eanCast: Weekly Neurology

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eanCast: Weekly Neurology is your source for education, research and updates from the European Academy of Neurology. Regardless of experience level, you are invited to join expert moderators and guests in reviewing, discussing, and debating various topics within the 29 EAN sub-specialties. New neurological topics every month, and new episodes every Monday.

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    • May 4, 2025 LATEST EPISODE
    • weekly NEW EPISODES
    • 22m AVG DURATION
    • 146 EPISODES


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    Latest episodes from eanCast: Weekly Neurology

    Ep. 146: Importance of brain donation in neurodegenerative diseases

    Play Episode Listen Later May 4, 2025 27:59


    Ean Moderator: Yıldız Değirmenci (Istanbul, Türkiye)Guest: Didem Öz (Izmir,  Türkiye)In this episode, Değirmenci and Öz discuss the vital importance of brain donation in understanding and treating neurodegenerative diseases. They also highlight the Turquoise Outreach Project—a meaningful initiative that builds bridges between the community and dementia research, promoting awareness, inclusion, and progress.eanCampus access for Associate Members: If you are a member of a National Neurological Society in Europe, you are most likely already an Associate Member of the EAN and have an account for the eanCampus. If you have provided your email address to your National Neurological Society, it should already be in our database. Here is how you can access the eanCampus as an Associate Member:1. Enter the eanCampus2. Click on the Log In Button3. Log in with your MyEAN credentials and make use of the ‘forgot password'-functionality if necessaryIf you have trouble logging in, please get in contact with our Membership department (membership@ean.org) to cross-check if you are listed as an Associate Member to get access to eanCampus.

    Ep. 145: Why Should Neurologists Care About the World Dance Day?

    Play Episode Listen Later Apr 27, 2025 20:02


    Moderator: Alicia Gonzalez Martinez (Madrid, Spain)Guests: Thomas Berger (Vienna, Austria), Julia Polai (Innsbruck, Austria)In this episode for World Dance Day, Gonzales Martinez discusses the physical, emotional, and neurological benefits of dancing with neurologist Berger, and dancer and patient Polai. They emphasize its therapeutic potential for people with neurological conditions and highlight how dance engages multiple brain functions and fosters social connection, making it a valuable tool for both patients and healthcare professionals.eanCampus access for Associate Members: If you are a member of a National Neurological Society in Europe, you are most likely already an Associate Member of the EAN and have an account for the eanCampus. If you have provided your email address to your National Neurological Society, it should already be in our database. Here is how you can access the eanCampus as an Associate Member:1. Enter the eanCampus2. Click on the Log In Button3. Log in with your MyEAN credentials and make use of the ‘forgot password'-functionality if necessaryIf you have trouble logging in, please get in contact with our Membership department (membership@ean.org) to cross-check if you are listed as an Associate Member to get access to eanCampus.

    Ep. 144: New Methods to Identify Larger Structural Variants

    Play Episode Listen Later Apr 20, 2025 19:17


    eanCampus access for Associate Members: If you are a member of a National Neurological Society in Europe, you are most likely already an Associate Member of the EAN and have an account for the eanCampus. If you have provided your email address to your National Neurological Society, it should already be in our database. Here is how you can access the eanCampus as an Associate Member:1. Enter the eanCampus2. Click on the Log In Button3. Log in with your MyEAN credentials and make use of the ‘forgot password'-functionality if necessaryIf you have trouble logging in, please get in contact with our Membership department (membership@ean.org) to cross-check if you are listed as an Associate Member to get access to eanCampus.

    Ep. 143: Novel Aspects of Repeat Expansions in Disease

    Play Episode Listen Later Apr 13, 2025 21:39


    Moderator: Francesca Magrinelli (London, UK)Guest: Andrea Cortese (London, UK)Join Magrinelli as she interviews Cortese about recent developments in the diagnosis and management of repeat expansion disorders, including diseases caused by repeats in non-coding genomic regions.eanCampus access for Associate Members: If you are a member of a National Neurological Society in Europe, you are most likely aleady an Associate Member of the EAN and have an account for the eanCampus. If you have provided your email address to your National Neurological Society, it should already be in our database. Here is how you can access the eanCampus as an Associate Member:1. Enter the eanCampus2. Click on the Log In Button3. Log in with your MyEAN credentials and make use of the ‘forgot password'-functionality if necessaryIf you have trouble logging in, please get in contact with our Membership department (membership@ean.org) to cross-check if you are listed as an Associate Member to get access to eanCampus.

