Podcasts about translational

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Best podcasts about translational

Latest podcast episodes about translational

Neurocareers: How to be successful in STEM?
Connectomics in Pediatric Epilepsy: A Clinical Research Scientist's Career with Puck Reeders, PhD

Neurocareers: How to be successful in STEM?

Play Episode Listen Later May 18, 2025 78:34


How do you turn massive clinical imaging data into insights that change lives? What does it take to move from a psychology undergrad to a pioneering role in pediatric brain research? And how can coding, connectomics, and curiosity shape a meaningful clinical career in neuroscience? In this inspiring episode of Neurocareers: Doing the Impossible!, we sit down with Dr. Puck Reeders, Senior Neuroscience Research Scientist at the Brain Institute at Nicklaus Children's Hospital. From her early days in Curacao to building novel neuroimaging pipelines in one of the nation's oldest pediatric epilepsy programs, Dr. Reeders shares her unique career path—and how she helps decode complex brain networks to improve surgical outcomes for children with intractable epilepsy. We explore: How connectomics and diffusion imaging guide surgical planning Her innovative research on white matter networks and neuromodulation responses The steep but rewarding path from zero coding skills to advanced tractography Tips for transitioning from psychology to clinical neuroscience Career advice for anyone eager to enter research-focused medical settings Whether you're a student exploring future careers, a neuroscientist curious about clinical impact, or just fascinated by how science meets medicine—you'll walk away informed and inspired. Chapters: 00:00:00 - Insights from a Neuroscience Research Scientist 00:03:00 - Functional Mapping Techniques for Epilepsy 00:08:43 - Transitioning from Medical School to Psychology 00:13:10 - Research Gaps in Epilepsy 00:17:10 - Understanding Connectomics in Epilepsy Treatment 00:21:53 - Combining Imaging Techniques in Research 00:24:50 - Coding Challenges in Research 00:27:12 - Coding Journey in Neuroscience 00:28:51 - Learning to Code: A Personal Journey 00:32:39 - The Importance of Networking 00:34:30 - Art's Role in Science Communication 00:37:38 - Landing a Job Through Networking 00:41:22 - Research Opportunities in Connectomics 00:46:49 - Exploring Diverse Career Opportunities 00:51:38 - Job Search Tips and Strategies 00:54:39 - Tips for Job Applications and Interviews 00:59:46 - From Medicine to Neuroscience Research 01:02:06 - Clinical Research and Pediatric Epilepsy About the Podcast Guest: Dr. Puck Reeders is a Senior Neuroscience Research Scientist at the Brain Institute at Nicklaus Children's Hospital in Miami, Florida https://www.nicklauschildrens.org/home Her work focuses on investigating aberrant brain networks in children with intractable epilepsy, applying advanced neuroimaging techniques to improve clinical outcomes in pediatric neurology. Originally from the Netherlands and raised on the island of Curaçao, Dr. Reeders brings a global perspective to her research. She holds a Bachelor of Science in Psychology and Chemistry from the University of Miami, and a PhD in Cognitive Neuroscience from Florida International University, where she also completed her postdoctoral training in the Allen Neurocircuitry and Cognition Lab. Dr. Reeders has over nine years of experience working with functional MRI (fMRI) and diffusion-weighted imaging (DWI) in both adults and children. Her current research explores the structural connectomics of pediatric epilepsy, the development of clinical imaging pipelines to detect white matter abnormalities, cortical dysplasias, and automated SPECT subtractions—bringing together cutting-edge science with translational clinical impact. Her expertise spans: Neuroimaging and clinical pipeline development Data analysis and scientific coding Translational neuroscience and surgical planning support Research project design and academic mentoring Outside of the lab, Dr. Reeders shares insights into neuroscience careers and research life on her educational Instagram: @Drpucky You can also connect with her professionally on LinkedIn:  https://www.linkedin.com/in/puckreeders/  About the Podcast Host: The Neurocareers podcast is brought to you by The Institute of Neuroapproaches (https://www.neuroapproaches.org/) and its founder, Milena Korostenskaja, Ph.D. (Dr. K), a career coach for people in neuroscience and neurotechnologies. As a professional coach with a background in neurotech and Brain-Computer Interfaces, Dr. K understands the unique challenges and opportunities job applicants face in this field and can provide personalized coaching and support to help you succeed. Here's what you'll get with one-on-one coaching sessions from Dr. K: Identification and pursuit of career goals Guidance on job search strategies, resume, and cover letter development Neurotech / neuroscience job interview preparation and practice Networking strategies to connect with professionals in the field of neuroscience and neurotechnologies Ongoing support and guidance to help you stay on track and achieve your goals You can always schedule a free neurocareer consultation/coaching session with Dr. K at https://neuroapproaches.as.me/free-neurocareer-consultation Subscribe to our Nerocareers Newsletter to stay on top of all our cool neurocareers news at updates https://www.neuroapproaches.org/neurocareers-news

The Medical Journal of Australia
Episode 577: MJA Podcasts 2025 Episode 6 - Translational Orthopaedic Research in Practice

The Medical Journal of Australia

Play Episode Listen Later Apr 13, 2025 29:33


Today we are exploring the topic of Translational Orthopaedic Research in Practice.This podcast is sponsored by Macquarie University Hospital, part of MQ Health - a trailblazer in healthcare, education and research.Joining me is Associate Professor Sumit Raniga who is an award winning sub-specialist internationally recognised. orthopaedic shoulder and elbow surgeon. He is the Director of the Translational   Orthopaedic Research Lab and Head of Upper Limb Surgery and Therapy at Macquarie University Hospital. Dr Michael Dan is a lower limb orthopaedic specialist with further formal subspeciality training from the Lyon Knee School in France. 

Dementia Researcher
Of Mice and Men… and Toxins: The Environmental Link to Dementia

Dementia Researcher

Play Episode Listen Later Mar 29, 2025 45:46


In this episode of the Dementia Researcher Podcast, guest host Dr Sam Moxon is joined by Dr Adam Schuller, Dr Savannah Rocha-Wrigley, and Megan Hager from Colorado State University's Tjalkens Lab to explore the significant yet often overlooked impact of environmental toxins on dementia and neurodegenerative diseases. This fascinating discussion sheds light on how substances such as pesticides, heavy metals, wildfire smoke, and air pollution can trigger changes in glial cells, such as astrocytes and microglia, which may lead to dementia. The experts share insights into groundbreaking experimental models, imaging technologies, and the importance of early intervention and prevention strategies to reduce toxin-related risks. -- Key Topics:

RARECast
Seeing the Cell and Gene Therapy Translational Divide as an Opportunity

RARECast

Play Episode Listen Later Mar 20, 2025 33:58


Emerging cell and gene therapies represent areas of great promise for people with rare, genetic diseases, but the translation gap for these medicines can leave them stalled at the lab. Mass General Brigham in 2022 launched the Gene and Cell Therapy Institute, a research hub dedicated to advancing gene and cell therapies for various diseases to bridge the divide between academic labs and clinical development of therapies. The institute brings together more than 500 researchers and clinicians and boasts unique assets, such as its RNA Therapeutics Core, which enable it to produce cutting-edge circular RNA on-site. We spoke to Nathan Yozwiak, head of research at the Mass General Brigham Cell and Gene Therapy Institute, about the need it is seeking to address, how the institute operates, and what it might do to enable the development of bespoke therapies for ultra-rare diseases.

The EMJ Podcast: Insights For Healthcare Professionals
Onc Now: Episode 13: Metastatic Colorectal Cancer Unravelled

The EMJ Podcast: Insights For Healthcare Professionals

Play Episode Listen Later Mar 19, 2025 47:01


In this episode of the Onc Now Podcast, host Jonathan Sackier is joined by Sebastian Stintzing, Head of Department of Medicine, Division of Hematology, Oncology, and Cancer Immunology, Charité - Universitäetsmedizin Berlin, Germany. They discuss the most promising developments in gastrointestinal oncology, with particular focus on the role of personalised medicine in metastatic colorectal cancer treatment.  Timestamps:    00:00 – Introduction  03:04 – Impactful developments in gastrointestinal oncology  08:53 – Issues with funding clinical trials  14:17 – Designing trials and the importance of patient advocacy   17:11 – Translational biomarker programs  19:58 – Treatment strategies for RAS wild-type tumours  22:28 – The FIRE-4.5 study on mutant metastatic colorectal cancer  29:50 – Genetic profiling and epigenomics  33:12 – Precision medicine and immune oncology in GI cancers  34:52 – Colorectal cancer in younger adults  34:54 – Raising awareness for early screening of GI cancers 

The Sim Cafe~
Advancing Patient Care Through Translational Simulation: Insights and Strategies

The Sim Cafe~

Play Episode Listen Later Feb 25, 2025 27:15 Transcription Available


Send us a textWhat if you could transform patient care with the power of simulation? Join us for an enlightening conversation with Lisa Paganotti from George Washington University, an expert in simulation education, as she shares her inspiring journey from the emergency department to becoming a leader in the field. Lisa unpacks the concept of translational simulation, explaining how it bridges the gap between theoretical learning and practical patient outcomes. With her extensive experience, Lisa delves into the structured stages of integrating simulation into clinical practice, emphasizing the critical role of theories and conceptual models.We also tackle the hurdles and triumphs of implementing effective translational simulation programs. This episode offers actionable insights into overcoming historical resistance and sustainability challenges, with practical advice from 18 seasoned experts. Discover how to develop a robust dissemination plan and maintain successful simulation-based education programs. Lisa Ann Buckley adds her perspective as a site reviewer, focusing on the significance of systems integration for accreditation. Whether you're just starting or looking to enhance existing programs, this conversation promises to equip you with valuable strategies for advancing simulation in healthcare.Lisa Paganotti's email- Lisaannbuckley@gwu.eduInnovative SimSolutions.Your turnkey solution provider for medical simulation programs, sim centers & faculty design.

