernen**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .**********Meldet euch!Ihr könnt das Team von Facts & Feelings über Whatsapp erreichen.Uns interessiert: Was beschäftigt euch? Habt ihr ein Thema, über das wir unbedingt in der Sendung und im Podcast sprechen sollen?Schickt uns eine Sprachnachricht oder schreibt uns per 0160-91360852 oder an factsundfeelings@deutschlandradio.de.Wichtig: Wenn ihr diese Nummer speichert und uns eine Nachricht schickt, akzeptiert ihr unsere Regeln zum Datenschutz und bei Whatsapp die Datenschutzrichtlinien von Whatsapp.

TWiN discusses research showing that Lactobacillus acidophilus promotes cognitive function recovery after cerebral ischemia, by regulating microglial peroxisomal function. Hosts: Vincent Racaniello, Vivianne Morrison, and Tim Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode MicrobeTV Discord Server Arc is pdb molecule of the month (PDB) Probiotics after stroke (Cell Host Microbe) Timestamps by Jolene Ramsey. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv

While we're on summer break, we're bringing back some of the most impactful episodes that deserve a second listen—and this one is just too good to pass up. This is our last re-release for the summer. We will be back with new episodes on September 9th, so be sure to tune back in. In this episode, we're going deep into the neurobiology of eating disorders with Dr. Jeffrey DeSarbo, a renowned psychiatrist and medical director of ED-180, one of the largest private eating disorder treatment centers in the U.S. If you've ever wondered why eating disorder recovery can feel so hard, or what's really going on in the brain beneath the behaviors, this episode will open your eyes and deepen your understanding. Dr. DeSarbo explains the science in a way that's relatable, clear, and deeply compassionate. From the neurological impacts of restriction, binging, and purging to the effects of compulsive exercise and body image distress, we're unpacking it all. This conversation is a must-listen for clinicians, individuals in recovery, and anyone curious about the “why” behind the “what.” In this episode, we're talking about: Dr. Jeffrey De Sarbo's unique path from finance to psychiatry, and how he became a leading expert in eating disorder neurobiology. Why eating disorders are “half medical, half psychiatric”—and how this complexity makes them uniquely challenging and important to understand. What neurobiology really means, and how our brains function through electrochemical energy. The role of genetics and epigenetics in eating disorders, and why some people are more biologically predisposed than others. How brain scans show measurable differences in individuals with eating disorders, especially in how different regions of the brain communicate. Why “just eat” or “just stop” is a myth, and how deeply biological factors resist simplistic solutions. How behaviors like binging can physically change the brain, creating patterns that mimic addiction and drive compulsion. What restriction does to the brain, including loss of gray and white matter and cognitive impairment, even when someone appears high-functioning. The dangerous effects of purging, from electrolyte imbalances to cardiac issues, and why “feeling fine” doesn't mean you're medically safe. The neurobiology of compulsive exercise, and how stress hormones and overtraining harm the brain's ability to function and recover. Why body image distress is not just emotional but neurological, with altered blood flow patterns and measurable differences in perception. How neurobiology informs the recovery process, and why rewiring the brain is both essential and entirely possible—with time, persistence, and support. Tweetable Quotes "Eating disorders are not a choice. It's something that happens." - Dr. DeSarbo "Oftentimes, when we work with our eating disorder patients, they have 10,000 plus hours of eating disorder thought processes—so they become experts." - Dr. DeSarbo "Restriction with anorexia nervosa is giving you a compromised brain." - Dr. DeSarbo "You're invincible until you are not—and then it is too late." - Rachelle Heinemann "What percentage of your free thoughts, when you're not busy actively doing something, do you spend thinking about or worrying about food, weight, body image, calories, exercise?" - Dr. DeSarbo Resources ED180  The Brain and Neurobiology of Eating Disorders Translating ED Nora Volkaw Grab my Journal Prompts Here! Looking for a speaker for an upcoming event? Let's chat! Accepting new clients in July - Find out if we're a good fit!   LEAVE A REVIEW + help someone who may need this podcast by sharing this episode. Be sure to sign up for my weekly newsletter here! You can connect with me on Instagram @rachelleheinemann, through my website www.rachelleheinemann.com, or email me directly at rachelle@rachelleheinemann.com

This episode is brought to you by Alma. Visit HelloAlma.com/ATPP to learn more Get the Couples Therapy 101 course: https://www.couplestherapistcouch.com/ Join the Couples Therapist Inner Circle: https://www.couplestherapistcouch.com/inner-circle-new Join The Couples Therapist Couch Facebook Group: https://www.facebook.com/groups/295562197518469/ In this episode, Shane talks with Dr. Dan Siegel about brain science & attachment. Dan is the Clinical Professor of Psychiatry at the UCLA School of Medicine, Executive Director of the Mindsight Institute, and Author of numerous books & articles on mindfulness & neurobiology. Hear how interpersonal neurobiology applies to couples therapy, why our brain plays such a big part in our relationships, how much attachment influences the present, the benefits of mindfulness, and how to work on the emotional health of your clients. To learn more about Dr. Dan Siegel, his courses, and his books, visit: DrDanSiegel.com MindsightInstitute.com  