    Ep. 142: Papers of the Month: Mismatch Repair & DNA Expansion in Huntington's Disease

    Play Episode Listen Later Apr 6, 2025 29:47


    Moderator: Jean-Marc Burgunder (Guemligen, Switzerland)Guest: Sandrine Humbert (Terville, France)In this week's episode, Burgunder and Humbert discuss the intriguing phenomenon of somatic expansion—the further increase of CAG repeat numbers in the gene involved in Huntington's disease, particularly in the striatum. They explore the molecular mechanisms behind this process, as addressed in two recent research papers.Please find here the papers discussed in this episode: Long somatic DNA-repeat expansion drives neurodegeneration in Huntington's diseaseand Distinct mismatch-repair complex genes set neuronal CAG-repeat expansion rate to drive selective pathogenesis in HD mice.eanCampus access for Associate Members: If you are a member of a National Neurological Society in Europe, you are most likely aleady an Associate Member of the EAN and have an account for the eanCampus. If you have provided your email address to your National Neurological Society, it should already be in our database. Here is how you can access the eanCampus as an Associate Member:1. Enter the eanCampus2. Click on the Log In Button3. Log in with your MyEAN credentials and make use of the ‘forgot password'-functionality if necessaryIf you have trouble logging in, please get in contact with our Membership department (membership@ean.org) to cross-check if you are listed as an Associate Member to get access to eanCampus.

    Ep. 141: Sodium Valproate in Men

    Play Episode Listen Later Mar 30, 2025 18:43


    EAN moderator: Barbara Tettenborn (St. Gallen, Switzerland)Guest: Tony Marson (Liverpool, UK)In this special episode, Tettenborn and Marson discuss sodium valproate treatment for epilepsy, focusing on its use in men. They try to deemphasize the potential risks of reduced fertility and the lately published potential neurodevelopmental effects on children born to men taking the drug, while also addressing the challenges in balancing treatment effectiveness and safety.

    Ep. 140: Transition from Childhood to Adulthood​

    Play Episode Listen Later Mar 23, 2025 20:21


    Moderator: Gudrun Gröppel​ (Linz, Austria)Guests: Dana Craiu​ (Bucharest, Romania), Thomas Berger​ (Vienna, Austria)This episode explores the challenges and solutions in transitioning young neurology patients from pediatric to adult care. Gröppel, Craiu and Berger discuss the importance of patient education, parental involvement, and collaborative efforts between pediatric and adult neurologists to ensure a smooth transition.If you want to participate in the mentioned survey, please see here: Transition from child to adult care in Pediatric Neurological Disorders in Europe – a joint EAN-EPNS Survey (available until 28 March 2025, 23:59).

    Ep. 139: Supporting Early Brain Development

    Play Episode Listen Later Mar 16, 2025 24:11


    Moderator: Leena Haataja (Helsinki, Finland)Guests: Silja Kosola (Helsinki, Finland), Liisa Lehtonen (Turku, Finland)In the third March episode Haataja, Kosola and Lehtonen focus on evidence-based antenatal and neonatal care practices to protect the brains and later outcomes of newborn infants. Furthermore, the phenomena and effects of excessive internet use, sleep deprivation and loneliness among school aged children and adolescents are discussed.

    Ep. 138: The Brain Health Mission Roadmap

    Play Episode Listen Later Mar 9, 2025 18:25


    Moderator: Elena Moro (Grenoble, France)Guest: Paul Boon​ (Gent, Belgium)This special episode of eanCast explores the Brain Health Roadmap Paper initiated by the European Academy of Neurology, highlighting its goals to advance brain health through research, education, policy initiatives, and public awareness. Prof. Moro (EAN President) and lead author, Prof. Boon (EAN Past President & BHM Co-Chair) discuss the urgent need for preventive measures, multidisciplinary collaboration, and the integration of brain health into neurology education and healthcare systems across Europe.For more information on the Brain Health Mission, please visit Brain Health Mission - ean.org. If you are interested to learn about the School Challenge mentioned in the episode, check it out here: Join the Brain Health School Challenge! - ean.org.