The Biotech Startups Podcast

“I didn't set out to be an entrepreneur, but when I couldn't find a company doing what I believed in, I built my own.” In part two of our conversation with Kate Yen, Founder and CEO of Auron Therapeutics, we explore her journey from leading a novel cancer therapy program at Agios to founding her own biotech company. Kate shares insights into drug development, clinical trials, and the business of biotech, highlighting the importance of translational biology, strategic partnerships, and lean operations in building a successful biotech startup. Kate earned her Ph.D. in Biological Chemistry from UCLA, where she also completed her postdoc. Before Auron, she held roles at Merck and as a UCLA professor before joining Agios Pharmaceuticals, where she led the IDH translational research team behind two FDA-approved IDH mutant inhibitors and co-led the discovery of vorasidenib, a promising glioma therapy now in clinical development.

Sleep On It
Dr Victoria Revell, Associate Professor in Translational Sleep and Circadian Physiology shares cutting edge research into sleep, health and performance.

Sleep On It

Play Episode Listen Later Feb 11, 2025 41:24


Dr Victoria Revell, is an Associate Professor in Translational Sleep and Circadian Physiology at the University of Surrey. Dr Revell has over 20 years of experience in  conducting cutting edge research in the arena of sleep, health and performance.   In the episode, Sophie and Victoria discuss circadian rhythms, why daylight savings time may be bad news for our health, and the pros and cons of light and caffeine for managing our energy. Find out more about Victoria's work and research here https://www.surrey.ac.uk/people/victoria-revell Sleep On Series 3 is brought to you by the Sleep Charity and sponsored by Lumie.

Simulcast
199 Better airway management through translational simulation in a rural ED

Simulcast

Play Episode Listen Later Feb 5, 2025 40:04


Ever felt that preparing equipment for advanced airway management in your ED is ‘messy'?  In this episode Vic interviews Dr Ava Butler, an emergency doctor and QI/ simulation practitioner from rural British Columbia. We discussed her recent article about how equipment re-design and translational simulation was used to dramatically improve preparation speed and staff level of comfort with advanced airway management.  The conversation was informative and inspiring. We talked about the liberating structures process of brainstorming ideas for improvement, the role of patient partners in improvement, the hierarchy of interventions in quality improvement, and the significance of qualitative measures and stories in improvement efforts.  We marvelled at the dramatic improvements they achieved using a color-coded airway cart and translational simulation; a 76% reduction in time taken to prepare airway equipment, and significant improvements in staff comfort and team culture. EM sim cases got an honourable mention

The EMJ Podcast: Insights For Healthcare Professionals
Onc Now: Episode 10: Transforming Breast Cancer Care

The EMJ Podcast: Insights For Healthcare Professionals

Play Episode Listen Later Feb 5, 2025 43:07


In this episode of Onc Now, Jonathan is joined by Dr Dave Cescon, a Medical Oncologist and Clinician Scientist at the Princess Margaret Cancer Centre, Toronto, Canada. Together, they explore the transformative impact of CDK4/6 inhibitors, challenges in liquid biopsy research, and the potential of mRNA vaccines in oncology.  Timestamps: (02:44) -Swimming in Toronto: Competitive vs. Open Water  (08:06) -From Internal Medicine to Breast Cancer Research  (14:09) -Translational research and circulating tumour DNA  (19:53) -The role of CDK4/6 inhibitors in breast cancer  (29:04) -FDA approval of ribociclib for high-risk early breast cancer  (31:45) -The future of mRNA vaccines for personalised cancer care  (37:34) -Dave's research challenges and innovations  (39:13) -Three wishes for healthcare 

Penn Undergraduate Biotech Society (PUBS) Podcast
Translational Genomics Research for Diabetic Retinopathy with Dr. Sampath Rangasamy

Penn Undergraduate Biotech Society (PUBS) Podcast

Play Episode Listen Later Jan 31, 2025 35:51


In this episode, Siddharth Adda and Dr. Sampath Rangasamy, Research Associate Professor at the Translational Genomics Research Institute sit down to discuss his journey researching therapeutics for diabetic retinopathy. Dr. Rangasamy, a lifelong Type-I diabetic, reveals how the disease motivated him to conduct research on angiopoietin-2, and contribute towards a potential therapeutic.

GU Cast
Toni's Legendary Top 10 Papers List!

GU Cast

Play Episode Listen Later Jan 14, 2025 48:48


Dr Toni Choueiri, Chief of GU Oncology at Dana-barber Cancer Institute (Boston, USA) returns to GU Cast with members of his team at Dana Farber Cancer Institute to discuss our favourite lists of top GU Oncology papers for 2024. Toni has posted these now legendary lists at the end of each year on Twitter/X since the start of Covid, and they have become essential reading for anyone wanting a superb overview of top trials. Each tweet contains a top line summary of each trial and key images such as K-M curves, plus links to the original papers. A huge amount of work and a great resource. Today we are joined by Toni along with Dr Marc Eid and Dr Emre Yekeduz who helped compile this year's lists. We hear about the process behind it all, and we run through their Top 10 Bladder and Renal Cancer papers, and their Top 5 Prostate Cancer papers. The team also post their Top 10 Translational papers and Their Top 10 non-GU Oncology papers. Well done again to Toni, Marc, Emre and team! Links to the tweets below. Even better on our YouTube channelLinks:Top 10 Bladder and Renal Cancer Papers Top 5 Prostate Cancer Papers 

Keys of the Kingdom
12/28/24: An Approach to Church Organization - replay from 7/4/15

Keys of the Kingdom

Play Episode Listen Later Dec 28, 2024 155:00


(An Approach to Church Organization) Kingdom preached by Christ; At hand, for the living; Christ's doctrines; What the early Church was doing; Personality; Switched at birth story; Church Organization; Taking kingdom from Pharisees and appointment to Apostles; Pilate - procurator of Rome; Pilate's proclamation; Old testament "charity"; Servant leaders; Tens, hundreds and thousands; Levites; Perfect Law of Liberty; Incentive for ministers; Helping neighbors succeed; Mark of the Beast; "Cash"; Covetousness; Christ agreeing with Moses; One Church established by Christ; Conforming to Christ; Redefining words; Translational context; Analyzing error; Misinterpretation; Why we congregate; Biblical "study"; Church "nuts and bolts"; Flowcharting The Church?; "Church"; Free assemblies; Types of ministers; Multiple meanings of words; Jubilee; Bank capabilities; Debt forgiveness?; Inflation; Property tax; Legal title; Covetous practices; Repentance; Caring for neighbors; "Visiting" the needy; Religious orders; Church government; Voluntaryism; Armies; Rights from God; Right to make choices; Home schooling; Governing yourselves; Have you repented yet?; Playing church; Religious Order trade or business; Vow of poverty; Following foolish Pharisees; Property owned in common; Jews accepting Jesus; Modern church; vs Church government; Egyptian bondage; Casting bread upon the waters; Fire-assistance example; Flow of contributions through the structure; Kings and priests; Anarchists?; Order of Melchizedek; "Righteous king"; God-allowed governments; Ps 110:4; "word" + hey; Record; Heb 5:6; "taxis"; Body/blood example: network; Being under tribute; Heb 7:17; Kingdom vs congregation; Changing your heart and mind; "Minister"; Who does the minister work for?; Who ordains ministers?; Witness; Choice of giving; Minister functions; Office of minister?; "Corporation sole"; Levites by adoption; Brotherhood under one father; One accord; Recognizing need; Confiscating Church property; Peace. (An Approach to Church Organization (continued)) First Century Church; Modern Christians resemble Pharisees; Are we right?; Jews accepting Christ; Caring for the needy of society; Modern church concerns; Is there grace for you?; Grace = charity; "thank"; "scribes"; Acts 6 organizing; Mammon; Loving neighbors as selves; Corporation sole imitates family; Who's your father?; "parens patria"; Order defined; Republics; "Free from things public"; Thinking Kingdom; Describing Church networking; Connecting congregations; Ordaining by God; Simplicity of Christ's way; Freedom to choose; Debt; Governments exercising authority; Virtue!; Selling yourself into bondage; Essentials of kingdom; Christians leaving Jerusalem; FEMA?; Healing as Christ taught; Sacrifice; Following Holy Spirit; Forgiveness; Types of "love"; Losing sons; Laying down your life for others; Righteous mammon; "sin"; In, but not of the world; Church "service"; Our baggage and trauma; Addictions; Coming into accord with Christ; "Persons"?; Your choice; "Worship"; "Unincorporated Association"; Being Doers of the word; Sewing underwear for Levites?; Your job; Perfect Law of Liberty; Practice virtue.