Smiling is a universal way to show happiness. But not all smiles are happy. In reality, we smile less for happiness than for social reasons that have nothing to do with happiness. That said, few things are more ingratiating and calming as another person's genuinely warm smile. But, maybe it's because a genuine smile is such a great thing that we're always looking for the false one. But we shouldn't assume that a smile that reflects something other than unadulterated joy is always a bad thing. Smiling has an evolutionary function, helping to ensure our survival after birth. Babies first smile while still in the womb and deliberately smile at us shortly thereafter less because they're thrilled to have us as parents and more to keep us happy with them. There's a reason for this. Smiling has high social benefits: those who smile are considered more social, more accessible, more helpful, and more attractive. But, what happens when you can't smile? The absence of a smile is life-changing, yet until we lose it, we take it for granted. There are many illnesses that make it difficult to smile including Parkinson's Disease, Bell's Palsy, and Moebius Syndrome, a particularly devastating illness that afflicts babies. Today, we talk to Jonathan Kalb, a professor of Theatre at Hunter College who spent three years recovering his smile after developing what he thought was a temporary bout of Bell's Palsy. He wrote this thoughtful essay on his experience for The New Yorker. Beyond the inability to smile, what happens you just don't want to smile? The social customs for smiling vary between countries, with many countries feeling we Americans simply smile too much. Partly, it depends on whether you're a woman. As a result, women may smile more, even when they don't want to. GUESTS: Jonathan Kalb: Professor of Theatre at Hunter College CUNY and the author of multiple books on theatre Marianne LaFrance: Professor of Psychology and Women’s Gender and Sexuality Studies at Yale University and the author of Why Smile: The Science Behind Facial Expressions Margaret Livingstone: Professor of Neurobiology at Harvard University, and author of Vision and Art: The Biology of Seeing The Colin McEnroe Show is available as a podcast on Apple Podcasts, Spotify, Amazon Music, TuneIn, Listen Notes, or wherever you get your podcasts. Subscribe and never miss an episode! Subscribe to The Noseletter, an email compendium of merriment, secrets, and ancient wisdom brought to you by The Colin McEnroe Show. Colin McEnroe and Chion Wolf contributed to this show, which originally aired on March 31, 2015.Support the show: http://www.wnpr.org/donateSee omnystudio.com/listener for privacy information.

Retired Detective Justin Boardman spent 15 years in law enforcement with Utah's West Valley City Police Department, including seven years in the Special Victim's Unit. During that time, he conducted nearly 300 forensic interviews with child victims and 140 interviews with adult sexual assault survivors. Justin co-authored a groundbreaking Trauma-Informed Victim Interview Protocol (with Donna Kelly) that integrates the Neurobiology of Trauma into investigations—leading to improved prosecutions and critical culture change in law enforcement. In this conversation, Justin shares: How trauma affects memory and disclosure Why traditional investigative approaches often fail survivors The role of empathy and understanding in law enforcement His mission to push for victim-centered, suspect-focused, trauma-informed investigations Learn more about Justin and his trainings at justinboardman.com. ✨ Ready to live more authentically—in your emotions, your energy, and your relationships? Book a session with our expert practitioners at radiatewellnesscommunity.com/appointment.

Boost well-being and retention for child welfare workers through trauma-informed care and psychological safety.In this episode of the Academy i3 podcast, the discussion centers around the critical issues of workforce recruitment and retention in the field of child welfare. Guest Lisa Maaca Bartlett, an experienced social work professional and academic, shares her insights on creating supportive work environments, the impacts of trauma-informed care, and the significance of psychological safety within organizations. She emphasizes the importance of understanding the unique challenges faced by child welfare workers, including secondary traumatic stress, and offers practical strategies to improve retention and well-being among staff. This episode is a valuable resource for leaders and practitioners looking to enhance their organizational culture and support their teams effectively.Episode Chapters:00:00 - Intro07:00 – Research on Workforce Retention11:47 – Themes for High Turnover Rates16:38 – Impact of Stress and Burnout24:22 – Trauma-Informed Care in Practice35:29 – Supporting Current Workers: Psychological Safety36:20 – Understanding Psychological Safety37:30 – Four Stages of Psychological Safety48:42 – Trauma-Informed Care and Workforce Retention StrategiesCheck out the resources we mentioned:National Child Traumatic Stress Network (NCTSN) – Trauma-Informed Care Curriculum: https://www.nctsn.org/Harvard Business Review Article: "The Hazards of a ‘Nice' Company Culture" by Timothy R. Clark (2021): https://hbr.org/2021/06/the-hazards-of-a-nice-company-cultureLearn about our guest: Lisa Maaca Bartlette, MSSA, is a social service entrepreneur and founder of Lisa Maaca, Inc., specializing in Trauma-Informed Care. Drawing from her own healing journey and extensive social work experience in Ohio and California, Lisa delivers transformative, evidence-based programs and keynotes across the US. She consults and trains California's Child Welfare and Juvenile Probation workforce, helping reshape how trauma is understood and addressed. With a background in Business Management, a Master of Science in Social Administration, and ongoing doctoral studies focused on Trauma-Informed Care and Neurobiology of Trauma, Lisa combines research and real-world practice to inspire positive organizational change.Contact Lisa on LinkedIn: https://www.linkedin.com/in/lisa-maaca-bartlette-47225525/ Subscribe for more psychological safety and workforce development content: https://www.youtube.com/@TheAcademySDSUFollow us on LinkedIn: linkedin.com/company/sdsuacademy#ChildWelfareWorkforce #TraumaInformedLeadership #PsychologicalSafety