    Ep. 137: New Horizons on Treatment Choices of Rare Disorders

    Play Episode Listen Later Mar 2, 2025 25:15


    Moderator: Justyna Paprocka (Katowice, Poland)Guests: Laurent Servais (Oxford, UK), Michelangelo Mancuso (Pisa, Italy)In this first March episode, Paprocka, Mancuso, and Servais explore groundbreaking advancements in treating rare neurological disorders, focusing on paediatric and adolescent neurology. They discuss the role of gene therapy, emerging treatment strategies for neuromuscular disorders, and the evolving challenges of transitioning care from paediatric to adult neurology.

    Ep. 136: Susac Syndrome

    Play Episode Listen Later Feb 23, 2025 34:26


    Moderator: Andreu Vilaseca (Rochester, USA)Guest: Barbara Willekens (Edegem, Belgium) and Ilka Kleffner (Bochum, Germany)For the last February episode join Vilaseca, Willekens and Kleffner as they explore the complexities of Susac syndrome, a rare neuroimmunological disorder, through insightful case discussions and expert opinions. They discuss its diagnosis, pathophysiology, and the latest approaches to treatment.

    Ep. 135: Cannabis based medicine in neurology

    Play Episode Listen Later Feb 16, 2025 26:03


    Moderator: Yıldız Değirmenci (Istanbul, Türkiye)Guest: Natalia Szejko (Warsaw, Poland)In this episode Yıldız Değirmenci interviews Natalia Szejko about the controversial topic of cannabis-based medicine (CBM) in neurology.Değirmenci and Szejko raise awareness and resolve some important misconceptions, as questions about CBM are frequently asked by patients.

    Ep. 134: Recognizing autoinflammatory syndromes as a neurologist

    Play Episode Listen Later Feb 9, 2025 20:39


    Moderator: João Moura (Porto, Portugal)Guest: Jeroen Kerstens (Edegem, Belgium)In this episode João Moura and Jeroen Kerstens focus on autoinflammatory syndromes. They discuss how to diagnose them and how they differ from autoimmune disorders, highlighting that autoinflammatory syndromes often present neurological features, and targeted treatment may prevent irreversible organ damage. Please find the article mentioned in the episode here: Autoinflammatory syndromes in neurology: when our first line of defence misbehaves . 

    Ep. 133: Autoimmune encephalitis

    Play Episode Listen Later Feb 2, 2025 31:32


    EAN moderator: Maria Pia Giannoccaro (Bologna, Italy)Guests: Alberto Vogrig (Udine, Italy), Maarten Titulaer (Rotterdam, The Netherlands)In this first episode of the Neuroimmunology series, Maria Pia Giannoccaro talks with Alberto Vogrig and Maarten Titulaer about the current approach to diagnosis, acute treatment and long-term management of autoimmune encephalitis.

    Ep. 132: Paper reviews on post-pandemic neurology risks and ischemic stroke care guidelines

    Play Episode Listen Later Jan 26, 2025 27:51


    Moderator: Prof. José Ferro (Lisbon, Portugal)Guests: Saša Filipović (Belgrade, Serbia), Charlotte Lens (Leuven, Belgium) In this episode, first, join Ferro and Filipović as they discuss updated consensus recommendations from the COVID Task Force on managing chronic neurological conditions during and after COVID-19, covering treatment strategies, vaccination guidance, and approaches to long COVID care. Then, join Ferro and Lens as they explore research on optimizing ischemic stroke care, focusing on quality improvement, patient-reported outcomes and experiences, and insights from Lens' paper on ischemic stroke guidelines and their applicability across diverse healthcare settings. Please find the papers discussed in the episode here:• Management of patients with neurological diseases considering post-pandemic coronavirus disease 2019 (COVID-19) related risks and dangers — An updated European Academy of Neurology consensus statement• From guidelines to clinical practice in care for ischaemic stroke patients: A systematic review and expert opinion

    Ep. 131: Assessment of prognosis in TBI

    Play Episode Listen Later Jan 19, 2025 26:28


    Moderator: Luca Sebastianelli (Vipiteno, Italy)Guest: Olli Tenovuo (Turku, Finland)In this episode Luca Sebastianelli and Olli Tenovuo discuss the many factors that influence the recovery and thus outcome after a TBI, including the use of available assessment tools.

    Ep. 130: The juvenile brain

    Play Episode Listen Later Jan 12, 2025 26:54


    EAN Moderator: Jana Midelfart Hoff (Bergen, Norway)Guest: Marte Roa Syversen (Drammen, Norway)In this week's episode Jana Midelfart Hoff and Marte Roa Syversen discuss what happens in the brain when a calm 10-year-old evolves into an emotional volcano of thirteen. They explore the structural changes in the brain and their effect when going from child to grown-up.