BEaTS Research Radio's Podcast
The Autism Connection You Haven't Heard of

BEaTS Research Radio's Podcast

Play Episode Listen Later Dec 5, 2024 14:25


Join Kahliana Nguyen and Khaled Najjar, Translational and Molecular Medicine students, as they speak with Dr. Baptiste Lacoste, a neuroscience researcher at the Ottawa Hospital Research Institute whose recent work focuses on the critical role of the brain's vascular system in development.  The episode explores a new perspective on autism spectrum disorders (ASD) and how problems with the brain's blood vessels in early development may contribute to challenges seen in autism. Dr. Lacoste goes into depth on how these blood vessels play a role in brain growth, energy use, and behavior. By studying these interactions alongside neural and genetic factors, his research opens new avenues in how we understand autism and find better ways to address ASD. Whether you're a researcher, student, or simply curious, this episode offers an exciting new lens to the field. Learn more: Dr Baptiste Lacoste Dr Baptiste Lacoste | Faculté de médecine https://bsky.app/profile/blacoste.bsky.socialhttps://www.ohri.ca/profile/lacostelab0:02 | BEaTS and host introduction.0:22 | Introduction to Dr. Lacoste1:10 | Why did Dr. Lacoste choose to focus on the vascular system specifically?3:05 | The Neurovascular unit (NVU) and its importance in Dr. Lacoste's research on ASD5:15 | The use of mice with a 16p11.2 deletion mutation to study ASD8:43 | The novel findings were seen in Dr. Lactoste's lab study on ASD10:51 | Treatment Strategies when it comes to ASD12:03 | Limitations & Challenges Dr. Lacoste's lab faced and still faces while studying ASD13:50 | Wrapping up the episodeScience and Innovation by Vicate. All rights reserved. Listen more:https://www.jamendo.com/album/578641/science-and-innovationVicate | Jamendo Music | Free music downloadsKahliana Nguyen (Voice) & Khaled Najjar (Producer & Editor)

BEaTS Research Radio's Podcast
Cholesterol, Atherosclerosis, and Not-So-Negative Data

BEaTS Research Radio's Podcast

Play Episode Listen Later Dec 5, 2024 13:49


In this episode, Ali Abdalbari from the University of Ottawa's Translational and Molecular Medicine (TMM) program speaks with Dr. Morgan Fullerton, Professor in the Department of Biochemistry, Microbiology and Immunology at the University of Ottawa. This episode features a discussion surrounding Dr. Fullerton's most recent paper, published in the Atherosclerosis Journal (https://doi.org/10.1016/j.atherosclerosis.2024.117608). Dr. Fullerton provides an in-depth overview of his team's discoveries and offers his expertise in the field of metabolic research, highlighting the importance of model systems of disease and the implications of his research in this field.Learn more: https://doi.org/10.1016/j.atherosclerosis.2024.117608 Fullerton Lab: https://www.fullertonlab.com/0:10 | BEaTS and host introduction0:39 | Introduction to Dr. Fullerton1:39 | Podcast topic introduction1:56 | Guest welcome2:08 | Introduction to atherosclerosis3:44 | Focus of the Fullerton lab: metabolism and AMPK6:32 | Interlude: a study from collaborator Dr. Kim Loh7:04 | Concept of “negative data”7:43 | Data and challenges10:16 | Impact of research on the field of atherosclerosis11:33 | Accessibility and efficient communication in science13:23 | Podcast OutroSoundtrack by the Underground Drive. All rights reserved. Listen more:https://music.apple.com/ca/artist/the-underground-drive/1571062779https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmRPodcast credits: Ali Abdalbari (Show Host), Brianna Kore (Audio Master), Michelle Levesque (Writer Editor), Peter Noel (Producer).

ThinkResearch
Advancing Translational Science

ThinkResearch

Play Episode Listen Later Nov 18, 2024 33:16


"Translational science is really general principles for how we take scientific discoveries and basic scientific information and translate that into implementable, viable, feasible health solutions for both the patient and the provider to be able to utilize," says Michael Kurilla, MD, PhD, of the National Center for Advancing Translational Sciences (NCATS). In this episode, Kurilla discusses his work as the director of the Division of Clinical Innovation at NCATS, and the role translational research and science plays in healthcare. Harvard Catalyst is a member of the NCATS Clinical and Translational Science Awards (CTSA) Program. Transcript: https://bit.ly/3OeJta1

New Frontiers in Functional Medicine
Beyond Retinol: The Role of Urolithin A in Aging and Skin Health

New Frontiers in Functional Medicine

Play Episode Listen Later Nov 11, 2024 58:54


Talking with Dr. Julie Faitg was a powerful reminder of just how much we're discovering about mitochondria and aging. When you pair an elite mitochondrial scientist with a breakthrough nutrient like Urolithin A, the insights go beyond what you'd expect. Julie gives us this incredible look into how we can actually change the course of aging at the cellular level. This conversation made me rethink what we know about supporting long-term health and resilience, and I think it will do the same for you. It's one of those big-picture, eye-opening conversations that I can't wait for you to hear. ~DrKF CHECK OUT THE SHOW NOTES AT https://www.drkarafitzgerald.com/fxmed-podcast/ for a full list of links and resources. GUEST DETAILS Dr. Julie Faitg, PhD Email: jfaitg@timeline.com Dr. Julie Faitg is a leading expert in mitochondrial research, with over nine years of experience focusing on muscle and brain biology, and recently expanding her expertise to include skin health. Holding a PhD in Translational and Clinical Research from the Wellcome Trust Centre for Mitochondrial Research, she collaborates with renowned scientists worldwide, including Nobel laureate Eric Kandel and mitochondrial experts. Currently, Dr. Faitg serves as the Senior Translational Scientist and Regulatory Affairs Lead at Timeline, where she makes significant contributions to research and development across various organ systems in the field of mitochondrial biology. THANKS TO OUR SPONSOR Timeline: https://tinyurl.com/4x832df9 SPECIAL OFFER: Timeline is offering a 10% discount on all of their products to New Frontiers listeners. Head over to https://tinyurl.com/4x832df9 and use code KaraSkin at checkout. CONNECT WITH DrKF: Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You Group Program: https://tinyurl.com/4hvusavw Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

OncLive® On Air
S11 Ep28: Liquid Biopsy Ushers in a New Era of NSCLC Biomarker Testing: With David R. Gandara, MD

OncLive® On Air

Play Episode Listen Later Oct 28, 2024 11:29


In today's episode, we had the pleasure of speaking with David R. Gandara, MD, about biomarker testing in lung cancer. Dr Gandara is the chief medical officer of the International Society of Liquid Biopsy, the co-director of the Center for Experimental Therapeutics in Cancer, and the senior advisor to the director at the University of California Davis Comprehensive Cancer Center in Sacramento, and an adjunct clinical professor in the Translational and Clinical Research Program at the University of Hawaii Cancer Center in Honolulu.  In our exclusive interview, Dr Gandara discussed the optimal use of liquid biopsy for patients with non–small cell lung cancer (NSCLC), the ins and outs of testing for KRAS mutations, and available treatment options for patients with KRAS-mutant NSCLC.