In this episode, host Catherine Glass speaks with David Cosio about  the complex and often overlooked relationship between anxiety and chronic pain. They explore the neurobiological underpinnings of both conditions, how they influence each other, and what the future of integrated pain management may look like, from AI to psychedelics and beyond. 

In this series, host Catherine Glass speaks with David Cosio about  the complex and often overlooked relationship between anxiety and chronic pain. They explore the neurobiological underpinnings of both conditions, how they influence each other, and what the future of integrated pain management may look like, from AI to psychedelics and beyond.  0:47 - Acceptance and Commitment Therapy  3:17 - Anxiety and Chronic Pain  5:50 - ‘Let Them' Concept  8:09 - David's Book  10:07 - Book Section Recommendations  11:20 - Lifestyle Factors  12:00 - Grief and Chronic Pain  14:06 - Delayed Reaction to Grief 

This episode is brought to you by Alma. Visit HelloAlma.com/ATPP to learn more Get the Couples Therapy 101 course: https://www.couplestherapistcouch.com/ Join the Couples Therapist Inner Circle: https://www.couplestherapistcouch.com/inner-circle-new Join The Couples Therapist Couch Facebook Group: https://www.facebook.com/groups/295562197518469/ In this episode, Shane talks with Juliane Taylor Shore about boundaries & neurobiology. Juliane is an Educator, Therapist, and Writer inspiring people to shift their relationships with self, others, and the world. She's the Author of “Setting Boundaries That Stick: How Neurobiology Can Help You Rewire Your Brain to Feel Safe, Connected, and Empowered.” Hear how our salience network works, how our emotions & history influence our actions, how to witness yourself doing therapy, why you're a gift to the clients you work with, and how we can work with our brains to learn how to witness our minds. To learn more about Juliane Taylor Shore, her book, and her workshops, visit: JulianeTaylorShore.com JulianeTaylorShore.com/Book   You can also listen to Juliane on Episode 199 of The Couples Therapist Couch  

For today's episode, we will cover B2 (insistence on sameness, inflexible routines, and ritualized behaviors) and B3 (highly restricted, fixated interests with abnormal intensity). It emphasizes the preference for an internal world, where repetition and self-directed learning thrive, contrasting this with societal misunderstandings that label such behaviors as abnormal. The episode critiques societal pressures to conform to broad knowledge expectations, highlighting how Autistics find comfort in their self-driven focus, supported by neurobiological insights like the role of the mesencephalon in attention and environmental interaction.Further, the episode addresses the challenges Autistics face with external disruptions, like unpredictable social interactions or changes to routines, which can feel debilitating due to the brain's predictive nature and metabolic energy demands. The discussion ties these struggles to the medial prefrontal cortex's role in adaptive responses, explaining why Autistics may resist environmental changes to maintain their internal homeostasis. The episode underscores the unique learning style of Autistics, advocating for self-directed interests over externally imposed norms.Daylight Computer Companyuse "autism" for $25 off athttps://buy.daylightcomputer.com/RYAN03139Chroma Iight Devicesuse "autism" for 10% discount athttps://getchroma.co/?ref=autism00:00 Daylight Computer Company, use "autism" for $25 discount02:24 Autism DSM Criteria B, Autism phenotypes, DSM criteria B, restricted repetitive behaviors, focus on B2 and B3, prior episodes (1, 2, 6, 7).04:42 B2: Insistence on Sameness, DSM B2, insistence on sameness, inflexible routines, distress at small changes, rigid thinking05:24 B3: Fixated Interests and Autistic Intelligence, DSM B3, Kenner/Asperger kids, autistic intelligence, societal mislabeling.07:15 Autism and Societal Misunderstandings, Autos (self), societal confusion, discomfort with complexity, Autistics' comfort in self, internal state shifts.09:19 Autistic Learning, Love, & Internal World, Autistic intelligence, learning, repetition, professing, self-directed learning, societal pressure.11:40 Path, Meaning, & Love; “Daimon”14:42 Neurobiology and Environmental Interaction, Mesencephalon (midbrain), motor movement, sensory integration, attention bias, lack of environmental orientation, social implications, embryogenesis, Autistic resistance to external changes.17:34 Chroma Light Devices, use "autism" for 10% discount20:43 Routines, Social Challenges, and Adaptive Responses, B2 routines, external insults, brain as prediction machine, metabolic energy, social interactions, Autistic efficiency, frustration with unpredictability, medial prefrontal cortex, adaptive responses25:21 Reviews/Ratings & Contact InfoX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

In this series, host Catherine Glass speaks with David Cosio about  the complex and often overlooked relationship between anxiety and chronic pain. They explore the neurobiological underpinnings of both conditions, how they influence each other, and what the future of integrated pain management may look like, from AI to psychedelics and beyond. 