    Ep. 129: From then to now: Neurology through the years

    Play Episode Listen Later Jan 5, 2025 32:47


    EAN moderator:  Thomas Berger (Vienna, Austria)Guest: Gereon Fink (Cologne, Germany)In this first eanCast episode of 2025, Thomas Berger and Gereon Fink discuss how dramatically Neurology has changed due to fundamental breakthroughs in understanding the pathophysiology and pathomechanisms of neurological disorders, enabling the development of specific novel treatments, eventually resulting in personalized approaches. Thomas Berger and Gereon Fink reflect upon how methodological advances have catalyzed this progress and how an exact understanding of disease pathology also informs the prevention of neurological diseases, opening avenues for a new era of neurology.

    neurology ean thomas berger
    Ep. 128: Inclusive Communication with sexual and gender minorities in Neurology

    Play Episode Listen Later Dec 29, 2024 22:22


    Moderator: Francesco Pasini (Milano, Italy)Cianán Russell (Brussels, Belgium) In this last episode of the year, Francesco Pasini and Cianán Russel talk about inclusive communication with sexual and gender minorities in Neurology. The topics discussed include the stigma experienced by the LGBTI population in healthcare, some suggestions for inclusive communication with patients, and reflections on the need to explore new languages and approaches for diverse patient populations.eanCast Listener Feedback Survey: https://www.surveymonkey.com/r/eanCast

    Ep. 127: Sex and gender differences in Parkinson's disease

    Play Episode Listen Later Dec 22, 2024 26:45


    Moderator: Vanessa Carvalho (Lisbon, Portugal) Guest: Angelo Antonini (Padua, Italy)This week Vanessa Carvalho hosts expert Angelo Antonini as they review not only prevalence but also sex and gender differences in response to treatment, and the treatment of specific populations such as pregnant women. They also approach the bias in enrollment of women living with PD in clinical trials, its main causes and the main consequences of this underrepresentation. Please find suggested further reading on this episode here: Further Reading on eanCast Episodes - ean.orgeanCast Listener Feedback Survey: https://www.surveymonkey.com/r/eanCast

    Ep. 126: Sex and gender differences in Alzheimer's disease

    Play Episode Listen Later Dec 15, 2024 24:35


    Moderator: Luca Cuffaro (Milano, Italy)Guest: Julie Novakova Martinkova (Prague, Czechia) In this episode, Dr. Luca Cuffaro and Dr. Julie Novakova Martinkova discuss sex and gender differences in Alzheimer's disease. Topics discussed include differences in Alzheimer's disease epidemiology, progression, biomarkers, clinical trials, and prospective treatments, with a special focus on their potential biological mechanisms. Please find suggested further reading on this episode here: Further Reading on eanCast Episodes - ean.orgeanCast Listener Feedback Survey: https://www.surveymonkey.com/r/eanCast

    Ep. 125: Navigating Gender Differences in Neurology Careers

    Play Episode Listen Later Dec 8, 2024 24:09


    Moderator: Alice Accorroni (Geneva, Switzerland)Guest: Marianne de Visser (Amsterdam, Netherlands)In this week's episode Alice Accorroni and Marianne de Visser discuss the multifaceted impact of gender on career trajectories in neurology, examining mentorship dynamics and the intersectionality of gender with ethnicity and socioeconomic background. They discuss the importance of support networks, education, and fostering a gender-sensitive culture. Highlighting the value of representation in leadership, they share insights and practical solutions to promote diversity, inclusion, and acceptance.eanCast Listener Feedback Survey: https://www.surveymonkey.com/r/eanCast

    Ep. 124: Insights into the EAN Leadership Programme

    Play Episode Listen Later Dec 1, 2024 25:25


    Ean Moderator: Anja Sander (Vienna, Austria)Guest: Peter Dedeken (Sint-Katelijne-Waver, Belgium)Guest: Vanessa Carvalho (Lisbon, Portugal)This week we are happy to share an episode about the EAN Leadership Programme. EAN Executive Director, Anja Sander, hosts two participants of the current round of the Leadership Programme: Peter Dedeken and Vanessa Carvalho. They share their motivation, learnings and benefits of participating in the programme, not only for leading others, buts also for leading themselves. The application for the next round of the Leadership Programme opens on 2 December 2024 - please find all information about the application procedure here: EAN Leadership Programme - ean.orgFor more insights into the programme, see this article from another participant, Raphael Wurm: Why I applied for the EAN Leadership Programme and what I have learned - eanpagesThe link to the mentioned burnout study can be found here: Education Research: Impact of Burnout on Neurology Residents and Research Fellows in Europe | Neurology Education eanCast Listener Feedback Survey: https://www.surveymonkey.com/r/eanCast