Authentic Biochemistry
Protein Post Translational Modifications IV. Authentic Biochemistry Podcast Dr. Daniel J. Guerra 26October24

Authentic Biochemistry

Play Episode Listen Later Oct 27, 2024 52:14


References Signal Transduct Target Ther. 2024 Mar 15;9:60. Nature Reviews Molecular Cell Biology2022 23,:715–731 Kierkegaard, S. 1846. The Present Age. Jon Anderson, Chris Squire, and Bill Bruford 1971. "Heart of the Sunrise" on Fragile [lp] Tartini, G. 1730. Concerto for Clarinet and Strings https://open.spotify.com/track/07ZIuFZe7LCkOsAZURkRqs?si=eb4c096081854068 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Everything Epigenetics
From Aging to Cancer Risk in Epigenetics with Dr. Chiara Herzog

Everything Epigenetics

Play Episode Listen Later Oct 23, 2024 48:54


In this week's episode of the Everything Epigenetics podcast, Dr. Chiara Herzog and I talk about how epigenetics is making waves in the medical world and how it could change treatment. Translational scientist and research fellow Dr. Herzog provides insights from her role in the Biomarkers of Aging Consortium and her work on the TirolGESUND project, one of the largest multi-omic human lifestyle intervention trials to date. We investigate the potential applications of epigenetics in cancer detection, aging biomarkers, and preventive measures that could change the paradigm of healthcare from one that is reactive to one that is proactive. We also explore the fascinating potential of using epigenetic markers to anticipate disease before it manifests itself, particularly in the context of cancer research, and how this could impact the delivery of tailored healthcare.You'll learn about:How Dr. Herzog's background in neuroscience led her to epigeneticsRecent breakthroughs in epigenetics and why they are promising for healthcareThe potential of epigenetic markers to predict cancer risk and diagnose early stages of cancerThe setup and goals of the TirolGESUND study focusing on intermittent fasting and smoking cessationThe importance of studying epigenetic changes across different cell types and understanding the exposomeHow the exposome interacts with our epigenome and its implications for personalized medicineChapters: 00:00 Welcome and introduction02:30 Dr. Herzog's journey from neuroscience to epigenetics05:40 Recent breakthroughs in epigenetic research12:10 Epigenetics and cancer risk: promising findings19:15 TirolGESUND study: setup, interventions, and what to expect27:40 Why studying different cell types matters in epigenetics32:00 Understanding the exposome and its impact on health38:20 Future steps for advancing epigenetic biomarkers in healthcare45:00 Exciting upcoming projects in epigenetics researchSupport the showWhere to Find Us:Instagram Twitter Facebook Follow us on:Apple Podcast Spotify YouTube Visit our website for more information and resources: everythingepigenetics.com Thank you for joining us at the Everything Epigenetics Podcast and remember you have control over your Epigenetics, so tune in next time to learn more about how to harness this knowledge for your benefit.

Cancer Buzz
Live from NOC: The Hawaiʻi Cancer Consortium

Cancer Buzz

Play Episode Listen Later Oct 11, 2024 5:38


CANCERBUZZ speaks with Dr. Naoto Ueno about his NOC session titled The Hawaiʻi Cancer Consortium: An Equitable Clinical Trials Initiative. Guest:  Naoto T. Ueno, MD, PhD, FACP Director Interim Program Co-Leader, Cancer Biology Program, Translational and Clinical Research University of Hawaiʻi Cancer Center Resources: ACCC 41st National Oncology Conference

The Behavioral Observations Podcast with Matt Cicoria
Improving knee surgery outcomes with positive reinforcement: Inside JABA Series 20

The Behavioral Observations Podcast with Matt Cicoria

Play Episode Listen Later Jul 17, 2024 68:34


In the 20th installment of the Inside JABA Series, I'm joined by Drs. Brennan Armshaw, Manish Vaidya, and Sachen Mehta. As always, I'm also joined by JABA Editor in Chief, Dr. John Borerro. In this episode we discuss a fantastic paper that is out in the summer issue of JABA titled, “Surface electromyography-based biofeedback can facilitate recovery from total knee arthroplasty.” In brief, this study that examined a novel treatment approach for rehabilitating patients following knee replacement surgery. And guess what, they used simple behavioral techniques to radically improve physical therapy outcomes! Orthopedics is something that's been on my mind lately as I am recovering from a broken metacarpal bone in my hand. It's probably something of interest to others who have either had orthopedic problems themselves, or who have taken care of hose who have. However, even if you're not interested in orthopedics, I encourage you to really dig into this episode because it's just a great case study of applying our science to a novel problem that affects millions of people . As always, there are no advertisements in the Inside JABA Series shows, but I will mention that if you would like to get a CEU for listening to this episode an answering series of questions related to its content, you can find out how to do just that by clicking here. So if you would like to learn from your favorite podcast guests, especially while you're on the go, check out what we have to offer over. I should also mention that there are discounts available for multiple event purchases. I recently crunched some numbers and found out that CEU customers, on average, save almost $100 when they leverage these discount codes. Here are the links to resources mentioned in the podcast: Armshaw, Vaidya, and Mehta (2024). Surface electromyography-based biofeedback can facilitate recovery from total knee arthroplasty. Vaidya and Armshaw (2021). Surface electromyography and gamification: Translational research to advance physical rehabilitation. Inside JABA 9: Applied and Translational Research in Healthcare. The Institute for Behavior Science and Technology in Rehabilitation. Comprehensive Orthopedics and Rehabilitation. Brennan's WVU faculty page and LinkedIn. Manish's LinkedIn page.  

Something Was Wrong
S20 E13: Data Points: Minority Mental Health (featuring Dr. Corey Emanuel)

Something Was Wrong

Play Episode Listen Later Jul 2, 2024 10:17


*Content Warning: anxiety, depression, mental health, mental illness, suicidal ideation, self-harm, suicide, police brutality, and racism.*Resources:Life 4 All Minority Mental Health Resources: life4all.co/minority-mental-healthLifeline Network: https://988lifeline.org/BEAM Collective: http://beam.communityFree + Confidential Resources + Safety Tips: somethingwaswrong.com/resources *Sources:“Prioritizing Minority Mental Health.” Centers for Disease Control and Prevention, Centers for Disease Control and Prevention, 27 June 2023, www.cdc.gov/healthequity/features/minority-mental-health/index.htmlNirmita Panchal, Matthew Rae. “How Does Use of Mental Health Care Vary by Demographics and Health Insurance Coverage?” KFF, 24 Mar. 2022, www.kff.org/mental-health/issue-brief/how-does-use-of-mental-health-care-vary-by-demographics-and-health-insurance-coverage/MacMillan, Amanda. “4 Reasons for the Increase in Mental Health Conditions.” Health, 21 Aug. 2023, www.health.com/condition/depression/8-million-americans-psychological-distress. Ijoma, Bassey. “5 Common Health Conditions That Affect Minorities and Ways to Reduce Risk Factors.” SummaCare, 23 Feb. 2023, www.summacare.com/blog/entries/2023/02/5-common-health-conditions-that-affect-minorities-and-ways-to-reduce-risk-factors. Brandt, L., Liu, S., Heim, C., & Heinz, A. (2022). The effects of social isolation stress and discrimination on mental health. Translational psychiatry, 12(1), 398. https://doi.org/10.1038/s41398-022-02178-4Turner, Erlanger A., et al. “Predictors of Seeking Mental Health Treatment in Black Men: Therapy Fears and Expectations about Counseling - Community Mental Health Journal.” SpringerLink, Springer US, 8 Sept. 2023, link.springer.com/article/10.1007/s10597-023-01183-1. Reingle Gonzalez, J. M., & Connell, N. M. (2014). Mental health of prisoners: Identifying barriers to mental health treatment and medication continuity. American Journal of Public Health, 104(12), 2328–2333. https://doi.org/10.2105/AJPH.2014.302043.Sheftall, Arielle H., et al. “The Tragedy of Black Youth Suicide.” AAMC, 11 Apr. 2023, www.aamc.org/news/tragedy-black-youth-suicide. Dr. Corey Emanuel: Dr. Corey Emanuel's website: http://coreyemanuel.com Dr. Corey Emanuel's Linktree: http://linktr.ee/coreyemanuel Dr. Corey Emanuel's Instagram: http://www.instagram.com/coreyemanuel Dr. Corey Emanuel's TikTok: http://www.tiktok.com/drcoreyemanuel Men Talking Shift: http://www.instagram.com/mentalkingshiftArtwork by the amazing Sara Stewart: Instagram.com/greaterthanokayFollow Something Was Wrong:Website: somethingwaswrong.com IG: instagram.com/somethingwaswrongpodcastTikTok: tiktok.com/@somethingwaswrongpodcast Follow Tiffany Reese:Website: tiffanyreese.me IG: instagram.com/lookieboo See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dementia Researcher
Introducing the Dementia Researcher Salon