In this series, host Catherine Glass speaks with David Cosio about  the complex and often overlooked relationship between anxiety and chronic pain. They explore the neurobiological underpinnings of both conditions, how they influence each other, and what the future of integrated pain management may look like, from AI to psychedelics and beyond.  Timestamps: 1:07 - Background  2:10 - Day to Day  3:21 - Why Pain Management  6:06 - Conversations About Pain  7:54 - Key Neurobiological Mechanisms  9:50 - Genetics  11:02 - Brain Mechanisms  11:32 - Biomarkers 

Ruminations and reassurances. Checking and counting. Suffering and stigmas. It's OCD, babes! OCD is now considered one of the most common psychiatric conditions, afflicting 2% to 3% of the general population, and this episode is among our top-requested topics. So we snagged a top-shelf ologist: psychiatrist, researcher, advocate and OCD Neurobiologist, *the* Dr. Wayne Goodman. We cover myths, misconceptions, diagnosis and treatment options for OCD, as well as advice for loved ones. Also: PANDAS, famous folks who are helping break the silence on it, intrusive thoughts, deep brain stimulation, genetic components, links to Tourette's Syndrome, finding the right doctor, and the behavioral therapy that is the gold standard for OCD. And surprise! Later this week we'll have a bonus episode on OCD lived experience with neuroscientist, mental health advocate and OCD-haver, Uma Chatterjee. View Dr. Goodman's publications on ResearchGate and follow him on Google ScholarA donation went to International OCD FoundationMore episode sources and linksSmologies (short, classroom-safe) episodesOther episodes you may enjoy: Attention-Deficit Neuropsychology (ADHD), Molecular Neurobiology (BRAIN CHEMICALS), Volitional Psychology (PROCRASTINATION), Suicidology (SUICIDE PREVENTION & AWARENESS), Post-Viral Epidemiology (LONG COVID), Disability Sociology (DISABILITY PRIDE), Gustology (TASTE), Oikology (DECLUTTERING)Sponsors of OlogiesTranscripts and bleeped episodesBecome a patron of Ologies for as little as a buck a monthOlogiesMerch.com has hats, shirts, hoodies, totes!Follow Ologies on Instagram and BlueskyFollow Alie Ward on Instagram and TikTokEditing by Mercedes Maitland of Maitland Audio Productions and Jake ChaffeeManaging Director: Susan HaleScheduling Producer: Noel DilworthTranscripts by Aveline Malek Website by Kelly R. DwyerTheme song by Nick Thorburn

TWiN explains research which identifies the regions of the brain that register a long-lasting aversion to potentially poisonous food even with meal to illness delays of several days. Hosts: Vincent Racaniello, and Tim Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode MicrobeTV Discord Server A neural mechanism for post-ingestion feedback (Nature) Timestamps by Jolene Ramsey. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv

Send us a textHow brain synapses work and fuel themselves with fat.Episode Summary: Dr. Timothy Ryan talks about the high energy costs of synapses, the role of mitochondria and glycolysis, and challenge the long-held view that the brain relies solely on glucose by discussing new evidence that neurons burn fats from lipid droplets for fuel, especially during activity. The talk touches on metabolic flexibility, links to epilepsy treatments like ketogenic diets, neurodegenerative diseases, and future research on brain energy sources.About the guest: Timothy Ryan, PhD is a professor of biochemistry at Cornell University. His research focuses on the molecular mechanisms of synaptic transmission, particularly vesicle recycling and the bioenergetics that power neural communication. Discussion Points:Synapses are tiny structures with ~100 vesicles per site (on average), converting electrical signals to chemical ones.Brain tissue is energy-hungry due to trillions of synapses (in humans), relying on local mitochondria (present in only ~half of synapses) and glycolysis.Vesicles use proton pumps and transporters to concentrate neurotransmitters, requiring ATP to maintain gradients.Neurons are metabolically fragile; cutting fuel supply quickly impairs synapses.Dogma held brains don't burn fats, but new work shows neurons form lipid droplets (fat stores) that are invisible because constantly used for energy via beta-oxidation.Silencing neurons builds lipid droplets like resting muscle; activity speeds their breakdown, indicating demand-driven fat use.Inhibiting neuron-specific fat-processing enzymes accumulates droplets and induces torpor (hibernation-like state) in animals, signaling metabolic stress.Ketogenic diets aid epilepsy by shifting to ketones; fats may explain this, with potential ties to aging and neurodegeneration like Alzheimer's.Brain may be a "hybrid" fuel user (glucose + fats), with open questions on fat sources and roles in cognition or disease protection.Related episode:M&M 158: Ketosis & Ketogenic Diet: Brain & Mental Health, Metabolism, Diet & Exercise, Cancer, Diabetes | Dominic D'Agostino*Not medical advice.Support the showAll episodes, show notes, transcripts, and more at the M&M Substack Affiliates: KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off Readwise: Organize and share what you read. 60 days FREE through link SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts

Bonnie Buckner, PhD, is the founder and CEO of the International Institute for Dreaming and Imagery, where she teaches people how to use dreaming and imagery for personal growth, problem-solving, and enhanced creativity. Buckner has used dreamwork as the basis for her work as an executive and creative coach for over twenty years. In addition she continues to serve as an Executive Coach and Senior Fellow at George Washington University's Center for Excellence in Public Leadership and Co-Faculty Director of their eCo Leadership Coaching certification program. Discover your dreams, find your purpose, and decode your subconscious. In The Secret Mind, creative dreamwork expert Dr. Bonnie Buckner teaches you how to use your nighttime dreams as a practical tool for not only solving your challenges, but also developing your fullest potentials and living a life of purpose. Harnessing the power of dreams has been Buckner's life's work, and what she has found in doing dreamwork with executives and creatives across the globe is this: We all have a "secret mind"—the part of our brain that has all the tools we need to solve our own problems—and that "secret mind" can be accessed through your dreams. In The Secret Mind, Buckner shares her method for translating the mystery of dreams so that you have access to your own inner powerhouse for transformation. You will learn how to:—strengthen the muscle for remembering and understanding your dreams—identify patterns and unresolved issues in dreams—use the waking dream method to re-enter dreams to address unfinished business in your waking life Drawing from neurobiology and social psychology, The Secret Mind presents dreaming as a practice for both personal and global development. With Buckner's simple tools and exercises, a more beautiful, creative world is just a dream away.

Rejection Sensitivity Dysphoria (RSD) isn't about being overly sensitive. It's about a nervous system that experiences rejection as danger. In this episode, I explore RSD through the lens of relational neuroscience, attachment, memory, and regulation. Whether you see this in yourself or your child, this episode will help you understand why rejection feels so big, and what actually helps.In this episode, you'll learn:Why RSD reactions are so intense and how they're rooted in memory and nervous system statesHow attachment experiences shape our sensitivity to rejectionWhat actually helps when RSD shows up (for you or your child), including co-regulation and self-compassionResources mentioned in this podcast:Trauma, Memory, & Behavior: Part 1 {EP 90}The Neurobiology of Toxic Shame {EP 119}1% Better Is Enough. {EP 166}All Behavior Makes Sense {EP 198}Read the full transcript at:RobynGobbel.com/rejectivesensitivityProfessionals who work with parents of kids with big, baffling behaviors!Join us for Reframing Resistance: Supporting Parents and Caregivers thru the Lens of Relational Neuroscience.See the website for all details and to register!RobynGobbel.com/ReframingResistance Check Out All Robyn's Free Resources!You can download all sorts of free resources, including webinars, eBook, and infographics about topics such as lying, boundaries, and co-regulation!RobynGobbel.com/FreeResources :::Grab a copy of my book Raising Kids with Big, Baffling Behaviors robyngobbel.com/bookJoin us in The Club for more support! robyngobbel.com/TheClubApply for the Baffling Behavior Training Institute's Professional Immersion Program (formerly Being With) robyngobbel.com/ImmersionFollow Me On:FacebookInstagram Over on my website you can find:Webinar and eBook on Focus on the Nervous System to Change Behavior (FREE)eBook on The Brilliance of Attachment (FREE)LOTS & LOTS of FREE ResourcesOngoing support, connection, and co-regulation for struggling parents: The ClubYear-Long Immersive & Holistic Training Program for Parenting Professionals: The Baffling Behavior Training Institute's (BBTI) Professional Immersion Program (formerly Being With)

In today's episode I am joined by Yale neuroscientist Dr. Dylan Gee for a fascinating look at what's actually happening in our children's brains when we offer support, warmth, and connection. We delve into the neurobiology and neurobiological mechanisms that underpin parent-child interactions, particularly focusing on emotional development. We also dive into the individual differences in children's needs, the concept of 'safety signals,' and the balance between parental support and fostering independence.I WROTE MY FIRST BOOK! Order your copy of The Five Principles of Parenting: Your Essential Guide to Raising Good Humans Here: https://bit.ly/3rMLMsLSubscribe to my free newsletter for parenting tips delivered straight to your inbox: draliza.substack.com Follow me on Instagram for more:@raisinggoodhumanspodcast Sponsors:Wayfair: Shop outdoor furniture, grills, lawn games, and WAY more for WAY less. Head to Wayfair.com right now to explore a HUGE outdoor selection. Quince: Give your summer closet an upgrade—with Quince. Go to Quince.com/humans for free shipping on your order and three hundred and sixty-five -day returns. TWaterWipes: Visit WaterWipes.com to learn more about how WaterWipes effectively cleans with minimal ingredients that leave nothing behind.ResortPass: Visit resortpass.com/humans and use code humans at checkout for $20 off your first purchase.Bobbie: Bobbie is offering an additional 10% off on your purchase with the code:humans. Visit www.hibobbie.com to find the Bobbie formula that fits your journey.Visit LiveConscious.com today and use code HUMANS at checkout.Please note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.Produced by Dear Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