    Ep. 123: News on the risk of malformations and developmental impairment among the offspring of male patients under antiseizure medication​

    Play Episode Listen Later Nov 24, 2024 16:53


    Moderator: Bernhard J. Steinhoff (Kehl-Kork, Germany)Guest: Jakob Christensen (Aarhus, Denmark)In this last November episode Bernhard Steinhoff and Jakob Christensen give an update on new data concerning the risk of the offspring of male patients under antiseizure medications. They discuss that the warnings of the EMA about autism spectrum disorders and cognitive impairment that raised major concern now appear less intimidating due to recently published results from a huge Scandinavian registry study.

    Ep. 122: News on the risk of malformations and developmental impairment among the offspring of female patients under antiseizure medication

    Play Episode Listen Later Nov 17, 2024 18:13


    Moderator: Bernhard J. Steinhoff (Kehl-Kork, Germany)Guest: Jakob Christensen (Aarhus, Denmark)This week Bernhard Steinhoff talks with Jakob Christensen about the latest news on the risk of antiseizure medications in pregnancy and beyond. They mention new data on teratogenicity and the increased probability of autism spectrum disorders and cognitive impairment of the offspring.

    Ep. 121: New developments concerning neurostimulation in epilepsy​

    Play Episode Listen Later Nov 10, 2024 21:26


    Moderator: Bernhard J. Steinhoff (Kehl-Kork, Germany)Guest: Kristl Vonck (Gent, Belgium)In this episode, Bernhard Steinhoff speaks with expert Kristl Vonck on the latest advancements in neurostimulation therapies for epilepsy. They explore how innovations in vagus nerve and deep brain stimulation are enhancing personalized treatment approaches, offering new hope for epilepsy patients resistant to traditional therapies.

    Ep. 120: New developments of long- and ultralong EEG in epileptology​

    Play Episode Listen Later Nov 3, 2024 20:12


    Moderator: Bernhard J. Steinhoff (Kehl-Kork, Germany)Guest: Andreas Schulze-Bonhage (Freiburg, Germany)In this episode Bernhard J. Steinhoff and Andreas Schulze-Bonhage discuss the new fascinating perspectives and possibilities of EEG technologies that allow high-class long and ultra-long recordings. Schulze-Bonhage shares these new developments of a method still uniquely important for epileptologists.

    Ep. 119: Phase 2 HOPE clinical trial results

    Play Episode Listen Later Oct 27, 2024 23:46


    Moderator: Theodoros M. Mavridis (Dublin, Ireland)Guest: Messoud Ashina (Glostrup, Denmark)In this episode Theodoros M. Mavridis and Messoud Ashina delve into the findings of the Phase 2 HOPE clinical trial, which assesses the efficacy and safety of Lu AG09222, a monoclonal antibody that targets the PACAP pathway. They explore the potential of this innovative treatment for migraine prevention while highlighting the critical role of the PACAP pathway in migraine pathophysiology.

    Ep. 118: Rare causes of myelopathy

    Play Episode Listen Later Oct 20, 2024 23:49


    Moderator: Roland Wiest (Bern, Switzerland)Guest: Randolf Klingebiel (Bielefeld, Germany)In this episode, Roland Wiest and Randolf Klingebiel explore rare causes of myelopathy, a challenging condition due to its infrequent occurrence and diverse origins. They discuss the diagnostic workup, imaging protocols, and differential diagnoses, emphasizing the importance of collaboration between neurologists and neuroradiologists in managing these complex cases.

    Ep. 117: Imaging of spinal cord ischemia

    Play Episode Listen Later Oct 13, 2024 22:57


    Moderator: Raphael Wurm (Vienna, Austria)Guest: Majda Thurnher (Vienna, Austria)For this episode, Raphaela Wurm welcomes Majda Thurnher to dive into the challenges and joys of diagnosing spinal cord ischemia as theyexplore MRI protocols, key imaging findings, and the impact of diffusion-weighted imaging.