Dementia Researcher

Play Episode Listen Later Jun 25, 2024 1:03


A weekly gathering to discuss careers and research topics, inspired by 17th and 18th century salons from Paris, with a modern twist. These sessions combine livestreams, guest speakers and group chat to exchange ideas, challenge, influence, inspire and educate. After the 30 minute livestream ends, you can join the host and speakers with our others and continue to discuss the topic for a further 30 minutes (you will find this in past events). Our very first gathering is scheduled for the 26th June at 12noon BST to explore 'Tackling Sexism in Academia'. Join us LIVE or join our community to catch-up when you have time: https://communities.dementiaresearcher.nihr.ac.uk/c/events/tackling-sexism-in-academia-6284d2d8-3ddc-44f6-a618-8d7a3492f148 -- Sexism in academia is a significant issue that manifests through unequal opportunities, pay disparities, and underrepresentation of women, particularly in senior and leadership roles. Despite advancements in policies aimed at fostering equality, implicit biases and structural barriers continue to impede the progress of female academics. How can we claim to value intellectual diversity when half the population is underrepresented in academic leadership What message are we sending to the next generation of scholars if we continue to ignore the gender biases that permeate our institutions? Can academia truly progress if it fails to address the systemic barriers that prevent women from succeeding at the same rate as their male counterparts? In this salon session we will hear from our speakers and then give you the audience a chance to have your say. Speakers Georgina Menzies - is a Computational Biologist and Lecturer with a research portfolio in understanding DNA-repair and disease modifying coding mutations. Prior to this appointment Georgina held a Ser Cyrmu II Fellowship in the Dementia Research Institute at Cardiff. Georgina is involved in the Alzheimer's Research UK network in South Wales, and has helped drive the ECR steering committee for the UKDRI cross-centre theme on DNA repair and neurodegeneration into existence. Soumilee Chaudhuri - is a 3rd year doctoral candidate in Medical Neuroscience and Bioinformatics at the Indiana University School of Medicine, researching Alzheimer's Disease and Related Dementia (ADRD) in multiethnic populations. Soumilee was raised in Kolkata, India and graduated with double degrees in Neuroscience & Biochemistry from Montana State University, Bozeman as an International Merit Scholar. She works at the intersection of multi-omics and neuroimaging to characterize Alzheimer Disease (AD) therapeutics; she was competitively awarded the Alzheimer's Disease Neuroimaging Initiative Health Equity Scholar Program (ADNI HESP) fellowship. Her interests and experiences range from neurodegenerative diseases, neuroinformatics, to science communication, public health policy and diversifying academia & research spaces. She is the recent co-founder of IMPACT IN (Initiative for Mobilizing Public health Advocacy, Care, and Translational research for Alzheimer's Disease in Indiana).

Microbe Mail
Careers in Microbiology

Microbe Mail

Play Episode Listen Later Jun 25, 2024 53:15


Ever wondered what Microbiologists get up to in the laboratory? Is it all about waiting for organisms to grow, "doomsday prophecies" regarding antimicrobial resistance, and asking for a clinical correlation? The feild of Microbiology is vast, and Vin speaks to some well seasoned experts to get their take on a career in Microbiology.About our Guests: Crystal Viljoen, B.Tech Biomedical Technology: Crystal has more than 20 years of laboratory experience, and is currently working as the laboratory manager at the Infection Control Laboratory Services in Johannesburg. She is also an executive member of Legionella Action Group (LAG); and has a wealth of experience with quality management systems, including proficiency testing schemes, laboratory safety procedures and the process of laboratory accreditation, gained at the National Institute of Communicable Diseases (NICD)Andrea Prinzi, Ph.D., MPH, SM(ASCP): Dr Andrea Prinzi is currently a field medical director of US medical affairs at BioMérieux (pronounced bee oh merry you). Prior to her work in industry, Andrea was a clinical microbiologist with over 12 years of hands-on bench experience in a pediatric hospital laboratory. In 2014, she obtained her master's in public health from the Colorado School of public health with a focus in epidemiology. In 2021, she completed a PhD in clinical and translational science from the University of Colorado. As a PhD in Clinical and Translational science, her interests include antimicrobial and diagnostic stewardship (with an emphasis on pneumonia diagnostics and management), development of effective teaching methods for clinicians and the fusion of public health, clinical science and medicine to improve patient outcomes, quality improvement, infectious disease epidemiology, science communication, and implementation science. Dr. Prinzi's PhD work was clinical and translational, and focused on bridging the gap between the clinical microbiology laboratory and clinical practice. She combined clinical diagnostics, public health, clinical research and science communication to improve the way we think about and use diagnostic tests and antimicrobials. Dr. Prinzi is the clinical and public health community leader for the American Society for Microbiology's Council on Microbial sciences, as well as a regular blog writer for ASM. She is a reviewing editor for the ASM journal Spectrum, as well as an editorial advisory board member for Open Forum Infectious Diseases. She also enjoys volunteering time to help co-host the Let's Talk Micro antimicrobial resistance sub-series with her friend, Luis Plaza. Dr Keeren Lutchminarain: Dr Keeren Lutchminarain is a clinical microbiologist based at Inkosi Albert Luthuli Central Hospital. Her primary role in the NHLS is to oversee the KZN reference Tb laboratory where she is involved in interpreting routine diagnostic tests; verification of new instruments; teaching and training within the province and TB related research.YOUR FEEDBACK ON THIS EPISODE – Visit the Microbe Mail website to sign up for updates Follow on:Instagram: Microbe_MailX/Twitter: @microbemailFacebook: MicrobeMailTiktok: @

PharmaTalkRadio
The CMO as a Translational Scientist

PharmaTalkRadio

Play Episode Listen Later Jun 4, 2024 26:00


To learn more about the Chief Medical Officer Summit 360° and its associated editorials, podcasts and webcasts, please visit CMO360.org

The Fallen State (Audio)
Ed Clay Joins Jesse! (#362)

The Fallen State (Audio)

Play Episode Listen Later Jun 1, 2024 73:14


On this week's episode of TheFallenState TV, host Jesse Lee Peterson is joined by Ed Clay—He is an entrepreneur, former MMA fighter, and host of The Ed Clay Show. Ed joins Jesse to discuss his diverse and impressive career, shedding light on his journey from the MMA cage to the boardroom. As the owner of several cutting-edge medical and scientific enterprises, including the Translational and Advanced Medical Center, the Cellular Performance Institute, Legacy Cellular and Bioinformatics Laboratories, and Allogenity Biosciences, Ed shares his insights on innovation and leadership in the health and wellness industry. Don't miss this engaging conversation as they delve into Ed's entrepreneurial ventures, his commitment to advancing medical science, and the unique experiences that have shaped his remarkable career. They touch on entrepreneurship, faith, anger, forgiveness, politics, and much more!

The Fallen State TV(Video)
Ed Clay Joins Jesse! (#362)

The Fallen State TV(Video)

Play Episode Listen Later Jun 1, 2024 73:39


On this week's episode of TheFallenState TV, host Jesse Lee Peterson is joined by Ed Clay—He is an entrepreneur, former MMA fighter, and host of The Ed Clay Show. Ed joins Jesse to discuss his diverse and impressive career, shedding light on his journey from the MMA cage to the boardroom. As the owner of several cutting-edge medical and scientific enterprises, including the Translational and Advanced Medical Center, the Cellular Performance Institute, Legacy Cellular and Bioinformatics Laboratories, and Allogenity Biosciences, Ed shares his insights on innovation and leadership in the health and wellness industry. Don't miss this engaging conversation as they delve into Ed's entrepreneurial ventures, his commitment to advancing medical science, and the unique experiences that have shaped his remarkable career. They touch on entrepreneurship, faith, anger, forgiveness, politics, and much more!

Simulcast
186 Advances in Simulation: Translational Simulation Revisited

Simulcast

Play Episode Listen Later May 27, 2024 39:14


In our latest Advances in Sim collaborative episode, we explore how translational simulation has evolved in the last 6 years.  Ben interviews the authors of “Translational simulation revisited: an evolving conceptual model for the contribution of simulation to healthcare quality and safety”, Prof Gabe Reedy and our own Prof Victoria Brazil in order to explore their new paper.  Together we discuss how the concepts of Purpose, Process and Conceptual Foundations underpin the strategic design and delivery of projects using translational sim. 

NEJM AI Grand Rounds
Translational AI in Medicine: Unlocking AI's Potential in Health Care with Nigam Shah

NEJM AI Grand Rounds

Play Episode Listen Later May 15, 2024 55:12 Transcription Available


In this episode of the NEJM AI Grand Rounds podcast, Dr. Nigam Shah, a distinguished Professor of Medicine at Stanford University and inaugural Chief Data Scientist for Stanford Health Care, shares his journey from training as a doctor in India to becoming a leading figure in biomedical informatics in the United States. He discusses the transformative impact of computational tools in understanding complex biological systems and the pivotal role of AI in advancing health care delivery, particularly in improving efficiency and addressing systemic challenges. Dr. Shah emphasizes the importance of real-world integration of AI into clinical settings, advocating for a balanced approach that considers both technological capabilities and the systemic considerations of AI in medicine. The conversation also explores the democratization of medical knowledge, why open-source models are under-researched in medicine, and the crucial role of data quality in training AI systems. Transcript.

MIB Agents OsteoBites
Creating a translational genomic framework for canine osteosarcoma: updates on the NCI DOG2 project

MIB Agents OsteoBites

Play Episode Listen Later May 10, 2024 64:00


Dr. Amy LeBlanc is a board-certified veterinary oncologist, Senior Scientist and Director of the CCR Comparative Oncology Program at the National Cancer Institute, NIH. In this position, she directly oversees and manages the operations of the Comparative Oncology Trials Consortium (COTC), which designs and executes clinical trials of new cancer therapies in tumor-bearing pet dogs. She joins us on OsteoBites to discuss findings as we work toward genomic and transcriptional profiling of canine osteosarcoma and how the results relate to human osteosarcoma. The DOG2 project was launched to better understand the relationships between the disease in dogs and humans -- all to make it better for all patients, be they 2-legged or 4 legged!