“Sleep is intrinsic to every aspect of our waking life.” (Dr Guy Leschziner)In this episode of The Evolving Leader, co-hosts Jean Gomes and Emma Sinclair delve into the biological roots of our most human behaviours with Professor Guy Leschziner, neurologist and author of The Seven Deadly Sins: The Biology of Being Human. From the neuroscience behind gluttony, anger and pride to the unpredictable nature of envy and the myth of free will, Guy offers a powerful reframing of how biology shapes leadership, judgement, and motivation. He also shares essential sleep research and practical guidance that every leader should hear, particularly those running on too little rest and too much pressure.Whether you're leading through complexity or seeking to better understand the hidden forces that shape your thinking and responses, this conversation offers insight into how our brains construct reality and how leaders can respond with greater empathy, adaptability and presence. #Leadership #Neuroscience #GuyLeschziner #EvolvingLeader #SleepScience #CognitiveDiversity #AdaptiveLeadership #SevenDeadlySins #ExecutiveWellbeing #FreeWill #Motivation #Neurobiology #Empathy #DecisionMakingSend a message to The Evolving Leader team

In this explosive and highly anticipated episode, Dr. Roger McFillin hosts Dr. Ragy Girgis, a Columbia University Professor of Psychiatry and researcher, for a no-holds-barred confrontation that exposes the shocking divisions tearing apart the mental health field. What begins as a conversation about mass violence research rapidly explodes into a devastating examination of psychiatric medicine's crumbling foundations, questionable effectiveness, and devastating potential harms. The two clash in fierce, unrelenting disagreements over fundamental issues including the validity of DSM diagnoses, the debunked "chemical imbalance" theory of depression, dangerous SSRI safety cover-ups and black box warnings, corrupted research quality and pharmaceutical industry manipulation, and the catastrophic crisis of psychiatric drug overprescription poisoning 1 in 4-5 Americans. Dr. Girgis desperately defends traditional academic psychiatry and current treatment approaches, while Dr. McFillin ruthlessly dismantles the entire paradigm, arguing that the current system is systematically creating chronic mental illness rather than healing it. Buckle up for this brutal intellectual warfare.___________________________________________________________________________________________________________________________________________________Throughout the interview, Dr. Girgis repeatedly stated that "the data is clear" while dismissing contradictory evidence that challenges his conclusions. For our listeners' benefit, I have compiled research and documentation that directly disputes several of Dr. Girgis's key claims.Serotonin Hypothesis of Depression1. The serotonin theory of depression: a systematic umbrella review of the evidence (Moncrieff et al.)Conclusions: "This review suggests that the huge research effort based on the serotonin hypothesis has NOT produced convincing evidence of a biochemical basis to depression. This is consistent with research on many other biological markers . We suggest it is time to acknowledge that the serotonin theory of depression is NOT empirically substantiated."2.What has serotonin to do with depression?Conclusions: "Simple biochemical theories that link low levels of serotonin with depressed mood are no longer tenable."3. Is the chemical imbalance an ‘urban legend'? An exploration of the status of the serotonin theory of depression in the scientific literatureViolence & Suicide Associated with SSRI's 1. Precursors to suicidality and violence on antidepressants: systematic review of trials in adult healthy volunteers2. Prescription Drugs Associated with Reports of Violence Towards Others3. Antidepressant-induced akathisia-related homicides associated with diminishing mutations in metabolizing genes of the CYP450 family4. Lexapro Approved for Pediatric Use Despite the 6-Fold Increase in Suicide Risk5. McFillin Substack Review on Lexapro approved despite Suicide Risk6. Suicidality and aggression during antidepressant treatment: systematic review and meta-analyses based on clinical study reports7. Antidepressants Increase Suicide Attempts in Youth; No Preventative Effect8. Effect of selective serotonin reuptake inhibitor treatment following diagnosis of depression on suicidal behaviour risk:9.  FDA Warning: Antidepressants increase the risk of suicidal thinking and behavior (suicidality) in children and adolescents10.  Suicide Mortality in the United States, 2001–2021 CDC documentation11. US suicide rate reaches highest point in more than 80 years: See what latest data shows12.  CNN article reporting Eli Lilly Internal Documents"An internal document purportedly from Eli Lilly and Co. made public Monday appears to show that the drug maker had data more than 15 years ago showing that patients on its antidepressant Prozac were far more likely to attempt suicide and show hostility than were patients on other antidepressants and that the company attempted to minimize public awareness of the side effects. The 1988 document indicated that 3.7 percent of patients attempted suicide while on the blockbuster drug, a rate more than 12 times that cited for any of four other commonly used antidepressants.In addition, the paper said that 1.6 percent of patients reported incidents of hostility -- more than double the rate reported by patients on any of four other commonly used antidepressants."Examples of Violence after Prescription in legal system (Sample)January 24, 2020 – Newcastle, South Dublin, Ireland: Deirdre Morley, 44, smothered and killed her two sons Conor, 9, and Darragh, 7, and her three-year-old daughter Carla McGinley in their family home. She had been taking antidepressants since October 2018 and was admitted to St. Patrick's Mental Health Services on July 6, 2019, but was discharged after a short period, but was put on a combination of two antidepressants and a sedativeMay 11, 2018 – Osmington, Western Australia: Peter Miles, 61, shot his 35-year-old daughter and four grandchildren, aged 8 through 13, while they slept in their beds, in a shed that had been converted to a second house on the property. He then turned the gun on his 58-year-old wife in the living room of their house, before placing a call to police alerting them to his crimes. When they arrived, Miles was also found dead from a gunshot wound. Miles had started taking antidepressant medication just weeks before.April 6, 2018 – Wadsworth, Ohio: Gavon Ramsay, 17, strangled his neighbor, 98-year-old Margaret Douglas in her own home. His parents blame his actions on his having been misprescribed Zoloft. After a report by his school principal that the teen was depressed and might harm himself, he “returned to therapy,” and after a recommendation by a psychologist, the family's pediatrician prescribed the antidepressant Zoloft. From January through March leading up to the incident, the dosages were increased. During this time, his mother said she observed her son's behavior change—becoming increasingly irritable and hostile and saying bizarre things.October 21, 2013 – Sparks, Nevada: 12-year-old Jose Reyes opened fire at Sparks Middle School, killing a teacher and wounding two classmates be...