    Ep. 116: ​Indications and pitfalls of spinal imaging​

    Play Episode Listen Later Oct 6, 2024 22:31


    Moderator: Raphael Wurm (Vienna, Austria)Guest: Dr. Wolfgang Marik (Vienna, Austria)In this episode, Raphael Wurm and Wolfgang Marik explore key neuroimaging techniques for the spine, focusing on when to use CT, MRI, myelography, and spinal arteriography. They discuss how to choose the right technology and address common challenges that can be avoided with proper indications.

    Ep. 115: Can we prevent dementia?

    Play Episode Listen Later Sep 29, 2024 21:36


    EAN moderator: Youssuf Saleh (Oxford, United Kingdom)Guest: Sebastiaan Engelborghs (Brussel, Belgium)In this episode Youssuf Saleh and Sebastiaan Engelborghs discuss dementia prevention, with particular reference to the recently published lancet commission report on dementia prevention, intervention and care. Key areas of discussion include what those risks are, how they can be mitigated and what adaptations the field of neurology and public health need to minimise the burden of dementia in aging populations.

    Ep. 114: Neurological Prognosis and Treatment after Cardiac Arrest

    Play Episode Listen Later Sep 22, 2024 28:33


    EAN moderator: Marian Galovic (Zurich, Switzerland)Guest: Michel van Putten (Enschede, The Netherlands) In this episode, Marian Galovic talks with Prof. Michel van Putten about the effects of cardiac arrest on the brain. They highlight the role of EEG in assessing long-term prognosis following cardiac arrest and discuss the treatment of rhythmic or periodic EEG patterns.

    Ep. 113: New EAN Guideline on the Management of Amyotrophic Lateral Sclerosis

    Play Episode Listen Later Sep 15, 2024 20:19


    Moderator: Federica Agosta (Milan, Italy)Guest: Philip van Damme (Leuven, Belgium) In this week's episodes Federica Agosta hosts Philip van Damme as they discuss the new EAN Guideline on the Management of Amyotrophic Lateral Sclerosis. Find more information here.

    Ep. 112: Brain Circuits: Principles and Translational Applications

    Play Episode Listen Later Sep 8, 2024 26:54


    EAN moderator: Youssuf Saleh (Oxford, United Kingdom)Guest: Thanh Doan (Trondheim, Norway)For this episodes Youssuf Saleh is joined by Thanh Doan as they discuss the role of brain circuits in neuroscience and how they can be used to advance both our understanding of disease and lay foundations for circuit-based treatments including neuromodulation.

    Ep. 111: ECTRIMS-EAN Vaccination Consensus Statement

    Play Episode Listen Later Sep 1, 2024 32:47


    EAN Moderator: Melinda Magyari (Copenhagen, Denmark)Special Moderator: Brett Drummond (Melbourne, Australia)Guest: Susana Otero (Barcelona, Spain)In this episode eanCast: Weekly Neurology is joined by The ECTRIMS Podcast. Hosts Melinda Magyari and Brett Drummond talk about the ECTRIMS-EAN Vaccination Consensus Statement with lead author Susana Otero. Find the full article here.

    Ep. 110: Family Planning Management in Multiple Sclerosis

    Play Episode Listen Later Aug 25, 2024 21:38


    Moderator: Melinda Magyari (Copenhagen, Denmark)Guest: Celia Oreja-Guevara (Madrid, Spain)In this last August episode Melinda Magyari hosts Celia Oreja-Guevara as they explore the impact of MS on women's fertility, the shift in advice regarding pregnancy, and how pregnancy affects MS activity. They also discuss the importance of consulting a neurologist, considerations for artificial reproduction techniques, and recommendations for disease-modifying therapies, including treating relapses during pregnancy and breastfeeding.

    Ep. 109: The Impact of Aging on MS: Comorbidities, Polypharmacy and Disease Modifying Treatments

    Play Episode Listen Later Aug 18, 2024 23:30


    Moderator: Melinda Magyari (Copenhagen, Denmark)Guest: Thomas Berger (Vienna, Austria)Melinda Magyari and her guest Thomas Berger talk about how aging affects MS progression and management, focusing on immunosenescence's impact on the immune response and DMT effectiveness. They cover the rise of comorbidities in older MS patients, the challenges of using DMTs over age 55, the lack of clinical trials for this age group, and share lifestyle tips to improve quality of life and health outcomes.