The Immunology Podcast
Ep. 77: “Computational and Translational Immunology” Featuring Dr. Caleb Lareau

The Immunology Podcast

Play Episode Listen Later Apr 23, 2024 78:11


Dr. Caleb Lareau is an Assistant Professor at Memorial Sloan Kettering Cancer Center. His lab aims to understand how cells in our bodies adapt, expand, and evolve during the course of our lives, particularly in the immune system. He talks about cross-training in bioinformatics and immunology, and herpesvirus reactivation in CAR T cells.

Hope and Help For Fatigue & Chronic Illness
EP18: Translational Research for Gulf War Illness Treatment

Hope and Help For Fatigue & Chronic Illness

Play Episode Listen Later Apr 16, 2024 37:00


Translational research is now a key player in advancing studies for Gulf War Illness. In this episode, Dr. Amanpreet Cheema, Program Director of Research Operations at the Institute for Neuro-Immune Medicine, discusses how the experts and researchers at the Institute effectively collaborate to translate scientific discoveries into real-world solutions for Gulf War Illness.  Joined by Haylie Pomroy, Dr. Cheema also explores the ongoing research and initiatives addressing health issues affecting Gulf War veterans. They also discuss studies involving Bacopa monnieri, glutamate, N-acetyl cysteine, and B-cell suppression, aiming to help veterans and individuals heal from chronic illness symptoms. Dr. Amanpreet Cheema, PhD, is the Director of Office of Clinical Research at the Institute for Neuro-Immune Medicine. With a background in nutritional biochemistry, she focuses on identifying natural products and nutraceuticals as potential therapies for complex illnesses. Dr. Cheema oversees clinical research development and operations, having previously coordinated operations for a multi-site consortium. She also serves as vice chair on NSU's Institutional Review Board and holds an Assistant Professor position at INIM, Department of Nutrition Science. Her research aims to create profiles of complex illnesses based on nutrition and disease symptomatology, facilitating patient subgrouping and identifying disease targets. LinkedIn: https://www.linkedin.com/in/amanpreet-cheema-phd-ms-55037158/ —------------------------------------------------------------------------------------------ Thank you for tuning in to the Hope and Help For Fatigue and Chronic Illness Podcast. Sign up today for our newsletter.

Dr. Chapa’s Clinical Pearls.
The Steroids Saga: New Data, New Debate, New News.

Dr. Chapa’s Clinical Pearls.

Play Episode Listen Later Apr 1, 2024 38:27


The current dose and schedule for antenatal corticosteroids (ACS) follows the original publication by Liggins and Howie in 1972. That dose and schedule was based on sheep models from the 1960s. The dose in current use had never been evaluated to minimize exposures while assuring efficacy. New pharmacokinetic and pharmacodynamic data is calling into question whether the current dose and schedule is necessary. Translational research in animal models indicate that a constant, low concentration fetal exposure to ACS is sufficient for lung maturation, resulting in lower fetal exposures. In this episode, we will summarize a new clinical commentary published in AJOG in March 2024 highlighting the current state and controversies regarding ACS for threatened preterm labor.

Dr Dad
Excessive Screen Time Can Cause Virtual Autism.

Dr Dad

Play Episode Listen Later Mar 6, 2024 10:50


Welcome to podcast by Dr Dad, the podcast where we delve deep into the intersection of technology, child development, and mental health. I'm your host,Dr Gaurav Nigam, MD, and in today's episode, we embark on a journey to understand the profound effects of excessive screen time on children, particularly in relation to autism spectrum disorder (ASD) and the emergence of what some experts term as "virtual autism." In an age where screens dominate our daily lives, from smartphones and tablets to computers and gaming consoles, children are growing up in a digital landscape unlike any previous generation. While technology undoubtedly offers myriad benefits, it also poses significant risks, especially when it comes to the delicate process of child development. Excessive screen time refers to prolonged and unrestricted use of electronic devices, often to the detriment of other activities essential for healthy growth and learning. With the rise of virtual classrooms, online gaming, and social media, children are spending more time than ever in front of screens, blurring the lines between virtual and real-world experiences. But what happens when screen time surpasses healthy limits? How does it impact the developing minds of children, particularly those on the autism spectrum? These are the questions at the heart of our discussion today. Autism spectrum disorder is a neurodevelopmental condition characterized by challenges in social interaction, communication, and repetitive behaviors. While the exact causes of autism remain elusive, research suggests a complex interplay of genetic, environmental, and neurological factors. In recent years, experts have observed a concerning trend: the convergence of excessive screen time and symptoms resembling those of autism. This phenomenon, often referred to as "virtual autism." One of the hallmarks of autism spectrum disorder is difficulty in navigating social interactions and understanding nonverbal cues. Children with autism may struggle to engage in reciprocal conversations, maintain eye contact, or interpret facial expressions—all essential skills for building meaningful relationships. Furthermore, prolonged exposure to screens may disrupt the development of neural circuits responsible for processing social and emotional information, further complicating the social deficits associated with autism. Studies have shown that excessive screen time in early childhood is linked to delays in language acquisition, attentional difficulties, and reduced empathy—a trifecta of challenges for children already grappling with the symptoms of autism. But the impact of excessive screen time extends beyond social interaction and communication. Research suggests that prolonged screen exposure can alter brain structure and function, particularly in regions involved in attention, memory, and executive functioning. References: Cristiana BĂLAN, Virtual Autism and Its Effects On the Child's Evolution https://www.afahc.ro/ro/afases/2018/43-CristinaBalan.pdfHermawati, D., Rahmadi, F. A., Sumekar, T. A., & Winarni, T. I. (2018). Early electronic screen exposure and autistic-like symptoms. Intractable & rare diseases research, 7(1), 69–71. https://doi.org/10.5582/irdr.2018.010071.Bedrosian, T. A., & Nelson, R. J. (2017). Timing of light exposure affects mood and brain circuits. Translational psychiatry, 7(1), e1017. Autism Parenting Magazine is a very good source for reading further. A lot of this podcast has been taken from that website. https://doi.org/10.1038/tp.2016.2622.Chonchaiya, W., & Pruksananonda, C. (2008). Television viewing associates with delayed language development. Acta paediatrica (Oslo, Norway : 1992), 97(7), 977–982. https://doi.org/10.1111/j.1651-2227.2008.00831.xMiller, V., & Gomez-Nicola, D. (2014). How can we exploit the brain's ability to repair itself?. Expert review of neurotherapeutics, 14(12), 1345–1348. https://doi.org/10.1586/14737175.2014.985659,

Cell & Gene: The Podcast
The Future of Rare Diseases with The Jackson Laboratory's Rare Disease Translational Center's Cat Lutz

Cell & Gene: The Podcast

Play Episode Listen Later Feb 29, 2024 27:31


Rare Disease Day is February 29, 2024, and in honor of this important day, Cell & Gene: The Podcast Host Erin Harris sits down with Jackson Laboratory's (JAX) Rare Disease Translational Center (RDTC)'s VP, Cat Lutz. They discuss RDTC's mission, the specific qualifications that make up a rare disease, how the study of rare diseases can potentially advance progress in common diseases, and much more. 

Fractals: Life Science Conversations
The Necessity of Nuclear Medicine: Radiopharmaceutical Development and Translational Decision-Making with Guest Sandy McEwan

Fractals: Life Science Conversations

Play Episode Listen Later Feb 14, 2024 32:07


Former Chief Medical Officer, Vice President of Nuclear Medicine, and long-time academic physician—that's our in-house nuclear medicine expert, Dr. Sandy McEwan. From research and publications in the academic space to hands-on development of novel SRTs, Sandy's expertise is as developed as it is broad. Join Sandy and host Colin Miller on this episode of Fractals to hear key insights on: The evolving landscape of nuclear medicine, radioisotope therapy, and radiopharmaceuticals in light of technological advancements, and a glimpse into their future. Defining success metrics in nuclear medicine and how they are influenced by treatment modalities.The collaborative potential between industry and academia in advancing groundbreaking treatments and introducing new options for patients.The importance of prioritizing patient-centered approaches in the advancement of radiopharmaceutical therapies. 