How can we learn to see more of our expectations and assumptions?...Today, Abbie and Rachel are two 'embodied minds' exploring the neurobiology of sensemaking, including our brains being more prediction than reaction, the controlled illusion of acting out of our expectations, the 'felt sense' we experience that encodes all information about priors, and the perception practice that allows us to check our assumptions. ...Rachel Lilley is an Associate Professor at the Birmingham Leadership Institute, a Systems Thinking and Leadership teaching and research centre at the University of Birmingham, UK.She is a practitioner-researcher in systems approaches and systems leadership and also the Programme Director for an innovative transdisciplinary Master's Programme combining Systems Leadership and Systems Practice. Rachel's high-impact research examines human decision-making, systems thinking capabilities, and behavioural change. It has supported policy design and practice, community initiatives, and leadership development at all levels. She has a particular interest in building capabilities to address climate and social change.Rachel is an expert in human sensemaking, with specialist knowledge in cognition, consciousness, and perception. Her theoretical expertise is supported and informed by a strong track record of practising, teaching, and developing embodied perception skills in teams, organisations, and individuals.She has over 30 years of experience as a systems practitioner working with public and third-sector organisations, as well as large corporates, addressing climate change, social issues, leadership, behaviour change, community engagement, and well-being....Stories Lived. Stories Told. is created, produced & hosted by Abbie VanMeter.Stories Lived. Stories Told. is an initiative of the CMM Institute for Personal and Social Evolution....Music for Stories Lived. Stories Told. is created by Rik Spann....⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Explore all things Stories Lived. Stories Told. here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Explore all things CMM Institute here.

The prevailing scientific view of the fundamental nature of homosexuality has undergone a significant evolution in the last several decades. Where once the scientific and medical establishment maintained an unqualified belief that homosexuality was a form of psychological deviance, today a solid majority of psychiatrists and psychologists themselves believe that biological factors (genes, brain, prenatal chemistry) also play an important role.  Dr. Dean Hamer's research for the first time examined at a molecular level how our sexual identities are rooted in our biology. He has gone on to study the role that biology plays in our faith. In his works and books, Dr. Hamer reveals that inclination toward religious faith is in part due to our genes and may even offer an evolutionary advantage by reducing stress, preventing disease, and extending life. We will discuss these and other works that bring in the role of culture, such as transgender identities in Polynesia. Dean Hamer is an American geneticist, author, and filmmaker and the among the first scientists to demonstrate a linkage between genes and sexual orientation. He is known for his research on the role of genetics in sexual orientation and for a series of popular books and films that have changed scientific and public understandings of human sexuality and gender. He was the chief of the Gene Structure and Regulation Section at the U.S. National Cancer Institute; upon retirement in 2011 he was designated scientist emeritus. Hamer has won numerous awards, including the Trinity College Thompson History Prize, Maryland Distinguished Young Scientist Award, Ariens Kappers Award for Neurobiology, New York Times book-of-the year author, and an Emmy Award. An Asia-Pacific Affairs Member-led Forum program. Forums and chapters at the Club are organized and run by volunteer programmers who are members of The Commonwealth Club, and they cover a diverse range of topics. Learn more about our Forums. OrganizerKalidip Choudhury  Learn more about your ad choices. Visit megaphone.fm/adchoices