    Ep. 108: Central Vein Sign and Chronic Active Lesions: Relevance for Diagnosis and Prognosis in Multiple Sclerosis

    Play Episode Listen Later Aug 11, 2024 27:07


    Moderator: Melinda Magyari (Copenhagen, Denmark)Guest: Nikolaos Grigoriadis (Thessaloniki, Greece)Melinda Magyari hosts Paolo Preziosa as they delve into the significance of central vein sign and chronic active lesions in multiple sclerosis diagnosis and prognosis. They explore how these MRI biomarkers enhance diagnostic accuracy and predict disease progression, emphasizing their potential clinical relevance and the need for further research to optimize MS treatment strategies.

    Ep. 107: Is EBV the Key Player in Multiple Sclerosis Pathogenesis?

    Play Episode Listen Later Aug 4, 2024 25:32


    Moderator: Melinda Magyari (Copenhagen, Denmark)Guest: Nikolaos Grigoriadis (Thessaloniki, Greece)Follow Melinda Magyari and her guest Nikolaos Grigoriadis in the first MS episode of this month as they explore the Epstein-Barr Virus and its potential link to multiple sclerosis. They discuss how EBV might trigger or worsen MS, the challenges in confirming this connection, and implications for treatment and prevention. Other MS risk factors, such as genetics, environment, vitamin D levels, and lifestyle, are also covered.

    Ep. 106: Phenoconversion in Pure Autonomic Failure

    Play Episode Listen Later Jul 21, 2024 28:54


    Moderator: Anne Pavy-Le Traon (Toulouse, France)Guests: Giovanna Calandra-Buonaura (Bologna, Italy) and Valeria Iodice (London, United Kingdom) In this week's podcast episode Anne Pavy-Le Traon hosts two guests, Giovanna Calandra Buonaura and Valeria Iodice, as they discuss a hot topic related to Phenoconversion in Pure Autonomic Failure (PAF). They highlight the natural history of PAF and the importance of recognising this disease as a possible prodromal/ premotor phase of other alpha synucleinopathies. They discuss novel clinical and multimodal biomarkers in early diagnosis of these disorders.

    Ep. 105: Gastrointestinal Autonomic Dysfunction in Movement Disorders

    Play Episode Listen Later Jul 14, 2024 23:49


    Moderator: Cristian Falup-Pecurariu (Brasov, Romania)Guest: Valentina Leta (Milan, Italy)In this episode, Cristian Falup-Pecurariu discusses with Valentina Leta the relationship between gastrointestinal dysfunction and movement disorders with a focus on Parkinson's disease. They explore the impact of gastrointestinal dysfunction as part of dysautonomia in people with Parkinson's disease, other neurodegenerative diseases, and the importance of identifying and managing these symptoms to improve their quality of life.

    Ep. 104: Cardiovascular Autonomic Dysfunction

    Play Episode Listen Later Jul 7, 2024 30:06


    Moderator: Cristian Falup-Pecurariu (Brasov, Romania)Guests: Alessandra Fanciulli (Innsbruck, Austria) and Roland Thijs (Heemstede, The Netherlands)In this second episode of July, Cristian Falup-Pecurariu hosts Alessandra Fanciulli and Roland Thijs. They delve into the topic of Cardiovascular Autonomic Dysfunction and cover symptoms, diagnosis, and treatment of conditions like syncope and orthostatic hypotension, emphasizing their significance in neurodegenerative disorders and the importance of distinguishing these autonomic failures in clinical practice.

    Ep. 103: Post-COVID Autonomic Dysfunction

    Play Episode Listen Later Jun 30, 2024 18:45


    Moderator: Anne Pavy-Le Traon (Toulouse, France)Guests: Diogo Carneiro (Coimbra, Portugal); Fabian Leys (Innsbruck, Austria)In this episode, Anne Pavy-Le Traon talks with Diogo Carneiro and Fabian Leys about the Post-Covid Autonomic Dysfunction, a disease that appeared during the recent COVID-19 pandemics but is still present in a large number of individuals. They highlight the syndromic constellation of this entity which affects different body organs and the general principles of its management.

    Ep. 102: Acute symptomatic seizures

    Play Episode Listen Later Jun 23, 2024 22:23


    Release Date: 24.06.2024Moderator: Barbara Tettenborn (St. Gallen, Switzerland)Guest: Marian Galovic (Zurich, Switzerland)In this episode Barbara Tettenborn talks with Dr. Marian Galovic about acute symptomatic seizures, a frequent but commonly misunderstood topic. They highlight the impact of acute symptomatic seizures on outcomes and brain health, their implications for developing epilepsy and the resulting treatment considerations.