Commonwealth Club of California Podcast
Innovative Patient-Centered Care for Cancer

Commonwealth Club of California Podcast

Play Episode Listen Later Feb 3, 2024 53:10


The current system of cancer care is not built to optimize for patients, according to our speakers. Clinical trials optimize for sponsor outcomes. Hospitals and clinics optimize for payer reimbursement. Translational research optimizes for publication impact. Electronic health records are optimized for billing efficiency. Join us in-person or online as Katie Coleman (cancer survivor, founder of the Chromophobe and Oncocytic Tumor Alliance and team member at the Rare Cancer Research Foundation) and Rare Cancer Research Foundation President Marshall Thompson advocate for a better way. Putting the patient at the center of the cancer research and care ecosystem requires new tools and capabilities. Patients are uniquely positioned—as both ultimate source and beneficiary of all cancer-related samples, data, and findings—to power a change in the way we approach oncology innovation in the clinic and in the laboratory. The first steps toward a patient-centered oncology research, collaboration and clinical exploration program are possible today, and RCRF is building toward a future that empowers all cancer patients to participate in and benefit from the promises of modern personalized medicine. About the Speakers Katie Coleman is a devoted and innovative software engineer whose experiences navigating an ultra-rare kidney cancer profoundly shaped her career and purpose. Her passion lies not only in finding solutions that improve that patient experience but also in leveraging her technical expertise to translate these solutions to reality in ways that provide patients opportunities to enable research and medical advances. As the product engineering lead at RCRF, Coleman's role transcends typical engineering boundaries. She marries her technical expertise with a personal commitment to advocacy, striving to propel research and improve outcomes for those battling rare cancers. Coleman is founder of the Chromophobe and Oncocytic Tumor Alliance. Marshall Thompson is a multi-disciplinary scientist, software engineer, and business leader with a strong interest in applying cutting-edge software practices to genomic-scale biological problems. Thompson completed his undergraduate studies at the University of New Mexico, where he earned degrees in biology and computer science. Marshall went on to earn a doctorate in genetics and genomics from Duke University. Thompson has a wealth of experience in the software and business industry, with skills in software architecture and development, consulting, product development, technical marketing, sales engineering, support, and support management. MLF ORGANIZER: Gerald Anthony Harris A Technology & Society Member-led Forum program. Forums at the Club are organized and run by volunteer programmers who are members of The Commonwealth Club, and they cover a diverse range of topics. Learn more about our Forums. Learn more about your ad choices. Visit megaphone.fm/adchoices

Project CASK Podcast
PC has launched first RFA! What's next?

Project CASK Podcast

Play Episode Listen Later Jan 18, 2024 6:21


We've launched our first Request for Applications (RFA)! What's in it and what's next? Check out this message from Hitomi Kubo of Project CASK, breaking down the basics of this exciting new step in our collective journey to kick CASK! ***** Project CASK has launched its first Request for Applications, building on the discussion at the CASK Think Tank on 4 December 2023. Managed in collaboration with the Orphan Disease Center, University of Pennsylvania, we are seeking proposals that will make a significant impact on the CASK community and accelerate our path to effective therapeutics for CASK gene disorders in one of two categories: Seed grants of up to $50,000 for 12 months: These grants will support studies to better understand CASK gene disorders and/or support clinical studies. Proposals should respond to key gaps in the knowledge of or research assets for CASK disorders that are critical to the pursuit of therapeutic development, including future clinical trials. Translational grants of up to $250,000 for 24 months: These grants will drive forward translational research from drug repurposing and small molecules to gene therapies including forward-looking approaches to address current limitations specific to the CASK gene, RNA editing or other RNA based approaches, and novel techniques for x-linked neurological disorders.

UEG Journal
Effect of miR-10b in regulating gut barrier dysfunction in diabetes and GI dysmotility

UEG Journal

Play Episode Listen Later Jan 15, 2024 18:35


Dr Ahsen Ustaoglu interviews Dr Rajan Singh and Dr Hannah Zogg from the University of Nevada, USA, on their study which investigated the role of microRNA 10b-5p in regulating gut barrier function in an in vivo model of diabetes and gastrointestinal dysmotility, important mechanistic work in the field of Neurogastroenterology.

The Yogic Studies Podcast
43. Christopher Jain Miller | Embodying Translational Yoga

The Yogic Studies Podcast

Play Episode Listen Later Dec 14, 2023 64:07


In this episode we speak with Christopher Miller about his recent monograph, Embodying Transnational Yoga: Eating, Singing, and Breathing in Transformation (Routledge 2023) and his upcoming online course at Yogic Studies. We begin by discussing his academic background and how he first got into critical Yoga and later Jain Studies, his experiences as a practitioner of yoga in Santa Monica, California, and how he developed his dissertation project that would eventually become the book. We discuss the importance of shifting Modern Yoga Studies beyond the study of postural yoga, exploring his three book chapters which analyze the practices of eating (yogic diet), singing (kīrtan), and breathing (prāṇāyāma). We discuss the origins and history of the harmonium, how yoga intersects with food and pollution studies, and question what it means to practice prāṇāyāma in a heavily polluted Indian city. We conclude the conversation by previewing Miller's upcoming online course, YS 127 | Embodying Transnational Yoga.Speaker BioDr. Christopher Jain Miller is the co-founder, Vice President of Academic Affairs, and Professor of Jain and Yoga Studies at Arihanta Institute. Miller completed his PhD in the study of Religion at the University of California, Davis. He is a Visiting Researcher at the University of Zürich's Asien-Orient-Institut and Visiting Professor at Claremont School of Theology where he co-developed and co-runs a remotely available Masters Degree Program focusing on Engaged Jain Studies. His current research focuses on Modern Yoga and Engaged Jainism. Christopher is the author of a number of articles and book chapters concerned with Jainism and the practice of modern yoga. He is the author of Embodying Transnational Yoga: Eating, Singing, and Breathing in Transformation (Routledge 2023) as well as co-editor of the volumes Engaged Jainism: Critical and Constructive Approaches to the Study of Jain Social Engagement (SUNY Forthcoming) and Beacons of Dharma: Spiritual Exemplars for the Modern Age (Lexington 2020).LinksYS 127 | Embodying Transnational YogaArihanta Institutehttps://uzh.academia.edu/ChristopherMillerEmbodying Transnational Yoga: Eating, Singing, and Breathing in Transformation (Routledge, 2023) -- use code ESA32 before Dec 31, 2023 to receive a 20% discount.

A Tale of Two Hygienists Podcast
Translocation Therapy for Tooth Replacement - Fast Facts: Perio Edition with Katrina Sanders, RDH

A Tale of Two Hygienists Podcast

Play Episode Listen Later Dec 11, 2023 4:57


Have you ever wondered what would happen if we could use natural teeth instead of implants? Like, could we gently extract a 3rd molar and move it up in place of an extracted 1st molar? Listen to this fascinating Fast Fact with Katrina Sanders! Resources:More Fast Facts: https://www.ataleoftwohygienists.com/fast-facts/ Katrina Sanders Website: https://www.katrinasanders.com  Katrina Sanders Instagram: https://www.instagram.com/thedentalwinegenist/  Pini Prato, G., Franceschi, D., Pace, R., & Di Gianfilippo, R. Translational approach to tooth autotransplantation: A 27‐year case study. Clinical Advances in Periodontics.

Rural Health Leadership Radio™
378: A Conversation with Dr. Kevin Bennett

Rural Health Leadership Radio™

Play Episode Listen Later Nov 21, 2023 37:22


Collaboration and connection are aspects we often emphasize in rural health. The rural advantage allows us to collaborate with each other and uniquely connect with our communities.  Our guest this week on Rural Health Leadership Radio is no stranger to collaboration. We are delighted to share with you our conversation with Kevin Bennett, a Professor at the University of South Carolina School of Medicine, Chair of the Department of Translational and Clinical Sciences, Director of the South Carolina Center for Rural & Primary Healthcare, and the Research Center for Transforming Health.  Dr. Bennett discusses his work in rural health, emphasizing the importance of addressing food insecurity and bridging gaps in healthcare access. He highlights the need for comprehensive solutions, including collaborations with medical education institutions. We also explore how to attract young professionals to a rural lifestyle. “Rural is more than a label, there's a beauty to it and a strength in the community connection.” -Kevin Bennett Dr. Bennett is Professor and Chair in the Department of Translational and Clinical Science, at the University of South Carolina School of Medicine, in Columbia, SC. He serves as the Director of the Research Center for Transforming Health and Director of the South Carolina Center for Rural and Primary Healthcare. He also serves on the National Rural Health Association's Board of Trustees and as President-Elect (2024).  His work focuses on care delivery for vulnerable and underserved populations and how policies and legislation affect these populations.  He has also worked extensively with community organizations, rural health networks, healthcare systems, and state agencies to create, facilitate, and evaluate the impact of innovative care delivery programs.

Authentic Biochemistry
BioMedical PortraitVI.C.7 IEI/IEM pathobiochemistry involves bioenergetics, transcriptional , translational, and post-translational modification sequalae.DJGPhD.19.11.23 Authentic Biochemistry.