TWiN reveals that proteins travel from the blood to the brain where they are taken up by microglia, revealing a new mode of communication between the brain and the periphery. Hosts: Vincent Racaniello, Tim Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode MicrobeTV Discord Server Circulatory proteins taken up by brain microglia (bioRxiv) Timestamps by Jolene Ramsey. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv

I was happy to connect with Dr. Louann Brizendine today! She is the founder of the Women's Mood and Hormone Clinic at UCSF. She completed her degree in Neurobiology at the University of California, Berkeley, graduated from Yale School of Medicine, and completed her internship and residency at Harvard Medical School. She also served on the faculty of Harvard University and the University of California, San Francisco. Dr. Brizendine founded the Women's Mood and Hormone Clinic at UCSF. Her New York Times bestseller, The Female Brain, and its follow-up, The Male Brain, continue to be read worldwide.  Today, we dive deeply into her new book, The Upgrade: How the Female Brain Gets Stronger and Better in Midlife and Beyond, which was released in April 2022. IN THIS EPISODE YOU WILL LEARN: The transition and the upgrade stage of life explained Celebrating the transitional time of life and not fearing it How hormones help guide behavior Transition Stages 1,2,3 and what they mean Then onward to the 3 stages of "The Upgrade" Estrogen fluctuations that affect sleep Be aware of caffeine in your food and drinks and how it may affect your sleep. If you are having a problem staying asleep, you may want to cut back on alcohol or drink it earlier in the day. The Women's Health Initiative - (almost 20 years ago) disastrous misinterpretations and negative implications it caused by instilling fear in women to not use Estrogen - including osteoporosis, brain fog, anxiety, and sleep disruptions Hormone Replacement Therapy - now viewed as a positive and much-needed step in women's health Women between the ages of 40-50 should get a bone density scan as one of the determining factors of whether or not to begin hormone replacement therapy. Dr. Brizendine suggests that women should not be fearful of using therapies today to help balance hormones. Cynthia discusses the loss of cognition later in life as another correlative symptom of not receiving needed hormones. Dr. Brizendine advocates doing your own research regarding HRT and not depending only on information from major pharmaceutical companies. Cynthia and Dr. Brizendine discuss the importance of keeping an open mind when it comes to synthetic hormones because of the good they can do. If you are not well and do not feel like you can go on, please, immediately, seek out a doctor who can prescribe medications or hormones to help your particular and unique situation. Be your best and do not suffer in silence any longer. Cynthia says the transitional time of life should and can be a very good time in your life. Consider reading Dr. Brizendine's book(s) to learn more and to keep it as a valuable resource.  Connect with Cynthia Thurlow Follow on X, ⁠Instagram⁠ & ⁠LinkedIn⁠ Check out Cynthia's ⁠website⁠  Connect with Dr. Brizendine ⁠Website⁠ ⁠Facebook⁠ ⁠Instagram⁠ ⁠LinkedIn⁠ ⁠TikTok⁠ Dr. Louann Brizendine's Books ⁠The Upgrade⁠ (newest book) ⁠The Female Brain⁠ ⁠The Male Brain⁠ Resource Mentioned ⁠NAMS - North American Menopause Website

Up to 80% of people may be living with insufficient levels of vitamin D, magnesium, and omega-3 fatty acids—three essential nutrients involved in critical functions like immune defense, cardiovascular health, mood regulation, and brain function. Modern lifestyles—marked by nutrient-poor diets, low sun exposure, chronic stress, and overuse of medications—disrupt the body's ability to absorb and maintain these key nutrients. Deficiencies often go undiagnosed due to outdated testing, yet they're strongly linked to conditions like depression, fatigue, diabetes, and heart disease. In this episode, I talk about, along with Andrew Huberman, how modern lifestyles and diets lead to widespread nutrient deficiencies and chronic disease—and how targeted nutrition and lifestyle changes can restore optimal health. Dr. Andrew Huberman is a neuroscientist and tenured Professor in the Department of Neurobiology at the Stanford University School of Medicine. He has made numerous important contributions to the fields of brain development, brain function, and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills, and cognitive functioning. Dr. Huberman is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award in 2017, which is given to the scientist making the largest discoveries in the study of vision. His lab's most recent work focuses on the influence of vision and respiration on human performance and brain states such as fear and courage. Work from the Huberman Laboratory at Stanford University School of Medicine has been published in top journals including Nature, Science, and Cell and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: Do you need to take Vitamin D? How Magnesium Deficiency Impacts Your HealthHow to Rewire Your Brain For Sleep