    Ep. 101: MS in Children

    Play Episode Listen Later Jun 16, 2024 27:14


    Moderator: Andrew Chan (Bern, Switzerland)Guests: Barbara Kornek (Vienna, Austria) and Fredrik Sandesjo (Stockholm, Sweden)Pediatric onset multiple sclerosis (POMS) is increasingly recognized as a non-benign condition which requires consequent disease modifying treatment. In this special episode Andrew Chan hosts Barbara Kornek and Fredrik Sandesjö. They discuss epidemiological, biological and clinical characteristics of POMS, and highlight early highly effective therapy in this vulnerable patient group and the treatment in POMS.

    Ep. 100: Neurology: Past and Future

    Play Episode Listen Later Jun 9, 2024 23:24


    Moderator: Barbara Tettenborn (St. Gallen, Switzerland)Guests: Claudio Bassetti (Bern, Switzerland) and Elena Moro (Grenoble, France)We are thrilled to announce a milestone celebration: the 100th episode of eanCast!In this special episode, we are honoured to welcome two distinguished guests. The past president of EAN, Prof. Claudio Bassetti, who will share insights into the challenges faced and achievements accomplished during his tenure, along with exciting projects that have made a lasting impact. Additionally, we will be joined by the first female future president of EAN: Prof. Elena Moro, who will discuss her vision and plans for her upcoming presidency.

    Ep. 99: Gastro and Brain Health

    Play Episode Listen Later Jun 2, 2024 17:57


    Moderator: Barbara Tettenborn (St. Gallen, Switzerland)Guest: Jutta Keller (Hamburg, Germany)In this episode of eanCast and UEG Talks, host Prof. Barbara Tettenborn from the EAN and guest Prof. Jutta Keller from UEG discuss neuro-gastroenterology, focusing on the gut-brain axis and its implications for various gastrointestinal and neurological disorders. They explore the influence of the microbiome on gut function, the impact of diet on brain health, and strategies for managing gastrointestinal symptoms in patients with neurological conditions like Parkinson's disease.United European Gastroenterology (UEG) is a strategic partner of the Brain Health Mission (BHM). This episode is brought to you by the Brain Health Mission. 

    Ep. 98: Recommendations on Organizing Headache Care: how to increase access and offer value-based healthcare in headache

    Play Episode Listen Later May 26, 2024 19:48


    Moderator: Alicia Gonzalez (Madrid, Spain)Guest: Christian Lampl (Linz, Austria)This last May episode features Alicia González Martínez and her guest Prof. Christian Lampl as they discuss organising headache care, focusing on increasing access and offering value-based healthcare. They delve into strategies to improve the delivery, efficiency, and cost-effectiveness of headache management, aiming to enhance patient well-being and integration of headache care into existing healthcare systems.

    Ep. 97: Preclinical, translational and clinical research: insights from animal models and humans

    Play Episode Listen Later May 19, 2024 16:48


    Moderator: Daniele Martinelli (Pavia, Italy)Guest: Raquel Gil-Gouveia (Oeiras, Portugal)Guest: Antoinette Maassen van den Brink (Rotterdam, The Netherlands)Join us in this episode as Daniele Martinelli engages in a dialogue with esteemed experts, Prof. Antoinette Maassen van den Brink and Dr. Raquel Gil-Gouveia.They delve into animal models—our window into the brain's hidden mechanisms. These models reveal neurotransmitter dynamics and potential triggers, paving the way for novel therapies. Additionally, they explore gender-specific nuances, shaping the understanding and personalized management strategies. By bridging theory to practice, they emphasize collaboration—a path toward better patient outcomes, alleviating the burden of this debilitating condition.

    Ep. 96: Migraine Guideline review: what is published? And what are we working on?

    Play Episode Listen Later May 12, 2024 16:48


    Moderator: Anna Gryglas-Dworak (Wroclaw, Poland)Guest: Dimos-Dimitrios Mitsikostas (Athens, Greece)This podcast episode presents the current guidelines of the European Headache Federation (published in 2021, updated in 2022) and the American Headache Society (2024) on migraine treatment. Acute and preventive as well as new and old options are discussed.

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