Authentic Biochemistry

Play Episode Listen Later Nov 19, 2023 30:00


References Front Immunol. 2022; 13: 950536. Inflamm Res. 2018 Oct;67(10):813-828 Mol Biol Rep. 2023; 50(8): 6963–6974. Front Immunol. 2023; 14: 1151166 Dr Guerra: Graduate biochemistry lecture archive Schubert.F. 1827.December.Impromptu #3 in G flat major performed by Khatia Buniatishvili https://youtu.be/LUp2u9wI1fY?si=hhiUmiyXyQ78Qtaw and "Questions" Manfred Mann 1976. https://youtu.be/qvvstrKLvts?si=-I8bGmB2oC3FpPLw --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Andy‘s PERSONAL DEVELOPMENT
Translational Lift Coaching WITH WALT MORGAN

Andy‘s PERSONAL DEVELOPMENT

Play Episode Listen Later Oct 30, 2023 48:26


Walt Morgan: Transformational Leadership Coach: Since I was five, I wanted to fly helicopters. So I did. I was in the U.S. Navy for 23 years as a designated helicopter pilot. Before I retired from the Navy, I had assumed that I would fly for the rest of my life (helicopters or other) - it was my passion and it was what I was trained to do. But I felt a nudge from the universe; a new calling. It happens that in my last four years in the Navy, I was assigned as a professor teaching leadership at the University of Colorado. I became fascinated with leadership and learned how much I had to learn. Through that work, I realized that I felt called to serve others in their personal leadership journeys. So when I retired, I decided to leave aviation in my past and work in leadership development. First, in the corporate setting as an in-house facilitator, and then as an independent coach. For me, the journey since retirement has been characterized by powerful emotional, spiritual, somatic, and cognitive growth. I feel so fortunate to be able to serve others in their personal leadership journeys!  Walt Morgan is a professional Integral Coach who partners with clients from all walks of life to achieve the personal and professional developmental goals that are most important to them. .      https://tliftcoaching.com/  https://linkedin.com/in/walt-morgan

Do You F*****g Mind?
256. Fave Ep: You're setting the bar TOO low

Do You F*****g Mind?

Play Episode Listen Later Oct 29, 2023 35:58


Do you know if you are setting the bar too low for yourself, your relationships and your career / abilities? In this episode, I cover what happens when you do that, and why it is important to turn that around so you can start expecting and receiving more out of life. Brain Fact: Explaining Urbach-Wiethe disease. of people who don't experience the physiological aspects of the fear response. Urbach-Wiethe disease on Wikipedia https://bit.ly/urbachwiethe . Koen N, Fourie J, Terburg D, Stoop R, Morgan B, Stein DJ, van Honk J. Translational neuroscience of basolateral amygdala lesions: Studies of Urbach-Wiethe disease. J Neurosci Res. 2016 Jun;94(6):504-12. doi: 10.1002/jnr.23731. PMID: 27091312. LINKS Send your Listener question to info@dyfmpod.com  Join DYFM + https://bit.ly/dyfm-membership . Subscribe to the DYFM 6 week course https://bit.ly/dyfm-course . Follow @dyfmpodcast on Instagram  Follow @alexispredez on Instagram   Join the DYFM Facebook Group https://bit.ly/dyfm-group . Follow @listnrentertainment on Instagram  CREDITS Host: Alexis Fernandez Executive Producer & Editor: Elise CooperDigital Producer: Zoe Panaretos  Social Producer: Shania MaguaManaging Producer: Sam Cavanagh  Find more great podcasts like this at www.listnr.com/  See omnystudio.com/listener for privacy information.

Jack Westin MCAT Podcast
Control your DNA! Transcriptional and Translational Control I Jack Westin MCAT Podcast

Jack Westin MCAT Podcast

Play Episode Listen Later Oct 12, 2023 45:14


How do we control what DNA is expressed? Azaii and Phil talk about all the ways that our body controls the rate of protein production via regulating transcription and translation. About Jack Westin - The team at Jack Westin is dedicated to a single goal: giving students the highest quality learning resources. Jack Westin understands that students can't crush the MCAT without the perfect blend of critical thinking and fundamental science knowledge. To this end, Jack Westin is dedicated to providing students with cutting edge comprehensive tools, courses, and practice materials. The Jack Westin MCAT science and CARS courses, taught by the world's best and most engaging MCAT instructors, are designed to do more than just teach students the MCAT—it supercharges studying and encourages lifelong learning. Want to learn more? Shoot us a text at 415-855-4435 or email us at podcast@jackwestin.com!

Doctor's Inn
Ep 23: Tony Adkins, P.A. — Thinking Outside the Box with Pediatric Patients, Working in Pediatric Neurosurgery, Orthopedics, & Emergency Medicine, Translational Knowledge from the Military, and More

Doctor's Inn

Play Episode Listen Later Oct 1, 2023 32:54


Tony Adkins is a Physician Assistant in pediatric neurosurgery at Children's Hospital of Orange County. He also works at the emergency department at St Joseph's Hospital. He is known as the “dancing doc” on social media and his philosophy on treating patients is to individualize each patient on the best practice rooted in a recovery model. Due to his widely-recognized uplifting nature as a provider, Tony has been featured on many television shows such as Good Morning America and Good Day LA. Tony graduated from the University of Washington School of Medicine's PA program and got his masters in public health, global health, and epidemiology at Loma Linda University. He had a non-traditional path to medicine as he initially served in the army for nine years. In his free time, Tony goes out with his family, wins gladiator awards for obstacle courses, and hikes the Grand Canyon. If you want to see empowering interactions with neurosurgical pediatric patients, you can follow him on Instagram at t_malone3. If you want to support Doctor's Inn, here are some easy ways: 1. Leave a rating! We welcome all feedback! 2. Visit our website at www.doctorsinnpodcast.com to gain access to in-depth resources and our YouTube channel at Doctor's Inn Podcast to watch short engaging animated videos 3. Follow our socials @doctorsinnpodcast

The Vertue Podcast
#8 - How to be healthy without spending all your money | Health on a Budget

The Vertue Podcast

Play Episode Listen Later Sep 20, 2023 28:40


In today's podcast, amidst the rising cost of living and the resulting anxiety amplified by media, I'm hoping this episode provides a grounded and affordable approach to health and wellness. We'll delve into the impacts of financial stress on our health, introduce the Diathesis-Stress Model to understand individual stress susceptibility and offer cost-effective solutions for relaxation, fitness, nutrition, and psychological assistance. I'll also guide you on effectively scheduling these practices throughout your week. Remember to subscribe for insightful and actionable content, as this podcast strives to serve comprehensive and applicable knowledge for your well-being. RESOURCES: 1. Diathesis Stress Model Arnau-Soler, A., Adams, M. J., Clarke, T. K., MacIntyre, D. J., Milburn, K., Navrady, L., Generation Scotland,, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Hayward, C., McIntosh, A., & Thomson, P. A. (2019). A validation of the diathesis-stress model for depression in Generation Scotland. Translational psychiatry, 9(1), 25. https://doi.org/10.1038/s41398-018-0356-7 (This is a nice little open-access paper for y'all that want to geek out on it's application to depression) 2. Paper in Nature on Breath Work benefits on reducing self-reported stress Fincham, G.W., Strauss,Fincham, G.W., Strauss, C., Montero-Marin, J. et al. Effect of breathwork on stress and mental health: A meta-analysis of randomised-controlled trials. Sci Rep 13, 432 (2023). https://doi.org/10.1038/s41598-022-27247-y Psychology on a Budget - Crisis Lines in different places (I've tried to narrow these lists down based on the top 5 locations y'all are listening in from - apologies if I miss your country): 1. UK - https://tinyurl.com/UK-Crisis-List 2. USA - https://tinyurl.com/USA-Crisis-Line 3. AUS - https://tinyurl.com/AUS-Crisis-Lines 4. Germany - https://tinyurl.com/Germany-Crisis-Rescourses 5. Canada - https://tinyurl.com/Canada-Crisis-Lines Dive into the truth of health and fitness: sign up for our weekly emails packed with evidence-based, actionable insights that help you cut through the BS - https://manage.kmail-lists.com/subscriptions/subscribe?a=SQjK5R&g=Uqc4pJ TRAIN WITH ME: www.shonavertue.com --- Send in a voice message: https://podcasters.spotify.com/pod/show/thevertuepodcast/message

Blair Technique Podcast
Postural distortions, cardiopulmonary function, and athletic performance - Rapid Research Review

Blair Technique Podcast

Play Episode Listen Later Sep 12, 2023 21:33


On this rapid research review, we break down a recent publication titled: "Translational and Rotational Postural Aberrations Are Related to Pulmonary Functions and Skill-Related Physical Fitness Components in Collegiate Athletes" J Clin Med. 2023 Jul; 12(14): 4618.Published online 2023 Jul 11. doi: 10.3390/jcm12144618 Download the full text article here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380693/ We discuss: the study design and aim correlations related to posture and cardiopulmonary testing correlations related to posture and athletic performance testing clinical application for upper cervical chiropractors If you have articles you'd like us to review, send them to blairchiropodcast@gmail.com. Thanks for listening!